LOCUS       c00018_gnlPro..        22942 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DHNHCICD_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:04:18
            Original ID  :: gnl|Prokka|DHNHCICD_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22942
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..282
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 59.8; E-value:
                     5.8e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_1"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5e-19, bitscore:
                     59.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AASAPVAAPAPAPAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGTP
                     VKAGDQILTLEAMKMNTIIYAPASGTLTAFCVNPGDTVQEGQALAKIG"
     protocluster    1..22942
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2903:12942]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2904..12942
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..22942
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22942
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             361..2025
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OAD_beta"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="OAD_beta (E-value: 6.2e-159, bitscore:
                     520.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFDSLITFLQGMGVFSLSWQMVGMWGIAILLLYLGVAKQYEPL
                     LMVPIAFGALIANIPDNGMLITQLNQQVISSNEQGEVTATSLNNVGYLRVHVAPLQQAP
                     SKVPANLTTPESRSQYQEIMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSL
                     TVDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGNRIPVDLKTQKLEP
                     LVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIFLGVGALTDFGPLL
                     AAPRTLLLGAAAQVGVAATFFMALFMGFTPNESASIGIIGGADGPTSIFLTMKLAPHLL
                     GAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEKLFFAVLVTIVTIL
                     LIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTSVGLTMQGDRFLQS
                     ETLLIILLGIVAFGVATAGGVIAAKIMNLIWRKNPVNPLIGSAGVSAVPMAARVSHNVG
                     QKYDPSNYLLMHAMGPNVAGVIGTAVIAGYYIATLAK"
     CDS             2063..2842
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MNSAASFSTPPEEEGPCGDWTYHEWAEAFSTNDLARALPPGHIAV
                     CRVQTGGRGRFNRKWIGEEGGLWASFTVPLSAPEDTAAGVHWGHLPLVAGLALFNMLRG
                     MGLDSVRLRWPNDLLAGKSKLAGILVERPAENMAVIGIGINVFNDVSSIAGEIKDPPAR
                     LADLVRDCPSLHAVMASLGSHLNQVLSVFSHGGVPALQEGLSRAWAGERPVSILTDDET
                     VRGIFTGIDDQGNPVLSLPAGTVRTIPAHLINRLLEE"
     CDS             2904..4400
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hydro"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: AcetylCoA_hyd_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="AcetylCoA_hyd_C (E-value: 3e-46, bitscore:
                     148.9, seeds: 181, tool: rule-based-clusters)"
                     /sec_met_domain="AcetylCoA_hydro (E-value: 2.1e-43,
                     bitscore: 140.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYKVLTPEEAASLIKHGHHIGLSGFTPAGTAKAVTAALAKIAEA
                     EHEKGNPFQVSVFTGASTGDSCDGILSRAKAIRYRAPYTTNVDFRKAVNNGEIAYNDIH
                     LSQMAQEVRYGFMGNVDIAIIEACEVTADGKIYLTAAGGIAPTICRLADKIIVELNAAH
                     SKSAMGLHDVYEPLDPPYRREISIFKPSDRIGKPYIQVDPKKIVGVVETNWPDEARSFA
                     AADPLTDKIGQNVADFLAADMKRGIIPSTFLPLQSGVGNIANAVLGALGRDKTIPAFEM
                     YTEVIQNSVIGLIREGRVKFGSACSLTVTNDCLEGIYRDMDFFRDKLVLRPSEISNSPE
                     VIRRLGVISINTAIEADIYGNVNSTHIGGTKMMNGIGGSGDFTRNAYISIFTCPSVAKD
                     GKISAIVPMVSHHDHTEHDVNIIITEQGVADLRGKSPKERAQTIIENCVHPDYKNILWD
                     YLKLSDGKAQTPQSIRAALGMHAELARSGDMKNVDWAQYK"
     CDS             4520..5221
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MNWMIYPAARAFIKVCSVLFGTGAAAAVLIHLFMPFFLRSPRTAA
                     PFLLLGTGAELLSILSLSFLMFWGVRVLLASRGSRITRNLSMLAFLPALYALLIPFAGM
                     PVPSQYTEMDRVWEAVLLLSAVTSFFSFPYTAGYGAAGRRLFLAWGIAAAGCGLQSALF
                     FLAVLLRQFLSTAVPSLAAPVAWLAVLLSCGLEIMLAALSAILAQRLFKEVMSIASMPE
                     PIDPSMPGNRP"
     CDS             complement(5425..6288)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MKGIVLAGGSGTRLHPVTLSVSKQLLPVYDKPMVYYPISVLMLAG
                     IREILVISTPRDLPLYRDLLGDGSRFGVSFKYREQPRPEGLAQAFIIGEEFIGKDSVAL
                     VLGDNIFYGRGLTEKLRRAAELTSGATIFGYQVHDPQRFGVVEFNEEGKAVSIEEKPPR
                     PKSDIAVTGLYFYDNRVVEIAKRIPKSSRGELEITSVNQEYLKQGLLRVEKLARGYTWL
                     DTGTHDTLLEASMFVRTLEHHQGFKVACLEEIAFNNGWISQETLRSQAGAMNNNGYGRY
                     LDELVK"
     CDS             complement(6298..7350)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 9.5e-99, bitscore:
                     322.6, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIVTGGAGFIGSNLVRLLLERGHEVLNIDALTYAGNIHSLDGS
                     ADSPAYRFLHADVRDASLMRRTLREYAPDWVMHLAAESHVDRSIDDPGNFMTTNVMGTF
                     SMLQAALEYYRSLEGEKKERFRFHHISTDEVYGSLGKEGLFTESTPYRPHSPYSASKAS
                     SDHLVRAWHDTYGLPVLITNCSNNYGPYQFPEKLIPVVILKALGGEPIPVYGKGENVRD
                     WLYVGDHCEALLTVVSCGKPGETYNIGGNNEKTNLELVELLCSHLDELRPRPDGRSYRE
                     QISFVQDRPGHDLRYAIDASKIRRELGWTPRQDHSSGFRKTIQWYLDHEEWWRGILSGE
                     YRLERLGTNG"
     CDS             complement(7482..8399)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MNPAIKAAVDHARQLGMNPYVVYDGLEGLIDGKIKEATRELTNDM
                     IYRGGTLLRSSRSKRFFDYEFRKQAYEHLKERNIDKLIIMGGDGSFRALNDFFNDFEVP
                     FAGIPATIDNDIAGTDYCLGVDTAQNVILDCIDSVRDTARSHHRAFVIETMGRDCGYLA
                     MTTALCSAADICIVPEIPYDLESIYKRLQPVINEEGSCIIAVVAEGTRVAQYLTRWLTE
                     RAGMDTRLTVLGHVQRGGSPTARDRLMGTRFATRAVEALNNGDINQIMVYHDGQYGYAS
                     LDSVAGQQYSVNQDIINLCRELSC"
     CDS             8555..9286
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MNDTAAAILKATAALRDGTEKLRFESPVHVTYNPLTYAWGPHEQY
                     VRTYGNGEKSHLFLGMNPGPFGMAQTGVPFGEVDAVVNWLHIRGEVGRPEHTHPKRPVE
                     GFGCPRSEVSGRRLWGLFAEAFGTAENFFRHNYVANYCPLIWMGATGANITPDKLPAEQ
                     RAAVDAVCMEHLLSLITILNPHTLVGVGAYATQKLRDAASRLPGKSFTIGTLLHPSPAS
                     PIANKLWPEHPIQQLKELGIL"
     CDS             9655..11121
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MAISDYIVTIGLEVHCQIKTKSKMFCSCETGFGFEPNTRVCPTCL
                     GLPGALPVLNEFAIERTLLTGLMLGCSSPEISQWDRKNYFYPDMAKNYQTSQLDLPLCL
                     GGEVPLYPWSYPNDVIKAGIPPFRTVKLTRIHLEEDAAKITHHANYSLIDYNRAGSALM
                     EIVSEPDIDTPEEAYAYLKSLQQILNYGDISDADMEKGQMRCDVNISLRPHGQKELGAK
                     VEMKNINSMSAVRRALHYEIQRQAEELDMGIPQIQSTRRWDDERGESVVMRTKEDAHDY
                     RYFPCPDLVPVRTAPLVEKVRGQIPELPQERQKRFMEEYGLSEYDANVLVGDLELARFF
                     EEAARGTASGKKIANWVINNISAVLNEKGMRPSECPVKPGAIRELIAIIDDGTVSNNQA
                     KDVFAKMWDEPALAAAQAAKLLGFEKADSSFLDGIVREVISANPDKVAEIQGGNEKLLN
                     WLTGQVMKAAKGKANPKIVTEALKKALSME"
     CDS             complement(11176..12942)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.6e-34, bitscore:
                     108.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPLEVGWCLICMYRVADQIVEILEKAGVKRIYGIVGDSLNPVTD
                     ALRRRKTIEWIHVRHEEVAAFAASAEAQLSGNLAVCCGSSGPGNLHLINGLFDAHRNHA
                     PVLAIAFHIPQSQVGMEYFQATHPEQLFKECSAYAELVSEASQAPSILMSAIQHAWARR
                     DVGVVVLPGDIADAPAEMKNLVHPPSYTRENVVPEHESVSLLARMLDDHRRITFFCGAG
                     CAGAEDKVVRLAHRLKAPIAYTWRGKDHFEHDNPLGIGMTGLLGWGDAYKAMHESDMLV
                     LWGTDFPYFNFIPTKPEIVQIDRRGEVLGRRCRLDLGICGDVSVTAEALLNMVQEKTDS
                     GHLDAALKRHARDVKEMNAYMEGNDKESPIRPEQLTTALNRHAASDAVFTVDTGTPCIW
                     SARFLCATPGRRTLASFNHGSMANAMPMAIGAQMEYPERQVIALCGDGGLSMLLGDLIT
                     IVQYRLPVKIVVYNNDCLDFIQLEMQAAGLIPWQINLNNPSFAAVADAVGIKGFLLDKS
                     SQVDQMVDMFLNYPGAALLDAHVDRDALALPPYISMGQAADFSLAMMKQTLAGEVKQVW
                     NTLAGNRKLFKP"
     CDS             complement(13071..13820)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MKKTLALMAIAACCSVPALASPGSLEPSAGTSYVAGTATTTEGIA
                     LGKDMTFGSLSQSALPGSSIPYGGNFYASNYTISLWLDTSSLTEGTQTTLFGYYGTNVG
                     QSYGTNALYLTSDAKLGMGDGNLNTSTGSFSQNRGDVSEASVVLGGGLLNVTLAVTGAD
                     QSQSVDVYVNGSLLDTLSYNGNMNGNRSDIQSWINPNLTWGEIQWTDTKLSAEQIAGFA
                     GLQVPEPASASLGILGLAVLMMRRRRS"
     CDS             13976..14107
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MNIKNKTQNRFFVEVLKLLYRNSNPFSQNRKNCNNSFIIEMLD"
     CDS             14469..16811
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MTSKLGPVAKAGNELFIINLQDGRSIKSSELKAGNVKFVSLQPNP
                     KAFRLADRFPGKAVSATFQALNGTLRISWRAVLRDHSHYLRQELHLASMKPVQMKNIVA
                     MQYDLAEGKAGAPSVSGNARGALIVNDLAFTALETPMGINTVGGAGNMEGGETAIWNAD
                     KWSTASWTGNFNVPQELKKQYGEQVSSAEGPVSIDGKGACTITFQYKGGDKGNNKLNLA
                     GVQLLSSRGAVLDSDFHNGSTGDSNAGNTYTVQVPSRGNYILRYWAQTKSEPIASKGEI
                     TFSLPVRTLEEKQEPQADESRLAQGLWSRKTTLQPGEIWDVSSVLGIFAPGQKRRSFLA
                     YMERERVMPYRPFIHYNSWYELNINRNNDSDPAKRMTEEQCLAVLKDWQEQFFQKRGMS
                     IDAFVWDDGWDEFNSLWDFHKMFPQGFKRIDAAAGRQKAGIGTWLGPVGGYGASKGKRL
                     AYWNVKHPDNKIGNFQLSNKEYFDAFVGRCSQMVKDYNMKYFKFDGISTHFHAKGPGNE
                     EDAEGIIRVLNALRKKKGDLYINCTVGTWASPFWFRYADSVWRQENDFGTIGAGDNRDK
                     WITYRDRLVHEVFVQGSPLMPINSMMTHGLMVTKFGPPACMPRDPENVKKELRCATACG
                     TSLQELYVDRDLMSANGGVLWDELAKGIKWIRRNADVLDDVHWVGGNPWNKETNEGAVY
                     GWAAWNKNKATLALRNSSDQEKSLTGTLRSILDIPANVKGSITFKDSYDDQRTLDGFSG
                     SSVDIDKEISFTLKPFEVLVYEGGKVK"
     CDS             complement(16922..17575)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MWNDLSHGFSVLADALAFLSRSWGFWVCAGSVAGLAAVYAWWRKR
                     LALWAFVLAFLSLLAVVGLACRQAVCQKVFLWIHEPDVQALSGKYEVEPSPRERRFFRP
                     PELKRFFQVSSSTLLLNEDGTCEISSFPRPEAWGRWIARPEEREDLSVLEEDLVSSCRG
                     TWSLVKKGGYYGVSIAYSPGRSLMLYLGGEGAECLVMPVNPADPLEAVTFEKTF"
     CDS             17742..20498
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MKSAAHHQGLSEQQVLENRTRYGINILTPPEKEPLWKQFLEKFSD
                     PIIKILLVALLLSVGVAFYQFFTGTESASVFLEPAGILAAILLATCVGFAFEVSANKKF
                     EILNQVNDDTMVQVIRGGNICELPRRDVVVGDIVILNTGEEIPADGVLLEAVSLQVNES
                     TLTGEPLIGKTTNEAEFKKDATYPSNHVLKGTTVADGHGVMEVTSVGDKTEYGKVYEGS
                     QIDNKVQTPLNRQLSRLGDLITWASYAIAALIVIGRLTLYFSHLPGPVEWLSAGTYILN
                     TVMIAVTVIVVTVPEGLPMSVTLSLALSMKSMLANNNLVRKMHACETMGAATVICTDKT
                     GTLTRNQMNVYKADFYGLGNAVPTEDEPGNLIREGIAVNSTAFLDYADPEHIRALGNPT
                     EGALLLWLHGLGVNYLDLRENARVLEQLTFSTERKYMATVAESPLLGKKVLYVKGAPEI
                     VLGLCSTVLTPEGQVPAADMRPAIEEQLLAYQNQAMRTLGFAYRILEDDAPVFEDGRII
                     RKDLVYLGITAISDPVRDDVPQAVKDCMDAGIRIKIVTGDTPGTAREIGRQIGLWTEED
                     SPDRLMTGVEFEQTPDAELLDRVMDLKIMCRARPMDKERLVKLLQKKDQVVAVTGDGTN
                     DAPALNAAQVGLSMGDGTTVAKEASAITILDNSFMSISRAVMWGRSLYRNIQRFIVFQM
                     TINVAACLIVLIGAFLGTESPLTVTQMLWVNLIMDTFAALALASLPPDERVMQDPPRKT
                     TDHIITRPMGRNILGVGILFVAFLFGLLQYFKHADITSLTQFSLSGYFRSYLDFSAPEH
                     ELTGYELSLFFTIFVLLQFWNMFNAKAFNTHQSAFARMGASIGGFGLVALLILAGQYLI
                     VTFGGKMFNVVPLSWTDWGLIFAGTSLVLWFGELARAFTPDKSGARS"
     CDS             20597..21754
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_17"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 2.3e-09,
                     bitscore: 28.8, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTRLTGSISSPAVFLFLLSLFFAGCKKTEQVPHETPTLIYEHP
                     VTMDIPVTGSWVGHLDGVDNASIVPQITGYLQTQNYANGAIVKKGEVLFRIDDSTFRDQ
                     VSKAKATLAQAQAQLQQLNYDAEIYRPLAAENAISKQKYEDTRLSALAAEAQVQQAAAA
                     LALAEKNLSYTVLYAPFDGIAGISRTNIGDLVSPESGPLAVVSSVNPIRVNFAVTQQEW
                     IQQAGKNGNEGVQTGSKLDITLKDGTKYPEQATVVAIDRAFNPQTGTIRVQANLPNADY
                     LLRPGMFIIATARLATVKNALTVPAKSLLSTQGRFFVIVLDGSNHPSIIPVQAGTQLGD
                     RQQVIPLKPDSLTPQSKVVVDGLLQAEAASRNPAARLKAVPASNQ"
ORIGIN
        1 gcggcttccg cacccgtggc cgctccggcc ccggctcccg cacctgctcc ggctccggcc
       61 gccgccggcg caggagacgt tcccagcccg cttgccggga aggtcgtctc tctggacgtg
      121 gcagcaggca cccccgtgaa ggccggtgac cagattctga cgctggaagc catgaagatg
      181 aacaccatca tctacgctcc cgcctccggc acgctcaccg ctttctgcgt gaacccgggc
      241 gacacggttc aggaaggaca ggcactggcc aaaattggtt aatcccggcg gcggcagccc
      301 ggaaacgcca acagtcccgg gctccggctc agataataaa ccgctacaaa aatattccct
      361 atgagtcttt ttgattcatt aatcaccttt ttacagggga tgggcgtctt ctccctatca
      421 tggcagatgg tagggatgtg gggcattgcc attctcctcc tgtatctggg tgtagccaag
      481 caatacgaac cgctcctgat ggttcccatt gctttcggcg ccctcattgc caacattccg
      541 gataacggaa tgctcatcac ccagctgaac cagcaggtca tctcctccaa tgaacagggg
      601 gaagtaaccg ccacgtctct gaacaacgtg gggtacctgc gcgttcacgt ggctccgctt
      661 cagcaggctc cctccaaggt gccggccaac ctgaccacgc ctgaatcccg ttcccagtat
      721 caggaaatca tgcagcagcc catgcaggtt taccccggca gccagctgac tgtttccaag
      781 atcaagtccg tgcgggaatc ccaggaaaaa gcaaaagctg acgcggcccg tctgggcgac
      841 gacagcctga cggtggaccc caacctgaag gatttccaga acgtgacgga agacaacggc
      901 aatgaaccgg tctttctgct cacgaacgga gaagggacca ccgtcgtccg ccagcagggc
      961 gtcaattact ttgacaccag cggcaaccgg attccggtgg atctgaaaac ccagaagctg
     1021 gagcccctgg tggtttcagc cgcaggcaaa tacgtggccg taggccagca tacccaggaa
     1081 ctgctggtca cctccatcca cgggggcctg tatgactgga tcgggctggg catcaaggct
     1141 gaaattttcc cgcccatcat ctttctggga gtaggagccc tgacggactt cggcccgctg
     1201 cttgccgctc cgcgcaccct gcttctgggc gcagcggccc aggtgggcgt agccgccacg
     1261 ttcttcatgg ccctgttcat ggggttcacc ccgaatgaat ccgcgtccat cggcatcatt
     1321 ggcggcgctg acggccccac ctccatcttc ctgacgatga agctggctcc gcacctgctg
     1381 ggcgccgtgg ccgtggccgc atacacgtac atgtccctgg ttccgctgat acagccgccc
     1441 atcatggcgt tgctgacgac caagaaggaa cgcctcatcc gcatgaaatc cctgcgaacg
     1501 gtcagcaaga gcgaaaaact gttcttcgcc gtgctggtaa ccattgtcac cattttgctg
     1561 attccggacg catccccgct gatcggcatg ctgatgcttg gcaacttcct gcgcgaatgc
     1621 aaggtgacgg aacgcctggt tcaggcctcc cagaatgaaa tcatcaacat cgtcaccatc
     1681 ttcctgggaa cctccgtggg gctcacgatg cagggcgacc gcttcctgca gtcggaaacg
     1741 ctgctgatca ttcttctggg tatcgtcgcc ttcggcgtgg caacagcggg cggagtgatt
     1801 gccgccaaga ttatgaacct catctggcgc aagaatccgg tcaaccccct gatcgggtcc
     1861 gcaggcgtct ccgccgtccc gatggcagcc cgcgtctccc acaatgtggg ccagaagtac
     1921 gacccctcca actacctgct catgcacgcc atgggtccga acgttgcagg cgtgatcggc
     1981 accgcagtca tcgcgggtta ctacatcgcc actctggcga aataaccaga attgaaaatt
     2041 actcccggcc tcggcccgtc ccatgaattc cgcagcctca ttttccaccc ctccggagga
     2101 ggaaggacca tgcggcgact ggacttatca tgaatgggcc gaggcttttt ccaccaatga
     2161 tctggcccga gccctccccc cggggcatat tgccgtctgc cgcgttcaga caggaggccg
     2221 cggcaggttc aaccgcaaat ggatagggga ggaaggcggc ctgtgggcat ccttcaccgt
     2281 ccccctgtcc gctcctgagg atacagcggc cggcgtgcac tggggccatt tgcccctggt
     2341 tgcggggctg gccctgttca acatgctccg cggcatgggg ctggattccg tgcgcctgcg
     2401 ctggccgaac gacctgctgg cgggcaaatc caaactggcg ggaatactgg tggaacgccc
     2461 ggcggagaac atggccgtca tcggcatcgg catcaatgtt ttcaatgatg tatcctccat
     2521 cgccggggaa atcaaggacc ctccggcaag gctggcggat cttgttcggg actgcccttc
     2581 cctgcacgcc gtcatggctt ccctgggcag tcatttgaac caggttcttt ccgtcttttc
     2641 ccacggcggc gtccccgccc ttcaggaggg gctgtcccgg gcatgggccg gagaaaggcc
     2701 ggtttccatt cttacggatg acgaaaccgt ccggggcatt tttacaggga ttgacgatca
     2761 gggcaatcct gtgctatccc ttccggccgg caccgtccgc accattccgg cgcacctgat
     2821 caacaggctc ctcgaagaat gagcctgccg ctccgttttt acacggggtt tctttctttt
     2881 ttcatccaac aaaaatcact gacatgagtt acaaggtact gacaccagaa gaagcagcaa
     2941 gcctgatcaa gcatggccac catattgggc tgagcggatt cacgcccgcc ggaacggcca
     3001 aggccgttac ggctgcgctg gcaaaaatcg cagaagcgga acatgagaag gggaaccctt
     3061 tccaggtgag cgtcttcacc ggtgcttcca ctggcgattc ctgcgacggg atcctttccc
     3121 gggccaaggc aatccgctac cgcgctccct acaccaccaa cgttgatttc cgcaaggcgg
     3181 tgaacaacgg ggaaatcgcc tataatgaca tccatttatc ccagatggcc caggaagtgc
     3241 gctacgggtt catgggcaac gtggacatcg ccattattga agcctgtgaa gtcacggccg
     3301 acggcaaaat ttacctgacg gccgcgggcg ggatcgctcc caccatctgc cgcctggcag
     3361 acaaaattat cgtggaatta aacgccgccc acagcaagag cgccatgggc ctgcacgacg
     3421 tttacgaacc cctggatcct ccctaccgcc gcgaaatctc catcttcaaa cccagcgacc
     3481 gcatcggcaa gccgtacatc caggttgacc cgaaaaagat tgtgggcgtt gtggaaacca
     3541 actggccgga tgaagcccgt tccttcgccg cagcggatcc cctgaccgat aaaatcgggc
     3601 agaacgtggc cgatttcctg gctgccgaca tgaaacgggg catcattccc tccacgttcc
     3661 tgcctctcca gtccggcgta ggaaacatcg caaacgcggt gctgggcgcc ctgggccgcg
     3721 acaagacgat tcccgcgttc gagatgtaca cggaagtcat ccagaattcc gtcatcggcc
     3781 tgattcggga gggccgcgtg aaattcggca gcgcctgctc cctgaccgtg acgaacgact
     3841 gcctggaagg catttacagg gatatggact ttttccgcga caaactggtg ctccgtccct
     3901 cggaaatatc caacagcccg gaagttatcc gccgtctcgg cgtcatctcc atcaacaccg
     3961 ccattgaagc cgacatttac gggaacgtca actccacgca cattggcggc acgaagatga
     4021 tgaacggcat cggcgggtcc ggcgacttca cgcgcaacgc ctacatctcc attttcacct
     4081 gcccgtccgt tgccaaggac ggcaagatca gcgccatcgt ccccatggtt tcccaccatg
     4141 accatacgga acatgacgtc aatatcatta ttaccgagca gggggtcgcg gacctgcgcg
     4201 gcaagagccc gaaagaacgg gcccagacca ttattgaaaa ctgcgtccac ccggattaca
     4261 aaaacatcct ctgggattac ctgaagctgt ccgacggcaa agcccagaca ccgcaatcca
     4321 tcagggccgc tttgggcatg cacgccgaac tggccagaag cggagacatg aagaatgtcg
     4381 actgggccca gtataagtaa ttccgcatgc cgtcattcgc attggcatcc atgaattcac
     4441 gttaacccct caggaccgct tccgcaaagg gagcggtcct tttccttttt cccatcccct
     4501 ctactctctt ctcttcgcca tgaactggat gatttacccg gcagccaggg ctttcatcaa
     4561 agtctgctcc gttcttttcg gcacgggcgc agcagcggca gtcctcatcc atctgttcat
     4621 gccttttttc ctccgctctc cccggacagc cgcgcccttc ctgcttttgg gaacaggggc
     4681 ggaactgctc tccatccttt ccctgtcctt cctcatgttc tggggcgtca gagttctgct
     4741 ggcctcccgc ggaagcagaa taacaagaaa tctgagcatg ctggccttcc tgcccgccct
     4801 gtacgccctc ctcattccgt ttgcgggcat gcccgtccca tcgcaatata cggaaatgga
     4861 cagggtttgg gaggccgtcc tccttctgtc ggccgtcact tctttctttt ccttccctta
     4921 tacggcggga tacggtgccg caggcaggag attattcctg gcctggggca tcgcagcggc
     4981 aggctgcggt ttgcagagcg ccctgttttt tcttgccgtc ctgttgcgtc agttcctgtc
     5041 caccgcagtt ccctccctgg cagcgcctgt tgcatggctg gccgttcttc tgtcctgcgg
     5101 cctggaaatc atgctggcgg ccctttccgc tattctggcg cagcgcctgt ttaaagaggt
     5161 catgtccata gcatccatgc cggaaccgat tgatccttcc atgccgggca accgtccctg
     5221 actttcctcc cctccgtttt taccggcctg ccggaagagc accctcattc cccggcatga
     5281 aaggctttta cggctttgcg caaaaagccg tccggaaatt tccgccggtg gaacggaatc
     5341 cgtatggaaa gcaacccgcc ccaccccgga aagccgcggg ttcgcaggcc ccccctcccg
     5401 tttccacgcc gacggcagac agccctattt caccaattca tccagataac ggccataacc
     5461 gttattattc atggctccgg cctgggagcg cagcgtttcc tgggaaatcc agccgttatt
     5521 aaaggctatc tcctccaggc aggctacctt gaacccctgg tgatgctcca gagtacgaac
     5581 gaacatggaa gcctccagaa gggtatcgtg cgtgcccgta tccagccacg tatagccgcg
     5641 cgccagtttt tccacgcgca acaggccctg cttcaggtat tcctgattca cagaggtgat
     5701 ttccaactcg ccgcgggaag acttgggaat ccgtttggct atctccacca cccggttgtc
     5761 gtaaaaatag aggcccgtca ccgcaatatc cgatttgggc ctgggcggtt tttcctcaat
     5821 ggaaaccgcc ttcccctcct cattgaattc cactaccccg aaacgctgcg ggtcatgcac
     5881 ctggtaaccg aaaatggtcg ctccgctcgt cagttcggcg gccctcctca gcttctccgt
     5941 caggccgcgc ccgtaaaaaa tattgtcccc cagcaccagg gcaacggaat cctttcctat
     6001 gaactcctct ccaataataa aagcctgagc cagcccctcc ggcctgggtt gttccctgta
     6061 tttaaaggaa acgccgaacc tgctgccgtc ccccagcaaa tcccggtaca ggggcagatc
     6121 ccggggcgtg gaaataacaa ggatttcccg tattccggcc agcatcagca cggagatggg
     6181 ataataaacc atcggcttat cataaacggg cagcaattgc ttgctgacgg aaagcgtaac
     6241 gggatgcaga cgcgtgccgc ttcccccggc cagaacaata cccttcatat caaattccta
     6301 gccattggtt ccaagacgtt ccaggcggta ttccccggac aggatgcccc gccaccattc
     6361 ctcatggtcc agataccact gaatggtctt tctgaatccg gaagaatggt cctggcgcgg
     6421 agtccacccc aattccctcc gtattttgga agcgtcaatc gcatagcgca ggtcatggcc
     6481 cggcctgtcc tgcacaaagg agatttgctc ccggtagctc cggccgtccg gacggggccg
     6541 cagttcatcc agatgggaac acagcagttc caccagctcc agattggttt tctcgttatt
     6601 gccgccgatg ttgtacgttt cccccggttt tccgcaggaa acgaccgtca acagcgcctc
     6661 gcagtgatcc cccacataca gccagtcccg cacgttttcc cccttgccgt atacaggaat
     6721 gggttccccg cccagcgctt tcaggataac gacgggtatc agcttttccg ggaactggta
     6781 agggccgtaa ttgttggaac agttggtgat cagcacgggc agcccgtacg tatcgtgcca
     6841 ggcgcgcacc aggtggtcgc tggaggcctt gctggcggaa tacggggaat gggggcgata
     6901 cggcgtggac tccgtgaaca ggccttcctt tcccagggag ccgtacactt catccgtgga
     6961 aatgtggtgg aagcggaaac gctccttttt ctctccctcc agggaacggt aatattccag
     7021 ggcggcctga agcatggaaa aagtgcccat gacgttggtg gtcataaaat ttcccggatc
     7081 gtcaatggaa cggtccacat gggattccgc cgccaggtgc atcacccagt ccggagcgta
     7141 ctcccgcaaa gtgcgccgca tcagggaagc gtcccggacg tcggcgtgca gaaagcggta
     7201 tgccggagaa tccgccgagc cgtccagtga atggatgttg ccggcatagg tcagagcgtc
     7261 aatattcagg acttcatggc cgcgctccag cagcagcctg accagattgg agccgatgaa
     7321 tccggcgccg cccgtaacga taactttcat agcactgttt tcagggaaag atgcggcgcc
     7381 atcatacagc agcggcgttt tttttcaaaa caaatccgcc catgccgcgg gaacgtggcg
     7441 gcataggcgg gaaaaagcgg gttccgtaac cgctgagacg gctagcagct cagctcccgg
     7501 caaaggttga tgatatcctg gttcacggag tactgctgcc cggctacgga atccagggag
     7561 gcatagccgt actggccgtc atgatacacc atgatctggt tgatgtcccc gttgttcaga
     7621 gcttccacgg cgcgggtggc aaaacgggtg cccatcaggc ggtcacgggc ggtgggggaa
     7681 ccgccgcgct gcacatggcc cagcacggtc aggcgggtat ccatgccggc gcgttccgtc
     7741 agccagcggg tcaggtactg cgccacgcgg gtgccttccg ccaccacggc aatgatgcag
     7801 cttccttcct cattgatgac aggctggagg cgcttgtaaa tggattccag atcatacgga
     7861 atttcaggga caatgcagat atccgccgcg ctgcaaagag cggtggtcat cgccagatag
     7921 ccgcagtccc ggcccatcgt ttcaatcacg aaagcgcggt gatgggaacg ggccgtatca
     7981 cgaacggaat caatgcaatc cagaatcacg ttctgggccg tatccacgcc caggcagtag
     8041 tccgttccgg caatgtcgtt gtcaatcgta gccggaatac cggcaaaagg cacttcaaaa
     8101 tcattgaaaa agtcgttcag ggcgcggaag gaaccgtccc cgcccatgat gatgagcttg
     8161 tcgatgttgc gttccttcag atgttcgtag gcctgcttgc ggaattcgta gtcgaaaaag
     8221 cgcttggatc gtgaggaacg gaggagagtt ccgcccctgt agatcatatc gttggtcagt
     8281 tcccgggtgg cttccttgat ttttccatcg atcagccctt ccaagccgtc ataaacaacg
     8341 tacgggttca tcccaagctg gcgggcatga tccactgccg ccttgatcgc cgggttcatt
     8401 ccggcggcat caccgccaga tgtcataatg gctattccac tcataagtaa taaggttaac
     8461 ttgtccgggg ggaaatgtta ccgggcggaa caaataatgc aagcgcggag tttttactgg
     8521 cgcaataaac ggcaacactt catgatgcgg aggcatgaac gacactgcag cagccattct
     8581 gaaagccacg gccgccctcc gggacggcac ggagaagctc cggttcgaat ccccggtcca
     8641 tgttacctac aaccctctca cctatgcatg ggggccgcat gaacagtatg tgcgcaccta
     8701 cggaaacggg gaaaagagcc atctgttcct gggcatgaat cccggcccct tcggcatggc
     8761 ccagacaggc gtccccttcg gggaagtgga cgccgtcgtc aactggctgc acattcgcgg
     8821 agaagtcggg cggccggaac atacccaccc caaacgtccc gtggagggtt tcggctgccc
     8881 caggtcggaa gtcagcggcc gccgcctctg gggacttttc gcggaagctt tcggaactgc
     8941 ggaaaacttc ttccgtcaca attacgtggc caattactgt ccgctgatct ggatgggagc
     9001 caccggagcc aacattacgc cggacaaact gccggcggaa cagcgcgccg ccgtggacgc
     9061 agtatgcatg gaacacctgc tttccctcat caccatcctg aatccccaca cgctggtggg
     9121 tgtgggtgcc tacgccacgc agaagctgcg ggacgccgcc tcccggctcc ccggcaaaag
     9181 cttcaccatc ggcacgttgc tccacccaag ccccgccagc cccatcgcca acaagctctg
     9241 gccggaacac cccatccagc agcttaagga actgggcatt ttataaaaag agcggaggag
     9301 gtagagtgga aagctccgtg acatggaagg aatcaccaga gcgacaggcc ggaaatcggc
     9361 agttcatctt gttctcctcc aaatctacat cgttttgaag gaatatccgg ccccctttac
     9421 tggcttgatt tgcccaggga cacagccttc ctgacggaag aaaagcacgc cggcatctac
     9481 cgggacagag aagaacttaa acgcctcccc acttccacca caaaaatcag cctccctcca
     9541 aatcaatcat cattcttaga ctgaaaaccc tccgctctcc cccgcaggcc tttttactgg
     9601 acagggggaa aagggttccg tacagtttcc gcgatcttca agcgttccga atttatggca
     9661 atttcagatt acatcgtgac cattggcctg gaagtccact gccagatcaa gacaaagagc
     9721 aaaatgttct gctcctgcga gaccggcttt ggctttgaac ccaatacgcg cgtgtgcccc
     9781 acctgcctgg ggctgccggg cgccctgccc gtcctgaatg agttcgccat tgaacgcacg
     9841 ctgctgaccg gcctgatgct gggatgctcc agcccggaga tttcccaatg ggaccgcaaa
     9901 aattatttct atccggacat ggctaaaaat taccagacct cccagctgga tcttccgctg
     9961 tgcctgggag gggaagtgcc cctgtacccc tggtcctatc cgaatgacgt gatcaaagcc
    10021 ggcatccccc ctttccgcac cgtgaagctg acccgcatcc atctggaaga agacgcggcg
    10081 aagattaccc atcatgccaa ttattccctg atcgactaca accgcgcggg gtccgccctg
    10141 atggaaatcg tttccgagcc ggacatcgac accccggaag aagcctacgc ctacctcaag
    10201 tccctccagc agattttgaa ttacggggat atctccgacg cggacatgga aaagggccag
    10261 atgcggtgcg atgtgaatat ttccctgcgt ccccacgggc agaaggaatt gggcgccaag
    10321 gtggaaatga agaacatcaa ctccatgtcc gccgtccgca gagcccttca ttatgaaatc
    10381 cagcgccagg cggaagaact ggacatgggc attcctcaaa tccagtccac ccgccgctgg
    10441 gacgacgaac gcggagaaag cgtcgtcatg cgaaccaagg aagacgcgca cgattaccgt
    10501 tatttcccct gtccggatct ggttcccgta cgcacggccc cgctggtgga gaaagtgcgc
    10561 gggcagattc ccgaactgcc tcaggaacgg cagaaacgct tcatggaaga atacggcctg
    10621 agcgagtacg acgccaacgt gctggtggga gacctggaac tggcacgctt ttttgaagag
    10681 gcggcgcggg gaaccgccag cggcaaaaaa atcgccaact gggtgattaa caacatttcc
    10741 gccgtgctga atgaaaaagg catgcgcccg tctgaatgcc cggtgaaacc cggcgccatc
    10801 cgggagctga tcgccattat tgacgacggc accgtttcca acaaccaggc caaggacgta
    10861 ttcgccaaaa tgtgggatga gccggccctc gccgcagcgc aggccgccaa gctgctgggc
    10921 tttgaaaagg cggattcctc ttttctggac ggcatcgtgc gggaagtcat ttccgccaat
    10981 ccggacaagg tggcggaaat acaggggggc aatgaaaagc tcctgaactg gcttaccggc
    11041 caggtcatga aggccgccaa aggcaaagcc aacccgaaaa tcgtgacgga agcgctgaaa
    11101 aaagcccttt ccatggagtg accataaaca aagagccgct tcccttgccg atgccggctc
    11161 cttgcccgca gggcatcacg gtttgaacag cttcctgttt ccggccaggg tgttccatac
    11221 ctgcttcact tccccggcca gcgtctgctt catcatggca agggaaaagt ccgccgcctg
    11281 gcccatactg atgtagggag gcagggcaag ggcgtccctg tccacatgcg cgtccagcag
    11341 agcggcgccc ggataattca ggaacatgtc caccatctgg tccacctggc tggatttgtc
    11401 caataaaaac cccttgatgc cgacggcatc cgccacggcg gcaaaagagg ggttgttcag
    11461 gttgatctgc cacggaatca gcccggccgc ctgcatttcc aattggatga aatccagaca
    11521 gtcattgtta tacaccacga ttttcaccgg cagcctgtac tggacaatcg tgatgagatc
    11581 ccccagcagc atggacaggc cgccatctcc gcacagggca attacctgcc gttcggggta
    11641 ttccatctgc gccccaatag ccatcggcat ggcattggcc atggagccat gattgaagga
    11701 agccagcgtc ctccttcccg gcgtggcgca caggaacctg gcgctccaga tacagggggt
    11761 gccggtatct accgtaaata cggcgtcgga tgccgcatgc ctgttcaggg cggtcgtgag
    11821 ctgttccggc cggatgggag actccttgtc atttccttcc atataggcgt tcatctcctt
    11881 cacgtccctg gcgtggcgtt tcagggcggc atccaaatgc ccggaatccg tcttttcctg
    11941 caccatgttc agcagagctt ccgccgtgac ggaaacatcc ccgcaaatac ccaggtccag
    12001 gcggcagcgg cggcccagca cttcaccgcg cctgtcaatc tgcacgattt caggtttggt
    12061 gggaatgaaa ttgaaatagg ggaaatccgt cccccacaac acgagcatgt cgctttcatg
    12121 catggccttg taggcatctc cccatcccag cagccccgtc atgccgatgc ccaggggatt
    12181 gtcatgttca aaatgatcct ttcccctcca tgtgtaggca atcggagctt tcaggcggtg
    12241 cgcgagccgg acgaccttgt cttccgctcc cgcgcagccg gcgccgcaga agaaagtaat
    12301 gcggcggtgg tcgtcaagca tccgtgccag aagggatacg gattcatgct caggaacaac
    12361 attctcccgc gtgtaggaag gaggatgcac cagattcttc atctccgcag gggcgtccgc
    12421 aatgtctccg ggcaagacga cgacgcctac gtcgcgcctg gcccacgcgt gctgaatggc
    12481 ggacatcaaa atggacgggg cctgggaagc ttccgaaacc agttccgcat atgcactgca
    12541 ttccttgaaa agctgttccg gatgcgtggc ctggaaatat tccatgccta cctggctctg
    12601 cgggatgtgg aaagcaatgg ccagcaccgg ggcatggttc cggtgggcgt caaacaggcc
    12661 gttgatcaaa tggaggttcc cggggccgct gctgccgcag catacagcca gattcccgct
    12721 cagctgggct tccgcgctcg cggcaaaagc cgccacttcc tcatgccgca catgaatcca
    12781 ttcaatggtc ttcctcctcc tcaaagcgtc cgtaacgggg ttcaggctat cccccacaat
    12841 gccgtaaatc cgcttaactc ccgccttctc caaaatttca acaatctgat cggctaccct
    12901 gtacatgcag attagacacc agccaacctc caacggattc attcttatgt gtcatcccct
    12961 ccatcttttc cgcaccggaa aaaatgcctg aggatttccc ctgatatcat aaagccgccg
    13021 ccttttcagg cagcggccta tgaatttacc agttctctgg tggaaaaccg tcaggaacgg
    13081 cggcggcgca tcatcagaac ggccaggccc aggattccca gagaagccga ggccggttcc
    13141 ggaacctgaa ggccggcaaa accggcaatc tgttccgcgg aaagttttgt atccgtccac
    13201 tgaatttcac cccatgtaag attgggatta atccagcttt ggatatcaga gcgatttccg
    13261 ttcatgttgc cgttgtagga caacgtgtca agcaaggaac cattcacata gacatccaca
    13321 gactggcttt ggtctgcgcc ggtaacggcc aaagtcacgt taagaagacc tccccccaaa
    13381 acaacggaag cttcagaaac gtctccacgg ttttgggaaa aagagccggt agaagtattc
    13441 aagttcccat ctcccatgcc cagcttggca tctgacgtca gatacaaggc atttgtcccg
    13501 taactttggc ccacattggt gccataatac ccaaacagcg tggtctgggt tccttccgtt
    13561 aaggaagaag tatccagcca gagggagatc gtgtaattgg aagcataaaa attaccgccg
    13621 taaggaatgg aactgccagg aagggcactt tgtgagagac ttccaaacgt catgtctttt
    13681 cccaatgcaa taccttcggt tgtcgtcgcc gtaccggcaa cgtaagacgt tccggccgat
    13741 ggttctaaag agccgggaga cgccaacgcc ggaacggaac aacacgccgc aatggccatt
    13801 aatgctaatg tttttttcat tttctgtgaa tgatggactg agtagcaatc agagagatat
    13861 tccccgccct ctgtatatcg gattcccaat ccgctctttt tctcccccac aggaaagatg
    13921 agaacaagct ttttcaatcc gctaaaaaat ataatataat taccttctat cacttatgaa
    13981 tataaaaaat aaaacgcaga atagattttt tgtggaggtt ctgaagttgc tgtataggaa
    14041 cagcaatccc ttttcgcaaa atagaaaaaa ttgtaataat agtttcataa ttgaaatgtt
    14101 agattgacct cggattggga atccggttgt tttccctcag ccatcaaaaa aatcaacata
    14161 atgttttcat attcaataaa aattaatttt ctttccttcc atttccagaa ccttcttctt
    14221 gaaaacgagc cttccccaaa ttatcctccc gctagctgta atattatttc atcatgaaat
    14281 ttttcaagac aaccattgcc atggcaaccc tgctgggctg cctgcccaca tcccccgcag
    14341 aagtcgcctt tccggggcct gcacccggaa cagccagcgc ggaacaatcc gcttccggct
    14401 atactctttc caataacatc ctgacggcca aatttatcct tcggaacgga agtctttcct
    14461 tcggaggaat gacttccaaa ctgggccccg tcgccaaggc agggaatgaa ttattcatca
    14521 tcaatcttca ggacggacgg agcattaaat cctccgagct gaaagcggga aacgtcaaat
    14581 tcgtctccct tcagcccaac cccaaagcct tcaggctggc tgaccgcttc ccgggaaaag
    14641 ccgtcagcgc aacattccag gctctgaacg gaacccttcg catttcctgg cgcgccgtgc
    14701 tcagggacca ttcccattac ctgaggcagg aactccacct ggcaagtatg aagcccgtcc
    14761 agatgaaaaa catcgtagcg atgcaatatg acctggcaga agggaaagcc ggggcaccct
    14821 ccgtttccgg aaacgccaga ggagcactca tcgtcaatga cctggcgttc accgccctgg
    14881 aaactcccat gggcatcaat accgtgggag gcgccggaaa tatggaaggg ggagaaaccg
    14941 ccatctggaa tgcggacaag tggtccacag cttcatggac cggaaatttc aatgttcccc
    15001 aggaactgaa aaagcagtac ggagaacagg tttccagtgc ggaaggcccg gtttccattg
    15061 acggcaaagg agcatgtacc atcactttcc agtataaggg aggggacaag ggcaacaata
    15121 agctgaacct tgccggcgtg cagctcctct cttccagggg ggccgttctt gactccgatt
    15181 tccacaacgg cagcaccgga gattccaatg ccggcaacac ttacacggta caggttccct
    15241 ccaggggaaa ttacattctg cgctactggg cccagaccaa gagcgaaccg attgccagca
    15301 agggggaaat caccttttcc ctgcccgtgc gcacgctgga ggaaaagcag gaaccccagg
    15361 cggacgaatc ccggctggcc cagggactct ggagccgtaa aaccaccttg cagcccgggg
    15421 aaatatggga cgtatcctcc gttctcggaa tttttgcccc cggccagaaa cgccgctcct
    15481 tcctggccta tatggaacgg gaacgcgtga tgccctaccg ccccttcatc cattataact
    15541 cctggtatga actgaacatc aaccgcaaca atgattcgga ccccgccaag cgcatgacgg
    15601 aagaacaatg cctggccgtc ctgaaagact ggcaggaaca gtttttccag aagcgcggca
    15661 tgtccattga cgccttcgtc tgggacgacg gctgggatga attcaacagc ctgtgggatt
    15721 tccacaaaat gttcccgcag ggcttcaagc gcattgacgc cgccgccggc aggcaaaagg
    15781 ccggcatcgg cacgtggctg ggtccggtgg ggggctacgg agcctccaag ggcaagcgtc
    15841 tcgcttactg gaacgtgaag catccggaca acaagatcgg caatttccag ctctccaaca
    15901 aggaatattt tgacgccttt gtgggccgct gttcccagat ggtgaaggac tacaatatga
    15961 agtacttcaa attcgacggc atcagcaccc acttccatgc caaggggccc ggcaacgagg
    16021 aggatgcgga aggcatcatc cgcgtgctga acgccctgcg caagaaaaag ggggatcttt
    16081 acatcaactg cactgtagga acctgggcat cccccttctg gttccgttat gcggattccg
    16141 tatggaggca ggagaatgac ttcggcacca tcggagcggg cgacaaccgc gacaaatgga
    16201 tcacctaccg cgaccgcctg gtgcatgaag tttttgtgca gggttccccg ctgatgccca
    16261 tcaattccat gatgactcac ggcctgatgg tcactaaatt cggtcctccg gcctgcatgc
    16321 cccgcgatcc ggaaaacgtc aagaaagaac tccgctgcgc cacggcttgc ggcacttccc
    16381 tccaggagct ctacgtggat cgggacctga tgagcgccaa cggcggagtt ctgtgggacg
    16441 aactggccaa ggggatcaag tggatacgcc gcaatgcgga cgttttggac gatgtgcact
    16501 gggtgggcgg caatccgtgg aacaaggaaa ctaacgaagg ggccgtgtac gggtgggccg
    16561 catggaataa aaacaaggcc accctggctc tccgcaattc ctccgaccag gaaaagagcc
    16621 tgaccggaac cctgcgcagc attctggata tccctgcgaa cgtcaagggc tccatcacct
    16681 tcaaggattc ctatgacgac cagcggacgc tggacggctt ctccggcagt tccgtagaca
    16741 ttgataagga aatctccttc acgttgaagc cctttgaggt gctggtgtac gaagggggaa
    16801 aggtcaaata aatcaaccgg cccacacgcc cggtcaaagc cggaacggcg ttggaaaaaa
    16861 catattgggg gaggcgggat tcccgcctcc cttccttgtt cccgtgcggg cagaatccgg
    16921 gtcagaatgt tttttcaaac gtcaccgctt ccagcggatc ggcagggttg accggcatca
    16981 ccaggcattc cgcaccttcc ccgcccaggt acaacatcag gctcctgccg ggggaatagg
    17041 cgatggagac accgtaatat cctccttttt tcaccaggga ccaggttccg cggcaggaag
    17101 aaacgagatc ttcctccagc acggaaaggt cctccctctc ttccggacgg gcaatccacc
    17161 tgccccatgc ctccggacgg ggaaaggaag aaatctcgca cgtcccgtct tcattcagga
    17221 ggagcgtgga agaactgacc tggaaaaaac gcttcaactc cggagggcgg aaaaaccgcc
    17281 tttccctggg agatggttcc acctcatact ttccggaaag ggcctgcaca tccggctcat
    17341 gaatccacag gaaaactttt tgacacaccg cctggcggca cgccagcccc accacggcca
    17401 gcagggaaag gaacgccagg acaaacgccc acagggccag ccgctttctc caccacgcat
    17461 aaacggcggc cagccccgcc acactgcccg cgcaaaccca gaacccccag gaacgggaaa
    17521 ggaaggccag ggcatccgcc agcacggaaa atccatgaga aagatcattc cacataggtg
    17581 ctccagaatc tccggaacat agtcaaagtc aagacaacaa tgccgccctt caaggcacgg
    17641 gcctcaggct gcgccccgat aaaaaactcc cgtcatcact cctgaaaata ttcctccgcg
    17701 cttttctcac aggctccaat caggtaagaa gcatctgaac catgaaaagc gcagcacatc
    17761 atcaggggct ttcggaacag caggttctgg aaaaccggac cagatacggg atcaatatcc
    17821 tgactcctcc ggaaaaggaa cccctgtgga agcaatttct ggagaaattt tcagacccca
    17881 tcatcaaaat tctgctggtg gccctgctcc tgtccgtagg cgtggctttc taccagtttt
    17941 tcaccggaac ggaatcggcc agcgtcttcc tggagcccgc gggcatcctg gcggccatcc
    18001 tgctggccac ctgcgtgggg ttcgccttcg aggtaagcgc caacaagaag tttgaaatcc
    18061 tgaaccaggt caatgacgac accatggtcc aggtcatccg cggcggcaat atctgcgaat
    18121 tgccccgccg ggacgtggtg gtgggcgata tcgtcatcct gaacacaggg gaggagatac
    18181 cggcggacgg cgtcctgctg gaagccgttt ccctccaggt caatgaatcc acactgacgg
    18241 gggaacccct catcggcaaa accacgaatg aagcggaatt caagaaggat gccacctacc
    18301 cctccaacca cgtcctgaaa ggaaccaccg tggcggacgg ccacggcgtc atggaagtga
    18361 cttccgtggg tgacaaaacg gaatacggca aggtttatga aggttcccag atcgacaaca
    18421 aggtgcagac gcccctcaat cgccagcttt ccaggctggg cgatctcatc acctgggcca
    18481 gctacgccat cgccgccctc atcgtcatcg ggcgcctcac cctgtatttt tcccatctgc
    18541 cgggccccgt ggaatggctg agcgcgggaa cctacattct gaataccgtc atgattgccg
    18601 tgaccgtcat cgtagtcacg gtgccggaag ggctgcccat gagcgtcact ctgagcctgg
    18661 cgctgagcat gaagagcatg ctcgccaaca acaacctggt acgcaagatg cacgcctgcg
    18721 agaccatggg ggccgccacc gtcatctgca cggataagac gggcaccctg acgcgcaacc
    18781 agatgaacgt gtacaaggcg gatttttacg ggctggggaa cgccgtcccg acggaagacg
    18841 agccgggcaa cctgatcagg gagggaatcg ccgtcaactc caccgctttc ctggattacg
    18901 cagacccgga acatatcagg gccctgggca atcccacgga aggggcgctc ctcctgtggc
    18961 tgcacgggct gggcgtgaat tacctggacc tgcgggaaaa cgcccgcgtg ctggaacagc
    19021 tcactttctc cacggaacgc aagtacatgg ctaccgtagc ggaatccccc ctgctgggca
    19081 aaaaagtcct ttacgtgaaa ggcgcgccgg aaatcgtgct gggtctctgc tccaccgtcc
    19141 tgactccgga aggccaggta cccgccgcgg acatgcgccc cgccattgag gaacagctcc
    19201 tggcctacca gaaccaggcc atgcgcacgc tgggcttcgc gtaccgcatt ctggaggatg
    19261 acgccccggt gttcgaggac ggccgcatca tccgcaaaga cctggtttac ctgggcatca
    19321 ccgccatttc cgaccccgtc cgggacgatg tgccccaagc cgtgaaggac tgcatggacg
    19381 cgggcatccg catcaagatc gtcacggggg acactcccgg caccgcacgg gaaatcggcc
    19441 gccagatcgg cctgtggacg gaggaggatt ctccggaccg cctgatgacg ggagtggaat
    19501 tcgagcagac tccggacgcg gaactgctgg accgcgtgat ggatctgaaa atcatgtgcc
    19561 gcgccaggcc catggataag gaacggctgg tcaaactgct ccagaagaag gaccaggtag
    19621 tggccgtcac cggggacggc accaacgacg cccccgctct gaacgccgcg caggtggggc
    19681 tttccatggg agacggcacc accgtagcca aggaagccag cgccatcacc attctggaca
    19741 attccttcat gagcatttcc cgcgccgtca tgtgggggcg ttccctgtac aggaatatcc
    19801 agcgcttcat cgtcttccag atgaccatta acgtggcggc ctgcctcatt gtgctcatcg
    19861 gcgcattcct gggcacggaa tcccccctca ccgtcactca gatgctctgg gtaaatctca
    19921 tcatggacac cttcgccgcg ctggcgctgg cctccctgcc gccggacgaa cgcgtgatgc
    19981 aggacccgcc gcgcaaaacc acggaccaca tcatcacccg ccccatgggc cgaaacatcc
    20041 tgggcgtggg catcctgttc gtcgctttcc tgttcggcct gctgcaatat ttcaagcatg
    20101 cggacattac cagcctcacg cagttcagcc tcagcggcta cttccgcagc tacctggatt
    20161 tttccgcccc ggaacatgaa ctgacgggtt atgaactgtc cctgtttttc accattttcg
    20221 tcctgctcca attctggaac atgttcaacg ccaaggcatt caacacgcac cagagcgcct
    20281 ttgcacgcat gggcgccagc attggcggct tcggtctggt agccctgctt atcctggccg
    20341 ggcagtacct catcgtcacc tttggcggaa agatgttcaa cgtggtgccc ctgagctgga
    20401 cggactgggg cctcatcttc gcaggcacct cccttgtcct gtggttcgga gaactggcgc
    20461 gggcattcac tccggataaa tccggcgccc gctcctgaac cgtccggggg aattcccccc
    20521 gcgcatgacg cggacggcga cgccgcccgg aaaaccttct ttcaacaaag gcgcccgcag
    20581 gcgtgtcatt cccagcatgg acttgacacg cctgacgggc tctatctcca gccccgccgt
    20641 tttcctcttc ctgctttccc tcttttttgc cgggtgtaaa aagacggaac aggttccgca
    20701 tgaaacgccc acgcttattt atgaacaccc cgtcaccatg gatattccgg tgacgggcag
    20761 ctgggtgggc cacctggacg gcgtggacaa cgcctccatc gtcccccaga ttacgggcta
    20821 ccttcaaacg cagaattacg ccaatggcgc tattgtgaag aagggggaag tactcttccg
    20881 cattgacgat tccacgttca gggaccaggt atccaaggcc aaagccaccc tggcccaggc
    20941 acaggcccag ctacagcagt tgaattacga cgcggaaatt tacaggcccc tggctgcgga
    21001 gaatgccatt tccaagcaga aatacgagga tacgcgcctg tccgcccttg ccgcggaagc
    21061 acaggtgcag caggcggcgg cggccctggc cctggctgaa aaaaatcttt cgtatacggt
    21121 gctgtacgcg ccttttgacg gaatagccgg catctccagg acaaacatcg gcgacctggt
    21181 cagcccggaa agcggcccgc ttgccgtcgt ctcctccgtc aatcccatcc gcgtcaattt
    21241 cgccgtcacc cagcaggaat ggattcagca ggcgggaaag aacgggaatg aaggcgtcca
    21301 gacgggcagc aagctggaca ttacgctgaa agacggcacc aaatacccgg aacaggccac
    21361 ggtagttgcc attgaccggg cgttcaatcc ccagacaggc accatccgcg tacaggccaa
    21421 ccttcccaat gcggactatc tgctgcgccc cggcatgttc atcatcgcca cggcccggct
    21481 ggccaccgtc aaaaacgcgc tgaccgttcc ggcaaaatcc cttctttcga cacaggggcg
    21541 ctttttcgtg attgttctgg acgggagcaa ccacccttcc atcatccccg tacaggccgg
    21601 gacgcagctt ggagaccggc agcaggttat tcccctgaaa ccggattccc tcacccccca
    21661 aagcaaagtg gtcgtggacg gtcttctcca ggcggaagca gcctccagaa atccggccgc
    21721 ccgcctgaaa gcggtacccg ccagcaacca ataagctcct cccgccatgg ctgatttctt
    21781 catcaagcgc cccatccttt ccatctgcct ctccatcatc attgtcctgc tgggggcctt
    21841 ttccattctg cgcctgccca tctccgagta cccggacatc atccccccct ccatccaggt
    21901 gacggccact tatcccggag cggactgtga aacggtggtc aagtctatcg catcccccat
    21961 cgaacagcaa atgtccggcg tggacggaat gtcctacatg acttccgtca acaccaacaa
    22021 cgggcaaatg agcatgatga tcctttttga aatcggcacg gaagccaaca tggaccaggt
    22081 gctttcctat ctgcgctacg ggcaggccac ctcccagctg ccgtcggaag tcagcgcgct
    22141 gggagtctcc ctgcgcaaga caagcggtct gcccgccctg gtcgtcagcc tgtattcgcc
    22201 ccaggggact tatgacggcc tctggctggc caattacgcc tatatcaata tggtggacgc
    22261 catcaagcgc gtgcccggag taggagacgt gcaggtgttc ggggcaggcc gctacgccat
    22321 gcgcatctgg ctgaacccgg aaaagatggc cgctctgaat attacggcca gggacgtgat
    22381 gctggccgtt caggcccaga acgccgtgaa tcctgcgggc aagataggcg cacagcccgc
    22441 tccgccggac cagcagcttt ccttcaccgt gaaagctcca ggccgcctga ccagcgtgaa
    22501 ggaattcgaa aatatcgtgg tacgcgggca ggacagttcc atcgtaagag tgggagatat
    22561 cgcccgcgtg gaactgggct cggaaaccta cagcctcagt tcttccgtaa acggcatgcc
    22621 cgccgcttcc atcggcattt acgaagcgcc cggaggaaat gccatccagc tggtggacaa
    22681 tatcaaagac ctgctgaagg atacggatat gcctcccggc atggattacc tcgtttccct
    22741 ggattccacg ctggccgtcc gcgccgggat tgaagatatc gtcagcacgc tggtgattgc
    22801 cctgggcctg gtggtgctgg tggttttcat tttcctccag ggctggcgcg gtacgctgat
    22861 tccggccttt gccgttccgg tgtctatcgt gggcgccttc atcgcctttc cattattcgg
    22921 tttttccatc aataccatct gc
//
