LOCUS       gnlProkkaPECMBOJN_119   8561 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PECMBOJN_119.
ACCESSION   gnlProkkaPECMBOJN_119
VERSION     gnlProkkaPECMBOJN_119
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 00:30:24
            Original ID  :: gnl|Prokka|PECMBOJN_119
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8561
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8561
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[395:749]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      396..749
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..8561
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8561
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..388
                     /locus_tag="ctg119_1"
                     /transl_table=11
                     /translation="MEPKTLTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVT
                     DLKSPDVSATEEGKKKVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVL
                     FNKNSTIKVLFDTATGGLIKVDRE"
     CDS             complement(396..749)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_2"
                     /sec_met_domain="PqqD_RRE (E-value: 9e-11, bitscore: 30.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.6e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(769..2160)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102; E-value: 4.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg119_3"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMVAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(2314..2703)
                     /locus_tag="ctg119_4"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             complement(2708..3481)
                     /locus_tag="ctg119_5"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     KSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(3486..4010)
                     /locus_tag="ctg119_6"
                     /transl_table=11
                     /translation="MDWIKKAAFASLLVSLLFLVNSCSMKLGLAPISSIDYTKVKTISI
                     ADFQNRAEYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQYNESVDA
                     SGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLITLMVKDIA
                     EQIFNATVANW"
     CDS             complement(3997..5247)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 379.9; E-value:
                     3.1e-115)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg119_7"
                     /transl_table=11
                     /translation="MTKAEIQQVKLRFGIIGNNEALMRAIDIAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EANGGTIFLDEVGELPLPTQARLLRVLESGEFIKVGSSKVEKTDVRIVAATNVNLTQAI
                     ADGRFREDLYYRLNTVPIQVPPLRERGEDVVLLFRKFASDFAEKYRMPAIQLTEDGKQV
                     LLGYSWPGNVRQLKNITEQISIIETNREINASILKGYLPEQNNMQRLPALFGVKEDKSF
                     GSEREILYQVLFDMRQDVTDLKKLVHEIMAERGTVANPAVATSAYYTPATPAVVPPVTS
                     SVPTIIHPSVKPVTPVDDDFQDTEEYVEESLSLDEVEKEMIRKALEKHHGKRKSAAQDL
                     NISERTLYRKIKEYGLD"
     CDS             complement(5249..6346)
                     /locus_tag="ctg119_8"
                     /transl_table=11
                     /translation="MEDNKIRVGITQGDINGVGYEVILKTFADPVMLELCTPIIYGSPK
                     VAAYHRKSLDLPTNFSIVNSASEAVPNRLSVVNCTDDEVKVEFSKPDVEAGKAALGALE
                     KAIEEYKEGMIDVIVTAPINKHTIQSEEFAFPGHTEYIEQKLGDGEKALMILMKDDFRV
                     ALVTGHIPVKEIAGSITKELIQEKLKIFNRSLKQDFAISAPRIAVLSLNPHAGDGGLLG
                     TEEQEIIIPAINEMAAKGMLCYGPYPADGFMGSDNFTHFDGILAMYHDQGLAPFKALAM
                     DEGVNYTAGLPVIRTSPAHGTAYDIAGKGIASEDSFRQAIYVAIDVFRNRQREKEAHAN
                     PLRKQYYEKRDDSDKLKLDSVEEDL"
     CDS             complement(6352..7407)
                     /locus_tag="ctg119_9"
                     /transl_table=11
                     /translation="MRKHLFYLSMVLVLTLFSACGGGKKGVFTPTSSGRAYEVLVVVEP
                     GLWERPAGRALFDVLDSDVPGLPQSERSFRIMYTAPSNYDATLKLIRNIIIVDVNKDLY
                     TQPKFKYARNVYAAPQSILTIQAPDEASFEKFVEENRQVIIDFFTHAEMNRQISVLKDK
                     HSDYIATKVKSQFDCDVWVPGELTSTKEGENFFWAGTNAATGDQNFVIYSYPYTDKDTF
                     TKEYFVHKRDSVMKVNIPGAREGMYMSTDSLMTDVRPISVQGDYALEARGLWRIKGDFM
                     GGPFVSHVRLDKANQRIIVSEIFIYSPDKMKRNLVRQMEASLYTLKLPGSKQEGTEIPV
                     GVTSKDTTNNK"
     CDS             complement(7478..8518)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg119_10"
                     /sec_met_domain="PF04055 (E-value: 1.7e-17, bitscore: 53.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKRPLLGLTLSELQNVVKNLGMPGFSAKQIASWLYGKKVTSIDE
                     MSNLSLKHRELLKEIYEVGAEAPVDAMRSVDGTVKYLYRAGEGHFVEAVYIPDEDRATL
                     CVSSQVGCKMNCKFCMTGKQGFTANLTSNQIINQINSLPERDKLTNVVMMGMGEPLDNL
                     DEVLKALEIMTASYGYAWSPKRVTLSSVGLKKGLQRFIEESDCHLAISLHSPIPLQRRE
                     LMPAEKAFSITEIVELLRNYDFSKQRRLSFEYIVFKGVNDSLPYAKELLKLLRGLDCRI
                     NLIRFHAIPGVNLEGADMETMTAFRDYLTSHGLFTTIRSSRGEDIFAACGMLSTAKQEE
                     NKEELI"
ORIGIN
        1 gaaagaaccc aagacattaa ccatccggct gacgcctaaa gagatgaaag atgaggtggc
       61 tttccgtttt tcccggaagc tgggagtggt ggccaataat gaccttgccg gtgaaccgta
      121 ttatatcagc gtcaccgacc tcaaaagtcc cgatgtatct gccaccgagg aaggcaaaaa
      181 gaaagtggac ggtgtagcct ataaccttcc gggcaaggca caagtgacat tgatgtataa
      241 caataagaaa ttgtttgacg accaacttcc cattacccaa ttcggcaccg tagaatacct
      301 cgcaccggta ctgttcaaca agaattctac catcaaagtg ctgtttgata cggcaacggg
      361 aggattgata aaagtagata gggaataaag gaattctaat tccggattgt caactggata
      421 aatccatcct tacgcaactg cattacgtag gcggtgaccc ggggaatata attctcttcc
      481 tccccaaagt gcctggcaag tagagagatg atttcgcgca cggtacgatg tccatctatc
      541 agattccaga cagctgtacc gtgttcttcc agcctcacat ggatgtcagg agacatcccc
      601 ttcggcaata aaaaacgacg catccattcg tatttaaacc gtgggtaggc gagtacggcg
      661 cactcacctt cccattcggt tgttatatgt ccacagcgga ccggaacagc gtccaacaga
      721 cttacttttc cttcgggtat ttccatcata cggtatccgc ttttcctatt atttctgaat
      781 attaggctct tccagcttat aaccatactt cttgtctgcc ttcttcagca gtagagccac
      841 tataagggac aagcaggcaa taccggtaaa aatgcacata ggcaccgtat agtcatacat
      901 attcgttcca tctggtttct tgccggatat acaataggca tcaagcaccc accctatcaa
      961 tgtaggaata ccccaaagac cgatattctg gataaagaaa atcaatgcgt atgccgtacc
     1021 caactggctt accgggaata tcttggccac agccggccac atggcagaag gtaccagcga
     1081 gaaagcgata cccaaaatta tcatcagcac aatagctacc agccaatagt ttatatcggg
     1141 aatagcataa atgaaatgca cacatatcag catggccgag cccagcagca tgatagatgc
     1201 ggacttgccc cgcttgtcaa tgaaaccacc aaagaccgga gtcagaatca gcgctcccaa
     1261 tgccggaagt ccggcaaatg taccggccac attctcattg ataccgtatt tgataatcat
     1321 caactcggaa gcaaacttct ggaatgggaa tacacaagag tagaacaata cacacagcaa
     1381 tgctatcagc cagaaaccgg gattgaccag aatattcttc acatccttaa aagagaactt
     1441 ctcttcctca tcttccgtac cggcagcaat ggcagcagct tccatctgtt tgtccagctt
     1501 cttgtccatc actgcaaaga tgaagaaagc aatcataccg cccaacaaca gaaccaaacc
     1561 caacaacacc ggtgtggaaa taccgaaagc gcgggccaaa ggaatggcta cggcataacc
     1621 ggcttgcgaa ccgatacgtg ctaaagcgac ttgtaccccc atagccgtgg caagctcttt
     1681 ccccttaaac cacttggcta tgattttgga aactgtaata ccggcgacct ccgctcctac
     1741 tccaaaaatg gaataaccgg caaaagcaac aaacacaccc gttttatagc caaatatttc
     1801 attgattccg aataaagtcg cgtcggcacc ggcaagtccc gtcattgcat agtattcaag
     1861 tgctgtacca cctaccatca ggatagttgc cagctttccg gtgaaacgga taccaaagcg
     1921 gtcgaggatt aatcctcccc aaatcaacat caggaaaaaa acattcagaa aactataacc
     1981 accggtaaag aatccgaaat cggtactcga ccaagccaag tccgtttcca acattgtctt
     2041 caacggtgct accacgtcgt ttacataata agctaccatc atcgtgaagg caacaatcac
     2101 caatgccccc caacgggtag ccttggaatc attcaattta agtttgagtt gttctgtcat
     2161 tgtactattt ggatttcaat ttattaatca gattgcataa attgctgaca aaggtaaata
     2221 aatacttcat caaaacgaaa aaaggctgac accttttcag tatcaacctt tctcttattt
     2281 ttccaagcgg gagtcatccg caatatcctt atcttattct gctgcagggg cttctgctgc
     2341 aggagcagga gtttcagccg gagttgtagc tgcaggggcc tccgattgcg gagcttctgt
     2401 acctacgggc atgttataag gattagtttt ttcttcttgt tgcgcctgtt ccagaatcac
     2461 atcaccgccc ttgcctgtgg aagaaggaat agtgtaagca gaaacaatac tgaagactac
     2521 catgacagct gccagagtcc aggttgcttt ttccaaaaag tccgtagtct tgcgcacacc
     2581 cataatttgg ttggatgatg aaaagcctga tgccagacca cctcctttag aattttgaat
     2641 caatacaatg aagcacatca gcacagatgc aatcagcatt aagataacta ataataaata
     2701 cattttgtta ttttgattta gcgttaataa tcaatttctc caaaaatctg atttggtctg
     2761 caaagtaagc attttttttt ggataattca aacttaattt tttaataatt tcaagcgcct
     2821 tgtcatatcg gtgctgtttt atatagattt tggctaaagt ttccgtaaaa cagctatcgt
     2881 ccaactcttc cgttaccggc gatactgagg gttcttcctc ttcttcagtc tcttcctcct
     2941 tctctacaag aaactccctt ctcgtatccg aggcatccga agactcactc ttttggataa
     3001 agtcatctat caattcatgc ccgcgcagtt taggcacttc cgactcatct tctgcatcca
     3061 caccgggttc ttcctgcatt aaataggccg tataatccac cgcataatcc agctccgtat
     3121 gctgtgaatg ctcttcggga acagtagcca gaaatgcgtc aatcaaggaa agggtacggt
     3181 ccacactcgg ctctttctcc aaatcgccgg aaaacagcga cgagaccttc cgggatttca
     3241 aagtatagcg gtcaccctct ataaagtaaa acagcacacg acggtctgcc acatacaaca
     3301 cagccttgcg caactccgcg ccaaagttga tgtcgtgcag cagatagagg tttttcagat
     3361 agagcaaacg gagcgactgg aaataaggat agcgtgccac caatgtgcga agctcgtaca
     3421 aagtatccct attcagcgtc tcgggatgct gaatccattg ttgcaaatgg gtaggcgtca
     3481 tgagtttacc agttagctac agttgcattg aaaatctgtt cggcaatgtc tttcaccatc
     3541 aaggttatca gctggtcctg cacttcggtc agcaattttg aggaatcata ggtctggaaa
     3601 gccgagaact gctgttcaaa gtcctcctca tggttcgtgt tattggtgta gcgcacgttg
     3661 acagtcagcg tcaccttcac cttcgaagag tagccgctgg catccaccga ttcattatat
     3721 tgattgtagc cggttatttc tccgtctatt tccaggtctc ctccggaatt caccagttgc
     3781 aggcgagtct gctgaatgaa catatccttc attttctggt taaattctgt tgccagcggt
     3841 gcatatacat actctgcccg gttctggaaa tcggcaatgg aaatcgtttt tacctttgta
     3901 tagtcgatag agcttatcgg agcaagtccc aacttcatac tacatgaatt caccagaaat
     3961 aacaagctta ccaacaagga agcaaatgcc gcttttttaa tccaatccat attcttttat
     4021 ctttctgtat aacgtacgct cagagatatt caaatcctga gccgcactct tacgcttgcc
     4081 gtgatgtttt tcaagcgcct tacgtatcat ttctttctcc acttcatcca gggagagtga
     4141 ctcctccaca tattcttccg tatcctggaa atcatcgtcc accggagtaa ccggctttac
     4201 cgaaggatgt ataatggtgg ggacactgga tgttaccgga ggtaccaccg ccggagtagc
     4261 cggcgtatag taggccgatg tggcaaccgc cggattggct accgttcccc tttcagccat
     4321 aatctcatgc accaactttt tcaagtccgt tacatcctgg cgcatatcaa acagaacctg
     4381 gtagagaatt tcccgttcac tcccaaagct cttgtcctcc ttcactccaa acaaggcagg
     4441 caggcgctgc atattgttct gctcaggcag atagcccttc agtatggatg cattgatttc
     4501 acgattggtc tcaatgatgg atatctgctc ggtgatattc ttcaactggc gcacattacc
     4561 cggccatgag tagcccagca acacttgctt gccgtcttcc gtcagctgaa tggcaggcat
     4621 acggtacttt tctgcaaagt ccgaagcaaa ctttcggaac agcagcacca cgtcttcacc
     4681 gcgttcgcgc aatggaggga cctgaatagg aactgtgttc aaacggtaat acaagtcttc
     4741 acgaaaacgt ccgtcagcaa tggcttgtgt caagtttaca ttggtagcgg caacaatacg
     4801 cacatcggtc ttttccacct tagaagaacc tactttgatg aattcaccgc tctcgagcac
     4861 acgcaacaag cgtgcctggg taggcaaagg caattcgccg acttcatcaa ggaagattgt
     4921 tccgccgttg gcctcaccga aatacccctt ccgttcgccg atagccccgg taaatgcgcc
     4981 cttctcatga ccgaacagtt ccgagtcaat cgtcccttcg ggaatggctc cacagttcac
     5041 ggcaatgtac tgtccatgct tgcgccggct gtactggtgt attatctgcg gaaagctctc
     5101 ctttcccaca ccactctctc cggtaatcag tacagacaag tcggtgggcg ctacctggat
     5161 agcgatatca atggcacgca tcagcgcttc attgttgccg ataatgccga aacgtaattt
     5221 tacttgttgt atttccgctt ttgtcattct acaaatcttc ttctacacta tcgagtttca
     5281 gtttgtcgct atcgtcacgt ttctcgtaat attgcttgcg cagcggattt gcatgtgcct
     5341 ctttctcacg ctggcggtta cggaacacat ctattgccac atagatagcc tgccggaatg
     5401 aatcttcaga ggcgattcct ttcccggcaa tatcgtaggc cgtgccatga gcaggcgaag
     5461 tgcgtatcac cggcaagccg gcagtatagt tcacgccctc gtccatagcc aatgccttga
     5521 acggtgccag cccctggtcg tgatacatgg ccaggatacc atcaaaatgg gtaaagttat
     5581 ctgagcccat aaacccgtct gccggataag gaccatagca aagcataccc ttagcagcca
     5641 tttcgttgat ggccggaatg ataatctcct gctcttcagt tcccagcaat ccgccgtctc
     5701 ctgcatgcgg attcagcgaa agcactgcaa tacgcggtgc gctgatagca aaatcctgct
     5761 tcaaggagcg gttgaatatc ttcagttttt cttgtatcag ttctttggtg atgcttccgg
     5821 ctatctcttt aacgggaata tgtccggtca ccaatgctac ccggaagtca tctttcatca
     5881 gaatcataag ggccttctcg ccatctccca atttttgctc tatatactcc gtatgtccgg
     5941 ggaaggcaaa ctcctccgac tggatggtat gcttgttgat gggagctgtg acaatcacgt
     6001 ctatcattcc ctccttatat tcctcaatgg ctttttccag tgcaccaagt gcagctttac
     6061 cagcttcaac gtcaggttta gagaactcaa cctttacttc atcatccgta cagttcacta
     6121 cactcaagcg attgggaacc gcttcggagg cggagttgac gatactgaag ttggtaggca
     6181 agtccaatga tttacgatga taagctgcca ctttaggcga accgtagata atcggcgtgc
     6241 acaattccag catcaccggg tctgcaaacg tctttaaaat cacttcatac cctacaccat
     6301 taatgtcgcc ttgtgtaatg ccgactctta ttttgttgtc ttccattttt attacttatt
     6361 attagtagta tcttttgagg ttacgcctac cggaatttcc gtaccttcct gcttgctgcc
     6421 gggcagtttc aaggtataga gcgaagcctc catctgacgt accagattac gtttcatttt
     6481 atcaggtgaa taaataaata tttcagatac gataatacgc tgattggcct tgtccaaacg
     6541 tacatgcgat acgaacggac cgcccatgaa gtcacccttt atgcgccaca agccgcgggc
     6601 ctccagtgca tagtctccct gcacactgat ggggcgtaca tcggtcatca gagaatccgt
     6661 cgacatatac atgccttcac gggcaccagg gatattaacc ttcatcacgg aatcgcgttt
     6721 atgaacaaaa tattctttag taaacgtatc cttatccgta taaggataag agtagattac
     6781 aaagttctgg tcgccggtag ctgcattcgt acctgcccag aagaagttct caccctcctt
     6841 ggtagatgtc agttcgcccg gcacccatac atcgcaatcg aactggcttt tcaccttcgt
     6901 tgctatatag tcgctatgct tgtccttcaa tactgaaatc tgacgattca tttccgcatg
     6961 ggtaaagaaa tcgatgatta cctgcctgtt ctcctccaca aatttctcga acgaagcctc
     7021 gtccggtgcc tgaatagtga gaatagactg aggagcagca tatacattcc ttgcatactt
     7081 gaatttaggc tgggtataga ggtccttgtt cacatcgaca ataatgatat tgcgaatcag
     7141 ttttaaagtg gcatcataat tggaaggggc agtatacatg attcggaatg aacgttctga
     7201 ctggggaagc cccggaacat cagaatcaag cacatcgaaa agcgccctac cggcaggacg
     7261 ttcccacaag ccgggctcca ccactaccag aacttcatac gcacgaccgc tggaggtcgg
     7321 agtaaacaca ccctttttac caccaccgca agcggaaaaa agtgtcagta cgagaaccat
     7381 acttaaataa aacaagtgct ttctcatatc tctatcattt tagtttttca caaagctacg
     7441 aagaatgcgt aatatcctcc ctacctaagt taataattta tattaattct tctttattct
     7501 cctcctgctt ggcagtggac aacatgccac aagcggcaaa tatatcctct ccacgcgatg
     7561 accgtatagt ggtaaacaga ccgtgcgaag tcagataatc acggaacgca gtcatggttt
     7621 ccatatcagc cccttcaaga ttcactccag gtatggcatg aaaacgaatc aggttaatcc
     7681 ggcagtccag cccgcgtagc aacttcagaa gttcctttgc atacggtaac gagtcattca
     7741 ctcctttgaa aacaatatat tcaaaagata gtctgcgctg tttgctaaaa tcatagtttc
     7801 ttaacaattc aacaatctcc gtgatggaga aggccttctc tgccggcatc agctcgcgac
     7861 gttgcaaagg tatcggcgaa tgaaggctga tagccagatg gcagtccgac tcctcaataa
     7921 aacgctgcaa gcccttcttc aatcccacag aagaaagtgt aacacgcttg ggactccacg
     7981 catacccata tgaggcggtc attatttcca gcgctttcaa tacctcgtcc agattatcaa
     8041 gtggttcacc catgcccatc attaccacat tggtaagctt gtccctttcg ggcaacgaat
     8101 tgatttgatt aataatctgg ttggatgtca gattggcagt aaaaccttgt ttgccggtca
     8161 tacagaactt gcaattcatc ttacagccca cctgcgagga gacacaaagc gtagccctgt
     8221 cttcgtcggg tatatagaca gcttccacga aatgcccctc tcctgcccga tacaagtatt
     8281 tcaccgtacc gtctacagag cgcatggcat ctaccggtgc ttcggcacct acctcataga
     8341 tttctttcag caattcccga tgctttaacg aaagattgct catttcgtct atagaagtca
     8401 ccttcttgcc atacagccag gaagctatct gcttggcaga gaaaccgggc attcccagat
     8461 tcttcaccac attctgcaat tcagagagcg tcaagcccaa tagaggtcgt ttctgcatat
     8521 cgtttttcat taaaaacaaa actctttcaa gaatgcaaag g
//
