LOCUS       c00126_gnlPro..         8369 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PECMBOJN_126.
ACCESSION   c00126_gnlPro..
VERSION     c00126_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 02:39:11
            Original ID  :: gnl|Prokka|PECMBOJN_126
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8369
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8369
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[851:5090]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      852..5090
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8369
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8369
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(103..855)
                     /locus_tag="ctg126_1"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYIAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(852..1412)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg126_2"
                     /sec_met_domain="ALS_ss_C (E-value: 4.2e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(1445..3196)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg126_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(3288..5090)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg126_4"
                     /sec_met_domain="ILVD_EDD (E-value: 1.8e-219, bitscore:
                     718.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARLMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             5580..6152
                     /locus_tag="ctg126_5"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(6252..7532)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg126_6"
                     /sec_met_domain="SDH_alpha (E-value: 1.3e-62, bitscore:
                     200.6, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTERQQIIDLVKSEVVPAIGCTEPIAVALCVAKAAEVLGRHPE
                     KITVLLSANILKNAMGVGIPGTGMIGLPIAVALGALIGKSEYQLEVLKDCNPDAVEEGR
                     RFIDEKRIHIALKDGIKEKLYVEVCCEVGDEKSTAIIAGGHTSFVYMARNGEVLLNKQA
                     VASTEKEEGALDLSLRKVYDFALTAPLDEIRFILETARLNKAAAERSFEGDYGHGLGKI
                     LRGTYEHKVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISATLPVLIYAE
                     ENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLMGGTYEQVA
                     YAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEGIIDEDVDQ
                     SIRNLTKIGSKGMNETDKLVLEIMTSK"
     CDS             complement(7679..8368)
                     /locus_tag="ctg126_7"
                     /transl_table=11
                     /translation="CSDDDDDKIKDPVIGTWKVPAVELDENNSVIGGSVFMTWEAPEDT
                     YLSFLPVSAIPSLAIQGSVILPQVLQDVTLSADGNIVATYSSAGIDLLGEKPITPVWET
                     SPADYATFKLQGNGKMLLFLNLEKIIADANTKADITTVISQLLELVKNGIPVNYALSNN
                     NEEVKIFIDKELMTTIAAMGPAIAELIPDDPDALGSFGPMIKAILGDLPTAMSKTTKFE
                     LGLNLKK"
ORIGIN
        1 cttcgcgggt cattacgttc tcagtaacac cgccaaaatt caattgtgcc attttttgtt
       61 ttaattttta tttgtggctt acgccaacgt tgataaattt atttatttct ctgtaaatat
      121 cactttagag cgacagacca cttcgctgcc attctttttc acctccacat cgtaaacgcc
      181 ctcaccggca tcatccatga acaaagtcaa ctcatcccca taatagcttt cggctatata
      241 tgccatttca aaacgacgga tgcgcttctc cttatacatc tctatcggga acaaatcaag
      301 gatatgctcg atgtaacgga tgctgttcac atgcccgtta atgtcaatat cactgtattt
      361 ggctaccaaa gcagcaaccg gttcctttga ggccaccttt atccgcgaag gtttttctat
      421 cgggcaaggc tcatcgcaaa cataatctac aatgctgcca ctatgaagag ccagcaaatc
      481 tgccggctta cgggtattca tgctaatcat cgcccaaacg gaacgtgcat acccaatctt
      541 cttaccctcc ttatcgatga tagcgaaatt acggtctgta aaaaggcgat agacattctc
      601 cacccaagtc tgaatggaga aatcttcgta ctgataaggc atttcatcca gttcgacagc
      661 cagacgggac aatacccaag tataattgtc ctcgtttaga gtcgcgatgc caaaaccgcg
      721 gtcgctggca tggaaacccg cacaattcaa caaatggttg cccaatactc ccattgtcag
      781 ccgtccggta aagtcgacat gaaacggttc ggcaacaaac ttgtaggtac ctatcttatt
      841 gttctcgctc atcatgattc ctggtgttta ctttgacgat attttgcttc acggtccgcc
      901 agatattcat tgacacgctc aaagcagctg gtcgtaatgg ctacgcgacc cgaacggacg
      961 aactgaagta cgcaatccaa ctggcgcaac tcctcataaa gattggttat ttcctcactc
     1021 atgccattct tctcaacaat ggcaaataca gcattcacct ccacaatacg ggcattgtac
     1081 ttacggatta ctttggacac ctccggtttt tcttccagcg taggggtcgt tattttataa
     1141 agggcaatct cgtgctgata gatttcatca tccgtgaaat aatgggcttg cagcacatct
     1201 attttcttgg taatctgctt ggtcaccttt tcaatggtat ccttgtccgt ccaagcggta
     1261 atggtatatt tatgtacccc cttgatggag gaggccgata cattcaaact ctcgatgttt
     1321 atctgccggc gggtaaacac agccgtcacc tgattcagca aaccggcaaa gttttccgaa
     1381 tgaacaatga ttgtatatag ttttttatcc atagatagag taagttcttt aatttcgcat
     1441 gacttcagca ttccaacaac atctgattga ccgaaccgcc cggaggtgtc atcggcatta
     1501 catttccttc ttcctccaca caagcttcga gcaggaacgg tccgtcagtc gctatcatct
     1561 cgtcaatcgc ttttgccagc tcctcgcggg tcattaccct gcgtgcagga atatcatatg
     1621 ccgaagcaat cttcatataa tccggattca tcatcggagt aaacgaataa cgacgattga
     1681 agaacatcgc ctgccattga cgaacattgc ccaggaagtt attgttcaac agaatcatct
     1741 tcaccggagc cttttgttcc atgatggtac ccagttcctg caggttcatc tgcaagccgc
     1801 cgtctcccat gaatacgcat accgtgcggt ccggacgtcc aaaagtggca ccgatagctg
     1861 ccggaaggcc gaagcccata gtacccaggc caccggaagt aacaatgcta cgttccttgc
     1921 tgtatttgaa ataacgggcg gacatcatct gattctggcc gacatcagtc accaatatcg
     1981 cctcgttatg ggtagcctca ctcacagcac gcaccacctc acccatgctt agcgcttttc
     2041 ctgccggatg taattccgga cggattacct tttcctcttc cacttcctcg tattgccgga
     2101 aactgtcaat ccattcctga tggttggcgg gttccagcaa ttgggtaacg gcagccagtg
     2161 tctctttgca atctcccagg acagcaacat cggtctttac attcttatct atttcggcag
     2221 ggtcaatatc aaagtggata atcttcgcct gcttggcata tgtttccaat ttacccgtca
     2281 cacggtcatc aaagcgcatg cctacggcga taaggacatc acatttattg gtattgatat
     2341 tgggccccag gttaccgtgc ataccaagca ttcctttgtt caacggatgg ttcgtaggta
     2401 atgcggaaag tcccaataaa gtgcatccgg caggcattcc ggctttctca atgaaagcac
     2461 gaagctcttg ctgggcttct cccagctcca cgccttgtcc taccagcacc aaaggccgtt
     2521 ccgcaccatt tattaattca gcagccttcc gtatggcctc cggctccatt tcgggaacgg
     2581 gaagatagct acggacatag tccaccttag taggcgcata ttctgttttc tccacttggg
     2641 cgtttttagc aaaatccagc acgaccggtc ccggacgtcc gctctttgcc acatagaaag
     2701 cacgtgccac tgcccaggcc acatcttctg cacgacgaat ctggtaactc catttcgtga
     2761 taggctgagt aatgcctacc aagtccactt cctgaaatgc atccgtaccc aagaagttcg
     2821 tccctacctg gccggcaatg acaacgatag gcgtactgtc aatcatggca tctgcaatgc
     2881 ccgtgatagt attggtagca cccggtccac tggtaaccag acaaacgcca acctcgcctg
     2941 atacacgtgc aaagccttgt accgcatggg ttgctccttg ttcatggcga accaagatgt
     3001 ggttcaattc cttccggtgg tcgtataagg catcgaatac cggcatgatg ctccctcccg
     3061 gataaccgaa aatagtcttt actccctgat gctccagaga gcgcatcaat gcttctgcgc
     3121 ctgttattag agcctcaccc cgaccctctc cttgggagag ggaggaaaag ttactctttt
     3181 tattattatc agccatactt tatctattca ttatatttaa aagctcaata gtagcttgaa
     3241 aaatttgttt cattctctcc tcccctcgct ttcggaaagg ggggctttta atcaatcagc
     3301 ctcacagccc ctttgtcagc ggaactcacc atactggcat atgctttcaa tgctttggag
     3361 acttcacggt tgcgggttac cggagtcata aggcgtgctg caagctcttc atccgtcaac
     3421 ttcacattga tagaacggtt cggtatatca atttcgataa tgtccccatc cttaatcttg
     3481 ccgatattac caccggcagc cgcttcggga gaaacatgtc cgatacttag tccggaagta
     3541 ccaccactga aacgcccgtc ggtaatcaat gcacactcct tacccagatg gcgggatttg
     3601 atataagaag taggataaag catctcttgc atacccggtc cacctttcgg cccttcgtga
     3661 gtgatgacga cgacgtctcc actgaccacc tttccaccca gaataccgtc acaagccgca
     3721 tcttgtgagt cgaagacttt cgctggcccc gtaaatttcc agatactctc gtctacaccg
     3781 gcagtcttga caacgcaacc gtcctgagct atatttccct tcaaaaccgc cagaccgcca
     3841 tccttgctgt atgcatgttc caaatcacgg atacaaccgg tcgcacggtc cgtatcgagt
     3901 tccttataag acgcattttg tgagccgagt accagattga actttccggc tgccgcactg
     3961 gagtatttct tgattgcctc tttacataca ttagagctgg taatactata ccggtcgatt
     4021 gcctctgcca acgtcattcc atccacacgg cggacattcg tatcgaccaa tccgcccttg
     4081 gcaagctcat ccatgatggc aatgatgcca ccggcacggt taacgtcttg tacatgatac
     4141 ttttgggtat tgggagccac cttgcataag cagggggtct tgcgggagag catgtcaata
     4201 tcgtccatct taaaatccgc tccggcttcg tgagccacag ccaacaaatg aagtaccgta
     4261 ttagtggaac cgcccatcgc aatatccagc gtcatggcat tcaaaaatgc ctcgcgggta
     4321 gcaatactgc gcgggagtac actctcatcc ccttcttcat aatatctaaa ggcattctct
     4381 acaatcaacc tggctgcatc ctcaaatagt ttcttgcgat tttcgtgagt ggctacaatc
     4441 gtgccgttac cgggcagtgc caatccaatc gcttcattca agcaattcat ggaattagcg
     4501 gtaaacatgc ctgagcagca tccgcaagtg gggcaggcat gttgctcaat ctgtgccacc
     4561 tctttatcgc ccacactttc atcagcagat ttaatcatgg catcaatcaa atccaaatgc
     4621 tgtccgttcc attccccggc ttccatcgga ccgcctgaaa caaacacagt cggtatattc
     4681 agcctcatag ccgccatcag catccccgga gtaatcttgt cacagttact gatgcaaacc
     4741 atagcatctg ccttatgggc atttaccata tactccacac tatcggcaat gatatctctt
     4801 gaaggcaggg aataaagcat accgtcgtgt cccatagcga taccgtcgtc aatggcaatc
     4861 gtattgaact ccgcagcaaa acaccccagt ttttcaatct cttcctttac aaactggcct
     4921 atttcgtgca ggtgtacatg cccggggacg aattgtgtaa atgaattgac tatagcgata
     4981 atgggcttac ccatctgttc cttcttcata ccattcgccg tccacaatgc acgggctccc
     5041 gccatgcggc gaccttgtgt gctgaacgag ctgcgtaact gatgcttcat tttcaaatct
     5101 ccttttaatg aaaaagcctc tcccactata gtgagaaagg cttaataaat tatcttctaa
     5161 cgtacgaata catacataac ctttctcacg ctcttgatgc caccaccacg acgcgaataa
     5221 tatgcaggac tgccaggtta atagatgtat gtaaattcat aacttaattc ttcttttttg
     5281 tttcaaacgt gctgcaaagg taagggcttt tttataatct ccaaacaaat tgaagaaaaa
     5341 aataagataa atatgaataa tcgtaagaaa atatcgccct aaaatcctat tttatcactt
     5401 aacagttcta aatagaacca ttcagacagc caatgtaaat gtattgccaa tcattgaaac
     5461 catttaataa tctgaaaatt accaaaggct ctctacatcc cgaaacaaat aattcgtatc
     5521 tttgtctctt caaatactca aaaaaaagta tttactaatt aaataaagat agaaaattaa
     5581 tggaaacagt agaaaacaag tacatcaccg tagcatataa gctgtactca atcgaaaacg
     5641 gagaaaaaga tttcgaagaa gaagcacccg tagagcatcc ttttcagttt atctcaggtc
     5701 tgggaatgac actcgaaccc tttgaagccc agataaaaga cttgcagata ggcgataaat
     5761 tcgactttac cattccggca tcagaagctt atggtgaata tgacgacgac catgttattg
     5821 acctccccaa agaaatcttc atgatagaag gagaattcga cagcgatcgt gtagtagaag
     5881 gtgccgttat ccccttgatg acttctgaag gtcaacgcat caacggaagt gtggtagaag
     5941 tgaaggaaga tatcgtcgta atggatatga accatccgct cgcaggttgt gacttgaact
     6001 tcactggaga agtagtggaa agccgcctgg ctacaaacga agaacttgcc gaagtcgccc
     6061 gtatgatggg tggcggttgc ggcagctgcg gttgtggtga ctgtggcgac ggatgcggcg
     6121 accatgaatg tggaggcgga tgctgccact agaagaatta aaaatgaaga attaaaaatg
     6181 aaagaatcaa actacgcaat ataagtatgc tgcatgataa ttctttcatt tttaattctt
     6241 cattttttta attatttact tgtcattatc tccaatacca atttatccgt ttcattcatt
     6301 cctttagaac cgatttttgt cagattacgg atactctgat ccacatcctc atcaataata
     6361 ccttctacgg aagttacaca acggttttcc atggccatga tggctgaaag tactgcggtt
     6421 gaaactccgg tagtcacttt caatgcacaa ctaggtttgg caccatcaca aatcattccg
     6481 gtaagattgg caatcatgtt ctgtacagca tatgccacct gctcataagt accccccatt
     6541 agccaagtta taccgcaact ggaaccagtg gcagcaacca cacaaccgca taaggcggat
     6601 aaccgtccca aactctgctt gatatagatt actgtcaaat ggctcaacat caaggcacga
     6661 atcaattctt cttctgattt cccgttttct tcggcataaa tcaaaaccgg caacgtagcg
     6721 gatatacctt gattaccgct tcctgaatta ctcatgaccg gaatcatggc tcctgccata
     6781 cgggcatcgc aagcaccgga agtataagaa agaatatggg aaaaaacact gtcccccata
     6841 accttgtgct cataagtacc gcgaaggatt tttcccagac catgtccgta atcaccctca
     6901 aaagaacgtt ctgcagccgc cttattcaga cgggccgttt cgaggataaa acgaatttcg
     6961 tccaacggag ccgtcaaagc aaaatcatag actttccgca agcttaaatc cagcgcacct
     7021 tcctcctttt ctgtgcttgc aacagcctgc ttgttcaaca gcacttcccc attgcgtgcc
     7081 atgtatacaa aggaagtgtg tccacctgca atgatagcag tggacttttc atccccgacc
     7141 tcacaacaaa cttcaacata aagcttctct ttaatgccat ctttcagtgc tatatggatg
     7201 cgcttttcat ctataaaacg tcttccttct tccacggcat cgggattaca atccttcaat
     7261 acctccagtt gatattccga tttaccgatt aaggcaccaa gcgctactgc aataggcagc
     7321 ccaatcattc ctgtaccggg aattcctacg cccatcgcgt tcttcaagat attggcactt
     7381 aaaagaaccg ttatcttttc cggatgtctg cccaatactt ccgcagcttt tgccacacac
     7441 aatgccacag ctataggttc tgtgcaacct atagcaggaa cgacctcgga tttaaccaaa
     7501 tcaataatct gttgtctttc cgtttttgtc atatttattc aatttagatg cagacaaagg
     7561 taatgtattt tattctataa tagaaggaat agaaggaata aaataaatcc cactattaag
     7621 acattgctta atagtgggat tccctatctt aagttgttat cttcctgtct aaattagatt
     7681 actttttcaa attcaaaccc aattcaaact ttgtagtttt tgacattgca gtcggaaggt
     7741 ctcccaatat agcttttatc ataggaccaa aactacctaa tgcatccgga tcatcaggaa
     7801 tcaattctgc aattgccggt cccatagcag caatagtagt cataagttct ttatcaataa
     7861 agattttcac ttcttcatta ttattagaca acgcataatt cacagggatt ccattcttca
     7921 caagttccaa caattgagat ataacagtag ttatatcagc tttagtatta gcatcggcta
     7981 ttattttttc cagattcagg aaaagcaaca ttttaccatt cccctgcaat ttaaaggttg
     8041 cataatctgc cggtgaagtc tcccataccg gagttattgg cttctcacct aaaagatcta
     8101 tccctgcaga agaataagtg gccactatat taccgtcagc actcaaagta acatcctgca
     8161 atacctgcgg caatatcaca gacccctgta tagctaacga cggaatagca cttaccggca
     8221 aaaatgatag atatgtgtcc tcaggtgcct cccatgtcat aaaaacacta cctccgatca
     8281 ccgaattatt ttcatccaat tcaacagccg gaactttcca agtaccaata accgggtctt
     8341 taatcttatc atcgtcgtca tcactacaa
//
