LOCUS       c00018_gnlPro..        13701 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPEBOOIF_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:45:28
            Original ID  :: gnl|Prokka|GPEBOOIF_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13701
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..198
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="GACLGFVRHFQVRSPGLLEPFRCNNFLRCATMRKQLSGILFLVQG
                     NLVMKKLPTADAAGSFYRAS"
     protocluster    1..13701
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[211:3701]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      212..3701
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(212..979)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1020..2978)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3000..3701)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3902..4174
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4177..4992
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRTMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5026..5259)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGE"
     CDS             complement(5689..6396)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRCRRA"
     CDS             complement(6427..6516)
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             6691..7431
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(7726..7974)
                     /locus_tag="ctg18_11"
                     /transl_table=11
                     /translation="MRVSPSFIPEQDAVAIHGSRIVGNIVDATSVIRADDGKEYEVLGM
                     GPIAVLPEYQRRGIGRRIIGMRRPSRSVSCKGDPYPA"
     CDS             complement(8108..9313)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMIAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPTKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9337..10083)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_13"
                     /sec_met_domain="adh_short_C2 (E-value: 2.1e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10107..10727)
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAASKDILENSDEFSDLVEPDENGAPPMH
                     SGKMKRPDSSPPPRFSPLFFIPGTPFPRMGSCAAKSISSLPEP"
     CDS             complement(10790..12400)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12523..13230
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ggggcctgct taggtttcgt ccggcatttc caagtacggt ctcctggatt actggaaccc
       61 ttccggtgta acaatttttt acgctgcgcg acgatgagga agcaactgtc tggtatttta
      121 ttcctggttc aaggaaacct ggtaatgaaa aaactcccga cagccgatgc cgccgggagt
      181 ttttacagag cgtcttaaga aggaatcttc tttagaaaca gaggccttcc ttggcgttgg
      241 cccgcatgaa gtcgcggttg aggcgggcga tgttgtccac gctgatgcct ttcgggcagg
      301 cggcttcaca ttcatactgg ttcgtgcagt tgccaaagcc ttccgcttcc atctgcttca
      361 tcatggccag gacgcgcttg gaacgttccg gctggccctg cggcagcaga ttgagatggg
      421 cgatcttggc ggaggtgaac agcatggcgg aggcgttttt acaggaggcc acgcaggcgc
      481 cgcagccgat gcaggcggcc gcgtcaaagg cggcgtccgc tttcactttt tccacggcga
      541 tgttgttggc gttcggcgcg gaaccggtac gcacgtcaat atagcctcca gcggcgatga
      601 tgcggtccag ggcggagcgg tccaccatca ggtcccgcag gattgggaaa gccttcgcgc
      661 ggaagggttc aatccagacg gtatcgccat ccttgaactt gcgcatgtga agctggcaag
      721 tggtcacctg gcgttccggc ccgtggggaa tgccgttgat ggtcagggag cacatgccgc
      781 agatgccttc ccggcagtcg tggtcaaaat ggatgggttc cttgccttcc ttgaccaggc
      841 cttcattgac gatgtccagc atttccagga aggaggcgtc caccggaatg tccttggcgg
      901 cataggtctc aatgcggccc ttggcttccc ggttttcctg gcgccagacc ttgagagtga
      961 gattgagtgt tttagccatg ttataatctt tcttttgagt gttaatgtat tggctatctt
     1021 tacttgtagc tgcggatggc aaggtgcacg ttctcgaagg tcagcggttc cttgtggaga
     1081 acaggcaggc tgtccacgcc agtgtattcc caggcggcta cataggcgta ttcatcgtcg
     1141 ttgcgcttag cttcgccgtc cggcagctgg tattccacgc ggaagtgggc gccgcaggat
     1201 tcctggcggt tcagggcgtc atagcagagc agctgggcga attccaggaa gtcggccacg
     1261 cggcaggctt tttccagttc cgcgttgatg ccgtccgccg tgccggttac gcgcacgttt
     1321 tcccagaatt ccttgcggag ctggggaatg cgttcaatgg cgtgggtcag gctttcttcc
     1381 gtgcgggcca tgccgcagtc ttcccacata atgaggccca gttcccggtg gaaggagtcc
     1441 accgtcttgg tgcccttcac attcaggagc ttgttgatgc gttccttcac ttcgtcttcc
     1501 gcagccttga attccggggc ggcggtggtg acggcgccgg gtttggtggt cgtcaggtaa
     1561 gcgggcagcg tggcgggaat gacgaagtag ccgtcagaca ggccctgcat cagggcggag
     1621 gctcccaggc ggttggcgcc gtggtcggag aagttggctt caccgaggac gtgcagcccc
     1681 ttcacattgg acatgaggtt gtagtccacc cacaggccac ccatggtgta gtgggaggcg
     1741 gggtagatca tcatgggcgt ttcatggggg tcgtcgtccg tgatttcttc gtacatgtca
     1801 aacagattgc cgtattggcc gtcaatccat tcgcggccca tgcgcttgat ttcatccgca
     1861 aaatctagga agacgccctt gccggtgacg gccacgccgc ggccgtcgtc gcaggcttcc
     1921 ttggcggcgc gggaggaaat gtcgcgcgga gccaggttgc cgaaggaggg atacttgcgt
     1981 tccaggtagt agtcccgttc ttcttcggga acatcggaag gcttgatttc ctttttacgg
     2041 attttttctg cggtttcacg ggacttgggc acccagatgc ggccactgtt gcggagggat
     2101 tccgacatca gcgtcagttt ggactgatag tcgcccttga ccggaatgca ggtggggtgg
     2161 atttgcgtga agcaggggtt ggcgaagaag gcaccgcgct tgtaggcctt gtaggcggca
     2221 gtgacgttgc aacccatcgc gttggtggac aggaagaaca cgttgccgta gccgcccgtg
     2281 cagagcagga cggtatcccc tgcgtaggat ttgatttcgc cggtaaccag attgcgggtg
     2341 acgatgccct tggcttcgcc gtccaccagc accagatcca tcatttcatg gcgggagaac
     2401 atttcaatgt gtcccttggc cacttccttt tccagggcct ggtaggcacc cagcagtagc
     2461 tgctggcccg tctgtccgcg tgcgtagaag gttcgcttga gctgggcgcc gccgaaggag
     2521 cggttgtcca gcaggccgcc gtattcacgg ccgaagggaa cgccctgggc cacacactgg
     2581 tcaatgatgt tggaggagac ttccgccaga cggtagacat tggcttcacg ggcgcggaag
     2641 tcgccgcctt taacggtgtc gtaaaacagg cggtaaacgg agtcgccgtc gttctggtag
     2701 ttcttggctg cgttaatgcc gccctgggcc gcaatggagt gggcgcggcg ggggctgtcc
     2761 tggtagcaga agcatttgac gttgtagcca agttcggcaa gcgtggcggc agcggaggcg
     2821 ccagccaggc cggaacctac cacaagcacc gtgtacttgc gcttgttgtt cggattgatc
     2881 agtttggact caagtttgta cttggaccat ttgtcctgaa tagggccgga gggaattttg
     2941 gcatccggca tccagtcgct tacgggaaaa ttaatcatga ctttgagagg agttgatggt
     3001 tatttgatga tacccagaag aaccgagacc ggcacggaga tgaagcccag gcagataatc
     3061 gcgccgtagg cgatggcgat aaagttgtag aagggccgga ttttgcggga atcgacgccc
     3121 acagtctgga agatggactg taccccgtgg cgcagatggc tgaacagcat cagaacggcc
     3181 aggatgtaga aggcggagca ccatacgttg gagaatccgg tcacgatcat cttgtacacg
     3241 tcaaaggttt ccaccgtacc gtcggaaatg aaggtggtga actgggcggg gtcgtatccc
     3301 acgcgcaggg tgtactggta caggtggtag atcaggaaca ccaggacggt caggccggta
     3361 tagatcatgt agcgggagga gagcgtcgcc ttgatggtgt tcttgaacac gtagggttcg
     3421 cgggccgcat ggttttccag cttcagctgg atggtcagcc agacgtggat gatgaagatc
     3481 accgcaagcc ccgcgcggat tccccagagg gctgcttccg gcatggagtg caggccgtgg
     3541 gcgtaggtgt tgatccattc agggcctccg aagatgagaa ggttgcctgc caggtgtccc
     3601 gcaaggaaca agaccaaaca taaccccgtc agagccacaa tgattttgcg gccgatggag
     3661 gatgtcacga atgtacatat ggtttttact agtgcattca taggcgctct aatgaaataa
     3721 atgcgtcttc acaggatgcc tggttcaagc ccggatggca agcctcttct tgaatttccg
     3781 gcgcttttcg gatttttgaa aagccgggga aagatgttgc tgtttatcag tttggaatgg
     3841 ttatcatttt gttgcctgtt ccggcttgac gaggctttcc gcataggcgt atcgtctgtg
     3901 catgaaaaga agtaaaaagg aagtgctgga cgcggatttc gcagcggcgc gcgccggcgt
     3961 tctggatgtg gccgcatttc tggaccgggt ggaccgcggg gaaggggagg cggatttccg
     4021 ctaccatgcc ctgatggatg ttcttcccct cttatccgca tccggccccg gacgcgtccg
     4081 ggccatcctg gaagcccttt cctacaggga tgacaccgtg ccggaaaccg ccgcagccaa
     4141 agcggcctgc ggagccccga acctcagcaa ataagaatga tggctttcat agaacctcat
     4201 atacatatgg tgtgccgcac cacggacgaa taccggacca tggcgcaggc cggctgcctg
     4261 gcggtagggg aaccggcgtt ctgggccggt tacgaccgtt cgtccgcgga cggtttccgg
     4321 gattatttcg tacagcttac ggaatgcgaa cccgccaggg cggccaagtt cggcatggac
     4381 cattacacat ggctgtgcat caatcccaag gaggcgcagg acgtggcttt cgcgcgggat
     4441 gtgatgaagc tgattccgga gttcatcgac cggcccaatg tcctcggcat cggggaaata
     4501 ggactgaacc ggaatacttc ccatgaaatg actatttttg aagagcatct ggatctggcg
     4561 gtgcgcctca accagcttgt gctgattcac actccccatc tggaagacaa gcttaagggg
     4621 accgtaatga ttctttccgc cctgaaaaac cgtccggatc tggacccttg ccgcgtgctg
     4681 gtggatcact gtgaggaaca taccttcccg ctggtgaagg aggccggtta ctgggccggg
     4741 ctgacccttt atcccaccag caagctgaat cccaagcggg cggcggatat tctggaattg
     4801 tacggaatgg accgtgtctg ggccaattcc gcggcggact ggggggattc cgatcccctg
     4861 gcgctgacgg ccctggcctg cgagctgcgc aggcgcggtt tttcccggca ggaaacggaa
     4921 cgtcttctcc tggaaaatcc ggagacattc atgggacagt ccccgaagtt ccggaaagtg
     4981 tcgtcccgtt aattccgccc gcggcgcggc ggagggtacg gccctctact ccccgtccgg
     5041 gaaaaagacg gtgaggacgg cgcccaggat gaccgccgcg tcatccagaa ggcccagcct
     5101 gccgattccg tcaaacagga attcgtcggg agtcaggatg taggcgccgg cggcggccag
     5161 aaggcatata ttccgtttgt tgaaaaaacg cggttctcct tttctgcttt tgaaataccg
     5221 gaacaggcgc agtagcagct gctgtttttg aaggttcatg gatgggaacg ggggataaag
     5281 gttcaagttc agccattttc ccactccttt tccctgtttc agggaaggag tctgttgccg
     5341 acggacggaa accgcagcga tccggaccgt gcggggaaat ggattgctga aaggatgggc
     5401 tgttccggat gctgagggaa gccgggcttt gcatgctccg gttccggctg tcccggcatg
     5461 ggaaaaaggg gcgtgtacgg aagtggggcg gggccggaag ctcttgaaat gaccctcccg
     5521 ggggagcctg aatgccattt ccccgtcaag tgctggccgt gagggtagcc agcaaataga
     5581 agcttcttcc ccctgttttt tccggcagat gtttgaacgg ataaggaaaa ggccggctca
     5641 cgattttgtg agccggcctt tgaatatagg gaggcggacg gtacaggctt atgccctgcg
     5701 gcagcgcatc atcagcgcgg ccagtcccag caggcccagg gaagccgtgg cgggttctgg
     5761 aatgctggcg atttcactca tcagctgacc aacttgttcc tgggaaagga gggagtcgtg
     5821 gatgtagagc tgttcgatgg attcagccag tcctgcgtcc atgagaatct gattaatttg
     5881 ctggttgccg aatttcaggc cgctgttgga atagtacgta gcgctgtctc caaaatagat
     5941 gcgggtgcca agatctccgg tgactacgga aatggtcagg gaaccttccg tgcccagcgg
     6001 ggtgtcaacg acgggcccgc tgtatgaggt gttgttccat aatccctgga gtttccggtc
     6061 cgtgttcagg cccacgcccc agcttacact gctgtttttg gcgttaaaca gagcggtata
     6121 ggtctccgga gtgttgattt tggacaggtc aagaaccatc gtcacagaca taacgtcgcg
     6181 gttgttggca ccgtatccgt tgaaggttat cccggacaac gtcagattgc tgtcgtcaga
     6241 cgtgatggaa acggaatctt tccgggtgcc gaaatccgcc gtttgggagg caaagtccga
     6301 atatcccacg atggagctat ccaacagagc ggtagccgcg gtagcgctta ggctcatgcc
     6361 ggccgaaaga atcagggtgg ataataattt attcatggtc agtatcttaa taaaatgatt
     6421 caaggttcaa tgtatgtact tgtgcttgaa taacgaattt ggaatccgca agcaattaaa
     6481 aatattaaga gttagtatat tgtatttata attcattgaa aataatgatt ttttaatatc
     6541 tctggtcctt ttgctaagat gacggggcag tctttgttat tcattggttt catgattgat
     6601 ttggcctctt tttcattact tgacggattc caaatccgat tggggaattc caaattcgct
     6661 acaagttgcc atccaaaagg aataataaat atgaagaaaa cactgacatt tttaatcgcg
     6721 atgggaagct ttgctgtttc ctcggaggca gcgaccgttt ttaattatta cactcccggt
     6781 acggataatt acaatagtac catccatggg ttttatcttg gcctggggtc ttcttccctg
     6841 gctccttccg attcctcttc tccctcctcc ctgtccggag agatcagact ggacagtttt
     6901 acgctgcgcg gagccgccaa caatttgggc gctaatgtca cttacggctt cctggtgctg
     6961 aatggctccg acaattcggt catcggctgg agcaccaata cgggaactac tgcagcaggg
     7021 attaatctga cgttcagttt ttcttccctg gatggttctc ccctgcttct tgacgcggca
     7081 ttgacatacc gtttcctggc cgtgagccag tccgtgatgg acttgatgca ggatacgtct
     7141 aaaacgtatt tatatgctgc ggggggaaca gccgccccta ctgctaacac ggaaggagat
     7201 accgtaacga tcagcggcgg attgactgct cccggcatcc gcggccatta tgacgccgag
     7261 ggagcgcctg gtgattctgt cgttattacg ggagccaacg gaaccaatac tttcagctta
     7321 ttatccccga ttttcacgga aatccgaggg gaaatggtgc cggaaccagc cacggtttcc
     7381 ctgggcctgc tgggactggc cgcgctgatg atgcgccgcc gcagggcttg agcttcctga
     7441 tggcgaaaaa tcggcggatg agagctgttc ttgcggaaca gctcttgttt tttatatcca
     7501 gagaggaaga attgcttatc cgtatgcggg attcatgccc tccggaaggt acggaatttc
     7561 cgggggcagg gggccgtatc cggttttttc cgcatggcgg caatttgctg gaaacgtttt
     7621 tgagacgcag taccggaaag ctttttcttt accggaaaat gccgtcaaat tcggcagcgc
     7681 gcttttcgtc catatggtac acagtagctt tcacatagcg gcctttcagg ccggataggg
     7741 atcccctttg cagctcacag acctggaggg ccgccgcata cctattatcc gccgtcctat
     7801 tccccggcgc tggtattccg gaagaacggc aatgggcccc atgcccagca cttcatattc
     7861 ttttccatcg tctgccctga tgacggacgt tgcatcaacg atgttcccga cgatgcggct
     7921 gccgtggatg gcgactgcat cctgctccgg gatgaaggaa ggactgacgc gcatgatatg
     7981 gagcaggtaa tgttcattgc agccggggac gaaatagttt cagaacgctt ctctcgtgac
     8041 atgttccgtt tcggcatggt ctgaggattg ttccgttctt aatgcaatgg tcatgaaaga
     8101 ttgttcttta cggctccccc ttggagaaat tccagaggcg gtgcatcgtc ataatgtccg
     8161 gaatgttcat ggggcgcacc acgcggaacc cgatcatgcc tccgtccgtc aggtaccaga
     8221 tgcttttagg gttttgagga tcctgacggt tccaggcggg ggtgctggcg cggcgcgcag
     8281 cgcttctcag gctgtccggg tcgtcttccc acgaaccgcc gcgaacgatg tgaggggcgc
     8341 cggggatgat gactaggggg tctttcgtgg gcaagccgct ccgtttgccg taggcatccg
     8401 gaacgtaaga gtccaaaacc cattccgcca catttccgtg catgtcccgg agtccccact
     8461 tatttggttt tttagagcct gttttctggt agcggtcatt ggaattgttc cagtaccagg
     8521 cgtactggtc cagagaggct tccccgtttc cgtaagaata ggcgccggcg gaaccggccc
     8581 ggcaggcgta ttcccattcc gcctccgtgg gcaggcggta gtaatgcccg gtctgggcgc
     8641 tcagccattc gcagaatttg ctggcggcgt ggtgggacat ggagatggcg ggcaggccgt
     8701 gttcatagcc gtggcccatg cccaggttca tggcggcgta gggggcggta ggctgcgtga
     8761 cggagtccca cagttcgtca tccggctgtt cctccagaag ctggccgtcc ttggcgcgcg
     8821 gacgcccgtt ttccatgaag gccgtataaa gttcccaggg gatttccgtt tccgagatcc
     8881 agaagggaga gatgctcact ttatgctgcg gaccttcgtc cggtttccgg tgcggctctt
     8941 ccgcgggact ccccatgagg aacgttcctc ccggtatggc gatcatgcgc agggaagctc
     9001 ccgccgcggg aaccgtttcc gtgtaggatt caaaacgtgc cggatttccg gaagcttcaa
     9061 tgagctgatg gatttggcgc gtcgtgccga ccagctcccg ggacggcagg tcatccggaa
     9121 tgggaagggc aggaccggca gcgcggtcca gttcccgttt ttgcagcgcg gatcggcttt
     9181 ctccccactg gcgtgcgctg gtaatgcgcg cggcatcttc cgtggccggg cggggggaat
     9241 tattttcttc ccggcacccg gccagcaggg cgcttcctcc cagaaagcag gaaacaagga
     9301 aaatgccgcg catggaatgg tgaaaaccgg aatgccctac atcgtcatgc ctccgtcgca
     9361 ggcaatgacc tgcccggtga tgtaacgggc atcgtcagag gcaaggaagg ccgtcagggc
     9421 ggcgatatct tccacggaac cttgttcttt caaaggtatt ttcttaacga tttcttcctt
     9481 gagattgtcg ggaatggcat tggacatttc cgtggagatg aagccgggag caatggcgtt
     9541 gcacgtgact ttgcgcggag cgaattcctg agccagtgat ttggtgaaac cgatgaggcc
     9601 cgccttggaa gcggcgtaat tagcctggcc gatgttgccg acgagaccga tgacggagct
     9661 catgttgatg atgcgcccgg ccggggattt catgagaacg cgctggaggg ccttgactgt
     9721 attgaacgcg cttttcaggt tggtgtccag aacggcatcc cagtcttcct ccttcatgcg
     9781 gagcatcagg gagtcccgcg tgatgccggc gttgttcacc aggatgtcaa tctgcgggaa
     9841 gtctttcaaa atggcggcca tggtttcctg aacggccgcg taatccgcta cgtcgcaggg
     9901 gtaggccttg caggaatccg gaaattcctt gttgatttct tctgcggccc ccccgcagct
     9961 ggatggactg cggctgatca ggatgaccct ggctccttcc gaagcgaagc ggcgcgcgac
    10021 ggcattgccg attccgcggc ccgcgccggt aacgatggct gttttacctg ctaacttttg
    10081 catgctgccc acagtaaacc cgtttttcac ggttccggca agcttgaaat ggacttggcc
    10141 gcgcaggaac ccatacgggg aaagggcgtg ccgggaatga aaaagagggg ggagaaacgg
    10201 ggcggggggc tactgtccgg cctcttcatt ttcccggagt gcatcggggg cgcaccgttt
    10261 tcatccggtt ctaccaggtc gctgaattca tccgaatttt ccaaaatgtc ctttgaggcg
    10321 gcggaaccgt aatagcgggc ctcaaacagg cgtttgcctt cctgcctgca gcggttgtcc
    10381 agcatttcca ttcgtttttc cattttttct atcaaggcgt cttctttctc cttttccgca
    10441 tcgttcaatt tatcctgaag ctggaggaaa tgccggatgt ccttctgaat gtcctgcagc
    10501 gttttgacgg cgttgtccgc gctttccttg tcctgaactc ctgccaacgt ctgctggata
    10561 ttgatggcaa aggaaaaggc ctggttgatc agggattccg cggaaggaat tttttccgcc
    10621 ggagccgctg ctgaggggga agccgttccg gcggccgttt caccaaatgc aagagaggct
    10681 ccggacagaa gcgcagaata taagagagga acaagaaaag ccttcatcct gttcttttaa
    10741 ggcaggagaa atccacggca aggaaaaagg ggaaactgaa aaaagagcct tattccgccg
    10801 tgatgccgcc tttttcatcg tccagaatgc ctgacttttc cagatagtag tcatatccgc
    10861 ctgcgtaggc ggtgatggtc ccccggttca catgcagggt tttttgtgcc agggaacgga
    10921 tgaagtgcac atcgtgggag atgaagacca gtgttccttc ataatgcttc agagcctgca
    10981 ccagggcttc tacggacaaa aggtccaggt gggtggtcgg ctcgtccatc agcaggaggt
    11041 tgggcggatc caccaggaat ttgaccaggc tgagccgcga tttttccccg ccggaaagaa
    11101 cgctgacgcg tttttccaca tccagcctcc ggaacaggaa ggaacccagg atggaacgcg
    11161 cttcttcctc ccggatttca gcgctgcatt tcatgatttc ctccagcacg gtattttccg
    11221 gattcaggtt ttccgttcgc gcctgggaga agtagccgat gcgcgtcgtg gtaccgggag
    11281 tgcgttgtcc ggagtcaatg gggatgatgc ccgccaggat tttgagaaga gtggatttgc
    11341 ccgcgccgtt cgggcctaca agaacagtgc gctccccgcg ttccaccagc aggtccaggt
    11401 tttcataaac cctgcggtcg ccataggatt ggcagacttt ttccagctca atgactttct
    11461 gggtgctgcg cggaggctgg gggaagttga atttaaatac tttcctgcgg gctaccggtt
    11521 tttgaatgat tttcatcttt tccagctgct tgatgcggct ctggacttgc ccggctttgg
    11581 aattgatgga gcggaaacgg tcaataaatt cctgaatgtg cgctatttcc ttctgctggt
    11641 tgcggtaggc cgcctgaagc tgctcgaagc gcacgtcctt ttgttggagg aagtccgagt
    11701 aattgccgcg gtattccacc agttcttcgt tgtcgatgtc gtacacgctt tccaccagct
    11761 catccatgaa atcccggtcg tgggaaatca tcaggatggc tccggggtag tttttcaggt
    11821 atcgctggag ccacagcagg gacaggaggt ccaggtggtt ggtaggttcg tccagcatca
    11881 ggaggtccgg ctccaggaca aggagcttgg ccaggtacgc gcgcatgatc cagccgccgg
    11941 acatttcccg ggcggggcga tggaagtcgc tttcccgaaa ggccagccct ttgagaattt
    12001 tcttggcttt gggctccagc tggtaaccgt tggcggcgtt gaaagtgtca atggcttccg
    12061 cgtattccgg cgtatccgtt ttgttggcgt tttccgccgt ccggatggtg tggatggcct
    12121 gttccatttc cggcgtgatg cccagggcga tttccagaac ggtttcatcc ttcggttcgc
    12181 tggcttcctg gggaagatag cccacgatgg cgtattcatc catgctgatg gagccttcgt
    12241 ccggcgtgtc ttctcccaga atcatgcgga acagggtgga tttgcctgct ccgttggggc
    12301 caaccagagc cacccgttcc ccccagttaa tggtcatttc cgtttccctg aacaaggtcc
    12361 gtccggcgtg ggattttgtg agatttttga tcgtcagcat ggtgaagaga ggatgtattc
    12421 taccgggatg gaaaggggaa ggcaagagcc gtcagggcgg aggctggcat ttttgaaagc
    12481 tttactggat ttttacgcgt agtctgctag ccttggcgcg ccatgccgac cacgcagaca
    12541 ttcaggcttt tgcttgctgc cgcccttttg tgcggatgga gttcctgctg tactcctccg
    12601 gcggaggatt atatacaaca aacttacgtg cagcagcaaa tgtccgggct ggctaatgcc
    12661 ttcctggcgc tgctgccgcc ggatcaggcc tctcttcccg ctgccggagc ggaggccagg
    12721 tggctggcgg acacggccgt ggtccagtcc gcagcgattg cccgggacaa caggactgtg
    12781 ctgtttggct ggctgaacaa tattctggtc aattccaacc tgcgcgacag ggggctgtgc
    12841 tggcaggtcc agcaggattt gtaccgggac ctgcgccgcc gccccgtgaa gtatttccgc
    12901 atagggctga cgattcgaga ccgtggaacg ggcagggagc acagttgcgt gtatgtcaat
    12961 gccgcgggga agggattgca gggctccatt gttctggatg cctggaagaa ctgcgggcat
    13021 ctggtgacgc tgacccagaa ggaccgggaa ggcggcaaat gggaggagga ctggcgggaa
    13081 ccatttgttt ccaaggcctt tccggagggc cattcctacg gcatggaaca tcacctggtc
    13141 tggcccgggt gggccaggaa acgccccatt ctggttcagc ggatattcca gtccgatcag
    13201 cagaatgagg cgaaggcggc cgctgaataa aggggaagcc tgatccggca ggaaccggca
    13261 cacggtgctg cgccgcggcg gtttgcggta tccgccgttt ttaaggaaaa tcccggcgaa
    13321 tcggcaaatg gcggagggaa tccggactca gggcaaataa aaacgcactc agtgcgtaca
    13381 ccgagtgcgg attaattgga taatttgcta gtgttgcagg gcaaaacccc gctgcaaact
    13441 tacttgccct tggcctgcac aaccggagcg ggagcaggag cggtggtttg ctgttgctgc
    13501 tgctgctggg agcaggaagc gaccaggcaa gcggcgccgg cgatggcgag gatagcgatg
    13561 ttcttcataa ttcgaattaa atacagtgtt tgttaactac tggaacctcc gcatccacgg
    13621 aggtttgctg gcaccaatgt aaatggtggc aagtagaaat caagagattt tcttgttcca
    13681 tgtcacggca ttacagaaaa g
//
