LOCUS       c00138_gnlPro..        10474 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDGKNFLA_138.
ACCESSION   c00138_gnlPro..
VERSION     c00138_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:55:47
            Original ID  :: gnl|Prokka|MDGKNFLA_138
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10474
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10474
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[365:5544]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      366..5544
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..10474
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10474
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             3..359
                     /locus_tag="ctg138_1"
                     /transl_table=11
                     /translation="EIRIRDWSSDVCSSDLSSADSKDKVIDITDVTAASYQVGERVMVI
                     GETSMGMMAVTLAFIIPFVLLIVSLFAWMALIGNELYAALLSLAVLIPYYFVLWLNKTR
                     MKQHFSFTIKPINN"
     CDS             366..1247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 31.9; E-value:
                     5.3e-10)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_2"
                     /sec_met_domain="Fer4_7 (E-value: 2.4e-12, bitscore: 37.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.4e-10, bitscore: 28.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.4e-09, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 2.6e-09, bitscore: 26.7,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 2.3e-11, bitscore: 33.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3e-06, bitscore: 17.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAATEAEPMVAVV
                     RCNGSCANRPRINQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTYPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNTIIELNFPPRKPKAEEAP
                     KTVAAEAPKVTE"
     CDS             1272..2609
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_3"
                     /sec_met_domain="Fer4_10 (E-value: 1.2e-09, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 7e-17, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 2.5e-51, bitscore:
                     163.3, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.5e-30, bitscore: 94.9,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.4e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PIVAKGDMVKVGTKIAEPAGFVSAAIHSSVSGKVAKIDTVVDASGYAKPAIFIDVEGDE
                     WEETIDRSKTLVKECELSSEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEVMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             2616..3608
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.4e-121,
                     bitscore: 393.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAVHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             3635..4372
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_5"
                     /sec_met_domain="FMN_bind (E-value: 1e-23, bitscore: 73.6,
                     seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQXXXXIRDWSSDVCS
                     SDLRKVKQLLMTLITKKGGDSYE"
     CDS             4383..4949
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-70, bitscore:
                     226.9, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             4972..5544
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg138_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.3e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5803..6837
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg138_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 8.3e-53, bitscore:
                     169.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(7070..7894)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg138_9"
                     /sec_met_domain="GHMP_kinases_C (E-value: 7.4e-10,
                     bitscore: 28.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.5e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLSPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPANEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQEAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFRFKGRL"
     CDS             8093..9646
                     /locus_tag="ctg138_10"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             complement(9643..9828)
                     /locus_tag="ctg138_11"
                     /transl_table=11
                     /translation="MVGDKVAKNKGVFFVIFATYPYQNTTWLYSIKNNRPLDWSKSSGY
                     FHLTKRSFYSTQKMFF"
     CDS             9968..10474
                     /locus_tag="ctg138_12"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDI"
ORIGIN
        1 acgagatacg aattcgtgac tggagttcag acgtgtgctc ttccgatctt tcttcggcgg
       61 atagtaaaga caaagtcata gatataacgg atgttacagc tgcttcctat caggtaggag
      121 agcgggtgat ggtgatcggc gaaacgtcga tgggcatgat ggctgtaacc cttgcattca
      181 taattccttt tgtacttctg attgtttccc tgttcgcatg gatggcgttg atagggaatg
      241 aactgtatgc ggctcttctt tctctggcag ttcttattcc ttattatttc gtattgtggc
      301 tcaataaaac gcgaatgaaa caacattttt catttactat aaaaccaata aataactaaa
      361 acattatgaa tttgattctg attgcagtga tttcattggg agctatagcg ctcgtgctgg
      421 ccgctattct ttatgtagct tccaagaaat ttgccgtgta tgaagacccg cggattgccc
      481 aggtggggga agtgttgccc caggcaaact gtggtggatg tggctatcct ggttgtagcg
      541 gatttgccga tgcttgcgtc aaagccggtt cgctggatgg taaattctgc cctgtaggcg
      601 gtcagcctgt catggcacaa attgctgata ttctcggact ggcagctact gaagctgaac
      661 cgatggtagc agtagtaaga tgtaacggaa gctgtgccaa tcgtccgcgt attaatcaat
      721 acgacggtgc gaagagttgc gctattgccg cttcattgta tggtggagaa acaggttgta
      781 gctacggatg cctcggatgt ggcgactgtg tggctgcctg ccagtttgac gctatccaca
      841 tgaatcctga aacgggactt ccggaagtgg atgaagccaa atgtacagct tgtggcgctt
      901 gtgtgaaggc ttgtccgaag gcgatcatcg agattcgtcc gcaaggcaag aaatcacgcc
      961 gtgtgtacat ctcttgtgtg aacaaagaca agggagccgt agcacgtaag gcttgtacag
     1021 tgagctgtat cggctgtggt aagtgtgtca agacttatcc gttcgaagcc attacgctgg
     1081 agaacaacct ggcttacatc gatccgaaca agtgtaaatc atgccgtaag tgcgtggaag
     1141 tttgtccgca gaacacgatt atcgagctga acttccctcc acgtaaaccg aaggcggaag
     1201 aagcaccgaa aacagttgct gcagaagctc cgaaggtaac agaataataa cagaataaaa
     1261 tacagaattg tatgttaaag acattttcaa ttggtggagt tcatccacac gaaaataaat
     1321 tgtcggcaca tcaacctatc atcacagcgg aagttcctgc aaaggcagtt attctgttgg
     1381 ggcagcacat tggcgcacct gccaaaccga tagtagcaaa aggtgatatg gtgaaggtag
     1441 gcacgaagat tgccgaacct gccggcttcg tttcggcagc aattcactct tctgtcagtg
     1501 gaaaagtggc gaagattgat acagtagtcg atgcgagcgg ttatgcaaaa cctgctatct
     1561 ttattgatgt agaaggcgac gaatgggaag aaaccattga ccgtagcaag acactggtca
     1621 aagaatgtga gctttcgtcc gaagaaatcg tgaagaagat tgccgatgcc ggtatcgtag
     1681 gtttgggtgg tgcttgtttc cctacacagg tgaaactttg tccgcctcct tcgttcaagg
     1741 cagaatgtgt gattatcaat gcggtggaat gtgaaccgta tctgactgcc gaccatcagc
     1801 tgatgctgga acacgcggaa gaagtcatgg taggtgtctc cattctgatg aaagccgtga
     1861 aggtaaataa ggcatttatc ggaattgaga ataacaagcc ggatgctatt gaactgatga
     1921 cgaaagttgc ttccagttat gcaggcatcg aagttgttcc tttgaaagtg aaatatcctc
     1981 agggtggtga gaaacagttg attgatgcga ttaccaaacg ccaggtggca agtggtgcgc
     2041 tgcctatctc tactggggca gttgtgcaga atgtgggtac ggcatttgct gtttatgaag
     2101 ctgttcagaa aaataaaccg ttgtttgagc gtgtgattac cgtaactggc aagtctgtgg
     2161 ccaaaccttc caacttcctg gcgcgtatcg gtacaccgat gaaacagctg attgatgctt
     2221 gtggcggtct gccggaggat acgggaaaag tgatcggtgg cggtccgatg atgggtaagg
     2281 ctctggtgaa tatcgaagtt cctaccgcaa aaggcagttc cggtatcctg attatgaatc
     2341 agaaggaagc caaacgtggt gaagcacaaa cctgtatccg ttgcgcaaag tgtgtgagcg
     2401 cttgtccgat gggactggag ccgtacttgc tcggagcttt gtccgaaaac ggagattttg
     2461 aaacaatgga aaaagaaaga atcatggatt gtatcgagtg cggttcctgt cagttcactt
     2521 gtcctgccaa ccgtccgctg cttgattact gccgcttggg taagggtaaa gtaggagcta
     2581 tgattcgtgc acgtcaagct aaaaaataac gaagtatgga aaataaatta atcgtatcac
     2641 tatcacccca cgtgcatggc ggagacagcg tacagaaaaa tatgtatggc gtgctgatcg
     2701 cactgattcc ggcttttctg gtgtcgcttt atttcttcgg cctgggggct ctgattgtca
     2761 cggctacttc ggtagcagcc tgtttattct tcgaatgggc gatcgttaaa ttcttaatga
     2821 agaaacctgc tacaaccatt tgtgacggtt ctgctgtcat tacaggtgtg ttgctggcat
     2881 tcaatctacc ttccaatctg cctatctgga ttatcattct gggtgcactg ttcgcaattg
     2941 gtgtaggcaa gatgtctttc ggtggtctgg gctgcaaccc attcaacccg gcattggcgg
     3001 gacgtgtatt cctgttgctt tctttcccgg tgcagatgac aacatggccg gtagtaggtc
     3061 agctgacatc ttatatggac gctaccaccg gtgctactcc gctggcattg atgaaacagg
     3121 ctgttcacgg cgatgcaagt gctttgagcc agatacctga tgcgctgact ctgtttatcg
     3181 gacagaacgg cggatgtatc ggtgaagtaa gtgcgctggc actgttgctc ggactggtat
     3241 acatgctctg gaaaaagatc atcacctggc atattccggt ttctatcatt gtgactgtat
     3301 ttgtatttgc aggcattatg catatggtgg atcccgaaaa gtatgtttct ccggtattgc
     3361 aactactctc cggaggtctg atgctgggag ctgtctttat ggcaaccgac tatgtgactt
     3421 ctccgatgag caagaaaggt atgctgattt acggtgtttg tatcggtctg ctgacggtgg
     3481 ttatccgtct gttcggtgca tatcccgaag gtatgtcatt cgccatcctg attatgaatg
     3541 cgttcactcc gctgattaac acctattgta aacctaaacg ctttggggag gtagcgaaga
     3601 agaaatgaaa aagttacaat catctttaaa gaatatgttg ctggtactta cgggcgttac
     3661 agctgtttcc gtagcgttgc tggcttatgt gaacgaactg acgaaaggcc ctattgccga
     3721 agcgaatgca aagacgctga acgaggcctt gaaaaaggtg cttcctgaat ataccaataa
     3781 tccggtagcc gaaagcgata ctgttttcag cgagaaagac ggaaagaaaa tcgtggattt
     3841 cattatctat ccggccaaga atggcgaaaa gtgggtaggt tctgccgttg aagccaagtc
     3901 aatgggattt ggcggtgaac tgaaagtgct ggtgggcttt gatgctgaag gcaagattta
     3961 taactactct ttattggcgc acgctgaaac tccgggattg ggttcgaaag cggacaaatg
     4021 gtttggagct tatgatcctg caaagaacga aaaaccggta tctcacgaag aaagtgcaaa
     4081 gtctattttg ggcatgaatc cgggagagac tccattggct gtgaccaaag acatgaatgg
     4141 acaggtagat gctatcacgg cttctactat cacttcacgt gctttcctga atgcggtgaa
     4201 tgctgcttat caggcatata aaggcggtga ggtggatacg aattccggag cttcccagaa
     4261 nnnnnnnnnn attcgtgact ggagttcaga cgtgtgctct tccgatctcc ggaaggtgaa
     4321 gcagctgcta atgacactaa taactaagaa aggaggagac agttatgaat aattttaaag
     4381 taatgatgaa cgggattatc aaagagaatc ctatttttgt gctcctgctc ggtatgtgtc
     4441 ctacactggg tacgacatca tcggcaatca acggtatggg tatgggactg gccactatgt
     4501 tcgtcctgat ttgctcgaac gtggtaattt catctatcaa gaatctgatt ccggatatgg
     4561 tacgcatccc ttcatttatc gtggtgatcg cgtcattcgt gacactgttg cagatgataa
     4621 tgcaagcata cgtgcccgat ctgtatgcta ccctcggtct tttcattccg ctgatcgtag
     4681 taaattgtat cgtattggga cgtgcggaag cttttgcagc gaagaacaat ccgctggctt
     4741 ctatgtttga tggtatcggt atgggatttg gttttaccat tgccctgact ctgttgggtg
     4801 ccgtacgtga attcctcgga acaggtaaga tatttaatct gaccattctg ccggaagaat
     4861 acggaatgct gatctttgtt ttggctccgg gtgcctttat cgctttaggt tatctgattg
     4921 ccattattaa tagtctgaag aaagcctaac tctattaaat aagaaaagaa tatggaatat
     4981 atattgatat ttatctcggc aatctttgta aacaacattg tgttgtcgca gttcctggga
     5041 atctgtccgt tcctgggtgt ttccaagaag gtggaaacag cgatgggtat gagtgcggca
     5101 gttgctttcg tgctgactat cgctaccatc gtcacattcc tgattcagaa gtttgtgttg
     5161 gacgctttcg gattggggta cttacagaca atcactttta ttctggttat tgccggactg
     5221 gtgcagatgg tagaaattat tctgaagaaa gtttctcctt ctttgtatca ggcactgggg
     5281 gtgttcctgc cgttgattac aacgaactgc tgtattctcg gtgtggcaat cctggtaatc
     5341 cagaaagact ttgatctgct gacaggtgtt gtatatgcat tctctactgc tcttggcttt
     5401 ggtctggcac tggtattgtt tgccggattg cgtgagcaga tgaccctggt gaagattccg
     5461 aaaggaatgc aggggactcc gattgctttg attaccgcag gtttgctggc aatggcattc
     5521 atgggcttct ctggcgtcgt gtaaaagact aagttgataa ttagataaag aggctggaaa
     5581 ctctgtcgta tggcaacata caggcagttt gtttccggcc tttttcttta tatctgttca
     5641 taccgaatat gttttttatc ataccaaaac gccctcaaat cgtcccgtaa gtatcttcct
     5701 gtgaataaaa ttgcgatagt ttattgcatt tccattttat ttccatacat ttgtacctca
     5761 aacaaactga aaaccgaaaa actaaccata ttttaaaatt atatgaaaga aagaatttta
     5821 gtaacgggag gaacaggcta tattgggtct cataccgttg tagaactaca aaacagtgga
     5881 tacgaagtaa tcattatcga taatttatca aattcgagtg ctgacgttgt tgacaatata
     5941 gagaaagtat ccggtatccg cccagctttt gagaaactgg attgtcttga ttttgctggc
     6001 cttgatgccg tatttgccaa atataaagga attaaagcga ttattcattt cgcagcaagc
     6061 aaagcagtag gagagtcggt agagaagccg ttgctttatt atcgtaacaa cctggtttct
     6121 ttaatcaacc ttctggagtt aatgcctaaa catggagtag aaggcatagt gttctcttct
     6181 tcctgtacag tatatggtca accggatgag ttgcctgtaa cggaaaaggc tccgatcaag
     6241 aaagcggaat ctccttatgg aaatacaaaa cagattaatg aagaaattat ccgtgataca
     6301 atagcttccg gtgccccgat caatgctatt ttgctgcgtt atttcaatcc gattggcgca
     6361 catcctacag cattgctggg tgaacttccg aacggtgttc ctcaaaacct gattccttat
     6421 ctgactcaga cagcgatggg tatccgtgaa aaactaagtg tattcggtga cgattatgat
     6481 actcctgacg gttcttgtat ccgtgacttt atcaacgttg ttgacttggc taaagcacac
     6541 gtgattgcaa tccgccgtat tttggagcaa aaacagaaag aaaaagtaga agtattcaat
     6601 atcggtacag gacgcggtgt ttcagtattg gaactgatta atggctttga aaaagctact
     6661 ggcgttaaac tgaattatca gattgtaggc cgtcgcgcag gtgatattga aaaggtatgg
     6721 gctaaccccg attttgccaa ccaggaactg ggttggaaag cggtagaaac attagaagat
     6781 actttacgct ctgcatggaa ttggcagctg aaactccgtg aaagaggcat tcagtaaaaa
     6841 gatatttgtt ttaattaaca taaaagttta aacaaatcgt tcatgcgatt tgtttattag
     6901 atgctaatca gcttgatctg tttgtgagta tgtgaatatg agtaaatggt acttatgcct
     6961 ctccggcata gacaggtatg attgcatagt agttttgtcg tgttttattt tgtgtttgtg
     7021 ttgtgacggt actacgacgg gagtcgtggt accgtttttt gttactcctt tacagcctgc
     7081 ctttaaaacg gaatacgtta gttccccaat cggtttcagg taaagttcct tccggctcga
     7141 acaatccata tacggaagaa ccggaaccgc tcatagaggc ataaacagcc tcttgcctgt
     7201 atagttcggc tttaatttct ccgatcaccg gatgctgggg gaatacgctg tcttcaaaat
     7261 cattgattaa tatctctttc cattcatttg ccgggcgttt gatcgcttct ttgatcgagt
     7321 attcgggatg atgagggtga atattggcga aagcttcccg cgttgatacg aatacatccg
     7381 gtttgatgat cagaatctga tatcctttta aggatagtgg aatgggggag aatatgttgc
     7441 cgattccttc ggcaaaggtc ggggcgtttc tgataaagaa agcgcagtct gctcccaaag
     7501 ttgcggcata tatttccagc tgatcttcgg ataaattcag ctgaaagtgt tcgttgagta
     7561 atttcagcat gaaagctgcg tctgatgagc ctcctcccag tccggcaccg gaaggaatgt
     7621 gtttgtacag atggatctcg ataggagaga ggtgaaactc tttatctaat agcagatatg
     7681 ctttcaccac taaattgtct tctggattac cggatatctc cattccgtac tgatgcaggg
     7741 agaacttttt gtccgcttcg gggctggtcc ggatttccag cgcatcttcg agagcgacgg
     7801 ggtagaatac ggtttcgagg ttgtgatatc cgtccggacg cttctcggta atagagagtc
     7861 ccaggtttat ttttgcgttt gggaaagtga tcatattcgt tctgaattat tatttttgaa
     7921 ttttaaatta tgggttgcga atttatgcta ttggtgacaa agttactaaa atcttcattt
     7981 ttccttatct tttcttcatt attatattct atctttgtca tccctttcgg attttactat
     8041 gtataaaagc cggggatcat aaattgtaaa tcataaaatt gtatataagc agatggctga
     8101 acaaagaaga aattcccgta acacaaaatc aactaaagta caaccggtca atgattatgg
     8161 tcgtatccaa cctcaggcac cggagctgga agaggcggtg ttgggtgctt taatgattga
     8221 gaaggatgct tattcgctgg tgagtgagat tcttcgcccg gagtcatttt atgagcatcg
     8281 tcatcagttg atttatgctg ccattactga tcttgccgtt aatcagaagc cggtggacat
     8341 tctgacggtc aaagagcagt tgagcaaaag aggtgagttg gaagaggtcg gtggaccgtt
     8401 ctatattact cagttgagca gtaaggttgc ttcttccgca catatcgaat atcacgcccg
     8461 tattattgca caaaaatcgt tggcgcgcga attgataacg tttaccagta atattcaaag
     8521 caaggctttt gatgagacac tggatgtgga cgacttgatg caggaggcgg aaggcaagct
     8581 gtttgagatt tcccagcaga atatgaagaa agactatacg cagattaatc cggtaattga
     8641 cgaagcgtat aagctgattc agaaagcggc tgcacgaacg gacggtctga gtggtcttga
     8701 aagtggattt acgaaactgg acaagatgac ctccggttgg cagaactccg accttattat
     8761 aatcgctgcc cgtcctgcca tgggtaagac agctttcgta ctttctatgg ctaagaatat
     8821 tgctgttgat tatcggaatc cggtagcgtt gttctctctt gaaatgagta acgtccagtt
     8881 ggtcaaccgt cttatcacca atgtttgtga gattccgagt gagaagatca aaagtggaca
     8941 attggcaagc tatgagtggc aacagttgga ctacaaactg aaagacctgc tggatgctcc
     9001 gctttatgtg gacgatactc cgtctttgtc tgtgtttgaa ctccggacca aagcacgtcg
     9061 tctggtgcgt gaacatgggg tgagaatcat tattattgac taccttcagt tgatgaatgc
     9121 gagtggtatg gcattcggta gccgtcagga agaggttagt acgatatccc gttcgttgaa
     9181 aggattggca aaggagttga acattcccat tatagccttg tcgcagttga atcgtggtgt
     9241 ggagagtcgt gaaggtattg acggtaaacg ccctcagttg agtgaccttc gtgaatccgg
     9301 agccatcgag caggatgccg atatggtgtg ttttattcac cgtccggaat attataagat
     9361 ttatcaggat gatcgtggta acgacctgcg cggtatggcg gaaattgtga tagccaagca
     9421 tcgtaatggt gcggtaggtg aagtcttgct ccgattcaaa ggtgagttta cacgattctc
     9481 taatccggaa gatgatatgg ttataccgat gccgggtgaa cctgcaggtg ccatgctggg
     9541 gtctaaactg aatgccggtg ctatgcctcc gcctccgccg gaaccggact ttgttccgca
     9601 gggaaataat ccgttcggtg caacggaagg accgttacct ttctaaaaaa acatcttttg
     9661 ggttgaatag aatgaccgct tagtcagatg aaaataaccg ctcgatttac tccaatcgag
     9721 cggtcgatta ttttttatag agtatagcca agttgtattc tgatagggat aggtggcaaa
     9781 aatgacaaag aatacccctt tgttttttgc cactttgtca ccaaccatga atttattggg
     9841 gaataataca gtcaggtcct tgttagttta gcttctcttg acatttttct ctcaaatcgt
     9901 tctatgtcaa ccgaaaaatc ttattaactt tgcgaaactt tttgagaaac aataaaaatt
     9961 taattatatg aatatctctt ataactggct gaaagagtat gtcaactttg atttgacccc
    10021 cgatgaaacg gctgctgcgc tgacctcaat cggcttggaa acaggtggtg tagaagaagt
    10081 gcaaaccatt aagggtggtt tggaaggact cgtaatcggt gaagtgctga cttgcgaaga
    10141 acatccgaat tccgaccatt tgcatatcac taccgtcaat ctgggagacg gcgaacctgt
    10201 acagattgta tgcggtgctc cgaatgtagc tgccggacag aaagtagtgg ttgccacttt
    10261 gggtaccaaa ctttatgacg gtgatgaatg ctttactatc aagaagtcaa aaatccgtgg
    10321 tgtagaatct acagggatga tttgtgcaga agacgaaatc ggtattggta ccgatcatgc
    10381 aggaatcatc gtgttgccgg ctgaagctgt tccgggtact ctcgccaaag actattataa
    10441 tatcaagagt gactacgtac tcgaagtaga tatt
//
