LOCUS       c00002_gnlPro..        13796 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFKMDIFJ_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:40:45
            Original ID  :: gnl|Prokka|BFKMDIFJ_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13796
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13796
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[306:3796]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      307..3796
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13796
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13796
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(307..1074)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.8e-22, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6e-10, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.4e-05, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1115..3073)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.3e-53, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.4e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3095..3796)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-12, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3997..4269
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4302..5087
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5121..5354)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5786..6493)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             7011..8084
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_8"
                     /sec_met_domain="NAD_synthase (E-value: 4.8e-09, bitscore:
                     30.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VARILVGLSGGVDSSVAAALLVEQGHDVVGAYMKNWVNDEGIPGE
                     CPWEQDIQDALAVAKTTGIEFRVIDLVDEYRARIVNYLIEGYRAGYTPNPDVLCNREMK
                     FGVFLDYALEQGFDYVATGHYARRMDTPQGAFILRGRDPNKDQSYFLSLMRPDQIARAV
                     FPLGDLLKPEVRVLAEKYGLPTARKKDSQGICFIGQVKMSDFLRHYLPDKPGKIVDTEG
                     RTLGTHNGLHLFTMGQRKGHGVASPREGVAYVVVGKDVQRNRLILGYEDASTRGLYASR
                     AVVGGISNTLAPLPARVMAQPRYRAKAEWASCEYLEEGKVRLGFDTPLRALAVGQVCAF
                     YDGGKLLGGGFFESIEP"
     CDS             8081..9430
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MTDPERTIAAQATAAGQGAIAVIRMSGPGCMDILKQCTPAAFTER
                     LRPRRATLVCIRDAEGAAIDQALVTWFPAPASYTGEDTAEISCHGGMLVTDRLLKRLYQ
                     CGASPAEPGEFTKRAFLNGRMDLTQAEAVMDVISAGSDLALKAAQTQLDGGIGAQVDEL
                     KDNLVHVLAHIEAYIDFPDEDISPDTASDLLARLRSMEEKLTALLKTAEGGRLLREGIR
                     TAIAGPPNVGKSSLLNTLLGYDRAIVSNIAGTTRDTVEESIQLAGLALRLIDTAGVRES
                     SDVIEQAGITRTNRALETADLVLEVADASTPRIQDFPAPVLTAPRLLILNKCDLGVHPD
                     WKAVPGIRFSCATGEGRKELEEAIIQAFSSSLPGETGSSLVAINARHQHELGLCREHVR
                     LASESISRQESPEFTALELREALTHLGEITGAVDTEDVLGAIFSSFCLGK"
     CDS             9575..10432
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MLRTLSLFFLFALVPVQAAIYFAHNVSEDSGFINTKKYWNGDSDL
                     CWAATASNMLQWWQNNSSGIPAFVPNGQNESGRTEIYDVFCNNWANTGKGIEIGLRWYL
                     GGKPLNPNNYLYDFKETITEPQNTGRYWEGYITSLGLSSSTWEGDCPFISSKYFTQSDF
                     PLQFGTDLVSFFQNGGVVGLSIAPASGPGHAITCWGIEVDDTTGMAKSLYVTDSDNGQG
                     LEKRDVYYHETDGTLHLGSKNGPRINAYDALMLPFHNVPEPSTAVLTTLAAGTAFCRRR
                     RRRS"
     CDS             complement(10458..11111)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MFLSTCEIMSTIIGALAGSIASSRVKMDLFGVIVCGTLAALGGGT
                     VRDILLDIPVYWTLPSGEIFVLASVVTSLATFYVAQKYPPPMGTIRVADAIVLALFGMI
                     GTEKSYLHGYTPTVSVMMGICTGVAGGLLRDVLTGNVPYVFRPGELYATAALLGGVAYA
                     VLYYAGIDSSTCFVTGFMVTLSVRLAAIRWNWNLPSYIPLFTSDTDSPPEEPET"
     CDS             complement(11140..11991)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MFPCHKKKHGYGLAPFRGRYYIPRMMQFCVLGSGSGGNATIVRAG
                     ETVLLVDAGFSAARLRDKMKSAGVEPDELDAILLTHEHADHMKGVHQFTRKHAVRVYAT
                     RHTAMCVQEKAPEAPWAYFEKGQSFRIGDIVITPFPTYHDAVDPVGFKFETERSSLGFI
                     SDTGQAPGCIAEYLAMVDSLVVESNYDPDMLAATPRRPWPLKQRIASAHGHLSNEQACD
                     LLRRIAHGALKNVVLAHLSAESNSPALAESLMRDTLHDMGLASTSLFCASQDSCLPWIR
                     VC"
     CDS             12077..12532
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MSSVSDNLFGAYTHKLDPKNRIAIPAEWRPSEGCALLLLSGRRLD
                     LPTVKAYTREKFQQLIDKIETTPGYTEAQIDLFIGKLYANCVEAVINAQGKLLIPKQMC
                     EHAQLSSSVRLAARRGYFELWEPSLYEEVSRRENASISDINQSYGIL"
ORIGIN
        1 cttgacagga tgccatccct tccgggcatc agtccaattc ctgtaatcaa tgtttctttc
       61 tctcgaagaa agatgggggc cgtcgctgtc ggacgggggc ttgcttaggt ttcgtccggc
      121 atttccaagt acggtctcct ggattactgg aacccttccg gtgtaacaat tttttacgct
      181 gcgcgacgat gaggaagcaa ctgtctggta ttttattcct ggttcaagga aacctggtaa
      241 tgaaaaaact cccgacagcc gatgccgccg ggagttttta cagagcgtct taagaaggaa
      301 tcttctttag aaacagaggc cttccttggc gttggcccgc atgaagtcgc ggttgaggcg
      361 ggcgatgttg tccacgctga tgcctttcgg gcaggcggct tcacattcat actggttcgt
      421 gcagttgcca aagccttccg cttccatctg cttcatcatg gccaggacgc gcttggaacg
      481 ttccggctgg ccctgcggca gcagattgag atgggcgatc ttggcggagg tgaacagcat
      541 ggcggaggcg tttttacagg aggccacgca ggcgccgcag ccgatgcagg cggccgcgtc
      601 aaaggcggcg tccgctttca ctttttccac ggcgatgttg ttggcgttcg gcgcggaacc
      661 ggtacgcacg tcaatatagc ctccagcggc gatgatgcgg tccagggcgg agcggtccac
      721 catcaggtcc cgcaggattg ggaaagcctt cgcgcggaag ggttcaatcc agacggtatc
      781 gccatccttg aacttgcgca tgtgaagctg gcaagtggtc acctggcgtt ccggcccgtg
      841 gggaatgccg ttgatggtca gggagcacat gccgcagatg ccttcccggc agtcgtggtc
      901 aaaatggatg ggttccttgc cttccttgac caggccttca ttgacgatgt ccagcatttc
      961 caggaaggag gcgtccaccg gaatgtcctt ggcggcatag gtctcaatgc ggcccttggc
     1021 ttcccggttt tcctggcgcc agaccttgag agtgagattg agtgttttag ccatgttata
     1081 atctttcttt tgagtgttaa tgtattggct atctttactt gtagctgcgg atggcaaggt
     1141 gcacgttctc gaaggtcagc ggttccttgt ggagaacagg caggctgtcc acgccagtgt
     1201 attcccaggc ggctacatag gcgtattcat cgtcgttgcg cttagcttcg ccgtccggca
     1261 gctggtattc cacgcggaag tgggcgccgc aggattcctg gcggttcagg gcgtcatagc
     1321 agagcagctg ggcgaattcc aggaagtcgg ccacgcggca ggctttttcc agttccgcgt
     1381 tgatgccgtc cgccgtgccg gttacgcgca cgttttccca gaattccttg cggagctggg
     1441 gaatgcgttc aatggcgtgg gtcaggcttt cttccgtgcg ggccatgccg cagtcttccc
     1501 acataatgag gcccagttcc cggtggaagg agtccaccgt cttggtgccc ttcacattca
     1561 ggagcttgtt gatgcgttcc ttcacttcgt cttccgcagc cttgaattcc ggggcggcgg
     1621 tggtgacggc gccgggtttg gtggtcgtca ggtaagcggg cagcgtggcg ggaatgacga
     1681 agtagccgtc agacaggccc tgcatcaggg cggaggctcc caggcggttg gcgccgtggt
     1741 cggagaagtt ggcttcaccg aggacgtgca gccccttcac attggacatg aggttgtagt
     1801 ccacccacag gccacccatg gtgtagtggg aggcggggta gatcatcatg ggcgtttcat
     1861 gggggtcgtc gtccgtgatt tcttcgtaca tgtcaaacag attgccgtat tggccgtcaa
     1921 tccattcgcg gcccatgcgc ttgatttcat ccgcaaaatc taggaagacg cccttgccgg
     1981 tgacggccac gccgcggccg tcgtcgcagg cttccttggc ggcgcgggag gaaatgtcgc
     2041 gcggagccag gttgccgaag gagggatact tgcgttccag gtagtagtcc cgttcttctt
     2101 cgggaacatc ggaaggcttg atttcctttt tacggatttt ttctgcggtt tcacgggact
     2161 tgggcaccca gatgcggcca ctgttgcgga gggattccga catcagcgtc agtttggact
     2221 gatagtcgcc cttgaccgga atgcaggtgg ggtggatttg cgtgaagcag gggttggcga
     2281 agaaggcacc gcgcttgtag gccttgtagg cggcagtgac gttgcagccc atcgcgttgg
     2341 tggacaggaa gaacacgttg ccgtagccgc ccgtgcagag caggacggta tcccctgcgt
     2401 aggatttgat ttcgccggta accagattgc gggtgacgat gcccttggct tcgccgtcca
     2461 ccagcaccag atccatcatt tcatggcggg agaacatttc aatgtgtccc ttggccactt
     2521 ccttttccag ggcctggtag gcacccagca gtagctgctg gcccgtctgt ccgcgtgcgt
     2581 agaaggttcg cttgagctgg gcgccgccga aggagcggtt gtccagcagg ccgccgtatt
     2641 cacggccgaa gggaacgccc tgggccacac actggtcaat gatgttggag gagacttccg
     2701 ccagacggta gacattggct tcacgggcgc ggaagtcgcc gcctttaacg gtgtcgtaaa
     2761 acaggcggta aacggagtcg ccgtcgttct ggtagttctt ggctgcgtta atgccgccct
     2821 gggccgcaat ggagtgggcg cggcgggggc tgtcctggta gcagaagcat ttgacgttgt
     2881 agccaagttc ggcaagcgtg gcggcagcgg aggcgccagc caggccggaa cctaccacaa
     2941 gcaccgtgta cttgcgcttg ttgttcggat tgatcagttt ggactcaagt ttgtacttgg
     3001 accatttgtc ctgaataggg ccggagggaa ttttggcatc cggcatccag tcgcttacgg
     3061 gaaaattaat catgactttg agaggagttg atggttattt gatgataccc agaagaaccg
     3121 agaccggcac ggagatgaag cccaggcaga taatcgcgcc gtaggcgatg gcgataaagt
     3181 tgtagaaggg ccggattttg cgggaatcga cgcccacagt ctggaagatg gactgtaccc
     3241 cgtggcgcag atggctgaac agcatcagaa cggccaggat gtagaaggcg gagcaccata
     3301 cgttggagaa tccggtcacg atcatcttgt acacgtcaaa ggtttccacc gtaccgtcgg
     3361 aaatgaaggt ggtgaactgg gcggggtcgt atcccacgcg cagggtgtac tggtacaggt
     3421 ggtagatcag gaacaccagg acggtcaggc cggtatagat catgtagcgg gaggagagcg
     3481 tcgccttgat ggtgttcttg aacacgtagg gttcgcgggc cgcatggttt tccagcttca
     3541 gctggatggt cagccagacg tggatgatga agatcaccgc aagccccgcg cggattcccc
     3601 agagggctgc ttccggcatg gagtgcaggc cgtgggcgta ggtgttgatc cattcagggc
     3661 ctccgaagat gagaaggttg cctgccaggt gtcccgcaag gaacaagacc aaacataacc
     3721 ccgtcagagc cacaatgatt ttgcggccga tggaggatgt cacgaatgta catatggttt
     3781 ttactagtgc attcataggc gctctaatga aataaatgcg tcttcacagg atgcctggtt
     3841 caagcccgga tggcaagcct cttcttgaat ttccggcgct tttcggattt ttgaaaagcc
     3901 ggggaaagat gttgctgttt atcagtttgg aatggttatc attttgttgc ctgttccggc
     3961 ttgacgaggc tttccgcata ggcgtatcgt ctgtgcatga aaagaagtaa aaaggaagtg
     4021 ctggacgcgg atttcgcagc ggcgcgcgcc ggcgttctgg atgtggccgc atttctggac
     4081 cgggtggacc gcggggaagg ggaggcggat ttccgctacc atgccctgat ggatgttctt
     4141 cccctcttat ccgcatccgg ccccggacgc gtccgggcca tcctggaagc cctttcctac
     4201 agggatgaca ccgtgccgga aaccgccgca gccaaagcgg cctgcggagc cccgaacctc
     4261 agcaaataag aatgatggct ttcatagaac ctcatataca tatggtgtgc cgcaccacgg
     4321 acgaataccg ggccatggcg caggccggct gcctggcggt aggggaaccg gcgttctggg
     4381 ccggttacga ccgttcgtcc gcggacggtt tccgggatta tttcgtacag cttacggaat
     4441 gcgaacccgc cagggcggcc aagttcggca tggaccatta cacatggctg tgcatcaatc
     4501 ccaaggaggc gcaggacgtg gctttcgcgc gggatgtgat gaagctgatt ccggagttca
     4561 tcgaccggcc caatgtcctc ggcatcgggg aaataggact gaaccggaat acttcccatg
     4621 aaatgactat ttttgaagag catctggatc tggcggtgcg cctcaaccag cttgtgctga
     4681 ttcacactcc ccatctggaa gacaagctta aggggaccgt aatgattctt tccgccctga
     4741 aaaaccgtcc ggatctggac ccttgccgcg tgctggtgga tcactgtgag gaacatacct
     4801 tcccgctggt gaaggaggcc ggttactggg ccgggctgac cctttatccc accagcaagc
     4861 tgaatcccaa gcgggcggcg gatattctgg aattgtacgg aatggaccgt gtctgggcca
     4921 attccgcggc ggactggggg gattccgatc ccctggcgct gacggccctg gcctgcgagc
     4981 tgcgcaggcg cggtttttcc cggcaggaaa cggaacgtct tctcctggaa aatccggaga
     5041 cattcatggg acagtccccg aagttccgga aagtgtcgtc ccgctaattc cgcccgaggc
     5101 gcggcggagg gtacggccct ctagtccccg tccgggaaaa agacggtgag gacggcgccc
     5161 aggatgaccg ccgcgtcatc cagaaggccc agcctgccga ttccgtcaaa caggaattcg
     5221 tcgggagtca ggatgtaggc gccggcggcg gccagaaggc atatattccg tttgttgaaa
     5281 aaacgcggtt ctccttttct gcttttgaaa taccggaaca ggcgcagtag cagctgctgt
     5341 ttttgaaggt tcatggacgg gaacggggga taaaggttca agctcagcca ttttcccact
     5401 ccttttccct gtttcgggga aggagtctgt tgccgacgga cggaaaccgc agcgatccgg
     5461 accgtgcggg gaaatggatt gctgaaagga tgggctgttc cggatgctga gggaagccgg
     5521 gctttgcatg ctccggttcc ggctgtcccg gcatgggaaa aaggggcgtg tacggaagtg
     5581 gggcggggcc ggaagctctt gaaatgaccc tcccggggga gcctgaatgc catttccccg
     5641 tcaagtgctg gccgtgaggg taccgcagca aatggaagct tcttcccccc tgttttttcc
     5701 ggcagatgtt tgaacggata aggaaaaggc cggctcacga ttttgtgagc cggcctttga
     5761 atatagggag gcggacggta caggcttatg ccctgcggcg gcgcatcatc agcgcggcca
     5821 gtcccagcag gcccagggaa gccgtggcgg gttccgggat gctggcgatt tcactcatca
     5881 gttgaccaac ttgttcctgg gaaaggaggg agtcgtgaat gtagagctgt tcgatggatt
     5941 cagccagtcc tgcgtccatg agaatctgat caatttgctg gttgccgaat ttcaggccgc
     6001 tgttggaata gtacgtagtg ctgtctccaa aatagatgcg ggtgccaaga tctccggtga
     6061 ctacggaaat ggtcagggaa ccttccgtgc ccagcggggt gtcaacgaca ggcccgctgt
     6121 aggaggtgtt gttccataat ccctggagtt tccggtccgt gttcaggccc acgccccagc
     6181 ttacactgct gtttttggcg ttaaacagag cggtataggc gtccggagtg ttgattttgg
     6241 acaggtcaag aaccatcgtc acagacataa cgtcgcggtt gttggcaccg tatccgttga
     6301 aggttatccc ggataacgtc agattgctgt cgtcagacgt gatggaaacg gaatctttca
     6361 gggtgccgaa atccgccgtt tgggaggcaa agtccgaata tcccacgatg gagctatcca
     6421 gcagagaggt agccgcggta gcgcttaggc tcatgccgac cgaaagaatc agggtggata
     6481 ataatttatt catggtcagt atcttaataa aatgatgcaa gattcaatgt atgtacttgt
     6541 gcttgaataa cgaatttgga atccgtagct tttttccagg tggcctccgt tctccggcag
     6601 actgaaatca tcagaccacc gcattctgaa aaactgaata tgccattgaa caacaatttt
     6661 ttagttaata cctcctcatc tttcctcatc acggaaatac ctcctgaaaa aaaatgaagg
     6721 gccttacctc tccatattcc agcttcctgt ttaaagaggt ggtaaattaa ttataatact
     6781 tttttctaat ttattatatt gactacggat tccaaattcg atttcaggga atgtgattaa
     6841 aaatcaaaag cctcccggat cgaccgaatc atattccgca tcagggaccg gatgccccat
     6901 ttccacgctt tttgtcttgg cttacggaaa catctttggt ttacaggggc aggcggcaaa
     6961 gcctttctca aagcggtccg ccttatcacc cccatatctt ttccagcatc gtggcacgca
     7021 tacttgtagg cttatcaggc ggagtggaca gctccgtggc agcggccctg ctcgtggagc
     7081 agggccatga cgtagtgggg gcctacatga aaaactgggt gaatgacgaa ggcattcccg
     7141 gcgaatgccc gtgggaacag gacattcagg acgctctggc cgtcgccaaa acaacaggta
     7201 ttgaattccg ggtcattgac ctggtggacg aataccgcgc ccgcatcgtg aattatctga
     7261 ttgaaggcta ccgcgccgga tatacgccca acccggacgt attgtgcaat cgggaaatga
     7321 aattcggcgt ctttctggat tatgccctgg aacaggggtt cgactacgtc gccaccggcc
     7381 attacgcccg caggatggac acgccgcaag gggctttcat cctgcgcggg cgggacccga
     7441 acaaggatca atcctacttc ctgtccctga tgcgcccgga ccagatagcc cgcgccgtct
     7501 ttccccttgg ggatctgctg aaaccggaag tgcgcgttct tgcggaaaaa tacggcctcc
     7561 ccacggcacg caagaaagac agccagggca tctgtttcat cggccaggta aaaatgagcg
     7621 atttcctgcg ccactacctg ccggacaagc ccggcaaaat cgtggacacg gaaggccgga
     7681 cgctcggcac gcacaacggc ctgcatctgt tcaccatggg ccagaggaaa gggcacggcg
     7741 tcgcctcccc gcgggaggga gtcgcctatg tggtggtggg aaaggatgtc cagcgcaacc
     7801 gcctgattct gggatacgaa gacgcgtcca cgcggggatt gtacgcgtcc cgcgccgtgg
     7861 tcggcggcat ttccaatacg ctcgctcccc tgccggcccg cgtcatggcc cagccccgct
     7921 accgggccaa ggcggaatgg gcctcctgcg aatatctgga agaaggaaag gtgcgcctgg
     7981 gctttgacac gcccctccgg gccctggccg tgggacaggt ctgcgccttt tacgacggag
     8041 gcaagttgct cgggggcggc ttttttgaat ccatagaacc atgactgacc cggaacgcac
     8101 catagccgca caggccaccg ccgcaggaca gggagccatc gccgtcatcc gcatgagcgg
     8161 tcccggctgc atggacatcc tgaaacaatg cacccctgcg gctttcacgg aacgcctccg
     8221 tccgcgcagg gcgacgctgg tctgcatccg ggacgcggaa ggagccgcca ttgaccaggc
     8281 gcttgtcacc tggttccccg ccccggccag ttatacgggg gaagataccg cggaaatctc
     8341 ctgccatggc ggcatgctgg tgacggaccg cctgctgaaa cgcctctacc aatgcggggc
     8401 ctccccagcg gaaccgggag aatttacaaa aagggccttt ctgaacgggc gcatggacct
     8461 gacccaggcg gaagccgtga tggatgtgat ttccgccggg agcgacctgg ccctgaaagc
     8521 cgcgcagacc cagctggacg gaggcatcgg cgcccaggtg gacgaactga aagacaacct
     8581 ggttcatgtg ctggcccaca ttgaggccta tattgatttt ccggatgaag acatttcccc
     8641 ggacaccgcc tccgatctgc tggcgcgcct ccggagcatg gaggaaaaac tgaccgccct
     8701 cctcaaaact gccgaaggcg gacgcctgct gcgggaaggc atccgcacgg cgatcgccgg
     8761 acctcccaac gtgggaaaat ccagcctgct gaataccctg ctgggatatg accgggccat
     8821 tgtcagcaat attgccggta ccacgcggga cacggtggag gaatccattc agctggccgg
     8881 gctggccctg cggctgattg atacggccgg tgtccgcgaa tcttccgacg tcattgaaca
     8941 ggcaggcatt acccgcacca acagggctct tgaaaccgcg gatctggttc tggaagtggc
     9001 ggatgcctcc acgccccgga tccaagactt ccccgcccct gttctcaccg cgccccggct
     9061 gctcattctg aacaagtgcg acctgggagt ccatccggac tggaaggccg tgcccggcat
     9121 ccggttttcc tgcgccaccg gggaaggaag aaaggaattg gaggaagcca ttatccaggc
     9181 cttttcctcc tccctgcccg gtgaaacggg cagctccctg gtagccatca atgcccggca
     9241 ccagcatgaa ctgggcctct gccgggagca tgtccggctg gcttcggaat ccatctcccg
     9301 ccaggaaagt ccggaattca cagccttgga actgagagag gccctgacgc acctgggaga
     9361 aatcaccgga gccgtggata cggaggacgt gctgggcgcc attttttcct ccttctgcct
     9421 ggggaaataa gaagaagctt ccatcaacag gtttttctga ctccagattc ttctttcctc
     9481 tccattctgt ggaaggatgg caatcatcca aaaatttatt tgcggatatt ttcattgatt
     9541 ccggcttgtt aattcgctat cgatatcatg ttttatgttg cgcacccttt ctctcttttt
     9601 ccttttcgct ctggttcctg ttcaagccgc catttatttt gcccataatg tttccgaaga
     9661 ttcggggttc ataaatacca aaaaatactg gaacggagat tccgatttat gctgggcggc
     9721 cacagccagc aatatgctgc aatggtggca gaataattcc tccggcattc cggctttcgt
     9781 tcccaacggc cagaatgaaa gcggaagaac ggaaatttac gatgtgtttt gcaataattg
     9841 ggccaatacc gggaaaggca tagaaatagg cctgcggtgg tacctgggag ggaaacctct
     9901 caatcccaac aattatttat acgattttaa ggaaaccatc actgaaccgc agaatactgg
     9961 ccgatactgg gagggataca ttacatctct gggattgtcc tcttccacct gggaaggcga
    10021 ctgccctttc atcagcagca aatacttcac gcaaagcgat tttcccctcc agttcggtac
    10081 agacctcgtc tcatttttcc agaatggcgg cgtagtggga ctttccattg ctcctgcatc
    10141 aggtccgggt catgccatta cctgctgggg aattgaggtt gacgacacta ccggcatggc
    10201 caaatccctg tacgtcacag actccgacaa cggacaaggt ctggaaaaac gggacgttta
    10261 ttatcatgaa acggatggaa ccctgcactt ggggagcaag aacggccctc gaatcaacgc
    10321 atacgacgcc ctgatgctgc cctttcataa tgttccggaa ccttccacgg cagttctcac
    10381 caccctcgcg gcgggaactg ccttttgccg ccgcaggcgc cgacgctctt aaggcttcac
    10441 ggaaacattc cctcctgtca agtttccggc tcttcaggag gcgaatcggt atccgaggtg
    10501 aataacggaa tgtaggaagg caggttccag ttccagcgga tggccgccag gcgtacggaa
    10561 agcgtgacca tgaagcccgt cacgaagcag gtggaagaat caattccggc atagtaaagc
    10621 accgcgtacg ccacgcctcc cagcagggcc gcggtggcgt ataattctcc gggacggaac
    10681 acgtagggaa cgttgccggt aagcacgtcg cgcagcaggc cgcccgccac gccggtacaa
    10741 atgcccatca tcacggaaac agtgggcgta tagccgtgga gataggattt ttccgtgccg
    10801 atcatgccga agagagccag aacgatagca tccgccacgc ggatagtgcc catgggaggc
    10861 ggatatttct gggccacata aaaggttgcc aggctggtga cgacagaggc caggacaaaa
    10921 atttccccgg aggggagcgt ccagtacacc ggtatgtcca gcaggatgtc gcgcacggtt
    10981 ccgccgccca acgcagccag ggtgccgcag acaatcacgc cgaacaaatc cattttcacc
    11041 cgcgaggaag cgatggaacc cgccagggct ccaataatcg tgctcatgat ttcacaggtg
    11101 gagaggaaca tggcgggagg aacaggaaaa aaggcatatt cagcagaccc gtatccacgg
    11161 caggcaggag tcctggctgg cgcagaacag ggaggtggaa gccagcccca tgtcatgcag
    11221 ggtatcacgc atcaggcttt ctgccaatgc cggagaattg ctttctgcgc tcaggtgggc
    11281 cagcaccacg tttttcaggg ctccatgggc aatccgcctc agcaggtcgc acgcctgctc
    11341 attggacaga tgcccgtgcg cagaggcgat gcgctgcttc agcggccaag gcctcctggg
    11401 agtggccgcc agcatgtccg gatcatagtt tgattccacc accaggctgt ccaccatggc
    11461 aaggtattcc gcgatgcagc cgggagcctg ccccgtatcg gaaataaaac ccaggctgga
    11521 tcgctccgtt tcaaatttga atcccaccgg atccacggcg tcatggtaag tggggaaggg
    11581 agtaatgacg atatccccta ttctgaaaga ctgccccttt tcaaaatagg cccagggagc
    11641 ctccggcgct ttttcctgga cgcacatggc cgtatggcgg gtggcgtaaa cacgcacggc
    11701 atgctttctg gtgaactggt gcacgccttt catgtggtcc gcgtgttcgt gggtaagcag
    11761 aatggcgtcc agctcatccg gctccactcc ggcggacttc atcttatccc gcagcctggc
    11821 ggcgctgaac ccggcatcca ccagcaggac ggtttccccc gccctgacaa tggtggcatt
    11881 tcccccgctg ccgctgccca acacgcaaaa ctgcatcatg cgcggaatat aataccgccc
    11941 ccggaaggga gcaagaccgt atccatgctt ttttttatga catgggaaca tgaaaaaata
    12001 cttttttcca gtacggggtt gacatttcag gtgcattaaa gtgtattgaa gtcactacgt
    12061 agtgtacttg catgcgatga gcagtgtatc agacaacctt tttggtgcat acacgcacaa
    12121 gctggacccc aaaaaccgga ttgccattcc ggccgaatgg aggccctccg aaggttgcgc
    12181 cctgctcctg ttatccggcc ggcgccttga tttgccgacc gtcaaagcct atacgcggga
    12241 aaaattccag caactcattg acaagataga aacaacgccc ggctatacgg aagcgcaaat
    12301 cgacctgttc atcggtaaat tatacgccaa ctgtgtggag gctgtcatca acgcccaagg
    12361 caagctgctg atacccaaac aaatgtgcga acacgcacag ctcagttcct ccgtccggct
    12421 cgccgcgcgg agaggatatt tcgaattgtg ggagccctct ctctatgaag aagtttcccg
    12481 gcgtgaaaac gccagcatct ccgacatcaa ccaatcctac ggcattctct agctttcctt
    12541 catgccccca gactcttcca ttctgcccaa tccccaggca cgcccctgcg caacgcttgc
    12601 attgcgcccg ggctggcttg cttccggcct gggcgtcggc gccagaaccg ggctgcatgc
    12661 ggaactcacg gcttattcca tcgttttctg ggggcacgac gcccttccgg cgcaggatat
    12721 ggttgcctgg caacaggaaa aagcacgcct tatggaggaa atgtccctgg ccgggcaaaa
    12781 gagcgcctat ggcaagctgg gcgcattgtc ctccgacctg aaccgggctt ttgacgacca
    12841 tattgagctt tctttacgcg cgggcgcggg tacgcacatc cgcacggagg aagtgcaggc
    12901 cctggcaaac ggacttgcgg aagaaacgtc ctgccgcgta ctggcgtgga gcgtctgccg
    12961 caaccatgtg catgtggttg cggagctgac ggaggagaag ggagtggatg aactggtctg
    13021 ctcctggaag gcgctggccc cctccatgaa ctgggagaac gcgtaccaca cggaagccct
    13081 gaaagcccgg gaagccgcgg caagggcgga tgccctgatt tccgaacttg gggatgacgc
    13141 ctttgccgct gttgatgcgg aagcggacgg aaccgtctcc ggaaacggtt tccggcacat
    13201 taccgttctg ctgcatgaaa cggtggacat gctgaaagcg ggccccggca aattcatcgt
    13261 ggactgcacg cttggcggcg ggggccacac ggagcttctg ctggaacagg gcgccaccgt
    13321 ctggggcatt gaccgcgatg cggacgcccg ccgcgccgcc atgctcaggc tggcgcgctt
    13381 cggttcccgt ttcaaggcgc tcgccggcaa cttccaggat gtggaaagca ttctttccca
    13441 gcagggggtt tcccgggtgg acgggctgct ggcggatctg ggcgtttcct cccaccagct
    13501 tgacaccgcc tcccgcggtt tttcttttcg ggaagacggc cctctggaca tgcggatgga
    13561 tacccgcgcc gccttttccg cccggaacct ggtgaatgag gccccggaag aagaaatcgc
    13621 agccattctc tggcaattcg gagaggaacg cgcttcccgc gccattgccc gcgccattgg
    13681 gaaagcccgc gcccaggccc ccatcaccac taccgcacag cttgcccgca tcgtggaatc
    13741 cgtcctgccg cgcaaaggaa ggcagcaccc cggcacccgc acgttccagg ccctga
//
