LOCUS       c00117_gnlPro..        11228 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCOHNDGE_117.
ACCESSION   c00117_gnlPro..
VERSION     c00117_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:00:24
            Original ID  :: gnl|Prokka|LCOHNDGE_117
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11228
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11228
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7286:11227]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7287..11227
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..11228
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11228
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..86)
                     /locus_tag="ctg117_1"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGK"
     CDS             complement(122..2584)
                     /locus_tag="ctg117_2"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCEEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPAEAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGKQATLQRPSVDGFKVENHDLDIEVVVEN
                     SEACPHYAGVTVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTLPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVCVAAPQDFMVELSYEKVNSLIGKVIPVETIKSIVTSLEMKIMNETVDGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLVAEQL
                     VGCGFNEILNNSLTRAAYYDGLENYPSNHLVMLLNPLSADLNCMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFDADKKNPEKVLATYSEDYHLGLWVTGKKVANSWAHPDENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDIFATALSVHTKGGKRLASFGVVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNVQFAEIEKIA
                     YDTEKKLLKEVELFDVYEGKNIEAGKKSYAVSFLLQDETQTLNDKMIDKIMSKLVKNLE
                     DKLNAKLR"
     CDS             complement(3185..4738)
                     /locus_tag="ctg117_3"
                     /transl_table=11
                     /translation="MAEQRRNSRNTKSTKVQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYEHRHQLIYAAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNPVALFSLEMSNVQLVNRLITNVCEIPSEKIKS
                     GQLASYEWQQLDYKLKDLLDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPAGAMLGSKLNAGAMPPPPPEPDFVPQGNNPFGATEGPLPF
                     "
     CDS             4937..5761
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_4"
                     /sec_met_domain="GHMP_kinases_C (E-value: 6.2e-10,
                     bitscore: 28.9, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.2e-10,
                     bitscore: 31.0, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITFPNAKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSP
                     EADKKFSLHQYGMEISGNPEDNLVVKAYLLLDKEFHLSPIEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNEHFQLNLSEDQLEIYAATLGADCAFFIRNAPTFAEGIGNIFSPIPLSLK
                     GYQILIIKPDVFVSTREAFANIHPHHPEYSIKEAIKRPANEWKEILINDFEDSVFPQHP
                     VIGEIKAELYRQEAVYASMSGSGSSVYGLFEPEGTLPETDWGTNVFRFKGRL"
     CDS             complement(5994..7028)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_5"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 6.9e-53, bitscore:
                     169.5, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVEKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTIASGAPINAILLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEQKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANQELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(7287..7859)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.9e-63, bitscore:
                     203.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDAFGLGYLQTITFILVIAGLVQMVEIILKKVSPSLYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFGLALVLFAGLREQMTLVKIP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             complement(7882..8448)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 9e-71, bitscore: 226.9,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPIFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISSIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPDLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPLASMFDGIGMGFGFTIALTLLGAVREFLGTGKIFNLTILPEEYGML
                     IFVLAPGAFIALGYLIAIINSLKKA"
     CDS             complement(8484..9167)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_8"
                     /sec_met_domain="FMN_bind (E-value: 6.9e-24, bitscore:
                     73.8, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     YTNNPVAESDTVFSEKDGKKIVDFIIYPAKNGEKWVGSAVEAKSMGFGGELKVLVGFDA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPAKNEKPVSHEESAKSILGMNPGETPLAV
                     TKDMNGQVDAITASTITSRAFLNAVNAAYQAYKGGEVDTNSGASQKNEPAVAPEGEAAA
                     NDTNN"
     CDS             complement(9194..10186)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_9"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.7e-121,
                     bitscore: 393.0, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIVKFLMKKPATTICDGSAVITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPVVGQLTSYMDATTGATPL
                     ALMKQAIHGDASALSQIPDALTLFIGQNGGCIGEVSALALLLGLVYMLWKKIITWHIPV
                     SIIVTVFVFAGIMHMVDPEKYVSPVLQLLSGGLMLGAVFMATDYVTSPMSKKGMLIYGV
                     CIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             complement(10199..11227)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_10"
                     /sec_met_domain="Fer4_10 (E-value: 5.8e-09, bitscore: 25.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.8e-17, bitscore: 51.1,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.2e-51, bitscore:
                     164.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-06, bitscore: 18.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IDTVVDASGYAKPAIFIDVEGDEWEETIDRSKTLVKECELSSEEI
                     VKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIINAVECEPYLTADHQLMLEHAEEV
                     MVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASSYAGIEVVPLKVKYPQGGEKQLI
                     DAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKNKPLFERVITVTGKSVTKPSNFL
                     ARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVNIEVPTAKGSSGILIMNQKEAKR
                     GEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETMEKERIMDCIECGSXXXXXXXXX
                     XX"
ORIGIN
        1 tgtttaccca gtcttgtaaa tgttttggcc atgtggcccc atcttttcag ctttgcggct
       61 tttctatatt caaatgctct tcccattggt ttgtattaat tttgaattgt gaattttaaa
      121 tttatctcaa ttttgcattc agcttatctt ccagattctt caccagttta gacatgatct
      181 tatcgatcat cttatcgttc agcgtctgag tttcatcctg aagcaggaag ctgaccgcat
      241 acgatttctt acctgcttcg atgttcttac cttcgtatac atcgaagagt tccacttctt
      301 tcagcagttt cttttctgta tcgtaagcga ttttttcgat ttcggcaaac tgtacgttct
      361 tgtcgagcaa caatgccaag tcacgcttca cagcagggaa tttggaaatt tccttgtagc
      421 tgatcttcac tgaacggata gccttcatca gttctttcca gttcaagtcg gcataataca
      481 cctcattatc tatatcgaat gctttcagca gtttcttcgt cacaacgccg aaagaggcaa
      541 gacgcttccc ccccttggta tgaacagaaa gtgcggtagc gaaaatatcg tcagtcagat
      601 tgccaactac caagttgtgc aaatccagtc ccaggcgctt caatatattc tctacataag
      661 ccttcaattc gtataccgaa ctgttttcat ccgggtgtgc ccatgaatta gcgactttct
      721 ttccagtcac ccacaaaccc aagtgatagt cttccgaata ggtagccagt actttttccg
      781 gattcttctt gtccgcatcg aagtaatagc aattaccgaa ttcgaagaat ttcaaatcgg
      841 cattcttgcg gtttgcattg tgagcgatgc tttccagtcc accgaacagc aatgtctgac
      901 gcatacagtt cagatcggca ctcagtggat tcagcagcat caccagatgg ttggatggat
      961 agttctccag accgtcgtag taagcggcac gagtcagaga attattcagt atttcattga
     1021 agccacagcc aaccaactgt tctgcaacca gattctgtaa tttgtttgat ttatcatgct
     1081 cacccttggt tgtcagactg gagttcagcg tagtcgggat ttctacatta ttatatccgt
     1141 agatacgtag aatatcttcg atcacatcgc aatcacgctg tacgtctaca cgataaggag
     1201 gaacggctaa tgtcagtccg tcaactgtct cattcatgat tttcatttcc aggctggtaa
     1261 caatgctctt gatcgtttcc acgggaatca ctttaccaat cagcgaattt actttctcat
     1321 aagaaagttc taccataaag tcttgtggag ctgcaacgca aacatcctta atttcggatg
     1381 agatagtgcc accggccagt tctttcacca tcagagcagc cagtttcaga caatagatta
     1441 ctccgttcgg atcgatgcca cgttcgaaac ggaaagaagc atccgtattc agaccgtgac
     1501 gacgggcagt cttacgcacc catgtaggat ggaaataagc gctttcgata aatacatctg
     1561 tcgtagcttc cgtagaaccg gaatccagtc cgccgaatac accggcaata cacatcgctt
     1621 cttctttgtt gcagatcatc agatcgcgtt cgttcaactt gcgttccact tcatccaatg
     1681 tgacgaatgg agtgccttcc ggcaatgtct tgacaattac ttcattgcct tttatctttc
     1741 cggcatcgaa acaatgcaat ggctgaccga aagcatgaac gatataatta gtaatatcca
     1801 ctacattatt aataggacgt acaccgatca agcgcaattt attctgcaac cattcggggc
     1861 tttccttcac agtaacgcct ttcaccgtaa cgccggcata gtgaggacag gcttcgctgt
     1921 tttcaaccac tacttcgata tccaaatcat gattttccac cttaaatcca tctacagatg
     1981 gacgttgcaa agtagcctgc ttgccattct gaatcaggta agcatacaag tcgcgggcca
     2041 caccatagtg tgagcaagcg tctgcacggt taggagtaat atctacttcg agtacgtagt
     2101 cactcttgat attataatag tctttggcga gagtacccgg aacagcttca gccggcaaca
     2161 cgatgattcc tgcatgatca gtaccaatac cgatttcgtc ttctgcacaa atcatccctg
     2221 tagattctac accacggatt tttgacttct tgatagtaaa gcattcatca ccgtcataaa
     2281 gtttggtacc caaagtggca accactactt tctgtccggc agctacattc ggagcaccgc
     2341 atacaatctg tacaggttcg ccgtctccca gattgacggt agtgatatgc aaatggtcgg
     2401 aattcggatg ttcttcgcaa gtcagcactt caccgattac gagtccttcc aaaccaccct
     2461 taatggtttg cacttcttct acaccacctg tttccaagcc gattgaggtc agcgcagcag
     2521 ccgtttcatc gggggtcaaa tcaaagttga catactcttt cagccagtta taagagatat
     2581 tcatataatt aaatttttat tgtttctcaa aaagtttcgc aaagttaata agatttttcg
     2641 gttgaccgaa aaggttctta aaaaagttga gagttatttc accacagagg acgcagagtt
     2701 ctaattcaga gataattata acctctgcgc cctctgtgtc ccctgtggtg aaaagaatca
     2761 aaaaaggtgt gtttcaataa gggcatccgc ccccttaata aacgccaaat aatgtaaaag
     2821 ccggaaactt tcaaaactat ctgctgttgt tgtgggaaat tcgacgggga aacaccccat
     2881 cgcnnnnnnn nnnttcgcaa agttaataag atttttcggt tgacatagaa cgatttgaga
     2941 gaaaaatgtc aagagaagct aaactaacaa ggacctgact gtattattcc ccaataaatt
     3001 catggttggt gacaaagtgg caaaaaaata aaggggtatt ctttgtcatt tttgccacct
     3061 atccctatca gaatacaacc tggctatact ctataaaaaa taatcgaccg ctcgattgga
     3121 gtaaatcgag cggttatttt catctgacta agcggtcatt ctattcaacc caaaagacgt
     3181 ttttttagaa aggtaacggt ccttccgttg caccgaacgg attatttccc tgcggaacaa
     3241 agtccggttc cggcggaggc ggaggcatag caccggcatt cagtttagac cccagcatgg
     3301 cacctgcagg ttcacccggc atcggtataa ccatatcatc ttccggatta gagaatcgtg
     3361 taaactcacc tttgaatcgg agcaagactt cacctaccgc accattacga tgcttggcta
     3421 tcacaatttc cgccataccg cgaaggtcgt taccacgatc atcctgataa atcttataat
     3481 attccggacg gtgaataaaa cacaccatat cggcatcctg ctcgatggct ccggattcac
     3541 gaaggtcact caactgaggg cgtttaccgt caataccttc acgactctcc acaccacgat
     3601 tcaactgcga caaggctata atgggaatgt tcaactcctt tgccaatcct ttcaacgaac
     3661 gggatatcgt actaacctct tcctgacggc taccgaatgc cataccactc gcattcatca
     3721 actgaaggta gtcaataata atgattctca ccccatgttc acgcaccaga cgacgtgctt
     3781 tggtccggag ttcaaacaca gacaaagacg gagtatcgtc cacataaagc ggagcatcca
     3841 gcaggtcttt cagtttgtag tccaactgtt gccactcata gcttgccaat tgtccacttt
     3901 tgatcttctc actcggaatc tcacaaacat tggtgataag acggttgacc aactggacgt
     3961 tactcatttc aagagagaac aacgctaccg gattccgata atcaacagca atattcttag
     4021 ccatagaaag tacgaaagct gtcttaccca tggcaggacg ggcagcgatt ataataaggt
     4081 cggagttctg ccaaccggag gtcatcttgt ccagtttcgt aaatccactt tcaagaccac
     4141 tcagaccgtc cgttcgtgca gccgctttct gaatcagctt atacgcttcg tcaattaccg
     4201 gattaatctg cgtatagtct ttcttcatat tctgctggga aatctcaaac agcttgcctt
     4261 ccgcctcctg catcaagtcg tccacatcca gtgtctcatc aaaagccttg ctttgaatat
     4321 tactggtaaa cgttatcaat tcgcgcgcca acgatttttg tgcaataata cgggcgtgat
     4381 attcgatatg tgcggaagaa gcaaccttac tgctcaactg agtaatatag aacggtccac
     4441 cgacctcttc caactcacct cttttgctca actgctcttt gaccgtcaga atgtccaccg
     4501 gcttctgatt aacggcaaga tcagtaatgg cagcataaat caactgatga cgatgctcat
     4561 aaaatgactc cgggcgaaga atctcactca ccagcgaata agcatccttc tcaatcatta
     4621 aagcacccaa caccgcctct tccagctccg gtgcctgagg ttggatacga ccataatcat
     4681 tgaccggttg tactttagtt gattttgtgt tacgggaatt tcttctttgt tcagccatct
     4741 gcttatatac aattttatga tttacaattt atgatccccg gcttttatac atagtaaaat
     4801 ccgaaaggga tgacaaagat agaatataat aatgaagaaa agataaggaa aaatgaagat
     4861 tttagtaact ttgtcaccaa tagcataaat tcgcaaccca taatttaaaa ttcaaaaata
     4921 ataattcaga acgaatatga tcactttccc aaacgcaaaa ataaacctgg gactctctat
     4981 taccgagaag cgtccggacg gatatcacaa cctcgaaacc gtattctacc ccgtcgctct
     5041 cgaagatgcg ctggaaatcc ggaccagccc cgaagcggac aaaaagttct ccctgcatca
     5101 gtacggaatg gagatatccg gtaatccaga agacaattta gtggtgaaag catatctgct
     5161 attagataaa gagtttcacc tctctcctat cgagatccat ctgtacaaac acattccttc
     5221 cggtgccgga ctgggaggag gctcatcaga cgcagctttc atgctgaaat tactcaacga
     5281 acactttcag ctgaatttat ccgaagatca gctggaaata tatgccgcaa ctttgggagc
     5341 agactgcgct ttctttatca gaaacgcccc gacctttgcc gaaggaatcg gcaacatatt
     5401 ctcccccatt ccactatcct taaaaggata tcagattctg atcatcaaac cggatgtatt
     5461 cgtatcaacg cgggaagctt tcgccaatat tcaccctcat catcccgaat actcgatcaa
     5521 agaagcgatc aaacgcccgg caaatgaatg gaaagagata ttaatcaatg attttgaaga
     5581 cagcgtattc ccccagcatc cggtgatcgg agaaattaaa gccgaactat acaggcaaga
     5641 ggctgtttat gcctctatga gcggttccgg ttcttccgta tatggattgt tcgagccgga
     5701 aggaacttta cctgaaaccg attggggaac taacgtattc cgttttaaag gcaggctgta
     5761 aaggagtaac aaaaaacggt accacgactc ccgtcgtagt accgtcacaa cacaaacaca
     5821 aaataaaaca cgacaaaact actatgcaat catacctgtc tatgccggag aggcataagt
     5881 accatttact catattcaca tactcacaaa cagatcaagc tgattagcat ctaataaaca
     5941 aatcgcatga acgatttgtt taaactttta tgttaattaa aacaaatatc tttttactga
     6001 atgcctcttt cacggagttt cagctgccaa ttccatgcag agcgtaaagt atcttctaat
     6061 gtttctaccg ctttccaacc cagttcctgg ttggcaaaat cggggttagc ccataccttt
     6121 tcaatatcac ctgcgcgacg gcctacaatc tgataattca gtttaacgcc agtagctttt
     6181 tcaaagccat taatcagttc caatactgaa acaccgcgtc ctgtaccgat attgaatact
     6241 tctacttttt ctttctgttt ttgctccaaa atacggcgga ttgcaatcac gtgtgcttta
     6301 gccaagtcaa caacgttgat aaagtcacgg atacaagaac cgtcaggagt atcataatcg
     6361 tcaccgaata cacttagttt ttcacggata cccatcgctg tctgagtcag ataaggaatc
     6421 aggttttgag gaacaccgtt cggaagttca cccagcaatg ctgtaggatg tgcgccaatc
     6481 ggattgaaat aacgcagcaa aatagcattg atcggggcac cggaagctat tgtatcacgg
     6541 ataatttctt cattaatctg ttttgtattt ccataaggag attccgcttt cttgatcgga
     6601 gccttttccg ttacaggcaa ctcatccggt tgaccatata ctgtacagga agaagagaac
     6661 actatgcctt ctactccatg tttaggcatt aactccagaa ggttgattaa agaaaccagg
     6721 ttgttacgat aataaagcaa cggcttctct accgactctc ctactgcttt gcttgctgcg
     6781 aaatgaataa tcgctttaat tcctttatat ttggcaaata cggcatcaag gccagcaaaa
     6841 tcaagacaat ccagtttctc aaaagctggg cggataccgg atactttctc tatattgtca
     6901 acaacgtcag cactcgaatt tgataaatta tcgataatga ttacttcgta tccactgttt
     6961 tgtagttcta caacggtatg agacccaata tagcctgttc ctcccgttac taaaattctt
     7021 tctttcatat aattttaaaa tatggttagt ttttcggttt tcagtttgtt tgaggtacaa
     7081 atgtatggaa ataaaatgga aatgcaataa actatcgcaa ttttattcac aggaagatac
     7141 ttacgggacg atttgagggc gttttggtat gataaaaaac atattcggta tgaacagata
     7201 taaagaaaaa ggccggaaac aaactgcctg tatgttgcca tacgacagag tttccagcct
     7261 ctttatctaa ttatcaactt agtcttttac acgacgccag agaagcccat gaatgccatt
     7321 gccagcaaac ctgcggtaat caaagcaatc ggagtcccct gcattccttt cggaatcttc
     7381 accagggtca tctgctcacg caatccggca aacaatacca gtgccagacc aaagccaaga
     7441 gcagtagaga atgcatatac aacacctgtc agcagatcaa agtctttctg gattaccagg
     7501 attgccacac cgagaataca gcagttcgtt gtaatcaacg gcaggaacac ccccagtgcc
     7561 tgatacaaag aaggagaaac tttcttcaga ataatttcta ccatctgcac cagtccggca
     7621 ataaccagaa taaaagtgat tgtctgtaag taccccaatc cgaaagcgtc caacacaaac
     7681 ttctgaatca ggaatgtgac gatggtagcg atagtcagca cgaaagcaac tgccgcactc
     7741 atacccatcg ctgtttccac cttcttggaa acacccagga acggacagat tcccaggaac
     7801 tgcgacaaca caatgttgtt tacaaagatt gccgagataa atatcaatat atattccata
     7861 ttcttttctt atttaataga gttaggcttt cttcagacta ttaataatgg caatcagata
     7921 acctaaagcg ataaaggcac ccggagccaa aacaaagatc agcattccgt attcttccgg
     7981 cagaatggtc agattaaata tcttacctgt tccgaggaat tcacgtacgg cacccaacag
     8041 agtcagggca atggtaaaac caaatcccat accgatacca tcaaacatag aagccagcgg
     8101 attgttcttc gctgcaaaag cttccgcacg tcccaatacg atacaattta ctacgatcag
     8161 cggaatgaaa agaccgaggg tagcatacag atcgggcacg tatgcttgca ttatcatctg
     8221 caacagtgtc acgaatgacg cgatcaccac gataaatgaa gggatgcgta ccatatccgg
     8281 aatcagattc ttgatagatg aaattaccac gttcgagcaa atcaggacga acatagtggc
     8341 cagtcccata cccataccgt tgattgccga tgatgtcgta cccagtgtag gacacatacc
     8401 gagcaggagc acaaaaatag gattctcttt gataatcccg ttcatcatta ctttaaaatt
     8461 attcataact gtctcctcct ttcttagtta ttagtgtcat tagcagctgc ttcaccttcc
     8521 ggcgcaacag ccggttcatt tttctgggaa gctccggaat tcgtatccac ctcaccgcct
     8581 ttatatgcct gataagcagc attcaccgca ttcaggaaag cacgtgaagt gatagtagaa
     8641 gccgtgatag catctacctg tccattcatg tctttggtca cagccaatgg agtctctccc
     8701 ggattcatgc ccaaaataga ctttgcactt tcttcgtgag ataccggttt ttcgttcttt
     8761 gcaggatcat aagctccaaa ccatttgtcc gctttcgaac ccaatcccgg agtttcagcg
     8821 tgcgccaata aagagtagtt ataaatcttg ccttcagcat caaagcccac cagcactttc
     8881 agttcaccgc caaatcccat tgacttggct tcaacggcag aacctaccca cttttcgcca
     8941 ttcttggccg gatagataat gaaatccacg attttctttc cgtctttctc gctgaaaaca
     9001 gtatcgcttt cggctaccgg attattggta tattcaggaa gcaccttttt caaggcctcg
     9061 ttcagcgtct ttgcattcgc ttcggcaata gggcctttcg tcagttcgtt cacataagcc
     9121 agcaacgcta cggaaacagc tgtaacgccc gtaagtacca gcaacatatt ctttaaagat
     9181 gattgtaact ttttcatttc ttcttcgcta cctccccaaa gcgtttaggt ttacaatagg
     9241 tgttaatcag cggagtgaac gcattcataa tcaggatggc gaatgacata ccttcgggat
     9301 atgcaccgaa cagacggata accaccgtca gcagaccgat acaaacaccg taaatcagca
     9361 tacctttctt gctcatcgga gaagtcacat agtcggttgc cataaagaca gctcccagca
     9421 tcagacctcc ggagagtagt tgcaataccg gagaaacata cttttcggga tccaccatat
     9481 gcataatgcc tgcaaataca aatacagtca caatgataga aaccggaata tgccaggtga
     9541 tgatcttttt ccagagcatg tataccagtc cgagcaacag tgccagcgca cttacttcac
     9601 cgatacatcc gccgttctgt ccgataaaca gagtcagcgc atcaggtatc tggctcaaag
     9661 cacttgcatc gccgtgaata gcctgtttca tcaatgccag cggagtagca ccggtggtag
     9721 cgtccatata agatgtcagc tgacctacta ccggccatgt tgtcatctgc accgggaaag
     9781 aaagcaacag gaatacacgt cccgccaatg ccgggttgaa tgggttgcag cccagaccac
     9841 cgaaagacat cttgcctaca ccgattgcga acagtgcacc cagaatgata atccagatag
     9901 gcagattgga aggtagattg aatgccagca acacacctgt aatgacagca gaaccgtcac
     9961 aaatggttgt agcaggtttc ttcattaaga atttaacgat cgcccattcg aagaataaac
    10021 aggctgctac cgaagtagcc gtgacaatca gagcccccag cccgaagaaa taaagagaca
    10081 ccagaaaagc cggaatcagt gcgatcagca cgccatacat atttttctgt acgctgtctc
    10141 cgccatgaac gtggggtgat agtgatacga ttaatttatt ttccatattc gttatttttt
    10201 agcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnngaacc gcactcgata caatccatga
    10261 ttctttcttt ttccattgtt tcaaaatctc cgttttcgga caaagctccg agcaagtacg
    10321 gctccagtcc catcggacaa gcgctcacac actttgcaca acggatacag gtttgtgctt
    10381 caccacgctt ggcttccttc tgattcatga tcaggatgcc ggagctgcct tttgcggtag
    10441 gaacttcgat attcaccaaa gccttaccca tcatcggacc accgccaatc acctttcccg
    10501 tatcctccgg cagaccgccg caagcatcaa tcagctgttt catcggtgta ccgatacgcg
    10561 ccaggaagtt ggaaggtttg gtcacagact taccagttac ggtaatcaca cgctcaaaca
    10621 acggtttatt tttctgaaca gcttcataaa cagcaaatgc cgtacccaca ttctgcacaa
    10681 ctgccccagt agagataggc agcgcaccac ttgccacctg gcgtttggta atcgcatcaa
    10741 tcaactgttt ctcaccgccc tgcggatatt tcactttcaa aggaacaact tcgatgcctg
    10801 cataactaga agcaactttc gtcatcagtt caatagcatc cggcttgtta ttctcaattc
    10861 cgataaatgc cttatttacc ttcacggctt tcatcagaat ggagacacct accatgactt
    10921 cttccgcgtg ttccagcatc agctgatggt cggcagtcag atacggttca cattccaccg
    10981 cattgataat cacacattct gccttgaacg aaggcggcgg acaaagtttc acctgtgtag
    11041 ggaaacaagc accacccaaa cctacgatac cggcatcggc aatcttcttc acgatttctt
    11101 cggacgaaag ctcacattct ttgaccagtg tcttgctacg gtcaatggtt tcttcccatt
    11161 cgtcgccttc tacatcaata aagatagcag gttttgcata accgctcgca tcgactactg
    11221 tatcaatc
//
