LOCUS       c00001_gnlPro..        15457 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NDHLHBNA_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:44:07
            Original ID  :: gnl|Prokka|NDHLHBNA_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15457
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15457
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2486:5457]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2487..5457
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15457
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15457
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(3..608)
                     /locus_tag="ctg1_1"
                     /transl_table=11
                     /translation="MKQYVYLLILPIMFLISCSDDTVEEMGGSNHVLLERYPQEVINIS
                     MDNPESFASFNKTSVTRSSELLKDSVWSSGNGHTLIYETNEHIPTQGLMRYIYLGSILQ
                     GGSIEKQRFVPIVKPMDPITISYSFPARWVTDIIAKPSLSAQRQSLQNIMNKEGMTGKQ
                     LGSFTYNMRQFSYFEELKLAFGANVNIGGLLNIDVSLDK"
     CDS             complement(641..1480)
                     /locus_tag="ctg1_2"
                     /transl_table=11
                     /translation="MKKIFILLFVSLALFSCEKEENNKIFKYQLLPSENVSKPFSCLGE
                     KRTITFTIIQKTLIDDILDSEVPIIPKDVSIEFDKTLFSDIETKIKGDQVVLNITSNIN
                     KEDKILNVDLQISYSTINGIKVEKIPLIIDKGKLTFVYKIHSEQNPFVLPAEGGKFELP
                     FICKKQTYLNDQFIEETYSSLNGLRFKTISTGNVWFLTVRKDGEKIGFYKFTFVGEGPY
                     NQKTDPECYFNIYTHDANLITDNPTEIFRQDFIQPQTPGEDYYKPSRSSYKHGTFDF"
     CDS             2487..4715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_3"
                     /sec_met_domain="Gly_radical (E-value: 1.9e-45, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             4729..5457
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4"
                     /sec_met_domain="Radical_SAM (E-value: 5.5e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(5450..5899)
                     /locus_tag="ctg1_5"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDKDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(5886..6053)
                     /locus_tag="ctg1_6"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(6113..6616)
                     /locus_tag="ctg1_7"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             6810..7040
                     /locus_tag="ctg1_8"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             7127..9241
                     /locus_tag="ctg1_9"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYACTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(9311..9616)
                     /locus_tag="ctg1_10"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     DARKKAKITQAELARRIGSDRSYISRVESGQTEPKVSTFYRIMNALGCKIEFSMIL"
     CDS             complement(9597..9929)
                     /locus_tag="ctg1_11"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
     CDS             9946..10227
                     /locus_tag="ctg1_12"
                     /transl_table=11
                     /translation="MLFNYTTHFLVLYYFSSSSPPKVRGVREELKLFLFYFFISTFYIS
                     LKKNTNVRNPLSLLSLFTFSFSKKTAENRKNTTVFFQFPTAFSNQPTN"
     CDS             complement(10479..10790)
                     /locus_tag="ctg1_13"
                     /transl_table=11
                     /translation="MSTKNNMLTDISAELDKEFGAPGTPEREKFDEEAYAFYTGQILLD
                     ARREAKVTQSELAKRINATKSYISRIESGAINPSVGTFYRIINALGLKIEIVKPIMGI"
     CDS             complement(10762..11103)
                     /locus_tag="ctg1_14"
                     /transl_table=11
                     /translation="MRRKVIAYGQYYKDFLATLTEKEIQKVKYVLSLLGTEDRLPIKFI
                     KVIRDGLYELRISYNGNIYRIFFIFDEGQIVVLFNGFHKKTQKTPSSEIDKALKIKEEY
                     YEYKKQHAD"
     CDS             complement(11196..11450)
                     /locus_tag="ctg1_15"
                     /transl_table=11
                     /translation="MTPTVIEYRGDPKRYVSVILGAIDRGRLTYNGDANCEQTFRSLSS
                     VIDVISPKNGKALSIETLVSYEKKERAGEFSDYSEGKFE"
     CDS             complement(11468..11602)
                     /locus_tag="ctg1_16"
                     /transl_table=11
                     /translation="MENSLSDELFCSLKNELREVDAQISVHSKKLLELIDQKKELSSN"
     CDS             complement(11720..13078)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 151; E-value: 1.4e-46)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_17"
                     /sec_met_domain="MFS_1 (E-value: 6.6e-46, bitscore: 151.0,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKLLDFYKISPPVSGGETDPERSVRFKRIRWATFLSATTGYGI
                     YYVCRLSMNVIRKPIVEDGVFTETQLGIIGSCLFFVYAVGKLTNGFLADRSNVKRFMST
                     GLLCSALINLCLGFTNSFFAFVLLWGLNGWFQSMGAASGVVSLTRWYSSKERGTFYGFW
                     SASHNLGEALTFISIALLVSWMGWRYGMIGAGVIGLLGFLMMLAFMRDTPQSQGFLLDR
                     WGTSDAHSVSGKQTEEFNKAQKAVLKNPAIWILALSSAFMYISRYAVNSWGVFYLEAQK
                     GYSTLDASFIISISSVCGIVGTVFSGIISDKFFAGSRNVPALIFGLMNVSALCLFLLVP
                     GVHFGVDALAMVLFGLGIGVLICFLGGLMAVDIAPSNASGAALGVVGIASYIGAGLQDV
                     MSGILIEGQKTVQNGVEVYDFTYINCFWIGAALLSVVFALLVWNAGEKRSEIN"
     CDS             complement(13094..14014)
                     /locus_tag="ctg1_18"
                     /transl_table=11
                     /translation="MKKYIMIGILFAFPFCLSADEPVKAIYAKITNPDNKEITVVAHRA
                     DWRYAPENSLAAIESSIRLGADVVELDVQKTKDGQLILMHDKTLDRTTTGKGKVAEWTL
                     DSIRTLYLKNGAALKTKHRVPTLEEALWVAKGRVMVNLDKAYPIFDEIFPILEKTGTVD
                     QIIMKGSKPVADVKKDLGKYLDRIIYMPIIHLDKPGAMKQLDDFMTELHPVAFELLFVS
                     DTCQAPKQVKTKLKGKSKIWYNTLWDTMAGGHDDDKSLENPDEGYGYLIDTLGAAIIQT
                     DRTAYLLEYLQSRKKRSENGQDAYH"
ORIGIN
        1 cccttatcaa gactgacatc aatattaagg agcccgccta tgttgacatt tgctccaaaa
       61 gcaagtttta actcttcaaa ataggaaaat tgcctcatat tataagtaaa agaccccaac
      121 tgtttacctg tcatgccttc tttattcatt atattctgca aagattgcct ttgtgctgaa
      181 aggctcggtt ttgcgataat atcagtaacc caacgagctg gaaaagaata tgatattgta
      241 attggatcca taggttttac aataggaaca aagcgctgct tttcaataga tccaccttga
      301 agaattgaac ctaaataaat atacctcatt aacccttgag ttggtatatg ttcatttgtt
      361 tcataaatta atgtatgtcc atttccacta ctccatacac tatctttcaa taattcagaa
      421 gaacgagtaa cggaggtttt attaaatgaa gcaaagcttt ctggattatc cattgaaata
      481 tttatcactt cttgagggta tctctcaaga agaacatgat tagagccacc catttcttca
      541 actgtatcat cggaacatga aattaaaaac ataattggca aaatcaacaa atatacatac
      601 tgtttcataa ttaatataat taaggttaat actgaatatg ttaaaaatca aaagtaccat
      661 gtttataaga ggatcgagaa ggtttataat aatcctcacc cggggtctgg ggttgtatga
      721 aatcctgtct gaatatttcc gtaggattat ctgtaatcaa atttgcatca tgggtatata
      781 tgttaaaata acactctgga tctgtttttt ggttatatgg tccttctccc acaaaagtga
      841 atttgtaaaa acctattttt tctccgtctt ttctgaccgt aagaaaccag acattaccag
      901 tacttatcgt tttaaatctc aatccattta atgatgaata agtttcctct ataaactgat
      961 cattcaaata tgtttgtttt ttacaaataa agggcaattc aaatttccca ccttcagctg
     1021 gtagaacaaa aggattctgt tccgaatgga ttttatacac aaatgtcaac ttccctttat
     1081 ctataattag gggaattttt tctactttta taccattaat agtagagtaa gaaatctgta
     1141 gatcaacatt caaaatttta tcttccttat taatatttga ggttatattt aatacaactt
     1201 gatcaccctt tatttttgtc tctatatcag aaaaaagagt tttatcaaat tctatcgaaa
     1261 catccttggg aataatcgga acctctgaat ctaaaatatc atctatcaat gttttttgaa
     1321 taattgtaaa agtaatagta cgtttctccc ccaaacaact aaatggttta gatacgttct
     1381 cacttggcag caactgatat ttaaaaattt tattattttc ttctttttca caggaaaata
     1441 atgctaagga aacgaacaga agaatgaata tttttttcat attaatacaa tttagttttt
     1501 tgcaaattaa aggatttttc ctgtacaata aaataccaat taattggtat tttattacaa
     1561 ataaccattc aatttcatta ttatgcccaa agcatgaaaa taaaagtata acatacaaga
     1621 gctgtaaaca aatccacgat caacacaata aaataaatcg tttatgcatc tttgcgatat
     1681 gcatttatgc aaaatcatac aaatttcttt atcagtaaaa tacccattaa ttagtatttc
     1741 attgacaaaa tgaaatgtac tttaaaagcc caaagttata ttcaattcat aacctaaatg
     1801 cctatccaat ataaaaataa tgcgtttagc accaagatac aaacagaaca acacaaaatc
     1861 aagctctaaa ggaatgtatt actattataa aagacagaat tattcgggag attccctact
     1921 ctaaaaaagt taaagaaaga aaatgattca aataaatatt agtataacaa tatcaccaac
     1981 aacacaatat ccccttttca aattatacaa taaataatag ttaaagcaac taaagacagt
     2041 gcaaagccaa ataagtaata aaagagcaaa gtattaaata aagcaaaaac acccaatttt
     2101 actttttagg gtgtaaaatt gggtgccatt cttgtaaatc actgattatc agcatttatt
     2161 gcggagagac agggattcga accccgggta cctcgcggta caacggtttt caagaccgcc
     2221 gcaatcgacc actctgccac ctctccaaaa cttccttatc agaagtgctt ttcgttaaaa
     2281 gcggtgcaaa ggtacgaaga tattttaaac ttgcaagagt tttcactaaa aatttaatct
     2341 aatcttttcc taaggatagc aattaatagg tattttatgt tgaaaagcat aaaatagagc
     2401 atatttatgc tgattatatg aaaaatgatt gtaactttgt gcgctctaaa gaataggata
     2461 actacaacct ctaattttat cattttatgg aattaaacaa gatctttaaa gacggtcttt
     2521 ggagcagcga aatcaacgtc agagatttcg taagtcataa catcactccg tattacggag
     2581 atgcttcatt cctcgaagga cctacagaac gtaccaaagc cgtatggaac cgctgcctcg
     2641 aagcactggc agaagaaaga gaaaacaacg gtgtccgctc attagataat gttaccgtat
     2701 caaccatcac ttcccacaag gccggatata tcgacaagga aaacgaactg atcgtcggcc
     2761 tgcagacaga cgaacttctg aaacgtgcca tcaagccttt cggaggtatc aacgtagtca
     2821 gcaaagcctg tcacgaaaac ggcgtggaag tggacgaccg cgtaaaagat attttcactc
     2881 actaccgcaa gacgcacaac gacggagtat tcgacgtata tacggaagaa atccgttcct
     2941 tccgttcgct gggattcctt accggacttc ccgacaatta tgcacgcgga cgcatcatcg
     3001 gtgactaccg ccgtatggca ctttacggca tcgaccgtct gatcgaagca aagaaggaag
     3061 atttgcacaa cctcaccggt ccgatgacag aggcccgcat ccgcctgcgc gaagaagtgg
     3121 cagaacagat caaggcactg aaagacatga aagtgatggg cgaatactac ggtctcgacc
     3181 tgagccgtcc cgcttacacg gcacaagaag ccgtacagtg ggtatatatg gcttaccttg
     3241 ccgccgtcaa agaacaagac ggtgccgcca tgtcactggg taacgtttct tctttcctcg
     3301 atatctatct ggaatatgaa ctgagcaaag gaaccatcac cgaatcattc gcgcaagagc
     3361 tgatcgacca gtttgtcatc aaactgcgta tggtccgcca cctgcgtatg caatcataca
     3421 acgacatctt tgcaggcgac ccgacctggg taaccgaatc tctgggcgga cgtctcaacg
     3481 acggacgtac caaagtgaca aagacctcct tccgtttcct gcagacattg tacaacctcg
     3541 gcccttcacc ggaaccgaac ctgaccgtac tctggagccc ggaacttccg gaaggattca
     3601 aagaattctg tgcaaaggtt tctatcgaca cttcttctat ccagtacgaa aatgacgacc
     3661 tgatgcgcga agtacgtcag tccgacgact acggaatcgc ctgctgcgta tcataccagg
     3721 aaataggtaa gcagattcag ttcttcggtg cccgttgcaa cctggccaaa gccctgttgc
     3781 ttgccatcaa cggcggacgt tgcgagaata ccggtacagt catggtgaag aacatccccg
     3841 tactgaccag tgacacgctg aagttcgaag aagtaatgga caactacaaa aaagtgctga
     3901 ccgaaatcgc ccgcgtatat aacgaagcga tgaacatcat ccactatatg cacgacaagt
     3961 attactacga gaaggcccaa atggctcttg tagatacgaa cccgcgcatc aacctagctt
     4021 acggtgtagc cggactttcc atcgccctcg attcactgtc tgccatcaaa tatgcgaaag
     4081 taactgcccg ccgcaatgat atcggtctga cagaaggctt cgacatcgaa ggagaattcc
     4141 cttgcttcgg taacgacaac gacaaggtag accaccttgg cgtagacctg gtatacttct
     4201 tcagcgaaga attgaagaaa ttgcctgttt acaagaatgc ccgtcctacc ctctccttgc
     4261 tgactatcac ttccaatgtg atgtacggca aaaagaccgg tgctactccc gacggacgtg
     4321 ccaaaggtgt tgccttcgct ccgggtgcca acccgatgca cggacgcgac aagaatggtg
     4381 cgatcgcttc tctgagttct gtagcgaaac ttcgttaccg tgactcacag gacggtatca
     4441 gcaacacctt ctctatcgtt ccgaaatcac tgggtgctac ggacgaagac cgtatcgaga
     4501 acctcgtaac gatgatggac ggttacttca ccaaaggtgc ccaccacctg aacgtaaacg
     4561 tactgaaccg tgatatgctg tacgatgcca tggagcatcc ggaaaactat ccgcagctga
     4621 ctatccgcgt ttccggctat gccgtaaact tcgtgaagct gagccgcgaa caccaactgg
     4681 aagttatcag ccgtagcttc cacgaacgta tgtaatctat tactctatat gatgataaac
     4741 gtacattcat acgaaagtat gggaacattc gacgggccgg gcttacggct cgtcgttttt
     4801 cttcaaggat gcaacttccg ttgtctctat tgcgccaatc cggatacgat agcaggaaag
     4861 ggaggcacgc ctaccccacc ggaagaaatc gtccgcatgg caatgagcca gcgccccttc
     4921 ttcgggaaac gaggaggaat cactttctcc ggaggcgaac cgacgtttca ggcgaaagca
     4981 ctcgtcccgc tggtccgcga actgaaagaa aaaggcatcc atgtctgtct ggacagcaac
     5041 ggaggacttt ggaacgaaga cgtagaagaa ttattcagac tgaccgatct tgtgttattg
     5101 gatataaagg aattcaaccc taaccgccat caaacgctca ccggaagaag caacgagcaa
     5161 accatccgca cggccgcctg gctggaagaa caggagaaac ctttctggct acgctacgtg
     5221 ctagtgcccg gatacagcga ttttgaagaa gacatacgcg cactgggaga agcactcgga
     5281 aaatacaaga tgatccaacg ggtggaaata ctgccttacc atacactggg cgtacataag
     5341 tacgaagcga tgggacagga atacaagatg aaaggggtaa aagaaaatac ccccgaacag
     5401 cttgaaaaag ctgcggaggt attcaaagag tatttcacta cggtggtagt taattaatgg
     5461 agaattctcc aatgacctca aagcaagggc attctttaat ccgttcccaa ggatctacga
     5521 tcccattata gttggtgtcg ggacttaaat cccgatgccc tactacttta gcttccggat
     5581 aacgctgcaa caattcgtgt accaagcgat gtagcgcctc cttctgacgg ggtgtacgcg
     5641 tatccgcagc ttttccattc tcatccagac cgccctcata acatacacct aagctgatcg
     5701 cattatagcc acgtgcatga gctccgaccg tatctttatc ccgcatcggc tcaatctcgc
     5761 ccgacttgcg tatataataa tgataccccc agcacgaaaa gccacgataa cggtgagccg
     5821 tatccacatc ctttgccgta aagtcgcaat cgacacgggt ggcggaacaa tggatcacaa
     5881 tcagactaat ctttctcatg ttccttttcc ctttccgtcg ttttcacttt gcacacctcc
     5941 ttacaagtag tatgatagcg cacttctctc accaccctgt cccgctttct ctttccgaag
     6001 aaaggaatca gatacatgat cacatctaaa atccgactta ctatttcttt catcttatca
     6061 aaatattaat ggaagttatt ctaattcgtt attaccttga cccgtctgcc aattataccg
     6121 tagggtccgg agcctcttca tcaccggagc catcaccacc ggaatccgga ttcttgtcag
     6181 ggtcttctcc cccgccatcg cctgcacccg cctgcgccac cgcacgagtc tgcacttgct
     6241 gataactcag aatcttcatc aactccgcca gcgtcttacc ggggcggaaa ataagatgcg
     6301 cccccttaat cattgaaccg gaaaattcct tgaccgatgc cgcaccttca ctgttgagtc
     6361 ctatctgcaa actgcccaaa tcgcccagtc tcgcaattct tcctgccttc aacgcacgct
     6421 tcacttcgta aagaataccc gaaatagccg cacgtacatc cgtttccgta caagtagaac
     6481 gactggtgat cgcttcgcac aactcttcaa agtccaactc tcccgacgcc tgcgcctgtg
     6541 cataatactt tgccggttcg ctcttttttg caggattctt gcgcggcacc actgaataag
     6601 atactgtcat tgccataata aaataatttt aaagtttata atacatagga tgcatcccct
     6661 tcttgttaac agcacaaaga taaggatagc cggacaagcc atattcccca acgaagtttc
     6721 ttgattccca acgaataaaa acgaagtcaa acctttgaat aacaaggaat tttatgtaac
     6781 tttatagcat aaaacaagaa gaaaacatca tgaattacaa agaagattct ttccttatcc
     6841 gcacctatac caaagcggaa ctggctcacc tttacaatcc ccatgtctgc ctcaaagttg
     6901 ctttacaaat acttcgtcgt tggattattt acaacctccc tctcctgcac gaactcgaac
     6961 aggaaggcta ccgcgcacgc aaccgtctcc tttcgccgaa acaagtggca actatcatac
     7021 actttttggg cgaaccgtag taacttattg ccattttata caaagttcct ttacacattt
     7081 ccgcaaagaa gttcctttgc atcgacaaac aataatcaaa ataaaaatga aacatttcac
     7141 catatttcaa ggtttctact acgcaatagc agagatgacc gaagaagaaa tagtgtccac
     7201 tatcggcagt tttacctacc gggaaaaagt cgaagaaata cgccgcatct ttgcagagca
     7261 aggagaaaag gctgccaatg agaagaaaaa agaattgccg gcaatcgcct tctccgccag
     7321 ctaccgagga aggcgtacca aagtgaacct cgtcaaatat ctgggacaca tcgtgataga
     7381 catcgaccac ctcagcaaag aagaattggc acgcatcctc cctatcatca agagatgcga
     7441 ttacacccgc atcgccttta tcagccccaa agggatgggc gtgaaaatca tagtacgcgc
     7501 atgccatccg gatgagacat tgcccgaaac ccttcaggaa atagaagact tccatcatgc
     7561 agcttacacc agactcgttt ctttttacac cgaactctgt cagatagaaa tcgacacctc
     7621 cggtcaggat gtggcacgca cttgtctgtt ctcttacgat ccggagattt atttcaatcc
     7681 gaacgctgac gcttttcttg tagatcaacc tcaggcatcc tacaaggttt caaatcgtaa
     7741 aaatctctcc ggcagtaaac aacagactcc tccggacggc cccccgacga atgaagacac
     7801 agcgctcaac gcccattccg ccaacgcttc tctggtgctg actttaacct actatcacaa
     7861 caagtccgaa aaatacatag tgggcaaccg gaacaattat ctgcaccatc tctcatgtac
     7921 cttcaatcgc tacggcattc cgcaggagga agcatccgcc tttatcaaaa gccagtttac
     7981 agactttccg gcggacgaga cagcctcttt gatcaatagc gcctacgctc ataccgacga
     8041 atttaatacc tgtaagctaa atggcacgca gaaacgaata ttacggatag agcaatatat
     8101 cagcgagcac tacgaaacac gctacaacga agtgctgcat atcatggaat atcgcagaag
     8161 gcatcccgac accgagaaac cggagccttt ccgcatcttg gatgagatga tggaaaacag
     8221 tatctggata gaaatcaacg aactgggata tgcctgcact gtcaaaacaa tcgaaaatct
     8281 gatttactcc gatttcagcc agtcgtatca tcccattcgc gagtattttg aattactgcc
     8341 cgaatgggac ggaaccgact atatccgtat cctggcggat agtgtccaga cgagtcatca
     8401 ggagttttgg gcggaatgcc tggaacgtta tctggtggcg atgtgcgcag cggctactca
     8461 agagaatatt gtcaatcaca cggtacttct gctatgcagc gagatacaga acataggaaa
     8521 gactaccttt atcaataatc tcctgcctcc cgaactgcgt gcttatctct ctaccggact
     8581 aatcaattcg aacaataaag atgatttagc caaaataacg caggccatgc tgatcaatct
     8641 cgacgagttt gaagggatga gcggtcggga actgaatgca ttcaaagatt tggtaacgcg
     8701 caaagtgatc agtttccgtc tgccttatgc acgccgttcg caaaacttcc ctcatacggc
     8761 ctcttttgca ggaacctgca attatcagga agtgcttcac gacacgacag gcaaccggcg
     8821 tttcctttgt tttcatcctt attccatcca atttattacc atcaattatg cgcagctcta
     8881 tgctcagatc aaatatctgc tgaataagcc gggatatcaa tactggttca cgcaagcgga
     8941 caatgaacgg cttgaagaga ataacgaggc tttcatcttt cattcaccgg aagaagaaat
     9001 ggttcttacg catatccgca agccggaacg tttcgagaag gtttattatc tgactgtcag
     9061 tgagattgcg gaactaatac gtgagcgtac cggttatcag tattccatcg gatcaaaaat
     9121 acagttgggg aaggtgatga ctaagcacca ttttgaatct aaaaaaggaa ataacgggcg
     9181 ccgatatgcc gtatttatta tagatatcga gcaggtaaaa tcaaacaggc tgtatgaata
     9241 gaagcgggaa agccttgtga atatagcaaa atgcagagtc atcttgacag atactctgca
     9301 tttattgttt ttacaaaatc attgaaaatt cgattttaca gcctaacgca ttcattatac
     9361 gatagaaagt agatacttta ggctctgtct gaccactttc tactcttgaa atataagaac
     9421 ggtcagagcc gatacgccgg gctaattcag cctgagtgat tttagccttt tttcttgcgt
     9481 cctcgataat ctgtcctgta taaaaggcgt aggccttttc ttctgcctct gcacgagaag
     9541 ctgttccttc cttaccaaaa cgctcatcta ttaatgcact gacattaaag aattcctcat
     9601 ttgtttttgc ttccataata ctcctttctt aatatctttg ctttatcaat ttctttcttt
     9661 ggtgtttttt cggttttctt ttgaaaaccg ttaaacagaa tcacaatacg cccttcgtcg
     9721 aaacaaaaga atattctata tatattgctt tggtactcga tacgaagttc ataaagtcct
     9781 tcttctatca accgcataaa tttcaaaggt attctgtctt gtgtctgcaa taacattagc
     9841 acatacaata tcttatcttg ggtgccagca tctaaatttt caaagaattc tttgaagtat
     9901 cctttatatg ctattatttc tcttttcata acgcaaatat aaggaatgtt gttcaactat
     9961 acaacacatt tcctcgtttt atattatttt tcatcatctt cacccccaaa agtgagagga
    10021 gtgagagagg aattgaaact ttttctattt tatttcttta tttctacttt ctatatttct
    10081 ctaaaaaaaa atacgaatgt tagaaatcct ctctcactcc tctcactttt taccttttct
    10141 ttctccaaaa agacggcgga aaatcggaaa aacacaaccg tcttttttca atttcccacc
    10201 gcattttcaa atcagcccac caattgaagc agacttcagg aaatatttgt catctttgat
    10261 gtgcaaaaga tcaaaagaat cagatatgga caacttgatg cgtaaacttc ctattggaat
    10321 acaaaccttt gaagatatac gaaggaagaa tatcttattg taaagatcgg aatggaattt
    10381 agtgcagaaa gccggaactt aaatcgttgg ttaatcgaag tgataggaaa gtaaaatatg
    10441 aaaaaccgaa ggattaagat atccttcggt tttttcgact atatacccat gattggtttt
    10501 acgatttcaa tcttcaatcc taatgcatta ataattcggt agaatgttcc tacacttgga
    10561 tttatagctc cgctttcaat acgtgagata tacgatttag ttgcattgat tctctttgct
    10621 aattcagact gagttacttt tgcttcccgt cgtgcatcca acagtatttg accagtataa
    10681 aaagcgtatg cctcttcatc gaacttttca cgttccggag tcccaggtgc tccgaactcc
    10741 ttatcaagtt ctgcgctgat atcagtcagc atgttgtttt ttgtactcat aatattcctc
    10801 ctttattttt aatgccttat ctatttctga tgatggggtt ttctgtgttt tcttatggaa
    10861 gccattaaat aaaacaacta tttgcccttc atcaaaaatg aaaaagatac ggtaaatgtt
    10921 tccgttatat gatatacgta gttcatatag accatcacgt ataaccttta taaattttat
    10981 aggcaaacgg tcttctgttc caagcaatga aagcacatat ttcacttttt gaatttcctt
    11041 ttctgtcaga gtggcaagaa aatccttgta gtattgaccg tatgctatta cttttcttct
    11101 cattgtgcaa atataataaa agtttcaata tcatacaact tttaaagtcg aatttatact
    11161 gctaacgggc ttaaattccc tctcgggtac tcattttatt cgaatttccc ttccgaataa
    11221 tctgaaaact ccccggcacg ttctttcttc tcatacgaga ccaacgtttc gatactgagc
    11281 gctttcccgt tcttagggct tatgacatct atcacacttg acaaggaccg gaacgtctgt
    11341 tcgcaattcg cgtctccatt atacgtcaac ctcccccggt caatggcacc tagaataaca
    11401 gaaacatacc gtttcggatc tccccgatat tcgataacag tgggcgtcat ttgttcttct
    11461 tcccgaatca gttggacgac aattcttttt tttggtcaat cagctccaac agttttttac
    11521 tatgcacact gatttgtgca tctacttcac gaagttcatt cttcaatgaa caaaacaatt
    11581 catcactcaa tgaattttcc ataaaaacga tttttattaa ttataaaaaa gccattccgg
    11641 aaagcacagc tattgcctgc ttcccgaaat ggtgactaat accttcaaaa acaatgactc
    11701 tatttttact ttaatgtact caatttattt cacttctttt ctctcctgca ttccaaacca
    11761 acaaagcaaa cactactgaa agcaaggctg caccaatcca aaaacaattg atatatgtaa
    11821 aatcgtaaac ttctactcca ttttgcaccg tcttctgacc ttcgatcaga atgccactca
    11881 tcacatcctg caaaccggct cctatataac tcgctatacc gacgactccc aaagcggctc
    11941 ccgaagcatt gctgggagca atatcgacag ccatcagtcc tcctaaaaaa caaatcagca
    12001 ctccaatgcc caaaccgaag agcaccatcg ccaaagcatc caccccaaaa tgtacccccg
    12061 gaaccaatag aaacaaacaa agagcagaca cattcattaa tccgaatatc aaagccggaa
    12121 cattacgact gccagcaaaa aacttatctg aaataatacc tgagaaaacc gtacctacaa
    12181 ttccgcatac agaactgata gatataataa aactagcatc caaagtagaa taaccttttt
    12241 gcgcttccag atagaaaaca ccccagctat tgactgcata acggctgata tacataaaag
    12301 cactggataa tgcaagaatc caaatagcag gattcttcaa aactgctttc tgagctttat
    12361 tgaattcctc ggtttgctta ccggaaacgg aatgagcatc tgacgtcccc caccgatcta
    12421 gcaaaaagcc ctgactttga ggcgtatcac gcataaaagc aagcatcatc agaaaaccaa
    12481 gcaaaccaat cactcccgca ccgatcatcc cataacgcca tcccatccaa ctgaccagca
    12541 aagcgatgga tataaaagtc agagcttcac ccaaattgtg gctggccgac caaaagccat
    12601 aaaaagtacc tcgctcttta ctactatacc aacgagtcag cgacacaact cctgatgctg
    12661 cccccatcga ctgaaaccaa ccattcaacc cccaaaggag aacaaaagca aagaaggaat
    12721 tcgtgaatcc cagacataag ttgatcagag cagaacacaa taatccggta gacataaaac
    12781 gctttacatt gctacggtca gcaagaaagc cattggtcag cttaccgacg gcatatacga
    12841 aaaaaaggca ggaaccgata atccccagtt gggtttcggt aaaaactccg tcttctacaa
    12901 tcggtttacg gattacattc atactcaaac gacaaacata ataaatgcca tatccggtag
    12961 tggcagacag aaaggtagcc caacgaatac gcttgaaacg gacagagcgt tccggatcag
    13021 tctctccccc ggacaccgga ggagagattt tataaaaatc caatagttta aatcccataa
    13081 agaagtctat attttaatga tacgcatctt ggccgttttc actacgcttc ttacgcgatt
    13141 gcaaatattc cagcagatag gcagtacggt ctgtctgaat gatggccgct ccgagtgtat
    13201 cgatcagata accatatcct tcgtccggat tctccaacga tttatcatca tcatgtccgc
    13261 cagccatcgt atcccacaac gtattatacc agattttact ttttcctttc aacttcgttt
    13321 ttacttgctt gggggcctgg caggtatccg atacaaatag aagttcaaaa gctacgggat
    13381 gcagctccgt cataaaatca tccagttgct tcattgctcc cggcttatcc aaatgaatga
    13441 taggcatata aatgatacgg tccagatatt tacctaagtc tttctttacg tctgccacag
    13501 gcttggaacc tttcatgata atctgatcca ctgttcccgt cttttcgagg atgggaaaaa
    13561 tctcgtcaaa tatcggatat gctttatcca gattgaccat cacacgacct ttggcaaccc
    13621 ataaagcctc ttccaaagta ggtacacgat gcttggtttt gagtgccgct ccatttttca
    13681 gatagagtgt ccggatagaa tccaatgtcc attcggctac ctttcctttt ccggtagtcg
    13741 ttcggtccag cgttttgtca tgcatcagga tcaattgacc gtctttggtt ttctgaacat
    13801 ccagctccac tacgtcagct cccagacgaa tggaactttc aatagcggca agtgaatttt
    13861 cgggtgcgta acgccagtct gcccgatgag ctacaaccgt gatttcttta ttgtcagggt
    13921 tcgttatctt cgcataaatg gctttcaccg gttcgtctgc cgacaggcag aaaggaaatg
    13981 cgaataagat tcctatcatt atatatttct tcatatctat atgtactatt atctgtatcc
    14041 tttagacttt aaatatttgg cagctacttc agcatagtct gtttgcacaa tgttgatgcg
    14101 tttgttaatc attcccacca aaccggagta gttttccgac aacatattgg tatcattcgc
    14161 tccgacaatg ttggagaaaa gaagccagcc tttatcttta atctcattaa ccatcgttcc
    14221 acccatagca tctgacgtag acagctgcat catttgtaca ttatcagtgt aggatgagga
    14281 gaagtatgtg atgtcatcgg tagctttcgc catcgggtgc aacagcaaac tactgttggc
    14341 tgccttcaaa tcaaatgcat aattgcgatt gttggataca tacagcaaag tggaaccttc
    14401 catatccaat tttttaagca atgcgacgat cgtatttacc gcaacattct tgttgacaat
    14461 atccagatta taataaactt ttccttttcc tttcttcatc gcttcctcca aagtcgggat
    14521 tcgttcgcca gttatattgc cggatgcatc tttcagataa aattgttgta attgctgata
    14581 agtaaagtct cccaccgcac cgctaccgtt tgttgtccgg tcgatggtgt tgtcgtgcat
    14641 caataccaac acaccgtcag aggtcggccg tgcatccagc tcgatcatct caactcctgc
    14701 tttgaccgag tgttctatcg caggtaacga gttttcggga atcccctctt tcatcccttt
    14761 ttgggtattt ccacgatgcg cgcagagcca cactttataa gaggtgcttt caaacagact
    14821 ctttaaatct gctttcaaat tccccgtcac aggcaactgt cctccttctt ctccaccggg
    14881 attctctcca ttccctcccg attgggctcc ggagtgacgt ctgtccttcc ctttcatcgg
    14941 ccaggcagag gttgcggccc cggtaattcc ctcatcttcc aaagctacca acacgctctt
    15001 tgtagggtcc accgtattgg tgactccgat ataaatcgct ccatccggtc cgatggtagg
    15061 cgaactccag attttaccga ttcccgcttc ccaatctcct tttaaaggag agtcactttc
    15121 actaatcaac gcagcaaggt cttttttcag aatcaattgt tcatccgatt cttccggttt
    15181 aatgatataa taattgccgg actgggtgcc gaaatgtatg tttcctgctt gatcaattgc
    15241 cgcacaaccg cttacatctt ccgcaatgcc gtaatgccat tggatagctc ctcccggaga
    15301 caaagagatg attcctccgg ttgcttcccc cggagcacgt ttcactgtaa cgataatgct
    15361 tccgtcgagt cctatcacaa caccgccttg atccagcgtg ccgacattgc ccaaaggagt
    15421 acgccacttc tccactccat cacttcctat agcaaat
//
