LOCUS       c00031_gnlPro..         9337 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AILKLODE_31.
ACCESSION   c00031_gnlPro..
VERSION     c00031_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:28:07
            Original ID  :: gnl|Prokka|AILKLODE_31
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9337
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9337
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4307]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4307
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9337
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9337
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2..187
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_1"
                     /sec_met_domain="Glyoxalase_4 (E-value: 8.9e-12, bitscore:
                     34.8, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GIHHIAFAVPDVQAALDEAESKGVKLIDKAPRGGAEGLNIAFLHP
                     KSTCSVLTELCMPGKK"
     CDS             225..1778
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_2"
                     /sec_met_domain="CT_Btheta (E-value: 8.4e-293, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKFLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     ESLAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEEGLQLIRKLLSFLPQNNLEETPLIECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAASEDPAKATA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             1801..2688
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_3"
                     /sec_met_domain="OAD_gamma (E-value: 1.3e-12, bitscore:
                     37.7, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNKRFGVLLLFILLVSFGAQAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCFLTDDKNNPKKYPIPKGDVLTQIPPHQHTLFWADGEP
                     NRGTFHVNFTLDPSKENYIALYDADGKSLIDEXXXXPAAQKPDVSYGRIIDGKEEWAQL
                     TKVTPSTNNLTLDSNEKIENFKTNDSLGIGMTITAMAVVFLGLLLLFLIFKQVGKAAIA
                     ASKRNAQKAGAPVNVNTPDEVSGEVFAAIATALYEMSDDNHDIEHTVLTIRKVRRAYSP
                     WSSKIYSLRETPRK"
     CDS             2711..3142
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.9; E-value:
                     3e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_4"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.8e-21, bitscore:
                     63.9, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTTASGEPVVTRPAASTTQGAVKTPLPGVILQIKCNVGDTVKRGQTLLI
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             3147..4307
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_5"
                     /sec_met_domain="OAD_beta (E-value: 3.6e-154, bitscore:
                     502.3, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLSFLGDNLQLFLTYTGVYNATPGHIIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYIIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKQGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             4811..6556
                     /locus_tag="ctg31_6"
                     /transl_table=11
                     /translation="MSQVKGIPYGISDFKRLRNENFYYVDKTMYLPLIEKMPSYLFLIR
                     PRRFGKSLFLSLMRTYYDILQKDNFEKYFGDLWIGSHPTDQRNRFQVLYFDFSKAGCSQ
                     PGTDMMTSFNDYCGLIINQFAHEYASYYDADYKATIENIASAKAKLSYIEIKAKEKGYP
                     LYLIVDEYDNFTNVILSEHGQKMFHDLTHASGFYREYFKQFKGMFDRIFLMGVSPITLD
                     DLSSGYNIDWNISTDETFNAMMGFDETDVREMFHYYRQNDMLTGDIDTMIAEMKPWYNN
                     YCFARMALDSDRVFNCDMILYYLHNQVNFHRAPEEMVDKNICINYSKLKKLTGINHKSL
                     HEDSCMNTIKDIVAKGEVLVDLHTSFPAEKVMDIDNFRSLLYYYGLLTMCGTHGKLLKM
                     CIPNNCVREQYFGFLRDYYQQFHTINLSHLKDLIDDFAYDGQWKPFFESIALAYRENSS
                     VRDAMEGERNLQGFLKAYLALASYYLVEPELEMNYGYCDFFLLPDKKRYPDIGHSYILE
                     LKYAGRTTTDTELETQAEEGRXXXXLQYSKDKIALQLAQDTTLHLILLQFRGWDLVKCE
                     EIASC"
     CDS             complement(6888..7391)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_7"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.6e-22, bitscore:
                     69.9, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LRPINPVDEQRSSIEKYLSLVNRQLSTIMSCILNIETSTSVCSVA
                     LSADGEVLFEKSSFEGPSHAALLGVYVEEAIAVTKEKGLKLDAVAVSSGPGSYTGLRIG
                     VSVAKGLCFGYGIPLISIPTLEVLAVAALEQQNNASDCLYCAMLDARRMXXXXXCMQLS
                     MMLI"
     CDS             7531..8391
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMQI
                     RSQLLQSLERGKVDFSIYIEYIGKDTPTQINLTAFESYYSQVKDIAEKLNIALPADWFQ
                     TLLKMPDVIKSEIVEVDESEWEVVFNAVKGAIKHLCDFRIQEGAMLQKLFEDKIGNIAR
                     LLTEVEEYEGERIEKIKARIMDNLEKVANQDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMKDGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             8393..8962
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINHLLKQNLNLHFSISATSRAPRGTE
                     QNGVEYYFLTPDEFRARIAAGDFLEYEEVYTDKYYGTLKSEVERQLNEGNNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPSIAHLRERLEGRGTDAPEVIDSRIAKAEFELGFIPHFD
                     VCIVNDDLATAQAEAVEVIKDFLSKE"
     CDS             8959..9150
                     /locus_tag="ctg31_10"
                     /transl_table=11
                     /translation="MNNNRQLSRKWGYIFALTGIAALGTCIAGLIYKEYLXXXXXXXAT
                     GLVFGVQAFNFIMWKKQR"
ORIGIN
        1 aggtattcac catatcgcat ttgctgtacc tgatgtacag gctgcattgg acgaagctga
       61 atcaaaaggt gtcaaactga tcgacaaagc tccccgcggt ggtgcagaag gtctgaacat
      121 tgcattcctt cacccgaaat caacttgcag cgtattgact gaactttgca tgccgggtaa
      181 aaaataatta atcagttcat ttctaacaac aaatcagaaa tacaatgagt aaccaacttg
      241 aaaaagtaaa agagcttatc gctcttcgcg aacaagcccg tttaggtggt ggagaaaaaa
      301 gaatcgaatc tcagcacaag aaaggcaagt acacagcacg cgaacgtatc gccatgttgc
      361 ttgacgaagg tagtttcgag gagtttgata tgttcgttca gcaccgttgt actaacttcg
      421 gtattgaaaa aacaaaattc ctgggtgatg gtatcgtaac cggatatggt acgatcgacg
      481 gccgtttggt ctacatcttc gcacaggact tcaccgtatt cggaggagct ttgtcagaat
      541 cactggccat gaagatttgt aaggtaatgg atcaggccat gaagatgggt gcccctgtca
      601 tcggcttgaa cgactcaggt ggagcacgta tccaggaagg cgttaacgct ctggcaggat
      661 atgctgaaat cttccagcgt aatatccttg catccggtgt tgtacctcag atttcaggta
      721 tcttcggtcc gtgtgcaggt ggcgcagttt attctccggc gctgactgac tttaacatca
      781 tgacacgtgg taccagctac atgttcctga caggtccgaa agtagtaaaa accgttaccg
      841 gtgaagacgt aactcaggaa caactgggtg gcgcaagcgt acacacaacc aaatcgggtg
      901 ttgcccattt cgctgtcgac acagaagaag aaggtctgca actgatccgc aaattgctca
      961 gcttccttcc gcagaacaac ctggaagaaa ctccgctgat cgaatgcaaa gacccgatcg
     1021 accgtctgga cgatgtattg aacgacatca ttcctgacaa cgctaaccag tcatatgaca
     1081 tgtatgaagt aatcggcaca atcgttgaca acaacgaatt cctggaagta catgctgatt
     1141 atgctaaaaa tattattgtt ggtttcgcac gtttcaacgg ccagtctgtt ggtatcgtag
     1201 ctaaccagcc gaaagtaatg gcaggctgtc tggacagcaa cgcttcccgt aaggcaggcc
     1261 gcttcgttcg cttctgcgac gctttcaaca ttcctttggt aacattggta gacgtaccgg
     1321 gattccttcc gggaacaggc caggaataca atggtgtaat ccttcacgga gccaaattgc
     1381 tttacgctta cggcgaagca actgtgccta aaatcactgt tacattgcgt aaatcttacg
     1441 gtggtgctta ctgcgtgatg agttctaaac acctgcgtgg cgatatgaac tacgcatggc
     1501 cgacagcaga aatcgcagtt atgggcccga gcggtgctgt agaagttatc ttcgcaaaag
     1561 aagttgccgc atccgaagat cctgcaaaag caacagccga aaaagaagca gaatacaaga
     1621 aagcattcgc aaacccgtac aacgcagctc aatacggtta tatcgacgat gtgatcgaac
     1681 cgcgtaatac ccgtttccgt atcattcgtg ctttacaaca attgcagacg aaaaagttaa
     1741 gcaatcctgc taagaaacat gacaatctgc ctctataatt cttaaaacag gaaaatgaat
     1801 atgactaaca aaagatttgg agtattgctg ctgttcatcc tgctcgtatc attcggggca
     1861 caggcacagc gtgcaacctc catgcgaata aatgaagtgc tggtcatcaa cgaagataat
     1921 ttcgttgacg actatggcaa acgtcacggc tggatagaat tattcaatac ttctgccgga
     1981 acggttaata ttgcaggttg tttcttgaca gacgacaaga acaatcctaa aaaatatccg
     2041 atccccaagg gtgacgtact aactcagatc cccccccatc aacacactct gttctgggcg
     2101 gatggtgaac ctaaccgtgg tacttttcat gtcaatttca cgttagaccc gtcaaaagaa
     2161 aattatatag cactttatga cgccgatggt aaatccttga tcgacgaaan nnnnnnnnnt
     2221 ccggctgcac aaaaaccgga tgttagctat ggtagaatta ttgacggaaa agaagaatgg
     2281 gcacaactca caaaagtgac tcccagcaca aacaacctga cgttagattc taacgaaaag
     2341 atcgaaaact ttaagacaaa tgactctttg ggtatcggta tgactattac agctatggct
     2401 gttgtttttc taggcttgct ccttcttttc ctgatcttca aacaagtcgg aaaagcagct
     2461 atcgcagcca gcaaacgtaa tgctcagaaa gcaggggcac ctgttaatgt aaatacaccg
     2521 gacgaagttt cgggcgaagt ttttgcagca atcgctacag ctttgtatga aatgagtgat
     2581 gacaatcacg acatcgaaca tacagtgctt acaatccgca aagttcgccg tgcatattct
     2641 ccatggagtt ctaagatcta tagtttacgt gaaactccca gaaagtgatt atctctaaaa
     2701 acaaacaaga atgaaaagtt ttaaatatac catcaacggt aacgtatata aagtacacat
     2761 caattcagtg gtcgacgata tcgctgaagt agaagtaaac ggtactcctt ataatgtaaa
     2821 aatggagaaa ccggcgaaaa aacaaatggt tacactcaaa cgcccggcac aggctcctac
     2881 tacagccagc ggcgaaccgg ttgttactcg tccggcagca tctacaaccc agggcgccgt
     2941 taaaactccg cttccaggtg ttatcctgca aatcaaatgc aatgtaggcg acactgtgaa
     3001 gagaggacaa actttactta tcctcgaggc tatgaagatg gaaaacaaca tcaacgctga
     3061 ccgcgacggt aagattattg aaattaaagt acataaggga gactccgtac tggaaggtgc
     3121 tgatctcgtc gtaatcggat aagagtatgc aagagagttt tttatcattc ctgggtgaca
     3181 acctacagtt gttcctcacc tatacaggag tatataatgc aactccgggc catatcatta
     3241 tgatattggt tggtttgctc tttatattcc ttgcgattaa atatgaattt gaacccatgt
     3301 tgctgatccc tatcggattc ggtatcctga tcggtaacat tccttttaaa gatgcagggc
     3361 ttcaggtagg tatctacgaa caagggtctg tacttaacat cctctatcaa ggggtaacct
     3421 ccggatggta tccgccgttg atcttcctcg gtatcggggc gatgaccgac ttctccgctt
     3481 tgatttccaa tccaaagctg atgttgatcg gtgctgccgc ccagttcggt atcttcggtg
     3541 cttatattat cgctcttcag atgggattcg aaccgaacca ggccggtgct atcggtatta
     3601 tcggtggtgc tgacggtcct acggctatct tcctgtcttc caagctggcc cctaacctga
     3661 tgggtgctat tgcggtgtca gcctactcat atatggcgtt ggtacctatt atccagccgc
     3721 cgttcatgag actgcttaca acaaagaaag aacgtctgat ccgtatgaaa ccgccgagag
     3781 ccgtttcttc tacagaaaag atcatcttcc cgatcgtagg tctgttgctg acttgcttcc
     3841 ttgtaccttc aggtctgccc ttgctgggta tgttgttctt cggaaacctg ttgaaagaaa
     3901 gtggtgtaac ccgtcgtctg gctgaaacag cccgcggtcc gctgatcgat acaatcacca
     3961 tcctgttagg tatcacagta ggtgcttcta cacaggcaac tcagttcctg acactgaact
     4021 ctatcaagat cttcggttta ggtgcgttgt cattcgtgat tgcaacctgt gccggtgtat
     4081 tgttcgttaa gttcttcaac ctgttcctga aacaaggcaa caagatcaat ccgcttatcg
     4141 gtaatgccgg tgtatctgcc gttcccgact cagcacgtat ctctcaggtt gtaggtctgg
     4201 aatatgaccc gaccaactat ctgttgatgc acgccatggg tccgaacgta gcaggtgtaa
     4261 tcggttctgc tgtagcagcc ggtatcctgt taggattctt aggataataa aacaagtgac
     4321 agttgataga tggcaagtga cagataaata gaatcttttc taaatctgtc aactgtcact
     4381 tatcaactgt caacttttta tacattttgt tcgacctcca tcggatttgt ttccggatta
     4441 gttacttctt ccaatgtcgt ccccacaaac aaccatacca tcaaaaggac aatcgcaata
     4501 ataaccccga tgatcaacca tagatttttc tttttcatac cttcgtaatt ctgattttgt
     4561 tttatatgag cataaaacaa cagaaacaag tctttggttt aaaaagatct atgagtaaaa
     4621 tacgaaacct actgccatac tatcatagtt gacaaatatt catccgatta caaatgattt
     4681 agcaccatac tctcatacgc aattcatata ataatagact gtaaaacaca aagctggaat
     4741 actttctcaa acattgtttt atttgccgga ataaactaac tttgtctcta tatcttaaaa
     4801 agtatccaac atgagccaag taaaaggaat accatacgga atatctgatt tcaaacggtt
     4861 gagaaacgaa aacttttatt acgtagacaa gacgatgtat ctgccgctga tcgaaaagat
     4921 gcccagctac ttgtttctta tccgtcccag acgattcgga aaaagtctgt tccttagctt
     4981 gatgcgtacc tattatgata tattgcaaaa ggataatttc gaaaagtatt tcggcgattt
     5041 atggattggc agccacccga ccgaccagcg caaccgcttt caggtgcttt acttcgattt
     5101 ctcaaaagcc ggttgttcgc aaccgggaac cgatatgatg accagcttca acgactattg
     5161 cggtctgatc atcaatcagt tcgcacatga atatgcatcc tattacgatg ccgattataa
     5221 agctacgatc gaaaatatag caagtgccaa agcaaaactg tcgtacatcg agataaaagc
     5281 aaaagaaaaa gggtatccgc tttatcttat cgtagacgaa tatgacaact tcacaaacgt
     5341 catactgagt gaacacggac agaaaatgtt tcacgaccta acacatgcca gcggtttcta
     5401 cagggaatac tttaaacagt tcaaagggat gttcgaccgg attttcctga tgggggtcag
     5461 tcctatcact ttggatgatt tatcgagcgg ttataacatc gactggaata tctcgactga
     5521 cgaaactttt aacgcaatga tgggattcga tgaaacagat gttcgtgaaa tgtttcatta
     5581 ttaccggcaa aacgatatgc tgacaggaga catagataca atgatcgcag aaatgaaacc
     5641 gtggtataat aattattgtt tcgcacgaat ggcattggat agtgaccggg tgttcaattg
     5701 tgacatgatt ttgtattatt tacacaatca ggtaaatttc caccgtgccc cggaagagat
     5761 ggtagacaaa aatatttgca taaattacag caaactaaaa aagctaaccg gtatcaacca
     5821 taaaagttta cacgaagata gctgtatgaa tactatcaaa gatattgtcg caaaaggaga
     5881 agtgctagtc gacttgcaca cctctttccc ggctgaaaaa gtaatggata tcgataattt
     5941 ccgaagtcta ctttattact acggactgct tactatgtgc ggtacacacg gaaaactatt
     6001 aaaaatgtgt atccccaata attgcgtacg tgaacaatac tttggtttcc tgcgcgatta
     6061 ttatcaacag tttcatacaa taaacctttc tcatctgaaa gatttaatag acgacttcgc
     6121 ttacgacggc caatggaaac cgtttttcga atccatcgcc cttgcctatc gtgaaaactc
     6181 ttccgtacgt gatgctatgg aaggagaaag aaatctgcaa ggttttctga aggcatatct
     6241 ggcactcgct tcttattatc tggtagaacc ggaactggaa atgaattacg gttactgcga
     6301 tttcttttta ttacctgaca aaaagcggta tcccgatatc ggacacagct acatattgga
     6361 gttaaagtac gctggacgta ccaccaccga cacggaactc gaaacgcaag cagaagaagg
     6421 acgccnnnnn nnnnnattac aatacagtaa agacaaaatc gctttacagt tggcccaaga
     6481 cacaacactt catttgatac tgcttcaatt ccggggttgg gatttggtta agtgtgaaga
     6541 aatagcttcc tgctaacaat cttcaccgga tgatagcttt caaaacgcta tcatcccaac
     6601 accttattct tagcgattgt tgcctgaaat tctttcaggt agaacggctc gaaataagcg
     6661 acatcctcan nnnnnnnnnn nnnnnnnnnc ggcaaatgct ttttcagaca aggttatcat
     6721 attaacagcc agcgggtgga tattatcaat aaagagcgca ttcggagaag taatcacctc
     6781 ccgacatttg gctgcaccgt tcccaaagaa acaaactttc cctttttcca gccaggaagc
     6841 ataagtttct gcatctacaa tatcagcaga cgtttcgcga accgtcttca aattaacatc
     6901 atagatagct gcatacannn nnnnnnnnnn tccatccgac gggcatcgag catggcgcaa
     6961 tacaaacagt cggacgcatt attttgctgt tccaatgcgg caacagccaa cacttccagc
     7021 gtagggatac tgatcagagg tatgccgtaa ccgaaacaca aacctttggc gaccgatacg
     7081 ccgatacgca atccggtata agatcccgga ccgctgctga cagctactgc atccagcttc
     7141 aatccttttt ctttggtcac cgcaatagcc tcttccacat aaacacccaa caaagcagca
     7201 tgcgacggac cttcaaacga actcttttca aaaagcacct caccatcagc cgataaagcg
     7261 acggaacaca ccgaggtcga tgtttcaata tttaaaatac aagacataat agttgacagt
     7321 tgacggttga caagtgacag atatttttca atagaactcc gctgttcatc aaccggatta
     7381 attggtcgca aaagtacaaa aacgtcttta tacgaatgag aaaataacga actttttctc
     7441 tatcaggacg aagaattatc aactgtcaac tgtcaactat caactgaata agctatcttt
     7501 gcacaaattt ttagaacaat gatacaatca atgactggat tcggtaaggt tacagccgaa
     7561 cttccttcaa aaaaggtaac cgtagaaata aaagcactca acagcaaaca actggattta
     7621 tcaacccgca tcccttctat ctacaaagat aaggaaatgc aaatccgtag ccagctgctt
     7681 cagtcgcttg aacggggtaa ggtcgatttc agcatttata tcgaatatat aggaaaagat
     7741 actcctaccc agatcaacct taccgctttt gaaagttatt acagccaggt taaggatatt
     7801 gcagaaaaac tgaatattgc acttccggct gactggttcc agacattact aaaaatgccg
     7861 gacgttatca aatctgaaat tgtagaagta gacgaaagcg aatgggaagt tgttttcaat
     7921 gcggtaaagg gagccatcaa acatctttgt gacttccgca tccaggaagg cgccatgctg
     7981 caaaagttat ttgaagacaa aatcggtaat atcgcccgcc tgctgaccga agtggaagaa
     8041 tatgaaggcg aacgcatcga aaagatcaaa gcccgtatca tggataacct cgaaaaggta
     8101 gccaaccagg attacgacaa gaaccgcttc gagcaggaaa tgatctatta catcgaaaaa
     8161 ctggatgtga acgaagaaaa gaaccgcctc gacaaccatc tgaaatattt catcagcacg
     8221 atgaaagacg gacacggaca aggcaaaaag ctcggtttca tcgctcagga aatgggccgc
     8281 gaaatcaaca cgctcggttc gaaaagcaac catgcggaaa tgcagaaaat tgtcgttcag
     8341 atgaaagacg aactggaaca aatcaaggaa caggtactaa acgtattata atatggctgg
     8401 taaattaatt atattctccg ccccgtcagg ctcaggtaaa tcaaccatca tcaaccatct
     8461 gctaaaacag aacctgaacc tgcatttctc tatctcggca acaagccgtg caccgcgcgg
     8521 aacagaacag aacggtgtgg aatattattt cctgactccc gacgaattcc gggcccgtat
     8581 cgctgccggt gattttctgg aatatgagga agtatatacc gataaatact acggcacatt
     8641 gaaaagtgaa gtggaacgcc aactgaacga aggcaacaac gttatattcg atgtggacgt
     8701 tgtcggcgga tgcaacatca aaaagtttta tggtgaccgt gctctttcag tatttatcca
     8761 gccgcccagc atcgcccatc tgcgtgaacg tctggaaggt cgtggtacgg atgctcccga
     8821 agtgatcgac agccgtatcg caaaagcgga attcgaactg ggatttattc ctcatttcga
     8881 tgtctgcatc gtaaacgacg accttgcgac agcacaggcc gaagcagtgg aagttataaa
     8941 agattttctg tctaaagaat gaataacaac agacaattat cacgtaaatg gggatatatt
     9001 ttcgcactga ccggaatcgc ggcattggga acctgcattg caggcctcat ttataaagaa
     9061 tatctcannn nnnnnnnnnn nnnnnttgca accggactcg tattcggcgt acaggcattc
     9121 aactttataa tgtggaagaa acaacggtaa aggaaaacaa caaactgaaa accggaatct
     9181 tttccggttc tttcaacccg gttcacatcg gtcatttggc cctggccaac tggctgtgtg
     9241 agtttgcggg gttggacgaa ctgtggtttg ttatcacgcc tcataacccg ctaaagaaac
     9301 gcgacgacct gatggatgac cggctccggc tcgaact
//
