LOCUS       c00016_gnlPro..        13527 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMMBPPIC_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 03:13:21
            Original ID  :: gnl|Prokka|OMMBPPIC_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 41118
            Orig. end    :: 54645
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13527
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[51118:54608]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13527
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13527
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(469..1059)
                     /locus_tag="ctg16_44"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAVGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             1299..2909
                     /locus_tag="ctg16_45"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2973..3491
                     /locus_tag="ctg16_46"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESVDNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             3436..4365
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_47"
                     /sec_met_domain="adh_short_C2 (E-value: 4.8e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHAPSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4389..5594
                     /locus_tag="ctg16_48"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     EASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPSAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             5608..5808
                     /locus_tag="ctg16_49"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             5920..6054
                     /locus_tag="ctg16_50"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGISR"
     CDS             complement(6272..7012)
                     /locus_tag="ctg16_51"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRLRA"
     CDS             7187..7276
                     /locus_tag="ctg16_52"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKRKCIH"
     CDS             7307..8014
                     /locus_tag="ctg16_53"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGMEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8269..8676
                     /locus_tag="ctg16_54"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg16_55"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg16_56"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_57"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_58"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_59"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.2e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
ORIGIN
        1 ttctgtaatg ccgtgacatg gaacaagaaa atctcttgat ttctacttgc caccatttac
       61 attggtgcca gcaaacctcc gtggatgcgg aggttccagt agttaacaaa cactgtattt
      121 aattcgaatt atgaagaaca tcgctatcct cgccatcgcc ggcgccgctt gcctggtcgc
      181 ttcttgctcc cagcagcagc agcaacagca aaccaccgct cctgctcccg ctccggttgt
      241 gcaggccaag ggcaagtaag tttgcagcgg ggttttgccc tgcaacacta gcaaattatc
      301 caattaatcc gcactcggtg tacgcactga gtgcgttttt atttgccctg agtccggatt
      361 ccctccgcca tttgccgatt cgccgggatt ttccttaaaa acggcggata ccgcaaaccg
      421 ccgcggcgca gcaccgtgtg ccggttcctg ccggatcagg cttccccttt attcagcggc
      481 cgccttcgcc tcattctgct gatcggactg aaatatccgc tgaaccagca tggggcgttt
      541 cctggcccac ccgggccaga ccaggtgatg ttccatgccg taggaatggc cctccggaaa
      601 ggccttggaa acaaatggtt cccgccagtc ctcctcccat ttgccgcctt cccggtcctt
      661 ctgggtcagc gtcaccagat gcccgcagtt cttccaggca tccagaacaa tggagccctg
      721 caatcccttc cccacggcat tgacatacac gcaactgtgc tccctgcccg ttccacggtc
      781 tcgaatcgtc agccctatgc ggaaatactt cacggggcgg cggcgcaggt cccggtacaa
      841 atcctgctgg acctgccagc acagccccct gtcgcgcagg ttggaattga ccagaatatt
      901 gttcagccag ccaaacagca cagtcctgtt gtcccgggca atcgctgcgg actggaccac
      961 ggccgtgtcc gccagccacc tggcctccgc tccggcagcg ggaagagagg cctgatccgg
     1021 cggcagcagc gccaggaagg cattagccag cccggacatt tgctgctgca cgtaaggttg
     1081 ttgtatataa tcctccgccg gaggagtaca gcaggaactc catccgcaca aaagggcggc
     1141 agcaagcaaa agcctgaatg tctgcgtggt cggcatggcg cgccaaggct agcagactac
     1201 gcgtaaaaat ccagtaaagc tttcaaaaat gcctgcctcc gccctgacgg ctcttgcctt
     1261 cccctttcca tcccggtaga atacatcctc tcttcaccat gctgacgatc aaaaatctca
     1321 caaaatccca cgccggacgg accttgttca gggaaacgga aatgaccatt aactgggggg
     1381 aacgggtggc tctggttggc cccaacggag caggcaaatc caccctgttc cgcatgattc
     1441 tgggagaaga cacgccggac gaaggctcca tcagcatgga tgaatacgcc atcgtgggct
     1501 atcttcccca ggaagccagc gaaccgaagg atgaaaccgt tctggaaatc gccctgggca
     1561 tcacgccgga aatggaacag gccatccaca ccatccggac ggcggaaaac gccaacaaaa
     1621 cggatacgcc ggaatacgcg gaagccattg acaccttcaa cgccgccaac ggttaccagc
     1681 tggagcccaa agccaaaaaa attctcaaag ggctggcctt tcgggaaagc gacttccacc
     1741 gccccgcccg ggaaatgtcc ggcggctgga tcatgcgcgc gtacctggcc aagctccttg
     1801 tcctggagcc ggacctcctg atgctggacg aacctaccaa ccacctggac ctcctgtccc
     1861 tgctgtggct ccagcgatac ctgaaaaact accccggagc catcctgatg atttcccacg
     1921 accgggattt catggatgag ctggtggaaa gcgtgtacga catcgacaac gaagaactgg
     1981 tggaataccg cggcaattac tcggacttcc tccaacaaaa ggacgtgcgc ttcgagcagc
     2041 ttcaggcggc ctaccgcaac cagcagaagg aaatagcgca cattcaggaa tttattgacc
     2101 gtttccgctc catcaattcc aaagccgggc aagtccagag ccgcatcaag cagctggaaa
     2161 agatgaaaat cattcaaaaa ccggtagccc gcaggaaagt atttaaattc aacttccccc
     2221 agcctccgcg cagcacccag aaagtcattg agctggaaaa agtctgccaa tcctatggcg
     2281 accgcagggt ttatgaaaac ctggacctgc tggtagaacg cggggagcgc actgttcttg
     2341 taggcccgaa cggcgcgggc aaatccactc ttctcaaaat cctggcgggc atcatcccca
     2401 ttgactccgg acaacgcact cccggtacca cgacgcgcat cggctacttc tcccaggcgc
     2461 gaacggaaaa cctgaatccg gaaaataccg tgctggagga aatcatgaaa tgcagcgctg
     2521 aaatccggga ggaagaagcg cgttccatcc tgggttcctt cctgttccgg aggctggatg
     2581 tggaaaaacg cgtcagcgtt ctttccggcg gggaaaaatc gcggctcagc ctggtcaaat
     2641 tcctggtgga tccgcccaac ctcctgctga tggacgagcc gaccacccac ctggaccttt
     2701 tgtccgtaga agccctggtg caggctctga agcattatga aggaacactg gtcttcatct
     2761 cccacgatgt gcacttcatc cgttccctgg cacaaaaaac cctgcatgtg aaccggggga
     2821 ccatcaccgc ctacgcaggt ggatatgact actatctgga aaagtcaggc attctggacg
     2881 atgaaaaagg cggcatcacg gcggaataag gctctttttt cagtttcccc tttttccttg
     2941 ccgtggattt catcctgcct taaaagaaca ggatgaaggc ttttcttgtt cctctcttat
     3001 attctgcgct tctgtccgga gcctctcttg catttggtga aacggccgcc ggaacggctt
     3061 cccccgcagc agcggctccg gcggaaaaaa ttccttccgc ggaatccctg atcaaccagg
     3121 ccttttcctt tgccatcaat atccagcaga cgttggcagg cgttcaggac aaggaaagcg
     3181 tggacaacgc cgtcaaaacg ctgcaggaca ttcagaagga catccggcat ttcctccagc
     3241 ttcaggataa attgaacgat gcggaaaagg agaaagaaga cgccttgata gaaaaaatgg
     3301 aaaaacgaat ggaaatgctg gacaaccgct gcaggcagga aggcaaacgc ctgtttgagg
     3361 cccgctatta cggttccgcc gccttaaagg acattttgga aaattcggat gaattcagcg
     3421 acctggtaga accggatgaa gacggggcgc cccccggtgc actccgggaa aatgaagagg
     3481 ccggacagta gccccccgcc ccgtttctcc cccctctttt ttcattcccg gcacgcccct
     3541 tccccgtatg ggttcctgcg cggccaagtc catttcaagc ttgccggaac cgtgaaaaac
     3601 gggtttactg tgggcagcat gcaaaagtta gcaggtaaaa cagccatcgt taccggcgcg
     3661 ggccgcggaa tcggcaatgc cgtcgcgcgc cgcttcgctt cggaaggagc cagggtcatc
     3721 ctgatcagcc gcagtccatc cagctgcggg ggggccgcag aagaaatcaa caaggaattt
     3781 ccggattcct gcaaggccta cccctgcgac gtagcggatt acgcggccgt tcaggaaacc
     3841 atggccgcca ttttgaaaga cttcccgcag attgacatcc tggtgaacaa cgccggcatc
     3901 acgcgggact ccctgatgct ccgcatgaaa gaggaagact gggatgccgt tctggacacc
     3961 aacctgaaaa gcgcgttcaa tacggtcaag gccctccagc gcgttctcat gaaatccccg
     4021 gccgggcgca tcatcaacat gagctccgtc atcggtctcg tcggcaacat cggtcaggcc
     4081 aattacgccg cttccaaggc gggcctcatc ggtttcacca aatcactggc tcaggaattc
     4141 gctccgcgca aagtcacgtg caacgccatt gctcccggct tcatctccac ggaaatgtcc
     4201 aatgccattc ccgacaatct caaggaagaa atcgttaaga aaataccttt gaaagaacaa
     4261 ggttccgtgg aagatatcgc cgccctgacg gccttccttg cctctgacga tgcccgttac
     4321 atcaccgggc aggtcattgc ctgcgacgga ggcatgacga tgtagggcat tccggttttc
     4381 tccattccat gcgcggcatt ttccttgttt cctgctttct gggaggaagc gccctgctgg
     4441 ccgggtgccg ggaagaaaat aattcccccc gcccggccac ggaagatgcc gcgcgcatta
     4501 ccagcgcacg ccagtgggga gaaagccgat ccgcgctgca aaaacgggaa ctggaccgcg
     4561 ctgccggtcc tgcccttccc attccggatg acctgccgtc ccgggagctg gtcggcacaa
     4621 cgcgccaaat ccatcagctc attgaagctt ccggaaatcc ggcacgtttt gaatcctaca
     4681 cggaaacggt tcccgtggcg gaagcttccc tgcgcatggt cgccataccg ggaggaacgt
     4741 tcctcatggg gagtcccgcg gaagagccgc accggaaacc ggacgaaggt ccgcagcata
     4801 aagtgagcat ctcccccttc tggatctcgg aaacggaaat cccctgggaa ctttatacgg
     4861 ccttcatgga aaacgggcgt ccgcgcgcca aggacggcca gcttctggag gaacagccgg
     4921 atgacgaact gtgggactcc gttacgcagc ctaccgcccc ctacaccgcc atgaacctgg
     4981 gcatgggcca cggctatgaa cacggtctgc ccgccatctc catgtcccac cacgccgcca
     5041 gcaaattctg cgaatggctg agcgcccaga ccgggcatta ctaccgcctg cccacggagg
     5101 cggaatggga atacgcctgc cgggccggct cccccggcgc ctattcttac ggaaacgggg
     5161 aagcctctct ggaccagtac gcctggtact ggaacaactc caatgaccgc taccagaaaa
     5221 caggctctaa aaaaccaaat aagtggggac tccgggacat gcacggaaat gtggcggaat
     5281 gggttttgga ctcttacgtt ccggatgcct acggcaaacg gagcggcttg cccgcgaaag
     5341 accccttggt catcatcccc agcgcccctc acatcgttcg cggcggttcg tgggaagacg
     5401 acccggacag cctgagaagc gctgcgcgcc gcgccagcac ccccgcctgg aaccgtcagg
     5461 atcctcaaaa ccctaaaagc atctggtacc tgacggacgg aggcatgatc gggttccgcg
     5521 tggtgcgccc catgaacatt ccggacatta tgacgatgca ccgcctctgg aatttctcca
     5581 agggggagcc gtaaagaaca acctttcatg accattgcat taagaacgga acaatcctca
     5641 gaccatgccg aaacggaaca tgtcacgaga gaagcgttct ggaactattt cgtccccggc
     5701 tgccatgaac attacctgct ccatatcatg cgcgtcagtc cgtccttcat cccggagctg
     5761 gatgcagtcg ccgtccacgg cagccgcatc gtcgggaaac atcgttgatg caacgtccgt
     5821 catcagggca gacgatggaa aagaatatga agtgctgggc atggggccca ttgccgttct
     5881 tccgaaatac cagcgccggg gaataggacg gcgaataata tgtatgcggc ggccctccag
     5941 gtctgtgagc tgcaaagggg ttccctatcc ggcctgaaag gccactatgt gaaagctgcc
     6001 gtgtaccata tggacgaaaa gcgcgctgcc gaatttgacg gcatttcccg gtaaagaaaa
     6061 agctttccgg tactgcgtct caaaaacgtt tccagcaaat tgccgccatg ccgaaaaaac
     6121 cggatacggc cccctgcccc cggaaattcc gtaccttccg gagggcatga atcccgcata
     6181 cggataagca attcttcctc tctggatata aaaaacaaga gctgttccgc aagaacagct
     6241 ctcatccgcc gatttttcgc catcaggaag ctcaagccct gaggcggcgc atcatcagcg
     6301 cggccagtcc cagcaggccc agggaaaccg tggctggttc cggcaccatt tcccctcgga
     6361 tttccgtgaa aatcggggat aataagctga aagtattggt tccgttggct cccgtaataa
     6421 cgacagaatc accaggcgct ccctcggcgt cataatggcc gcggatgccg ggagcagtca
     6481 atccgccgct gatcgttacg gtatctcctt ccgtgttagc agtaggggcg gctgttcccc
     6541 ccgcagcata taaatacgtt ttagacgtat cctgcatcaa gtccatcacg gactggctca
     6601 cggccaggaa acggtatgtc aatgccgcgt caagaagcag gggagaacca tccagggaag
     6661 aaaaactgaa cgtcagatta atccctgctg cagtagttcc cgtattggtg ctccagccga
     6721 tgaccgaatt gtcggagcca ttcagcacca ggaagccgta agtgacatta gcgcccaaat
     6781 tgttggcggc tccgcgcagc gtaaaactgt ccagtctgat ctctccggac agggaggagg
     6841 gagaagagga atcggaagga gccagggaag aagaccccag gccaagataa aacccatgga
     6901 tggtactatt gtaattatcc gtaccgggag tgtaataatt aaaaacggtc gctgcctccg
     6961 aggaaacagc aaagcttccc atcgcgatta aaaatgtcag tgttttcttc atatttatta
     7021 ttccttttgg atggcaactt gtagcgaatt tggaattccc caatcggatt tggaatccgt
     7081 caagtaatga aaaagaggcc aaatcaatca tgaaaccaat gaataacaaa gattgccccg
     7141 tcatcttgac aaaaggacca gagatattaa aaaatcatta ttttcaatga attataaata
     7201 caatatacta actcttaata tttttaattg cttgcggatt ccaaattcgt tattcaagcg
     7261 caagtgcata cattgaatct tgcatcattt tattaagata ctgaccatga agaaattatt
     7321 atccaccctg attctttcgg ccggcatgag cctgagcgcc accgcgaata ccactctgct
     7381 ggatagctct atcgtgggat attcggactt tacctcccaa acggcggatt tcggcaccct
     7441 gaaagattcc gtttccatca cgtctgacga cagcaatctg acgttatccg ggataacctt
     7501 caacggatac ggtaccaaca accgcgacgt tatgtctgtg acaatggttc ttgatctgtc
     7561 caaaatcaac actccggaga cctataccgc tctgtttaac gccaaaaaca gcagtgtaag
     7621 ctggggcgtg ggcctgaaca cggaccggaa actccaggga ttatggaaca acacctcata
     7681 cagcgggccc gtcgttgaca ccccgctggg catggaaggg tccctgacca tttccgtagt
     7741 caccggagat cttggcaccc gcatctattt tggcgacagc gctacgtact attccaacag
     7801 cggcctgaaa ttcggcaacc agcaaattga tcagattctc atggacgcag gactggctga
     7861 atccatcgaa cagctctaca tccacgactc cctcctttcc caggaacaag ttggtcaact
     7921 gatgagtgaa atcgccagca ttccggaacc cgccacggct tccctgggcc tgctgggact
     7981 ggccgcgctg atgatgcgcc gccgcagggc ataagcctgt accgtccgcc tccctatatt
     8041 caaaggccgg ctcacaaaat cgtgagccgg ccttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatagca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 actggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctac gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagtggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgttgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgct tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactccc
//
