LOCUS       c00038_gnlPro..        16149 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDOMKIPJ_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:05:44
            Original ID  :: gnl|Prokka|LDOMKIPJ_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1788
            Orig. end    :: 17937
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16149
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11788:14852]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13064
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16149
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16149
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(923..2083)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 34.3; E-value: 4e-11)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_3"
                     /sec_met_domain="MFS_1 (E-value: 9.8e-12, bitscore: 34.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVPLPKTTQGVYRLSVSTFYFLQGLVFASWASRIPDIKSALGLN
                     DADLGSVLFAVPVGQMSAMALSGYLVGRCGSRKILMAASVFYPAVLVCLGMAGSFWELA
                     AGLFFFGVAANLTNISVNTQGVGVERLYQCSIMARFHGLWSLAGFFGALLGAAMVDWHI
                     SAETHFIAIFLICMIILAVFSPSLLPRDARRSSSQGGGMFRSMDAYVLVIGLIAFGSMV
                     SEGTMFDWSGVYFESVVKPGPGLVQMGYVAFMSTMALGRFTADRLVMRFGPVRVLRASG
                     ILIASGLLVSVLFPMLWSATLGFLLVGFGTSSIVPLCYSMAGKSRKMIPSMALASVSTI
                     GFLGFLMGPPVIGHIAHASSLRWSFSLIALVGLGTAFIAPFLKKYR"
     CDS             complement(2305..2685)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_q4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="Oxidored_q4 (E-value: 7.7e-34, bitscore:
                     105.9, seeds: 391, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQEFFSVLVQVAAALGLAGMILLLSILMGKRSSVRKPADIPYEC
                     GMIPMGEGAPMFSVKFYMVAMLFVIFDLEVVFLYPWAVNFRDYIMMNPESFTAMCIFIG
                     ILLVAYLYALGKGALNWHHDPR"
     CDS             complement(3085..3267)
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MLLSDFFNMLAMAVFACIGGVFLGMGFLLLKLAGIFFGILAGCII
                     LMEAAGRWISHLMGA"
     CDS             complement(3303..4202)
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MLSEAVLALEVRINDDSGSVMDSVKLIASDMDGTLLNGKGELDPA
                     FFPLFRELELRGIRFAAASGRQYDGLLRTFAPVGDRMLFIAENGAYAAAGRKEWLLLDM
                     DHETVAGLIAGIRCIEGTCIVLAGRDSAYIEDKQPEFVREARKYYTRCQEVGDLLDVRG
                     DKLLKIAVYDFLGAGENSYPRLKHLEHGFQVAVSGEKWMDISRKGANKGVALELIQRKL
                     GISSEETMVFGDQMNDASMIRQARFSYAMANAVPEIRSMAAFEAPSNEENGVMQVLGNM
                     LDAHSPQGRAGNCRKPRL"
     CDS             4680..6041
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MIHMTLRKKTLWFLGALSFFASLAATFAVFWLNRNDSSPAEWNFN
                     PIWTKAEKEQILTAANFTAHRSPERFIYRGLSLNSRHIDWHMFSEVSMRQYMKDEIRER
                     LQMIRDTAESADGRCITPSHETLLHLAAGLGEVQLLNRLLQRHADPNVQIILPQQAFPS
                     IPDSEQGNTPLTYACQPGMDDSTPLPVHNRISCLNLLIQYGADVNKPGPLGWPPLVITC
                     VAGIGGAPYEEAALFLLKCGADISLQPELKGKKTSLLTWAAAAGYPLLVRKLCEAGYDP
                     NFRGEMAPPLLSLNLNTPNAALQIAHILLEYGADVNAAMPASTTLPETAGDTALLNLCR
                     QLAFIGVSSLPQIRDLVNLFIKEGADVNHQNAAGETPLMACCRGMLLGDDSLDRLKLGI
                     ARLLLDHHANPSLKDKYGRTALQRIGNRSNEHLQMVLKYLPELSAPPLLKKENH"
     CDS             complement(6055..7842)
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MKNLLFALLTGSFCCCYAQQKAAPVPEPEVVATPPADAGRGLIRV
                     DSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTREF
                     IRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKSLKKLGGIMRTPVFVNKG
                     RRVIVPFHNMGGGTKFHISDDGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVL
                     EMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGTLTMNTLGRLDDGTIVSLW
                     TNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATL
                     DGPEDRGKHQSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQW
                     TIHTYIPHKKGHCSYNRKPSAELIQDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGA
                     TWNFPNGTTGLVKFRFRVADGEQADDSGLQVSLTDRLFNACDSTTKDYALFTFPIRLRP
                     APHLLLGMKKVPFSPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGVSYIHFIS
                     TGSQPDAGILLDTVNARVK"
     CDS             complement(7927..8715)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_9"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 9.8e-24, bitscore:
                     74.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSYILAILLGSSSLAFSAPSIPASALPVTLKPEPHQRDPYDW
                     NARHEAVKKRNRAVKPEYVMIGDSITHHWGGEPSGDGKNTGSGSWEKLFGPHAATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAELHNGKDIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             complement(8938..9720)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 7.4e-24, bitscore:
                     75.1, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYACLCLLLAGVFCVACFSGACADELPPTLKPQVNPRAVYDWK
                     KRHEAVMERNRTVKPEYVVFGDSITHRWGGEPSGDNRALGTGKTAWDSLFSSHAVTNMG
                     FGSDYVDNAYYRLQLGELDGISPRVIIVLLGTNNLGGRKDAPRVCADNLKAFVSLARRK
                     CPSSKILLLGILPREEKKLAPLIRETNKMISGLADGNSVFFANPGEEFLGEDGVSPKPG
                     LLEDGLHPSARGYDILGKSLSVLLKKMDDKYGKLPAPR"
     CDS             10001..12268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_11"
                     /sec_met_domain="Gly_radical (E-value: 6.7e-46, bitscore:
                     145.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.7e-281, bitscore:
                     924.1, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISIVKDLKESTALPQEWQGFKPGAWTESIDVRDFIQHNYTPYSG
                     NEEFLSGPSQRTLRLWDELKVLLKREIDNGGVLDADEEVVSSITSHKPGYIDKELEVVV
                     GLQTDAPLKRALMPFGGLRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDI
                     RAARSAGIITGLPDAYGRGRIIGDYRRVALYGTDKLIAERRKDLKNREHSPLTDELIRL
                     REEMSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGR
                     VSTFFDIYFTRDLEQRLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTES
                     IGGMGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPEAFKSFCAKVSIETSS
                     VQYENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGK
                     QVAPPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHD
                     PEILRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVD
                     DIACSLVSNFMEKLRRLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGA
                     NPMHGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAY
                     FAATGHHINVNVLERETLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFH
                     TR"
     CDS             12285..13064
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 53.6;
                     E-value: 9.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_12"
                     /sec_met_domain="Radical_SAM (E-value: 1e-31, bitscore:
                     100.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQVFPQNHNPDGESSVTGLVHSVESCGTVDGPGIRFVLFLSGCS
                     LRCRYCHNPDTSYVRRGRLRSADDVLKEIARYRDFLQAAGGGVTLSGGDPLFQPDFAGA
                     VLKGCRKLGLHTCLDTSGHLGVNAGEEMLADTDLVLLDIKAWNPKRYRALTGGELRPTL
                     EFAERLASLRKPVWLRYVLVPGVTDNLEEIEELSRHAALLGNVERVDVLPFHQLGRFKW
                     DELKLDYTLKDVPEASAELAEQVRGIFRRGGFPDCVH"
     CDS             complement(13313..15238)
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     SAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSRSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEAL
                     ATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALVADEFYN
                     DGPLDLGVMLDGDMETLKALEPYGPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQ
                     LYLQLGVLHGLDVATPSLFPVKKAAPAEDAPILIAPFSRLGSASEWSREQWRELVSLLP
                     GRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDFPSLCSFRG
                     LPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVRDVLEALR
                     EISEKE"
     CDS             15388..15690
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MLYCIFLIKASLRRRHLTFGKEMTLQFLTNRYIPSPEPNTKPELY
                     TMKVLSSLASMKRRHADCQIVKRKGTLYVICKSNPKFKARQGATAGTRLSKKGVK"
     CDS             15777..16148
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="MQLPAVQTKFLDLPNSFSLRNGATLDKVRVAYEQYGTLTPNKDNA
                     ILLFHALSGSQHAYGYNPEVPGIGSLWKPENHEGWWNSIIGPGKPLDTNRFCIICANYL
                     GGCYGTTGPATPCPADGQPS"
ORIGIN
        1 gtggcgttgc tgagcggttg ttttcgatat cggaatgaag ccagcttttc ttcgatcatg
       61 tccggtgtaa tctgattaag cggaaggtct tcccatccct gtgcccattt ttgcagttcc
      121 atgaccatgc tgtcatgatg ggctttcttg accagatttg attcaagttt tttgtcgata
      181 acctctcgat attgttctgc aagaagacca aactttcttt taaaatcgac cttaacctgt
      241 tctgttttat tggcaaggaa tctggtcaga gaaaacaaat ttgtcagttc ctccagtcga
      301 tccagatttt cctggtccgt tcgcgttaca atccagttac catcagcgtc tttccggcca
      361 taacttgcac cgttggctat ttcctgcttc aggtttttca aggcttcccg tactaccaaa
      421 tacaaaggaa gggaggattg ttgggtcact tcatcataga tgttcctaaa ttcccgccat
      481 aaaagaatgg cattgtaatc atgttcatca acatgttccc tccactcctg ctttcgcaag
      541 tattccggca acatatcctc caaggactga tgcagaagcc gttgataggc ttctcatgcc
      601 ttttcatagg tatcaaagag ccgatgaata tgcggacgta ccgacatatt gcgcaccagc
      661 cattttttct ttccccggtg cattctacag gtaagagaga tatgtgaacc ataatgtttt
      721 ttccgggatc tcctcacggt tgaaagtatc ccatagctca ttttcattga caaaccgaaa
      781 gtgtgtacaa actgtgtaca gaaacttaac taattgataa ttaaaatact gattcagact
      841 taggatctgg tgccgaaagg cgtacaggtt cgagtcctgc caggcgcacc atttcacaat
      901 ataggcatat cattaacagt gattacctat atttcttgag gaaaggggca atgaatgccg
      961 tccccagtcc aaccagggca atcagggaga aagaccaccg gagggaggaa gcatgggcaa
     1021 tatgaccaat gaccggcggc cccatcagga accccagaaa gccgatggta gaaacggaag
     1081 ccagcgccat gctgggaatc attttccggg atttcccggc catgctgtag cagagcggga
     1141 caatggaaga ggtgccaaaa cccaccagca gaaagcccag cgtggcggac cacagcatcg
     1201 ggaacaggac ggagacgagc aatccggagg caataaggat gccgctggcg cgcagaaccc
     1261 gcacaggccc gaagcgcatc accaggcggt ctgccgtaaa acgccccagg gccatggtgc
     1321 tcatgaatgc cacgtatccc atctgcacca gccccgggcc gggttttacc acgctttcaa
     1381 agtacacgcc gctccagtca aacatggttc cttcgctcac catgcttccg aaggcgatca
     1441 gcccgatgac cagtacataa gcatccatgc tccggaacat gccgcctccc tgggaggagg
     1501 aacgccgggc atccctcggc agaagagagg gggaaaaaac ggccagaata atcatgcata
     1561 tcaggaaaat ggcgatgaaa tgcgtttccg cagaaatatg ccagtccacc atggcagctc
     1621 ccagcaaagc tccgaaaaaa cccgccaggc tccataaacc gtggaaccgg gccatgatgc
     1681 tgcactggta cagccgttcc actcccactc cctgcgtatt gacggatata ttcgtcagat
     1741 ttgcggctac cccaaagaaa aataacccgg ccgccagttc ccagaaagac cccgccatac
     1801 ccaggcatac aagcacggca ggataaaaga cggatgccgc catcagtatt ttccggctgc
     1861 cgcaacggcc aaccaggtaa ccggatagcg ccatggcgga catctgcccc accgggacgg
     1921 caaagagaac ggaccccaag tcggcatcgt tcaaccccag tgcacttttg atgtccggga
     1981 tgcgggatgc ccaactggca aacaccaaac cctgaagaaa ataaaaggta ctgaccgaca
     2041 gacggtaaac accttgcgtc gttttaggaa gaggcacatt catgatgaat ttcctgatcg
     2101 cgcaaacgct atccctattc ccctcttctg gcaagagaaa tcatcttttg tacaataaga
     2161 ttttacacgc aaacaggcat ccggaaaaag gacaggattt acggatattt ctcccccgcc
     2221 attttccaag gcaatttttc tttcacagaa aaaacgccgt attccttcat ggaacacggc
     2281 gttggtaaaa gggaacaaaa acggtcaacg gggatcgtgg tgccagttca gggcaccctt
     2341 gcccagcgca tacaggtagg ccaccagcaa aatgccaatg aaaatgcaca tggccgtgaa
     2401 cgattccgga ttcatcataa tatagtcccg gaaattgacg gcccaggggt agaggaatac
     2461 cacttccaag tcaaaaatga caaagagcat ggccaccata tagaatttta cagagaacat
     2521 gggggcgcct tcccccatgg gaatcatccc gcattcgtag ggaatgtccg ccggtttacg
     2581 cacggaagaa cgcttgccca tcaagatact gagcaacaag atcatgccgg ccagccccaa
     2641 ggcggccgcc acctgcacga gcactgaaaa aaattcctga ttcatgacgt ctggcacggg
     2701 tgtaccacag acattgcgga aaagcaaaac taaaaaggac aacagctttc atgctgacgg
     2761 gagggacggt aaaattccgt ctcccgccct gtcaaacagt acaaaggcaa cagtcccttc
     2821 catggggacg cccggcattt catatccctg ggacttcctt tctgcggggc tctgtcttcc
     2881 agggcatctt acggcaaacg tctgtttatc acaaaactcc gctatccggt tttaacacgc
     2941 agaatccagg caggatgcag ccttccactt cagcattcgg caatgaaccg gcaacaacag
     3001 cagccggcaa tggcccagcc atcagaaagc tctcccctca cggaaagcgt acaggaatcc
     3061 ccttcattgc cgggaataac ggactcacgc ccccatcaaa tgggaaatcc accttccggc
     3121 cgcttccatc agaataatac accccgccaa tattccgaaa aaaattcccg ccaatttaag
     3181 cagcagaaag cccattccca gaaaaacacc gccaatgcaa gcgaacacgg ccatcgccag
     3241 catattaaaa aaatctgaca ataacatcaa cataaccctg attttattcc attacccggc
     3301 aattagagac ggggtttcct gcaattcccg gcccttccct gcggagaatg ggcgtccaac
     3361 atatttccaa gcacctgcat cactccgttt tcctcattgg acggcgcctc aaatgcggcc
     3421 atggaacgga tttccggcac ggcattcgcc atggcataac tgaaacgcgc ctgccgtatc
     3481 attgaagcgt cattcatctg atccccgaaa accatcgttt cctccgaaga aattcccagt
     3541 ttcctctgaa tcaattccag agcgaccccc ttattggccc ctttccggct gatatccatc
     3601 catttctctc cggagacagc cacctggaag ccatgttcca aatgcttcag ccggggataa
     3661 ctgttttccc cggctcccag gaagtcatat actgctattt tcaaaagttt gtctccccgc
     3721 acgtccagca ggtctcccac ttcttgacag cgtgtgtaat atttgcgggc ctcccggacg
     3781 aattccggct gtttgtcctc aatatatgcg gaatcccgcc ctgcgaggac gatgcaggtt
     3841 ccttcaatgc acctgatccc ggcaatcaaa ccggctaccg tttcatgatc catgtccaga
     3901 agcagccatt cttttctacc cgccgccgca taagcgccat tctcggcaat aaacagcatc
     3961 cggtccccca cgggggcaaa ggtccggagc aatccgtcat actggcggcc gcttgctgcc
     4021 gcaaaacgaa tgccgcgaag ctcaagttcc ctaaacaagg gaaaaaacgc agggtccaat
     4081 tcaccttttc cattaagcag cgtcccatcc atatcggacg caataagttt gacggaatcc
     4141 ataacgctgc cagaatcatc gtttatcctt acttccaggg caagaacggc ttcagacagc
     4201 atggagcgga cagcgaaagg aaagaccagg aggccagcag caaggataca gttctctcca
     4261 tcattttacg ggagaatctc catttcttcc ataagtttca gctttcttca ttctaccgtg
     4321 agtgcagcag cggcaaatgc aaataatttg aaaccatccg cacatccgca atatttagcg
     4381 tatcacaccg aattgcaaat tcggatacaa ttcaaataat tggagttaaa tgatccacgc
     4441 cataaactcc ataatttttg tgaagtccgg cccatgacac catattttcc gtttccttcg
     4501 taattctctt tatccacgag cttttttccc agatgaagag gaaaaaattc tcctccgaat
     4561 ttgcaatccg ccacccgaat tcccacatgg tttgccccgg gcattctttg ctcatactat
     4621 tttttcattg cccggagtta tggattcctg catcatggcc tttcgcagta cccctgctta
     4681 tgatacacat gactttaaga aagaaaactc tctggtttct tggagctttg agcttttttg
     4741 cctctcttgc cgcgactttc gccgttttct ggctgaacag gaatgattct tctcccgcgg
     4801 aatggaattt caaccctatc tggacaaaag cggaaaaaga acaaattctt accgcagcga
     4861 atttcacagc ccatcgaagc ccggaacgtt tcatttaccg cgggctttcc ctcaattcac
     4921 gccatattga ctggcacatg ttttccgaag tttccatgcg ccaatatatg aaggacgaaa
     4981 tcagggaacg gcttcagatg atacgggaca cggcggaaag cgcagacgga cgctgcatca
     5041 ctccatccca tgaaaccctg ctgcatcttg ccgccgggct cggagaagtg cagttgctga
     5101 accgcctttt acagcgccat gcggacccga acgtccagat catcctgccg caacaggcct
     5161 ttccctccat tccggactcc gaacagggaa atacccccct gacttacgcc tgccagccag
     5221 gcatggacga ctccacgccc ctgccggtgc ataacaggat ctcctgcctt aatctcctga
     5281 ttcaatacgg tgcggatgtg aataaaccgg ggccgctggg ctggccgccc ctcgtcatca
     5341 cctgtgtggc cggtattgga ggagcaccct atgaggaagc agccctgttt cttctgaaat
     5401 gcggtgcgga tatttccctc cagcctgaat tgaaaggtaa aaaaacaagt ctgctcacat
     5461 gggccgcggc cgccggatac cccctgctgg tccgcaagct ttgcgaagcc gggtacgatc
     5521 ccaatttccg cggggaaatg gccccgcccc ttctttccct gaacctgaac actccgaacg
     5581 ccgcactgca aattgcacat attctgctgg aatacggagc ggatgtgaat gcggccatgc
     5641 ccgcgtccac caccctgccg gaaaccgcgg gagacacggc cctgctgaac ctgtgccgcc
     5701 agctggcttt cattggtgtg tccagcctcc ctcaaatcag ggatctggtc aatctcttca
     5761 tcaaagaggg agctgacgtc aaccatcaaa acgccgccgg agaaactccc ctcatggcat
     5821 gctgccgagg catgctgctg ggagacgatt ccctggaccg gctgaaactg ggtattgcgc
     5881 gtcttctgct ggaccaccac gcaaacccat ccctgaaaga caaatacgga cgcacagccc
     5941 tccagaggat aggcaaccgg tcaaacgaac atctccagat ggtgctgaaa tacctgccgg
     6001 aattaagcgc tccaccgctt ctgaagaagg aaaaccattg aatcccgccg atccttactt
     6061 cacccgggca ttcaccgtat ccagcagaat gccggcatcc ggttgggacc cggtgctgat
     6121 gaaatggata taactgactc cattagggga cttattagcc attttcaacg ttccggcctt
     6181 ctttccgtcc agagacacca cggcctgccc accctgccaa agaagggaaa tttcatgcca
     6241 cgcgccgggc gagaaaggca cttttttcat ccccagcaac agatggggcg caggtctcag
     6301 cctgatcggg aaggtaaaca gggcataatc cttcgtagtg gaatcacagg cattgaacag
     6361 ccggtccgtc agagagacct gaaggccgga atcatccgcc tgctccccgt ccgctacacg
     6421 gaagcggaat ttgaccaacc ccgtggtccc gttcggaaag ttccaggtag ctccgccgtt
     6481 ccggtaatcc acattggatt tttcattgac cagttcggga tcatccagac gcttgatttg
     6541 caacaccttc ttcgtgcccc cggacggatc ctgaatcagc tcggcggaag gcttacggtt
     6601 ataactgcaa tggccttttt tgtgggggat ataagtgtga atggtccact gggaatccaa
     6661 atctttcccc gtctgcgtgg cacgcgtctt ggcccctacc cagcggcggt ccacaataac
     6721 caggcggcgg tggtttttat gctgccccag ggaaataagg atgcggtttt tgtccagctg
     6781 caccatttcg ctctggtgtt tgccgcggtc ttccggacca tccagcgtag catagccggg
     6841 atggttgcgg tgttcgtcca ggataatctc ccggaacccg taccaggttt tgccctcgtc
     6901 cccggacata gcaatgtggt gggaatcacg gttggtgaat acatcctccc acgttccgtt
     6961 gccagctgtg gcgttttcag gcagagccat tgtattcgtc cacagggaaa cgatagttcc
     7021 gtcatccagg cgtcccaacg tgttcatggt cagggtgccg aaaaagcggg aaggctccgg
     7081 tttgctccac gtttccccgt aatccttgga aaaagcctgc cacgcctggt cctgggaggt
     7141 gcgggcaagc gcccacaacg taccgtcttt catttccaaa accgtggctt ccacggcatt
     7201 gttgaaccat ctgacgccct ggtggggggg cctggcttca tgtctggggg aagtaacacc
     7261 gttcctggat acatgccagg tcagcccccc gtcatcggaa atatggaact tggtgccgcc
     7321 gcccatgttg tggaacggca cgatcaccct gcggcccttg ttcacaaaaa cgggggtccg
     7381 catgatgccg cccagttttt tcaggctttt cctcttttcc gggtctttcc agtcttcttc
     7441 cagtttgccg tcattcgtga cggcaagcca cttgccgtcc agcccacccc tggaaagaaa
     7501 tacaaagccc ccgataggct gcacacgaat gaattccctg gtcaaagggt tgcgcacaat
     7561 agccggagat tccttgggaa tgccaccgta gttgggaggg tagccagccg gagcggcctt
     7621 catttcccat gtttttccgt tatccctgct gaccagataa tccggttcct tgcgggtacc
     7681 ggaataatgg cgtatttcac gggagtccac acggataagg ccgcgccccg catcagccgg
     7741 cggagtggcg acaacttcag gctccggaac gggtgcggcc ttctgttggg cataacaaca
     7801 acaaaaggaa ccggtcaaca atgcaaacaa caggtttttc ataaactaaa tatcaaaggc
     7861 cgtatatttt cctcaaccgg ggctttccct tcaagcaaaa tcctaccttc catcagaaaa
     7921 cgatcatcag gaatgctttc ccgcctgctt ccctccccgg tattttgcat caagcttttt
     7981 caggagtacg gccagttcct tttccaaaac ctcgtacccc ctggcattgg gatgcaccac
     8041 atccttcatg aattcattct gcggagaagc accatctgcg gaaagaagcg cctttcccgg
     8101 atcggcaaag aaaatgtcct ttccgttatg cagttccgcc aacagtctgt tcgtctgctt
     8161 caccggttcc gccaggtttt tctccttccg tgggagaacg cccagcaaca ggattttgga
     8221 agaggggcac ttccggcgca ccaggcggac aaatgccctg atattgtccg cacatgcctg
     8281 cggcgtatcc ttgcggtgcc ccagattatt ggtccccagc aacacaatga tgacccgcgg
     8341 agaaatgccg tccagctccc cgttttggac acggtaatag gcattatcca cataatcaaa
     8401 tccaaagccc atattcgtcg ctgcatgcgg accgaataat ttctcccagg aacccgatcc
     8461 cgtatttttt ccgtccccgg aaggctcccc tccccaatgg tgggtaatgc tgtcccctat
     8521 catcacgtat tcaggcttga cggcccggtt tcttttttta acggcttcat gccgggcatt
     8581 ccaatcatac gggtcccgct gatggggctc cggcttcagg gtaacgggca acgcggaggc
     8641 cggaatggaa ggcgcagaaa atgccagact ggaactcccc agcaatatgg cgagtatgta
     8701 ggagaggaaa ttcataatca aaaagtaaaa ccggttttca gtttaagcaa atcctgccgt
     8761 gcatcaagat cgcaggcgtc acttccgccg gcagagtaaa aaagaccact gcccgtccgg
     8821 caaatcctgc cgcagccacg gccaggcgag caccgtgttc ggcctcttcc aaggcgcgct
     8881 ccatttcatc catcccccgg cctctcccgg aacaggaacg ccctcccccg tattcatcta
     8941 ccggggagcg ggcagcttgc cgtacttgtc gtccattttc ttcagcaata cgctcaacga
     9001 cttccccagt atgtcgtacc ccctggcact gggatgcagc ccatcctcca gtagcccggg
     9061 ttttggggac actccgtcct cccctaggaa ttcctcgccg ggattggcga aaaacacgct
     9121 gtttccgtca gccaggccgg atatcatttt attggtttcc ctaatcaggg gagccagctt
     9181 tttttcctcc ctggggagaa tgcccagcaa caggattttg gaagaggggc acttccggcg
     9241 cgccaggctc acaaaagcct tgagattgtc tgcgcagacc cggggagcat ccttccgccc
     9301 gccaagatta ttggttccca gcagcacgat gatgacccgc ggagaaatgc cgtccagctc
     9361 tcccagctgc aagcggtaat aggcattatc cacgtaatcg gaaccaaacc ccatattggt
     9421 taccgcatgg gaagaaaaca ggctatccca ggcggttttt cctgttccga gagccctgtt
     9481 atccccggaa ggctcgccgc cccagcggtg ggtaatgctg tcaccaaaga cgacatattc
     9541 cggtttgacg gtccggttcc gctccatcac tgcttcatga cgttttttcc agtcatacac
     9601 ggcccgcggg ttcacctggg gcttcagcgt gggcggcaat tcatcagcac aggccccgga
     9661 gaaacaagca acgcaaaaaa ctcccgccag caataaacaa aggcatgcat aagatttcat
     9721 aacggtaagc gttgagatac tgcaatagag attaggaaag taaagagaaa taatcttccg
     9781 tcacttttcc gcaatcgcat gttcccctca ttttccgctc cgcaacggac agacaggtga
     9841 aacatgccaa agccagcgca cccgcgttct cttcgcaaag aattagcctt gttgtccccc
     9901 ggaattcacg atataattac gcggcgcgga gttttgccgt ttccagcctt tcaggggctg
     9961 cggaacgttt ttctccagtc ttcttcacta cattctattt atgatcagca tagtaaaaga
    10021 cttgaaggag tccaccgccc ttccgcagga atggcaggga ttcaagccgg gagcatggac
    10081 ggagtccatt gacgtacggg atttcatcca gcataactac acgccctatt ccggcaatga
    10141 agagtttctt tccggcccct cccagcgcac gcttcgttta tgggacgagc tgaaagtcct
    10201 gctgaaacgg gaaatagaca acggcggcgt gctggatgct gatgaagaag tggtatcctc
    10261 catcacatcc cacaagcccg gctacattga caaggaactg gaagtggtcg taggcctcca
    10321 gacggacgcc cccctgaaac gggccctgat gccctttggc ggcttgcgca tggcccaaca
    10381 ggccctggaa tcctacgggt tcaagatgtg cgagaaaacc gcagacattt tcaaaaagat
    10441 acgcaagacg cacaatgaag gcgttttcga cgcctacact tccgatatcc gggcggcccg
    10501 ttccgccggg attattaccg gccttccgga cgcctatggc cgcggccgca tcatcgggga
    10561 ctaccgccgg gtggccctgt acggcacgga taagctgatt gccgaacgcc gcaaggacct
    10621 caaaaaccgt gaacattccc cccttacgga tgagctgatc cgtctgcgcg aagaaatgag
    10681 cgaacaaata cgcgccctgg aagaactcgc ccagctgggc gcctcctacg gctgcgacct
    10741 cactcgcccc gccgcaaacg cccgcgaagc cgtgcaatgg acgtacctgg gctacctggc
    10801 cgccgtgaag gaacagaacg gagcggccat gtccctgggc cgcgtttcca ctttcttcga
    10861 catttatttc acccgcgacc tggaacagag gctcatcacg gaagaggaag ttcaggaaat
    10921 catcgaccag ttcgtgatga agctgcgcat cgtccgtttc atccgcacgc ctgattacaa
    10981 taacctgttc tccggagacc ccacctgggt gacggaatcc atcggcggca tgggagagga
    11041 cgggcgcacc ctcgtcaccc gcagttcctt ccgcatgctg cagaccctgt acaacctggg
    11101 gccggctccg gaaccgaacc tgaccgttct gtggtcccgg aacctgccgg aagccttcaa
    11161 aagcttctgc gccaaggttt ccattgaaac gtcctccgtc caatacgaga acgacgacct
    11221 gatgcgcccg cattggggcg acgactacgg catcgcatgc tgcgtgtccg ccatgcgcat
    11281 cggcaagcag atgcagttct tcggagcgcg cgccaacctc gccaagtgcc ttctctacgc
    11341 cctgaacggc ggcgtggatg aactcaaggg caagcaggtg gccccgccct ccccccgcta
    11401 cacggaggaa attctcaact atgatgaagt gatggccctg tacgacaaga tgcaggactg
    11461 gctcgccaaa acttacattg acgcgctgaa catcatccat tacatgcacg acaaatactg
    11521 ctatgaacgc attgaaatgg cgctgcatga tccggaaatt ctgcgcacga tggctacggg
    11581 aatcgccggg ctttccgtgg cggcggactc cctgtccgcc atcaagtatg ccaccgtaaa
    11641 agccatccgc aatgaggaag ggctgattgt ggacttcaaa acggaagggg aattcccctg
    11701 ttacgggaac aatgacccgc gcgtggacga catagcatgc agcctggtca gcaatttcat
    11761 ggaaaaactg cgcaggctcc acacttaccg caattccctg cccacccagt ccatcctgac
    11821 gatcacctcc aacgtggtgt acggcaaaaa gacgggcaac acgccggacg gccgccgagc
    11881 cggggaaccg ttcgcccccg gagccaaccc catgcacgga agggacagga acggagccgt
    11941 ggcctccatg ctctccgtag ccaagctgtc ctatgacgac tccctggacg gcatctccta
    12001 caccttctcc atcgttcctc aggccctggg caaggaggaa cgtgaacgcc gcgtcaagct
    12061 cgtctccctg ctggacgcct actttgccgc tacaggtcac cacattaatg tgaacgtact
    12121 ggaacgggaa acgcttctcg acgccatgga tcacccggaa aaatacccgc agcttaccat
    12181 ccgcgtttcc ggctatgccg tgaatttcat caagctgacc cgggaacagc agcaggaggt
    12241 catcaaccgc actttccaca cccgttaacc cggactgcaa gcggatgccg caggtttttc
    12301 cacaaaacca taatccggac ggagaaagct ccgtcaccgg tttggttcat tccgtggaat
    12361 cctgcggcac cgtggacggc cccggcatcc gcttcgtcct tttcctgtcc ggctgcagcc
    12421 tgcgctgccg ctactgccat aatccggata cctcctacgt gcggaggggc cggctcagga
    12481 gcgcagatga tgtcctcaag gaaatagccc gttaccggga ttttttgcag gcggcgggcg
    12541 gcggagtcac cctctccggc ggggatcccc tcttccagcc ggattttgcc ggtgccgtgc
    12601 tgaaaggctg ccggaaactg ggcctgcaca cctgcctgga cacctccggc catctgggcg
    12661 tgaatgcggg cgaagaaatg ctggcggata cggacctggt cctgctggat atcaaggcat
    12721 ggaatccgaa acggtatcgc gccctgacag gcggggaact gcgccccaca ctggagtttg
    12781 cggaacgcct ggcctccctc cgcaagcccg tgtggcttag gtatgtgctg gtacctggcg
    12841 ttacggacaa tctggaagaa attgaggaac tctcccgcca tgcggcgctt ctgggcaacg
    12901 tggaacgcgt ggacgtgctc cctttccacc agctggggag attcaaatgg gatgaattga
    12961 agctggacta taccttgaag gacgtcccgg aagcgtccgc agaactggca gaacaggtcc
    13021 gcggcatttt ccggcgggga ggctttccgg attgcgtgca ttaaccggat tttcgcgctt
    13081 tggcgccacc aaccgcagca aaccggacgc aggcatcccc ctcttccgga tgaggggccc
    13141 tctcccctcc actgcagaat ccatgcaaaa aggaagacgc atttctggaa ttgctccgga
    13201 atacggcatt tccgcaattc ctttcgttat ttcatcattc tttacggcaa cggcagcatt
    13261 cccgccgttt tttccgccaa cgccggggga cggcattccg tcccttccca gattattctt
    13321 tctcggaaat ttcccgcaag gcttccagta cgtcccgcac ggcaatgtgg cggttgcagg
    13381 gaacatcccg gtcacattcc ttccggaagc agggagaaca gcactggtgg ctgtaaaggg
    13441 aacggttgaa tgtgcccata gggcggtaaa catccggaag ccgggtggaa aacagagtca
    13501 ccaccggaag cccccggaaa gaacagaggg acggaaagtc gccatccacg gctactgccg
    13561 ccgcagcgcc gtccatgacg ggaaagagag cctccggcgc acccaccgcc agctccacat
    13621 tcaaatgttc cgccagggag gcggcacgct cccggtcttc ttccagagcc gccagcaccg
    13681 tccgtcccgg cagaagggaa accagctccc tccactgctc cctgctccat tcactggcgc
    13741 tccccaggcg ggaaaacgga gcgattaaaa tgggggcgtc ttccgccggg gccgcttttt
    13801 tcacagggaa caaagacggg gtggcgacgt ccagcccatg cagcaccccc aattgcagat
    13861 aaagctgcac ccggtgcgcc gggggggcgg cgcgcaggac gggggccttt acccggaact
    13921 tgtacttccg ggcaccggga tgcgtgtcca gcccggaaaa catcatgggg ccatacggtt
    13981 ccagcgcttt cagggtttcc atatctccat ccagcatgac gcccagatcc agcggtccgt
    14041 cattgtaaaa ttcatctgct accaaagctt cccgaagctg cttcagggag tcgtgcggca
    14101 gcacatgggt aacttccggc accgtcttcc atatccccag ctgggcagac gggcagacga
    14161 tgttcacctg catgtcgcac cggacggttt tcaaagctcg aatcagggga acagtcgcca
    14221 gggcttcatc cagcgccctg ggaacggcta ccagaatgcg gtacggcttc agctccatat
    14281 tttccaggag cgcagccgtt tttttatcct gcggggcaaa tcggtcaacg gatttccagc
    14341 gatggtgcat ccagaacaca tccagcacgg attcccggat caatgtttcc agccccctgt
    14401 tcacttcaat cgtgtccccc gccagagagc cgtccgacct ggaaaaatcc accacattcc
    14461 ccatatccgc tatccagtgg ccgggagcat ccgtgcgcac cgctatggcc accatgtccg
    14521 cgccagccct ttttctcagc agagcgggca gcggagtcgt gccggtcacc ttgccgaaaa
    14581 aggggacata caccccctcc catacgaact ggtcgctcag cacgcccagg gctccccctt
    14641 ccttgagcat tttcatggga gccttgatgc ctccctcctt ggagaacatc tgagttccac
    14701 gttccgtgcg ccgctggtac acgtattcct ccatcagcgg attgtcaaac tggcggtaca
    14761 tggacccgta acgctccacc tccgggtaaa atgcgcgtat tctcgccagc gcctcccagt
    14821 tgccggagtg ggctatggcg caaacctgcc cgcgcccttc cagcacaggc gcggcaaact
    14881 gttcgtgccc tccgaccgtc acgcaatgct tcaactgctc atccgtcagg gtggccgtct
    14941 tcgcggaaca caaaaaattg gcaatggtcc ttttgaaatt ttcccggctt aatttctgca
    15001 gttcctttcc gcgcagggcc ggatccaaaa cgatgcgcag attcctttcc acaatgttcc
    15061 ggcgctgggg aagcagatgc cacgccacgg ccccagccgc gctccccagc cggtacagcg
    15121 ttttcatgcc cacgagcttc aacagccctt ccatgagcag aaaccctttc attcccaaat
    15181 gatgggcaaa cgtattccgg gaagccgggg aggaatcagg agaggaagaa tcagtcataa
    15241 ggaaaaccgg aaaagatgtt atacgaatcc cctccggtcc acaaaccctt tattcccccg
    15301 gcagagatcc cttcccgcat tttattttct cggataaatg acgtcttccc taaatttttc
    15361 cgccggcgcg gaatccaaag ccatcccatg ctttactgca tcttcctcat aaaagcatct
    15421 ctgcggagac ggcatcttac ttttggcaaa gaaatgactt tacaattctt aactaaccgg
    15481 tatattccgt ctcccgaacc gaacaccaaa ccggagttat acaccatgaa agttctttct
    15541 tccttagcct ctatgaagcg ccgccacgca gactgccaaa tcgtgaagcg caagggcacg
    15601 ctgtatgtga tctgcaagag caatcccaag ttcaaggccc gccagggcgc tacggcaggc
    15661 acgcgccttt ccaaaaaggg cgtcaagtaa tccctggccc agcacagatt tcaagaagac
    15721 cgccgcccgc cgggtgccgg tctttttttg ctgaccaagc ccctttccgt acatccatgc
    15781 agcttcctgc cgtccaaacc aaattcctgg atcttcccaa ctccttctcc ctgagaaatg
    15841 gagctacgct ggacaaggtt cgcgtcgcct acgaacagta cggaaccctg acgccgaata
    15901 aagacaacgc catcctgctg ttccatgctc tttccggcag ccagcacgcc tacggttaca
    15961 atccggaagt cccgggcatc ggttccctct ggaaaccgga aaaccacgag ggctggtgga
    16021 acagcatcat cggccccggc aaaccgctgg acacaaaccg cttctgcatc atctgcgcca
    16081 attacctggg aggctgctac ggcaccacag gccccgctac cccctgccct gcggacggcc
    16141 aaccctccg
//
