LOCUS       c00040_gnlPro..        14304 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LDOMKIPJ_40.
ACCESSION   c00040_gnlPro..
VERSION     c00040_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:05:44
            Original ID  :: gnl|Prokka|LDOMKIPJ_40
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14304
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14304
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[814:4304]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      815..4304
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14304
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14304
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..263)
                     /locus_tag="ctg40_1"
                     /transl_table=11
                     /translation="MNPPHRSSSAHRSAVPGYRKWYFGAGGSPGRRGMEAAPDPDPLPF
                     EAIRIHDERTVGPPSTSADGHSAHGYFTIPEGAEGKKLYGTC"
     CDS             complement(815..1582)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_2"
                     /sec_met_domain="Fer2_3 (E-value: 7.1e-24, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.4e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.4e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1623..3581)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.3e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.8e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3603..4304)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg40_4"
                     /sec_met_domain="SucD_FumR (E-value: 8.3e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4505..4777
                     /locus_tag="ctg40_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAVKAACGAPNLSK"
     CDS             4810..5595
                     /locus_tag="ctg40_6"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5629..5862)
                     /locus_tag="ctg40_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6292..6999)
                     /locus_tag="ctg40_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             7294..8034
                     /locus_tag="ctg40_9"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             8484..8669
                     /locus_tag="ctg40_10"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCIQLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(8713..9918)
                     /locus_tag="ctg40_11"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSAGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(9942..10871)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg40_12"
                     /sec_met_domain="adh_short_C2 (E-value: 1.6e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHALSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10816..11334)
                     /locus_tag="ctg40_13"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMKKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(11398..13008)
                     /locus_tag="ctg40_14"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAK"
     CDS             13131..13838
                     /locus_tag="ctg40_15"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
     CDS             complement(14048..14176)
                     /locus_tag="ctg40_16"
                     /transl_table=11
                     /translation="MKNIAILAIAGAACLVASCSQQQQQQQTTAPAPAPVVQAKGK"
ORIGIN
        1 gagcaggtgc cgtagagctt tttgccctcc gccccttccg gaatggtaaa gtaaccgtga
       61 gcactgtgcc cgtccgccga cgtactcgga gggcccacgg ttctttcgtc atggatccgg
      121 atcgcttcaa acggtagcgg atcgggatcc ggagctgcct ccatgccccg cctgccgggg
      181 ctgccgccgg ctccaaagta ccatttccgg tagccgggaa cggcagaacg atgggcggag
      241 gaggaacgat gagggggatt catcaggtat taaagagtcg ggggtaatga aggaagcgag
      301 gggtggccgc cctttcctga tcgttttatt aatagtatga tccgaagtcg gtgtcgatag
      361 aattttattt gtatgttttt gattttttat aaaagatggt cattatttta cacgaaaaga
      421 taatattata attcttacgt tcagtgcatt cccttaatag acatcaatgt tgtctgtttg
      481 ttagaaaatg ttttcctctc atgctgagcc cttgacagga ggccatccct tccgggcatc
      541 agtctaattc ctgtaatcaa tgtttttctt tctcgaagaa agatggggcc gtcgctgtcg
      601 gacggggcct gcttaggttt cgtccggcat ttccaagtac ggtctcctgg attactggaa
      661 cccttccggt gtaacaattt tttacgctgc gcgacgatga ggaagcaact gtctggtatt
      721 ttattcctgg ttcaaggaaa cctggtaatg aaaaaactcc cgacagccga tgccgccggg
      781 agtttttaca gagcgtctta agaaggaatc ttctttagaa acagaggcct tccttggcgt
      841 tggcccgcat gaagtcgcgg ttgaggcggg cgatgttgtc cacgctgatg cctttcgggc
      901 aggcggcttc acattcatac tggttcgtgc agttgccaaa gccttccgct tccatctgct
      961 tcatcatggc caggacgcgc ttggaacgtt ccggctggcc ctgcggcagc agattgagat
     1021 gggcgatctt ggcggaggtg aacagcatgg cggaggcgtt tttacaggag gccacgcagg
     1081 cgccgcagcc gatgcaggcg gccgcgtcaa aggcggcgtc cgccttcact ttttccacgg
     1141 cgatgttgtt ggcgttcggc gcggaaccgg tacgcacgtc aatatagcct ccagcggcga
     1201 tgatgcggtc cagggcggag cggtccacca tcaggtcccg caggattggg aaagccttcg
     1261 cgcggaaggg ttcaatccag acggtatcgc catccttgaa cttgcgcatg tgaagctggc
     1321 aagtggtcac ctggcgttcc ggcccgtggg gaatgccgtt gatggtcagg gagcacatgc
     1381 cgcagatgcc ttcccggcag tcgtggtcaa aatggatggg ttccttgcct tccttgacca
     1441 ggccttcatt gacgatgtcc agcatttcca ggaaggaggc gtccaccgga atgtccttgg
     1501 cggcataggt ctcaatgcgg cccttggctt cccggttttc ctggcgccag accttgagag
     1561 tgagattgag tgttttagcc atgttataat ctttcttttg agtgttaatg tattggctat
     1621 ctttacttgt agctgcggat ggcaaggtgc acgttctcga aggtcagcgg ttccttgtgg
     1681 agaacaggca ggctgtccac gccagtgtat tcccaggcgg ctacataggc gtattcatcg
     1741 tcgttgcgct tagcttcgcc gtccggcagc tggtattcca cgcggaagtg ggcgccgcag
     1801 gattcctggc ggttcagggc gtcatagcag agcagctggg cgaattccag gaagtcggcc
     1861 acgcggcagg ctttttccag ttccgcgttg atgccgtccg ccgtgccggt tacgcgcacg
     1921 ttttcccaga attccttgcg gagctgggga atgcgttcaa tggcgtgggt caggctttct
     1981 tccgtgcggg ccatgccgca gtcttcccac ataatgaggc ccagttcccg gtggaaggag
     2041 tccaccgtct tggtgccctt cacattcagg agcttgttga tgcgttcctt cacttcgtct
     2101 tccgcagcct tgaattccgg ggcggcggtg gtgacggcgc cgggtttggt ggtcgtcagg
     2161 taagcgggca gcgtggcggg aatgacgaag tagccgtcag acaggccctg catcagggcg
     2221 gaggctccca ggcggttggc gccgtggtcg gagaagttgg cttcaccgag gacgtgcagc
     2281 cccttcacat tggacatgag gttgtagtcc acccacaggc cacccatggt gtagtgggag
     2341 gcggggtaga tcatcatggg cgtttcatgg gggtcgtcgt ccgtgatttc ttcgtacatg
     2401 tcaaacagat tgccgtattg gccgtcaatc cattcgcggc ccatgcgctt gatttcatcc
     2461 gcaaaatcta ggaagacgcc cttgccggtg acggccacgc cgcggccgtc gtcgcaggct
     2521 tccttggcgg cgcgggagga aatgtcgcgc ggagccaggt tgccgaagga gggatacttg
     2581 cgttccaggt agtagtcccg ttcttcttcg ggaacatcgg aaggcttgat ttccttctta
     2641 cggatttttt ctgcggtttc acgggacttg ggcacccaga tgcggccgct gttgcggagg
     2701 gattccgaca tcagcgtcag tttggactgg tagtcgccct tgaccggaat gcaggtgggg
     2761 tggatttgcg tgaagcaggg gttggcgaag aaggcaccgc gcttgtaggc cttgtaggcg
     2821 gcagtgacgt tgcagcccat cgcgttggtg gacaggaaga acacgttgcc gtagccgccc
     2881 gtgcagagca ggacggtatc ccctgcgtag gatttgattt cgccggtaac cagattgcgg
     2941 gtgacgatgc ccttggcttc gccgtccacc agcaccagat ccatcatttc atggcgggag
     3001 aacatttcaa tgtgtccctt ggccacttcc ttttccaggg cctggtaggc acccagcagg
     3061 agctgctggc ccgtctgtcc gcgtgcgtag aaggttcgct tgagctgggc gccgccgaag
     3121 gagcggttgt ccagcaggcc gccgtattca cggccgaagg gaacgccctg ggccacacac
     3181 tggtcaatga tgttggagga gacttccgcc agacggtaga cattggcttc acgggcgcgg
     3241 aagtcgccgc ctttaacggt gtcgtaaaac aggcggtaaa cggagtcgcc gtcattctgg
     3301 tagttcttgg ccgcgttaat gccgccctgg gccgcaatgg agtgggcgcg gcgggggctg
     3361 tcctggtagc agaagcattt gacgttgtag ccaagttcgg caagcgtggc ggcagcggag
     3421 gcgccagcca ggccggaacc taccacaagc accgtgtact tgcgcttgtt gttcggattg
     3481 atcagtttgg actcaagttt gtacttggac catttgtcct gaatagggcc ggagggaatt
     3541 ttggcatccg gcatccagtc gcttacggga aaattaatca tgactttgag aggagttgat
     3601 ggttatttga tgatacccag aagaaccgag accggcacgg agatgaagcc caggcagata
     3661 atcgcgccgt aggcgatggc gataaagttg tagaagggcc ggattttgcg ggaatcgacg
     3721 cccacagtct ggaagatgga ctgtaccccg tggcgcagat ggctgaacag catcagaacg
     3781 gccaggatgt agaaggcgga gcaccatacg ttggagaatc cggtcacgat catcttgtac
     3841 acgtcaaagg tttccaccgt accgtcggaa atgaaggtgg tgaactgggc ggggtcgtat
     3901 cccacgcgca gggtgtactg gtacaggtgg tagatcagga acaccaagac ggtcaggccg
     3961 gtatagatca tgtagcggga ggagagcgtc gccttgatgg tgttcttgaa cacgtagggt
     4021 tcgcgggccg catggttttc cagcttcagc tggatggtca gccagacgtg gatgatgaag
     4081 atcaccgcaa gccccgcgcg gattccccag agggctgctt ccggcatgga gtgcaggccg
     4141 tgggcgtagg tgttgatcca ttcagggcct ccgaagatga gaaggttgcc tgccaggtgt
     4201 cccgcaagga acaagaccaa acataacccc gtcagagcca caatgatttt gcggccgatg
     4261 gaggatgtca cgaatgtaca tatggttttt actagtgcat tcataggcgc tctaatgaaa
     4321 taaatgcgtc ttcacaggat gcccggttca agcccggatg gcaagcctct tcttgaattt
     4381 ccggcgcttt tcggattttt gaaaaaccgg ggaaagaggt tgctgtttat cagtttggaa
     4441 tggttatcat tttgttgcct gttccggctt gacgaggctt tccgcatagg cgtatcgtct
     4501 gtgcatgaaa agaagtaaaa aggaggtgct ggacgcggat ttcgcagcgg cgcgcgccgg
     4561 cgttctggat gtggccgcat ttctggaccg ggtggaccgc ggggaagggg aggcggattt
     4621 ccgctaccat gccctgatgg atgttcttcc cctcttgtcc gcatccggcc ccggacgcgt
     4681 ccgggccatt ctggaagccc tttcctacag ggatgacacc gtgccggaaa ccgccgcagt
     4741 caaagcggcc tgcggagccc cgaacctcag caaataagaa tgatggcttt catagaacct
     4801 catatacata tggtgtgccg caccacggac gaataccggg ccatggcgca ggccggctgc
     4861 ctggcggtag gggaaccggc gttctgggcc ggttacgacc gttcgtccgc ggacggtttc
     4921 cgggattatt tcgtacagct tacggaatgc gaacccgcca gggcggccaa gttcggcatg
     4981 gaccattaca catggctgtg catcaatccc aaggaggcgc aggacgtggc tttcgcgcgg
     5041 gatgtgatga aactgattcc ggagttcatt gaccggccca atgtcctcgg catcggggaa
     5101 atagggctga accggaatac ttcccatgaa atgactattt ttgaagagca tctggatctg
     5161 gcggtgcgcc tcaaccagct tgtgctgatt cacactcccc atctggaaga caagcttaag
     5221 gggaccgtaa tgattctttc cgccctgaaa aaccgtccgg atctggaccc ttgccgcgtg
     5281 ctggtggatc actgtgagga acataccttc ccgctggtga aggaggccgg ttactgggcc
     5341 gggctgaccc tttatcccac cagcaagctg aatcccaagc gggcggcgga tattctggaa
     5401 ttgtacggaa tggaccgtgt ctgggccaat tccgcggcgg actgggggga ttccgatccc
     5461 ctggcgctga cggccctggc ctgcgagctg cgcaggcgcg gtttttcccg gcaggaaacg
     5521 gaacgtcttc tcctggaaaa tccggagaca ttcatgggac agtccccgaa gttccggaaa
     5581 gtgtcgtccc gctaattccg cccgaggcgc ggcggagggt acggccctct agtccccgtc
     5641 cgggaaaaag acggtgagga cggcgcccag gatgaccgcc gcgtcatcca gaaggcccag
     5701 cctgccgatt ccgtcaaaca ggaattcgtc gggagtcagg atgtaggcgc cggcggcggc
     5761 cagaaggcat atattccgtt tgttgaaaaa acgcggttct ccttttctgc ttttgaaata
     5821 ccggaacagg cgcagtagca gctgctgttt ttgaaggttc atggatggga acgggggata
     5881 aaggttcaag ttcagccatt ttcccactcc ttttccctgt ttcagggaag gagtctgttg
     5941 ccgacggacg gaaaccgcag cgatccggac cgtgcgggga aatggattgc tgaaaggatg
     6001 ggctgttccg gatgctgagg gaagccgggc tttgcatgct ccggttccgg ctgtcccggc
     6061 atgggaaaaa ggggcgtgta cggaagtggg gcggggccgg aagctcttga aatgaccctc
     6121 ccgggggagc ctgaatgcca tttccccgtc aagtgctggc cgtgagggta cccagcaaat
     6181 agaagcttct tccccctgtt ttttccggca gatgtttgaa cggataagga aaaggccggc
     6241 tcacgatttt gtgagccggc ctttgaatat agggaggcgg acggtacagg cttatgccct
     6301 gcggcggcgc atcatcagcg cggccagtcc cagcaggccc agggaagccg tggcgggttc
     6361 cggaatgctg gcgatttcac tcatcagctg accaacttgt tcctgggaaa ggagggagtc
     6421 gtggatgtag agctgttcga tggattcagc cagtcctgcg tccatgagaa tctgattaat
     6481 ttgctggttg ccgaatttca ggccgctgtt ggaatagtac gtagcgctgt ctccaaaata
     6541 gatgcgggtg ccaagatctc cggtgactac ggaaatggtc agggaacctt ccgtgcccag
     6601 cggggtgtca acgacgggcc cgctgtatga ggtgttgttc cataatccct ggagtttccg
     6661 gtccgtgttc aggcccacgc cccagcttac actgctgttt ttggcgttaa acagagcggt
     6721 ataggtctcc ggagtgttga ttttggacag gtcaagaacc atcgtcacag acataacgtc
     6781 gcggttgttg gcaccgtatc cgttgaaggt tatcccggac aacgtcagat tgctgtcgtc
     6841 agacgtgatg gaaacggaat ctttccgggt gccgaaatcc gccgtttggg aggcaaagtc
     6901 cgaatatccc acgatggagc tatccaacag agcggtagcc gcggtagcgc tcaggctcat
     6961 gccggccgaa agaatcaggg tggataataa tttattcatg gtcagtatct taataaaatg
     7021 attcaaggtt caatgtatgt acttgtgctt gaataacgaa tttggaatcc gcaagcaatt
     7081 aaaaatatta agagttagta tattgtattt ataattcatt gaaaataatg attttttaat
     7141 atctctggtc cttttgtcaa gatgacgggt cagtctttgt tattcattgg tttcatgatt
     7201 gatttggcct ctttttcatt acttgacgga ttccaaatcc gattggggaa ttccaaattc
     7261 gctacaagtt gccatccaaa aggaataata aatatgaaga aaacactgac atttttaatc
     7321 gcgatgggaa gctttgctgt ttcctcggag gcagcgaccg tttttaatta ttacactccc
     7381 ggtacggata attacaatag taccatccat gggttttatc ttggcctggg gtcttcttcc
     7441 ctggctcctt ccgattcctc ttctccctcc tccctgtccg gagagatcag actggacagt
     7501 tttacgctgc gcggagccgc caacaatttg ggcgctaatg tcacttacgg cttcctggtg
     7561 ctgaatggct ccgacaattc ggtcatcggc tggagcacca atacgggaac tactgcagca
     7621 gggattaatc tgacgttcag tttttcttcc ctggatggtt ctcccctgct tcttgacgcg
     7681 gcattgacat accgtttcct ggccgtgagc cagtccgtga tggacttgat gcaggatacg
     7741 tctaaaacgt atttatatgc tgcgggggga acagccgccc ctactgctaa cacggaagga
     7801 gataccgtaa cgatcagcgg tggattgact gctcccggca tccgcggcca ttatgacgcc
     7861 gagggagcac ctggtgattc tgtcgttatt acgggagcca acggaaccaa tactttcagc
     7921 ttattatccc cgattttcac ggaaatccga ggggaaatgg tgccggaacc agccacggtt
     7981 tccctgggcc tgctgggact ggccgcgctg atgatgcgcc gccgcagggc ttgagcttcc
     8041 tgatggcgaa aaatcggcgg atgagagctg ttcttgcgga acagctcttg ttttttatat
     8101 ccagagagga agaattgctt atccgtatgc gggattcatg ccctccggaa ggtacggaat
     8161 ttccgggggc agggggccgt atccggtttt ctccgcatgg cggcaatttg ctggaaacgt
     8221 ttttgagacg caataccgga aagctttttc tttaccggaa aatgccggtc aaattcggca
     8281 gcgcgctttt cgtccatatg gtacacggca gcttccacat agcggccttt caggccggat
     8341 agggaacccc tttgcagcgc acagacctgg agggccgccg catacctatt atccgccgtc
     8401 ctattccccg gcgctggtat tccggaagaa cggcaatggg ccccatgccc agcacttcat
     8461 attcttttcc atcgtctgcc ctgatgacgg acgttgcatc aacgatgttt cccgacgatg
     8521 cggctgccgt ggacggcgac tgcatccagc tccgggatga aggaaggact gacgcgcatg
     8581 atatggagca ggtaatgttc attgcagccg gggacgaaat agtttcagaa cgcttctctc
     8641 gtgacatgtt ccgtttcggc atggtctgag gattgttccg ttcttaatgc aatggtcatg
     8701 aaagattgtt ctttacggct cccccttgga gaaattccag aggcggtgca tcgtcataat
     8761 gtccggaatg ttcatggggc gcaccacgcg gaacccgatc atgcctccgt ccgtcaggta
     8821 ccagatgctt ttagggtttt gaggatcctg acggttccag gcgggggtgc tggcgcggcg
     8881 cgcagcgctt ctcaggctgt ccgggtcgtc ttcccacgaa ccgccgcgaa cgatgtgagg
     8941 ggcgccgggg atgatgacca gggggtcttt cgcgggcaag ccgctccgtt tgccgtaggc
     9001 atccggaacg taagagtcca aaacccattc cgccacattt ccgtgcatgt cccggagtcc
     9061 ccacttattt ggttttttag agcctgtttt ctggtagcgg tcattggaat tgttccagta
     9121 ccaggcgtac tggtccagag aggcttcccc gtttccgtaa gaataggcgc cggcggaacc
     9181 ggcccggcag gcgtattccc attccgcctc cgtgggcagg cggtagtaat gcccggtctg
     9241 ggcgctcagc cattcgcaga atttgctggc ggcgtggtgg gacatggaga tggcgggcag
     9301 gccgtgttca tagccgtggc ccatgcccag gttcatggcg gcgtaggggg cggtaggctg
     9361 cgtgacggag tcccacagtt cgtcatccgg ctgttcctcc agaagctggc cgtccttggc
     9421 gcgcggacgc ccgttttcca tgaaggccgt ataaagttcc caggggattt ccgtttccga
     9481 gatccagaag ggagagatgc tcactttatg ctgcggacct tcgtccggtt tccggtgcgg
     9541 ctcttccgcg ggactcccca tgaggaacgt tcctcccggt atggcgacca tgcgcaggga
     9601 agctcccgcc gcgggaaccg tttccgtgta ggattcaaaa cgtgccggat ttccggaagc
     9661 ttcaatgagc tgatggattt ggcgcgtcgt gccgaccagc tcccgggacg gcaggtcatc
     9721 cggaatggga agggcaggac cggcagcgcg gtccagttcc cgtttttgca gcgcggatcg
     9781 gctttctccc cactggcgtg cgctggtaat gcgcgcggca tcttccgtgg ccgggcgggg
     9841 ggaattattt tcttcccggc acccggccag cagggcgctt cctcccagaa agcaggaaac
     9901 aaggaaaatg ccgcgcatgg aatggtgaaa accggaatgc cctacatcgt catgcctccg
     9961 tcgcaggcaa tgacctgccc ggtgatgtaa cgggcatcgt cagaggcaag gaaggccgtc
    10021 agggcggcga tatcttccac ggaaccttgt tctttcaaag gtattttctt aacgatttct
    10081 tccttgagat tgtcgggaat ggcattggac atttccgtgg agatgaagcc gggagcaatg
    10141 gcgttgcacg tgactttgcg cggagcgaat tcctgagcca gtgatttggt gaaaccgatg
    10201 aggcccgcct tggaagcggc gtaattagcc tggccgatgt tgccgacgag accgatgacg
    10261 gagctcatgt tgatgatgcg cccggccggg gatttcatga gaacgcgctg gagggccttg
    10321 accgtattga acgcgctttt caggttggtg tccagaacgg catcccagtc ttcctccttc
    10381 atgcggagca tcagggagtc ccgcgtgatg ccggcgttgt tcaccaggat gtcaatctgc
    10441 gggaagtctt tcaaaatggc ggccatggtt tcctgaacgg ccgcgtaatc cgctacgtcg
    10501 caggggtagg ccttgcagga atccggaaat tccttgttga tttcttctgc ggcccccccg
    10561 cagctggatg gactgcggct gatcaggatg accctggctc cttccgaagc gaagcggcgc
    10621 gcgacggcat tgccgattcc gcggcccgcg ccggtaacga tggctgtttt acctgctaac
    10681 ttttgcatgc tgcccacagt aaacccgttt ttcacggttc cggcaagctt gaaatggact
    10741 tggccgcgca ggaacccata cggggaaagg gcgtgccggg aatgaaaaaa gaggggggag
    10801 aaacggggcg gggggctact gtccggcctc ttcattttcc cggagtgcac cggggggcgc
    10861 cccgtcttca tccggttcta ccaggtcgct gaattcatcc gaattttcca aaatgtcctt
    10921 taaggcggcg gaaccgtaat agcgggcctc aaacaggcgt ttgccttcct gcctgcagcg
    10981 gttgtccagc atttccattc gttttttcat tttttctatc aaggcgtctt ctttctcctt
    11041 ttccgcatcg ttcaatttat cctgaagctg gaggaaatgc cggatgtcct tctgaatgtc
    11101 ctgcagcgtt ttgacggcgt tgtccgcgct ttccttgtcc tgaacgcctg ccaacgtctg
    11161 ctggatattg atggcaaagg aaaaggcctg gttgatcagg gattccgcgg aaggaatttt
    11221 ttccgccgga gccgctgctg cgggggaagc cgttccggcg gccgtttcac caaatgcaag
    11281 agaggctccg gacagaagcg cagaatataa gagaggaaca agaaaagcct tcatcctgtt
    11341 cttttaaggc aggatgaaat ccacggcaag gaaaaagggg aaactgaaaa aagagcctta
    11401 tttcgccgtg atgccgcctt tttcatcgtc cagaatgcct gacttttcca gatagtagtc
    11461 atatccgcct gcgtaggcgg tgatggtccc ccggttcaca tgcagggttt tttgtgccag
    11521 ggaacggatg aagtgcacat cgtgggagat gaagaccagt gttccttcat aatgcttcag
    11581 agcctgcacc agggcttcta cggacaaaag gtccaggtgg gtggtcggct cgtccatcag
    11641 caggaggttg ggcggatcca ccaggaattt gaccaagctg agccgcgatt tttccccgcc
    11701 ggaaagaacg ctgacgcgtt tttccacatc cagcctccgg aacaggaagg aacccaggat
    11761 ggaacgcgct tcttcctccc ggatttcagc gctgcatttc atgatttcct ccagcacggt
    11821 attttccgga ttcaggtttt ccgttcgcgc ctgggagaag tagccgatgc gcgtcgtggt
    11881 accgggagtg cgttgtccgg agtcaatggg gatgatgccc gccaggattt tgagaagagt
    11941 ggatttgccc gcgccgttcg ggcctacaag aacagtgcgc tccccgcgtt ccaccagcag
    12001 gtccaggttt tcataaaccc tgcggtcgcc ataggattgg cagacttttt ccagctcaat
    12061 gactttctgg gtgctgcgcg gaggctgggg gaagttgaat ttaaatactt tcctgcgggc
    12121 taccggtttt tgaatgattt tcatcttttc cagctgcttg atgcggctct ggacttgccc
    12181 ggctttggaa ttgatggagc ggaaacggtc aataaattcc tgaatgtgcg ctatttcctt
    12241 ctgctggttg cggtaggccg cctgaagctg ctcgaagcgc acgtcctttt gttggaggaa
    12301 gtccgagtaa ttgccgcggt attccaccag ttcttcgttg tcgatgtcgt acacgctttc
    12361 caccagctca tccatgaaat cccggtcgtg ggaaatcatc aggatggctc cggggtagtt
    12421 tttcaggtat cgctggagcc acagcaggga caggaggtcc aggtggttgg taggttcgtc
    12481 cagcatcagg aggtccggct ccaggacaag gagcttggcc aggtacgcgc gcatgatcca
    12541 gccgccggac atttcccggg cggggcggtg gaagtcgctt tcccgaaagg ccagcccttt
    12601 gagaattttc ttggctttgg gctccagctg gtaaccgttg gcggcgttga aggtgtcaat
    12661 ggcttccgcg tattccggcg tatccgtttt gttggcgttt tccgccgtcc ggatggtgtg
    12721 gatggcctgt tccatttccg gcgtgatgcc cagggcgatt tccagaacgg tttcatcctt
    12781 cggttcgctg gcttcctggg gaagatagcc cacgatggcg tattcatcca tgctgatgga
    12841 gccttcgtcc ggcgtgtctt ctcccagaat catgcggaac agggtggatt tgcctgctcc
    12901 gttggggcca accagagcca cccgttcccc ccagttaatg gtcatttccg tttccctgaa
    12961 caaggtccgt ccggcgtggg attttgtgag atttttgatc gtcagcatgg tgaagagagg
    13021 atgtattcta ccgggatgga aaggggaagg caagagccgt cagggcggag gcaggcattt
    13081 ttgaaagctt tactggattt ttacgcgtag tctgctagcc ttggcgcgcc atgccgacca
    13141 cgcagacatt caggcttttg cttgctgccg cccttttgtg cggatggagt tcctgctgta
    13201 ctcctccggc ggaggattat atacaacaac cttacgtgca gcagcaaatg tccgggctgg
    13261 ctaatgcctt cctggcgctg ctgccgccgg atcaggcctc tcttcccgct gccggagcgg
    13321 aggccaggtg gctggcggac acggccgtgg tccagtccgc cgcgattgcc cgggacaaca
    13381 ggactgtgct gtttggctgg ctgaacaata ttctggtcaa ttccaacctg cgcgacaggg
    13441 ggctgtgctg gcaggtccag caggatttgt accgggacct gcgccgccgc cccgtgaagt
    13501 atttccgcat agggctgacg attcgagacc gaggaacggg cagggagcac agttgcgtgt
    13561 atgtcaatgc cgcggggaag ggattgcagg gctccattgt tctggatgcc tggaagaact
    13621 gcgggcatct ggtgacgctg acccagaagg accgggaagg cggcaaatgg gaggaggact
    13681 ggcgggaacc atttgtttcc aaggcctttc cggagggcca ttcctacggc atggaacatc
    13741 acttggtctg gcccgggtgg gccaggaaac gccccatgct ggttcagcgg atatttcagt
    13801 ccgatcagca gaatgaggcg aaggcggccg ctgaataaag gggaagcctg atccggcagg
    13861 aaccggcaca cggtgctgcg ccgcggcggt ttgcggtatc cgccgttttt aaggaaaatc
    13921 ccggcgaatc ggcaaatggc ggagggaatc cggactcagg gcaaataaaa acgcactcag
    13981 tgcgtacacc gagtgcggat taattggata atttgctagt gttgcagggc aaaaccccgc
    14041 tgcaaactta cttgcccttg gcctgcacaa ccggagcggg agcaggagcg gtggtttgct
    14101 gttgctgctg ctgctgggag caggaagcga ccaggcaagc ggcgccggcg atggcgagga
    14161 tagcgatgtt cttcataatt cgaattaaat acagtgtttg ttaactactg gaacctccgc
    14221 atccacggag gtttgctggc accaatgtaa atggtggcaa gtagaaatca agagattttc
    14281 ttgttccatg tcacggcatt acag
//
