LOCUS       gnlProkkaGDNKDNGG_58   12808 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDNKDNGG_58.
ACCESSION   gnlProkkaGDNKDNGG_58
VERSION     gnlProkkaGDNKDNGG_58
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 01:24:59
            Original ID  :: gnl|Prokka|GDNKDNGG_58
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1638
            Orig. end    :: 14446
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12808
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10267]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10267
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12808
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12808
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(501..2771)
                     /gene_functions="transport (smcogs)
                     SMCOG1117:sodium/hydrogen exchanger (Score: 232.9; E-value:
                     9.4e-71)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_4"
                     /transl_table=11
                     /translation="MSHLAPLIADLALILICAGIMTLLFKKLKQPLVLGYVVAGFLASP
                     HMAYTPSVIDTANIQTWADIGVIFLLFALGLEFSFKKIVKVGGAAIIAACTIIFCMILL
                     GVAVGTGFGWKRMDCIFLGGMIAMSSTTIIYKAFDDLGMRKKQFTGLVLSVLILEDILA
                     IVLMVMLSTMAVSHNFEGMEMLESIAKLLFFLILWFVVGIYLIPGLLKRCRKLMSEETL
                     LIVSLGLCFGVVVMAARTGFSAAFGAFIMGSILAETVEAESIERLVKPVKDLFGAIFFV
                     SVGMMVDPAMITEYAGPIIVITLAVILGQSLFGTLGMLLAGQPLKTAMQCGFSLTQIGE
                     FAFIIASLGVSLRVTSHFLYPIVVAVSVITTFLTPYMIRLADPASNLVDTHLPEKWRKF
                     LTRYASGSQTMNHESLWRKLIFALVRITVVYSIICVAVIALAFRFLVPFVHEGLPGGWG
                     SLLAAFIIILCIAPFLRAIMLKKNHSEEFMTLWRDNRGNRAPLVATIVLRLLLGVSFVM
                     FVIAGLFKMSVGLVFGVAVLLVTLMILSRQLKKQSIMIERTFFQNLRYRDMRAEYMGEK
                     KPEYAGRLLSRDLHLTDFEISGESEWAGRTLAELNFGKKYGIHVVSILRGKKRINIPGA
                     SVRLFPQDKIQVIATDEELNTFGLEMDKVSAMNADVIEKSEMILRQFYVDGQSPFLNKT
                     LKEAGIREKYRCLIAGVERGGETLHAPDPHEPFVEGDVVWIVGESADVYKLVGLKCEGF
                     DMG"
     CDS             complement(2948..4096)
                     /locus_tag="ctg58_5"
                     /transl_table=11
                     /translation="MKKLLFIDRDGTLVIEPPIDYQLDSLEKLEFYPKVMRNLGFIRSK
                     LDFDFVMVTNQDGLGTTSFPEETFWPAHNLMMKTLEGEGITFDDICIDRSMPDDNAPTR
                     KPRTGMLTKYLDNPDYDLSHSFVIGDRPTDVELAKNLGCRAILLQDDTASLKPVSEGGG
                     AACDGLEDYCALATRDWDKVAEFLFAGERTAEVRRTTKETDIYVSLNLDGDGHCDIATG
                     LGFFDHMLEQIGKHGGMDLTIRVKGDLEVDEHHTIEDTALALGDCLYQALGSKRGIERY
                     GYALPMDDCLCQVCLDFGGRPWLVWDAEFKREKVGDMPTEMFLHFFKSLSDAARMNLNV
                     KAEGQNEHHKIEGIFKALARALKMAVKRDIYHFELPSSKGVL"
     CDS             complement(4319..4492)
                     /locus_tag="ctg58_6"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEV"
     CDS             4541..4756
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             4770..8348
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVRTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTKLA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             8595..9521
                     /locus_tag="ctg58_9"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             9548..9988
                     /locus_tag="ctg58_10"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             10001..10267
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_11"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.8e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             10276..11439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_12"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.3e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             11462..12808
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 157.2; E-value:
                     1.1e-47)"
                     /gene_kind="transport"
                     /locus_tag="ctg58_13"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNP"
ORIGIN
        1 taccgtggcg tgtgcaaccg gacattgccg gtggaggata cttttatgat cttgcacccc
       61 accagataga tttgttacag gaaatcttcg gatgcatcct cgaagccagc ggatacaaga
      121 gcaaccgtgg cggactatat cctgccgagg acaccctaag cgcatgtttc cagtttgaca
      181 acggactggt gggcagcggt tcttggtgtt ttgtcgccca cgaatctgcc cgcgaagatc
      241 gtatagaaat cattggagac aaaggcatga tttgtttctc cgtgtttact tatgccccca
      301 ttgcgctaca cacagaaaga ggacgtgaag aaatcattgt cgaaaatccc acctacgtcc
      361 aacaaccgct tattcaagca gtggtagacc acctactggg caagtcaatc tgcaactgtg
      421 acggcgaaag cgctactctt accaactggg taatggacaa aatattgaac aaactctgat
      481 tagtgttcat gaggcacacc ttaccccatg tcgaaacctt cacatttcag gccaaccagt
      541 ttgtacacat cggcactctc gcctacaatc cataccacat ccccctctac aaaaggttca
      601 tgcgggtcgg gagcatgcaa ggtctcccct ccccgttcca caccggcaat caagcagcga
      661 tatttctccc gtattcctgc ctctttcaag gtcttgttca agaaaggaga ttgcccgtcc
      721 acatagaact ggcgtagaat catttcactc ttctctatca catccgcatt catggcagat
      781 actttatcca tctctagacc gaaggtgttc aattcctcat ccgtagcaat aacctgtatc
      841 ttgtcctgcg ggaaaagacg gacagacgcc ccgggaatat taatccgttt cttgccccga
      901 agaatggaga ccacatggat gccgtatttc tttccaaaat tcagctctgc caatgtcctg
      961 cctgcccatt ccgactcacc ggaaatctca aaatccgtca agtgcaggtc gcgtgaaagc
     1021 agacgccccg catactccgg tttcttctct cccatatact cggcacgcat gtcgcggtac
     1081 cgcagattct ggaagaatgt cctctctatc atgatagact gcttcttcaa ctgacgggag
     1141 agtatcatca aagtcaccaa taacaccgcc actccaaata ccaaccccac agacatcttg
     1201 aataaaccag ctatcacgaa catgacaaac gagacaccca gcagtaaacg cagtacaatg
     1261 gtagccacca acggtgcccg attcccacgg ttatccctcc ataaagtcat gaactcttcc
     1321 gagtgattct ttttaagcat gatagcacgc agaaacggag ctatacacag aatgatgata
     1381 aaggcagcca gcaaagagcc ccatccacca ggcagaccct catgtacaaa aggcaccaaa
     1441 aaacggaatg ccaaagctat caccgccaca caaatgatgg aatatacaac cgtaatcctg
     1501 accaatgcaa aaatcaactt cctccacaga ctttcatgat tcatggtctg agaaccagaa
     1561 gcatagcggg tcaagaactt tctccatttt tccggtaaat gcgtatccac aagattggaa
     1621 gctggatctg ccaaacgaat catataagga gttaggaaag tagtgatgac agacaccgcc
     1681 accacgatag gatacaagaa atgactggtg acgcgcaacg atacacccag ggaagctatg
     1741 ataaaggcaa actcacctat ttgcgtcaga ctgaaaccgc actgcatggc cgtcttcagc
     1801 ggttgccctg ccagcaacat acccaatgta ccgaagaggg attgcccgag aatgaccgcc
     1861 aaagtaatca cgataatagg tccagcatac tctgtaatca tagccggatc taccatcatg
     1921 ccgacagata cgaagaagat ggcaccgaac aagtccttga ccggcttcac caaccgctct
     1981 atgctctccg cctctactgt ttcggcaaga atggagccca taataaatgc gccgaaagca
     2041 gccgagaacc ccgtacgcgc agccatcacc accacaccga aacagagtcc gagagataca
     2101 atcagcaagg tttcctcgct catcagcttc cggcaccgct tcagcaatcc gggaatgaga
     2161 taaataccca ccacgaacca aagtatcaaa aagaacagca atttggcaat actctccaac
     2221 atctccatac cctcgaagtt atgactgact gccatcgtgg agagcatcac catcaatacg
     2281 atggcaagaa tatcctctag aataagcaca ctgagcacca atcccgtgaa ctgcttcttg
     2341 cgcatcccta aatcatcaaa cgccttatag ataatggtgg tggacgacat ggcaatcata
     2401 ccgcccagaa agatacagtc catccgtttc cagccaaaac cggtacctac agccacaccc
     2461 aacaatatca tacaaaagat gatagtacac gcagcaataa tcgctgcccc tcccactttc
     2521 acaatcttct tgaaactgaa ttccaatccc agtgcaaaca gcaggaaaat aacacctata
     2581 tccgcccaag tctgtatatt agccgtgtca atcaccgacg gtgtataggc catgtgaggg
     2641 ctggcaagga atcctgcaac tacatatcct aacaccagcg gttgcttcaa tttcttaaaa
     2701 agcagggtca taatccccgc acaaatcaat atcagagcta aatcagctat caaaggggct
     2761 aaatgtgaca taacactact tatctattaa tcagagatat acaactgcaa aactctgcaa
     2821 tacatttgca gtagctctgc aatacatctg cagtggctct gcaaaagcct tgcagcgtca
     2881 ctgcaactgc tttgcagcaa cactgcaaaa ggtatgcagt aactttgcag cagttatctg
     2941 tacgattcta caacactcct ttcgagcttg gcagttcaaa gtgataaata tcccttttca
     3001 ccgccatctt cagcgcacgt gccagcgcct tgaagatgcc ttctatctta tgatgttcgt
     3061 tctgcccttc ggcttttaca ttaagattca tccgagcagc atcgctcaag gacttgaaga
     3121 aatgcaggaa catttccgtc ggcatatctc ctaccttctc gcgcttgaac tcggcatccc
     3181 ataccagcca cgggcgtccg ccaaagtcaa ggcacacttg gcaaagacaa tcgtccatag
     3241 gaagggcata gccatagcgt tcaatgcccc gcttgcttcc taaggcctga taaaggcagt
     3301 cgcccagagc aagggcggta tcttcgatgg tgtgatgctc gtccacttca aggtcacctt
     3361 tcacacggat ggtgaggtcc atgccaccgt gcttgcctat ctgttccaac atgtggtcga
     3421 agaagcccag tccggtcgcg atgtcacaat gcccgtcacc atccagattc aaggatacgt
     3481 atatatctgt ctccttggta gtgcgacgta cttccgccgt acgctcaccg gcaaagagga
     3541 attcggcaac cttatcccaa tccctggtgg cgagggcgca gtaatcttca agtccgtcac
     3601 aagcggcacc gccaccttcg gaaacgggtt tcaatgacgc cgtgtcatct tgcagaagaa
     3661 tggcgcggca gcccagattc tttgccagtt ccacatccgt aggccggtcg ccaatgacga
     3721 aactgtggga caaatcgtag tccgggttat cgaggtattt ggtaagcatt ccggtacgcg
     3781 gcttgcgagt cggtgcattg tcgtcgggca tgctgcggtc tatgcagatg tcgtcgaagg
     3841 tgatgccttc gccttccaat gtcttcatca tcaggttgtg tgccggccag aaggtctctt
     3901 ccggaaagga agttgtgccg agcccatcct gattggtcac cattacaaaa tcaaaatcca
     3961 gcttgctgcg gatgaagcca agattgcgca tcactttcgg atagaactcc agcttctcca
     4021 gggagtccag ctgataatca atgggcggct caatgactaa agtcccgtca cggtctataa
     4081 aaagtagttt cttcatttta aaggatattt ttttgaggga ataaagggag ttatcgggag
     4141 ttagaagtga taactctcct aactcctata aatgaaagag acgtgagcct ttcccaaaaa
     4201 aaatagagaa acatagatac acttaaacaa aaaacaatta tctttgtcac aaatccgcta
     4261 tagcgtagtg ggtttattta catattagta agagcattat tgaaattatc ttctttattc
     4321 aaacttcgca actttgaaaa tttccctgaa gataacaaca aggatgctca cgtctatgtt
     4381 tatatggttt tctcccatca ggggggatag tatatacaca aacgacgtga gtgactgttg
     4441 tatatccagg gaaagggcaa tgcgaaggcc tgaataaagg atatacaaac atagttactc
     4501 acgttttttt tattgtttaa cctttaaata atttgtgtat atgaaacaga acacaccaga
     4561 cggtagagaa gcatacatca ctccgtctat cgaagttatc aaaatggaga atgaaggagt
     4621 cattgcaaca agcggcgaac cttaccatcc cattacgcgc tcctattcgg gcagcacctc
     4681 tacccatagc tacaattcgg catccagcag cgacttggaa gacctaatca atgacatctt
     4741 aaccgtagaa aactaagggg gacttcatta tgatgaaatt aagaaacctt atgcaagttg
     4801 cctgcatggc aactgctgcc ttgaccgcat tcagttgcag ccaagaggaa tttgaaaaca
     4861 gcgggtggaa aggaaacatc accgttaacg caacgtttga aggcgcaggt accgacaccc
     4921 gtactaccgt aaacgatgaa tacaagattc tatggcaaga taccgatgcc ctagggttgt
     4981 tctgtagtaa tgcagaaagt aattatagca atacaaaatt agaatatgca agcggtgctg
     5041 gtcaaacttc cgccactttc aacggcagca agccaagcgg agaaacggct gtattctcca
     5101 tctatcctta ccaacaaaac atgagcgtaa gcggcaatac attgaccatg actctacctg
     5161 ccacgcttac aaattataac ggcagcagca atggcccgat gtatgccaag gtgacaaatc
     5221 ccgacaatct gagcgctctg tccttcaagc acatggcagc catgataaaa ctgaccgtca
     5281 acaagattcc ggcagaggcc actactttca agattattgc ctccaataac attgcaggta
     5341 cttgtacggt agacttaacc gcagcagacc cgatactgac ggtagcaagc aatggaagca
     5401 aggaaatcac tgcctccttc actgcttcaa acgatataaa atcgcgcaac ttctacattc
     5461 ctttgcccac aggtacttat agttccatca ctgcccaact gacgaatgga agcgacaagg
     5521 tatattttac caagacgctt aatgacaaaa tcttagggag aagagacata ttggtagtac
     5581 ctcctttgga ttgcgttgtt gtagatgcta caacccccag tgcgcttagt acagctttag
     5641 ctgattcaaa aaatctccca caagaagcac cgacagcagc aaccgtaacc gacattgcag
     5701 tcagcggcag cttcaatacc acttctggca gcaacgacgg catcgccatc ccggttttac
     5761 agaactcgga catcaacctg acgttcaata cagccccaac gaccagtact gccgctccgt
     5821 tgacgctgac cgacaagacc aataccagcg taagtgctcc cgccgccact gccaccaaca
     5881 gtgtatcctt ggctgtaccg gaaaccacag cagagcaaga agctccttct gtagccatca
     5941 ccatgccaag caccaccgtt acattggcag cagtaggcaa taaagccact tacaatgaag
     6001 tgactgccac taccgcccag cagacattga ttatcaatgc aggcgtcacc gtaaagaagc
     6061 tgactgtaaa aggcggtaac ttgaagatat atggaaaggt agaacaattg gtacacgatg
     6121 ccggcgatac cacaatctat ataataaaag gaactgaagc atcacttccg gcaacaatcg
     6181 acagcaaatt tgtagttcaa tccgacgtgg cagtcctaaa gaccgctttc gccaacggcg
     6241 aagattttaa attgtccgcc gatgccgaca tcacagggca aagcgtcagt gtacccgccg
     6301 gaaagtccgt ggttcttgac ttgaacggat atacactgac tgccgacaac agcgcaacag
     6361 gcaaaatcat cgtcttgggc aagatgacac tgaaggacag ctctaccgag aagaaaggca
     6421 agatagttgc cagccaggat tatacagcgg cttcttataa tggcagtctg attgaaatag
     6481 ccggtgaaga tgcctccatg accatggaaa gcggcaacat cagtgcagtc agagagactc
     6541 cggacagtaa cggccaatat ggcgtcggag tgacggacgg tggagacttc accatgacag
     6601 gcggcaagat agaagccgga tggtttgcag tggcaggcaa cggcaattac aagacgcaga
     6661 actccatcat caacatcaca gacggagaac tcatttctac tgctgactat gcagtctatc
     6721 tgccccaatc cggcacaacg accatcagtg gcggcaaggt ttatggtgcc gcaggaggtg
     6781 tatgcatcca acgaggcact ctgaatgtgg aaggtacagc cttgattacc agtaaaggca
     6841 caggtagcac cggcaactgg ggcgacggta ccggaggact ggactgcgcc gccatcaacg
     6901 taagtggagc atatggcatt gccacagtaa acatcaaagg cggtacactg attgccgaag
     6961 caaagtcact catcacagaa ggcaccactt atacaccggt catcaacgtt accggcggta
     7021 cattctccga cccaagcgcg ctgaagtaca tgaaggcaaa tgcaaatgtg aacataaagt
     7081 tgaccgccga caagacctgc ccgggattca agaccacaag cggacaaacc ttgacgatgg
     7141 acttaggcgg caagattctt acacttgctg acccgaccgt aggttccacc ggcaccgaaa
     7201 cgaacagctg tcaattactc gaaggttcaa acgttacttt caagaacgga acgctgaaga
     7261 gtgacaacaa caaaatcatg attcagaact actgcaacct gacattagat aatatgacag
     7321 tagaagacac aaatgcccaa tacgtagtaa gcaacaattg tggcaacata agcatcaaca
     7381 ataccactat caacgcagga agcaatgcga atcaatttgc attcgacgta tgcggctatg
     7441 caaagtacac tgctggagtc acggttacgg taagcggtac gagcgtcatc aatggaaaag
     7501 tggaaatttc caagagtgca ggaaataccg aacttatgaa gctgaatatc acaagcggta
     7561 ctttcaacgg tgacttaaag gtagatgcat ccgtgagaac cgaaaatgcc caaagtatca
     7621 tctctgtttc cggaggtaca ttctccgacc caagcgtact gaagtacatg gcaaccaacg
     7681 caactgtgga tataaaactt ctctcaaata tcaacatcgc caagacgaag cttgccacag
     7741 gctacatatt gaatgctgca aacgcaacgg caaacttaaa cctgaatggc cacgacatca
     7801 tcaattcctc agaaacagct gatgccactc ctttcacaca aatctttact gtacagaacg
     7861 gaacactaaa catttcaggc aacggcaatg tgaagtgcga tgcatctgct acagcgaaag
     7921 acgatggtta tcgcatggta attgaagccc gaggatacgg gacagtaaat attcatggtg
     7981 gttcttacta taacacccag aaactgaaca cccagataga cctgatttat gcaagagaga
     8041 atgggaaaat caatatctat ggaggaacat ttgaatccgg caaatatggt acacccaaca
     8101 acgacacgga tggcagatac tgggtactga acttaaagaa tacagacaag aacactgcca
     8161 gcatccaggt gtccggtgga acgttcatca atttcaaccc ggcaaatccg aatatggacg
     8221 acaatgagtc ctatttggta acaggctacg aggttacccg tgacggcagt gtatatacag
     8281 cagcccacaa agtcggtgat gggaggaaag aatatattgt tggccaaaca agtcaggaga
     8341 accgataagc caaattctaa gaaaggaagc aatatatcct cgcaaaccaa acgaagagat
     8401 atcggaatcg ccttattact atcttttaga tgcggcggac agcggatttt cttttataga
     8461 tctgcgtcct ccgcgtctaa agaatgacaa caagacagtt gaaaaatctc tcaaatcttc
     8521 ctcattcaca caaacattca ttatttttct gagtagccca aagtatcatg aataacaact
     8581 aacaatcaaa acatatgaga atacagatat tggattatca agtaggaccg cacacctttc
     8641 gcatggtgaa accttccgac ttcaatatat tcaaggcgct gccttcactg attccgttca
     8701 tcacgacaat agacacgacg caaaaagtaa tctttgaaac agagatagac gatgacgaaa
     8761 caacgacaaa acgaaccata gcgaaaactc ccgatgatat atgtttcaac tgggaagatg
     8821 ccgattgcat cattcgccct ttgccccaca gctcacacct tgtatccatc accccacgga
     8881 aaagcgggaa aaactattgg atggagtgca acgataactt caggcaatgc ttcatccacc
     8941 taccggcctg caggacagaa acaccggctc cggaaaacga aacgaacttc gtactgaaca
     9001 acttcttgat gatgctctat gccttcaatg ccgcccgcca ccatacactg ctgatgcatg
     9061 cctcggttgt cgctactgaa acaggcaaag gctacctctt cttagggaaa agcggcacgg
     9121 gcaaaagtac gcacaccggg ctctggctgc aacagttctc ggactgccat ctactgaacg
     9181 atgacaatcc gatagtacat gtggacagcc tcggcaagca agccactgtt ttcggttctc
     9241 cgtggagcgg aaagacacct tgctatcgga aagaatccat gaccgtaggc gccttcgtcc
     9301 gcttggaaca agcaccgcag aatgaaatag agcaagagag agcagcacat gctttcgcca
     9361 ccctcctccc ctcctgctct tgcctaaagc agaacaagga aatctataac gccattgtcg
     9421 ccactgtgac ggaacttgcc acgctggcac ccgtctatca tctgaaatgc ctacccgacc
     9481 gtgaagcgac ggaactttgc agaaagacgg tagaaggata agttatgaat gatgaactga
     9541 acagccgatg aagaaaagca ttcccaacga gatattgctt cccgaagtgg cgcgtctcat
     9601 caaagaggga catacagtaa ccatcaccgt gcggggcaac agcatgaatc ctttcttagt
     9661 ggaccgccgt gaccgggtga cactgggcga tttcaccaca gaacagctgc aaccgggcgt
     9721 caccgtactg gcacgcgacc tgacggaacg catcgtcttt caccgcatca tccgtcggaa
     9781 cggagacata ctcatcctgc aaggcgacgg caacctcgcc cagaccgaag aaaccgacat
     9841 cggacgggta atgggcgtca tgaccgaagc catgcgaaaa gacaaacggt acaccgccga
     9901 cggcaaagtc tggaagctct actcctactg gtggatgaag ctaaaccccg ctcgccgctg
     9961 gctgctcgcc ctgttcagaa gaatataaaa caaaataacc atgaaaatca aacaaggatt
    10021 tatcctgcac cggataggcg atgactacat catcatgcaa gacggctcgt cgaacgtgga
    10081 cttcagcaaa gtcatcagcc tgaaccaaac ttccgccatg ctttggcaag agatagaaaa
    10141 caaagagttc gatacagaca gcgtgacaga agccctgacc agccgctatg atgtagataa
    10201 cgaatcggcc cgtcgcgatg cgcagaagtt tatcgactcc cttgaccgcg aaggaatcat
    10261 agaataagga cggatatgca acacgctttc ttttcattgg tacgctccgg cctgtggggc
    10321 actccggcag accgacaact cttccggtcg gtctcgccgg acgactggga aaccgtgtac
    10381 cgcatggcaa actcacaagc cctgcttgca ctgacttttg acggcataag cagtctgccg
    10441 gccgaactgc gccctccacg cgtcctctat ctgaaatggg ctgcccggac tgcacagata
    10501 gaacaagcca acaaacgcct caaccagctt ctgcccgaac tcaataccct ttaccgggaa
    10561 gccgggctgc atcccgtact gctgaaaggg caaggcatcg gcaccaacta ccgcactccc
    10621 ttgcaccggc aatgcggaga catcgacatc tatttaggaa aacaagggca acccatagcc
    10681 aaccgcctcc tgctgcaaca aggcgccata gtcgagggag aagcgtccga caagcatgct
    10741 agctacagtt tgaaaggagt acacatcgag aaccaccgca tcatcctccg gctgaacagt
    10801 ccgcttgcca accggtactt tcagcagatt atcagaaaat ggtacccgca ggaaacagac
    10861 tatgccctat tctccgaaac cgggaaagag gactcgaagg ccgtcagtat cgccatacct
    10921 ccggccacct tcaatgcact ttatatcttc ctgcatgcct ttgtacattt cctgaacagc
    10981 ggaatcggcc tgcgccagct atgcgactgg acttgtctgc ttgccaatcg ccacaaagaa
    11041 atagatgcca ccaccctgct tcgccagttg caggacctcg gactattgca tgccgcacaa
    11101 gcattcggct acattgccgt cacccgactg ggattgcccg ccaaccggct tcctttcccc
    11161 ttggaaggca ccaagcagat aggagaacaa ttattggaag acatcctgtc taccggtaac
    11221 ttcgggcaac atgataaccg catcaagcca cgccccaaag gatattgggc aggaaagtgg
    11281 tacaccttct gccgcgccac ccgacgctgc aacgaactgc gtcaatttgc accgtacgaa
    11341 gcactctggt atcccgtgac tctgataggg ggaacgatag ctatacaaat aaaccgatca
    11401 aaaggagtaa aagacaagaa agcaaggaca aagaaataaa agaacccgga aaataaaagg
    11461 aatgaaaaag caacagaagg acaaaaaagt gaaaaaggac agacgtgaaa aacttaggta
    11521 tattcgagag gtatctgccg aacaacgcgg acgtatcctg ctaagttgcc tcaccggcat
    11581 tctgggcgtg gcctttgccc tagcctttat ctatgcaacc aaacgggtga tagacaccgc
    11641 taccggaata acagacgaca acctgacgca tatcgccgtt ctcaccgttg tcctgctgac
    11701 tgcccaatta ctgtgcggag ctgctgacac ttggataagt acccgtatgc agatagagac
    11761 gggcaacgcc cttcgccacc gcctcttctc gcgcttactg caaagccgct ggaacgaatt
    11821 ggagcgtttc cataccggag acgtagtgaa ccgggtagaa caagacacca ccgccatcgt
    11881 cacattgctc acctcttctg tcccggcatt catcgtcacg agtatacaac tgctggcagc
    11941 ctttctattc ttctactttt tagacccttc actgccatgg ctgattgttg ccatcctgcc
    12001 cgtctttcta tcaggcagcc gtttctatat gcgacgaatg aaacgctata cacatgatat
    12061 tcggaacagt gacggtcgca tccagtccgt catacaagag agcctgcaac atcgcatagt
    12121 gattaaaaca ttggaacaag gcgaacggca tctggacaaa ctcgatgact tgcaagacat
    12181 gctccacagc caagtcatgg gacgtacccg tttctcgctt tctgcccaca tgttagtggc
    12241 ccttgccttt tccggcggat acctcacggc ttttctttgg ggagccgttc acctcagcgc
    12301 aggctgtatc accttcggaa cgatgaccgc ctttttgcaa ttggtaggaa aagtccagcg
    12361 tcccgtgttc gacctctcac gcctgatacc ttccgtagtc aatgccctta ccgccataga
    12421 ccggctattg gaattggaaa gactgccggc agaagcggat ggtgacagca tattcctcgc
    12481 ctctaccccg gaactggaac tgaaagacgt gacttttcgc tacactcccg atgaccgtcc
    12541 ggtattcagc cgcttctcct gccgtttccc cgccggtagc tgcatagcta tagtcggaga
    12601 aacaggaaaa ggaaagacaa cgctcatccg gctattgttg gcactggcaa cgccacaaga
    12661 gggacagata ctcttgatac ccgccaaaca tccacttgaa accaatcata ccgtctctcc
    12721 gcaaacccgc aagaacttcg tatatgtccc gcaaggcaat acccttttca gcggaactat
    12781 ccgtgacaac ctgctgatgg gaaaccca
//
