LOCUS       c00046_gnlPro..        13263 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDNKDNGG_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:16:26
            Original ID  :: gnl|Prokka|GDNKDNGG_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2478
            Orig. end    :: 15741
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13263
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12478:15439]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12961
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13263
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13263
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2302..3006)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MKKLRMTLAASMLLFLTAIVLQSCLDDWDDKYDTLFAVGTVKVIE
                     GKDYYFSLDEGSKLYPSDTTYVHDYAVIDGQRAFIYFRELEEKLPGYEYNAQIKHIENI
                     LTKDIYSMPAEKADSIGDDNINATDLWITGEYLNIKYQFYHSNNEDKKHMLNLVINEAS
                     TGENDKPDYVNLEFRHNAYNDSQLTLGTGLASFKLDNIAEQLKEKKGLNIRVKSLYDGE
                     RFMTIDIKKENN"
     CDS             3188..3736
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MEEQELAERCRQGDNLARKELYERYAGRMLSVCLRYAGDRETAQD
                     LMHDGFLKLFDSFDKFTWRGEGSLRAWMERVMVNTVLQYLRKNDVMNQSSALENAPEAY
                     EEPEGSSIDVIPQKVLMQFISELPAGYRTVFNLYIFEEKSHKEIARLLGINEKSSASQL
                     TRAKATLAAKVREWMKRND"
     CDS             3749..3970
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MEDELWLKKIKDKLEDYSEPLPVAGWERLEKELSVSGAPITGPHR
                     XXXXXXXXRQLCCWWRFRPSVCGCCRVR"
     CDS             3979..5058
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MRHTSVPALAVAPDVLPEQTVPAIRTNSIEPAYRAHGNASAPNKE
                     ASHPLVAQHIRISVGEEQQEEMLPVETADEAVGIGQQAEEPVVEDTDHETTMQAEEPER
                     TREDRYRPSGRDKLHLPEKNSSGRDAKGWAVGLSVGNTGGFSLANEGEANVMSGYMPGS
                     PIYGGNVDLSSTANGIVTIPDGQELVFKDGMPYLQRREKKIADIDHKQPLSFGVSVRKN
                     LAKGFSVESGLTYTYLASDVRYEGSSEKISQKLHYIGIPVRANWNFVDAKNFTMYVSAG
                     GAIEKCVYGKIGTESETVKPVQLSVMGAVGAQYNISNRVGLYVEPGVSYFFDDGSSIQT
                     IRKENPCNFTLQAGIRLTY"
     CDS             5235..7697
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 80.1; E-value: 3.4e-25)"
                     /gene_kind="other"
                     /locus_tag="ctg46_7"
                     /sec_met_domain="Fn3-like (E-value: 5.5e-26, bitscore:
                     80.1, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 3.2e-56, bitscore:
                     180.3, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 3.7e-51,
                     bitscore: 163.4, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKKKVALSGLLLCCAITAKAQVCITPQAEQRARELVSQMTLEE
                     KIDYISGPKSFYIRAVPRLGIPEIRMADGPQGIRNNTQSTLYPCGXXXXSTWNRKLARE
                     LGHGLARDAKARGVSILLGPGVNIYRSPLCGRNYEYFGEDPYLTGETAKEYILGVQEEG
                     VMATVKHFAANNQEWSRHHASSDVDERTLQEIYFPAFRKAVQEAGVGAVMDSYNPLNGV
                     HATENSWLNIDVLRKQWGFKGILMSDWTSVYSGVGAANGGLDLEMPVGKFMTREILIPA
                     IENGIVKEETIDAKVRHILQTLIAFGALDTPREDKSIDKDNAQSKEIALDLAREGVVLL
                     KNDNGTLPYRNGRTLVIGPNADIIPTGGGSGFVTPYSVVSLYDGMVQLKGGRQIELLSD
                     SILYKDMSQQIYTDGSFTQNGFKGEYYNTRNLTGELFQAAIEPAIDHAWKYGAPFDGMP
                     VDQFSARWTGVYKADKDGTVKFQLAGDDGYRLFVNDKLITGDWGNHSFSTRSAFMQVSA
                     GEIYRLRIEYFDNVGEATVSFQAGMMDEERLASSLKHARNVIVCAGFNSSTEGEGFDRP
                     FALSYGQEYLINKVASLHDNVAVVVNAGGGIDFRNWGQSVQAILMAWYPGQEGGKALAE
                     IITGKLSPSGKLPVSIEEKWEDNPVYGNYYDNRNVPHKRVQYAEGVFVGYRGYDRNGKQ
                     PLYPFGYGLSYSSFEYSNLSVEKTGGSRVTVSFDIKNTGKMDAAEAAQVYVRDVECSVP
                     RPLKELKGYDKVYLKKGETKRVRILLDEEAFAYYDVESHRFVVEKGTFEILAGPSSADL
                     PLKATVVL"
     CDS             7728..9932
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fn3-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_3_C"
                     /gene_functions="other (smcogs) SMCOG1041:Fibronectin type
                     III-like domain (Score: 87; E-value: 2.2e-27)"
                     /gene_kind="other"
                     /locus_tag="ctg46_8"
                     /sec_met_domain="Fn3-like (E-value: 3.6e-28, bitscore:
                     87.0, seeds: 729, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3 (E-value: 3.6e-75, bitscore:
                     242.6, seeds: 11, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_3_C (E-value: 6.7e-53,
                     bitscore: 169.1, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIILMVCLWGLGNTFTSAQTTEKEKFISSLMKQMTLDEKIGQ
                     LAQCTYRGNFTGPDGGNIPKEEYVRQGRIGSMLNVIGVKDIRRYQELALQSRLRIPLIF
                     GLDVIHGYRTGFPLPLAEAASFDLAMIEEAARYNALESAADGLNWVFAPMVDISWDARW
                     GRVMEGAGEDPYYGSRVAEARVRGLQGDDLADTTTVMACMKHFAGYGAPIAGKEYNSVD
                     MSMGHFANFYMPPYKAAIKVGAATVMSAFNDFNNIPCTANDFLLNRLLREQWGFKGFVV
                     SDYNSVEELVNHRYAVDKKDAAAKALNAGLDMEMVSTCYLTYLKELVQEGKVKESVLDD
                     AVRRILEKKYELGLFEDPFRYCNPERAARILNAPEVRNASLRMAERSVVLLENRESVLP
                     LTAQTRKIALIGGLSKSQYDMAGAWAATTDRSKVVTLYDALVRKGLEVNYAEGYDMKSN
                     QLTGLQEALQAAEASDVIVVAVGERFGQSGEKASKVNIAIPEGQQKLVSELAKTGKPVI
                     ALVMCGRPVIFNEIREHADAVLCTWWLGSEAGNAICNVLWGEYNPSAKLPMTFPAHVGQ
                     IPIYYQNKSTGRPTALQQTYKASYIDASTEPAYPFGYGLSYTDFGYSDLKLLPGKDAGV
                     HTEVSVKVTNTGKCAGEEVVQLYVQDKVASVTRPIKELKGFRKIHLNAGESKTVAFQIT
                     DDALGFYDNEMNYMVEPGDFVFMVGGSSDDVQQITYNLKE"
     CDS             complement(10001..10561)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="Radical_SAM (E-value: 7.7e-21, bitscore:
                     64.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISQKAFFGKKGGITFSGGEPTLQAEALIPLFKELKANGIHICL
                     DSNGGIWNEKVEELFSLTDLVLLDIKQFNPERHRTLTGRSNEQTLRTAAWLEEHEHPFW
                     LRYVLVPGYSDSEEDIRLLGESLGKYRQIQRVEILPYHRLGVHKYEVMGWDYKLKEVKE
                     NTPEQLERAEKLFKEYFTNVITN"
     CDS             complement(10733..12961)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_10"
                     /sec_met_domain="Gly_radical (E-value: 5.5e-47, bitscore:
                     148.2, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1171.1, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKTFTNGLWNKEINVSDFVSKNIAPYTGDASFLQGPTERTKR
                     IWDICLKALEEERNNNGVRSLDNTTVSTITSHKAGYIDKDNELIVGLQTDELLKRSIKP
                     FGGINVVAKACRENGVEVDDKVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRLALYGIDRLIEAKQEDLRNLTGPMTEARIRLREEVAEQIKALKDIK
                     VMGEYYGLDLSHPATSAQEAVQWVYMAYLAAIKEQDGAAMSLGNVSSFLDIFIEYDLAH
                     GKINETFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTEAIGGRFNDGRVKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKDFCAKVSVDTSSIQYENDNLMREVRNC
                     DDYGIACCVSYQAIGKQIQFFGARANLAKALLLAINGGRCENTGTVMVKGIPVLTGETL
                     KFEEVMANYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMAFIDTNPRINLAYGVAGL
                     SIAIDSLSAIKYAKVTARRNEIGLTEGFDTEGSFPCFGNNDDRVDHLGVDLVYYFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGPTPEERVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLEDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
ORIGIN
        1 ctcctcttcg gtggaagcca atattccgga gaatcccaca atggcattga gcggcgtacg
       61 gatttcatgg ctcatgttgg cgaggaatgc ggatttcagt ttattcgact cttccgcacg
      121 gttcttggcg gaaaccagtt ccgtctccat ctttttccgt tcggtgataa ccagcgaaga
      181 gcccaccagg gtcagcggct tattgttctc gtcgtaggtt tctacggcgg cctgggcctc
      241 cacccagtcg aagtgtttgt gtccgtcggc atgattgatg acgcggtatt cctccttgac
      301 tttctggata cgtccctcaa tcaggtctgt ataggcttgt ttcacttttt ccaggtcttc
      361 cttgtgtatt ttggagaaat actggctgtc gggtacggac agctgttcat cgtccatgat
      421 accggcatta ttgctgagct ctatcggctt gttgacatcg cagagtatgg tgtgtgtccg
      481 gaggttccat ttccatggta cgatgttggc aacgtcgagt gccatggaaa gtttccggtt
      541 tgtcgacctc aactgtattt gggtgtggtg caactcggtg ctgtcaacgc agaagacgtg
      601 catgtattcg ccattgtcgc ttgccttgac tacaatgtcg tagaaagtgt ctatcttctt
      661 gtaataatag gggaaagtta cggaacgttt ctccttcaat gcaatattca tgaaatggag
      721 gaactcgttc atggattcgg gaaataattc gcttccccgc ttgccgacag cctctttgcg
      781 catgataaat ctgtcttcga agaaattgtt gacatctata tataaggtgt cagtaatgcg
      841 ccctttttca tcttttataa gtttctcata catgtatagg atgggcatgt tgtttatcag
      901 atttcggtat ttgagattgc tgtccagttg ttgctgttgt aatcttttaa ttctactcag
      961 tgactgtagg cggagatatt ggaaaaagaa cagcagagtt atgattgcgg cagtgatact
     1021 gataatgaca tattcgtact tctcccagaa ggtgggaggc atgttgtaga atatggtacc
     1081 cttggggcat agcttcggat tcaggtcacg ctgcagaagg gatttatagt tgaatacggg
     1141 ggctccgtcg tcgggatagt ataacgggat gttgcgtgcc ggggtaccat ccaatatctt
     1201 gtggatggtt tctagtagcc gggcattata tttctctttg ttgtaaatgt agccgcctac
     1261 aatcccccct tcttcttcaa taccgatggc ccttagcgaa aacaaaggga tgggggcggt
     1321 agagatgacc cggtgggaat tactcctcat gatattgtca tggggagagc tcttgtacag
     1381 ccaggatgaa aagatgactc cggtagtatg gggattcacg tggttcagta tattgaaaag
     1441 gctgtccgtt cggatgtcct tcgcactaag gaactggtaa tccaactccg gatacttttc
     1501 acggataatc tcggacaagt catagtcgtt ctgctggcag atgtatgttt catcccctat
     1561 atacatgacc ttatccattt tggggatgag ttgcttcatg agttgcaggt tctcgttcag
     1621 gtatacactg gattgcatta aggtcagatt gtacttcttc tgtaggtcac tgatgggaat
     1681 acgctctgtg cggggcaggg cgtgctcgcg tatcattgtt tccttaggac cggtataatc
     1741 cctctcacca cataatatca tggggatatc gggccactgc cggttcagtt catcgcacat
     1801 gatgaaactt ccgcatccga taagcacgat aagtttaggg tttttgtaac tcttgaacaa
     1861 gctctctttg aatgtctcca gtttattttc ctcgtcaagt gtcagcattt tcatgtgtgc
     1921 ggtgtatact ccgatgtggc tgttctgtga tgccatgttc acaatggagg tgatgaaatc
     1981 attactccag ggattggctt ctgtataagt gttgattatc agaatatcgt cgacgtctgt
     2041 tgcgggagat tttccatata gggtgtctgt gcaggtgaac gagcagagta ttgcaattac
     2101 tgttcccagt atgtatttca tatcctttgg accgttttaa tgtttgctat tgtgaaaatt
     2161 cttacaaatg taggggtttc ccggtggata gacaaagaaa aagatgaatt taagcgggat
     2221 atggaaaaat aaagcggagc aacatattga aatgtcactc cgcttctcat tgagatgttg
     2281 aaagatgtgt tttcaggaga tttagttgtt ttctttttta atgtctatgg tcatgaaccg
     2341 ttcaccgtca tatagacttt tgacacggat gttcagccct tttttctctt tcagttgttc
     2401 cgctatattg tccagcttga aggaggccag tccggtgccc agcgtgagct ggctgtcatt
     2461 gtaggcattg tggcggaatt cgagattgac gtaatccggt ttgtcgtttt cgccggtgga
     2521 tgcttcattg atgaccaggt tcagcatgtg cttcttatct tcgttgttgc tgtggtagaa
     2581 ttgatatttg atgttcagat actcgcccgt aatccataaa tccgtggcgt tgatgttgtc
     2641 gtctccgata ctgtctgcct tttcggcagg catggagtag atgtctttgg tcagaatgtt
     2701 ttcgatgtgc tttatttggg cattgtattc gtagcctgga agtttctctt ccagttcgcg
     2761 gaagtagatg aaagccctct ggccgtctat tacggcatag tcgtgaacat aggttgtgtc
     2821 actgggatat agtttactgc cttcgtccag tgagaaatag tagtcttttc cttcgatgac
     2881 ctttaccgta cctacggcga acaaagtgtc atatttgtca tcccaatcgt ccaggcatga
     2941 ttgcaataca atggcagtca ggaataaaag catggatgct gccaatgtca ttctcagttt
     3001 cttcataagt ggtaggtttt agctcttttt ctatttaaaa cttatttttg tattcagaaa
     3061 atgcggtgaa aagctaaata ctgcgtagta tactgttaaa gaaatgaaag tatgattttc
     3121 ttctctgcct gatgcagtat ttttgcgccg attgcattta tagggtgaac acgtgttaaa
     3181 agagagaatg gaagaacagg aattggcaga acgctgtagg caaggagaca atcttgcccg
     3241 caaagaactg tatgagcgct atgcgggacg catgctcagc gtatgcctcc gttatgcagg
     3301 tgaccgggag actgcccaag acctgatgca tgacggtttt ctgaaacttt ttgattcttt
     3361 cgataagttc acttggcggg gagagggttc tctgcgggca tggatggaac gcgtaatggt
     3421 gaatacggtg ttgcagtatt tgcggaaaaa tgatgtgatg aatcagtcat cggccttgga
     3481 gaatgcaccc gaagcttatg aggaaccgga aggttcgtca atagatgtca ttcctcaaaa
     3541 ggtactgatg cagtttatca gtgaattgcc tgccggctat cgtaccgtat tcaacttata
     3601 tatttttgaa gagaaatccc ataaggagat tgctcgacta ttgggaatta atgaaaaatc
     3661 ctctgcctcg cagttgacgc gtgctaaagc gactttagcg gcaaaagtac gtgagtggat
     3721 gaaaagaaat gattaaatga aggaacgtat ggaagatgaa ttgtggttga aaaagataaa
     3781 ggacaagctg gaagactatt ccgaaccgct gccggttgcc ggatgggagc ggttggagaa
     3841 ggaattgtcc gtttccggag ctccgataac cggaccgcat aggannnnnn nnnnnnnnnn
     3901 nnnnnnncgg cagctgtgtt gctggtggcg gtttcgtccg tcagtctgtg gctgttgcag
     3961 agtccggtag ggaatgaaat gcggcatacg tcagtgcccg ctttggctgt ggctccggac
     4021 gtcttgccgg aacagacagt acctgccata cggactaatt ccatagagcc tgcttatcgg
     4081 gcacatggaa atgcatcggc gcccaataag gaggcaagtc accctttggt tgcacaacat
     4141 atcagaatat cggttggcga agaacagcag gaggaaatgc tgccggttga aactgcagat
     4201 gaggctgtcg gtattgggca gcaggcggaa gaaccggtag tggaagatac ggaccatgaa
     4261 actacaatgc aggcagagga accggagaga acaagggaag accgctatcg tccgtcaggc
     4321 cgggacaaac tgcatcttcc ggaaaaaaac agttctggta gggatgctaa aggatgggcg
     4381 gttggcttgt ccgtaggaaa tacgggaggt ttttcattgg cgaatgaagg ggaagcgaat
     4441 gtcatgtcgg gctacatgcc tggaagtcct atttatggcg gtaacgtaga tttatcctct
     4501 acggccaatg gtattgttac tattcccgac gggcaggaac tggtttttaa ggatggtatg
     4561 ccctatctgc aaagacgcga aaagaaaatt gcggatatag accataaaca accgctcagt
     4621 ttcggtgttt cggtgcggaa aaacttggcg aagggtttct ctgtggaaag cgggctgacg
     4681 tatacctatc ttgcttctga cgtaaggtat gagggcagct cggaaaagat aagccagaag
     4741 ctgcattata ttggcattcc ggtacgggcc aactggaact ttgtggatgc aaagaacttt
     4801 acgatgtacg tttcggcggg gggtgccatt gaaaaatgtg tgtatggcaa gattggtact
     4861 gagagtgaga ctgtgaaacc ggtacagctt tctgtcatgg gtgctgtcgg tgcccagtat
     4921 aacataagca atagggtggg cctgtatgtg gaaccgggag tatcttattt ctttgatgac
     4981 ggttcgtcga tacagactat acgcaaggag aacccgtgta actttacgtt gcaggccggt
     5041 atacgtctta cttattgata gcaggacaga catgtttttg tccactttct tgtagattca
     5101 gaattttctt aataactttc ggccgtgttt cttcgttggt ggatgaaggg acacggtttt
     5161 ttattgattg agaagaaaga aagtaggtcg ggacatgccc ggcaatataa caaacacgta
     5221 gtaaaataga caaaatgaag attaaaaaga aagtagcctt aagcgggcta ttgctttgtt
     5281 gtgcaatcac ggcaaaagca caagtgtgta ttactcccca ggcggagcag cgtgccaggg
     5341 agttggtttc tcaaatgact ctggaagaaa aaatcgatta catttccggt cccaaatctt
     5401 tttatatccg ggctgtgccc cggcttggca tacccgaaat caggatggcc gatggtccgc
     5461 aaggcatacg taacaatact caaagtaccc tgtatccttg tggtannnnn nnnnnttcga
     5521 catggaaccg taagttggct agagaactgg gacatggttt ggcccgggat gcaaaggccc
     5581 gtggggtaag tattctgttg gggcccggag tcaatatcta ccgttctcct ctatgcgggc
     5641 gaaactatga gtattttggt gaagaccctt atctgacggg cgaaacagcc aaagaatata
     5701 tcttgggagt gcaggaagag ggagtcatgg ctacggtgaa gcattttgca gccaataacc
     5761 aggagtggag caggcatcat gccagctcgg atgtggatga acgcacgttg caggaaattt
     5821 attttcccgc gttccgaaaa gctgtgcagg aagcaggagt aggagcggtc atggatagct
     5881 ataatccgct gaacggggtg catgccaccg aaaacagctg gctgaacatt gatgtattac
     5941 gcaagcagtg gggatttaaa ggtatcctga tgtctgactg gacatctgta tattccggtg
     6001 tgggagccgc taatggaggg ttggatttgg aaatgcccgt cggtaaattc atgaccaggg
     6061 agattcttat tccggcaata gagaatggta tcgtgaagga agagaccatt gacgccaaag
     6121 tccggcatat actccagaca ttgattgctt ttggagcact tgatactccg agagaagata
     6181 aatctatcga taaagacaat gcacagtcta aggaaattgc acttgacttg gcgagggaag
     6241 gagtagtgtt attgaaaaat gacaacggta cgttgcctta ccggaacggt agaacattgg
     6301 taatcgggcc taatgccgat attattccca caggaggagg aagcggattt gtcactcctt
     6361 attcggtagt gtcgctctat gacggtatgg ttcagttgaa gggcggcaga cagatagaac
     6421 tgctgtctga cagcattctt tataaggata tgtcccaaca gatttatacg gatggcagtt
     6481 ttacgcaaaa cggttttaag ggcgaatatt ataatactcg taatcttacc ggagaactct
     6541 ttcaagctgc catagagcct gccatagacc atgcctggaa atacggtgca ccgttcgacg
     6601 gcatgccggt agatcagttt tctgcccgtt ggacgggagt ttacaaggct gacaaggatg
     6661 gaactgtcaa gttccagctg gctggcgatg acggataccg tctgtttgta aacgataagc
     6721 tgattaccgg agattggggg aaccattcat tcagtacccg cagtgcattt atgcaggtca
     6781 gtgcagggga gatataccgg ttgcgtattg aatattttga taatgtgggt gaggcgactg
     6841 tcagtttcca ggcaggaatg atggatgagg agcgtttggc ctcttcactg aagcatgcca
     6901 ggaatgttat tgtatgtgcc gggttcaaca gcagtacaga aggtgaaggg ttcgaccgtc
     6961 cgtttgcatt gtcatacggg caggaatatc tcattaataa agtggcttca cttcatgata
     7021 atgtggctgt ggtggtgaat gccggaggtg gaatagattt ccgcaattgg gggcagagtg
     7081 tacaagctat tttgatggca tggtatccgg ggcaggaggg tggaaaggcc cttgccgaaa
     7141 tcattacggg caagctttcg ccaagtggca aactaccagt cagcatcgag gaaaaatggg
     7201 aagataatcc ggtatatggt aattattatg acaatcgcaa tgtacctcat aaacgggtgc
     7261 agtatgccga aggtgttttc gtaggttata ggggatatga ccggaacgga aagcagccgc
     7321 tttatccttt cgggtatgga ctgtcataca gtagttttga atatagtaat ctgagtgttg
     7381 agaagacggg gggaagccgg gttacggtaa gctttgacat caagaatacc ggaaagatgg
     7441 atgctgcgga agcggctcag gtatatgtgc gggatgtgga atgttctgtt ccgcgtccat
     7501 tgaaggagtt gaaaggctac gataaggttt acttgaagaa gggtgaaacc aagcgcgttc
     7561 ggatattgct ggatgaggaa gcctttgcct actatgatgt ggaatcacat cggtttgtag
     7621 tggaaaaggg gacttttgag attctggcag gtccttcttc agctgattta ccattgaagg
     7681 caactgttgt tttatgataa aataaatatc aaaacaagaa tggcagtatg aaaaagataa
     7741 taatactgat ggtttgtctg tggggacttg gtaacacctt tacctcggca caaactacgg
     7801 agaaggagaa attcatctca agcttgatga agcagatgac gctggatgaa aagataggcc
     7861 agcttgcaca atgcacctac cgagggaatt ttaccggacc cgacggtgga aatattccta
     7921 aagaagagta tgtccggcaa ggcagaatag gctctatgct gaatgtgata ggagtaaagg
     7981 atatacgccg ttatcaagag cttgctttgc aatcgcgttt gcgcattcct ttaattttcg
     8041 gactggatgt tatccacggc tatcgtaccg gatttccgct tccgcttgcc gaggctgcaa
     8101 gtttcgattt ggccatgatt gaggaagctg cacgctacaa tgctttggaa agtgccgccg
     8161 atggtttgaa ctgggttttt gccccgatgg tggatatttc gtgggacgca cgttggggac
     8221 gcgtcatgga aggggccggt gaggaccctt attatggttc tcgggtagcg gaggcgcgtg
     8281 tcagaggctt gcaaggagac gatttggcag acacgacgac tgtcatggca tgtatgaaac
     8341 attttgccgg atatggtgca ccgatagcag gaaaggagta taatagtgtg gatatgtcaa
     8401 tgggccactt tgccaatttt tatatgcctc cctataaggc ggccataaag gtaggagcag
     8461 ctaccgtgat gagtgctttc aatgatttta ataatattcc ttgtactgcc aatgatttct
     8521 tgctcaaccg gctattgaga gagcagtggg gatttaaggg atttgttgtg tccgattata
     8581 attcggtaga ggaattggtg aaccaccgtt atgctgttga caagaaagat gccgcagcca
     8641 aagcgctgaa tgctggtctg gacatggaga tggtaagtac ctgctacttg acttatctga
     8701 aggagcttgt tcaagaaggg aaagtaaagg agagtgtgct tgatgatgca gtacggcgta
     8761 tattggagaa gaaatatgag ttgggattgt ttgaggaccc ttttcgctac tgtaatccgg
     8821 aaagagcggc cagaatactc aatgcgcccg aagtccgtaa tgcttcgctc cgtatggccg
     8881 agcgttccgt tgtattgctg gagaataggg aatctgtgct tccgttgacg gcacagacga
     8941 ggaagatagc cttgatagga ggactctcaa aatcccaata cgatatggca ggcgcttggg
     9001 ccgccactac ggaccggagc aaagtggtga ccttgtatga tgcactggtc cggaaaggac
     9061 tggaggtgaa ctatgctgaa ggctatgata tgaagagcaa tcaattgacc ggactgcagg
     9121 aagcattgca ggctgctgag gcttcggatg tcattgttgt ggcggtaggc gagagattcg
     9181 gtcagagtgg cgagaaggct tccaaagtga atatagccat acccgagggg cagcagaagc
     9241 tggtgtcgga actggcaaag actggaaaac ctgtcattgc tcttgtcatg tgtgggcgtc
     9301 cggtaatctt caatgagata agggaacatg ctgatgcggt actgtgtact tggtggctgg
     9361 ggagtgaggc cggcaatgcc atatgcaatg tgttgtgggg agagtataat ccttcggcta
     9421 aattgcccat gacatttcct gcacacgtag ggcagattcc catttattac cagaataaga
     9481 gtaccggtcg tcctaccgca ttgcaacaga cttataaggc atcctatatc gatgcttcca
     9541 ctgagcctgc ctatcctttc ggatatgggc tttcgtatac ggattttgga tattctgatt
     9601 tgaaactgct gccgggcaag gatgcaggcg tccatacgga ggtgtcggta aaagtgacta
     9661 ataccggtaa gtgtgcagga gaggaagtag tccagttgta tgtgcaggat aaggtagcgt
     9721 ctgttacgcg cccgataaag gagttgaagg gcttcaggaa aattcatctg aatgcgggtg
     9781 aaagcaaaac tgtagctttt cagataactg acgatgcact gggattctat gacaatgaga
     9841 tgaattatat ggtagaacct ggtgatttcg tctttatggt gggtggcagt agtgatgatg
     9901 tacagcagat tacctataac ttgaaagaat aggattcttg tcctataaat gaaaagcaag
     9961 gctgtctgga atcatatccg gacagccttg cttttctgtt ttagttggtt atcacattcg
    10021 tgaaatactc tttgaacagt ttttctgccc gttccagttg ttccggagta ttttccttca
    10081 cttctttcaa tttgtaatcc catcccatga cttcgtattt gtgaacgccc agacggtggt
    10141 aaggaagtat ttccacccgt tgtatctgcc ggtatttgcc gagactttca cccagcaggc
    10201 ggatgtcttc ttccgaatcg ctgtaaccgg gaaccagtac ataacgcagc cagaaggggt
    10261 gttcatgttc ttcgagccag gcagcggtgc ggagtgtctg ttcgttgctt cgtcccgtca
    10321 gcgtacggtg gcgttcggga ttgaattgct tgatgtccag cagcacgagg tcagtcaggc
    10381 taaagagctc ttccaccttt tcattccaga tgcctccgtt actgtccaga cagatatgga
    10441 tgccgttcgc cttcagctcc ttgaaaagag gaatcagcgc ttctgcttgc agggtaggct
    10501 caccgccgga gaaagtaata cctcctttct tcccgaagaa tgccttttgg ctgatagcca
    10561 tttgcagaat ctcttccgga gtggtgggag tgcctccttt tacatcaatc gtatccggat
    10621 tggcacaata cagacaacgg aacggacatc cttgcaggaa aacgacgagc cgnnnnnnnn
    10681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nattacattc
    10741 tttcgtggaa tgaacggctg atgacttcca actgatgctc gcggctcaac ttcacgaagt
    10801 tcacggcata gccggaaacg cggatggtga gttgcggata cttttcagga tgttccatgg
    10861 catcttccag catttcgcgg ttcagtacgt ttacgttcaa atggtgggca cctttggtga
    10921 agtagccgtc catcatggtt accaggttct ctacacgttc ttccggtgtc gggcccagtg
    10981 atttaggaac aatggagaac gtattgctga tgccgtcctg cgagtcgcgg tagcgcaatt
    11041 tggctacgga gctcaaggaa gcgatggcac cgttcttgtc acgtccgtgc attgggttgg
    11101 cacccggagc aaaggcaaca cctttggcgc gtccgtccgg agtggcaccg gtcttcttgc
    11161 cgtacatcac gttggaggtg atagtcagca aggaaagggt gggacgggca ttcttgtaga
    11221 caggcagctt tttcagttct tcgctgaaat agtaaacgag gtctactccc aggtggtcca
    11281 cacggtcgtc attattgccg aagcagggga atgagccttc agtgtcgaaa ccttcggtca
    11341 ggccgatttc gttgcggcgt gcagtgactt tggcatattt gatggcggac agtgagtcta
    11401 tggcgatgga aaggccggca acaccgtatg ccagattgat gcgtgggttg gtatcgatga
    11461 atgccatctg ggccttctca taataatact tatcatgcat gtagtggatg atattcatgg
    11521 cctcgttgta gacacgggct atttcagtca gtaccttctt gtagttggcc ataacttcct
    11581 caaacttcag tgtctcgccg gtcaatacgg gaataccttt caccatgaca gttccggtgt
    11641 tttcgcaacg gccaccgttg atggcaagca gcagggcctt ggcaaggttg gcacgtgcgc
    11701 cgaagaactg gatttgcttg ccgatggctt ggtaggatac acagcaggca atgccgtaat
    11761 cgtcgcagtt gcgcacttcg cgcatcaggt tgtcgttttc gtactggatg gagctggtat
    11821 ctacggaaac tttggcgcag aaatccttga agccttccgg cagttcggga ctccacagta
    11881 cggtcaagtt tggttccgga gaaggaccga ggttgtatag cgtctgcaag aagcggaaag
    11941 aagtcttggt gactttcacg cgtccgtcat tgaagcgtcc tccgatggct tcggtcaccc
    12001 aagtcgggtc accggcaaag atatcattgt acgactgcat acgcagatgg cgtaccatgc
    12061 gcagcttgat gacgaactgg tctatcagtt cttgcgcaaa cgtctcattg atttttccgt
    12121 gagccagatc gtattcaatg aatatatcga ggaacgaaga tacgttaccc aatgacatgg
    12181 cagcaccgtc ttgctctttg atggcagcaa gatatgccat gtatacccat tgcacggcct
    12241 cttgagctga tgtagccgga tggctgaggt cgagtccgta atattcgccc ataaccttga
    12301 tgtccttcaa agctttgatt tgttccgcca cttcttcgcg tagacggatg cgtgcttcgg
    12361 tcatcgggcc ggtgaggttg cgcaagtcct cctgcttggc ttcaatcaga cggtcgatgc
    12421 cgtagagagc caatcggcgg tagtcgccga tgatacgtcc gcgggcatag ttgtcgggca
    12481 atccggtaag gaatcccagt gagcggaagg aacggatttc ttcggtatat acatcgaata
    12541 cgccgtcgtt atgtgttttg cggtaatggg tgaagatgtc ttttacttta tcgtccactt
    12601 ccactccgtt ttcacggcat gcttttgcta ccacgttgat gcctccgaaa ggtttgatgg
    12661 atcgtttcaa cagttcatca gtctgcaaac cgacaataag ttcattgtcc ttatcaatat
    12721 acccggcttt atgagaagtg atggtagata cggtggtatt gtccagtgaa cggacgccat
    12781 tgttgttcct ttcttcttcg agagccttca gacagatgtc ccagatacgt ttggtacgtt
    12841 cggtaggtcc ctgcaagaaa gatgcatccc cggtataggg tgcgatgttt ttactgacga
    12901 aatcactgac attgatttct ttattccaaa gcccattggt aaaggttttg ttcaattcca
    12961 taaaatttgt ttttgttagt aggttagata atgttatcct ttagagcgca caaaaatact
    13021 gaataaattc cgtaatttta taagagatac ttctcttttt atgttgaaca gcataaaata
    13081 actattatta ggtagtgaat gtccggggga gtagagatgt taatactttc tatatgtggt
    13141 ttatgaattg aaacaagaac cgaataataa tctgcattat ttacaaatga tgtaggttta
    13201 aggaacagtc gtattctgaa cctaattcag tcgtatagtg aatgccattc agtcgtatac
    13261 tga
//
