LOCUS       c00048_gnlPro..        15533 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDNKDNGG_48.
ACCESSION   c00048_gnlPro..
VERSION     c00048_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:16:26
            Original ID  :: gnl|Prokka|GDNKDNGG_48
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15533
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15533
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[8720:11575]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      8721..11575
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15533
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15533
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(2..337)
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MKTRIMILACLLAVPAGRMAAQQQTDPEQKATVQTQGDSIIIRKG
                     KGDMRIKVYEEQLEDGEKKEVQIYEGVYLEKVDADKRTFLDALPFIPKKRRYNAYEPHC
                     SGLYIGYS"
     CDS             complement(358..828)
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MKTSILICIRSLCLFSLLICLPAFVHAQERLQIADLFSKYGEQKD
                     VTRVELNGSILKSYRMTTYKSLVFKNVSPYRREIQQAIVHDKQDNAKKAQEVMESGVLR
                     SAYYQLKEVERNGKKLNRYIIFKIGKDSMGTLIYIEGLLSEKEMMDMLYKSE"
     CDS             complement(841..1299)
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MKIDELLDKYFEGETSCEEERELRRFFTEEEVPEHLQTYRPLFAY
                     LNREATSMAEPTEEKSVTTESAKEVPAQRKPFRLYRTFYAVSGIAAGLLLLLGVAKIIF
                     PLSGVPENYVVIDGQRYTDEKLVEAKALEALQNASFTDEDLSNLLFQH"
     CDS             complement(1296..1820)
                     /locus_tag="ctg48_4"
                     /transl_table=11
                     /translation="MELKEFKITVLPLRAKLLNYARKLTDEPEDAEDAVQEVLLKLWNK
                     RLELEQYRSIEAFAMTLTHNICIDMWRCKRNDNLSLDIVQAASPTGTPERLLEIKDEIR
                     LMHEIIHSLPNLQRTIMQMKDIEGYETDEIAEITGCGPEAIRSNLSRARKKVRDVYLRT
                     IQERKERRNEP"
     CDS             complement(1945..2502)
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MKKFRCTVCGYVYEGDAAPEKCPLCKAPASKFVEVEEATADGPLV
                     FADEHVIGVAKGCDDEMIKDLNNHFMGECTEVGMYLAMSRQADREGYPEVAEAFKRYAW
                     EEAEHASKFAELLGDCVWDTKTNLEKRMNAESGACEDKKRIATRAKALNLDAIHDTVHE
                     MAKDEARHGKGFEGLYNRYFKK"
     CDS             complement(2529..2963)
                     /locus_tag="ctg48_6"
                     /transl_table=11
                     /translation="MDVVKRLQNHNIKPSVQRIAIMNYLIEHRTHPTVDEIYTALSPSI
                     PTLSKTTVYNTLKLLSEQGAAQTLTIDERNTCYDADTSPHGHFLCKRCGKIYDLMCNNN
                     IKKVVDMDMDGHDVQEIHYYYKGICKHCIEEERLRTTKNN"
     CDS             3260..5185
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_7"
                     /sec_met_domain="CN_hydrolase (E-value: 2.4e-20, bitscore:
                     63.1, seeds: 52, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_synthase (E-value: 6.2e-33, bitscore:
                     104.1, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYGYVKVAAAVPRVKVADCKFNASEIEKEIIIADGKGVQIIAFP
                     ELCITGYTCGDLFAQQLLLEEAEMGLIQILNNTRQMDIISILGMPVALNGVLLNAAVVI
                     QKGRVLGVVPKTYLPNYKEFYEKRWFTSACDVAENSVRLCGQIIPMGRDLLFETADTTF
                     GVEICEDLWAPIPPSSTLALQGAEILFNLSADNEGIGKHNYLRSLISQQSARCIAGYVF
                     SSCGFGESTTDVVFAGNGLIYENGTLLAANERFSFEGQVVISEIDVEHLRTERRVNTTF
                     AACHANCVSALPVRISTEYVNSRDLNLTRTFEPHPFVPQGIALDERCEEVFSIQVSGLA
                     QRLVHTKAKSAVIGISGGLDSTLALLVCVKTFDKLGWSRQGIVGVTMPGFGTTDRTYTN
                     AIDLMNSLGVTVREVSIKEACIQHFKDIDHDVHVHDVVYENAQARERTQILMDIANQTW
                     GMVIGTGDLSELALGWATYNGDHMSMYGVNASVPKTLVKHLVKWVAEHDMDDASRATLL
                     DIVDTPISPELIPADENGNIQQITEDLVGPYELHDFFLYYFLRCGFRPSKIFFLAARTF
                     KGMYDEETIKKWLQTFCRRFFNQQFKRSCLPDGPKVGSISLSPRGDWRMPSDASSEMWL
                     REVEGL"
     CDS             complement(5414..6244)
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MTKSRLLKYALLGIAAALIAHYLIKKEEKPKGHPRDYAEITAEGI
                     IHASTEYNSISFYVDDDTLSGFHYKLIEAFARDHGLQAAISPEMSFNKRLEGLADGQYD
                     VIAYGILATSELKDSLLLTTPIVLNKQVLVQRKLENISDSSLFIKSQLDLAGKTLHVVK
                     GSPSILRIRNLGNEIGDTIYVEEIEKYGSEQLIALVAHGDIDYAVCDESIARTAADSIP
                     QIDINTAISFTQFYSWGVSKQSPILLDSLNTWLDSFKKGKEYKKIYKRYYGKRN"
     CDS             complement(6256..8466)
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MRRIVLTYIFLSVIGIWGAMAQNTLNPMNNRDRFGNQIDPNTQPD
                     NLEDSTNTEIQSLPPKLYMWKLSETLGNRTIIPADTASLNFQSTNLVEGMFGHYNYLGN
                     LGSPRLSRLFFEREESEPTIFMAPFSSFFTRPDQVLFTNSNVPYTNLTYYKAGNKVNGE
                     ERFKSYFSVNVNKQLAFGFNIDYLYGRGYYQNQSTSHFNAGLFGSYIGEKYQVQAVYNN
                     FFLKMNENGGIADDQYITRPENMSGGKKEYESTTIPVKLEQSSNRNKDFYIYLTQRYRL
                     GFTRRVRNTQEGKPTVSAPKASSSPSSESEISASNNDIALPNDSIASKSVSTLAAANDS
                     LPSVSTADNDSLFEEEFVPVTSFIHTLKVERSRHQFRSGSEPEGFFPEDYKLYKNYSND
                     STTAFSVKNVFGIALLEGFNKYAKAGLTAYISHKFSRYDLMNTDTLTDMRRIRYTEQEI
                     FVGGELAKREGKLLHYNVNGEVGLVDKAIGQFRVNANLDLNFRLWKDTVNFYARGYVSN
                     TLPSFYMRHYHSNHYNWDNDNMDKEFRTRVEGELNISHWGTNLRAGVENIKNYTYFNQS
                     ALPEQNGGNIQVLSATLKQDFRLGVFHLDNEVTWQKTSNETVLPLPQLSLYHNFYILAK
                     LAKKVLTVQLGADVRYFTKYNAPAYAPGVQQFHLQPTDDLVEIGGYPIVNVYANLHLKR
                     TRIFAMMYHVNAGMGSANSFLVPHYPINPRLFKIGVSWNFYD"
     CDS             complement(8721..9266)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_10"
                     /sec_met_domain="POR (E-value: 1.5e-36, bitscore: 116.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVTWMPAYGPEQRG
                     GTANVTVIVSDEKISSPILSKYDAAIILNQPSLEKFESKVKPGGVLIYDGYGIINPPTR
                     KDIHVYRINAMDAANEMNNAKAFNMIVLGGLLKIKPMVTLDSVLRGLKKTLPERHHHLI
                     PMNEEAIKKGMELIQEMK"
     CDS             complement(9289..10050)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_11"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-26, bitscore:
                     83.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEDIIKPENLVAKKPTLMNDNPMHYCPGCSHGVVHKLVAEVIE
                     EMGLEDKAIGISPVGCAVFIYNYIDIDWQEAAHGRAPALATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKTSTSPYGRDVHLH
                     GYPLKMADIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMAGKGSNLVEIVSTC
                     NSGWKMSPAKSNEWMVENMFPFYPLGDLKDK"
     CDS             complement(10062..10235)
                     /locus_tag="ctg48_12"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMVLALAAIIIYFAAKDDFKLFIYVCGAAIFV
                     KLMEFFIRFTNR"
     CDS             complement(10232..11122)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_13"
                     /sec_met_domain="PFOR_II (E-value: 4.7e-29, bitscore: 91.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.1e-31, bitscore: 98.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVYGGAGSGKMVMTSSSSPGVSLKQEGISYLAGAELPCLIVNVMR
                     GGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVGLAFELAFKYRNPAI
                     ILADGVIGQMMEKVVLPVQKPRRTDAEVIEQCPWATTGRTNGRKPNVITSLELKPEEME
                     KNNIRFQAKYKQIEENEVRFEEIHCDDADYLIVAFGSMARIGQKAMELAREEGIKVGML
                     RPITLWPFPTKAIAAYADKVKGMLVTELNAGQMVEDVRLAVNGKVKVEHFGRLGGIVPD
                     PDEIVDALKEKLIKK"
     CDS             complement(11348..11575)
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_14"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-13, bitscore: 41.2,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.2e-09, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.9e-09, bitscore: 25.9,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-06, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLNVIALTKEVNVKGYNYAH
                     QILEDTCNGCASCATVCPDGCISVYKIKVE"
     CDS             complement(11592..11867)
                     /locus_tag="ctg48_15"
                     /transl_table=11
                     /translation="MERLNTIKELINQGNVEQAIQQLDEILQTDFPGKDEAYYLRGNAY
                     RKQGNWQQALNNYQYAIDLNPESPAQHAYQMAMDILNFYNKDMYNQ"
     CDS             complement(12043..12480)
                     /locus_tag="ctg48_16"
                     /transl_table=11
                     /translation="MKTIGICSDHAGFELKEYVRGWLEAKGWAYKDFGTYSTESCDYPD
                     FAHPLALAVEAGECYPGIAICGSGEGISITLNKHQGIRAALCWTAEIAHLARQHNDANV
                     LVMPGRFISTEEADMIMREFFSTPFEGGRHQRRVDKIPVHL"
     CDS             complement(12572..14581)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transket_pyr"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_17"
                     /sec_met_domain="Transket_pyr (E-value: 1.6e-35, bitscore:
                     112.7, seeds: 81, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_N (E-value: 1.3e-94,
                     bitscore: 307.0, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDNKLMNRAADNIRILAASMVEKANSGHPGGAMGGADFVNVLFS
                     EFLVYDPENPAWEGRDRFFLDPGHMSPMLYSTLALTGKFTLDELKEFRQWGSPTPGHPE
                     RDIMRGIENTSGPLGQGHTFAVGAAIAAKFMKARFEEVMPQTIYAYISDGGIQEEISQG
                     SGRIAGALGLDNLIMFYDANDIQLSTETKDVTIEDTGKKYEAWGWKVIKINGNDPDAIR
                     GALNEAKAEKECPTLIIGHTVMGKGARKADGSSYEADCATHGAPLGGDAYINTIKNLGG
                     DPTNPFVIFPEVAELYAKRATELKKIMAEKYAAKAAWAKANPEKAAKLEMFFSGKAPEV
                     NWAAIEQKAGVATRAASATVLSALATQVENMIVASADLSNSDKTDGFLKKTHAFKKGDF
                     SGAFFQAGVAELTMACCCIGMALHGGVIPACGTFFVFSDYMKPAVRMAALMEVPVKFIW
                     THDAFRVGEDGPTHEPVEQEAQIRLMEKLKNHKGHNSMLVLRPADAEETTVAWKLAMEN
                     TTTPTGLIFSRQNIANLPEGNDYEQAAKGAYIVAGSDENPNIILVASGSEVATLVAGTE
                     LLRKDGIKVRIVSVPSEGLFRSQAPGYQEGIIPCGAKVFGLTAGLPVTLQGLVGPRGKV
                     WGLESFGFSAPYKVLDEKLGFTAENVYKQVKAML"
     CDS             complement(14772..15533)
                     /locus_tag="ctg48_18"
                     /transl_table=11
                     /translation="TVSGWNGSKGAATRFSKDDYYWTLGKCREIEDVIKKHCTIMDKYD
                     PQKNVALMLDEWGTWWDTEPGTNPGHLYQQNTLRDAFVASLSFDIFHKYTDRLKMANIA
                     QIVNVLQSMILTSGKNMVLTPTYYVFKMYNVHQDATYIPLELNCDMMDVRDNRRIPMVS
                     ATASKDPNGKIHISMSNVDADNAQEVTINLSGTKAKKAVGEILTSTNLTDYNSFENPDN
                     VKPVPFKEVKINKDILKIKLPAKSIVTIELQ"
ORIGIN
        1 ggctgtagcc aatatacaga ccggaacagt gcggttcgta agcattgtat cttctctttt
       61 tggggatgaa tggcagtgcg tcgaggaaag tgcgcttgtc tgcatccact ttctcgagat
      121 agactccttc ataaatttgt acttctttct tttctccgtc ttccaactgc tcttcgtaca
      181 ccttgatgcg catgtctcct tttcctttcc ggatgatgat ggagtcgcct tgtgtctgta
      241 ctgtagcttt ctgttcaggg tcagtctgtt gttgtgctgc catgcggccg gccggcacag
      301 caagcaggca ggccaaaatc ataattctgg ttttcatatc gtatattgtt tttagtgtta
      361 ttccgatttg taaagcatat ccatcatttc cttttcactg agcagaccct ctatgtaaat
      421 caaagtgccc atggagtctt ttcctatctt gaaaatgatg tagcggttca gcttctttcc
      481 attgcgttcc acctctttca gttggtaata agcgctacgc agcacaccgc tttccattac
      541 ctcctgcgcc ttctttgcgt tatcttgctt gtcgtgtaca atggcctgct gaatttcccg
      601 gcgatagggg gatacattct tgaacacaag gctcttgtag gtagtcatgc ggtaagattt
      661 caggatactg ccgttcagtt ctaccctggt cacgtccttt tgctcgccat acttgctgaa
      721 taggtcggct atttgcagtc tctcttgtgc atgtacaaag gctggcaggc aaatcagcag
      781 ggaaaagagg cacagactac gtatgcaaat cagtatagat gttttcataa ccttgttata
      841 ttagtgttga aacagtaagt tgcttaaatc ttcatccgtg aagctggcgt tctgcagggc
      901 ttctagtgct ttggcttcca ccagtttctc gtctgtatac cgctggccgt cgatgacgac
      961 ataattttcg ggaacaccgg aaagcggaaa tataatctta gctaccccga gaagcaggag
     1021 caatccggcg gcaatgccgc tgacagcata gaatgtgcga tagagacgga aaggcttccg
     1081 ctgtgcgggt acttcctttg ccgattctgt tgttacggat ttttcctctg tcggttctgc
     1141 cattgaagtt gcttcccggt tcagataagc gaataggggg cggtacgttt gcaggtgctc
     1201 cggcacttcc tcttcggtaa agaaacggcg cagttcacgc tcttcttcgc aggaagtttc
     1261 cccttcgaaa tatttatcca gcagttcatc tatcttcatg gctcatttct cctttctttt
     1321 ctttcttgta tggttcgcag gtaaacgtct ctcactttct tccgggctct tgacagattg
     1381 ctgcggatgg cttccggtcc gcatcccgtg atttcggcga tttcgtccgt ttcgtatcct
     1441 tcgatgtctt tcatctgcat gatggtgcgt tgaagattgg gcagcgagtg gatgatttcg
     1501 tgcatcaagc ggatttcatc tttgatttcc aacagccgtt ccggtgttcc ggtgggggat
     1561 gccgcctgca caatgtcaag agataggttg tcgttgcgtt tgcagcgcca catatctata
     1621 cagatgttgt gcgtcaacgt catggcaaat gcttcgatgc tccggtattg ctccagttca
     1681 agccttttgt tccatagctt gagcagtacc tcctggacgg catcttctgc atcctccggt
     1741 tcgtcggtca acttccgtgc atagttcaac agcttggcac ggagtggaag aacggttatt
     1801 ttgaattctt tgagttccat ttacacagat aagacgaatg ggaaatacaa acgtgacatt
     1861 gtaaagtgaa aaaagttgga ataaaaaaag ggacttacta acattagcag tcccttttct
     1921 tcacattact ataaaagtat aggattattt cttgaaatag cggttgtaca gaccttcgaa
     1981 acctttaccg tgacgggctt cgtccttagc catttcgtga acggtgtcat ggatagcgtc
     2041 gaggttcaat gctttggcac gggtagcgat acgcttcttg tcttcgcatg cacctgattc
     2101 tgcgttcatt ctcttttcga ggtttgtctt ggtgtcccat acgcagtcgc ccagcagttc
     2161 ggcaaacttg gaagcgtgtt ctgcttcttc ccaagcgtaa cgcttgaaag cttctgcaac
     2221 ttcgggataa ccttcacggt ctgcctggcg gctcattgcc aagtacatac caacttctgt
     2281 acattcgccc atgaagtggt tgtttaggtc cttaatcatt tcgtcgtcgc aacctttggc
     2341 tacgccgatt acgtgttcgt cggcaaatac cagcgggccg tcagctgttg cttcttcaac
     2401 ttctacgaac ttgcttgcgg gagctttaca caatgggcac ttttcgggag ctgcatctcc
     2461 ttcgtatacg taaccgcata cagtacatct aaattttttc attttctctc agattttaat
     2521 tagttgaatt agttattctt tgttgttctt aaacgttctt cttctatgca atgtttacag
     2581 attcctttat aatagtagtg gatttcctgc acatcgtgcc cgtccatatc catgtcgacc
     2641 actttcttga tgttgttatt gcacatcaag tcataaatct ttccgcaacg cttgcacaag
     2701 aaatgaccgt gcgggctggt atcggcatca taacatgtgt tacgctcgtc gatagtcagg
     2761 gtttgtgcgg caccttgctc gctcagtagt ttcaaggtat tgtataccgt tgttttagac
     2821 agtgtcggta tggagggaga cagtgccgta tagatttcat ccaccgtggg atgcgtacga
     2881 tgctctatca agtaattcat gatggctatg cgctgtactg aaggcttgat attatgattc
     2941 tgcaatcgtt ttactacatc catataatct aaagtttcaa acttgtaatt attacatttt
     3001 taattcactt gcaaagatag gaagttccta taattctcca aaagattttt ggaaaatttt
     3061 tagttgcggt cattaaaatt gtttatatat gttcctcttc ttgtaggtag gttgccgtat
     3121 ttttgtcata aaagcgaagg caggatgcac ccggttttag tcagtttctc gtgccgatat
     3181 agataaaacg tttttccctt atctctctta atcagaattt tgccgtatct ttgcaccgaa
     3241 taaataatat agcatcctta tgaattacgg atatgtaaaa gtagcggcgg ctgtgccccg
     3301 tgtcaaggtg gctgactgta agttcaatgc ctcagagatt gaaaaagaga ttattatagc
     3361 cgatgggaaa ggtgtgcaaa tcattgcttt tccggagttg tgcattaccg gatatacttg
     3421 tggcgacctc tttgcccagc aacttctgct cgaagaggcg gaaatggggc tgatacagat
     3481 tctgaacaat acgcgccaga tggatatcat ttcgatattg ggcatgcccg ttgcactgaa
     3541 cggtgtgttg ctgaatgcgg cggttgtcat tcagaagggg agagtgctgg gcgttgtccc
     3601 gaagacttat cttcccaatt ataaggagtt ttatgagaag cgctggttta cttccgcatg
     3661 tgatgtggca gaaaacagtg tgcgcctttg cgggcagatt attccgatgg ggagagacct
     3721 gctgttcgaa acggcagata ccactttcgg agtggagata tgcgaagatt tgtgggcacc
     3781 cataccgccc agttccacgc tggcactgca aggtgcggaa atcttgttca atctttcggc
     3841 cgacaatgaa ggtatcggca agcacaatta tctgcgctcg cttatcagcc agcagtcggc
     3901 acggtgcatt gccggttatg tattcagctc atgcggtttc ggagaatcca ctacggatgt
     3961 ggtgtttgcc ggcaacggac tgatttatga gaacgggact ctgctggcgg caaacgaacg
     4021 cttctctttc gaagggcagg tggtcatcag tgaaattgat gtggaacact tgcgtacgga
     4081 gcgccgggtg aatacgacct tcgcggcttg ccatgcaaat tgtgtttcgg cccttccggt
     4141 acgaatctct acggagtatg tcaacagcag ggatttgaac ctgacacgta cttttgaacc
     4201 gcatccattt gttccgcagg ggatagcgtt ggacgaacgc tgtgaggagg tattctccat
     4261 ccaggtgtcc ggactggcgc aacgtctggt gcatactaaa gcgaagagtg ccgttatcgg
     4321 catttcgggt ggactggatt ctacgctggc gctgctggtt tgcgtaaaga ctttcgataa
     4381 gttgggatgg tcccgccagg gtattgtcgg tgtcaccatg ccgggattcg gaacgaccga
     4441 ccgtacttac acgaatgcca tcgacctgat gaactccctc ggtgtgactg tccgcgaagt
     4501 cagtatcaag gaggcctgca tacagcattt caaagacata gaccatgatg tccatgtgca
     4561 cgacgtggtt tacgagaatg cgcaggcacg ggagcgtacc caaatcttga tggatattgc
     4621 caaccagacc tggggaatgg ttatcggtac gggcgacctt tcggaacttg ctttaggatg
     4681 ggccacttac aacggcgatc acatgtcgat gtacggtgtg aatgccagcg tccccaagac
     4741 tctggtgaag cacttggtga aatgggtggc agagcatgat atggacgatg cttcacgtgc
     4801 taccttgctc gatattgtgg atactcccat cagcccggaa ctgattccgg cagatgagaa
     4861 cggtaatatc cagcagatta ccgaggattt ggtggggccg tatgagcttc acgacttctt
     4921 cctttattac ttcctgcgct gcggtttccg tccttccaag atatttttcc tggcagcacg
     4981 gacattcaag gggatgtatg atgaagaaac catcaaaaaa tggttgcaga ctttctgccg
     5041 tcgtttcttc aaccagcagt tcaagcgttc ctgtttgccg gatggtccga aggtgggcag
     5101 tatctctctg agtccgcgcg gtgattggag aatgccgagc gatgcttcgt cggagatgtg
     5161 gctaagggag gtggaaggac tctaattctt tacttcgggt atgccgtaat atcgatatgg
     5221 gtatttgatg actgcatctt gtttgcattc ttgctgcatg tattttgcag tgcgactgca
     5281 aacgtgttgc agtatcactg caacggcttt gcagtggcac tgcaaaatgt atgcaggatt
     5341 ttgcagtaat aagctgctga ttgataacta gttgtaaaag tagggatatg ctgcgtgtat
     5401 ggaaaagtgc agcttagttt cgtttcccgt agtatcgttt gtagattttc ttgtattctt
     5461 ttcccttttt gaaactatcc agccatgtgt tgaggctgtc cagcaggata ggggactgtt
     5521 tgcttacccc ccaggaatag aattgcgtga agctgatggc ggtattgatg tctatttgag
     5581 gaatgctgtc ggctgcggta cgggcaatgc tttcgtcgca tacggcatag tcgatgtctc
     5641 catgggctac caaggcaatc agttgttcgg aaccgtactt ctctatttcc tcaacgtaga
     5701 tggtgtcgcc tatctcattt cccaggttgc ggatgcgtag tatggaaggg gagcctttca
     5761 ctacgtgcag tgtctttcca gccaggtcca gttggctttt gatgaataat gacgagtcgg
     5821 aaatattctc aagcttgcgt tgcaccagca cttgcttgtt cagcacaata ggggtggtaa
     5881 gcagcaagga gtctttcagc tcactggtgg cgaggatgcc gtaggcaatc acgtcatatt
     5941 gcccgtcggc caggccttcc agccgcttgt tgaagctcat ttccggtgat atggccgctt
     6001 gcagcccgtg gtcgcgtgca aaagcttcta tcagcttgta gtggaaaccg gacaaggtgt
     6061 catcatccac atagaaactg atggagttgt attccgtcga agcatgtatg atgccttcgg
     6121 cagttatctc ggcataatcg cgcggatgac ctttcggttt ctcttctttc ttgatgagat
     6181 agtgggcaat gagagccgct gcaattccca gaagtgcgta tttgagcagt ctgcttttcg
     6241 tcatacagtc atctgttagt catagaaatt ccatgagacg ccaattttga acaagcgcgg
     6301 attgatgggg tagtgcggca ccaggaagga attggcgctt cccatacccg cgttgacgtg
     6361 atacatcatg gcaaagatac gcgtccgctt caagtgcagg ttagcatata cgtttacgat
     6421 ggggtaaccg cctatttcca ccaaatcgtc cgtaggttgc agatggaatt gctggacgcc
     6481 gggtgcatag gcgggtgcgt tgtacttggt gaagtaacgg acatcggcac ccaactgaac
     6541 ggtcagcacc ttcttggcga gtttagccaa tatgtagaag ttatggtaga gcgagagttg
     6601 gggcagtgga agtactgttt cattgctcgt cttctgccag gtcacctcgt tgtccaggtg
     6661 gaagacaccg aggcggaagt cttgtttcag cgtggcagac agcacttgta tgttgcctcc
     6721 gttctgttcg ggcagggcgc tttggttgaa gtaagtgtag ttctttatat tctctacacc
     6781 ggcacggaga ttggttcccc aatgggaaat gttcagctcg ccttccacac gcgtacggaa
     6841 ttctttgtcc atgttgtcat tgtcccagtt gtagtggttg gagtgataat gacgcatata
     6901 gaaggaagga agcgtgttgc tcacataacc gcgggcgtag aagttcaccg tatctttcca
     6961 tagacggaag ttcaggtcca gattggcgtt gacgcggaac tgcccgatgg ctttgtctac
     7021 caaccccact tcaccgttta cgttgtagtg caacagtttg ccttcgcgct tggcgagctc
     7081 gccgcccacg aagatttcct gttcggtgta gcggatgcgg cgcatgtcgg taagcgtgtc
     7141 cgtgttcatc aggtcgtacc ggctgaactt gtgggagata taagccgtaa gtccggcttt
     7201 ggcatatttg ttgaaacctt ccagcaaggc tattccgaac acgttcttta cactgaatgc
     7261 cgtggtggag tcgttgctgt aattcttgta aagcttgtag tcttccggga agaatccttc
     7321 gggctcgctt cccgaacgga attggtgccg cgaccgctct actttcaagg tatggataaa
     7381 gctggtgacg gggacgaact cttcttcgaa aagtgagtcg ttgtctgcgg tagaaacaga
     7441 cggcaggctg tcattggcag ctgcaagtgt gctgaccgat tttgatgcta tgctgtcgtt
     7501 tggcaatgct atgtcgttgt tcgaagcgga tatttcggat tcagaggacg gggaggatga
     7561 ggctttgggt gcggataccg tcggtttgcc ttcttgtgtg ttccgtactc tccgcgtaaa
     7621 accaagacga tagcgctgtg tcagatagat ataaaaatcc ttgttacggt tggaactctg
     7681 ttccaatttg accggaatag tggtggactc gtactctttc tttcctccgg acatgttttc
     7741 gggacgggtg atgtattggt cgtctgcaat accgccgttc tcgttcatct tcaggaaaaa
     7801 gttgttgtag actgcttgta cctggtattt ctcgccgata tagctaccga acagtcctgc
     7861 attgaagtgc gaggtggact ggttctggta ataaccgcgc ccgtacagat agtcgatgtt
     7921 gaagccaaat gccaactgct tgttgacgtt gacggagaaa taggacttga agcgttcttc
     7981 accgttcact ttgttgccgg ccttgtagta ggtaagattg gtgtaaggca cgttgctgtt
     8041 ggtgaaaagc acctggtcgg gacgtgtgaa aaaactggag aagggagcca tgaagatggt
     8101 aggttcgctt tcctcccgtt cgaagaacag acgtgagaga cgtggagaac ctaaatttcc
     8161 caagtagttg tagtggccga acattccttc caccagattg gtgctctgga agttgaggct
     8221 ggctgtgtcg gcaggtatga tggtacggtt gcccagtgtc tcacttagtt tccacatgta
     8281 aagcttgggt ggaagacttt gaatctcagt attggtactg tcttccagat tgtccggctg
     8341 ggtattcggg tcaatctggt taccgaaccg gtcgcgattg ttcatcgggt ttaaggtgtt
     8401 ttgcgccata gccccccata tccctataac ggacagaaat atatatgtca gtacaattcg
     8461 tctcataatt aggcgcaaag atacaataaa aaattatttg cttactgaat tcagcctttt
     8521 ttgcttcttt taaactgtct tgttttctgt tttgttctat actgcttccg gttctctgcc
     8581 cttgaatcca tactttttcc ggcttgaaat gaaataagcc cttgcaataa atcaatatca
     8641 caagggctta tccgttttcc tttatctctt attctggcgt aaagttcctc ctcttatggg
     8701 gagtggcttt acatagcctt tcatttcatt tcctgaataa gttccattcc tttcttgata
     8761 gcttcttcgt tcatcggtat caagtggtgg tggcgttcgg gcagtgtctt cttcaatcct
     8821 ctgagtacac tgtccagtgt aaccatcggc ttgattttca ataatccacc caatacaatc
     8881 atgttgaatg ccttggcgtt gttcatttca ttggcggcat ccatggcgtt gatgcggtaa
     8941 acgtggatgt ccttacgcgt cggcgggttg atgatgccgt aaccgtcgta gataagtacg
     9001 cctccgggtt ttaccttgct ttcgaatttc tccagtgacg gctggttcag gatgatggcg
     9061 gcatcgtact tgcttaagat gggtgaggat attttctcgt cacttacgat gactgttacg
     9121 ttggctgtac caccacgttg ttccggtccg taagccggca tccaagtcac ctctttgcct
     9181 tccatcaatc cggaatatgc caaaatcttt cccatggaca atacaccttg tccaccgaag
     9241 cctgctataa tgatttcttc tttcattgtt cttctgtctt tagcatgatt atttatcttt
     9301 caggtcgccc agcggataga aggggaacat gttctctacc atccattcat tggatttcgc
     9361 aggagacatc ttccagccgg agttacaggt ggaaacgatt tccacaaggt tggaaccttt
     9421 gcctgccata gagttctcga atgctttgcg gatagccttt ttcgctttgc ggatggcggg
     9481 aacggactgt acgctttggc gtgtcacgta agcggttcct tccaattgtg cagcaatatc
     9541 ggccatcttc agcggatagc cgtgcagatg cacgtcacgt ccgtaagggc tggtcgatgt
     9601 cttcatgcct acaagggtag tgggagccat ttgtcccccg gtcataccat agatggcatt
     9661 gttgatgaag atgatggtga tgttttcgcc gcggttcaag gcgtggatgg tttcggcagt
     9721 accgatacaa gccaggtcgc cgtctccttg gtaagtgaac accaggcggt ctggccaaag
     9781 gcgcttgatg gcagtggcaa gtgcgggcgc acgtccatgg gcggcttcct gccagtcgat
     9841 gtctatataa ttatagatga acacggcaca tcccacaggg gagatgccta ttgctttgtc
     9901 ttccagtccc atttcttcga taacttcggc tacgagttta tgaactacgc cgtgactgca
     9961 tcccgggcag tagtgcatgg gattgtcgtt catcagagtc ggtttcttgg caaccagatt
    10021 ctcgggcttt ataatatctt cttttgtcat aatcacttct cctatctgtt ggtgaaccgt
    10081 atgaaaaact ccatcaactt gacgaatatc gccgcgccgc agacgtagat gaacagcttg
    10141 aagtcatctt ttgcagcaaa atatataatg atagctgcca aggcaagtac catgaagaga
    10201 atgttcagta cgtttcttat tttatcagga ttcatttctt aatcagtttt tctttcaatg
    10261 catctactat ctcatccgga tcgggaacaa tgccgccgag gcgtccgaaa tgttccactt
    10321 tcactttacc gttcacggca aggcggacat cttccaccat ctgtccggca ttcaattctg
    10381 taacgagcat acctttcacc ttgtcggcat acgcggcaat ggctttggtc gggaacggcc
    10441 acaacgtgat ggggcggagc atacctacct tgattccttc ttcgcgtgcc agctccattg
    10501 ctttctgtcc gatgcgtgcc atagagccga aggctacaat caggtagtcg gcatcatcgc
    10561 aatgaatttc ctcgaagcga acctcattct cttctatctg cttgtatttg gcctggaaac
    10621 ggatgttgtt cttttccatt tcttccggtt tcagttccaa tgaggtgatg acgttgggtt
    10681 tgcggccatt ggttctgccg gtagtggccc atgggcattg ttcgatgact tccgcatcgg
    10741 tgcggcgtgg cttttgtacc gggagcacca ctttttccat catctggccg atgacaccgt
    10801 cggcaaggat gattgccgga ttacggtatt tgaaggcaag ttcgaatgcc agtcctacga
    10861 aatctgccat ttcttgtacg gaagccggag caagggcaat cagacgatag tcaccgtggc
    10921 cgcctccttt tactgtctgg aaatagtcgg cctggctcgg ttggatggtt cccagaccgg
    10981 gaccgccgcg cataacgttt acaatcaagc aaggcagctc ggcacctgcc agataagaga
    11041 taccttcctg ctttaggctg acaccggggc tggaggagga ggtcatgacc attttaccac
    11101 ttccggcacc gccgtacacc atattgatag ctgccacttc actttctgcc tgaagaacca
    11161 ccatgccggt cgtnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11281 nnnnnnnnnn nnnnnnnnnn nnnncattaa tacaacttct tctgccatat tctactgatt
    11341 tacagattta ttctactttt attttatata ctgagataca tccgtccgga catactgtgg
    11401 cgcacgaggc gcagccgtta caagtatctt ccaatatctg gtgggcatag ttataccctt
    11461 tcacattcac ctccttggtg agggctatta cgttgagcgg acacgctacc acacacaagt
    11521 tgcagccttt gcaacgttcg gtgtctacta cgattgctcc tttgattttt gccataattt
    11581 acgttcttta tttattgatt gtacatatcc ttgttgtaga agttcaggat gtccatagcc
    11641 atttgatagg catgttgtgc cgggctttcg gggttcaggt cgatggcata ctgatagttg
    11701 ttcagtgctt gttgccagtt gccttgtttc cgataggcat ttccccgcag gtagtaagct
    11761 tcgtctttgc cgggaaagtc tgtttgcagt atttcgtcaa gctgctggat ggcttgctct
    11821 acatttccct ggttgataag ctcttttatg gtattcagtc gttccatatc taaaaaatat
    11881 ccgggttatc gaaccacaaa gatagttttt atttgaagac aatgagcatc ttcactgtga
    11941 aaaataagaa aaaggggcaa ataaaaagcc cgaagtttct cacgattcta tcagaatgtc
    12001 agagcttcgg gcggatatca taaagaaggt gattctattg ctttacaagt gtaccggtat
    12061 cttgtccact cttcgttggt ggcgtccgcc ttcgaatggt gtactgaaga attccctcat
    12121 aatcatgtcg gcttcttcgg tactgatgaa tcgccctggc atgacaagca cattggcatc
    12181 attgtgctgg cgtgccaaat gggctatttc tgccgtccag cagagggctg cgcggatacc
    12241 ctgatgcttg ttcagcgtta tgctgatacc ttcaccgctt ccgcagatgg caattcccgg
    12301 atagcactct ccggcttcca cggccagtgc caaaggatgt gcaaagtcgg gatagtcgca
    12361 actctcggtt gagtaggtcc cgaagtcctt gtaagcccag cctttggctt ccaaccagcc
    12421 gcgaacatat tccttcaatt cgaagcctgc atggtcggaa cagattccta ttgttttcat
    12481 gatggtcagt taatatacca atgtgccaat gtgctgatgc ctgcagcttg tagggcgcgg
    12541 gcaatcagca catcagcaca ttggataatg attataacat tgcttttact tgtttgtaaa
    12601 cgttctctgc ggtgaaaccg agcttttcgt ccagcacttt ataaggtgcc gagaatccga
    12661 atgattccaa tccccatact ttaccgcggg gacctaccag cccttgcagt gtgacgggca
    12721 gaccggctgt caggccgaat accttggcac cacacgggat aatgccttct tgatatcccg
    12781 gagcttggct acggaacaga ccttcggaag gaacggacac gatacgcacc ttgatgccat
    12841 ccttgcgcag caattcagta ccggctacca atgtggcaac ttccgagcct gaagcaacga
    12901 ggattatatt tggattttca tcggagccgg ctacaatata agcgcctttg gcagcttgtt
    12961 cgtaatcgtt gccttcgggc aggttggcga tgttctggcg ggagaaaatc aaaccggttg
    13021 gggttgtggt attttccatt gccagtttcc atgccacagt tgtttcttct gcatctgccg
    13081 ggcggagtac caacatggaa ttatgtccct tgtggttttt cagtttttcc atcaggcgga
    13141 tttgggcttc ctgctctacc ggttcatggg taggaccgtc ttcacctaca cggaaggcat
    13201 cgtgtgtcca gatgaacttc acgggaactt ccatcagggc tgccatacgt acggcaggtt
    13261 tcatgtagtc ggagaatacg aagaaagttc cgcaagcggg gattacaccg ccatgcagtg
    13321 ccataccgat acagcaacat gccatagtca gctcggcaac accggcctgg aagaatgcac
    13381 cgctgaagtc acctttcttg aaggcatgtg ttttcttgag gaatccgtct gtcttgtcgg
    13441 aattggaaag gtcggcagaa gcaacaatca tattttctac ttgagtggcg agagcactga
    13501 gcacagtggc agatgctgcg cgggtggcaa cgcctgcttt ctgttcgatg gcggcccaat
    13561 tcacttcggg agccttgccg gagaaaaaca tttccagttt ggcagccttt tctggattgg
    13621 cttttgccca tgcggctttg gctgcatact tttcagccat gattttcttc agctcagttg
    13681 cacgcttggc atatagttcg gccacttcgg ggaagatgac aaacggattt gtcgggtcac
    13741 cacccaaatt cttgatagtg tttatataag cgtcgccgcc cagaggagca ccgtgcgtgg
    13801 cacaatcagc ctcgtagctg ctgccgtctg ccttgcgggc acctttaccc attacggtat
    13861 ggccgataat cagcgtcgga cactctttct cagctttggc ttcgttcagt gcaccgcgga
    13921 tggcatcggg atcgttacca ttgattttaa tgactttcca gccccaagct tcgtatttct
    13981 tgccggtatc ttcgatggtc acatcctttg tctcggtaga aagctgaatg tcgttggcat
    14041 catagaacat gatgagatta tccaacccta atgctccggc gatacggcct gagccttggg
    14101 agatttcttc ctggatgcca ccgtcagaaa tataagcgta gatggtctgt ggcattactt
    14161 cttcgaaacg tgccttcatg aacttggctg cgatggctgc accgactgca aatgtgtgtc
    14221 cctggccgag cggtccggaa gtgttttcga tgccgcgcat gatgtcacgt tcgggatgtc
    14281 ccggagtagg gcttccccat tggcggaact ctttcagttc gtccagcgtg aacttgccgg
    14341 tcagggccaa tgtagagtaa agcatcggtg acatgtgtcc cgggtcgagg aagaaacggt
    14401 cacgaccttc ccaagccgga ttttcagggt catataccag gaactctgag aagagtacat
    14461 ttacaaagtc agcaccaccc atggcaccgc ccggatgccc ggagttggct ttctcaacca
    14521 tggatgcagc aaggatacgg atattgtccg ccgcacggtt cataagtttg ttgtcgttca
    14581 tattgaatct aattaatttt gaatattatc aataggttat ttggtccttg taggttttcc
    14641 aagggcaaag ataactcttt atgcgtaatt cacaacactc gaagagtgtc ttttttatca
    14701 gtattactgc ctttttgctg ctaaaatgat actaaacgta tttagctgat tttgtgcggt
    14761 gcacggtagt tttactgtaa ctcaatagta acgattgatt tggccggaag tttaatcttg
    14821 agaatatctt tattgatttt tacctctttg aacggaacgg gtttcacatt gtcgggattt
    14881 tcaaatgaat tgtagtccgt cagattggtg gaagtcaata tttcaccaac tgctttcttg
    14941 gctttcgttc cagacagatt gatggtcact tcctgtgcat tgtctgcatc tacgttggac
    15001 atggaaatgt gtatcttgcc gtttgggtct ttggaggcgg tagcgctgac cattggtatt
    15061 ctgcggttgt cgcgtacatc catcatgtcg cagttcagct caagaggaat gtaggtggca
    15121 tcctggtgta cattgtacat tttgaataca taataagtgg gggtgagtac catgtttttt
    15181 ccgctggtca gaatcatgga ttgcaataca ttgacgattt gggcaatgtt tgccattttc
    15241 agacggtcgg tatatttatg gaagatgtcg aagctgaggg aggcgacaaa agcatcacgc
    15301 aatgtattct gctggtacag atgtccggga ttggtacccg gttcagtgtc ccaccaggtt
    15361 ccccattcgt caagcataag agctacgttc ttttgagggt cgtatttatc cataatggtg
    15421 caatgcttct tgatgacatc ttctatttcg cggcatttgc ccagtgtcca gtaataatcg
    15481 tctttactga atcgggtggc ggcgccttta ctgccgttcc atccgctgac ggt
//
