LOCUS       c00012_gnlPro..        13718 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFFMJECB_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 06:28:36
            Original ID  :: gnl|Prokka|PFFMJECB_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2404
            Orig. end    :: 16122
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13718
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12404:16010](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13606
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13718
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13718
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(88..1389)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cys_Met_Meta_PP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_3"
                     /sec_met_domain="Cys_Met_Meta_PP (E-value: 3.3e-137,
                     bitscore: 446.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRMMNQELRPETLCVQAGWAPKKGEPRVLPIYQSTTFKYETSEQ
                     MAKLFDLEEAGFFYTRLQNPTNEAVARKIAELEGGVAAILTSSGQAASFFAIFNICEAG
                     DHIVSASAIYGGTYNLFAVTFRKMGIEVTFVDQDAPAEEIAKAFRPNTKAFFAETISNP
                     TLCVLDIRKMADIAHAHGVPLIVDNTFATPINCRPFEWGADIVTHSTTKYMDGHAAAVG
                     GVIVDSGKFDWEAHKDKFPGLTEPDPSYHGLSYSKSFGKGAYITKATVQLMRDLGSIQS
                     PQNAFLLNLGLETLHLRVPRHCENAQKVAEFLQGQEDVAWINYPGLSSNKYYELAQKQF
                     RGGQSCGVVTFGIKGGRERSIKFMDSLKLAAIVTHVADSRTCVLHPASHTHRQLTDEQL
                     MEAGVRPDLIRFSVGTEAAEDIIADLKQALEAIR"
     CDS             complement(1638..2885)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_4"
                     /sec_met_domain="Radical_SAM (E-value: 7.5e-28, bitscore:
                     87.8, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINITRLWTGAEQPADHLRYGQGHGHGRFAGGAVESCAPASSRAR
                     KPIVVWNITRTCNLKCVHCYADASARKFKGELDWDQCCAVIDDLADYKVNALLFSGGEP
                     LVHPRFMELLERATGKGLKVTISTNGTRITPEAAARFKELGVAYVGISLDGIGAVHDKF
                     RGVEGSFEQAVRGFRLCSEVGQKTGLRLTLTRNNVQCMGQILDFIDANDIQRVCFYHLV
                     PTGRGVEVQTLTQEEARNAMDTLIARVEEWKAEGKNREVLTVTQPADGIYLLLRQLREG
                     SPLAKETLGLLQWNGGGANSSGRGIANIDTQGAVHPDQFWQSVTLGNVKSDRFSDLWDA
                     RAGAAAEMLPELRGSDDPLERQKKIEGRCGRCVHFALCGGGFRTRAAFANGHWYGSDPG
                     CYLTEEEISTPLPEIK"
     CDS             complement(2878..3939)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_5"
                     /sec_met_domain="Radical_SAM (E-value: 2e-23, bitscore:
                     73.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPVFSETDLNERPFLVFWEVTRACALACRHCRAVAQPRPHPDEL
                     THEEALRLIDQLAELRPPMLVLTGGDPVMRPDILELVRAASGKGLHVALSPAATARLLH
                     TDFHALKEAGVQSMSLSLDGAHESTHDAFRGVPHTYERTLRAAEMAKEAGMHLQINTTI
                     TKSTLGEFDDFVELVKKMKPGMWSVFLLVPTGRAAMDEMPAAEEVEAVWKKLSRISHEV
                     SFGVKTTEGHHYRRVALQEARAQGSKPARRAIPTRDGKGIMFISHTGEIQPSGFLPITA
                     GNVRTDDPGEIYRTHPLFLKLRDDNALQGKCGRCEYRTICGGSRSRAYAVYGDMMAEDN
                     LCPYQPRLSQHHD"
     CDS             complement(4011..4829)
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MNKIVASISLGTAVCITASAFAQDSHLSLTRQSVASMHEIAAALD
                     KVTDEPGAAAAVETVKKVHKKLLDIGKRQLELPGATLQEQAQVSAQITEAQKISGELIK
                     SLSRLKKEGLLTPDLQKALADLQSVQKELAQASRDKAEQAEPFPEDAEGNTHETLLTKT
                     VEEVKKLNGSLARVRDEETGKAAVEQIGRYRAAMLDVARKQAALPPLTRNQQAKLMGVQ
                     QQLVEMMQPIVKHVTAIMLSPDASRNLKEALNSLSELPKEVQKIREKAAK"
     CDS             complement(4970..5404)
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MKRAIISALFAAGVVGVASADIQAPPASEYTPTRKLGRAIANLIY
                     SVEEIPLGIINWTSREGDYAGFSVGIVDGTATMFERMGYGIYELVTFWAPTYKCTYKPP
                     YQGRCGMSGLKEYNPNGGLSEFPAELSFQSYYKYSRQQRD"
     CDS             complement(5462..6469)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_8"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 1.2e-43,
                     bitscore: 138.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLASNIHPTCDLGQVKDAELIVVVVPSVAMRSVAQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASLIGFEDPKYA
                     DWVQQIFASKTFRVYSATDIIGMQLGGTIKNVFAIGAGLCEGLNLGDNAQAALLTRGLA
                     EMTRIGVASGGRRETFMGLSGVGDLIVTCYSRHSRNQTVGRRLAEGKSLQEILDTLGMV
                     AEGVPNTLSVYEIARKLEVRTPLIDAVYSVLYESKPPMEALAELMTRDPRPELD"
     CDS             complement(6474..7118)
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             complement(7371..8156)
                     /locus_tag="ctg12_10"
                     /transl_table=11
                     /translation="MAPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALAAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADCLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             complement(8174..9655)
                     /locus_tag="ctg12_11"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWKRADYQDLIRGVAGEDWFDIS
                     PEARRDRCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             complement(9702..9938)
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MSGAKGKSNYAYVGLCRPFFNNKTSFVSIPLDIVLYVVLSKLFAK
                     RPEYWGMFRHPASEKGGEGTFGSKPAAKNVPSA"
     CDS             10001..13606
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_13"
                     /sec_met_domain="PFOR_II (E-value: 4.4e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4e-76, bitscore: 245.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.2e-32, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-11, bitscore:
                     32.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 7.9e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 8.5e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.2e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAAXXXADFAAI
                     SHAATLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPV
                     LRGTAQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVI
                     ILMGSGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTK
                     EPGSQGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNL
                     ALDTPKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKII
                     GQHTNLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDF
                     LKNAANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRIN
                     MIMQTCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTT
                     GKTVNGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNL
                     ALDLPEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKF
                     VIQISPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDR
                     TKVRTDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGN
                     LPTTPWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELV
                     DRILANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAY
                     DIGYGGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATNGKPGVKKDLG
                     LMAMTYGNVYVAXXXVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAK
                     GLQQQKAWVDSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTN
                     KEGFEKLLEEAQKDVWHRWNLYQSIAGMGADKPAE"
ORIGIN
        1 acaatccgct gtccccttta tccaatcttt aatgataaag aaaaagccgc ctcagcaaag
       61 tgaggcggct ttttccaaga agacttttta acgaatagct tccaaagcct gtttgaggtc
      121 cgcaataatg tcttccgcag cttccgtccc tacggaaaac cggatgaggt caggccgtac
      181 gcccgcctcc atgagctgct catccgtcaa ctggcggtgc gtatggctgg cgggatggag
      241 aacgcaggta cgggaatccg ccacatgggt cacgatggcg gccagcttca gactgtccat
      301 gaacttgatg gaacgttcac ggcctccctt aatgccgaag gttaccacac cacaagattg
      361 gccaccgcgg aattgcttct gcgccaattc ataatactta ttggaagaaa gccccggata
      421 attaatccag gcaacatctt cctgcccttg caggaattcc gccactttct gcgcattttc
      481 acaatgccgc ggcacacgca ggtggagggt ttccaaaccc aagttgagca aaaaggcatt
      541 ctgcggagac tggatggaac ccagatctcg catgagctgg acggtcgcct tggtaatata
      601 ggctcccttg ccgaagcttt tgctgtagga gagcccgtga taggaggggt ccggttccgt
      661 cagacccggg aatttatcct tgtgcgcttc ccagtcaaac ttgccgctgt ccacaatcac
      721 gccgcccacg gcggcggcat ggccgtccat gtacttggtg gtggagtggg tgacgatatc
      781 cgcaccccat tcaaaaggac ggcaattaat gggtgtggca aaggtattgt ccacaatgag
      841 gggaacgccg tgcgcatggg caatatccgc cattttacgg atatccagca cgcaaagcgt
      901 gggattggaa atagtctccg caaagaaagc tttcgtattg gggcggaacg ctttggcgat
      961 ttcctccgcc ggagcgtcct ggtccacgaa agtaacttca atgcccattt tccggaatgt
     1021 gacggcaaag aggttgtatg tgcccccgta aatcgccgaa gcactgacga tatgatcccc
     1081 agcctcgcaa atattgaaaa tggcaaagaa ggaagccgcc tggccggaag acgtcagaat
     1141 ggcggccaca ccgccctcca gttcggcaat ttttctggca accgcctcat tggtggggtt
     1201 ctggaggcgt gtataaaaga atccggcttc ttccagatca aacaattttg ccatttgttc
     1261 gctggtctcg tacttgaacg tcgtgctctg gtaaatgggc aatacgcggg gttcgccctt
     1321 tttaggcgcc cagcccgcct gcacgcacag ggtctccggt ctcaattcct gattcatcat
     1381 gcggggcatg ctatgcgatg ccacctgcct tgtaaagcag ggaaaaccag acgtatggac
     1441 aaattcgccc ctgccccgcc gaagcacgct tccgggtttt tcccaatgta aaaccccctg
     1501 ttcccggcaa atcaaccgca aggacagggg cgttttacct gcgcgcggga taccctacga
     1561 tcgaatgaaa cggcaattcc tccgataccc ctttcccgga accaaccgtt ccccggtgaa
     1621 taaagccggg catctcacta cttgatttcc ggcaaggggg tggaaatttc ctcttccgtc
     1681 agatagcagc cgggatcgga cccgtaccag tgtccgttgg caaatgcggc acgggtgcgg
     1741 aagcctccgc cgcacagggc gaagtgaacg cagcggccgc aacggccttc aatcttcttc
     1801 tgccgttcca gaggatcgtc ggaaccgcgc agctcaggca acatttccgc tgcagctccg
     1861 gccctggcat cccataaatc ggaaaaccgg tcacttttca cattgcctag agtaacggat
     1921 tgccagaact ggtccggatg cacggcaccc tgtgtgtcaa tattggcgat gccccggccg
     1981 gaactgttcg cgccgccgcc attccattga agcaggccga gggtttcctt cgccagaggg
     2041 gagccttccc ggagctggcg cagaagcagg taaattccgt ccgcaggctg ggttacagtc
     2101 agcacttcac ggttttttcc ctccgctttc cattcctcca cacgggcaat cagcgtatcc
     2161 atggcattcc ttgcttcctc ctgagtcagg gtctgcactt ccacgccgcg gccagtgggg
     2221 accagatggt aaaaacagac gcgctggatg tcgttggcgt caataaaatc caaaatctgg
     2281 cccatgcact gcacattgtt gcgggtcagc gtcaggcgca ggcctgtctt ttgccccact
     2341 tcactgcaaa gcctgaatcc gcgcaccgcc tgctcaaaag aaccttccac accgcggaat
     2401 ttgtcatgaa cggcgccaat gccgtccagg gaaatgccta cgtacgccac gcccaattcc
     2461 ttgaaccgcg ctgcagcttc cggcgtaata cgggtgccgt ttgtggaaat ggtcaccttc
     2521 agcccttttc cggtggcacg ttccagcaat tccataaagc gcggatgcac cagcggctcc
     2581 cctccggaaa aaaggagggc attcaccttg tagtccgcca gatcatcaat gaccgcgcaa
     2641 cactggtccc aatccagctc tcccttaaat ttccgggcag aggcgtctgc ataacaatgc
     2701 acgcatttaa gattgcaggt acgcgtaata ttccacacca caatgggctt gcgcgcacgg
     2761 gacgaagccg gtgcacagga ttccacggcg ccccctgcaa aacgaccgtg cccgtggccc
     2821 tgtccgtatc tcaaatggtc cgcgggctgt tccgcccctg tccaaagtct ggtaatatta
     2881 atcatggtgt tgtgaaagcc tgggctgata agggcaaagg ttgtcttccg ccatcatgtc
     2941 tccgtaaacg gcataagcgc gagaccggga ccctccgcag atggtacggt actcacaccg
     3001 tccgcatttg ccctgcaacg cattgtcatc ccggagtttg aggaaaaggg ggtgcgtgcg
     3061 gtagatttct ccagggtcat ccgtccggac gtttcctgcc gttatgggga gaaaaccgga
     3121 gggctgtatt tccccggtat gagaaataaa cataatgccc ttgccgtccc gggtgggaat
     3181 ggcgcggcga gcaggcttgc ttccctgagc acgggcttcc tgaagcgcca cgcggcgata
     3241 atggtgccct tccgtcgttt tgacgccgaa agaaacctca tggcttatcc tgctcagttt
     3301 tttccagacg gcttccactt cttccgccgc aggcatctca tccatggcgg cgcggcctgt
     3361 gggcaccaga agaaacacgc tccacatgcc cggtttcatt tttttcacca gctccacaaa
     3421 gtcgtcaaat tctcccagcg tgcttttggt aatggtggtg ttgatttgca agtgcatgcc
     3481 ggcttccttc gccatttccg cagcccggag agtccgttca tatgtgtggg ggacaccgcg
     3541 gaaggcgtca tgggtacttt catgcgcacc gtccaggctc aatgacatgc tctgaacccc
     3601 agcttctttc aacgcatgga aatccgtgtg caacagccgg gcggtagcag cagggctcaa
     3661 tgccacatgc agccccttgc cggaagccgc acggaccaat tccagaatat ccggcctcat
     3721 gaccgggtct ccgcctgtca gcaccagcat gggaggccgc agttccgcca actggtcaat
     3781 caggcgcaat gcctcctcat gagtcaattc atccgggtgg ggacgcggct gggcgacggc
     3841 gcggcaatgt ctgcacgcaa gcgcgcaagc gcgcgtcact tcccagaaga ccaggaaagg
     3901 gcgttcattg agatctgttt cgctaaaaac cgggcgcatt tttcaggaca gccaatttag
     3961 aacaattata attttttaac cagcccaaaa ggacgcatcc tttaaaaagt tcacttagcc
     4021 gccttttcac ggattttttg aacttcctta ggcagttcgg aaagggaatt cagagcttcc
     4081 ttcaggttcc tggaagcatc cggagaaagc atgatggccg ttacatgctt gacaatgggc
     4141 tgcatcattt ccacaagctg ctgctgcact cccatcagct tggcctgctg gttgcgggtg
     4201 agaggcggca gggcagcctg tttcctggca acgtccagca tagccgcccg gtagcgacct
     4261 atctgttcca cagcagcctt gccggtttct tcatccctta ccctggccag agagccgtta
     4321 agctttttta cttcctccac agttttggtt agcagggttt catgcgtgtt gccctccgca
     4381 tcctccggga acggctccgc ctgctcagcc ttatcccggg aagcctgcgc cagctccttc
     4441 tgaacagact gtaaatccgc tagggctttt tgcaaatcag gcgtaagcag accttccttc
     4501 ttcaaacggg acagagattt tatcaattca cctgaaattt tctgtgcttc cgttatctgg
     4561 gcggaaacct gagcctgctc ctgaagcgtg gcaccaggaa gctccagctg tcttttccca
     4621 atgtccagca gctttttatg aactttttta accgtttcca cagcagcggc cgctccaggt
     4681 tcatccgtta ccttgtccag agccgctgcg atttcatgca tgctggcaac gctctgcctg
     4741 gtcagggaaa gatgggagtc ctgggcaaat gcggaggctg ttatgcaaac ggcagtgccc
     4801 aggctgatgg aagcaacaat tttattcatg atacggaagc ctttccggta tggaagaata
     4861 cgttttcctc ctttccccgt caatggcggc tattgtcaag accactatat gaaaaaaggg
     4921 ctgtccgcaa acaagcggac agcccttttg aaatcttaac agcccggcct tagtcgcgct
     4981 gctggcgtga atacttgtag tagctctgga agctgagttc cgcagggaat tcgctcaggc
     5041 cgccattggg attgtattcc ttgaggccgc tcatgccgca gcgcccctga taagggggct
     5101 tgtacgtgca tttgtaagtg ggagcccaga aggtgacaag ttcataaatt ccgtagccca
     5161 tgcgttcaaa catggtagcg gtgccatcaa caatgcctac ggaaaaaccg gcataatctc
     5221 cctcgcggct cgtccagttg atgattccca gcgggatttc ttcaacggaa taaataaggt
     5281 tggcgatggc gcggcccagc ttgcgggtgg gggtgtattc ggaagcgggg ggagcctgaa
     5341 tgtccgcact ggcgacacca acgacgccgg cggcaaaaag agctgagatg atggcacgtt
     5401 tcatactgat tgtttatata gtataatttg tcgagggaaa gcaactcaaa aaaacaaaaa
     5461 atcaatctaa ttccggccgg gggtcccgcg tcatgagttc cgcaagcgct tccatcggcg
     5521 gcttggattc ataaagaacg gaataaacgg cgtcaatcag gggcgtcctc acctccagct
     5581 tccgcgcaat ttcatagacg gacaacgtgt tgggcacccc ttccgccacc atgcccaggg
     5641 tatccaggat ttcctggagg ctcttccctt ccgccagtct ccgccccacc gtctggttgc
     5701 gggagtggcg ggaatagcag gtaacaatca aatcgcctac tccggaaagg cccatgaagg
     5761 tttccctgcg gcctccgctg gccacgccga tgcgcgtcat ttccgccagg ccgcgggtca
     5821 gcaaagcggc ctgggcgtta tcccccaggt tcagcccttc gcataagccg gccccgatgg
     5881 caaagacgtt cttaatggtt ccgcccagct gcatgccgat aatgtccgta gcggaataaa
     5941 cacggaaggt tttggatgca aatatctgct gcacccaatc cgcatacttc ggatcttcaa
     6001 atccaatcag ggaagcggac ggaaggccca ggcagatatc ttccgcatga ttgggaccgg
     6061 aaagcacgcc tatggggttg gagggcagat attcctgaag gatttccgtc attcttttat
     6121 gggttccctg ttcaatgccc ttggtgcagg agacgatgac ggcatccggc tgcaccggca
     6181 ggctgcgcag ccgctgggcc acggaacgca tggctacgga aggcaccact actacaatga
     6241 gttccgcatc cttcacctgg cccaggtcgc aagtaggatg gatattggag gccaggggaa
     6301 gggcggtttt cgaaaggacg gggctgcgcc ttgtttcggc aagctgcctg gcctgagcct
     6361 cttccggcgt ccacaggacg acttcacatt cccgggtcgc cagaaccatg gagagggccg
     6421 tgccccagga accggctcca atgactgcta ttttatgtaa ccgattcatc atcttacttg
     6481 gactttttgg aatagaagga gtgctccgtt ccgttgagaa gccttgcgat attggaacgg
     6541 tgcttgagaa tcaccagcgc gcctaccacc gtgaaaaagg cgacgtaaag tatctggggg
     6601 gagacatccc cgtcctggca aagcggataa atccaccatc cggcggcgat catcaccaca
     6661 gcggccacca ggctggccag ggaaacgatg ccggagattc ccataaccac cagccaagaa
     6721 gccagagcta cgcaagccac caccggattg agggcaaata aaacccccgc ggttgtcgct
     6781 acgccttttc ctcccctgaa tcccaggaaa caagtgtaag tatgaccgag tataacagcg
     6841 aaacaggaga gaactaccaa gacattgaaa tcccagccgc ccgcatcccc cgtcaggaac
     6901 ggcagccagt tcaaggcgcc gaacacaggg atgaacccct ttaagaagtc cagaatgaaa
     6961 acggaaaggc cccacttcca gcccagtacg cgccacgcat tggtagcgcc tatgttgcgg
     7021 gaaccctgct gcctcaggtc aatccctctg attctgccgg caaggtagcc gaacggaatc
     7081 gctccgatca ggtaatagaa aactatccag gcaatcatgt tgtgcggagt gcattttaat
     7141 cccccgccgg tcaaatgaca atggggaaat cacctctggc ccggttcttt ccggaggggt
     7201 tgctcctgta aaagaacacc atgcctgaca gcctcctcca gatcctcatt ttcaaggctc
     7261 tccgtgcccc ggtctgcgga aaagccctgt ttaaggcgca ataagaacag cgcgaacatt
     7321 ttcccgcccg cccagaacca tgctcccgca cttccttcgc cggaataagc ttatttaccg
     7381 ccctcgcagg gtttccgcat gacggcagcc cagacggagg cattatcctg ctggggctcc
     7441 agcatatcct tcacctgttc cataatgatc cccaccagct ccctgctgga acaatccctg
     7501 gccttttgaa gagccaggaa agaaggttct ctcaacagct cgctccaaac ctgcaagccg
     7561 tccgagcatg ccagcaccgc atctcccgga tgcaggagca ggggcatggc gctgatgtcc
     7621 accagttcca tgggaccgcc cataacggcg gaacggagaa tgcaacgctg ccgaagcgca
     7681 ccctgaagtg acattttccc cttccggtaa aggcaatccg caatcggtct catggaatgg
     7741 tcttcattca gacggtccat gcgaaagctg tccgctccgc tccataaata caggggggag
     7801 tctcccacgc tgatccacca caggaaatgg tcgcggatga agacggccag caatgtggtt
     7861 ccggattcct ccggttcctt ctgaatggcg gccaacgccc tgttggcagc atgcaaagcc
     7921 gccgttaaac gttccgggat atcctcgatg ccgctttccg caaataccgc ggcaaattcc
     7981 tgcgccacca cacaggaggc gcaatctccg cgaagatgcc ctcccatgcc gtcgcacacg
     8041 atgcctagca tcccgccagc ggcgggaaga cttttaacca cgtcttcctg ctcgcggcgt
     8101 ttgccgatcc attgggcgga agcgcagtcc agaatatccg gggtgcgggg agccatgcgg
     8161 ccggtggttc ggattaactg tccttacgtt tcaactgcgg gaagagcagc acgtcacgga
     8221 tggaagaagc ccccgtcagc atcatgacga cgcggtcgat gccgatgccg atgccgcctg
     8281 cggagggcat tccgtattcc agcgtttcaa tgaaatcata gtccacacgc tgggtctccc
     8341 cggcagcctg gtgctccagg cgttcctttt gcacgtcagg atcgttcaat tccgaatagc
     8401 cgggggaaat ttcctgcccg ttgatcacca gttcatatac atccactacg tccggatttt
     8461 cccggttcag cttggccagg ggaaccaggt ccttggccac gtgggtaaca aagcaggggt
     8521 tcatggtctt ttcctccacc agtttttcat acacctgctg ggaaacatcc acatctttca
     8581 tatccgggct gatttccact cccagctctt cacagcggtc gcggcgcgct tcgggggaaa
     8641 tgtcaaacca gtcttccccc gccacgcccc ggatcaggtc ctggtagtcg gcgcgtttcc
     8701 agggacggct gaggtcgatt gtgtaaagaa cgttgccttc agcgtccttg tggtcaatct
     8761 gaaggccgcc gcagaatttt tccgccagat ggcagatgag ctcctccacc atattcgcca
     8821 tggtttcaaa atcaccgcag gcgcaatagg cttccagcat ggtgaattcc gggttgtggc
     8881 ggcggtcaat tccttcattg cggaagctgc ggttgagttc gaaaattttc gtgaagccgc
     8941 ccaccatcag gcgtttgagg aaaagctccg gggcaatgcg cagcgtcagc ggcatatcaa
     9001 gcgcgttatg gtacgtttca aacggcttgg cggcggcccc accggccaca tcctgaagca
     9061 tgggggtttc cacttccaga taaccgcgtt cctggagaaa gcggcggatt tccgcaatca
     9121 tgagggagcg cgtaacgaac agggaggcgc tttcctcatt ggaaatgagg tccaggtggc
     9181 gcttgcggta ggtcacctcc ttgtccgcca gtccgtgcca cttgtccggc agggggcgga
     9241 ggcttttgga aagaatggtc agtccggata cctttacggt aggttctccg gtacgggtca
     9301 ggaacgtggt tcccctgatg ccgacccagt ccccgcggtc caggagcttc caaagcttcc
     9361 aggtggtttc atccacctca tttttatgca ggaacccctg gatttttccc cgtacgtccc
     9421 caatgacgaa aaactgggat ttgcccatgt cgcgaatagc cagaaggcgg ccggcgacgg
     9481 ctacctgttt gtcttcctgg aaatcggctt tcaatccggc gggagtggtg gtcacgtcaa
     9541 atcttgcgcc gtaagggtca attcccagct cacggatttt ggcgagcttg tcgcggcgca
     9601 cggcaataag ttcggattcc gtcgtggtcg gatgtgcctg ctgttgttcg gacatagtgc
     9661 ggggattcta aaggcttgct tccgttttgg ctagcgcatt gtcaggcaga ggggacattt
     9721 ttggcggccg gttttgaccc gaaggttcct tccccccctt tttcggaagc cggatgccgg
     9781 aacattcccc agtactccgg ccgttttgca aaaagcttgg acagaaccac ataaagcacg
     9841 atatccaaag gaattgaaac aaaactggtc ttattattaa aaaatggccg gcaaagcccc
     9901 acatacgcat aattgctttt acctttggca ccagacatgt tataaatgtt cccgttaaga
     9961 cgcaccttat ttatcaatta tatactatcc gtgcagactt atgagtgatc agacaaccgt
    10021 aacttacagc acgattgacg ctaacgaagc cgtagcctcc gtagcctatc gtttttctga
    10081 agtcattgcc atttacccca ttacaccatc ttctccgatg ggtgaatcag ctgaaagctg
    10141 ggccgctgtc aacaggaaga acctgtgggg caccgttccc tccgtggtgg aaatgcagag
    10201 tgaaggcggc gcggcaggca ccgttcacgg cgccctccag accggagcgc ttgcaactac
    10261 gttcactgca tcccaggggc tcctgctgat gatcccgaac atgttcaaaa tcgcagggga
    10321 actgactccc gccgtgttcc acgtagccgc ccggtccctg gcttaccagg ccctttccat
    10381 ttttggcgac cacagcgacg tgatgagcgc ccgctcctgc ggatgggcca tgctgtgcgg
    10441 ctcctccact caggaagctg cnnnnnnnnn ngcggacttc gccgctattt cccacgccgc
    10501 tacactggaa tcccgcattc ctttcattaa tttctttgac gggttccgca cgtcccatga
    10561 aatcggcaag attgcagaca tcacggacga taccctgaac ggcatgatta agcaggaatg
    10621 gctggattcc ttccgggaac gagccctgac ccctgatgct cccgttctgc gcggcactgc
    10681 ccagaacccg gacgtttatt tccagggacg tgaaacggtc aaccgtttct atgaagccac
    10741 tccggctatt gtccagaacg ccatggacaa attcgcggaa cttaccggcc gttcctacca
    10801 tctggtggat tacaccggcg ctccggacgc cgaacgcgtc attatcctga tgggatccgg
    10861 cgctgaagct gtggaagaaa cggtagaagc catgatgacc cgggaaaacg ccaaggttgg
    10921 cgtgctgaag gtgcgcctgt tccgcccatt ccccgccgcc gaactcgtca aggccctccc
    10981 cgctacggtc aggaagatcg ccgtgctgga ccgcaccaag gaacccggct cccagggaga
    11041 accgctccac caggacatca tccaggccct cttcgacgcc caggccaacg gcacgctgcc
    11101 cttcaccaac ggcatgccca aggtggtagg cggacgctac ggcctctcct ccaaggaatt
    11161 cacccccgcc atggtcaagg gcgtctatga caacctggct ctggacactc ccaagaatca
    11221 tttcaccatc ggcatcaacg acgacgtact gggcaccagc ctcccgtatg atgaagatta
    11281 ttccacggaa gcggacgacg tgacgcgggc catgttcttc ggcctcggtt ccgacggcac
    11341 cgtaggcgcc aataaggacg ccatcaagat catcggccag catacgaacc tgtatgtgca
    11401 gggctacttc gtgtatgact ccaagaaatc gggttcctcc accatttccc acctgcgctt
    11461 cggtccccgt ccgatcaaat ccacatacct gatcaccaag gcaaacttcc tggccctgca
    11521 ccagccttcc ctgctggatc tgttcgactt cctgaagaat gccgccaacg gcgccacttt
    11581 cctgatgaac agcccgcacc cggcggacaa gctctgggac acgctgcccg cccgcatgca
    11641 gcagcagatt ctggacaaga acatcaagct ctacacgatt gacgcttttg ccgtggcccg
    11701 caaaacgggc atgggcggcc gcatcaatat gattatgcag acctgcttct tcaagctggc
    11761 cagcgtgatt cccgcggatg aagccatcgg ctacatcaag aaggccattg ccaaaaccta
    11821 cgccaagaag ggccaggaag tggtggacaa aaacatcgcc gccgtggacg ccacgctgga
    11881 aaacctgcac caggtggaca caaccggaaa aactgtaaac ggacacgcca ttccgcccgc
    11941 catgtccccg gacgctccgg actacgtaca aaacgtcctt ggcaagatga tgtgcggtga
    12001 aggcgacagc atcccggtca gccaaatgcc cgtggacggc acattcccga acggaacgtc
    12061 ccagtacgaa aagcgcaatc tggccctgga tctgccggaa tgggatccga ccctctgcat
    12121 ccagtgcggc aagtgtaccg ccgtctgccc gcatgcggtt atccgcagca aattcttctc
    12181 tcctgacgct cttgcaaacg ctccggaagg gtttgaatgc ctggatgcca agcatccgga
    12241 ctggaaggga gagaaattcg tcatccagat ttccccgaac gactgtacgg gctgtacgct
    12301 ctgcgcggac gtctgcccgg ccaagagcaa gacggacccg acacacaagg ccctgaccat
    12361 ggtcccggcc gggaagattc atgacaagga agaagccaat tggaatttct tcctgagcct
    12421 tccggacgtg gaccgcacca aggtaagaac ggacaacatc cgctccatgc aggtgctgcg
    12481 cccgctgttc gaattctccg gcgcctgtgc cggctgcggt gaaactccgt atgtaaaaat
    12541 gctctcccag ctcttcggca accgcctggt ggtcgccaat gctacgggct gctcctccat
    12601 ttacggcggc aacctgccca ccaccccgtg gtcccatgac tctgaagggc gcggccccgc
    12661 ctgggccaac tccctgtttg aagacaacgc cgaattcggc cttggcttcc gcgtctccct
    12721 ggacaagcag atggaacacg ccattgagct tcttcatgaa gctgccggcg ccgtgggcca
    12781 ggaactggtg gaccggatac tggctaatcc gcagaaggat gaagcagaca tcgcccagca
    12841 gcgtgaaaac attgaagaac tcaagaagaa aattgccggc aagccggaat acgcgcgcct
    12901 cctgaccctt gcggataaac ttgtccgcaa gagcgtgtgg attctgggcg gcgacggctg
    12961 ggcctacgac atcggctacg gcggcctgga tcacattctg gccagcggcc ggaacgtgaa
    13021 ggtgctggtc atggatacgg aagtatactc caacaccggc ggccagtgct ccaaatccac
    13081 cccgcgcgcc gcagtagcca aattcgccac gaacggcaaa cccggcgtga agaaggatct
    13141 gggcctcatg gccatgactt acggcaacgt gtacgtggcn nnnnnnnnng tggcctccgt
    13201 cgctctcggc gccaaggacg aacacacgct gaaagccttt gtggaagcgg aagcctatga
    13261 cggcccggct ctcatcatcg cctactccca ctgcatctcc cacggcatca atatggccaa
    13321 gggcctgcag cagcagaagg catgggtgga ttccggccga gtcctgcttt accgctataa
    13381 tccggacctg gcccgccagg gcaagaatcc gctgattgtg gaaggcaagg gcccgaaggg
    13441 cgatctgcgc gatgtgctgc tcagcgaaaa ccgcttcaaa cttctggcga agaccaataa
    13501 ggaaggattc gaaaaactcc ttgaagaagc ccagaaggat gtctggcacc gctggaacct
    13561 gtaccaaagc attgccggca tgggtgccga caaacctgcg gaataaggta taggccgctt
    13621 aatttcaacg cccctgtccg gcttatccgg caggggcgtt ttttactgcc ggatattcat
    13681 gaaaatcagg agatttatgt aaagattttt gagattct
//
