LOCUS       c00020_gnlPro..        15778 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CLIHIBEO_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 09:27:48
            Original ID  :: gnl|Prokka|CLIHIBEO_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15778
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15778
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2929:5778]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2930..5778
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..15778
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15778
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             complement(2..778)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MSLRYDAAFYVQVLDKYVATGECAEADNEPLYAYLLSVMNDPMIK
                     IQVLSDELCARIFYDAMSQFIRLNLEKQKYNMQKSQSEQQGMELVLEWSETKRKDGWQA
                     LLQEVADKHEGNGFDKAFYQGQFGNEGKYADEEVWERMVDDWKEAFQRDLQEQKEKEIE
                     QRKDDFERRLHANLRNIPGYIRQNNIEKDEFYQAWGLMSGMWNTVDFERIRKIVRIQKE
                     YPEVVKVANKMGRMADDEGQEQLHVAQGNVYKMEHSS"
     CDS             complement(768..2321)
                     /locus_tag="ctg20_2"
                     /transl_table=11
                     /translation="MEIKERIQLLLSEMNRGVYEKEAEIGLSLLAALAGESILLLGPPG
                     VAKSMVARRLKRAFVDARAFEYLMSRFSTPDEIFGPVSISRLKESDKYERAVDGYLPTA
                     DVVFLDEIWKAGPAIQNTLLTVINEKLFRNGDTELKLPLKLLVAASNELPTQGEGLEAL
                     WDRFLIRIISTCVKQEEAFYQMLLDDGDEEEQEACRWQISDEEYAGWQKEIRQIKVSAE
                     VLSCITEIRKNLEKVEIQGSEVHRNVYVSDRRWKNIVKLLKASAFIHGRKEVCLTDLLP
                     VYHCLWNEPEECADIRQIVVRALFVPYVKEIAAINLSLKSDLKVSRVREALEKARQKGD
                     RRDDDLMIIDHFYYQIENHGTGNTYIFIVDYKNLKEYSPKDVPATGVMYADPLNPKRTI
                     IRTFSDATKMKEQGAERVTLYRDEKNLYINGVRFPMRRLKRGEQQQLWLGNMTLTDRDY
                     ETELETAHDRIEKLVKDLSENIFISEEDKKGVAQYVATLRKEIAWARVDVRKLRYGDES
                     "
     CDS             2614..2895
                     /locus_tag="ctg20_3"
                     /transl_table=11
                     /translation="MEQIDNLKELINQGDVDIAIKQLDQLLQDDSVEKDKDMLYYLRGN
                     AYRKKGDWKQALNNYQYAIDLNPDSPAVQARTMAIDILNFYHKDMYNQ"
     CDS             2930..3157
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="Fer4_7 (E-value: 3e-12, bitscore: 40.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.6e-08, bitscore: 25.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 3.1e-08, bitscore: 26.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.9e-08, bitscore: 25.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 18.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAIVVDTERCKGCNLCVVACPLDVIALNKEVNMKGYNYAW
                     QVKEDTCNGCSSCAMVCPDGCISVYKVKVE"
     CDS             3170..4252
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_5"
                     /sec_met_domain="PFOR_II (E-value: 2.3e-27, bitscore: 88.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.5e-48, bitscore: 157.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVVLMKGNEAIAHAAIRCGADGYFGYPITPQSEVLETLAELK
                     PWETTGMVVLQAESEVAAINMVYGGAGSGKMVLTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLIALAPASVQEMADFVALGFELAFK
                     YRNPAIILADGVIGQMMEKVVLPAQKPRRTDAEVIEQCPWAATGKAKGRKPNIITSLEL
                     KPEAMEINNIRFQAKYKQIEENEVRFEEINCEDAEYLIIAFGSMARIGQKAMELAREKG
                     IKVGILRPITLWPFPSKAIAAYADKVKGMLVTELNAGQMIEDVRLAVNGKVKVEHFGRL
                     GGIVPDPDEIVTALEEKIIK"
     CDS             4263..4439
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MNPDKIRNVLNILFMILALAAIIVYFVVGKEDFKMFIYVCGAAIF
                     VKLMEFFIRFTNR"
     CDS             4452..5216
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-25, bitscore:
                     82.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEEIIKPENLVYKKPTLMNDNAMHYCPGCSHGVVHKLVAEVIE
                     EMGMEEKTVGVSPVGCAVFAYNYLDIDWQEAAHGRAPAVATAIKRLWPDRLVFTYQGDG
                     DLACIGTAETIHALNRGENITIIFINNAIYGMTGGQMAPTTLVGMKSSTCPYGRDVELH
                     GYPLKITEIAAQLEGTAYVTRQSVQSVPAIRKAKKAIRKAFENSMNGKGSNLVEIVSTC
                     SSGWKMTPEKSNKWMEEHMFPFYPLGDLKDKE"
     CDS             5236..5778
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_8"
                     /sec_met_domain="POR (E-value: 1.5e-35, bitscore: 115.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPAYGPEQRG
                     GTANVTVIVSDDKISSPILSKYDTAIILNQPSLEKFESRVKPGGILIYDGYGIINPPTR
                     KDIKVYRIDAMDAANEMNNAKAFNMIVLGGLLQLRPIVTLENVIKGLKKTLPERHHHLI
                     PMNEEAIKKGMELIHEV"
     CDS             5899..7941
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MRRILLLYILFSVVGLSAIHAQLNPARQQIDENGRDQYGNQVDPA
                     MIPDKLDSANVEVQGLPPTLYMWRIKNQLGDRTMIPADTTYHHFQNTNLTEGITGHYNY
                     LANLGSPRLSRIFFERRYPEPTIFMESFSSFFIRPTEFNFTNSNVPYTNLTYHKAGNKQ
                     NGEERFKSYFSVNVNKKLAFGFNIDYLYGRGYYNNQNTSYFNAALFGSYIGDRYQVQGI
                     YSNNYLKTNENGGITDDRYITAPEEMAEGRKEYESVNIPTVLNASANRNHDFYVFLTQR
                     YNLGFHRDIPQAENDTMPAKQEFVPVTSFIHTIQVERSRHNFRSDDNVENYYKQTLLDK
                     ENTFVRDSTVYIGVKNTIGIALLEGFNKYAKAGLTAFASHKLSKYSLMSLDPLKQDKYN
                     ETEIYIGGELTKKQGNFLHYHAIGEVGMAGKAIGQFDVKGDIDLNIPLWKDTVSVIARG
                     EISNKLAPFYMRHYHSKHFWWDDDMDKEFRTRIEGELSIANWGTRLRAGVENIKNYTYF
                     NQQALPEQKGGSLQVVSACFNQDFKVGIFHLDNEVIWQKSSDQAVLPLPELSLYHNFYM
                     QFKLAKKVLSVQLGADVRYFTKYDAPAYMPATQQFYLQPEEGKVEIGGYPIVNVYANLH
                     LKRTRFYVMMYHVNQGMSKPNYFLAPHYPINPRVLKFGLSWNFYD"
     CDS             7959..8798
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MKTRPKLRLFRYLLPVVIVLALIFSVRYCGKQEKPLGHPRDYAAI
                     AKEGILHVATEYNSISFYVDSDTVSGFHYELIEAFARDKGLKTEITPVMSFDERLRGLS
                     DGRYDVIAYGILATSELKDSLLLTSPIILNKQVLVQRKANGENDSLYIRNQLDLAQKTL
                     HVVKGSPSILRIQNLGNEIGDTIYIKEIEKYGSEQLISLVAHGDIDYAVCDESIARAVV
                     DSLPQVDINTAISFTQFYSWAVSKQSPALLDSLNTWLDKFQKEKEYQKIYRKYYGDK"
     CDS             9241..9762
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MELKQFKITVVPLRDKLLNYARRMTDDPSDAEDAVQEVMLKLWNL
                     RQKLDEYRSIEAVAMTMTHHLCMDMWRAKRPDTLSLDRVQAPTPSATPERLLEEKDEFR
                     LMREIIDSLPTLQRTIIRMKDIEEYETEEIAEITGCNAEAIRSNLSRARKKVREVYLQT
                     IQERKRRNKA"
     CDS             9759..10220
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MKDIETLLNKYFEGETTCEEERRLRRFFAEGLVPEHLEVYRPMFA
                     FFEAEQKELAEISGKGNAAEMPELAPFEKKTKTVRQYLTYSLSAAAAAILLLVGISGIY
                     RHLSPAPANYVIIDGKEYTDVHLIREQAMVAFRDVSLSEEEVFATLFDE"
     CDS             10241..10690
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MMNKIIRTTLITLLLTFAAHAAAQQGLQIATVFQKYGKQKGVTMV
                     ELSNEMLETYQMTLYKSLVFKDASDALPTILRCLEADKKKAKKVKEVVSNGQIKSGYYQ
                     LPQLKEDVNRFILFKTGKKDSATLIYIEGELDADDLITMLFMKKE"
     CDS             10715..11617
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="MKKLLLLWLMIAPMSGMAQNESTPQDTTLYVNGRKIVIKEQGDKI
                     KVKLYESASGGDTITNAQIFEGVYLNGQSTESRTVLSALPFSKKNNKRNRFEPHAGGFY
                     IGYTRLSNDFLSFNPSNGADLNTSHSWEIGGNLFTGSHAFAPTYNWGITIGLGWGYRSM
                     RLDGNYAFREIDGVTEIYSGMEAEEPTEYSKSRLRYFYFRIPLSIEWQTRLNGKGPLFF
                     AVGPEAEIRHGFRSKAKVNGSKKTIDKGLNGRPLGINLLAQAGYADLGVYMRYSTYGLF
                     EKNKGPELYPFSFGVCWYW"
     CDS             11731..12717
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_15"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 5.7e-27, bitscore:
                     88.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C (E-value: 5.5e-09,
                     bitscore: 29.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKMIKWGFIGCGEVTKTKSGPAFQKVEHSEVVAVMSRDGAKAK
                     AYAKERGIRKWYDDAQELIDDPEVNAIYIATPPSSHATYAIMAMKAGKPAYIEKPMAVT
                     YEECTRINRISKETGVPCFVAYYRRYLPYFQKVKEMVENGSIGNVINVQVRFAQPPRDL
                     DYNRENLPWRVQADIAGGGYFYDLAPHQIDLLQDMFGCILEASGYKSNRGGLYPAEDTL
                     SACFQFDNGLVGSGSWCFVAHDSAREDRIEIIGDKGMICFSVFTYEPIGLHTERGREEI
                     CIGNPEHVQQPLIQAVVDHLLGKSVCSCDGESATLTNWVMDKILGKL"
     CDS             12839..13309
                     /locus_tag="ctg20_16"
                     /transl_table=11
                     /translation="MTKEELMRKAIELSKENVANGGGPFGAVIATKEGEIIATGVNRVT
                     SSCDPTAHAEVSAIRAAAAKLGTFNLSGYEIYTSCEPCPMCLGAIYWARLDKMYYGNNK
                     TDAKNIGFDDSFIYDELALKPADRKLPSEVLLHNEAITAFEAWMSKEDKVEY"
     CDS             13347..14150
                     /locus_tag="ctg20_17"
                     /transl_table=11
                     /translation="MKRKNFLILLAAGCLFSCQQQDELQETSKEATNFSISIDDALSDP
                     LTRTSNDLFPARNSITTGEVISMAASGQDYTPFIVGKDSRAWNEIGTATGTVTFYAHYP
                     ALTDEAATRSGGNKRYLKGGQEHLFGTAEAAPGSQNVSLKFKRMTVPVIILDENDRPYE
                     GEAKVELSLKNEGTQDLLNGTIEINENALSENIEVKKVSEGVTTNVLPQKINAGEEIGT
                     ITVGGVTQKISAVEDLDLKAGSTLSVRLSKKFGGGIIDGNVPLYR"
ORIGIN
        1 tagaagaatg ctccatctta tatacattcc cctgcgcgac atgtagctgc tcctgtcctt
       61 catcgtcagc catacgcccc atcttattgg caaccttgac cacttccgga tattctttct
      121 gaatgcggac aattttgcgt atccgctcaa aatccaccgt attccacata ccgctcatca
      181 agccccaagc ctgatagaac tcgtctttct ctatgttatt ttgccggata tatccgggga
      241 tattcctgag attggcatga agtctgcgtt cgaaatcatc tttgcgctgt tctatctcct
      301 tttccttttg ctcctgcaaa tcccgttgga aagcctcttt ccagtcgtcc accatcctct
      361 cccagacttc ctcatccgca tatttccctt cattgccgaa ctgcccctga taaaatgcct
      421 tgtcgaaacc attaccctca tgtttgtcgg caacctcctg tagtaaagcc tgccacccgt
      481 ctttccgctt ggtctcggac cattccagca caagttccat tccttgctgt tccgactggc
      541 ttttctgcat attgtacttt tgcttttcca gattcagacg gataaactgg ctcattgcat
      601 cgtaaaagat tcgggcacaa agttcatcac tcaggacttg tatctttatc atcggatcgt
      661 tcatgacgga aagcaggtaa gcgtacagcg gttcgttatc cgcctccgca cactctccgg
      721 tcgctacata cttatccagc acctgcacat aaaatgcagc atcatatcta agactcatcg
      781 ccgtatctca gtttacggac atccacacgt gcccatgcaa tctctttacg aagggtcgcc
      841 acatattgtg ccaccccttt tttatcttct tcggaaataa aaatattctc agacaagtct
      901 tttactaatt tctcaatccg gtcatgggct gtctccaact ccgtctcata atcccggtcg
      961 gtgagagtca tattgcccag ccacaactgc tgttgctctc ccctcttcag ccgacgcatc
     1021 ggaaagcgga caccattgat ataaagattc ttctcatccc tgtaaagtgt caccctttcg
     1081 gcaccttgtt ccttcatttt ggtggcatcc gaaaaagtac gtataatcgt tcgcttcgga
     1141 ttcagcggat cggcatacat gactcctgtt gcaggaacat ccttcggact gtattctttc
     1201 agattcttat aatccacaat aaatatgtag gtatttcccg taccatgatt ctctatctga
     1261 tagtagaaat gatcgatgat catcaaatca tcgtccctgc ggtcaccttt ctgacgggct
     1321 ttctccaatg cttcacgcac gcggctcact ttcaggtccg actttaatga taagttgata
     1381 gcggctatct ccttcacata aggaacaaac agcgcacgga caacgatctg ccggatatcc
     1441 gcacactctt ccggttcatt ccacaagcag tggtaaacag gtaataaatc tgtcaggcag
     1501 acttccttcc gaccatgaat gaaagcagaa gctttcagca gcttcacgat attcttccag
     1561 cgacggtcgc tcacatagac attccgatgt acttccgagc cttgaatctc gactttctcc
     1621 aggttcttac ggatttctgt gatgcaggac aggacttcgg cagatacctt gatctgccgt
     1681 atctctttct gccatccggc atattcctca tccgaaatct gccaccgaca tgcttcctgt
     1741 tcttcttcgt caccatcgtc cagcaacatt tgatagaacg cttcctcctg tttcacgcaa
     1801 gtgctgataa tgcgaatcaa gaaacggtcc cacaaggctt ccagtccttc gccctgcgta
     1861 ggcagttcat tactggcagc caccagcagc ttcaacggaa gtttcagttc cgtatctcca
     1921 ttccgaaaca gcttttcatt gatgaccgtc agcaacgtat tctgaatagc cggaccggct
     1981 ttccatattt catccagaaa cacgacatcc gctgtaggca gatacccgtc cacagcacgc
     2041 tcgtatttat ccgattcctt cagacggctg atgctcaccg gaccaaagat ctcatcaggt
     2101 gtggagaaac gagacatcag gtattcaaat gcccttgcat ctacaaaagc tctcttcaac
     2161 cgacgggcca ccatcgactt tgccacccca ggaggtccca gcaacaaaat actttcgcca
     2221 gccaaagcag ccagcaaaga caaaccgatt tcagcctctt tctcatatac ccccctgttc
     2281 atttcggaca gcagcaactg tatacgttct tttatttcca tattattctt tgattctgca
     2341 cataaataaa gatgttattc accttaccgc ctatgcattg tttgcagata aacggcttgc
     2401 aaatatacgg ttttacctgt cattaacata aatacatctt ctctaattct gtcttttata
     2461 ctcaagaatt atcttaaggc atatttaata ttgattattt attcacccaa tatgcaataa
     2521 aaacaaaagg aggtaaattt cctttctcat tttcccccat ttacataaat aaaaactatc
     2581 tttgcgattc agaatcccga aagacgaaag aaaatggagc aaatagacaa cctaaaagag
     2641 cttatcaatc aaggggatgt ggacatagca atcaagcaat tggaccaact tctccaagac
     2701 gattctgtcg agaaagataa agatatgctc tactatttac ggggaaatgc ctaccgaaaa
     2761 aaaggagatt ggaagcaggc gctgaataac taccagtatg ctatcgatct taatcccgac
     2821 agccccgctg ttcaagccag aacaatggcg atagatatcc tgaatttcta ccacaaagat
     2881 atgtataatc aataaccgaa ttcaaagata acgtaataaa atagagatta tggcaaaaat
     2941 taaaggagca atcgtagtcg acacggagcg ttgcaaagga tgcaacctat gtgtagtagc
     3001 gtgtccgctc gatgtaatcg ccctcaacaa agaggtgaat atgaaaggct ataactatgc
     3061 ctggcaagta aaagaagata cctgcaacgg atgcagctcg tgtgcaatgg tttgtcccga
     3121 cggatgtatc tcagtgtata aagtaaaagt agaataaaag aaaaagaata tggcagaaga
     3181 agttgtatta atgaaaggaa acgaagccat cgcccacgca gctatccgtt gcggtgcgga
     3241 cggatacttc ggatatccta ttactcccca atcggaagta ctggaaacgc ttgccgaact
     3301 gaaaccgtgg gaaacaaccg gcatggtagt tctccaggca gaaagtgaag tggcagctat
     3361 caatatggta tatggaggcg caggtagtgg aaagatggta ttgacctctt cctcaagtcc
     3421 cggcgtgagt ctgaaacagg aaggtatctc ctacatcgca ggtgccgaac ttccttgtct
     3481 gattgtaaac gtaatgcgcg gcggccccgg attgggaacc atccagccga gtcaggcgga
     3541 ctacttccag acagtgaaag gaggcggtca cggtgactac aggctgattg ccctcgctcc
     3601 ggcatccgta caggaaatgg cggatttcgt ggcactggga ttcgagcttg ctttcaaata
     3661 ccgtaacccg gctatcatcc ttgccgacgg tgtaatcgga cagatgatgg aaaaagtagt
     3721 tcttcctgca cagaagccac gccgcaccga tgcagaagtt atcgaacaat gtccgtgggc
     3781 tgctaccgga aaagcgaaag gtcgtaaacc gaatattatt acttcactcg aactgaagcc
     3841 ggaagcaatg gaaatcaaca acatccgttt ccaggctaaa tacaaacaga ttgaggaaaa
     3901 cgaagtacgc ttcgaagaaa tcaactgcga agatgcagaa tatctgatca tagctttcgg
     3961 ttccatggca cgtatcggtc agaaagcaat ggaactcgcc cgcgaaaaag gaatcaaagt
     4021 aggtattctt cgccccatca ctttgtggcc gttcccgagc aaagccattg ccgcttacgc
     4081 tgacaaagtg aaaggtatgc tcgttacaga attgaatgcc ggacagatga tcgaagatgt
     4141 ccgcctggct gtcaatggta aagtaaaagt agaacatttc ggacgtctcg gcggtattgt
     4201 tcccgatccg gatgaaattg taactgctct ggaagaaaaa ataatcaaat aacgaaacga
     4261 cgatgaatcc cgataaaata agaaacgtat tgaacatcct tttcatgata ttggcacttg
     4321 ccgctatcat tgtctacttt gtagtaggaa aggaagattt taaaatgttt atctacgtat
     4381 gcggcgcggc aatctttgtc aagctgatgg agttttttat acggttcacc aacagataag
     4441 gagaagaagt tatgactaaa gaagaaataa tcaaacctga gaatctggtt tataaaaaac
     4501 cgactctgat gaatgataat gccatgcact actgcccggg ttgcagtcac ggcgtggtac
     4561 acaagctcgt tgccgaagtc attgaggaaa tgggcatgga agaaaaaacg gtgggagtct
     4621 ctccggtagg atgcgcagtt ttcgcctaca actatctgga tatagactgg caggaagccg
     4681 ctcacggacg tgcacctgca gtagctacgg ctatcaaacg cttatggccc gaccgtctcg
     4741 ttttcactta tcagggtgac ggtgacctgg cctgtatcgg taccgccgaa acaatccacg
     4801 cactgaaccg tggcgaaaac attactatta tctttatcaa taacgctatc tacggtatga
     4861 ccggcggaca aatggctccg acgactctgg taggcatgaa gagttctact tgtccttacg
     4921 gacgtgatgt cgaactacac ggctatccat tgaagataac cgagattgcc gcccaactgg
     4981 aaggaactgc ttacgttacc cgtcagtcgg tacaatcagt gcccgccatc cgcaaagcca
     5041 agaaagcaat acgcaaggca ttcgaaaatt cgatgaacgg caaaggttcc aatctggtag
     5101 aaatcgtatc aacttgtagc tccggctgga agatgactcc ggaaaaatca aataaatgga
     5161 tggaagaaca tatgttccca ttctatccac tgggtgattt aaaagataaa gaataacgca
     5221 aaagtcaaca gaacaatgaa agaagaaata attattgctg gattcggcgg acaaggcgta
     5281 ttgtccatgg gtaagattct ggcttattcc ggactgatgg aaggaaaaga agtgagctgg
     5341 atgccggcat acggtcctga acaacgaggc ggaacagcca atgtgacagt gattgtcagc
     5401 gatgacaaaa tctcttcacc gatcctgagt aaatatgata cggcgatcat actgaaccag
     5461 ccttcactgg aaaagtttga aagcagagta aagccgggcg gtatcctgat ctatgacgga
     5521 tatgggatta tcaaccctcc tacccgcaag gatatcaaag tatatcgcat cgacgcaatg
     5581 gatgctgcca acgaaatgaa taatgcgaaa gccttcaata tgatcgtact tggcggttta
     5641 ctgcaactcc gtcctatcgt aactctggaa aacgtcatca aaggattgaa gaaaactctt
     5701 ccggaacgcc atcaccactt gattcctatg aacgaggaag cgatcaaaaa aggaatggaa
     5761 ttaatccacg aagtttaata aattaagagt ttaaaattga gaattgagaa ttatttgcta
     5821 gataatagcg cgatgcaaca taattttcaa ttctcaattc tcaattctca atttaagtaa
     5881 gtatctttgc ctccaattat gagacgaatc ttactattat atatattatt ctccgttgta
     5941 ggactgagtg ctatccatgc acagctcaac cctgcccgcc agcaaatcga cgagaacgga
     6001 cgcgaccaat atggtaatca ggtagaccct gccatgattc cggacaaact ggatagtgcc
     6061 aatgttgaag tacagggact gccgcctaca ctatatatgt ggcgtatcaa gaaccaatta
     6121 ggcgaccgga caatgattcc ggcagataca acttaccatc actttcagaa tacgaatctt
     6181 acagaaggaa tcaccggaca ttataattat ctggccaatt taggttcacc gcgtctgtcg
     6241 cgtatcttct ttgagcgccg ttatccggaa ccaaccatct ttatggagtc tttctccagc
     6301 tttttcattc gcccgacgga atttaacttt acgaatagta atgttcctta tactaacctg
     6361 acctatcaca aggccggaaa taagcaaaat ggagaagaac gtttcaaatc ttatttttca
     6421 gtcaatgtaa acaagaagtt ggctttcggc tttaatattg attatctgta tggccgaggc
     6481 tactataata atcaaaacac ttcttatttt aatgccgcgc ttttcggtag ttacattggc
     6541 gaccgctatc aggtgcaggg aatctatagc aacaactatc tgaaaacgaa tgagaacggt
     6601 ggtatcactg acgaccgcta cattaccgca ccggaagaaa tggcagaagg aagaaaagaa
     6661 tatgaatctg tcaatatccc taccgtactc aatgccagtg ccaaccgtaa ccatgacttc
     6721 tatgtctttc tgacacaacg ctataatctg ggattccacc gggatattcc acaggcagaa
     6781 aatgatacga tgcctgccaa acaggaattt gttccggtca ccagctttat acataccatt
     6841 caggtagaac gttcgcgcca taatttccgt tcggatgata atgtagaaaa ctattataag
     6901 caaactctcc ttgataaaga gaatacattc gtcagagaca gtactgtcta tatcggagtc
     6961 aagaatacca taggtattgc tttgctcgaa ggcttcaaca aatatgcaaa agccggattg
     7021 acagcctttg cctcacataa gctgagcaaa tattcattaa tgagcctaga cccgctaaag
     7081 caggataaat acaatgagac agaaatctat atcggtggcg aactgactaa aaaacaggga
     7141 aactttcttc attatcatgc aatcggtgaa gtgggaatgg caggaaaggc tatcggacag
     7201 tttgatgtca aaggagatat cgacttaaat atccctttat ggaaagatac cgtcagtgtg
     7261 attgcacgcg gagaaatcag taataaactt gctccattct acatgcgtca ttaccactcc
     7321 aaacattttt ggtgggatga tgatatggat aaggaattcc gcacccgtat cgaaggcgag
     7381 ctgagcatag ctaattgggg gacccgctta agagccggtg ttgaaaatat aaagaactat
     7441 acttatttca accagcaggc attaccggaa caaaaaggtg gtagtttgca agtagtatca
     7501 gcttgcttca atcaggattt caaagtggga atcttccatc tggacaatga agtgatctgg
     7561 cagaaatcca gtgatcaggc tgtacttcca ttgccggaac tttcgctgta tcataacttc
     7621 tatatgcagt tcaaactggc gaaaaaagta ttgagtgtac aattaggtgc tgatgtacgt
     7681 tacttcacta aatatgatgc tccggcctat atgcctgcta cacagcagtt ctacctgcaa
     7741 ccggaagaag gtaaagtaga gataggcggt tatccgatag tgaatgttta tgctaactta
     7801 cacttgaaac gtacccgttt ctatgtgatg atgtatcacg tcaatcaggg aatgagcaaa
     7861 cctaattact tcctagcacc tcattacccc attaacccac gtgtgctgaa attcggactt
     7921 tcatggaact tctatgatta acaaaacctc tatggcttat gaaaacgcgc ccgaaattga
     7981 gactattcag atatctgttg ccggtagtca ttgtattggc acttatcttc tctgtccgct
     8041 attgcggtaa acaagaaaaa cctctggggc atccgcgtga ttacgcagcc atcgccaaag
     8101 aaggcatcct gcatgtagcc accgaatata attcaatcag tttttatgta gacagtgaca
     8161 ctgtctccgg attccattat gaactgatag aagcgttcgc acgtgacaag gggctgaaaa
     8221 ctgaaatcac tcctgtcatg agcttcgacg aacggctgag aggattaagc gacggacgct
     8281 acgatgtcat agcatacgga atactggcaa ccagcgaact gaaagattct ctgcttctca
     8341 cctcccccat catactcaac aagcaggtgc tggtgcaacg aaaagcgaac ggggagaatg
     8401 attcacttta tatccgaaac caattggacc ttgcccaaaa gacacttcat gtggtaaaag
     8461 gctcgccttc tattctacgt attcagaatc tgggaaatga aatcggagat actatttata
     8521 taaaggaaat agagaaatac ggttcagagc agttgatttc gttagttgct catggagata
     8581 tcgattatgc cgtctgtgat gaaagcattg cccgtgcagt ggtagattca ttgcctcagg
     8641 tagatatcaa taccgcaatc agttttactc aattctactc atgggcagtc agcaagcaat
     8701 cacccgcatt gctcgatagt ttgaatacat ggctggataa attccaaaaa gaaaaagagt
     8761 atcaaaagat ttaccggaaa tactatggtg ataaatagat aaaaaataat acgccgaaga
     8821 cttgactttc gcatttgaat gtcgtatctt tgtcaacgta atcataaagt agtttcagtt
     8881 aaactacacg taaaggaggg aatcacagtt ccctcctttc tttttgttac aatgaatgaa
     8941 aatcagcctt tttcccagct ttttgctcat tttacccccg agcttagtcc gttttacctc
     9001 gtttgttacc atacttaaca tagtatctta tgactaatta gatgctttgt tatgattaat
     9061 cagatgcttt gttatccata aaccgatgct ttgttctccc aaaacagaag ctctgtttcc
     9121 ggacagctcc caagagttaa caatcaataa agttgctctt gacaaaaatt tgctctactt
     9181 ttgaaaaaaa ttcccttttc gatgtcacgt ttttaatccg ccaccgtctt atcagtgtaa
     9241 atggaactga aacaatttaa aataaccgtt gtaccccttc gagacaagct gctgaactac
     9301 gcccgaagga tgacagatga tccttcggat gcggaagatg ccgtacagga agtcatgctg
     9361 aagctgtgga atctgcgcca gaagctagac gagtacagaa gtatcgaagc cgtagccatg
     9421 accatgacgc atcatctctg catggatatg tggcgtgcca aacgaccgga cactctatca
     9481 ctcgaccgtg tacaggctcc caccccttcg gctactccgg agcgactgct ggaagagaaa
     9541 gatgagttca gattgatgcg ggaaattatc gactccctgc ctacgctgca acgaacgatt
     9601 attcgcatga aagacatcga agagtacgag acggaagaga ttgccgaaat caccggctgc
     9661 aacgcagaag ccatccgcag taatctgtcg agggcccgca agaaagtaag ggaagtctat
     9721 ttgcaaacga tacaagaacg aaaaaggagg aacaaagcat gaaagatata gaaaccttgc
     9781 taaacaaata tttcgaagga gaaaccactt gcgaagaaga acgcagacta cgacgtttct
     9841 ttgccgaagg gctcgtaccg gaacatctgg aggtatatcg cccgatgttc gctttcttcg
     9901 aagcggaaca gaaggaactt gcggaaatct ccggtaaagg taatgccgcc gagatgccgg
     9961 aactcgcccc attcgagaaa aagacaaaaa cggtcagaca gtatctgact tacagtctca
    10021 gtgctgccgc tgccgccatc ctgctactgg tgggcatctc cggtatctac cgtcatctat
    10081 cccctgcacc ggccaactat gtgatcattg acggtaagga atatacggac gttcatttaa
    10141 tccgtgaaca ggcgatggtc gcctttcgtg acgtcagcct cagcgaggag gaagtattcg
    10201 ctactttatt tgatgaataa tataaaaaca gcatataatt atgatgaata aaatcattcg
    10261 taccacacta atcaccctgt tacttacatt cgccgcccat gcggccgccc aacagggact
    10321 acagattgcc accgtcttcc agaagtacgg aaagcaaaaa ggggtaacta tggtagagct
    10381 atccaatgaa atgctggaaa cttaccagat gactctttat aaaagtcttg ttttcaagga
    10441 tgccagcgat gcactaccta cgattctccg ttgcctggaa gccgacaaga agaaagcaaa
    10501 gaaggtgaaa gaagtggttt ccaacgggca aatcaagtcc ggctattacc aacttcccca
    10561 gcttaaggaa gatgtgaacc gctttatcct cttcaaaacc ggaaagaaag attcggctac
    10621 ccttatctat attgaaggag aactggatgc cgacgacctg atcaccatgt tattcatgaa
    10681 gaaagaataa aaaaacagat aaagaaatac gaatatgaaa aaactattat tactatggct
    10741 catgatagct ccaatgagcg gcatggcaca aaatgaaagt acaccgcagg atacaacact
    10801 ttacgtcaac ggacggaaga tcgtaatcaa ggaacaaggc gacaagatta aagtgaaact
    10861 ctacgaaagc gcatccggcg gagatacgat aacaaacgcg caaatcttcg aaggagtcta
    10921 cctgaacggg cagagtacgg aaagccgtac cgtgctgagc gctctcccct tctcgaagaa
    10981 aaacaacaag agaaacaggt tcgagccaca tgccggcgga ttctacatcg gctacacccg
    11041 actgtccaat gacttcctct cattcaatcc gtcgaacggt gccgacctca acaccagtca
    11101 ttcatgggag ataggcggca atctgtttac cggttcgcac gcctttgcac ctacctataa
    11161 ctgggggatc accatcggac taggatgggg ataccgcagt atgcgcctgg acggcaatta
    11221 tgcttttcgt gaaatagacg gagtgactga aatttactcc ggcatggagg cagaagagcc
    11281 tacagagtac agcaaaagcc gtctgcgcta tttctacttc cgcattccgc tctctatcga
    11341 atggcaaaca cggctcaacg gcaaaggtcc tttgtttttt gctgtaggtc ccgaagccga
    11401 aatacgtcac ggattcagat ccaaagccaa agtcaatgga tcgaagaaga cgattgacaa
    11461 gggactgaac gggcgcccgc taggtatcaa cttacttgca caagccggtt atgcagattt
    11521 aggagtgtat atgcgttact ccacctacgg cctctttgag aagaacaaag gtcccgaact
    11581 ttatccgttc tctttcggtg tatgctggta ctggtaaagt aaatactcag acccttgcct
    11641 atttctgaca gttaacaatc aataaagttg ttcttaataa aaaatagctt tatctttggg
    11701 agttgttaaa acaagcacaa taggtatatt atgagtgaaa agatgattaa atggggcttc
    11761 atcggctgcg gagaagtaac caaaaccaaa agtggccccg cctttcaaaa ggtagaacat
    11821 tctgaagtag tagctgtaat gagccgcgac ggcgccaaag caaaggctta tgcaaaagaa
    11881 agagggatca gaaaatggta tgatgacgct caggaactga tagacgatcc ggaagtaaat
    11941 gccatttata tcgccactcc tccttcttca cacgctacat acgccattat ggctatgaaa
    12001 gcaggcaagc ctgcctatat tgaaaaacca atggctgtca cttatgagga gtgtacacgt
    12061 atcaaccgta tttctaagga aacgggtgtt ccctgtttcg tcgcatatta ccgccgctat
    12121 ctcccctact ttcagaaagt gaaagaaatg gtagagaacg ggtctatcgg taatgtcatc
    12181 aacgtacaag tccgctttgc acagccgcca cgtgatttgg attacaaccg tgaaaatctt
    12241 ccttggcgtg tacaggctga tattgccggt ggcggttact tctatgacct tgccccgcat
    12301 cagatcgact tgctgcaaga tatgttcggc tgcatcctcg aagccagcgg atataagagc
    12361 aatcgtggag ggctttatcc tgccgaagat acgctgagcg cctgcttcca gttcgacaac
    12421 ggattggtcg gcagtggttc atggtgcttt gttgcccatg attccgcccg tgaagaccgc
    12481 atcgaaatta tcggagataa aggtatgatc tgcttctctg tctttacgta cgagccgatt
    12541 ggtctgcaca ccgaacgcgg ccgggaggaa atctgtatcg gtaaccctga gcatgttcaa
    12601 caacctctta ttcaggcagt agtagatcat ctgctcggta agtcagtctg ctcatgcgac
    12661 ggagaaagtg ctaccttgac taactgggta atggacaaaa tattagggaa gctctaagat
    12721 aaagctcctt cgtttgtttc ttaaaataat ttaatcacta tattctatcg ttagttttct
    12781 ttatatttgc gaaaggtagc aataaaagca aaactaacga tatttatttt ttataactat
    12841 gaccaaagaa gaactaatga ggaaagcaat agagctttcg aaggaaaatg ttgctaatgg
    12901 tggaggcccg ttcggagctg tcattgcaac aaaagaagga gaaattatag ctacaggagt
    12961 caacagagta acctcttcat gtgatcccac tgctcatgcc gaagttagcg ccatacgtgc
    13021 cgcagccgcg aaactgggaa cattcaacct cagcggatac gaaatctata cttcatgcga
    13081 accttgcccg atgtgtctgg gtgccatcta ttgggcacga ctggacaaaa tgtattatgg
    13141 gaacaacaaa acagatgcca aaaacatcgg tttcgacgat tcctttattt atgatgagct
    13201 ggctctaaaa cctgccgaca gaaaacttcc ctcggaagta ttattgcaca acgaagccat
    13261 tacagccttc gaagcctgga tgtccaaaga agacaaagta gaatattagc atctaatctc
    13321 acttaaactc actaatactt agtaaaatga aaagaaaaaa ctttttgatt cttctagccg
    13381 caggatgttt gttcagttgt cagcaacagg atgaactgca agaaacaagt aaagaagcaa
    13441 ccaacttctc tatctctatc gacgacgctc tctctgaccc gctcacccgt accagcaatg
    13501 atctgttccc tgccagaaat agcatcacta caggagaagt tatctccatg gctgcctccg
    13561 gtcaggacta tactccgttt attgttggca aagacagccg cgcatggaac gaaataggaa
    13621 ctgccacagg cacagtaacc ttctacgccc actatcctgc attgacagac gaagccgcta
    13681 ccagatcagg cggtaacaaa cgctatttaa aaggaggtca ggagcacttg ttcggaacag
    13741 cggaagcagc tccgggcagc cagaatgtat cactgaaatt caaacgaatg accgtgccgg
    13801 ttattatact tgatgagaac gatcgtccgt atgaaggcga agctaaagtt gagctcagcc
    13861 tgaaaaacga aggtacgcag gatttattga acggtaccat agaaatcaac gaaaatgcgc
    13921 tgtcagagaa tatcgaagta aagaaagtat ccgaaggcgt tactaccaat gttctcccgc
    13981 aaaagatcaa tgctggagag gaaataggaa cgatcactgt cggaggagtc actcagaaga
    14041 tcagtgcagt ggaagatctt gatttaaaag ccggaagcac actttctgtc agattatcaa
    14101 aaaaattcgg aggcggtatt attgatggta atgttccatt gtacagataa gaagattgca
    14161 cttaaagaca atcttgcaga ttatataaat ataaagaacg ggattcgtat gaatcccgtt
    14221 cttttattta gacctaaaaa ctatataata agccggtcag tccccaagag ccgaccgact
    14281 tatttataac actttattac ttatcccacc atacgcgtga tgtcatctta tcgcctccgc
    14341 taagtctctt aacggcatca ttgtaattaa caggattagc tgttatttca cttgtcggat
    14401 aaatgaaacg acgaggaatc tctccatttg tcacattgtt aggatagctg gctgcatttc
    14461 gagccggggt taattttgga tatccggtac gacgccaatt tgcaaaagct tcatactcat
    14521 tacagaacgt atggatataa tattccgtat taatctgttc cagcgctttt tccgtatcag
    14581 catccaatgg attagcattc agataggcag ttatcgcatc atctgtaatc gtagctgagg
    14641 ctttttcata ataggagaat tgtttcatgg cagcagttac tccatctcta taaaattttt
    14701 ctgcatctcc tgtatagagt ccacgtttca ctgcatcagc caataataac aagttaccgg
    14761 catgagtgac aagcatagag ggtgaatccg ggcgtgcata aactgtacgg ttaggaacag
    14821 aatatgcttt tctccaatca acctgatagc ttggagcttt actcaaatcc cagtctcctc
    14881 ctgacacatc ataaccaacc ggcatacctt tctgcttagc agccgtgttg tcacctaaat
    14941 caaaatcagc atctccccat cccggtttag gatctctggt acaaactgta gcaatcagag
    15001 gaagacgagg atcgtcctga aggatgttta taaatgtttc gctgatatag aacgcctgag
    15061 tatccagact ggaaaatact tttccgtaag gttctgcaga gtcatcgctt ggcgaaccat
    15121 tggtatgtct gacgatcgca ttatcatcgt tgcttacgaa cagcccattt gaaactgctt
    15181 tagctaccca tgttttcgct ttatcaggag caactttggt caaccgcatg gctacccgga
    15241 gcatcagtga attagcaaat ttcttccatt tcgcagcatc accgccatag ataacgtcag
    15301 cagctcctat cgtattaccg gcagaagtgc ttaatgcagc ttgtgcttca tctagttctt
    15361 tcagcagatc atcatagatt gcttcttgtg tatcatattt aggatacgga atcggattgg
    15421 tagaataccc ctgccctgct tcagaataag gaacgtctcc ataaaggtca gtcatattct
    15481 ggaacatata tgctttcaga atgcggcaca tctgatattc attcgtataa gcgggatctc
    15541 cttcccaatt attcatcaca tctataatat tgcgaatagc tgcacgccca ccagaataga
    15601 atcctcccca ataagcacca ctatactgat cgttccatgt atagaaaact ccatacgccc
    15661 aatctacgct agccgtatgc tgtatcatgt tggctgtgta aatacagcca ttacgccaca
    15721 cgtcccagtc ggagccacat atctgtgctt caacctgagt aaattccatt ttataatc
//
