LOCUS       c00018_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CBMPPDAM_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:47:56
            Original ID  :: gnl|Prokka|CBMPPDAM_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 20500
            Orig. end    :: 34189
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[30500:33990]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(468..1058)
                     /locus_tag="ctg18_29"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPILVQRIFQSDQQNEAKAAAE"
     CDS             1361..2908
                     /locus_tag="ctg18_30"
                     /transl_table=11
                     /translation="MTINWGERMALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIV
                     GYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANG
                     YQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLD
                     LLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDV
                     RFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVF
                     KFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKI
                     LAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGS
                     FLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKH
                     YEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             2972..3490
                     /locus_tag="ctg18_31"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLAEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             3590..4363
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_32"
                     /sec_met_domain="adh_short_C2 (E-value: 1.9e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             4801..5592
                     /locus_tag="ctg18_33"
                     /transl_table=11
                     /translation="VSISPFWISETEIPWELYTAFMENGRPRAKDGQLLEEQPDDELWD
                     SVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEWEY
                     ACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLD
                     SYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQ
                     NPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGEP"
     CDS             complement(5636..5821)
                     /locus_tag="ctg18_34"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCIQLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(5963..6178)
                     /locus_tag="ctg18_35"
                     /transl_table=11
                     /translation="MRDSCPPEGTEFPGAGGRIRFSPHGGNLLETFLRRNTGKLFLYRK
                     MPVKFGSALFVHMVHGSFHIAAFQAG"
     CDS             complement(6271..7011)
                     /locus_tag="ctg18_36"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7186..7275
                     /locus_tag="ctg18_37"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             7306..8013
                     /locus_tag="ctg18_38"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg18_39"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg18_40"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9779)
                     /locus_tag="ctg18_41"
                     /transl_table=11
                     /translation="VLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALMDVLPLLS
                     ASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_42"
                     /sec_met_domain="SucD_FumR (E-value: 1.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_43"
                     /sec_met_domain="FAD_binding_2 (E-value: 3e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.5e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_44"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6.3e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.4e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(13504..13689)
                     /locus_tag="ctg18_45"
                     /transl_table=11
                     /translation="GFVRHCQVRSPGLLGAFRCNNFLRCATMRKQLSGILFLVQGNLVM
                     KKLPTADAAGSFYRAS"
ORIGIN
        1 tctgtaatgc cgtgacatgg aacaagaaaa tctcttgatt tctacttgcc accatttaca
       61 ttggtgccag caaacctccg tggatgcgga ggttccagta gttaacaaac actgtattta
      121 attcgaatta tgaagaacat cgctatcctc gccatcgccg gcgccgcttg cctggtcgct
      181 tcttgctccc agcagcagca gcaacagcaa accaccgctc ctgctcccgc tccggttgtg
      241 caggccaagg gcaagtaagt ttgcagcagg gttttgccct gcaacactag caaattatcc
      301 aattaatccg cactcggtgt acgcactgag tgcgttttta tttgccctga gtccggattc
      361 cctccgccat ttgccgattc gccgggattt tccttaaaaa cggcggatac cgcaaaccgc
      421 cgcggcgcag caccgtgtgc cggttcctgc cggatcaggc ttccccttta ttcagcggcc
      481 gccttcgcct cattctgctg atcggactga aatatccgct gaaccagaat ggggcgtttc
      541 ctggcccacc cgggccagac caggtgatgt tccatgccgt aggaatggcc ctccggaaag
      601 gccttggaaa caaatggttc ccgccagtcc tcctcccatt tgccgccttc ccggtccttc
      661 tgggtcagcg tcaccagatg cccgcagttc ttccaggcat ccagaacaat ggagccctgc
      721 aatcccttcc ccgcggcatt gacatacacg caactgtgct cccggcccgt tccacggtct
      781 cgaatcgtca gccctatgcg gaaatacttc acggggcggc ggcgcaggtc ccggtacaaa
      841 tcctgctgga cctgccagca cagccccctg tcgcgcaggt tggaattgac cagaatattg
      901 ttcagccagc caaacagcac agtcctgttg tcccgggcaa tcgcggcgga ctggaccacg
      961 gccgtgtccg ccagccacct ggcctccgct ccggcagcgg gaagagaggc ctgatccggc
     1021 ggcagcagcg ccaggaaggc attagccagc ccggacattt gctgctgcac gtaagtttgt
     1081 tgtatataat cctccgccgg aggagtacag caggaactcc atccgcacaa aagggcggca
     1141 gcaagcaaaa gcctgaatgt ctgcgtggtc ggcatggcgc gccaaggcta gcagactacg
     1201 cgtaaaaatc cagtaaagct ttcaaaaatg cctgcctccg ccctgacggc tcttgccttc
     1261 ccctttccat cccggtagaa tacatcctct cttcaccatg ctgacgatca aaaatctcac
     1321 aaaatcccac gccggacgga ccttgttcag ggaaacggaa atgaccatta actgggggga
     1381 acggatggct ctggttggcc ccaacggagc aggcaaatcc accctgttcc gcatgattct
     1441 gggagaagac acgccggacg aaggctccat cagcatggat gaatacgcca tcgtgggcta
     1501 tcttccccag gaagccagcg aaccgaagga tgaaaccgtt ctggaaatcg ccctgggcat
     1561 cacgccggaa atggaacagg ccatccacac catccggacg gcggaaaacg ccaacaaaac
     1621 ggatacgccg gaatacgcgg aagccattga cactttcaac gccgccaacg gttaccagct
     1681 ggagcccaaa gccaagaaaa ttctcaaagg gctggccttt cgggaaagcg acttccaccg
     1741 ccccgcccgg gaaatgtccg gcggctggat catgcgcgcg tacctggcca aactccttgt
     1801 cctggagccg gacctcctga tgctggacga acctaccaac cacctggacc tcctgtccct
     1861 gctgtggctc cagcgatacc tgaaaaacta ccccggagcc atcctgatga tttcccacga
     1921 ccgggatttc atggatgagc tggtggaaag cgtgtacgac atcgacaacg aagaactggt
     1981 ggaataccgc ggcaattact cggacttcct ccaacaaaag gacgtgcgct tcgagcagct
     2041 tcaggcggcc taccgcaacc agcagaagga aatagcgcac attcaggaat ttattgaccg
     2101 tttccgctcc atcaattcca aagccgggca agtccagagc cgcatcaagc agctggaaaa
     2161 gatgaaaatc attcaaaaac cggtagcccg caggaaagta tttaaattca acttccccca
     2221 gcctccgcgc agcacccaga aagtcattga gctggaaaaa gtctgccaat cctatggcga
     2281 ccgcagggtt tatgaaaacc tggacctgct ggtggaacgc ggggagcgca ctgttcttgt
     2341 aggcccgaac ggcgcaggca aatccactct tctcaaaatc ctggcgggca tcatccccat
     2401 tgactccgga caacgcactc ccggtaccac gacgcgcatc ggctacttct cccaggcgcg
     2461 aacggaaaac ctgaatccgg aaaataccgt gctggaggaa atcatgaaat gcagcgctga
     2521 aatccgggag gaagaagcgc gttccatcct gggttccttc ctgttccgga ggctggatgt
     2581 ggaaaaacgc gtcagcgttc tttccggcgg ggaaaaatcg cggctcagcc tggtcaaatt
     2641 cctggtggat ccgcccaacc tcctgctgat ggacgagccg accacccacc tggacctttt
     2701 gtccgtagaa gccctggtgc aggctctgaa gcattatgaa ggaacactgg tcttcatctc
     2761 ccacgatgtg cacttcatcc gttccctggc acaaaaaacc ctgcatgtga accgggggac
     2821 catcaccgcc tacgcaggcg gatatgacta ttatctggaa aagtcaggca ttctggacga
     2881 tgaaaaaggc ggcatcacgg cggaataagg ctcttttttc agtttcccct ttttccttgc
     2941 cgtggatttc atcctgcctt aaaagaacag gatgaaggct tttcttgttc ctctcttata
     3001 ttctgcgctt ctgtccggag cctctcttgc atttggtgaa acggccgccg gaacggcttc
     3061 cccctcagca gcggctccgg cggaaaaaat tccttccgcg gaatccctga tcaaccaggc
     3121 cttttccttt gccatcaata tccagcagac gttggcaggc gttcaggaca aggaaagcgc
     3181 ggacaacgcc gtcaaaacgc tgcaggacat tcagaaggac atccggcatt tcctccagct
     3241 tcaggataaa ttgaacgatg cggaaaagga gaaagaagac gccttgatag aaaaaatgga
     3301 aaaacgaatg gaaatgctgg acaaccgctg caggcaggaa ggcaaacgcc tgtttgaggc
     3361 ccgctattac ggttccgccg ccttaaagga cattttggaa aattcggatg aattcagcga
     3421 cctggcagaa ccggatgaag acggggcgcc ccccggtgca ctccgggaaa atgaagaggc
     3481 cggacagtag cccccgcccc gtttctcccc cctctttttt cattcccggc acgccctttc
     3541 cccgtatggg ttcctgcgcg gccaagtcca tttcaagctt gccggaaccg tgaaaaacgg
     3601 gtttactgtg ggcagcatgc aaaagttagc aggtaaaaca gccatcgtta ccggcgcggg
     3661 ccgcggaatc ggcaatgccg tcgcgcgccg cttcgcttcg gaaggagcca gggtcatcct
     3721 gatcagccgc agtccatcca gctgcggggg ggccgcagaa gaaatcaaca aggaatttcc
     3781 ggattcctgc aaggcctacc cctgcgacgt agcggattac gcggccgttc aggaaaccat
     3841 ggccgccatt ttgaaagact tcccgcagat tgacatcctg gtgaacaacg ccggcatcac
     3901 gcgggactcc ctgatgctcc gcatgaaaga ggaagactgg gatgccgttc tggacaccaa
     3961 cctgaaaagc gcgttcaata cggtcaaggc cctccagcgc gttctcatga aatccccggc
     4021 cgggcgcatc atcaacatga gctccgtcat cggtctcgtc ggcaacatcg gccaggccaa
     4081 ttacgccgct tccaaggcgg gcctcatcgg tttcaccaaa tcactggcac aggaattcgc
     4141 tccgcgcaaa gtcacgtgca acgccattgc tcccggcttc atctccacgg aaatgtccaa
     4201 tgccattccc gacaatctca aggaagaaat cgttaagaaa atacctttga aagaacaagg
     4261 ttccgtggaa gatatcgccg ccctgacggc cttccttgcc tctgacgatg cccgttacat
     4321 caccgggcag gtcattgcct gcgacggagg catgacgatg tagggcattc cggttttctc
     4381 cattccatgc gtggcatttt ccttgtttcc tgctttctgg gaggaagcgc cctgctggcc
     4441 gggtgccggg aagaaaataa ttccccccgc ccggccacgg aagatgccgc gcgcattacc
     4501 agcgcacgcc agtggggaga aagccgatcc gcgctgcaaa aacgggaact ggaccgcgct
     4561 gccggtcctg cccttcccat tccggatgac ctgccgtccc gggagctggt cggcacgacg
     4621 cgccaaatcc atcagctcat tgaagcttcc ggaaatccgg cacgttttga atcctacacg
     4681 gaaacggttc ccgcggcggg agcttccctg cgcatggttg ccataccggg aggaacgttc
     4741 ctcatgggga gtcccgcgga agagccgcac cggaaaccgg acgaaggacc gcagcataaa
     4801 gtgagcatct ctcccttctg gatctcggaa acggaaatcc cctgggaact ttatacggcc
     4861 ttcatggaaa acgggcgtcc gcgcgccaag gacggtcagc ttctggagga acagccggat
     4921 gacgaactgt gggactccgt tacgcagcct accgccccct acgccgccat gaacctgggc
     4981 atgggccacg gctatgaaca cggcctgccc gccatctcca tgtcccacca cgccgccagc
     5041 aaattctgcg aatggctgag cgcccagacc gggcattact accgcctgcc cacggaggcg
     5101 gaatgggaat acgcctgccg ggccggctcc cccggcgcct attcttacgg aaacggggaa
     5161 gcctctctgg accagtacgc ctggtactgg aacaactcca atgaccgcta ccagaaaaca
     5221 ggctctaaaa aaccaaataa gtggggactc cgggacatgc acggaaatgt ggcggaatgg
     5281 gttttggact cttacgttcc ggatgcctac ggcaaacgga gcggattgcc cgcgaaagac
     5341 cccctggtca tcatccccgg cgcccctcac atcgttcgcg gcggttcgtg ggaagacgac
     5401 ccggacagcc tgagaagcgc tgcgcgccgc gccagcaccc ccgcctggaa ccgtcaggat
     5461 cctcaaaacc ctaaaagcat ctggtacctg acggacggag gcatgatcgg gttccgcgtg
     5521 gtgcgcccca tgaacattcc ggacgttatg acgatgcacc gcctctggaa tttctccaag
     5581 ggggagccgt aaagaacaat ctttcatgac cattgcatta agaacggaac aatcctcaga
     5641 ccatgccgaa acggaacatg tcacgagaga agcgttctga aactatttcg tccccggctg
     5701 caatgaacat tacctgctcc atatcatgcg cgtcagtcct tccttcatcc cggagctgga
     5761 tgcagtcgcc gtccacggca gccgcatcgt cgggaaacat cgttgatgca acgtccgtca
     5821 tcagggcaga cgatggaaaa gaatatgaag tgctgggcat ggggcccatt gccgttcttc
     5881 cggaatacca gtgccgggga ataggacggc ggataatagg tatgcggcgg ccctccaggt
     5941 ctgtgcgctg caaaggggtt ccctatccgg cctgaaaggc cgctatgtgg aagctgccgt
     6001 gtaccatatg gacgaaaagc gcgctgccga atttgaccgg cattttccgg taaagaaaaa
     6061 gctttccggt attgcgtctc aaaaacgttt ccagcaaatt gccgccatgc ggagaaaacc
     6121 ggatacggcc ccctgccccc ggaaattccg taccttccgg agggcatgaa tcccgcatac
     6181 ggataagcaa ttcttcctct ctggatataa aaaacaagag ctgttccgca agaacagctc
     6241 tcatccgccg atttttcgcc atcaggaagc tcaagccctg cggcggcgca tcatcagcgc
     6301 ggccagtccc agcaggccca gggaaaccgt ggctggttcc ggcaccattt cccctcggat
     6361 ttccgtgaaa atcggggata ataagctgaa agtattggtt ccgttggctc ccgtaataac
     6421 gacagaatca ccaggcgctc cctcggcgtc ataatggccg cggatgccgg gagcagtcaa
     6481 tccgccgctg atcgttacgg tatctccttc cgtgttagca gtaggggcgg ctgttccccc
     6541 cgcagcatat aaatacgttt tagacgtatc ctgcatcaag tccatcacgg actggctcac
     6601 ggccaggaaa cggtatgtca atgccgcgtc aagaagcagg ggagaaccat ccagggaaga
     6661 aaaactgaac gtcagattaa tccctgctgc agtagttccc gtattggtgc tccagccgat
     6721 gaccgaattg tcggagccat tcagcaccag gaagccgtaa gtgacattag cgcccaaatt
     6781 gttggcggct ccgcgcagcg taaaactgtc cagtctgatc tctccggaca gggaggaggg
     6841 agaagaggaa tcggaaggag ccagggaaga agaccccagg ccaagataaa acccatggat
     6901 ggtactattg taattatccg taccgggagt gtaataatta aaaacggtcg ctgcctccga
     6961 ggaaacagca aagcttccca tcgcgattaa aaatgtcagt gttttcttca tatttattat
     7021 tccttttgga tggcaacttg tagcgaattt ggaattcccc aatcggattt ggaatccgtc
     7081 aagtaatgaa aaagaggcca aatcaatcat gaaaccaatg aataacaaag actgacccgt
     7141 catcttgaca aaaggaccag agatattaaa aaatcattat tttcaatgaa ttataaatac
     7201 aatatactaa ctcttaatat ttttaattgc ttgcggattc caaattcgtt attcaagcac
     7261 aagtacatac attgaacctt gaatcatttt attaagatac tgaccatgaa taaattatta
     7321 tccaccctga ttctttcggc cggcatgagc ctgagcgcta ccgcggctac cgctctgttg
     7381 gatagctcca tcgtgggata ttcggacttt gcctcccaaa cggcggattt cggcacccgg
     7441 aaagattccg tttccatcac gtctgacgac agcaatctga cgttgtccgg gataaccttc
     7501 aacggatacg gtgccaacaa ccgcgacgtt atgtctgtga cgatggttct tgacctgtcc
     7561 aaaatcaaca ctccggagac ctataccgct ctgtttaacg ccaaaaacag cagtgtaagc
     7621 tggggcgtgg gcctgaacac ggaccggaaa ctccagggat tatggaacaa cacctcatac
     7681 agcgggcccg tcgttgacac cccgctgggc acggaaggtt ccctgaccat ttccgtagtc
     7741 accggagatc ttggcacccg catctatttt ggagacagcg ctacgtacta ttccaacagc
     7801 ggcctgaaat tcggcaacca gcaaattaat cagattctca tggacgcagg actggctgaa
     7861 tccatcgaac agctctacat ccacgactcc ctcctttccc aggaacaagt tggtcagctg
     7921 atgagtgaaa tcgccagcat tccggaaccc gccacggctt ccctgggcct gctgggactg
     7981 gccgcgctga tgatgcgccg ccgcagggca taagcctgta ccgtccgcct ccctatattc
     8041 aaaggccggc tcacaaaatc gtgagccggc cttttcctta tccgttcaaa catctgccgg
     8101 aaaaaacagg gggaagaagc ttctatttgc tgggtaccct cacggccagc acttgacggg
     8161 gaaatggcat tcaggctccc ccgggagggt catttcaaga gcttccggcc ccgccccact
     8221 tccgtacacg cccctttttc ccatgccggg acagccggaa ccggagcatg caaagcccgg
     8281 cttccctcag catccggaac agcccatcct ttcagcaatc catttccccg cacggtccgg
     8341 atcgctgcgg tttccgtccg tcggcaacag actccttccc tgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgaacttgaa cctttatccc ccgttcccat ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgtagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcggccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg cggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcccg ccatgaaatg atggatctgg tgttggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggt tgcaacgtca ctgccgccta caaagcctac aagcgtggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaaaggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaagaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ctccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccgtcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggccgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaacgtga aggggttgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaag cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca tcatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gccaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgcggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ccggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggcttcggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 cagatttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcccccag taatccagga gaccgtactt ggcaatgccg
    13681 gacgaaacc
//
