LOCUS       c00003_gnlPro..        16259 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OAOCPAKH_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 09:50:47
            Original ID  :: gnl|Prokka|OAOCPAKH_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16259
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16259
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1843:6259]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1844..6259
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16259
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16259
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             3..491
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="LASFIPSMTVMDDDGEPSVLPDPGSEPGGADSGWSRKKYWIRVIK
                     AWCRFEGRAGKGELHEVFSRVGVAWLAVAGVPSFAECGFFPSLVPWVELVSPLLYVVLA
                     VLSIPLAATMVRRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(523..1587)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MSFFSALTVPGLQQHLSFSREDSAILKGYGILFMIFHHVFGLYAL
                     PAGVDTAWIAPQLTKAAPIFKICVPIFIFITGYAMGWKTNSSPTFGSLIKTGFSHYFKF
                     WKIYFLCLLLAILVSWTFPLPILPSVADMGWKNGLLVVTGLRPCYPDWWYMALFAAATM
                     ALYPICAWITHHIAPVPSMAALLGVSLLLQSTAHIPSLPGIAYSFPPFLPCFILGYMCA
                     FLASRLSALSISQSLGAILLLALEILSIHLFSFSKAKTLTVIFLFTLWCLPWITRKLRL
                     TPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGTQSISVVFIVTLASSLLLAMAMQKLFN
                     RMIPSNPQTQSKTL"
     CDS             complement(1645..1785)
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MFKNRISNPKSTLYFENKWVIKMKGEEKRGGRNVPFFFFNPYCFW
                     A"
     CDS             complement(1844..4690)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="Beta_elim_lyase (E-value: 8.3e-11,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 4.6e-179, bitscore: 586.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSAACDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(4786..5166)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="GCV_H (E-value: 4.7e-48, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(5237..6259)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="GCV_T (E-value: 1e-83, bitscore: 271.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 8e-24, bitscore: 74.4,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPFAGWNMPVQYTGILDEHKAVRETCGIFDISHMGQFTVAGGSA
                     AAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLILYRMEPETFFVVVNASKIDEDF
                     AWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVIPGVELPPRNGISRITAEGTDL
                     IICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCGLGARDSLRLEMCYPLNGSDLS
                     PDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRLAAIEYTGKGAPPRAHYAVHVP
                     GGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELEIDVRGRKFPAVVVKKPFYKKG
                     "
     CDS             complement(6398..7519)
                     /locus_tag="ctg3_7"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(7578..8501)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="Peptidase_S11 (E-value: 1.9e-55, bitscore:
                     178.7, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGNSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(9061..10188)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWNGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLSPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPAGASTPLLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(10185..11240)
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MELGSGLSSRGVENIVVSGGGRLVPRLEKEGSRHILMPIGKKSIS
                     TLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPPEDRPGLVTSVHGFYSVNRY
                     SAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAISPDQYHPAYSPSREWLTGW
                     FMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGIPAHAVIVGEAKKGKEEYKN
                     EVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKSPEAFGKSTLEALALGKPVA
                     GYAHGGVKEQLDAFLPEGNVAVGDTASMADLLARWHAQPPPLPRQIPSPYNMQDMIQAH
                     LDVYQELTPYS"
     CDS             complement(11294..12424)
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MRAFFRTGHPAAGKTKLPGHGAQGIFNNRGIRSQHAGIMNKSMPP
                     TKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHLNQSLGLAQALISKAGGTVETV
                     DLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLICARHHFKTRAVLCMKPTLPCS
                     FFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPSVPKDTTLILIGGPSKDFDWDD
                     ESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAVPELTVVPVEETRPGWVARHLA
                     HASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRKSRILSGLETLEKEGMVTGYSD
                     WKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             12659..13381
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 67.4; E-value:
                     5.3e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_12"
                     /sec_met_domain="Fer4_16 (E-value: 2.4e-21, bitscore: 67.4,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0013, bitscore: 10.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRK
                     GGSRFFIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIE
                     HRGAIPEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLD
                     AGGFAALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAV
                     ERILRRHGRHASSSGARD"
     CDS             complement(13410..13607)
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="LFQDSLRSRATNSVNIRKGSLDALLVGYFCTEKACHNGLDLLAVI
                     FLCLAQSYCLGQDGYHKLRF"
     CDS             13695..13877
                     /locus_tag="ctg3_14"
                     /transl_table=11
                     /translation="LIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRTRTNART
                     RKGKKKTVGAQAKKK"
     CDS             13911..14462
                     /locus_tag="ctg3_15"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKLKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             complement(14474..14854)
                     /locus_tag="ctg3_16"
                     /transl_table=11
                     /translation="VAVGNKLTGAGTGIAEAEAVHNIVQTKLKELKQNIAGNAAAAGGF
                     CIILAELAFKHTVLETQFLFFSKHHAIVGFLLAAGAHAMLAGREGALFKSLGGTEKGNA
                     KTAGHFIAGTGITSHDILDLYR"
     CDS             14861..15109
                     /locus_tag="ctg3_17"
                     /transl_table=11
                     /translation="VNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRSLDLTQATVVPD
                     WLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             15242..16009
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_18"
                     /sec_met_domain="HAD (E-value: 4.6e-36, bitscore: 115.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYIFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 ctctggcctc ttttatcccc tccatgactg ttatggatga tgatggggag ccctccgttc
       61 tgccggatcc cggttcagag cctggaggcg ccgactccgg ctggagcagg aagaagtact
      121 ggatacgcgt catcaaggca tggtgccgtt ttgagggccg tgccgggaaa ggggagctgc
      181 acgaggtttt ttccagagtg ggggttgcgt ggctggccgt ggcgggagtc ccctcttttg
      241 cggaatgcgg ttttttcccg tccctggttc cgtgggttga gctggtttcc cctctgctgt
      301 acgtggtgct cgccgtgctg tctattccgc tggcggctac catggtccgg cgtctgcatg
      361 atgtcgggag gagcggcttt ttcctggttt ttctggccgt tcccttcata gggtggctgc
      421 tgttgtggta tttatcccat ggggaaagcc ggattggaga aaataagtac ggagatcccc
      481 cttggaatta agaggtgttg gaatccggac cttgtaaagt tgctacaaag tttttgactg
      541 tgtttgcgga tttgagggaa tcatccggtt aaaaagtttt tgcatggcca tggccagcag
      601 aagggaggag gccagcgtca cgatgaatac tacgctgatg ctttgggttc catagaggtc
      661 ccagctgaag tggtagccga aaatgaatct gtgattcagc cacataagtg cggaataagt
      721 tcccagcagc gtcaagagcg gtgtgaggcg gagtttccgg gttatccaag gcagacacca
      781 gagggtgaag agaaagataa ccgtcagggt tttggctttt gaaaaactga agagatggat
      841 agatagtatt tcaagagcca gcaacaggat tgctcccaag ctttgggaaa ttgaaagagc
      901 agagaggcgt gaagccagaa aggcgcacat gtagccgaga atgaagcagg gcaggaaagg
      961 agggaaggaa taggcgattc ccggcaggct gggaatgtgg gccgtacttt gaagtaaaag
     1021 ggacactccc agcagagctg ccatggacgg gacaggcgca atgtgatgcg tgatccacgc
     1081 acagattgga taaagggcca tggtggctgc cgcgaaaaga gccatgtacc accagtcggg
     1141 ataacagggc ctcaatcctg ttacgacaag caggccattt ttccaaccca tgtcggcaac
     1201 ggatggcaaa atgggcaagg ggaatgtcca ggaaaccaga atagccagaa ggaggcataa
     1261 gaaataaatt ttccagaatt taaagtaatg ggaaaagcct gttttaatga gggaaccgaa
     1321 ggttggggat gaatttgttt tccatcccat agcgtacccc gtgatgaaaa taaaaatggg
     1381 cacgcaaatt ttaaagatgg gagcggcttt ggtaagctgg ggagcaatcc atgccgtatc
     1441 cacacctgcg ggcagagcgt ataagccgaa gacatgatga aagatcatga agagaattcc
     1501 ataccctttg aggatagcgg aatcttccct ggaaaaagaa agatgctgtt gaaggccagg
     1561 aacagtaagg gcagagaaaa agctcatctg agacgtagct caacggattt ccaatccgaa
     1621 agagcaaaca tatccagaaa acaattaagc ccaaaagcaa tatgggttga aaaagaaaaa
     1681 aggaacattt ctcccacccc gcttttcctc ccctttcatt ttgatgaccc atttgttctc
     1741 aaaatagagt gttgacttcg gattggaaat ccgattcttg aacataagaa aaaggctgct
     1801 ccaaatgaat ggaacagcct ttttgaaagg aaggatgaga tttttataac tctacggcct
     1861 tggagaattc ctccaccgtg tcgcaggtgc agaccagatt gcggtctccg tacacattat
     1921 ccacccggcc tacatacggc cagaatttgt gaataaggag accggagacc ggataagccg
     1981 cttcactgcg ggagtagggg tgccgccatt cgtcggcgga gaccatttct gcggtatggg
     2041 gcgagttttt caggacgttg tcttccttgt ctgccgtacc gttgataatg gccgtgattt
     2101 ccgcatgaat gcgttccatg gcttcaatga agcggtccag ttcttttttg ggttccgatt
     2161 ccgtcggctc caccatcagg gtgcccggaa cggggaagga catggtgggg ccgtggaagc
     2221 cgtagtccat gagccttttg gcaatgtcat ccaccgtgag gccggcgtca tgagtgagct
     2281 gacgcggatc cagaatgcat tcatgcgcca ccagcccctt gttgccggag tagagaaccg
     2341 ggaagagatg tccgagtttc ttggcaatgt agttggcgtt aaggatggcc atttccgtgg
     2401 cttccctgag gccgtccggc cccatcatgg agaggtacat ccagcagatg gcggcgatgg
     2461 aggcgcttcc ccacgccgca gacgctacgg ccccttcttc atggcccagc gtgaggtgcc
     2521 cgggcaggaa gggtacgagg tgttccgcta cgccgatggg cccgatgccg ggaccgccgc
     2581 cgccgtgcgg catggcaaag gttttatgca ggttcaggtg gcagacgtcc gcgccaatgc
     2641 agccggggca agtcagacct acctgggcat tcatgttggc gccgtccatg tacacctggc
     2701 cgccattggc atggacgatg tcgcagagtt ccttgattgt ctgttcatat accccgtgcg
     2761 tggaggggta cgtgaccatg atgcaggaga gattgtcctt atgggcttcc gcctgggatt
     2821 tcaggtctgc catgtcgatg ttgcctcttt cgtcgcattt gacgggcacc accttgaggc
     2881 cggccatggc ggaggatgcg ggatttgttc cgtgggcgga ggtgggaatg aggcagacat
     2941 tgcggtggcc ttctccggcg tgcttctggt agcggcggat ggccagtagc ccggcatatt
     3001 cccctgcggc gccggcgttg ggctggaggg atacagcggc aaagccggtg attttcgcca
     3061 gacggtcgga caggacggag agcatttccc ggatgccttc cgactggtcc gccggaacaa
     3121 agggatgcag ggagttggct tccggccacg tgatgggaat catttcagag gcggcgttca
     3181 gcttcatcgt gcaggagccc agagggatca tggcttcatt tagagccagg tcccgggatt
     3241 ccaggcggcg gatgtagcgc atcatttccg tttcggaatg gtaggagttg aaagcctttt
     3301 ccgtgcagaa aggcgtctgg cgcgtgtgga cgggatccca ggcaggagcg tcgcaatcgc
     3361 aggcggcgga tgtttccgca ccagcaaggg cggaggccag tgccgctata tccgcacagg
     3421 ttgcggtttc atccagagag atggctgcgt ggtcggcatc caccctgcgg atgttatacc
     3481 cggcttccag ggctttttgc accatggcgt ccgcttgtcc gggaacggac agcagcaggg
     3541 tgtcaaagaa gtttttgttt tcaatggcga tgccggcttc cgtgagcgcc ttgtacaggc
     3601 ttttggtttt caagtggatt tccgtgccga tgcgtttgag gccttcctgg ccgtggtata
     3661 cggcgtaaaa ggcggcaagc acggccagga gcacctgggc ggtgcagatg ttggaggtcg
     3721 ccttgtcgcg gcgaatatgc tgttccctcg tttgcagggc caggcggtag gccgggcggc
     3781 ccagggtatc tatggacatg ccgataaggc ggccgggcat gcggcgtttg agagcgtccg
     3841 tgcaggacat gtaggcggca tgggggccgc cgaagcccat tgggatgccg aagcgctgcg
     3901 tgttgccgat gcagatatcg gctccgaagg cgccgggttc ccggatgacg gtaagggcca
     3961 tgagatccgc tgccacgacg cagagcgcgc ccgtggcatg cacgcgggaa aagaagtccg
     4021 tgtagtcgca gatgcggccg agcgtgtccg gatattggac aagcactccg gccagatccg
     4081 caccgatgga tgcggggtca aaggaggagc aatctcccac gatgatgtta acgccctgga
     4141 aggcggcgcg ggtacggatg acgctgatgg tctgggggtg gcaggtgtcc gccacaaaga
     4201 aggtgtttgc tttggggcgc gcgttccggc acatggtgac tgcttctgct gctgcggtgc
     4261 cttcatccag cagggaggcg ttcgctaccg gcagccctgt cagggaagag accatggtct
     4321 ggaaattcat gagcatttcc agccgtccct gggcgatttc cggttgataa ggggtgtagg
     4381 ccgtgtacca gccggggttc tccagtacat tgcggaggat gacggaggga gtgatggtgc
     4441 cgtaatagcc ctggccaatg aaggttttca ggagcttgtt tttccgcaga atggaacgga
     4501 gttcctccag ggcttccgtt tccgatttgg ctgcgggcag gtccagcggg gccttcatgc
     4561 ggatatctgc ggggacgatg tccgcaatga gttcgtcaag cgtccggtag ccgaggctgt
     4621 caagcatttc ccggcgttct tccccctggg ggccgatgtg ccggctggca aaatctgagt
     4681 gggtattcat gtggtatctc tggctggtaa tagcgtccgg ccgcggaacg ggccaaacaa
     4741 aatgccccgg gatggaatca ccggggcggg ggagggaaga atggttcagg agcagtattc
     4801 ctcgtaatcc gtggcgttca tcatatcttc cgtttccgtg ggaacgtcca ggcggatttt
     4861 gtacagccag cctgcgccgt aggggtcgga gttaatgagg gacggatcat tggaaagctc
     4921 ttcgttcact tccaggattt ctcctgaaac gggggtgtac acgtcgctgg cagctttgac
     4981 agattccacg acagcgacag ggtcgccagc tgcgacggtg gcgcctactt cgggaaggtc
     5041 tacaaagacg acatcggaga gttcggcctg ggcatggtcg gaaatgccga tggtgccgat
     5101 gtccccgtca atttcaatcc attcgtgatc tttggaatac agcagatttt ctggtacgtc
     5161 gtgcataaga tgtaattgtt tgaagtgaga gtgtagtaaa atgaggtgtt tgtcagttta
     5221 tttttgcgcc gtagtgtcag ccttttttat aaaagggttt ttttacgacc acggctggga
     5281 atttccttcc ccttacgtca atttccagct ccgtgccgac cttggcatgg gcggcaggca
     5341 ggtaggccag ggcaatgccc ttcatcagcg aaggagagag cacgccgctg gtaagttctc
     5401 cgatggcttc tccaccgggg acgtgcacgg catagtgggc gcggggagga gctcccttgc
     5461 cggtgtattc aatagcggcc agccgacggc tgaggccgtt ggctttttgt tcccggagaa
     5521 tatcggaacc gatgaagtcc gtatccagcg cgcagaagaa tccgagcccg gcttccagag
     5581 gcgttttgtc cggagagagg tcggagccgt tcagaggata gcacatttcc agacgcaggc
     5641 tgtcgcgggc gcccaggccg cagggtttgg ctcctgctcc aagaaaggct tcaaaccatt
     5701 tgacgccttc cttagccggg cagaagaatt caaaaccatc ttccccggta tagccggtgc
     5761 ggcagataat gagatccgtc ccttccgccg tgatgcggga gattccattg cgggggggaa
     5821 gttccacgcc ggggatgacg cgggagaata cttctccgca ttcgggacct tgaacagcca
     5881 gccccacgta ttcgtcggag tggttttcca gagttacgcc tgcaggttga tgggcggaaa
     5941 gccatgcgaa gtcttcatca atcttggagg cgttcaccac tacgaagaag gtttccggtt
     6001 ccatccggta caggatgagg tcgtcaatga ctccggccct gtcattgagc atgacggagt
     6061 attgcccctg ccctacattc agtttgttga tgtcattggt cagcatggag ttcagccatg
     6121 ccgcagcgga accgccggct accgtgaact gccccatgtg ggagatgtca aaaatgccgc
     6181 aggtttcgcg cactgctttg tgttcgtcca gaatgccggt gtactgcacc ggcatattcc
     6241 agccggcgaa aggaaccatt ctggctccca gttcaacgtg tttagttgcc aggggggtgg
     6301 atttgacgtc tgtatcagtc atgaggcgat gtgaaggtta tgagcaatct gccccttata
     6361 tcagtaaaag tcaatggaat tccggtaacg cttccgtcta gacattgaag cggaattcga
     6421 tgacgtcccc gtctttgacg acatattctt ttccttcgat gcgcagcttg ccgtgttccc
     6481 tcgctccggc cttgccgccg caggaaacca agtcgtcgta gtgcactacc tccgcggcga
     6541 taaaaccgcg ttcaaagtcc gtgtggatga cgccggccgc ctggggtgct tttgccccgg
     6601 ccggaatggt ccaggcccgc gtttccttga ttcccgtggt gaggtaggtg cgcaggccca
     6661 gaaggtggta cacggcgcgg ataaggtcgg aaacgccgga gtccttcaca cccagggatt
     6721 ccaggaattc gcgggattct tcctccgaga cgtcgatgag ttcctcttca atccgggcgg
     6781 agatgacaat ggcttccgcg ttatggtgtt ccgctacgta ttttttcacc tgggagacgt
     6841 agggatgggc gtccgggttg gagatggcgt ccgccagttc gtcttcattg acattgcagg
     6901 cgaaaatgct ttttttatcc gaaagcagct ggaaagaatg gagcagcttg cgttcatcgt
     6961 cgtccagctg cggttcaagg gtgagggcgg gattgccttc gttcaggtgg ggcaggagtt
     7021 tggtgatgag ggccacttcg gccttggctt ccttgtcgcc gctgcgtgcc ttgcgttcgc
     7081 gggaagagag tctcttttcc atggtggcga tatccgccag aatgagttcc gagttgatga
     7141 tgtcaatgtc gcgcagagga tccacggaac cgagttcatg gataatatca tcattgtcaa
     7201 agcagcggac tacctgcacg atggcgtcca cttcacggat gttcgccaga aactggttgc
     7261 ccaggccggc tccttccgag gctcccttga ccagaccggc aatatccacg aattcaataa
     7321 gcgtggggat gattttttca gaaccggaca tgtcggaaag aacctgcagg cggggatccg
     7381 ggactgttac catacccacg ttcgggtcaa tggtgcagaa gggatagttg gccgcctggg
     7441 ccttgcgcgt ccgggtgacc gcattgaata gagtggattt gccgacgttg gggagaccta
     7501 caatacctgc ctgtaacata ggcaggactg atagcgggtc acgccgtgaa agtcaaatac
     7561 caattgccga cgggcattta tgcggcggat cccagagccc atctgatcag gttttccgat
     7621 tccgtccaga tacgggacgg atggcagccg aggacgacga cgatgacatg gcgcccgttg
     7681 acgccggctg aggaaaccag gcagcgtccg gcggcgttcg tgtatccggt tttcattccg
     7741 gtaacccagg ggttctgggt gagcagcttg ttggtgtttc tcagcagaag cgttctgccg
     7801 ttggcgcggg taaaggcata ttggcgtttg cagataatat tgcgcagttc cgggttgcgg
     7861 tacacataat aggcgcagcg ggccatgtca atggcagtgg aatattgatc cgccgggagg
     7921 ccgttgggat tggcgaagcg tgagttgtac atgcccatct gccgggcttt ggcattcatc
     7981 aactgggcga aacggggaac ggaacccgcc gtatcgcggg ccagagccag ggctacgtcg
     8041 ttgaaactgc ggatcatcat ggcattgagc agttcgcggc gtgaatagac ttcccccgcc
     8101 cggaatccca gtttggtggg gtccgccttg gtatcggaag gctggatgac cacttttttg
     8161 tccaggctgc cgtgttccat cacgaccatg gccgtcacga gtttctgcgt gctggctacc
     8221 tggcggtgct ggaggccgtt gtgggaaaag agcacgttgc cggtaagggc gtccatgacg
     8281 caggcgctgg cgcagcgggg cgtgcgtggg gcgcttgagg ggatggctac gggacgtgtg
     8341 gggaaattgg ccggtcgggg gagggcatgg gaaaccggct gggagagttg tgggggaacg
     8401 ggcgttgcaa gggggatgta gtcacttgaa ttcccgtacg attggcagct tgtggagctc
     8461 aggcaaaggg agaatcctgc aagaagggcg aataaacgca tgtcttgttg ctacagtaag
     8521 aagtttcgtt catcaagccc aaactccgca tttgaaagag agccggacga aaaaggccgc
     8581 ggatcggaca atccgcggcc ttttttctct attaactacc tatggaacca aaaaccaccc
     8641 tgaacggatt ttgaattgct tttcccatcc gtcggacaga tcttgtgaag gatgagactc
     8701 caggcaggag tgatgcgttc aaaatatgtt cgtcaacaat tctttttaag aggtgttgcc
     8761 gtatgagccc gagcctgcgt ccagtaaata tggcagagat tttttccgaa catattttgt
     8821 ttttcgcgag catgtaaatt taccgcaggc atttaaaatg ccggggatgt cctgccgata
     8881 tatttaattt ttggaataaa attattgaag gaaaggattt ggcgactgtt ttaagacgtt
     8941 tttttgcatc cggatggaaa ggtttttata cgggagatgg acggcgctcc cttccggttc
     9001 catggtcagg gagaggaggc ccggacctgg cgttttcccc ggcggaaaag cggaatcttc
     9061 ctaaagttcc ctgccgttaa tggagaaata ccctccggcg tccggagtaa tttgccctgc
     9121 aatttgcatt ttggccaaaa gcggggtgat ggtatgcgcc gcttttccca gagaggtgca
     9181 gagggtgtca atagtattga aacccagtct gatggcgtgg agaatctcct tttcttccaa
     9241 agtgggaagc agtggggttg aggctccggc agggggacat ggcgagaaga gaggcagtcc
     9301 ctgttccgga acggcccagt tcatgtcctg cagaatatcg gaggctccgg tagccaggat
     9361 ggctccgtcc cggatgaggg catggcatcc gtcggaagaa tgccggtcaa ccggtccggg
     9421 aatgcagaaa acctctcggc cctgttcggc cgccgttcgg gccgtgatca gggccccgct
     9481 gcgtccggac gcctccacca ccagcgtagc gcggctccag ccgctcacga tgcggttgcg
     9541 catgggaaaa gtggtgcggg agggggacag gtccattggg aactcggaga ctaccgctcc
     9601 atgcccgtcc gcaatgcgct gcgccaagtt tctgttttcc cgaggataca gtttgttgag
     9661 acctgccccg ataacggcga tggtgcgccc ctccgcgtcc atggccccgg tatgggcttc
     9721 cgtgtccaca ccgcgcgcca gtccggaaat gacggtgact ccggcttccg ccaggtcatg
     9781 ggagatgttt ctggcgcaaa gcctgccgta atgggtggcc atccgtgagc cgacgacggc
     9841 aatggagcgt tcggcatccg ttccgttcca gtttccccag gagtagagga caatgggcgg
     9901 gtctgggaga gcacgcaggg aggatgggta ggagtcgtca aaaaccgtgg ttactgcggc
     9961 ccccgcgtta tccgccagtt ccagttccct gtacgggttg acgatgctcc gccaagagga
    10021 aatgcggcaa gccagctgcg cccccacgcc gggaatttcc atcaacaggg aggaagggga
    10081 ttccagaatc agttccggag aggcgaatac ctgcaggaga cgcatgattc tgacagggcc
    10141 caggcccggt atcaggttca gggctatggc tgcttcccgg ggtgtcatga ataaggggtc
    10201 agttcctggt aaacgtccag atgggcttga atcatatcct gcatattgta aggggaagga
    10261 atttgccggg gcaggggggg gggctgggca tgccagcggg ccagcaggtc cgccatggag
    10321 gcggtatctc ctacggcgac gttcccttca ggaaggaagg cgtccagctg ttccttgact
    10381 ccgccgtggg cgtatccggc cacaggtttg cccagggcga gcgcctccag ggttgatttg
    10441 ccgaaggctt ccgggctttt ggtcagggag agggtgacgg aacatgtgga aaggatttcc
    10501 ctcagatcct ggcgatgtcc tgtccaggtg aaggactggg agacgccgga acgttctatt
    10561 gcccgcagga cctcgttttt atattcttct tttcccttct ttgcttctcc tacaatgacg
    10621 gcgtgggccg ggattccctg ttccagaagc tgcctgacga ccggaatcag atccagatgc
    10681 cctttcaggc gcgtgatgcg gcccggcagg cacagggtga atttcccctt cagttcagga
    10741 taggacatga accagcccgt gagccattcc cgggaggggg agtaggccgg gtgatattgg
    10801 tccggggaaa tagcattggg tatgattctg atatggtccg gaggggtgga cggataatgg
    10861 tcaaggatgt agtccctgat gcagttggag acggcgatca cccgctctcc ccggctcatg
    10921 atggcggagt accggttgac ggagtagaag ccgtgaacgc tggtgacgag gccgggacgg
    10981 tcttcgggcg ggagcttttt ccatgccagg tagcctgccc acgcaggaac gcgggaatgg
    11041 agatgcagga tatccggcct gacggcctga agcagggcgc ggagggcccc gatgcggaag
    11101 agagtggaga tgcttttttt gcctatcggc atcaggatgt ggcgggagcc ttccttttcc
    11161 agacggggca ccaggcgtcc gcctccggaa acgacgatat tttccacgcc ccgggaagaa
    11221 aggccgctgc ccagttccat aacgacttgt tccacgcctc cggattccat ggaggggacg
    11281 agatgtacta ttttcataag gcgcggagct gagggaaaaa tctggagagg atgtagtctg
    11341 ctgcacggtc cgcttccaga agcggggaac cgggagccgt caggcggaag ttctgttttt
    11401 tccagtcact gtatccagta accatgcctt ccttttccag tgtctccagg ccggacagga
    11461 tgcgggattt gcggctgccg tgtcggcgcg gtacggaaag gatgcctaca ggcgcgccgg
    11521 agccaagagc ctcatatacc atggagacgc tgtcctggct gacccaggcg gcggaggcgt
    11581 gcgccagatg ccgggctacc caccccggcc gggtttcctc cacgggaacg acggttagtt
    11641 ccggaacggc cgtccggatt ttttccgcaa agccgtccgg cgtccggcgc gaggtggtta
    11701 gaacaaggtg tccgggggtg tggatgctga tggacgcgag ctggttgagc atgctttcgt
    11761 catcccagtc aaaatctttg ctgggccctc ctatgagaat cagtgtggta tcctttggta
    11821 cggagggatc cggcctcatg gggtggagag ctccctgggt ggggaagata tccgtatccg
    11881 tgtaatcgcg gccggaatcc aggtcatggc ggggaataag gcagaggtcg aaaaaggaac
    11941 agggaagcgt aggcttcatg cagaggacgg cccgggtttt gaaatggtgc cgcgcgcaga
    12001 tgagcgggat atgcgttgca tgtccggcgg aaatgaacag atccggccgt ggaatgtcgc
    12061 tgcctgtgac gaccttccgg attttcccca aaagggaaag cccctgcagg tctaccgttt
    12121 ccacggttcc ccccgctttg gagatcagag cctgcgccag ccccagggac tggttgaggt
    12181 ggccctgttt cccatcgctc agaatccgga tgttcatata tgcggcatta tgaagcggcg
    12241 gcggggtgca ggcaatccaa tttccaccgg acagaagaaa attcttggtg ggaggcatgc
    12301 tcttgttcat gattccggcg tgctgactcc ggattcctct gttattaaag attccttgtg
    12361 cgccgtgtcc cggcagcttg gtttttccgg ctgccgggtg gcccgtgcgg aaaaaagccc
    12421 gcatgcggaa aaattgtttc aatggctgga gcgcggatgg cacgccggga tggagtggat
    12481 ggcgcgttcc ccggagcggc gcacggatcc tgcggaagtg cttcccggat gccgttcagt
    12541 catttgcctg tcctatgatt atgacagccc cggtaggcgc ccggaggggg agggtagcat
    12601 ttgcctttac gcccatggaa aggattacca cggaattctg gaggaaaaac tggcggattt
    12661 gcaggagctg ctttccattt acggcgggaa gcagaggggg tatgtggact ccggccctgt
    12721 tatggaacgg gaccatgcgg aggcctgcgg cctgggctgg cgcgggaaaa gcggtttgat
    12781 cgtgcgcagg aaagggggct cccgcttttt tatcgctacc ctgctgacta cgctggaact
    12841 ggaaccggac gctccggttt caaacggatg cggcagttgc cgccgttgtg cggccctgtg
    12901 tccgacgggc gcaattatgg aaaacggtca ggttgatgcc ggacgctgcc tttcctactg
    12961 gacgattgaa caccgggggg ctattccgga agaaatccgt cccctgatag gcacgcgcct
    13021 gtacgggtgc gatacctgcg tgacggtctg tccctggaat ggtaagcctt tgccggacgt
    13081 tgacgaacgg ttccgcatgt cccgtctgct ggcttccatt cccctgcgtg gtcttctttc
    13141 cctggatgcc ggcggttttg cggccctgtt ccggaattcc ccgttgaaaa ggctcaagag
    13201 ggaagggctg ctgcgtaacg gctgcgttgt gctggggaat gcggggactc cggatgacat
    13261 tgattttctg aaggcgcttt acggggagtc tcctctggtg gaggaacacg cttcctgggc
    13321 tgtggagcgc atcctccgcc gccacgggcg gcatgcatct tcaagcggtg caagagatta
    13381 aaaatagaaa aaatgatgtt ttggtcttgt caaaacctca atttatggta tccatcttgc
    13441 cccaagcaat agctctgcgc gaggcagaga aaaataacag ctagcaaatc caatccatta
    13501 tggcacgcct tttcggtaca gaaataccca acgagaagcg catcgaggct tcccttccgt
    13561 atatttacgg aattggtcgc tcgacttcta agagaatcct ggaacaagca ggcatcaatc
    13621 ccgacatccg cacgggacag cttaccgacg aacagctcac gaagattgtt caagtaatca
    13681 ccaccgacgg cattttgatt gaaggtgacc ttcgtcgtga aaagcaatcc attctcaagc
    13741 gtctgacctc catcaactgc tatcgtggtc agcgccaccg ccgcggcctt ccggtacgcg
    13801 gtcagcgtac ccgcacgaat gcccgcaccc gtaaaggcaa gaagaagacc gttggcgcgc
    13861 aggccaagaa gaagtaatcc gccaacctga atttttaata tagctttact atggctagcg
    13921 aagaaatcac caacgaaacc gccgaacagc ctgtggaagc ggcagcttcc gctcccgtcg
    13981 ctgaaactcc ggccgccgct gtttccgctc ctgaagaaat caagaagccc gaaccccgca
    14041 aggatatctt tgcggaactt ggtctgggcg gcgatgatga caagctcaaa atcctgaagg
    14101 ccaagggcag caaaaacgtt tccacgggcg tggttcacgt ttcctccacg ttcaataaca
    14161 ccgtcgtaac tgtgactgac cagcgcggca atgtcatcgg ctggtcctcc gccggcaaga
    14221 tgggctttaa gggttcccgc aagagcacgg cctatgccgg gcaggtggtg tgccaggacg
    14281 cctgccgcca agccatgggc cacggcttgc gtgaagtgga agtgcgcgta aaggggcccg
    14341 gttccggtcg tgaatccgct gtacgtgccg tgcagacgat cggtattgaa atcacctcca
    14401 tcaaggacgt gacccccatc ccccacaacg gctgccgtcc tccgaaggcc cgccgcgtct
    14461 aattgagaat cttttaccta tatagatcta atatatcatg gctcgttata ccggtccccg
    14521 cgataaagtg tcccgccgtt ttggcgttgc ccttttcggt tccaccaagg ctcttgaaaa
    14581 gcgccccttc cctcccggcc agcatggcat gcgcgccggc cgcaagaaga aatccgacta
    14641 tggcgtgatg cttgctgaaa aacagaaact gcgtttccag tacggtgtgc ttgaaggcca
    14701 gttccgcaag tattatgcag aagccgcccg ccgccgcggc attaccggcg atattctgct
    14761 tcagctcctt gagcttcgtc tggacaatgt tgtgtaccgc ctcggcttca gcaatacccg
    14821 tgccggcgcc cgtcagcttg tttcccacgg ccacatcacc gtgaacggca agaagacgaa
    14881 tatcgcgtcc tactcctgcc gtccgggcga cgtcattgcc gtaggcggca aggcttcttc
    14941 ccagcagctg gttacccgtt cccttgacct gactcaggct actgtggttc ctgactggct
    15001 ggaatgcgac cgtgacaagc tcacgggcaa gattgcccgc gtgccttcca aggaagagat
    15061 tgctcccatc gtcaatgagc agctcatcgt ggaattctac tcccgttaat cttatttcct
    15121 tctggatttg cttcaaaacc ccggttgcct ttcggcggcc ggggttttgg gcattcaggg
    15181 ggggaggggc atggaagagt tgggtgttga gagttaaggg aagctggtat aggatgaaag
    15241 catgacggac gattggaaaa aaagaggcgc agcgcttttc gatatggacg gcacgctcct
    15301 tccctgggat acgcaatata ttttttcctg ttttgtggtg aggcgccatc cttggagacg
    15361 cttgctgatt tttcttttcc tggcctgtat cccgctctat attttgagaa tatgggatga
    15421 gaaccggatg aagagggctt atctcatgta tttgtggggg cttcccgctg aaacggtgcg
    15481 ggaatatgga cggaagtttg ccgagatggc gcaggaatgg atttatccgg agctgaagga
    15541 gcggctggca gggtatcgga agaagggtta tttgtgtctc atggtttccg cttctccatc
    15601 attttacgtg aagcccctgg gcgaactgct gggatttgac gaagttctgg gaacggatgt
    15661 gcttctggag gaacgcatgc cggcaatgcc ggaactgccg aacggtaata ataagggggc
    15721 ggtgaaggtg gagcgtctgc gggagcggaa tgtactgccg gaacatggtg ttctggaaaa
    15781 cgccgttgcc tacagcgaca gtgccgcgga tctgcccatg ctgctttcct gcaggcggag
    15841 ggttctggtg aatccttctc ctgccctgaa agaagacagg cttctggatg gtgcggagtg
    15901 tctgtatccg gccaggcctt ggaagggaag gtttggcaag atatggagaa ttggattttt
    15961 tgtcatgggg ttggtggatg taaataatgt gaaatcaatg acttgctgat ttatcaagag
    16021 aaaattcttt acttttgtga cgaaaatgtt tcacttttct taacaagggg ggaaaaagca
    16081 tttttctttc catgttagca aatcaacaat taatacccta accaagtaat agtcatgcaa
    16141 accaagaaca tcatcagtgt tgcggcagtt gtggcatcct ttgccggagc tgctcttgcg
    16201 ggtactcccg tcaagattgt tgctccgact ccggttcccg ctcctgtggc gacttccag
//
