LOCUS       gnlProkkaDIFEPDJN_110  13919 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DIFEPDJN_110.
ACCESSION   gnlProkkaDIFEPDJN_110
VERSION     gnlProkkaDIFEPDJN_110
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 19:36:41
            Original ID  :: gnl|Prokka|DIFEPDJN_110
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13919
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13919
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4191:4458]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4192..4458
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13919
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13919
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..245
                     /locus_tag="ctg110_1"
                     /transl_table=11
                     /translation="MWLMRKDENRPNGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDL
                     GIGLHDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
     CDS             371..1282
                     /locus_tag="ctg110_2"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(1327..2997)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.6; E-value:
                     3.6e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg110_3"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETNHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(3020..4183)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg110_4"
                     /sec_met_domain="NTP_transf_5 (E-value: 2.5e-46, bitscore:
                     148.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRYFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             complement(4192..4458)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_5"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1.1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 5.2e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(4471..4911)
                     /locus_tag="ctg110_6"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVTVLARDLTERIVFHRIIRRNGDILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             complement(4938..5864)
                     /locus_tag="ctg110_7"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             complement(6111..9689)
                     /locus_tag="ctg110_8"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILTVASNGSKEITASFTASND
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVDAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLTFN
                     TAPTTSTAAPLTLTDKTNTSVSAPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGDTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKANANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTELMKLNITSG
                     TFNGDLKVDASVRTENAQSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTKLA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGYGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVGDGRKEYIVGQTSQENR"
     CDS             complement(9703..9918)
                     /locus_tag="ctg110_9"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             9967..10140
                     /locus_tag="ctg110_10"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEV"
     CDS             complement(10284..10610)
                     /locus_tag="ctg110_11"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             11476..11808
                     /locus_tag="ctg110_12"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFTYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPG
                     ARENLY"
     CDS             12043..12819
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg110_13_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.3; E-value:
                     1.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg110_13"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEVTLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVTKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSLLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        12196..12477
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg110_13_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg110_13_oMT.1"
                     /locus_tag="ctg110_13"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(12894..13742)
                     /locus_tag="ctg110_14"
                     /transl_table=11
                     /translation="MNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSRTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGYT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
ORIGIN
        1 atgtatggct gatgcgtaag gacgaaaatc gcccgaacgg tgagttcacc ttgaagaatt
       61 tcccgaaaca gattgctttg ggtacgggat tcggcttacg ctatgacctg gacttccttg
      121 ttttccgtct ggatttgggt atcgggcttc acgacccgta tgataccgga aagtcgggat
      181 attacaatat tcctaagttc aaggatagta tggcactgca ttttgccatc ggttatccgt
      241 tctaaatgta cgtttttgaa cggatagtgg taaagaatga actaaaactc ccttttgtca
      301 gacataaatt tttgtacatt tgcaaccgtt atcaactatg atacactaac ctttttaaat
      361 aataactaat atgaaaccaa ctttattctt attggcagcc ggtatgggca gccgttatgg
      421 tggcttgaaa caattggacg gattgggacc gaatggcgaa actatcatgg attattctat
      481 ttacgatgcc atcaatgccg gttttggcaa gctcgttttc gtaatccgta aagattttga
      541 acaggacttc cgcgacaaga ttatttccaa atacgaaggc catattccct gcgaactggt
      601 attccagtcc atagatgacc ttcctgaagg cttcacctgc cccgaaggcc gtaccaaacc
      661 ttggggaacc aaccatgctg taatgatggg tgccgatgta ataaaggaac cgtttgctgt
      721 tatcaattgc gacgatttct acggtcgtga ctccttccag gtaatgggca aattccttgc
      781 agcccttccc gaaggctcca aaaacgtata ttccatggta ggcttccgca tcggcaatac
      841 gttgagcgag agcggtaccg tatcccgtgg attgtgtgga acggatgcga acaacctgct
      901 gacttccgta gtggaacgca ccaagattca gcgtatggat ggcgaggtga agtacatcga
      961 cgataacggt gaatggactg ccactcccga gacgactccg gtcagcatga acttctgggg
     1021 tttcactccc gattattttg cttacagtgc agagtttttc aagagtttct tgagcgaccc
     1081 gaagaatatg gagaacctga aaagcgaatt cttcatcccg ctgatggtag ataagttgat
     1141 taacgatggc actgctacct gcgaagtgct tgatacaacc agcaagtggt tcggtgtgac
     1201 ttatcccgaa gaccgtcaga gtgtagtcga caagattcag gctttggtgg atgcgggcga
     1261 gtatcctgcg aagctgttct gagtttgtta accaaaggca gatacccgtt ggggcttatt
     1321 ctctgattat aatcggacaa tagattcgca tgcctccgct actgccggat ggtgggtgac
     1381 gaagatacat gttttgcctg cgcagtctct gcgcaggttt tttattaaca gccgttccgt
     1441 gtcggggtcg agggcagaag tggcttcatc taaaagaaga atgtttccgg ggcgtagcag
     1501 agcgcgggca atggcgatgc gttgggcttg tccttcactg agtccaccac ctcgttcgct
     1561 gagtggggag tctacgccgt cgggaaggtg gaagacgaag tcggcggtgg cggtttgcag
     1621 ggcttgatat atggcttctt gagaagcttg tgggtttccc atcagcaggt tgtcacggat
     1681 agttccgctg aaaagggtat tgccttgcgg gacatatacg aagttcttgc gggtttgcgg
     1741 agagacggta tgattggttt caagtggatg tttggcgggt atcaagagta tctgtccctc
     1801 ttgtggcgtt gccagtgcca acaatagccg gatgagcgtt gtctttcctt ttcctgtttc
     1861 tccgactata gctatgcagc taccggcggg gaaacggcag gagaagcggc tgaataccgg
     1921 acggtcatcg ggagtgtagc gaaaagtcac gtctttcagt tccagttccg gggtagaggc
     1981 gaggaatatg ctgtcaccat ccgcttctgc cggcagtctt tccaattcca atagccggtc
     2041 tatggcggta agggcattga ctacggaagg tatcaggcgt gagaggtcga acacgggacg
     2101 ctggactttt cctaccaatt gcaaaaaggc ggtcatcgtt ccgaaggtga tacagcctgc
     2161 gctgaggtga acggctcccc aaagaaaagc cgtgaggtat ccgccggaaa aggcaagggc
     2221 cactaacatg tgggcagaaa gcgagaaacg ggtacgtccc atgacttggc tgtggagcat
     2281 gtcttgcaag tcatcgagtt tgtccagatg ccgttcgcct tgttccaatg ttttaatcac
     2341 tatgcgatgt tgcaggctct cttgtatgac ggactggatg cgaccgtcac tgttccgaat
     2401 atcatgtgta tagcgtttca ttcgtcgcat atagaaacgg ctgcctgata gaaagacggg
     2461 caggatggca acaatcagcc atggcagtga agggtctaaa aagtagaaga atagaaaggc
     2521 tgccagcagt tgtatactcg tgacgatgaa tgccgggaca gaagaggtga gcaatgtgac
     2581 gatggcggtg gtgtcttgtt ctacccggtt cactacgtct ccggtatgga aacgctccaa
     2641 ttcgttccag cggctttgca gtaagcgcga gaagaggcgg tggcgaaggg cgttgcccgt
     2701 ctctatctgc atacgggtac ttatccaagt gtcagcagct ccgcacagta attgggcagt
     2761 cagcaggaca acggtgagaa cggcgatatg cgtcaggttg tcgtctgtta ttccggtagc
     2821 ggtgtctatc acccgtttgg ttgcatagat aaaggctagg gcaaaggcca cgcccagaat
     2881 gccggtgagg caacttagca ggatacgtcc gcgttgttcg gcagatacct ctcgaatata
     2941 cctaagtttt tcacgtctgt cctttttcac ttttttgtcc ttctgttgct ttttcattcc
     3001 ttttattttc cgggttcttt tatttctttg tccttgcttt cttgtctttt actccttttg
     3061 atcggtttat ttgtatagct atcgttcccc ctatcagagt cacgggatac cagagtgctt
     3121 cgtacggtgc aaattgacgc agttcgttgc agcgtcgggt ggcgcggcag aaggtgtacc
     3181 actttcctgc ccaatatcct ttggggcgtg gcttgatgcg gttatcatgt tgcccgaagt
     3241 taccggtaga caggatgtct tccaataatt gttctcctat ctgcttggtg ccttccaagg
     3301 ggaaaggaag ccggttggcg ggcaatccca gtcgggtgac ggcaatgtag ccgaatgctt
     3361 gtgcggcatg caatagtccg aggtcctgca actggcgaag cagggtggtg gcatctattt
     3421 ctttgtggcg attggcaagc agacaagtcc agtcgcatag ctggcgcagg ccgattccgc
     3481 tgttcaggaa atgtacaaag gcatgcagga agatataaag tgcattgaag gtggccggag
     3541 gtatggcgat actgacggcc ttcgagtcct ctttcccggt ttcggagaat agggcatagt
     3601 ctgtttcctg cgggtaccat tttctgataa tctgctgaaa gtaccggttg gcaagcggac
     3661 tgttcagccg gaggatgatg cggtggttct cgatgtgtac tcctttcaaa ctgtagctag
     3721 catgcttgtc ggacgcttct ccctcgacta tggcgccttg ttgcagcagg aggcggttgg
     3781 ctatgggttg cccttgtttt cctaaataga tgtcgatgtc tccgcattgc cggtgcaagg
     3841 gagtgcggta gttggtgccg atgccttgcc ctttcagcag tacgggatgc agcccggctt
     3901 cccggtaaag ggtattgagt tcgggcagaa gctggttgag gcgtttgttg gcttgttcta
     3961 tctgtgcagt ccgggcagcc catttcagat agaggacgcg tggagggcgc agttcggccg
     4021 gcagactgct tatgccgtca aaagtcagtg caagcagggc ttgtgagttt gccatgcggt
     4081 acacggtttc ccagtcgtcc ggcgagaccg accggaagag ttgtcggtct gccggagtgc
     4141 cccacaggcc ggagcgtacc aatgaaaaga aagcgtgttg catatccgtc cttattctat
     4201 gattccttcg cggtcaaggg agtcgataaa cttctgcgca tcgcgacggg ccgattcgtt
     4261 atctacatca tagcggctgg tcagggcttc tgtcacgctg tctgtatcga actctttgtt
     4321 ttctatctct tgccaaagca tggcggaagt ttggttcagg ctgatgactt tgctgaagtc
     4381 cacgttcgac gagccgtctt gcatgatgat gtagtcatcg cctatccggt gcaggataaa
     4441 tccttgtttg attttcatgg ttattttgtt ttatattctt ctgaacaggg cgagcagcca
     4501 gcggcgagcg gggtttagct tcatccacca gtaggagtag agcttccaga ctttgccgtc
     4561 ggcggtgtac cgtttgtctt ttcgcatggc ttcggtcatg acgcccatta cccgtccgat
     4621 gtcggtttct tcggtctggg cgaggttgcc gtcgccttgc aggatgagta tgtctccgtt
     4681 ccgacggatg atgcggtgaa agacgatgcg ttccgtcagg tcgcgtgcca gtacggtgac
     4741 gcccggttgc agctgttctg tggtgaaatc gcccagtgtc acccggtcac ggcggtccac
     4801 taagaaagga ttcatgctgt tgccccgcac ggtgatggtt actgtatgtc cctctttgat
     4861 gagacgcgcc acttcgggaa gcaatatctc gttgggaatg cttttcttca tcggctgttc
     4921 agttcatcat tcataactta tccttctacc gtctttctgc aaagttccgt cgcttcacgg
     4981 tcgggtaggc atttcagatg atagacgggt gccagcgtgg caagttccgt cacagtggcg
     5041 acaatggcgt tatagatttc cttgttctgc tttaggcaag agcaggaggg gaggagggtg
     5101 gcgaaagcat gtgctgctct ctcttgctct atttcattct gcggtgcttg ttccaagcgg
     5161 acgaaggcgc ctacggtcat ggattctttc cgatagcaag gtgtctttcc gctccacgga
     5221 gaaccgaaaa cagtggcttg cttgccgagg ctgtccacat gtactatcgg attgtcatcg
     5281 ttcagtagat ggcagtccga gaactgttgc agccagagcc cggtgtgcgt acttttgccc
     5341 gtgccgcttt tccctaagaa gaggtagcct ttgcctgttt cagtagcgac aaccgaggca
     5401 tgcatcagca gtgtatggtg gcgggcggca ttgaaggcat agagcatcat caagaagttg
     5461 ttcagtacga agttcgtttc gttttccgga gccggtgttt ctgtcctgca ggccggtagg
     5521 tggatgaagc attgcctgaa gttatcgttg cactccatcc aatagttttt cccgcttttc
     5581 cgtggggtga tggatacaag gtgtgagctg tggggcaaag ggcgaatgat gcaatcggca
     5641 tcttcccagt tgaaacatat atcatcggga gttttcgcta tggttcgttt tgtcgttgtt
     5701 tcgtcatcgt ctatctctgt ttcaaagatt actttttgcg tcgtgtctat tgtcgtgatg
     5761 aacggaatca gtgaaggcag cgccttgaat atattgaagt cggaaggttt caccatgcga
     5821 aaggtgtgcg gtcctacttg ataatccaat atctgtattc tcatatgttt tgattgttag
     5881 ttgttattca tgatactttg ggctactcag aaaaataatg aatgtttgtg tgaatgagga
     5941 agatttgaga gatttttcaa ctgtcttgtt gtcattcttt agacgcggag gacgcagatc
     6001 tataaaagaa aatccgctgt ccgccgcatc taaaagatag taataaggcg attccgatat
     6061 ctcttcgttt ggtttgcgag gatatattgc ttcctttctt agaatttggc ttatcggttc
     6121 tcctgacttg tttggccaac aatatattct ttcctcccat caccgacttt gtgggctgct
     6181 gtatatacac tgccgtcacg ggtaacctcg tagcctgtta ccaaatagga ctcattgtcg
     6241 tccatattcg gatttgccgg gttgaaattg atgaacgttc caccggacac ctggatgctg
     6301 gcagtgttct tgtctgtatt ctttaagttc agtacccagt atctgccatc cgtgtcgttg
     6361 ttgggtgtac catatttgcc ggattcaaat gttcctccat agatattgat tttcccattc
     6421 tctcttgcat aaatcaggtc tatctgggtg ttcagtttct gggtgttata gtaagaacca
     6481 ccatgaatat ttactgtccc gtatcctcgg gcttcaatta ccatgcgata accatcgtct
     6541 ttcgctgtag cagatgcatc gcacttcaca ttgccgttgc ctgaaatgtt tagtgttccg
     6601 ttctgtacag taaagatttg tgtgaaagga gtggcatcag ctgtttctga ggaattgatg
     6661 atgtcgtggc cattcaggtt taagtttgcc gttgcgtttg cagcattcaa tatgtagcct
     6721 gtggcaagct tcgtcttggc gatgttgata tttgagagaa gttttatatc cacagttgcg
     6781 ttggttgcca tgtacttcag tacgcttggg tcggagaatg tacctccgga aacagagatg
     6841 atactttggg cattttcggt tctcacggat gcatctacct ttaagtcacc gttgaaagta
     6901 ccgcttgtga tattcagctt cataagttcg gtatttcctg cactcttgga aatttccact
     6961 tttccattga tgacgctcgt accgcttacc gtaaccgtga ctccagcagt gtactttgca
     7021 tagccgcata cgtcgaatgc aaattgattc gcattgcttc ctgcgttgat agtggtattg
     7081 ttgatgctta tgttgccaca attgttgctt actacgtatt gggcatttgt gtcttctact
     7141 gtcatattat ctaatgtcag gttgcagtag ttctgaatca tgattttgtt gttgtcactc
     7201 ttcagcgttc cgttcttgaa agtaacgttt gaaccttcga gtaattgaca gctgttcgtt
     7261 tcggtgccgg tggaacctac ggtcgggtca gcaagtgtaa gaatcttgcc gcctaagtcc
     7321 atcgtcaagg tttgtccgct tgtggtcttg aatcccgggc aggtcttgtc ggcggtcaac
     7381 tttatgttca catttgcatt tgccttcatg tacttcagcg cgcttgggtc ggagaatgta
     7441 ccgccggtaa cgttgatgac cggtgtataa gtggtgcctt ctgtgatgag tgactttgct
     7501 tcggcaatca gtgtaccgcc tttgatgttt actgtggcaa tgccatatgc tccacttacg
     7561 ttgatggcgg cgcagtccag tcctccggta ccgtcgcccc agttgccggt gctacctgtg
     7621 cctttactgg taatcaaggc tgtaccttcc acattcagag tgcctcgttg gatgcataca
     7681 cctcctgcgg caccataaac cttgccgcca ctgatggtcg ttgtgccgga ttggggcaga
     7741 tagactgcat agtcagcagt agaaatgagt tctccgtctg tgatgttgat gatggagttc
     7801 tgcgtcttgt aattgccgtt gcctgccact gcaaaccatc cggcttctat cttgccgcct
     7861 gtcatggtga agtctccacc gtccgtcact ccgacgccat attggccgtt actgtccgga
     7921 gtctctctga ctgcactgat gttgccgctt tccatggtca tggaggcatc ttcaccggct
     7981 atttcaatca gactgccatt ataagaagcc gctgtataat cctggctggc aactatcttg
     8041 cctttcttct cggtagagct gtccttcagt gtcatcttgc ccaagacgat gattttgcct
     8101 gttgcgctgt tgtcggcagt cagtgtatat ccgttcaagt caagaaccac ggactttccg
     8161 gcgggtacac tgacgctttg ccctgtgatg tcggcatcgg cggacaattt aaaatcttcg
     8221 ccgttggcga aagcggtctt taggactgcc acgtcggatt gaactacaaa tttgctgtcg
     8281 attgttgccg gaagtgatgc ttcagttcct tttattatat agattgtggt atcgccggca
     8341 tcgtgtacca attgttctac ctttccatat atcttcaagt taccgccttt tacagtcagc
     8401 ttctttacgg tgacgcctgc attgataatc aatgtctgct gggcggtagt ggcagtcact
     8461 tcattgtaag tggctttatt gcctactgct gccaatgtaa cggtggtgct tggcatggtg
     8521 atggctacag aaggagcttc ttgctctgct gtggtttccg gtacagccaa ggatacactg
     8581 ttggtggcag tggcggcggg agcacttacg ctggtattgg tcttgtcggt cagcgtcaac
     8641 ggagcggcag tactggtcgt tggggctgta ttgaacgtca ggttgatgtc cgagttctgt
     8701 aaaaccggga tggcgatgcc gtcgttgctg ccagaagtgg tattgaagct gccgctgact
     8761 gcaatgtcgg ttacggttgc tgctgtcggt gcttcttgtg ggagattttt tgaatcagct
     8821 aaagctgtac taagcgcact gggggttgta gcatctacaa caacgcaatc caaaggaggt
     8881 actaccaata tgtctcttct ccctaagatt ttgtcattaa gcgtcttggt aaaatatacc
     8941 ttgtcgcttc cattcgtcag ttgggcagtg atggaactat aagtacctgt gggcaaagga
     9001 atgtagaagt tgcgcgattt tatatcgttt gaagcagtga aggaggcagt gatttccttg
     9061 cttccattgc ttgctaccgt cagtatcggg tctgctgcgg ttaagtctac cgtacaagta
     9121 cctgcaatgt tattggaggc aataatcttg aaagtagtgg cctctgccgg aatcttgttg
     9181 acggtcagtt ttatcatggc tgccatgtgc ttgaaggaca gagcgctcag attgtcggga
     9241 tttgtcacct tggcatacat cgggccattg ctgctgccgt tataatttgt aagcgtggca
     9301 ggtagagtca tggtcaatgt attgccgctt acgctcatgt tttgttggta aggatagatg
     9361 gagaatacag ccgtttctcc gcttggcttg ctgccgttga aagtggcgga agtttgacca
     9421 gcaccgcttg catattctaa ttttgtattg ctataattac tttctgcatt actacagaac
     9481 aaccctaggg catcggtatc ttgccataga atcttgtatt catcgtttac ggtagtacgg
     9541 gtgtcggtac ctgcgccttc aaacgttgcg ttaacggtga tgtttccttt ccacccgctg
     9601 ttttcaaatt cctcttggct gcaactgaat gcggtcaagg cagcagttgc catgcaggca
     9661 acttgcataa ggtttcttaa tttcatcata atgaagtccc ccttagtttt ctacggttaa
     9721 gatgtcattg attaggtctt ccaagtcgct gctggatgcc gaattgtagc tatgggtaga
     9781 ggtgctgccc gaataggagc gcgtaatggg atggtaaggt tcgccgcttg ttgcaatgac
     9841 tccttcattc tccattttga taacttcgat agacggagtg atgtatgctt ctctaccgtc
     9901 tggtgtgttc tgtttcatat acacaaatta tttaaaggtt aaacaataaa aaaaacgtga
     9961 gtaactatgt ttgtatatcc tttattcagg ccttcgcatt gccctttccc tggatataca
    10021 acagtcactc acgtcgtttg tgtatatact atcccccctg atgggagaaa accatataaa
    10081 catagacgtg agcatccttg ttgttatctt cagggaaatt ttcaaagttg cgaagtttga
    10141 ataaagaaga taatttcaat aatgctctta ctaatatgta aataaaccca ctacgctata
    10201 gcggatttgt gacaaagata attgtttttt gtttaagtgt atctatgttt ctctattttt
    10261 tttgggaaag gctcacgtct ctttcattta taggagttag gagagttatc acttctaact
    10321 cccgataact ccttcaaata tttagtaact gtctgcattg tctttgagga tgtttttctg
    10381 aggagcatag cggctatgtg gcgaataaag aggggaagac agaccgaaaa gaagctgaat
    10441 aaaatctttt taagcaaaat taaaacagag atttgatata ctttaaacag aacaccctgc
    10501 aaactccggc ttgctctgtc cggcagtttg cagggtggct gcttggtttt ctcgcgtgta
    10561 cgtagctcct tatgccacga acggaagtcg atgccatagc aatttttcat aataagactt
    10621 tccatatttt tgcaaatgtc cgtactgcct ttggctgaaa caatttatat aagtaattga
    10681 agtttcgtaa gtgagtatgc ctgctgataa atgggaattt atcgcacaga gcgcgaagcc
    10741 tgctctcata acctatggag agcacgagtg aaagcttgtg gatttttatc taaaacatag
    10801 gtattccttt actcttctcc ctttgtttgt ctgctgtggc atagggaatt tatgacgcct
    10861 aacggccatg aacaaccctg ctttcgacca taaagcaatc gtttgacgac cgtaagcaga
    10921 gttgttcatg gccgttaggc gtcactaact ccagagctat tacagatgaa gtacgtagcc
    10981 cgaacctatt gcgcacaagg cgcaaacgta ttatacaacg gtgtaaaaga cattagagtg
    11041 cattattcat agtcggcctt tgattcccga taactcctac tatgctccta cagtccaact
    11101 ccatatccgt tgacttcaca gtaaggacaa gcccgaaaat gcaggaaaac cgaacctgcc
    11161 gattcatgta atctgcatgc agtattatgc taggggatag cagcttactg caaaactcag
    11221 gcgtttcagg caggtggaag caaattttgc ttccaccttt tcaggttgct tccatcgcag
    11281 ggcaaatgcc gatggacagg gggatgcagg aggtgggtgg aagtgtggaa gcaaagtgat
    11341 ggaaaattaa tttggcattc acacaataat aaccgtatat ttgtagcatg gctgtctgcc
    11401 tcctcttaaa ttcagataaa gaggaggtag acaaatgctt gctatgagaa acacataaat
    11461 ggttataacc aagtgatgaa acaattaatt gcatgttgcg gactggattg cgaaaattgc
    11521 gccgcccgta tagccactgt caataatgac gatgagctga gagagaaaac cgccaaagag
    11581 tggagtgtgc tgaacaatac gccggaaatt acggcggaaa ccatccattg tatggggtgc
    11641 cgtgcagacg gggtgaagtt tacctattgc agcgattatt gtgctatccg caaatgtgtg
    11701 tacgaaaaag gtttcaatac ttgtggcgac tgtaaggaac tggatacttg ccaggtggta
    11761 ggtgcggttc ttcagcatgc gcccggtgca agggaaaatc tttattaacc gtaaaatctt
    11821 tgattaaata aaatattgct tatctttgca gtatgacaaa gacatttaaa tcggatttgg
    11881 ttttgtaaac aatctgtgtt ccatgcacag attgtcccct ttcgtttact ttcggataac
    11941 ttctttcgag agtgtttttc tattgttata attcaagttt aatccgcata ttatgctgaa
    12001 ggtgttgtga tactttccgt atatgcaaaa tatagtaaga aaatgagtaa cgaaaataaa
    12061 actatccacg atttcgaatt taatttaatc tgtgactttt tctccaatat ggaacggcaa
    12121 ggccctggca gtcctgaagt gacgttgaag gcattgagct ttgtagacgg tcttaccgat
    12181 gaatccctta ttgccgatat cggttgtgga acgggtggtc agacaatggt attggctggc
    12241 catgttccgg gacagattac cggaattgac cttttccccg gctttattga catcttcaac
    12301 cgtaatgcaa ggcagttggg cttgcaggac agagtaaaag gaattgtcgg ttcaatggat
    12361 gccctccctt tcggtgagga ggagctggat atgatttggt gtgaaggtgc tatctataac
    12421 atcggctttg aacgtggctt gaaggagtgg cgtaaatatc tgaaaccggg agggtatatt
    12481 gccgtatccg agagttcatg gtttacggac gaacgtcctg cggaaatcaa tgacttctgg
    12541 atggacgcct attctgaaat ggatacactt cccaatcagg tgaccaagtt gtacaaggca
    12601 ggttatcttc ccgttgctac attcattttg ccggagaatt gctggacaga gcattacttt
    12661 gcttcaaagg ttgcggctca ggagattttc cgtaagaaat atgccggtaa taaaattgcc
    12721 gaagagttca gcttactcca aatgattgag gatgaactgt acggcaagta taaggaattt
    12781 tacggttatg tgttctttat tgccaagaag gtaggctgat gacggacttc tcttattgag
    12841 gaatgcgggt attctcagga cagaatatcc gcattttggg ttttgagtag attttattgt
    12901 tttgaggatg tacggaactt ctgaggaggt attcccgtat gacgtttaaa gaatttgttg
    12961 aagaaggccg cattattaaa acctagactc acggctatat cctttatcgg agtgttggcg
    13021 gtacaaagtt gtgctttggc atccatgatg atagtattgt tgatgatttc catggctgta
    13081 tatcctgatt cctttttgac aaggcggcaa agagctgccg gtctcatatt cattttcaat
    13141 gcataatagg acacttgatg ctcccggaca tagtctgtgt gtaccaatcg gataaaaatg
    13201 cggtattggt tgaaatgcct gctgcccgga gtctctttta ttctagggcg ttccggacag
    13261 agttcggata taccttgtaa cagataggtc agtagagttt gcaatgaaac tagacttgag
    13321 gggctttctg ttctttggta gaggtgtgac aaataggtca tgaactcggc ataaagctgg
    13381 aagtccgttc tcgatagagg aaaaatatag tgtttgccta taatgtgaaa cttatccatc
    13441 atgaccttgc cggcccctga actctggata agttgttggg aaaatatgac gacatatatt
    13501 tcagcatcgt ctgacgtgtg tagcaattgt acgaaggtct cgggaggaat aactaggagg
    13561 gcgttagctt caaccctgaa ttgagtatgg tttatgatag ttttcagaac tcctttggtg
    13621 catagagcga agatactggc cttggtgtgg tatggctttt ccactagcgg attcagttca
    13681 ttggttgtga tatgattgca ggcaatgaac tcgtcattta tattgaattc ggatatattc
    13741 atgttggaga ttttaagacg caaaaatggg ggataataat gtataaatga cagaggtaac
    13801 agttaaaatc aatattacgc tcaacttatc tctgttaaat aaggtaaagt tgtgaataat
    13861 agaatataag taactaatca aaattaagca gcataatggc taaagttaat attcagtcg
//
