LOCUS       c00005_gnlPro..        16868 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDGIIJCL_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:18:33
            Original ID  :: gnl|Prokka|HDGIIJCL_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 174776
            Orig. end    :: 191644
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16868
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[184776:188262]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13486
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16868
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16868
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(57..1805)
                     /locus_tag="ctg5_106"
                     /transl_table=11
                     /translation="VGNNIQILSPENQTSIVTRETKDGIVCGQAVHQREFGISKGLFWS
                     PAGSALAFYRMDESMVTDYPIVNIDARQAKAEPVKYPMAGMKSHEVTVGVYNLSTGETV
                     WLETGTPKEKFLTNIAWSPDEKSIYIAELNREQNEMNLVRYSALTGKKEAVLFTETNEH
                     YVEPQYPVLFLPNDPGKFIWQSQKDGYNHLYLYDTTGKQLKQLTQGEWVVTQVIGFDAK
                     GENLFITSTQPHIQSSFNYGTPMNVNGWKLNLKKGETSLLTPNAALESVHNLSVSASGK
                     YAIDSYDAPKIPRIINLIRTKDGKEIKNLLTARDPYKGYTLPEIEAGTIKSADGTTDLH
                     FRLVKPVGLDENKKYPTIVYVYGGPHSQLVTGGWQNGVRGWDIYMAQRGYVVFTVDNRG
                     TSNRGFAFESVIHRNLGVNEMADQMKGVEYLKSLPYVDADRIGVHGWSYGGFMTTNLIL
                     THPDVFKVGVAGGPVIDWSNYEIMYGERYMDRPQDNPEGYKNANLKLKAGNLKGHLLQI
                     HGDIDPVVVWQHSLGFLKACVDADTYPDYFVYPRHEHNVTGKDRPHLYEKITRYFDDYL
                     KNTNKE"
     CDS             complement(2264..3841)
                     /locus_tag="ctg5_107"
                     /transl_table=11
                     /translation="MVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDKEVLYRAN
                     FCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSEDFNHSKF
                     VAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESLHKRGYRV
                     EQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGIHRKEFAF
                     EKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIEIAQKNIRSAGLAKYVELKTM
                     PFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWILSYKDECF
                     DKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSASRPRPSFP
                     EKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERGDGRPARK
                     QFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRPFKKPFRR
                     EDNDDFED"
     CDS             complement(3888..4787)
                     /locus_tag="ctg5_108"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     LIFSQAEKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVITQNKVTK"
     CDS             complement(4846..5316)
                     /locus_tag="ctg5_109"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIADKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             complement(5337..5813)
                     /locus_tag="ctg5_110"
                     /transl_table=11
                     /translation="MKTLVHTEKEHIEEIIRSCDVCFVGLADTDGTPYVIPMNFGYRNG
                     VIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHPEVACSYRMRSKSVIAWGKVRFE
                     EDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLVDLDEVTCKEFGAPHKKY"
     CDS             6544..8367
                     /locus_tag="ctg5_111"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLGQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFADWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARMLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHLEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRETVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDALGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVKGFVPVTNIYSETHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVISVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             complement(8371..8610)
                     /locus_tag="ctg5_112"
                     /transl_table=11
                     /translation="MKGNGSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEIL
                     TSLRDSQPVYGESHLSKHKIHYFTIGATVTALFW"
     CDS             complement(8625..9287)
                     /locus_tag="ctg5_113"
                     /transl_table=11
                     /translation="MAATIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVL
                     AGAGIGILSTELGYFLADLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIE
                     VGKNIRLSSPGATNVSVKGGYFFNPYFGIGGEITALASPIAFDMSLYTGTTPSTKYDIT
                     RVHADPTGVFTFTAGPYFSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKPPHTEP"
     CDS             complement(9232..9762)
                     /locus_tag="ctg5_114"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVCAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVXXXXAPDDRIERFFGNDHGRYRQQHEIYDQTRTPRRLKEQLIPFGTHGNRFHGCYH
                     HAPGIWSDPQPVI"
     CDS             10001..10726
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_115"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-75, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             10760..12703
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_116"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.1e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9e-38, bitscore:
                     122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             12731..13486
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_117"
                     /sec_met_domain="Fer2_3 (E-value: 8.1e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.7e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(13785..14630)
                     /locus_tag="ctg5_118"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             14976..16085
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_119"
                     /sec_met_domain="Radical_SAM (E-value: 6.2e-09, bitscore:
                     29.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCFYAKDMDKKEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREE
                     LPEIIEMFYKNNEIKDVNIPTNGLKPDRIVAWVKQIRRNCPELNINLSLSLDGFGDTHD
                     IQRGVPGNFYKAMGTLKLIEKNFADDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLS
                     NHIIEAARGMTRDDGVKVLTEPTLRALQDKVVPIYNVYGERMAEETGGFRKPIARFFYL
                     GFIRTLYNVRATNIDHPTPWGMDCTAGETTLVIDYDGRFRACELREPLGNVKDYDCNIA
                     KIMESDAMKQEIAAIGHGDKANCWCTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRP
                     LNISEELLQSIERKYALDEQKLVELGVRN"
     CDS             16263..16847
                     /locus_tag="ctg5_120"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
ORIGIN
        1 cccgccttat aactagcttt aacacacccc ttatcccctc tcaagagggg aaacagttac
       61 tctttgttcg tatttttcaa gtagtcatcg aaataccgtg ttatcttctc gtagagatgc
      121 gggcggtctt tgcctgtcac gttgtgctcg tggcgggggt agacgaaata atcgggatag
      181 gtatctgcat ccacgcaggc tttcaggaag cccaggctat gttgccatac cactaccggg
      241 tcgatgtcgc cgtgtatctg gagaagatgg cctttcaggt tgcctgcctt cagcttcagg
      301 ttggcgttct tatacccttc cggattatcc tgcggacggt ccatataacg ctctccgtac
      361 atgatttcgt agttgctcca gtcgatcacc ggaccgccgg caacaccgac tttgaaaaca
      421 tcgggatgcg tcaggatcag gttggtcgtc atgaagccgc cgtagctcca tccgtgcaca
      481 ccgatacggt cggcatccac gtaaggaagc gatttcaggt attccacgcc tttcatctgg
      541 tcggccatct cgttgacacc caagttgcgg tggatcacgc tttcgaaagc gaatccccgg
      601 ttagatgtgc cgcggttgtc gaccgtgaaa accacgtagc cgcgttgtgc catatagata
      661 tcccagcctc ttacgccgtt ctgccagccg cccgttacca gttgtgagtg ggggccgccg
      721 tagacgtaga cgatggtcgg gtatttcttg ttctcatcca gtccgacagg tttgaccagg
      781 cggaaatgca ggtcggttgt accgtcggca gattttatgg taccagcttc tatttccggc
      841 agtgtgtagc ctttgtatgg gtcccgggcg gtcaggaggt ttttgatctc cttgccgtct
      901 ttggtccgga tcaggttgat gatgcgcggg attttcggag cgtcgtaact gtcgatcgca
      961 tatttgccgg aggcgctgac cgaaaggtta tgtacacttt ccagggcggc attcggtgtc
     1021 agcagggatg tctccccctt cttcagattc agcttccagc cgtttacatt catcggagtg
     1081 ccgtaattga acgaactctg tatgtgcggt tgggtggaag tgataaacag gttctcgcct
     1141 ttggcgtcga aaccgattac ttgggtgact acccattctc cctgtgtcag ttgtttcagt
     1201 tgtttaccgg tggtgtcata cagatacagg tggttgtatc cgtctttctg gctttgccag
     1261 atgaatttgc cgggatcgtt cgggaggaag agtacaggat attgcggttc aacgtaatgt
     1321 tcgttcgttt ctgtgaaaag gacggcttct ttcttgccgg tcagggcaga atagcgaacc
     1381 aggttcatct cattctgttc gcggttcagt tcggcaatat agatgctctt ttcatccggg
     1441 ctccaggcga tgttggtaag gaacttttct ttcggggttc cggtttccag ccagacggtt
     1501 tcgcctgtcg agaggttgta cacaccgact gttacctcat ggctcttcat gccggccatc
     1561 ggatatttaa ccggttcggc ttttgcctgg cgggcatcga tattgacgat aggatagtct
     1621 gtgaccatgc tctcgtccat ccggtagaaa gccagggcgg aacctgccgg tgaccagaac
     1681 agtcctttgc tgatgccgaa ttcacgttga tggactgcct gtccgcatac gattccgtct
     1741 tttgtttcac gtgtaacaat actcgtctga ttctccggtg aaagaatctg tatgttgttc
     1801 cccaccgtga atgccaggca gttattggcc ggacagaagt tatagttcga tcctttgctg
     1861 tccagctgat aattgccaat tatcttgttt tcggcaaaat tgtaatgcag gcggtggcct
     1921 ttactggtaa aagccagtac cggctggtcc ttatagggaa ccgaaannnn nnnnnncggg
     1981 caggctgcct accgtcggaa gtccggctgc cgaaagcgcc tcattgagtc ggctgcgtgt
     2041 aaaggcaacc tgctctttct tttcgggtac gccgcatatc atactgtctc ctttgacata
     2101 caggtaagtg tccccacacc attgtagctg tttgagactg gccgggacga acttattgtg
     2161 tgtcttccct cccggaagca ggtcgtgtaa tgtgagttgt ttgtcctgtg ccatcagcgt
     2221 catggatgta gataaagcga acacgcaaag aaccaggaag tgtttaatct tcaaagtcat
     2281 cgttgtcttc tcttctgaat ggtttcttga atggacggcc ttctccgcgt tttctgtctc
     2341 cgaagttctt tctgttttta gagaacctgt cgtcttcgtc tttgtaacgc attttgacgg
     2401 ggcgtttttc accggctttg tgcagaatcg ggcgaaccgg gcgttcacca cgttcgcctc
     2461 cgaactgttt gcgggcagga cggccgtcac cgcgttcttc accgaagaaa cgttttcccg
     2521 gtgctgcgga tgtacgttcg ttttcgtctt cactgtgagc cgcggcaaaa cgacggtcgg
     2581 ggcgatccat gcgatcggtc ttgaagttcg ggcgacctgc aggacgggtg tcatatcttt
     2641 tttcagggaa tgagggtctc ggacgtgagg cggaatcttc cgttctttcc gcgccttcct
     2701 cgttcaatgc tttcttatag tctttgttct ttccttcaaa tatttcgtag caacggtatt
     2761 cgcagtcgag cgagccgttg attagcttca tccgttcgct gggacgcagg ccgatcttgt
     2821 cgaagcattc gtctttgtag ctgagtatcc atactttata tccggtaaac acatgtttga
     2881 cgcgttcgcc gatcatatta taaagtccca gcaggtcgcg ggaggagata cgttcgccat
     2941 aaggcgggtt ggttaccagg atacccggtt gcggtgcttc cgtatattgc tggaaaggca
     3001 tcgttttcag ttcgacgtat ttggccaggc ctgcgctacg gatattcttc tgggcgatct
     3061 cgatagcggc cgggttgata tccgaaccgt agcatttgaa agtgaattcg cgttcctggc
     3121 tttcgtcgtt atagatgcgg tcgaacagtt cctggtcgaa gtcgatccat ttctcgaaag
     3181 cgaactcctt gcggtggata cccggggcga tgttcagggc gatcatagcc gcttcgatca
     3241 gcagcgtacc ggaaccgcac atcgggtcga cgaaattgga ttcgcctttc cagcctgtct
     3301 tcaggatcat accggcagcc agcacttcgt tcagcggtgc ttcggtctgt tccacgcggt
     3361 atccgcgttt gtgaaggctc tcgcccgaac tgtcgataga caaggtacaa tcgttgtgcg
     3421 agatatgtat attgatgtat aagtcgggat tgttcacacg tacggaagga cgtttgttgt
     3481 gcttctccat aaagtagtca acgatcgcat cttttgtacg gtaagccacg aatttagagt
     3541 gattgaaatc ttctgaatag atcacggagt cgatcgcgaa cgtcttgtcc agtgacatat
     3601 agttttccca tacgactttt ttcacttcct tataaaccgt atcggcatct tttgccttga
     3661 aatgatagat cggtttcagg atgcgtaagg cggtgcggca acagaagttg gctctgtaaa
     3721 gcacttcttt atctcctgtg aaggatacca tccggcggcc aatttctata tcgttggcgc
     3781 ctatagctaa taactcaccg gccagtattt cttctaaccc gtacagggtt ttggccacca
     3841 tttcaaatgt ctcgttattc atttgcgtgc gttgtaagaa aagatattta tttagttact
     3901 ttattttgtg taatgacagc accgggggga acatctccgg tgatccagac gttgccgcat
     3961 atcgtggcac ctttgccgac ccgtattttc cccaatagcg tcgcgttgga gtagacggtc
     4021 acattgtctt ccaggatggg atggcggggg acaccgcgga tcgcgttccc gttctcatcg
     4081 ggtggtagct tctctccggc aaggctgaca ccctggaaga tgcgtacgtt attcccgatc
     4141 acactggttt cgccgatcac ggtacccgta ccgtggtcga tagagaaata atgtcctatc
     4201 tgagctcccg gatgaatgtc gataccggtt tcggaatgag ccatttcggt gatcatccgg
     4261 ggtataaaag gaacgcccaa cttataaagc tggtgcgcta tacgataatt gcctattgcc
     4321 cggaagcccg ggtaacagaa gataacttca ttgatgtttt gtgctgccgg atcaccgttg
     4381 taggcggctt cggcatcggt ggcaagcaga cagcgcattt ccggcagtgt ggaaatgaac
     4441 gcttcggaaa gtttttctgc ctggctgaag atcagctctt ccgcacagga agtacagctg
     4501 gtgtcggcca ggcaaaggcc cgcatagatt tgacggctga gcagctcgtg caacttttca
     4561 atattgaccc cggtatggaa acggatcgtc tgtgtactga tccgcgcatt cccgtaatag
     4621 ccaggaaaca ggattgcacg gcacaagtca atgatctcct ccagtacttc acctgaaggc
     4681 aatgcctctt catcgcggta ggcatgaaac agttgtttgt atgaacattc gtccgaaagc
     4741 ttttctactg tttcattcaa taccttgcta tgcttttgca atcccattat tttgaaagtc
     4801 ttattttggg caaaagtaca ttaaatatct gatatatgtg tacttttaat aggttataac
     4861 tgctttgaaa tgcgtttccg gcggccgttg atcagtaaag aagtcggaga atgtcacttt
     4921 gaagatgatg aaaccgtctt tggtgtattc ggctgcatag gtttccgtcc agatattatt
     4981 ctctttatct attcgattga cagggttggg taatgcagtt tgtgcttctt tgtcttcgcc
     5041 gtgatccaga tacatgtaac aggtaattaa gccttcttta taagcatcct gatatatgtc
     5101 gaaatcttta tcggcaattc tgtactcata catgtaaaaa ggttcgttat taccattgtc
     5161 gactaattcc cagtcgcttg acttaacttg tatatccttg tcaaatatcc agtaggttat
     5221 accgccatct tccccgtctc gtcccggagg gcccatcggt ccttcgcatg aagcgaacag
     5281 gaacaccatt aaaaatattg ctaacagatt tttcatatat tcactctctt aaatgtttag
     5341 tatttcttgt gcggtgcccc gaactctttg catgttactt catcgaggtc taccagccat
     5401 atttttacgt ttttcacagc cgggtcggaa taacggaatt ccttgtccga atactgtttc
     5461 ataattatat ccagcgcttc cgttttcttg tcgaagtctt cttcaaaccg cactttaccc
     5521 catgcgataa cgcttttgga acgcatacgg tagctgcaag ccacttcggg atgctggaat
     5581 accagatcat ggtcggtgct gaaggtgatg caaaccttcg ggttacgttc caggattgag
     5641 atacttcggc cttcctgcgc tgaatgtaaa tagataacac cgttccgata gccaaagttc
     5701 atgggtataa cgtaaggcgt accatccgta tcagccagtc cgacgaaaca gacatcgcaa
     5761 ctacggataa tctcctcgat atgttctttc tctgtgtgta ccagtgtctt cattactatt
     5821 tttaattatg cttttgcaaa catagtaaaa aagttcaact tctcggactt acttttgcga
     5881 ctttattata tatgtactgt tttcgtcaat gtgtcaaaat gtcaaatagt ccttctgtca
     5941 gtgagctgta cgtgtcctaa atcaggtttg ttgtttttat tcgctctacg ggatgattgc
     6001 gaatgtcttt attttaattg ttgattaata aatgtggctt tatgtttgat gatgtgtggt
     6061 agttgttgat aaatgtcgta aagtacattt gaaatatatg aatgtgctgt tcgggtttgg
     6121 tttggatatt tactcgttct ggagataaaa tgtgttgttt agcatgtgat ttgaggtccc
     6181 aaagcctgtt taaaataact tttctggaca gaattaacaa atttttcatc tgcaataaat
     6241 ctccatttca tttaaaatga aaaaaaaatc gttttaaacg agattacaat ttgtttaaaa
     6301 tgaagagtga aaatctatat gaatacgcta agtgttaaat attgtgtttt cggatcttct
     6361 atttctactg ttttgtgaaa tatagcagat acgtatatgc ggaaaaaata tacaaaatga
     6421 tctttaatcg ttgtaaattg tagcaaaatg gtattttctt gtctgttaaa aggattccgg
     6481 ataagaaaac actttttcaa gcgatttcct atatttgtaa ctccaattaa atataatacc
     6541 tgtatgaata aaactatcct gcttgttgtg ttttgctttt ccctgttcgt ttcggggtat
     6601 tcacagggaa tacgctttga ttcttaccct tctcatcccc ggttgctggt aaagaaagga
     6661 gaggagcaaa agattaaatc cgatctggct cttaatccgg agatgctccg gttgcataac
     6721 tatctacttg ggcaatgcga cgatctgatc acgacgcctg tgctggcata taaaaaagaa
     6781 gggaaacggt tgctggccgt atcgcgtgaa gccttgcggc gtatcttcta tctttcatat
     6841 gcttaccgga tgacaggaga ggataagtat cgtttgcggg cagagcagga gatgattgcc
     6901 gtgtgttcgt ttgccgattg gaacccgtct cattttctgg atacgggaga aatgactatg
     6961 gccgttgcaa tcggttatga ctggttgttc gatcggttat ctccggatgc ccggatgctg
     7021 gtgcaggagg cgattctgaa taaaggtttt gccccgtcga gggataaaag atataactgg
     7081 tttctgagag cgaccaataa ctggaaccag gtctgtaatg ccggactggt ttacggtgcg
     7141 ctggctgtgt tggaagatca tctggaagag gcccgtgaaa tcattgaacg tgctttgtct
     7201 acagtcggct tgactttgaa gggctatggt cccgatggcg cttatcccga aggatataat
     7261 tattggggat acgggactac cttccaggtt cttttgaatg cagcgttgga atccgccctg
     7321 gggactgacg gcggtctctc ttcggctgaa ggttttctgg cttctgcccg ttttatgcag
     7381 tttatgaccg gaacgaccgg taaatgcttt aacttcagcg attcccgtga gactgttttt
     7441 gctttgccgg ctatgtactg gtttgccgac aagctgcaag accctacact gctttggaat
     7501 gaaaaggata tgttgagtcg ggcggagttg tctttttcgg atgaggagag ccgtttcctt
     7561 ccgttgatac cgatttatgg ttcacaatat aaaatgaatg aactggtgcc tcctgccatg
     7621 aaattgtggg cggctaacgg acagacgcct gtcgtgctgg tccgtacggg atgggagaat
     7681 ggagaaggtt tctatctggg aataaaagga ggaacggctt cgaccagcca tgcccatatg
     7741 gatgccggat cgtttgtgtt cgatgctttg ggtgttcgct gggtgcagga cctggggatg
     7801 caggaatatt attcgctgga aaaggaaaat gtagatttat ggaatatgtc gcagaacggg
     7861 cagcgctgga atgtgttccg ttataataac ctggcgcata atacactgac tgtaaacggt
     7921 aaataccatg atgtaaaagg ttttgtacct gtgacaaata tctattcgga aacgcataaa
     7981 ctcggagctt ctctgaatat gacggacttg ttcggcggag aattggaaaa tgccgtccgt
     8041 gaagttgctc tgatcaatga aaaatatctg tcggtgattg atcgtgtaaa agctggcagt
     8101 cagccggcaa ctgtcagatg gacgattgta accggggcca ttccccgtgt attggacagt
     8161 catatggtgg aactgacaaa agacggcaaa tgtatgcaac tgatcgtcga tagtccatcc
     8221 gtaatttctg tgtccgtcct tgataatgta tcgaagaata gctatgatgc ttccaatgag
     8281 ggaacctgcc gtatcgtttt cgatgtaagt ctggaaagcg ggcaggagag cgatatcaaa
     8341 gtccggctgg ttcctgctgc tgactgataa ttaccagaac agcgccgtta cggttgcccc
     8401 tattgtaaaa tagtgtattt tgtgcttgct taaatggctc tcgccgtaga ctggttggct
     8461 gtctctgagg ctggttaaga tttcgtaagg tgctttcagg aacgtataat cgtaatctac
     8521 gaacatacgg atacccaggt tgcggctgac aattccggtc gctgaaatgc ctgtgcgtaa
     8581 aacatagttg ctgctaccgt tgcctttcat aaaagcaata ttatttatgg ttccgtatgg
     8641 gggggctttt cctgtaagtc catttccact tcatttttca ccagatagga atatccggcc
     8701 tggaactttg ttcctaaaag caatttactg gctacaggta acgagaaata aggccctgcc
     8761 gtaaaagtaa aaacaccggt cggatcggca tggacgcggg tgatgtcata tttggttgaa
     8821 ggggttgttc ctgtataaag cgacatgtcg aatgctatcg ggcttgccag cgctgttatt
     8881 tcgccgccga taccgaaata aggattgaag aagtaaccgc cttttacgct gacattggtt
     8941 gctcccggcg agctcaggcg tatattttta cctacctcga tacttccgtt gatgatactg
     9001 tatcctacgg cgaactccag gaaagaaggg cgccctcctt tgggggcaga ctccctgagc
     9061 ttgtcaggga gattcaagcc tttgtccttg aagatcaggt ctgccagaaa ataccctaac
     9121 tctgtggata agatgccgat accggccccg gccagtacgt cgctcagcca gtggcggttg
     9181 ttcagttgcc ggctgaaagc ggtggctgtg gcgactgtat atcccccgat actatataac
     9241 gggctgcggg tcagaccata ttcccggtgc atgatggtag cagccatgaa agcggttgcc
     9301 gtgtgtcccg aagggaatga gttgttcttt gagccgtcgg ggcgttcgcg tttgatcgta
     9361 tatttcatgc tgttgacggt agcggccatg atcgttgccg aaaaagcgtt cgatacgatc
     9421 atccggggcn nnnnnnnnnt ccacaccgcc gagcttcatc ccgtaaacag caagcaacgg
     9481 agtatattgc agaaaatcat cgtatctgta atggaagttg ggcgtatgcg tattgcgcaa
     9541 tgtccggaat ttatcaccct gcccatatgt tatggctgaa atggcgaaaa gaggaacagg
     9601 gacacgcagc atctggtata ccttattctc tgatattttg ttgtaagtgg tttcaaattc
     9661 atgttcttta tttatgaatc tcgtactatc tttccactga gcacaaacag acggtataaa
     9721 aatcatcata aataagaagc tcagcatttt acgttgtaac atacgatccc ctgattatgc
     9781 cacgaagata taaaaatgcc ggttagtact ggttacattt ttgttaattt atttattgaa
     9841 taggatttac cgtttgtccc tcctgaaatg tataggtttg attgacgaaa tatttcttta
     9901 atcgtttgcg tgatacgtgt atttagcata cctttgcctg ataattgagt atattgatat
     9961 gaatttctaa aaacaattaa ataacttaaa ttattatctt atgtggttac ttaattcttc
    10021 tatcgggaag aagctgataa tgagtgtatc aggccttttt cttgttttgt tcttattgtt
    10081 ccacttgtca atgaatgtgg cggctgcttt ctcgggagaa gcctataaca tgatttgttc
    10141 attgttggga gcaaattggt atgccgtggc agcaacattg gtgctggcag caggcgttgt
    10201 gattcacttt gtgtatgctg ttctccttac actgcaaaac cgtaaggctc gcggtaacga
    10261 ccgttatgca attaacgctc gtccgaaagg tgtggaatgg gcatctcaga acatgctggt
    10321 actgggtatt atcattatcc tgttcatggt gttgcacttc agccagttct ggtataagat
    10381 gatgttcgcc gaactcctag gcaatcacat ggtaacactt tgcgacggaa caacaaccgt
    10441 atctcctcag gacggtgcag cgtttatcaa ctactatttc cagggtaata tcctgaatac
    10501 agtgctgtat ctggtatggt acgtagcttt gtggttccac ctgactcacg ggttctggag
    10561 cgctattcag actatcggtt ggagtaacac gatctggatg aaccgttgga tctgcatttc
    10621 caagattgta gcaaccgtta tttgcgtagt gtttgctatc attactatcg ttttctacct
    10681 gaatggtgta ggtggtgact atgtagctgt ttgtgcagga cattaattta aggtgtaaca
    10741 atattgaaaa taaatcatta tgactcaaat agattctaaa atccctcagg gcccgttggc
    10801 tgagaagtgg aaaaattata aagatcatca gaaactggtg aaccccgcaa acaaacgtcg
    10861 tttggacgtg attgtagttg gtactggtct ggccggtgct tctgctgctg cctctctggc
    10921 agaaatggga ttcaacgtat tgaacttctg tatccaggat tctccccgtc gcgcacactc
    10981 aatcgccgca cagggtggta tcaatgctgc aaagaattat cagaatgatg gtgactctgt
    11041 ttaccgtctg ttctacgata caatcaaagg tggtgactat cgtgcccgcg aagcaaacgt
    11101 ttatcgtctg gctgaagttt ccaactctat tatcgaccag tgcgtagcac agggtgttcc
    11161 tttcgctcgc gaatacggtg gtctgctaga taaccgttca ttcggtggtg ctcaggtatc
    11221 ccgtacgttc tatgcccgcg gtcagaccgg acagcagttg ttgctgggtg cttactctgc
    11281 tttgagccgt atgatcggtt tgaacaaagt aaagatgtat acccgccacg aaatgctgga
    11341 cgttgtgaag gtggatggcc gtgcccgcgg tatcatcgca cgtaacctga tcacaggtca
    11401 gatcgaacgt ttttctgctc acgcagtagt ggtggcaaca ggtggttatg taaatacttt
    11461 cttcctgtct actaacgcaa tggcttccaa cggttctgct gcatggcagt gctacaagaa
    11521 aggtgcttac ttcgctaacc cttgtatggt gcagatccac ccgacttgtg taccggtgaa
    11581 aggtgactac cagtctaagc tgactttgat gtctgaatca ttgcgtaacg acggtcgtat
    11641 ctgggttccg aagaaactgg aagatgcaaa agcattacag gccggaacta agaaagggaa
    11701 agacattcct gaagcagacc gcgactacta tctggaacgc cgttatccgg cattcggtaa
    11761 cctggttccg cgtgacgtgg cttcacgtgc cgctaaagaa cgttgcgacg ccggcttcgg
    11821 tgtgaacaac acaggtctgg ccgtgttcct cgacttctcc gacgccatca accgtctggg
    11881 taaagatgtt gtaaaagcta aatatggtaa cttgttcgac atgtacgaag aaattaccaa
    11941 cgacgatcca tacgaaactc cgatgatgat ttatcctgca ttgcactact cgatgggtgg
    12001 tctgtgggtt gactatgaat tgatgacttc tattccgggt ctgttcgcta tcggtgaagc
    12061 taacttctct gaccacggag ctaaccgtct gggtgcttct gcgttgatgc agggattggc
    12121 cgatggctac tttgtattgc cttatacaat ccagaactat ctgtcagacc agatccaggt
    12181 tccgcgtttc agtaccgacc tgcctgagtt tgcagaagct gaaaagggga tcaaagaccg
    12241 catcaagaaa ttgatgagta tcaagggtaa agagtcggta gattctatcc ataagaaact
    12301 gggtcatatc atgtgggaac atgtaggtat ggcacgtgat gcaaaaggtt tgcaggaagc
    12361 gatccagatg ttgaaagagc tgaagaaaga gttctggagt aatgtatata ttccgggtga
    12421 agccgataac ctgaacgtag agttggataa ggcattgcgt ttggctgact ttattgagat
    12481 tggtacattg atggcacacg atgcattgga ccgtgccgaa tcttgtggag gacacttccg
    12541 tacagagcac cagaccgagg aaggcgaagc cctgcgtcat gacgataagt tcatgtacgt
    12601 atcttgttgg gaataccagg gtgaagacaa agatccggtt atgctgaagg aagatttgaa
    12661 ctatcagttc gttgttcctc aaacacgtaa ctacaagaag taataatcat caatcacaaa
    12721 aattagaatc atggataaag atataaaagt aacacttaaa gtttggcgtc agaaaagtcc
    12781 gaaagataaa ggacaatttg agacttacca aatagacaaa atcaatcaga gtgtttcttt
    12841 cctggaaatg ttagacattt tgaatgaacg tttggtcagt gaaggtaaag agccgatcgt
    12901 attcgatcac gactgtcgtg aaggtatctg cggtatgtgt tctttgtatg taaacggaca
    12961 tccgcacgga cctgcaaccg gcgcaactac ttgccagctt tatatgcgtc gcttcaatga
    13021 tggcgaaact attacaatcg aaccgtggcg ttctgccggt ttcccggtaa tccgcgactt
    13081 gatggtagac cgttatgctt acgataaaat tatccaggca ggtggtttcg tatcagtgaa
    13141 cacaggtggt gtacctgatg ccaattcaat cgctattcct cgtgcagatg ctgaaatggc
    13201 tatggatgct gctgcatgta tcggttgcgg tgcttgtgct gctgcttgta agaacggttc
    13261 ggctatgttg ttcgtttctg caaaggttag ccagttggct ctgttgcctc agggtaaggt
    13321 agaagctgct cgtcgtgcga aagcaatggt tgccaagatg gacgaactgg gcttcggtaa
    13381 ctgtaccaac acgcgtgctt gcgaaatgga atgtccgaag aacatctctg tcagcaacat
    13441 cgctcgtttg aaccgcgagt tcatttgtgc taaattgcaa gactaatata cattatatat
    13501 gtatgtccgg agaggcgttg cttatggcag cgcctcttct tttttgcccc tattttaaca
    13561 tttctgaagt catagataaa tatcttgaat gttgttagtg tttcttatat gctatacaac
    13621 actaattagc attttaacta ttgacaagtt ggagaatacc tgtatctttg tactgtggtt
    13681 ttttcataat agtattagat ttaaggttaa caaagttggt tagggcttgt cgtgagacag
    13741 gctttaattg tttatagggg tttgcgtccg gcatatccct ttttttagct ctccctgtat
    13801 tcctgcgggg tcattcctac atgttgccgg aaatatttgt tgaagaacga aaggttgtcg
    13861 aaacccaggg cgaatgcaat tttcttgacc ggcatatcgg tcgatttaag ctgcgctttg
    13921 gcatccataa tgatgatatt gctcaggata tccaatgcag tccgtccgct gacctttttt
    13981 atcacataac agaaatgctg caaggtgatg ttgagccttt tagcgtaata agacacgcta
    14041 tgctctttcg tgtagttttc catcgccagc tgtacgaact cccggcatat ttccatatta
    14101 cgcgtcatgg gagcattgct atatggcgta tgattcctgt ataattcaat aaccccttgc
    14161 atgaagatag taaagatagc cttgataatc tccttgttct cgatggtttt aggcatggaa
    14221 taagcattga tcagcaagtc gaaagcctgt tggtagagta aggatatatg ctccggcaaa
    14281 ggcatgatcg gactgtcgaa tatgacaggc agatagttcg taatcgtctt tatataattg
    14341 atatggctga cgaatacgga agaaaagcct gcaaaacaca gttttacatc atcggaaacc
    14401 tcatgtatct gaatgaagca acccgggggt aaggtgataa agtcgttctt ccggatggta
    14461 aactcagtta agtttacagt cgcgtggact gtcccttgta cgcaaagcac gaatatgcct
    14521 gccttgatct tgcacgggaa acgtccgtat tggttcagta tttcacctgt aatactgttt
    14581 cctacaataa aatctacggg gaggtcgaat ttaggaatat tgtcttccat acttttatat
    14641 acacttaatt gaatgtacaa agatagtttt tttgagacaa gttagtcgat aatcttaaat
    14701 atagaacatc gaatcccaca aatggagatt gttttgtgct gtataatagt tgaaatttgc
    14761 gaatgttttc aagtcttgct gatagatttg ttgggatggt atatatttgt ctatctgcta
    14821 aataagatat gggagctaat actaatagag aaatctaatc gataataaca atgagtacga
    14881 aaagaacaaa gagctctttc aggacaatga gcacaaacag aaaattagaa tctgttttcc
    14941 tgtttgtcac aggacggtgt aatgctaaat gtaaaatgtg tttctatgca aaagacatgg
    15001 ataaaaagga gaaagacctg acttttgaag aaatcaagac aatctccgaa acagccgggc
    15061 agttcaaccg tttgtgggta tccggcggtg aaccgacact gcgtgaggag ttacctgaaa
    15121 ttatagagat gttctacaag aataacgaga taaaggacgt gaatatccct accaacggat
    15181 tgaagcctga ccggatcgtc gcctgggtaa aacagatccg ccggaattgt ccggaactga
    15241 atatcaacct gagcctttct ttggacggtt tcggtgatac gcatgatata cagcgcggcg
    15301 ttcccggcaa tttctacaaa gcgatgggga cactgaagct gattgaaaaa aactttgctg
    15361 acgacggcag ggtgttgaaa aacctggcca ccgtaatcac caaatataac gagaatgagg
    15421 tcgaggatct gatgatatgg atgctgggac gtttccatct ttccaatcat attatcgaag
    15481 ctgcacgcgg catgacccgc gacgacggag tgaaggttct taccgagcct actttacgcg
    15541 ccttgcagga taaggttgtt cctatttata atgtatatgg ggagcgtatg gcggaggaaa
    15601 ccggtgggtt cagaaaacct atcgcccgtt tcttctacct gggtttcata cgtacattat
    15661 ataatgtacg tgcgaccaat atcgatcatc cgaccccctg gggtatggat tgtacggccg
    15721 gcgaaacaac actggtaata gactatgacg gtcgtttccg tgcctgtgaa cttcgcgaac
    15781 cgctcggtaa tgtaaaggat tatgattgca atatcgcaaa gattatggag agcgatgcca
    15841 tgaaacagga gattgccgct atcggtcatg gtgacaaggc taactgctgg tgtacgcatg
    15901 ggtgttggat cacttcatcg cttgttttca atccccgcaa gatgatcacg caggtctata
    15961 aaggataccg ggagatgaag aagctgaacc gtcctctgaa tatcagtgaa gagcttttgc
    16021 agagcatcga acgcaaatat gccttggacg aacagaaact ggtggagctg ggggttcgta
    16081 attaaaatag ttccgataac ggatcattta taaagccggt tgacgggaaa tatacctctg
    16141 ttaaccggct ttattgtgtt taagggaata attgtcaaat tatccggtag aattgccatt
    16201 tcccataggg gaaaaatgtc ggatctttgc atcataagtt aaactgataa acaaagaaag
    16261 acatgactac taaattaaaa gatttattcg acacatttct gaacattgca gcttcttcac
    16321 agaaactggg tattaacctg atccgcgtag ctatcctgat tatattcgta tggatcggcg
    16381 ggctgaaatt ctataattat gaagcggaag ggatcgttcc ttttgtggca aacagtccgt
    16441 ttatgagctt tttctatgca aagagtgcac cggaatacaa agaatataag ttgaaagaag
    16501 gtgaattcaa tgaagccaag catcagtggc atgtagaaaa caatacctat attttttcac
    16561 atggactagg cattatgatc atggcgatcg gtatcctgac tttcctgggt atcttttctc
    16621 cgaaaattgg cttgataggt tccggactgg cgatcataat gacattgggt acgctttcat
    16681 tcctggtgac aacacctgaa gtatgggtgc ccgatttggg aagcggagaa catggtttcc
    16741 ccttactgac cggagcaggt cggctggtaa taaaagatac ggcaatcata gccggagcga
    16801 tcgtggtatt gtccgactgt gcacaacgta tattaaagaa gaaataggaa caaaaagtgt
    16861 ttatttta
//
