LOCUS       c00085_gnlPro..        10568 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HELNOICE_85.
ACCESSION   c00085_gnlPro..
VERSION     c00085_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:57:14
            Original ID  :: gnl|Prokka|HELNOICE_85
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10568
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10568
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5513:9643]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5514..9643
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10568
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10568
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..205
                     /locus_tag="ctg85_1"
                     /transl_table=11
                     /translation="GDWTHIYKDSIIGDPVLSIDELTQVVKESNKRKNLPMINVRIYQD
                     GTISPKSYALLKELNNRISKGE"
     CDS             1247..2455
                     /locus_tag="ctg85_2"
                     /transl_table=11
                     /translation="MEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIYHYSEILNVD
                     ELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEWDILSSNEGI
                     FWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSLPWSDYLLEY
                     YENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQKYKYNWIWGY
                     SSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLIDKYLCKLHW
                     EECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREEDFRNNNGGII
                     NDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVLEKEKMKFLL
                     ELV"
     CDS             2977..3573
                     /locus_tag="ctg85_3"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             3649..5196
                     /locus_tag="ctg85_4"
                     /transl_table=11
                     /translation="MAALYPIGIQNFEKIRKEGYLYVDKTALIYQMVKTGSYYFLSRPR
                     RFGKSLLVSTLEAYFQGKEELFEGLAMEKLEQDWLEYPILHLDLNAERYSEASSLDSIL
                     QRHLNLWEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELL
                     QDEYRSILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICG
                     MTETEIHAYMEQGVLDLTRNLQMDYEEVCMELKRRYDGYHFTHRSQGMYNPFSLLNTFA
                     KSDFGDYWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSG
                     YLTIKSYNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDV
                     DAFLSRLQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTD
                     HYIYIMEFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             5514..7349
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             7376..9076
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             9089..9643
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_7"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-18, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             9680..10411
                     /locus_tag="ctg85_8"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             10453..10566
                     /locus_tag="ctg85_9"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVIGY"
ORIGIN
        1 gggtgactgg acgcacattt ataaagattc cattatcggt gatcctgttc tttccattga
       61 cgaattgacg caggtagtga aagaatctaa caaacgaaaa aatcttccga tgattaatgt
      121 ccggatttat caggatggaa cgatttctcc gaaatcgtat gctttgttga aagaactgaa
      181 caatcgtatc agtaaaggag aatgaccgga aattatcgaa tatgaagcga atggaggctc
      241 agaaataaga attcaattga ttgggtgatg tgtcaaaata gtaattactg aacgctaacg
      301 actcagaaca cgcagacagg cacaaacttt tattaaaaaa taattattgt ctgcgctccg
      361 tctgcgttcg gtaatagtgt tttgacacac cttctcgttt ttaggggaaa aaatcaatct
      421 cccaatggag ttttataaat ttgatttcat ctttcagtgt ttgtaacata ttataggaca
      481 gttgtttgct gtgaagggag ataaaatatt gttcgaacaa aagcgtacgt cttttcccaa
      541 gaatacgtac gattttcccc tatagtccgg cagattatac cctgtaaagt agcgtccggt
      601 accctatacc ctattggtat gtacgttata gggtaggtgt accgtcatac cggtactgct
      661 atcccatccg gccggcatcg tagtgtcagc actactcaca tgactgtgtg aagacgagtg
      721 gttcttcccc aacggataac tatccgtgtc cacatagata actatctatt tccccacaga
      781 tgcctactca tcggaagggt tcctgttacg gttccaaaaa caatagtgaa aaggctggtt
      841 tcaccacaaa aggatataat acagtgtgtt acgagtgtga aggcagaggt atgaaaacca
      901 tggaggggga agattgtttc cgtcgcggac tttctcattg attttaaact accatttcaa
      961 ttatgtaaaa cggtgttttg tgttggcaaa aatggcactt atcaaaaaaa gaacatttcc
     1021 ccatccgttt tctttcgggc gagaactgtt ttggtgcggt tgccctgtat tttcgctttc
     1081 tttcttgcaa gttcaagatt ttcttgataa cttaccactg tgtttcttct aaatccgtac
     1141 aatacataat tatttgaaac ttagtaatta aaaataatta ttttagcaga aagaggaaac
     1201 actttattta tttcaaactg tgaaatttaa acaggctcta attattatgg aaaagttgga
     1261 tgatatgaaa ttaactgtat tatatattga atatagaaat ttttttattg atgtattaag
     1321 tagattttat ggttttgaaa aatatgatat atatcattat agtgaaattt tgaatgttga
     1381 tgaattgtgt agaaatgaag ctttaaattg ggatatgtat ctgatagaat tttggggtaa
     1441 agaaaaaatt aattgggaat atttgagtgg aaataagtgt ttgtcatgga cagcagatct
     1501 ttttgataaa tattatgatt attgggaatg ggatatcttg tcttctaatg agggaatatt
     1561 ctggaatgag ttgctgctta ataagtataa atctaagtta aattggaatt tgttgagctt
     1621 aaataaatcg ttaccgtggt caattgattt tataaatcgc tatgttgata gattaaattg
     1681 ggttaattta agtgctaatc tgtcattgcc ttggtctgac tatttgttgg aatattatga
     1741 gaatttatgg gattggaact tgataagtgc caatccatcg ttgccttgga ctgatgattt
     1801 aatcattaaa tatatggatc gtttaaattg ggctggatta agtatgaatc cagcgttacc
     1861 ttggagttct gagtttatac aaaagtataa atataactgg atctggggat attcatcaga
     1921 ttgggtaatg accgatgata taggtttatg tggcaattcg ggtattcact ggaatgagga
     1981 attgatagag atgtttgatg gttttattga ttggggagag cttagtttaa atacaggaga
     2041 tatgtggaat gaatgtttga ttgataaata tttatgtaaa ttgcattggg aagaatgctg
     2101 gtgtcctcct ttgggtatgg gaggtctcag tagtaatcct tcattgcctt ggagcttgga
     2161 ctttgtggat aaatataaac cttatttaaa tataaaagaa atttgttcta atatgtcttt
     2221 cccttggcgt gaagaggatt ttagaaataa taatggtgga ataataaatg attgtgataa
     2281 atcttactgg aaattattga gtatgaatga aggtttacct tggtctgtag gagtactata
     2341 tgataataga tgttggtttg attggaatct aatgaaagga aatgtgaaag tatacgataa
     2401 ctgtttaagt gttttagaaa aagaaaagat gaaattttta cttgaattag tttgattgaa
     2461 gtatcaaaaa atggtcgtgg atgattgggt aggatagtta tataagtgac gaagctgaag
     2521 aaaagaatat gcgcctatat tttatagaaa agtctattgc tatgctaata caagtaaaga
     2581 tcgtgtgttg aaaaatatga catcgtattt tggggacagt gaaaatatta ttagttaata
     2641 cagtctgcaa aatttatatt actctgatag gttggagcaa tcgttctttg cagggatgat
     2701 atgttttatc cggtaatgat tggtgaagac ggaagctttc ctgtcaaatg aaatatgaca
     2761 tgcttatggc tttggatatg tctggaaata atacctttgc tatatgcctt ttacaaaaat
     2821 attcctaaga agaaatagat tgttttatta ggattgttat tttgttggtg acaatccttt
     2881 ataataaaag agcaagtctg tgaaaaaaag taattcaaag taagaagaaa atcatacaat
     2941 taaccattat ttctgctcat ttctgtcata aacatagtgg ttgtagtttg taacgtgttg
     3001 gtggcaggtt gtgcctcagg taaggtattt gacagggtgg aaaagatacc acatcgtaaa
     3061 gtcggtttgt tgttggggac tgctccggtt actccttggg gaacgaaaaa tctttatttt
     3121 acgtatcgta ttgatgcggc agtcaaattg tttcatgcaa aaaaggttga ttactttatt
     3181 gtaagtggtg ataatcattc aacagattat gatgagccga cttgtatgcg tgattcgtta
     3241 gttgcctgtg gtgtaccgga tgagcgaatt atttcggatt atgtcggttt tcgaacgctt
     3301 gatttggaag tgcgatgtaa agccattttt ggacaggata gcgttactgt tatttcgcag
     3361 tcttttcata acgagcgtgc gatctatttg gcgggtcata atcaaataga tgcgattgca
     3421 ttcaatgccc aagatgtgac ttctgtgtgg acaacctggt tgaggggaca tagtcgtgag
     3481 cttttggctc gggttaaaat atttatagac ttgattattg gtaagcaacc ccgtttttgg
     3541 ggggagaagg tcaagattcc ggaaatccga tgaaaatgta atataataag atacttattg
     3601 ataaaaaata agttaccttt gtcttgatag ataatataaa aacggtttat ggctgcactt
     3661 tatcctattg gcatacaaaa tttcgagaag attcgtaagg aggggtatct ctatgttgat
     3721 aaaacagcgt tgatttatca aatggtgaag accgggagtt attacttcct gagtcgtccg
     3781 cgccgtttcg gcaaatcgtt gttggtttcg actttggagg cctattttca gggtaaggag
     3841 gagttgttcg agggattggc gatggagaag ctggaacagg attggttgga gtatccgata
     3901 ttgcatttgg atttaaatgc ggagaggtat tcggaggctt cgtccttgga tagtattttg
     3961 caacgtcatt tgaacctgtg ggaagataca tggggaaaag atgaacggga aaagactttg
     4021 tccgatcgtt ttataggggt gatccgccgg gcaaaagctc gatcgggaag gcgtgtggtc
     4081 attttggtgg atgaatacga caaacctttg ttgcaggcta ttggggatga gctgttgcag
     4141 gatgaatacc gttctatatt aaaaccgttt tatggggtgt tgaagacgat ggacggtgat
     4201 atccgttttg ctttgctgac aggtgtgaca aagttcggta aagtaagtgt gttcagtgat
     4261 ttgaacaatt tgatggatat ttcgatggat gatcgttatg ttgagatttg tggtatgacc
     4321 gagacggaaa tccatgcgta tatggaacaa ggggtgttgg atttgactcg taatctgcaa
     4381 atggattatg aagaagtttg catggaattg aaacgccgtt atgatggtta tcattttact
     4441 cataggtcgc aaggcatgta caatccgttc agtttgttaa acacatttgc gaagtctgac
     4501 tttggagatt actggtttga gacaggtacc ccctcttact tggtcgagct gttgaagcat
     4561 accgactatg acttgtacaa tatggcacat acggaaacga atgcagatgt gttgaacagt
     4621 atcgatgccg tttcgcgtaa cccgataccg gttatttacc aaagtggtta tttgacgatc
     4681 aaatcctata atcctagatt taaaatatat acattgggct ttccaaatca ggaagtagaa
     4741 gaggggtttc tgaattattt gcttccatat tacacttctg tcaatgttat tgatacttcc
     4801 ttccagcttt ttaaattcat taaagaaatc gagtctgggg atgtggatgc tttccttagc
     4861 cggttgcaaa gtttttttgc cgatacgcca tatgaattga ttcgaaatct ggaagtgcac
     4921 taccagaacg tcctgttcat cgtcttcaaa ctggtcggtt tctatgtgaa ggtggaatat
     4981 cgtacttccc gtggtcgcat tgacctggtg ttgcaaaccg atcattacat ttatataatg
     5041 gagtttaagt tggatggcac gacagaggag gcgatgaggc agatcgaaga gaagcagtat
     5101 gccttgcctt ttgcctcgga tgaacggaaa ctttttaaga taggggtgaa ctttgataat
     5161 gaaacacgga acatagccgg ttggtcggtc gattgatgta gattttaata atactgttaa
     5221 aatgcaagat gaaccgccct cttttattga taaatgaaag aaaaagtaag atttttcttt
     5281 taaatccttt gctcgtacaa attattattc tacatttgca gcgtcaaaca aaataaagac
     5341 gataagaaaa gatgatgaac aatgtattac atattattct cgtggtggtc cttctagtca
     5401 ttagtaggta aggagaaagg tgtgtaagaa gttgtgaagt cgtaaaagat atttcttaag
     5461 cctttctcca tatagagaag ggctttttta ttgactaaaa gataaaaaca gatatgatga
     5521 agaatccgtt aagaagctcc tatagcacag aaggcagacg tatggccgga gcccgtgcat
     5581 tatggcgtgc caacggcatg aaagaagaac agttcggtaa accgatcatt gccattgtga
     5641 attcatttac ccagtttgta ccgggccatg tgcatctaca cgagatcgga cagcaggtaa
     5701 aagcggaaat cgaaaagctc ggttgctttg ccgcagaatt taatacgatc gctattgatg
     5761 acggtattgc tatgggacac gacggaatgc tttattctct gccttcccgc gacatcattg
     5821 ctgacagtgt ggaatatatg gtgaatgcgc ataaggctga tgcaatggtt tgtatcagta
     5881 actgcgacaa gattactccg ggtatgctga tggccagtat gcgtctgaat attccgacaa
     5941 tctttgtatc cggcggtccg atggaagccg gtaatctgga cggacgtgca ctcgatttga
     6001 tcgacgccat gattgaagcg gctgacgatt ctatcagcga tgaacaagta gaaaaggtgg
     6061 aacgttccgc ttgcccgacc tgcggttgct gttctggtat gttcacggct aactctatga
     6121 actgtctgaa cgaagcgatt ggattggctc ttcccggcaa cggaacagtt gttgcaacac
     6181 atgccaaccg tacccgcctg ttcaaaaaag ccgcgaagat gattgttgat aatgccttta
     6241 aatattatcg tgacggcgat gattccgtat tgcctcgcag tattgccacc cgtcaggcct
     6301 ttctgaatgc tatgtcgctg gatattgcca tggggggatc gacgaataca gtccttcacc
     6361 tgttggccgt ggctcatgaa gcggaagtcg attttacaat gaaagacatc gatatgcttt
     6421 cacgcaaaac accggttatc tgtaaagtgg ctccgagttg ttcttatcat gtggaagatg
     6481 tgaaccgtgc cggaggtatt atcggtatta tgaatgagct ggtaaaagcc ggtctggtgg
     6541 acggttccgt gaaacgtgcg gatggtctga ctttgaatga ggctatcgac caatactgca
     6601 ttacctctgt aaatgtaacg gaagaagcaa tcaatattta taaaagtgct ccggcccacc
     6661 gtttcaatct ggtgctcgga tcgcaggaaa gttattataa agaactggat accgaccgtg
     6721 caaccggatg tatccgcgat gtggaacatg cttatgtgaa agacggcggt ctggctgttc
     6781 tgtatggaaa tattgcacag gacggttgtg tggttaaaac agccggggta gatgaaagta
     6841 tcttccgttt tgccggccct gccaaagtat tcgattcgca ggatgccgct tgcgaaggta
     6901 tcctgaaaga tcaagtcgtc tccggcgatg tcgtcgttat cacctatgaa ggtcctaagg
     6961 gtggtccggg tatgcaggaa atgttgtatc ctacctctta tataaagagt aaacatctgg
     7021 gtaaagaatg tgcgttaatc acagacggac gcttcagcgg tggaacatcg ggtttgtcaa
     7081 tcggacatat ttctcccgaa gcggctgcag gcggagcgat tggcttagtg aaagacggcg
     7141 atattatcga aattaatatt cccgaaagaa ccatacatgt aaaggtgaca gacgaagaac
     7201 tggccaaacg ccgtgaagcg gaagaagccc gcggaacaaa agcctttaca cctcctttcc
     7261 gccaacgtac ggtatcgaaa gcactgaaag catatgcaaa gatggttgct tcggccgata
     7321 agggcggtgt acgaatagta gaagattaat aaacaccaaa tactatattt tagagatgga
     7381 caaacaaaag ataaccggtt cggaagcttt gctgaaagcg ctgatcgctg aaggagtaga
     7441 tactatcttc ggttatccgg gtgggcaggc gataccaatt tacgatagtt tatacgatta
     7501 cagagatcag ttaaaacata ttctggtgcg ccacgaacaa ggtgcaacac atgctgcaca
     7561 gggatatgcc cgtgtttccg gaaaagtggg agtaacggtg gttacttcgg gtcccggggc
     7621 aaccaatacc atcactggta ttgccgatgc gctgatggac agtacaccga tggtggtgat
     7681 tgccggccag gttccgtctc cgctgcttgg aacagatgct ttccaggaag ttgatgtgat
     7741 cggtatcaca caaccgatta ccaaatgggc ttaccagata cgccgcccgg aagaaattgc
     7801 ttgggccgtt tcccgtgctt tctatatcgc atcgaccggt cgcccgggac ctgtggtact
     7861 ggatttggcg aaagatgcac aggtgggttt ggtagattat gagtatcaga aagtggatta
     7921 tgttcgtagt taccaacctg aaccggatat cagggaggaa cgtatcgagg cggctgcttc
     7981 attgataaat aatgccaaaa agccattctg tctggtaggg cagggggtta tcctgggagg
     8041 agctgaagaa gaactgaaag aattcttgtt gaaaaacgat ataccagccg gttctaccgt
     8101 attgggcttg tctgcattac cttcggactt cccattaaat aaaggtatgt tggggatgca
     8161 tggaaatgtc ggaccgaacc gcaagacaaa cgaatgtgac gtgctgattg ctatcggtat
     8221 gcgtttcgat gatcgcgtaa ccggcgacct gaagacttat gccaagcagg caaagattat
     8281 ccacctggat atcgacaatt cggagatcgg aaagaatgtg ccggtcgacg tgaaagtgct
     8341 gggaaatgcc aagcatacga ttccgatgat tacggcttta ctggaagaac ggaagcgtcc
     8401 ggaatggaat gctgaattcg aaccggatga aaaagaggaa tataataagg taatagaaaa
     8461 agaactctat cctaccgaag gccaactgaa aatgggcgaa gtagtccgta aggtttccga
     8521 agcaaccgat aatgatgcga ttctggttac ggatgtaggt cagaaccaga tgatgggtgt
     8581 tcgctatttc aaatataaac aaacacgcag cgtagttact tcaggaggtt tgggaacgat
     8641 gggctttggc cttcccgccg ccattggagc gaagctggga gcgcctgacc gtacggtctg
     8701 tttctttacc ggcgacggtg gtatccagat gactatccag gagttgggaa ctatcatgca
     8761 ggaaaatctg aatgtaaaga tcatcgttct taacaacaat ttcctgggaa tggtacgcca
     8821 gtggcaggag ctgttcttca acgaacggta ttcgaatacc atcatgaaga atccggattt
     8881 tgtagcgata gccaaggctt ttggtattgc ttcccgtgcg gtagataaac gggaagactt
     8941 ggatgaggcg attgctgaaa tgttgaatca cgatggtgcc tatatgttgg ttgccaatgt
     9001 ggaaacttgt ggtatggtat atccgatggt tccggccgga ggaagcgtga caaacatgat
     9061 tttgggtgat aagtaaggag gagaaactat gaatacaaaa caattatata ccgttattat
     9121 cttttcggaa aacactgttg gtcttctgaa tcagataact gttatcttta cgcgccggca
     9181 actgaacatt gagacgcttt ctgtttctcc ctctgctata aagggaatac ataagtttac
     9241 aattactacc tttgccgacg aggatacgat cgacaaggtc gtaaaacaga tcgacaagcg
     9301 tgtggatatc ctgaaagcct attataatac ggatgaagac ctggtttacc aggaaatcgc
     9361 tctttataaa ctgagtaccg aactctttat caagatgggg acggttgagg atctgatccg
     9421 taagtacaat gcccgtatcc ttgaaatgaa tgaggattgt gtggtgttgg aaaagagtgg
     9481 tcattatgat gagacacagg ctttgtttaa agaattgagt gagacgatcg gtgtcctgca
     9541 atttatccgt tccggacgcg ttgctataac gaagagtaag gtagaacgtc tgagcgacat
     9601 gttatctgca atggaaaaga agttgcagga aaaacatgtc tgagaataat aaggaaacat
     9661 tttgtaaata aagtaaatta tggagaagaa caaagtagga gaatttcatt tcgtaacaga
     9721 gtcttatctg acggacttcc ggggacgtat tacaatccct atgatcggaa cttatttgtt
     9781 gcatgctgct tcttgccatg ccgccgaccg tggattcgga tataacgata tgaccgaaag
     9841 gcataccgcc tgggttcttt cccgtctggc tatcgagatg acttcttatc ctgccatgtc
     9901 tgaatccgta actttatata cctgggtgga tgaggtcggt aagttgttta ccagccgttg
     9961 ctttgaactg gtgaacggcg aaggcaagac ctttggcttt gcccgctcta tctgggcggc
    10021 tatcgatatg gaaacccgcc gcccgacctt gctcgatgtg gagggcctga gtgcttatat
    10081 caccgaccgt ccctgtccga ttgaaaaacc gggtaaaatt gctccggtgg aaaacaacac
    10141 ttccggcgaa ccttaccgtg tgaagtatag tgacctggac gtaaacggcc acctgaacag
    10201 tatcaaatac atggaacacc tgctcgactt gttcgatatc agtctgttcc gagaaaaaga
    10261 gataagccgt ttcgaaatag cttatcagtc cgaaggaaag tatgggatgg agctgactct
    10321 ccataaccag gaagtatccc tcgataaata taatatggca atctgtaacg acggcaaagc
    10381 catcagccgc gctgccgtta cctggatctg aaaaacaaat tattttatat acattttaat
    10441 agtaaaaaga aaatggcagt aatgaatttt ggcggcgttg acgaaaacgt agtaacccgc
    10501 gaagaatttc cgttggaaaa ggcaagagaa gtattgaaag acgaaacaat cgctgtaata
    10561 ggttacgg
//
