## Fri Jul 12 14:02:56 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_948626605.1/GCA_948626605.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_948626605.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_948626605.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NEGHOLOK_00011	349741.Amuc_1378	9.06e-44	164.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_5,Phage_integrase
NEGHOLOK_00021	349741.Amuc_1432	2.58e-69	212.0	COG3015@1|root,COG3015@2|Bacteria	2|Bacteria	MP	regulation of cell-substrate adhesion	-	-	-	-	-	-	-	-	-	-	-	-	NlpE
NEGHOLOK_00024	497964.CfE428DRAFT_5806	2.03e-38	153.0	COG4383@1|root,COG4383@2|Bacteria	2|Bacteria	L	Mu-like prophage protein gp29	-	-	-	-	-	-	-	-	-	-	-	-	DUF935,Phage_Mu_F
NEGHOLOK_00025	349741.Amuc_1360	5.05e-130	369.0	COG3926@1|root,COG3926@2|Bacteria	2|Bacteria	S	Glycosyl hydrolase 108	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3,Peptidase_M15_4
NEGHOLOK_00032	1300143.CCAV010000006_gene4317	1.49e-08	58.5	2D0K9@1|root,32T8S@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00036	349741.Amuc_1377	1.99e-138	411.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,2ITGD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DnaB-like helicase C terminal domain	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NEGHOLOK_00044	497964.CfE428DRAFT_1294	4.61e-55	188.0	28HHC@1|root,2Z7T2@2|Bacteria,46VSN@74201|Verrucomicrobia	74201|Verrucomicrobia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_24
NEGHOLOK_00048	349741.Amuc_1794	9.41e-72	229.0	COG1974@1|root,COG1974@2|Bacteria,46XX7@74201|Verrucomicrobia,2IVZZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NEGHOLOK_00055	794903.OPIT5_01350	2.58e-28	120.0	COG0582@1|root,COG0582@2|Bacteria,46W0S@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NEGHOLOK_00057	349741.Amuc_0263	3.35e-116	332.0	COG0319@1|root,COG0319@2|Bacteria,46WBN@74201|Verrucomicrobia,2IUS4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
NEGHOLOK_00058	349741.Amuc_0264	0.0	1139.0	COG1480@1|root,COG1480@2|Bacteria,46S4P@74201|Verrucomicrobia,2ITIA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	7TM receptor with intracellular HD hydrolase	-	-	-	ko:K07037	-	-	-	-	ko00000	-	-	-	7TM-7TMR_HD,HD
NEGHOLOK_00059	349741.Amuc_0265	1.22e-246	677.0	COG0416@1|root,COG0416@2|Bacteria,46S8C@74201|Verrucomicrobia,2ITU1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NEGHOLOK_00060	349741.Amuc_0266	2.73e-38	127.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NEGHOLOK_00061	349741.Amuc_0267	4.98e-117	334.0	COG1399@1|root,COG1399@2|Bacteria,46TBP@74201|Verrucomicrobia,2IURG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NEGHOLOK_00062	349741.Amuc_0268	6.98e-80	236.0	COG0537@1|root,COG0537@2|Bacteria,46SZ4@74201|Verrucomicrobia,2IUKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NEGHOLOK_00063	349741.Amuc_0269	3.6e-243	669.0	COG0009@1|root,COG0009@2|Bacteria,46SUC@74201|Verrucomicrobia,2ITRQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	-	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NEGHOLOK_00064	349741.Amuc_0270	3.81e-129	367.0	COG0703@1|root,COG0703@2|Bacteria,46T2U@74201|Verrucomicrobia,2IUGN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NEGHOLOK_00065	349741.Amuc_0271	9.56e-51	160.0	COG0228@1|root,COG0228@2|Bacteria,46WC2@74201|Verrucomicrobia,2IUP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S16	-	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NEGHOLOK_00068	349741.Amuc_0273	1.6e-215	595.0	COG4974@1|root,COG4974@2|Bacteria,46SQ4@74201|Verrucomicrobia,2ITUM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NEGHOLOK_00069	349741.Amuc_0274	6.23e-184	513.0	COG5126@1|root,COG5126@2|Bacteria,46XN6@74201|Verrucomicrobia,2IW8M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DTZ	EF-hand, calcium binding motif	-	-	-	-	-	-	-	-	-	-	-	-	EF-hand_5
NEGHOLOK_00070	349741.Amuc_0275	1.62e-65	200.0	COG1862@1|root,COG1862@2|Bacteria,46T88@74201|Verrucomicrobia,2IUY8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Preprotein translocase subunit	-	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NEGHOLOK_00071	349741.Amuc_0276	5.68e-282	769.0	COG0343@1|root,COG0343@2|Bacteria,46TZR@74201|Verrucomicrobia,2ITG4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
NEGHOLOK_00072	349741.Amuc_0277	2.45e-150	421.0	COG0220@1|root,COG0220@2|Bacteria,46T5A@74201|Verrucomicrobia,2IUBK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Putative methyltransferase	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NEGHOLOK_00073	349741.Amuc_0278	4.32e-174	485.0	COG1051@1|root,COG4111@1|root,COG1051@2|Bacteria,COG4111@2|Bacteria,46SHC@74201|Verrucomicrobia,2IU63@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NEGHOLOK_00074	349741.Amuc_0279	2.43e-126	358.0	COG0797@1|root,COG0797@2|Bacteria,46WZB@74201|Verrucomicrobia,2IVVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
NEGHOLOK_00075	349741.Amuc_0280	1.91e-204	566.0	COG1039@1|root,COG1039@2|Bacteria,46V1X@74201|Verrucomicrobia,2ITVX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ribonuclease HII	-	-	3.1.26.4	ko:K03471	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NEGHOLOK_00076	349741.Amuc_0281	1.9e-62	191.0	COG0776@1|root,COG0776@2|Bacteria,46T4V@74201|Verrucomicrobia,2IUR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	bacterial (prokaryotic) histone like domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_DNA_binding
NEGHOLOK_00082	349741.Amuc_0287	1.43e-142	403.0	COG0811@1|root,COG0811@2|Bacteria,46SUA@74201|Verrucomicrobia,2IUER@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
NEGHOLOK_00083	349741.Amuc_0288	3.02e-170	475.0	COG0382@1|root,COG0382@2|Bacteria	2|Bacteria	H	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate	-	-	2.5.1.39	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R05000,R05615	RC00209,RC02895	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
NEGHOLOK_00084	349741.Amuc_0289	2.73e-263	723.0	COG0760@1|root,COG0760@2|Bacteria,46SU4@74201|Verrucomicrobia,2IUC6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	SurA N-terminal domain	-	-	5.2.1.8	ko:K03771	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NEGHOLOK_00085	349741.Amuc_0290	0.0	2054.0	COG3250@1|root,COG3250@2|Bacteria,46U9M@74201|Verrucomicrobia,2IV89@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NEGHOLOK_00086	349741.Amuc_0291	0.0	1810.0	COG0525@1|root,COG0525@2|Bacteria,46SGP@74201|Verrucomicrobia,2IU1F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NEGHOLOK_00087	349741.Amuc_0292	3.74e-204	564.0	2AW3R@1|root,31MYP@2|Bacteria,46X7Q@74201|Verrucomicrobia,2IUWD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4332
NEGHOLOK_00088	349741.Amuc_0293	6.79e-79	234.0	COG0093@1|root,COG0093@2|Bacteria,46VID@74201|Verrucomicrobia,2IUB7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NEGHOLOK_00089	349741.Amuc_0294	2.19e-56	175.0	COG0186@1|root,COG0186@2|Bacteria,46T6M@74201|Verrucomicrobia,2IUPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NEGHOLOK_00090	349741.Amuc_0295	5.78e-35	119.0	COG0255@1|root,COG0255@2|Bacteria,46TAV@74201|Verrucomicrobia,2IUWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L29 protein	-	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NEGHOLOK_00091	349741.Amuc_0296	3.42e-97	282.0	COG0197@1|root,COG0197@2|Bacteria,46ST6@74201|Verrucomicrobia,2IUCE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	-	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NEGHOLOK_00092	349741.Amuc_0297	4.27e-155	436.0	COG0092@1|root,COG0092@2|Bacteria,46SN9@74201|Verrucomicrobia,2ITPJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NEGHOLOK_00093	349741.Amuc_0298	4.97e-70	211.0	COG0091@1|root,COG0091@2|Bacteria,46T5F@74201|Verrucomicrobia,2IUMZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome	-	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NEGHOLOK_00094	349741.Amuc_0299	4.05e-152	429.0	2FI21@1|root,349UX@2|Bacteria,46W3I@74201|Verrucomicrobia,2IUIJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00095	349741.Amuc_0300	1.05e-58	181.0	COG0185@1|root,COG0185@2|Bacteria,46T4G@74201|Verrucomicrobia,2IUPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NEGHOLOK_00096	349741.Amuc_0301	1.85e-203	562.0	COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,2ITK3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NEGHOLOK_00097	349741.Amuc_0302	8.72e-58	179.0	COG0089@1|root,COG0089@2|Bacteria,46WBX@74201|Verrucomicrobia,2IUPY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
NEGHOLOK_00098	349741.Amuc_0303	9.43e-132	375.0	COG0088@1|root,COG0088@2|Bacteria,46SWJ@74201|Verrucomicrobia,2IU4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L4/L1 family	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NEGHOLOK_00099	349741.Amuc_0304	3.86e-149	419.0	COG0087@1|root,COG0087@2|Bacteria,46SQV@74201|Verrucomicrobia,2IU4D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NEGHOLOK_00100	349741.Amuc_0305	3.67e-65	198.0	COG0051@1|root,COG0051@2|Bacteria,46SVV@74201|Verrucomicrobia,2IUCB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S10p/S20e	-	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NEGHOLOK_00101	349741.Amuc_0306	0.0	1404.0	COG0480@1|root,COG0480@2|Bacteria,46SFV@74201|Verrucomicrobia,2ITYS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	-	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NEGHOLOK_00102	349741.Amuc_0307	2.91e-104	301.0	COG0049@1|root,COG0049@2|Bacteria,46V3W@74201|Verrucomicrobia,2IU3Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S7p/S5e	-	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NEGHOLOK_00103	349741.Amuc_0308	4.16e-85	251.0	COG0048@1|root,COG0048@2|Bacteria,46SQR@74201|Verrucomicrobia,2IU8K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S12/S23	-	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NEGHOLOK_00104	349741.Amuc_0309	0.0	1038.0	COG0696@1|root,COG0696@2|Bacteria,46U4C@74201|Verrucomicrobia,2ITXW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	BPG-independent PGAM N-terminus (iPGM_N)	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,iPGM_N
NEGHOLOK_00105	349741.Amuc_0310	3.37e-97	282.0	COG0824@1|root,COG0824@2|Bacteria,46VXK@74201|Verrucomicrobia,2IUVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
NEGHOLOK_00106	349741.Amuc_0311	1.82e-274	752.0	COG3852@1|root,COG3852@2|Bacteria,46Z4V@74201|Verrucomicrobia,2ITPC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS
NEGHOLOK_00107	349741.Amuc_0312	0.0	880.0	COG2204@1|root,COG2204@2|Bacteria,46SFE@74201|Verrucomicrobia,2ITIG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Bacterial regulatory protein, Fis family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_8,Response_reg,Sigma54_activat
NEGHOLOK_00108	349741.Amuc_0313	0.0	1231.0	COG1928@1|root,COG1928@2|Bacteria,46UW1@74201|Verrucomicrobia,2IU5E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal four TMM region of protein-O-mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00109	349741.Amuc_0314	3.08e-52	164.0	COG1722@1|root,COG1722@2|Bacteria	2|Bacteria	L	exodeoxyribonuclease VII activity	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NEGHOLOK_00110	349741.Amuc_0315	0.0	1248.0	COG1154@1|root,COG1154@2|Bacteria,46SAU@74201|Verrucomicrobia,2ITIS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	HI	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NEGHOLOK_00111	349741.Amuc_0316	3.99e-183	509.0	COG0457@1|root,COG0457@2|Bacteria,46X6U@74201|Verrucomicrobia,2IUS6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00112	349741.Amuc_0317	2.31e-127	362.0	COG1381@1|root,COG1381@2|Bacteria,46VUW@74201|Verrucomicrobia,2IUNX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Recombination protein O N terminal	-	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NEGHOLOK_00113	349741.Amuc_0318	9.67e-251	689.0	COG0795@1|root,COG0795@2|Bacteria,46STR@74201|Verrucomicrobia,2IUBP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K07091	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
NEGHOLOK_00114	349741.Amuc_0319	0.0	905.0	COG1160@1|root,COG1160@2|Bacteria,46SJY@74201|Verrucomicrobia,2ITU6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NEGHOLOK_00115	349741.Amuc_0320	1.24e-230	635.0	COG0444@1|root,COG0444@2|Bacteria,46U0J@74201|Verrucomicrobia,2ITGK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NEGHOLOK_00117	349741.Amuc_0333	1.78e-154	433.0	COG4845@1|root,COG4845@2|Bacteria	2|Bacteria	V	Chloramphenicol acetyltransferase	cat	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
NEGHOLOK_00119	349741.Amuc_0334	0.0	1821.0	COG0577@1|root,COG0577@2|Bacteria,46XDE@74201|Verrucomicrobia,2IVIV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NEGHOLOK_00120	349741.Amuc_0335	2.88e-167	468.0	COG1136@1|root,COG1136@2|Bacteria,46X0J@74201|Verrucomicrobia,2IVS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NEGHOLOK_00121	349741.Amuc_0336	0.0	1474.0	COG4774@1|root,COG4774@2|Bacteria,46Z6G@74201|Verrucomicrobia,2IWPQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
NEGHOLOK_00122	349741.Amuc_0337	1.46e-204	566.0	COG0287@1|root,COG0287@2|Bacteria,46SSN@74201|Verrucomicrobia,2IU8S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
NEGHOLOK_00124	349741.Amuc_0339	0.0	1776.0	COG0204@1|root,COG0477@1|root,COG0204@2|Bacteria,COG2814@2|Bacteria,46VGN@74201|Verrucomicrobia,2ITZY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGIP	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
NEGHOLOK_00125	349741.Amuc_0340	3.42e-111	319.0	COG2131@1|root,COG2131@2|Bacteria,46WJA@74201|Verrucomicrobia,2IUDA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Cytidine and deoxycytidylate deaminase zinc-binding region	-	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NEGHOLOK_00127	349741.Amuc_0342	1.86e-94	275.0	COG1765@1|root,COG1765@2|Bacteria,46T1Y@74201|Verrucomicrobia,2IUE7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
NEGHOLOK_00128	349741.Amuc_0343	0.0	1547.0	COG4232@1|root,COG4233@1|root,COG4232@2|Bacteria,COG4233@2|Bacteria,46S6T@74201|Verrucomicrobia,2ITNE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Disulphide bond corrector protein DsbC	-	-	-	-	-	-	-	-	-	-	-	-	DsbC,Thioredoxin_7
NEGHOLOK_00129	349741.Amuc_0344	3.99e-176	490.0	COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_00130	349741.Amuc_0345	2.75e-142	401.0	COG0847@1|root,COG0847@2|Bacteria,46X72@74201|Verrucomicrobia,2IUEP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Exonuclease	-	-	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
NEGHOLOK_00131	349741.Amuc_0346	0.0	1608.0	COG0249@1|root,COG0249@2|Bacteria,46SCK@74201|Verrucomicrobia,2ITUY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NEGHOLOK_00132	349741.Amuc_0347	4.69e-79	234.0	COG0799@1|root,COG0799@2|Bacteria,46T8H@74201|Verrucomicrobia,2IUTW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NEGHOLOK_00133	349741.Amuc_0348	0.0	1563.0	COG0465@1|root,COG0465@2|Bacteria,46SB7@74201|Verrucomicrobia,2ITNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,Peptidase_M41
NEGHOLOK_00135	349741.Amuc_0350	2.13e-256	703.0	COG1106@1|root,COG1106@2|Bacteria	2|Bacteria	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NEGHOLOK_00136	349741.Amuc_0351	1.25e-199	552.0	COG0447@1|root,COG0447@2|Bacteria,46Z3Z@74201|Verrucomicrobia,2ITPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Enoyl-CoA hydratase/isomerase	menB	-	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
NEGHOLOK_00139	349741.Amuc_0354	7.55e-302	824.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	1.B.17,2.A.6.2	-	-	OEP
NEGHOLOK_00143	349741.Amuc_0358	9.85e-147	413.0	COG1136@1|root,COG1136@2|Bacteria,46XHT@74201|Verrucomicrobia,2IVYF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NEGHOLOK_00146	349741.Amuc_0361	0.0	2321.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,46TJ4@74201|Verrucomicrobia,2ITSH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
NEGHOLOK_00147	349741.Amuc_0362	8.38e-98	284.0	2ERYI@1|root,33JHP@2|Bacteria,46WPE@74201|Verrucomicrobia,2IUEZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00148	349741.Amuc_0363	9e-192	533.0	COG0300@1|root,COG0300@2|Bacteria,46V6A@74201|Verrucomicrobia,2IUAY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NEGHOLOK_00149	349741.Amuc_0364	0.0	956.0	2EYYY@1|root,33S5Q@2|Bacteria,46UHA@74201|Verrucomicrobia,2ITNH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Fungal chitosanase of glycosyl hydrolase group 75	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_75
NEGHOLOK_00150	349741.Amuc_0365	9.68e-221	608.0	COG1562@1|root,COG1562@2|Bacteria,46VIE@74201|Verrucomicrobia,2IUH8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Squalene/phytoene synthase	-	-	2.5.1.21	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	-	R00702,R02872,R06223	RC00362,RC00796,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	SQS_PSY
NEGHOLOK_00151	349741.Amuc_0366	0.0	991.0	COG3604@1|root,COG3604@2|Bacteria,46YU4@74201|Verrucomicrobia,2IVAR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Bacterial regulatory protein, Fis family	-	-	-	ko:K02584	ko02020,map02020	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_8,Sigma54_activat
NEGHOLOK_00152	349741.Amuc_0367	0.0	1141.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia,2IU71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
NEGHOLOK_00154	349741.Amuc_0369	0.0	1330.0	COG3525@1|root,COG3525@2|Bacteria,46ZK1@74201|Verrucomicrobia,2IVDU@203494|Verrucomicrobiae	2|Bacteria	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_00156	349741.Amuc_0371	0.0	1768.0	COG3292@1|root,COG3292@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Baseplate_J,CHB_HEX_C_1,Cu_amine_oxidN1,F5_F8_type_C,His_kinase,Reg_prop,Reprolysin_5,Sortilin-Vps10,VCBS,Y_Y_Y
NEGHOLOK_00157	349741.Amuc_0372	0.0	968.0	COG0076@1|root,COG0076@2|Bacteria,46TV2@74201|Verrucomicrobia	74201|Verrucomicrobia	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
NEGHOLOK_00159	349741.Amuc_0373	5.21e-142	399.0	COG1670@1|root,COG1670@2|Bacteria,46X7U@74201|Verrucomicrobia,2IUXM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NEGHOLOK_00160	349741.Amuc_0374	0.0	2347.0	COG0587@1|root,COG0587@2|Bacteria,46SG0@74201|Verrucomicrobia,2ITPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase alpha chain like domain	-	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NEGHOLOK_00161	349741.Amuc_0375	1.22e-237	654.0	COG0167@1|root,COG0167@2|Bacteria,46S5W@74201|Verrucomicrobia,2IU2W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Dihydroorotate dehydrogenase	pyrD	-	1.3.5.2	ko:K00254	ko00240,ko01100,map00240,map01100	M00051	R01868	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NEGHOLOK_00162	349741.Amuc_0376	4.34e-152	427.0	COG0352@1|root,COG0352@2|Bacteria,46T6K@74201|Verrucomicrobia,2IUF9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiamine monophosphate synthase	-	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NEGHOLOK_00163	349741.Amuc_0377	1.1e-159	447.0	COG1309@1|root,COG1309@2|Bacteria,46X7B@74201|Verrucomicrobia,2IUUJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NEGHOLOK_00164	349741.Amuc_0378	2.31e-164	459.0	COG0526@1|root,COG0526@2|Bacteria,46X0G@74201|Verrucomicrobia,2IWD9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_8
NEGHOLOK_00165	349741.Amuc_0379	0.0	1568.0	COG0457@1|root,COG1413@1|root,COG0457@2|Bacteria,COG1413@2|Bacteria,46UPB@74201|Verrucomicrobia,2IV7Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c554 and c-prime	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C554,Paired_CXXCH_1
NEGHOLOK_00166	349741.Amuc_0380	1.88e-308	842.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	74201|Verrucomicrobia	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF21
NEGHOLOK_00167	349741.Amuc_0381	2.59e-312	852.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	2|Bacteria	S	PFAM CBS domain containing protein	tlyC	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NEGHOLOK_00168	349741.Amuc_0382	0.0	1351.0	COG1185@1|root,COG1185@2|Bacteria,46SBP@74201|Verrucomicrobia,2ITWE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NEGHOLOK_00169	349741.Amuc_0383	3.01e-49	157.0	COG0184@1|root,COG0184@2|Bacteria,46T87@74201|Verrucomicrobia,2IUVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal_S15	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NEGHOLOK_00170	349741.Amuc_0384	8.11e-152	426.0	COG0110@1|root,COG0110@2|Bacteria,46TEB@74201|Verrucomicrobia,2IUHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Mac
NEGHOLOK_00171	349741.Amuc_0385	1.94e-212	586.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	ko:K19234,ko:K19236	ko01503,map01503	-	-	-	ko00000,ko00001,ko01002,ko01011	-	-	-	YkuD
NEGHOLOK_00172	349741.Amuc_0386	0.0	1118.0	COG4626@1|root,COG4626@2|Bacteria,46ZJ1@74201|Verrucomicrobia,2IV51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00175	349741.Amuc_0389	2.16e-200	553.0	COG0101@1|root,COG0101@2|Bacteria,46SSV@74201|Verrucomicrobia,2IU7R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	-	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NEGHOLOK_00176	349741.Amuc_0390	1.04e-144	407.0	COG1057@1|root,COG1057@2|Bacteria,46YSF@74201|Verrucomicrobia,2IUSZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NEGHOLOK_00177	349741.Amuc_0391	4.02e-167	466.0	COG0739@1|root,COG0739@2|Bacteria,46VAI@74201|Verrucomicrobia,2IU93@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NEGHOLOK_00178	349741.Amuc_0392	0.0	1465.0	COG3669@1|root,COG3669@2|Bacteria,46TW6@74201|Verrucomicrobia	74201|Verrucomicrobia	G	PFAM coagulation factor 5 8 type domain protein	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
NEGHOLOK_00180	349741.Amuc_0394	1.33e-174	487.0	COG4968@1|root,COG4968@2|Bacteria,46X8E@74201|Verrucomicrobia,2IUZZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prepilin-type N-terminal cleavage methylation domain	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_00182	349741.Amuc_0395	9.93e-180	501.0	COG0689@1|root,COG0689@2|Bacteria,46U55@74201|Verrucomicrobia,2ITNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
NEGHOLOK_00183	349741.Amuc_0396	0.0	946.0	COG1524@1|root,COG1524@2|Bacteria,46UZ5@74201|Verrucomicrobia,2ITHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
NEGHOLOK_00184	349741.Amuc_0397	0.0	1516.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_00185	349741.Amuc_0398	6.94e-153	429.0	COG0132@1|root,COG0132@2|Bacteria,46VJB@74201|Verrucomicrobia,2IUDQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	AAA domain	-	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
NEGHOLOK_00187	349741.Amuc_0400	4.86e-201	557.0	COG1624@1|root,COG1624@2|Bacteria,46SSQ@74201|Verrucomicrobia,2IU56@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DisA bacterial checkpoint controller nucleotide-binding	-	-	-	-	-	-	-	-	-	-	-	-	DisA_N
NEGHOLOK_00188	349741.Amuc_0401	2.97e-142	401.0	2ESTV@1|root,33KCA@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00189	349741.Amuc_0403	6.38e-151	424.0	COG1136@1|root,COG1136@2|Bacteria,46UQZ@74201|Verrucomicrobia,2IU5Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NEGHOLOK_00190	349741.Amuc_0404	8.39e-197	546.0	COG0414@1|root,COG0414@2|Bacteria,46SRN@74201|Verrucomicrobia,2ITKC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
NEGHOLOK_00191	349741.Amuc_0405	1.48e-120	347.0	COG2825@1|root,COG2825@2|Bacteria,46T22@74201|Verrucomicrobia,2IUS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Outer membrane protein (OmpH-like)	-	-	-	ko:K06142	-	-	-	-	ko00000	-	-	-	OmpH
NEGHOLOK_00192	349741.Amuc_0406	2.31e-187	527.0	COG1044@1|root,COG1044@2|Bacteria,46SAD@74201|Verrucomicrobia,2ITQF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	lpxD	-	2.3.1.191	ko:K02536	ko00540,ko01100,map00540,map01100	M00060	R04550	RC00039,RC00166	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hexapep,LpxD
NEGHOLOK_00193	349741.Amuc_0407	8.12e-195	539.0	COG0600@1|root,COG0600@2|Bacteria,46TJF@74201|Verrucomicrobia,2IU1M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NEGHOLOK_00194	349741.Amuc_0408	1.63e-189	526.0	COG1116@1|root,COG1116@2|Bacteria,46TJD@74201|Verrucomicrobia,2ITUG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NEGHOLOK_00195	349741.Amuc_0409	3.92e-247	679.0	COG0715@1|root,COG0715@2|Bacteria,46WUQ@74201|Verrucomicrobia,2IV5U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1_2
NEGHOLOK_00197	349741.Amuc_0052	8.93e-223	665.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	hyl	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	2.3.1.48,3.2.1.169,3.2.1.35	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	M00076,M00077	R07824,R07825,R09672,R09673,R10905	RC00059,RC00397,RC00451,RC00746	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH84	-	F5_F8_type_C,Glyco_hydro_20b,NAGidase
NEGHOLOK_00198	349741.Amuc_0413	6.23e-118	337.0	COG0241@1|root,COG0241@2|Bacteria,46T3Q@74201|Verrucomicrobia,2IW66@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Polynucleotide kinase 3 phosphatase	-	-	3.1.3.82,3.1.3.83	ko:K03273	ko00540,ko01100,map00540,map01100	M00064	R05647,R09771	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	HAD_2,Hydrolase_like
NEGHOLOK_00199	349741.Amuc_0414	8.25e-131	371.0	COG0279@1|root,COG0279@2|Bacteria,46SXU@74201|Verrucomicrobia,2IUZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
NEGHOLOK_00200	349741.Amuc_0415	0.0	971.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,46T1J@74201|Verrucomicrobia,2IVXQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	pfkB family carbohydrate kinase	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	PfkB
NEGHOLOK_00201	349741.Amuc_0416	1.06e-44	145.0	COG0828@1|root,COG0828@2|Bacteria,46WP6@74201|Verrucomicrobia,2IWJ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S21	-	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NEGHOLOK_00202	349741.Amuc_0417	3.01e-311	847.0	COG0001@1|root,COG0001@2|Bacteria,46S67@74201|Verrucomicrobia,2ITGJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NEGHOLOK_00203	349741.Amuc_0418	1.39e-258	708.0	COG0666@1|root,COG0666@2|Bacteria,46XNF@74201|Verrucomicrobia,2IW95@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ankyrin repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00204	349741.Amuc_0419	0.0	1246.0	COG0477@1|root,COG2814@2|Bacteria,46TKN@74201|Verrucomicrobia,2IU9N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	Sugar_tr
NEGHOLOK_00205	349741.Amuc_0420	0.0	982.0	2A4XA@1|root,30TJ4@2|Bacteria,46X7N@74201|Verrucomicrobia,2IUVT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00206	349741.Amuc_0421	0.0	1148.0	COG0008@1|root,COG0008@2|Bacteria,46S4X@74201|Verrucomicrobia,2ITW6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (E and Q), anti-codon binding domain	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NEGHOLOK_00207	349741.Amuc_0422	9.59e-288	786.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,46S5K@74201|Verrucomicrobia,2ITV0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	GTP cyclohydrolase II	-	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
NEGHOLOK_00208	349741.Amuc_0423	1.48e-104	303.0	COG0054@1|root,COG0054@2|Bacteria,46T5S@74201|Verrucomicrobia,2IUDV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
NEGHOLOK_00209	349741.Amuc_0424	4.7e-205	568.0	COG0781@1|root,COG0781@2|Bacteria,46T7V@74201|Verrucomicrobia,2IUM8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NEGHOLOK_00210	349741.Amuc_0425	1.1e-197	548.0	COG0552@1|root,COG0552@2|Bacteria,46SKC@74201|Verrucomicrobia,2ITIZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	SRP54-type protein, GTPase domain	-	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NEGHOLOK_00211	349741.Amuc_0426	1.07e-261	716.0	COG0820@1|root,COG0820@2|Bacteria,46SBD@74201|Verrucomicrobia,2ITGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Elongator protein 3, MiaB family, Radical SAM	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
NEGHOLOK_00212	349741.Amuc_0427	0.0	925.0	COG0305@1|root,COG0305@2|Bacteria,46SKM@74201|Verrucomicrobia,2ITGD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DnaB-like helicase C terminal domain	-	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NEGHOLOK_00213	349741.Amuc_0428	3.76e-181	506.0	COG3210@1|root,COG3210@2|Bacteria	2|Bacteria	U	domain, Protein	-	-	-	ko:K20276	ko02024,map02024	-	-	-	ko00000,ko00001	-	-	-	DUF4347,Haemagg_act,PATR
NEGHOLOK_00214	349741.Amuc_0429	6.87e-153	430.0	COG2020@1|root,COG2020@2|Bacteria	2|Bacteria	O	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	ICMT,PEMT
NEGHOLOK_00215	349741.Amuc_0430	6.9e-288	788.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,46SRG@74201|Verrucomicrobia,2ITHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Competence-damaged protein	-	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NEGHOLOK_00216	349741.Amuc_0431	0.0	911.0	COG0469@1|root,COG0469@2|Bacteria,46SBJ@74201|Verrucomicrobia,2ITNV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
NEGHOLOK_00217	349741.Amuc_0432	1.07e-124	354.0	COG0454@1|root,COG0456@2|Bacteria,46WVW@74201|Verrucomicrobia	74201|Verrucomicrobia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NEGHOLOK_00221	349741.Amuc_0436	1.99e-191	530.0	COG0560@1|root,COG0560@2|Bacteria,46XDN@74201|Verrucomicrobia,2IUJ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
NEGHOLOK_00222	349741.Amuc_0437	4.36e-142	401.0	COG0522@1|root,COG0522@2|Bacteria,46SNI@74201|Verrucomicrobia,2ITP0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S4/S9 N-terminal domain	-	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NEGHOLOK_00223	349741.Amuc_0438	2.11e-121	347.0	COG0100@1|root,COG0100@2|Bacteria,46STW@74201|Verrucomicrobia,2IU6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NEGHOLOK_00224	349741.Amuc_0439	1.11e-79	237.0	COG0099@1|root,COG0099@2|Bacteria,46VYP@74201|Verrucomicrobia,2IUGG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NEGHOLOK_00225	349741.Amuc_0440	3.9e-270	737.0	COG1600@1|root,COG1600@2|Bacteria,46SDV@74201|Verrucomicrobia,2ITS7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Domain of unknown function (DUF1730)	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF1730,Fer4_16
NEGHOLOK_00226	349741.Amuc_0441	1.96e-223	617.0	COG3660@1|root,COG3660@2|Bacteria,46VHN@74201|Verrucomicrobia,2IVP2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mitochondrial fission ELM1	-	-	-	ko:K07276	-	-	-	-	ko00000	-	-	-	Mito_fiss_Elm1
NEGHOLOK_00227	349741.Amuc_0442	2.1e-269	737.0	COG0438@1|root,COG0438@2|Bacteria,46U78@74201|Verrucomicrobia,2IVJU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NEGHOLOK_00228	349741.Amuc_0443	3.24e-271	742.0	COG0758@1|root,COG0758@2|Bacteria,46SGR@74201|Verrucomicrobia,2ITVU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	LU	DNA recombination-mediator protein A	-	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A,HHH_5
NEGHOLOK_00229	349741.Amuc_0444	4.25e-219	604.0	COG1686@1|root,COG1686@2|Bacteria,46SZY@74201|Verrucomicrobia,2IU54@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NEGHOLOK_00230	349741.Amuc_0445	5.5e-262	718.0	COG0012@1|root,COG0012@2|Bacteria,46S8D@74201|Verrucomicrobia,2ITV8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NEGHOLOK_00231	349741.Amuc_0446	4.93e-268	733.0	COG0404@1|root,COG0404@2|Bacteria,46UPA@74201|Verrucomicrobia,2ITVC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminomethyltransferase folate-binding domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
NEGHOLOK_00232	349741.Amuc_0447	6.67e-86	253.0	COG0509@1|root,COG0509@2|Bacteria,46VKU@74201|Verrucomicrobia,2IUJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	-	GCV_H
NEGHOLOK_00233	349741.Amuc_0448	0.0	1895.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,46S4N@74201|Verrucomicrobia,2ITRK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
NEGHOLOK_00235	349741.Amuc_0450	6.98e-156	436.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
NEGHOLOK_00236	349741.Amuc_0451	0.0	1458.0	COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae	2|Bacteria	P	PA14 domain	-	-	-	ko:K01138	-	-	-	-	ko00000,ko01000	-	-	-	PA14,Sulfatase
NEGHOLOK_00237	349741.Amuc_0452	0.0	1134.0	COG0513@1|root,COG0513@2|Bacteria,46U0S@74201|Verrucomicrobia,2ITPY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DbpA RNA binding domain	-	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
NEGHOLOK_00238	349741.Amuc_0453	6.16e-176	491.0	2CH0A@1|root,2ZANK@2|Bacteria,46V2X@74201|Verrucomicrobia,2IUG4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00239	349741.Amuc_0454	0.0	1051.0	COG2755@1|root,COG2755@2|Bacteria,46X92@74201|Verrucomicrobia,2IV2A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	3.1.1.53	ko:K05970	-	-	-	-	ko00000,ko01000	-	-	-	SASA
NEGHOLOK_00240	349741.Amuc_0455	1.41e-242	665.0	COG2755@1|root,COG2755@2|Bacteria,46XGP@74201|Verrucomicrobia,2IVVB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00241	349741.Amuc_0456	1.84e-105	304.0	COG2259@1|root,COG2259@2|Bacteria,46VKN@74201|Verrucomicrobia,2IUYQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
NEGHOLOK_00242	349741.Amuc_0457	4.07e-246	675.0	COG0150@1|root,COG0150@2|Bacteria,46SJ4@74201|Verrucomicrobia,2ITTU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AIR synthase related protein, N-terminal domain	-	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NEGHOLOK_00243	349741.Amuc_0458	0.0	1300.0	COG0034@1|root,COG0034@2|Bacteria,46UKZ@74201|Verrucomicrobia,2ITSB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	-	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	-
NEGHOLOK_00244	349741.Amuc_0459	1.26e-139	394.0	COG1595@1|root,COG1595@2|Bacteria,46SWN@74201|Verrucomicrobia,2IUE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NEGHOLOK_00246	349741.Amuc_0461	2.34e-208	576.0	COG0265@1|root,COG0265@2|Bacteria,46XRR@74201|Verrucomicrobia,2IWFN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00247	349741.Amuc_0462	1.31e-81	241.0	COG2026@1|root,COG2026@2|Bacteria,46T5H@74201|Verrucomicrobia,2IUPU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	DJ	Addiction module toxin, RelE StbE family	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
NEGHOLOK_00248	349741.Amuc_0463	8.37e-126	358.0	COG0452@1|root,COG0452@2|Bacteria,46SPU@74201|Verrucomicrobia,2IUB8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavoprotein	-	-	4.1.1.36	ko:K01598	ko00770,ko01100,map00770,map01100	M00120	R03269	RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
NEGHOLOK_00250	349741.Amuc_0465	2.31e-259	709.0	COG0739@1|root,COG0739@2|Bacteria,46V20@74201|Verrucomicrobia,2IU1Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NEGHOLOK_00251	349741.Amuc_0466	0.0	1654.0	COG1729@1|root,COG1729@2|Bacteria,46T9I@74201|Verrucomicrobia,2IUIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16
NEGHOLOK_00252	349741.Amuc_0467	0.0	903.0	COG0494@1|root,COG2326@1|root,COG0494@2|Bacteria,COG2326@2|Bacteria,46UPR@74201|Verrucomicrobia,2IUNN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
NEGHOLOK_00253	349741.Amuc_0468	2.48e-173	484.0	COG1349@1|root,COG1349@2|Bacteria,46T4S@74201|Verrucomicrobia,2IUQ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NEGHOLOK_00254	349741.Amuc_0469	1.94e-104	301.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
NEGHOLOK_00255	349741.Amuc_0470	9.7e-279	763.0	COG1104@1|root,COG1104@2|Bacteria,46TMY@74201|Verrucomicrobia,2ITTD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NEGHOLOK_00256	349741.Amuc_0471	8.3e-158	442.0	COG0452@1|root,COG0452@2|Bacteria,46WUX@74201|Verrucomicrobia,2IU6G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	DNA / pantothenate metabolism flavoprotein	-	-	6.3.2.5	ko:K21977	ko00770,map00770	M00120	R04231	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP
NEGHOLOK_00257	349741.Amuc_0472	1.67e-272	745.0	COG1162@1|root,COG1162@2|Bacteria,46UNB@74201|Verrucomicrobia,2ITJY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase
NEGHOLOK_00258	349741.Amuc_0473	5.45e-232	638.0	29SKQ@1|root,30DS1@2|Bacteria,46XQW@74201|Verrucomicrobia,2IWE1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Aspartyl protease	-	-	-	-	-	-	-	-	-	-	-	-	Asp_protease_2
NEGHOLOK_00259	349741.Amuc_0474	4.79e-309	842.0	COG1519@1|root,COG1519@2|Bacteria,46SK9@74201|Verrucomicrobia,2ITS4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)	-	-	2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15	ko:K02527	ko00540,ko01100,map00540,map01100	M00060,M00080	R04658,R05074,R09763	RC00009,RC00077,RC00247	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT30	-	Glycos_transf_N
NEGHOLOK_00260	349741.Amuc_0475	2.75e-130	370.0	COG0742@1|root,COG0742@2|Bacteria,46T62@74201|Verrucomicrobia,2IUEM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Conserved hypothetical protein 95	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth95
NEGHOLOK_00261	349741.Amuc_0476	2.84e-211	584.0	2C40J@1|root,33272@2|Bacteria,46X77@74201|Verrucomicrobia,2IUU6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00263	349741.Amuc_0478	4.28e-224	617.0	COG2326@1|root,COG2326@2|Bacteria,46SAH@74201|Verrucomicrobia,2ITM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
NEGHOLOK_00264	349741.Amuc_0479	0.0	1004.0	2FFXY@1|root,347UV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00265	349741.Amuc_0480	0.0	1540.0	COG5434@1|root,COG5434@2|Bacteria,46W9Z@74201|Verrucomicrobia,2IV74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,NPCBM
NEGHOLOK_00267	349741.Amuc_0482	6.18e-199	550.0	COG1073@1|root,COG1073@2|Bacteria,46WVD@74201|Verrucomicrobia,2IURZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	alpha beta	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Abhydrolase_6
NEGHOLOK_00268	349741.Amuc_0483	6.74e-106	305.0	COG0802@1|root,COG0802@2|Bacteria,46T3C@74201|Verrucomicrobia,2IUJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NEGHOLOK_00269	349741.Amuc_0484	1.93e-66	202.0	COG0261@1|root,COG0261@2|Bacteria,46T6P@74201|Verrucomicrobia,2IUNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal prokaryotic L21 protein	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NEGHOLOK_00270	349741.Amuc_0485	2.14e-57	177.0	COG0211@1|root,COG0211@2|Bacteria,46T48@74201|Verrucomicrobia,2IUMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L27 protein	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NEGHOLOK_00271	349741.Amuc_0486	6.78e-100	290.0	COG0735@1|root,COG0735@2|Bacteria,46W8N@74201|Verrucomicrobia,2IUJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferric uptake regulator family	-	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NEGHOLOK_00272	349741.Amuc_0487	1.24e-179	500.0	COG0396@1|root,COG0396@2|Bacteria,46SGE@74201|Verrucomicrobia,2ITY7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATPases associated with a variety of cellular activities	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
NEGHOLOK_00273	349741.Amuc_0488	0.0	960.0	COG0719@1|root,COG0719@2|Bacteria,46SGN@74201|Verrucomicrobia,2IU30@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
NEGHOLOK_00274	349741.Amuc_0489	9.06e-297	810.0	COG0719@1|root,COG0719@2|Bacteria,46S8S@74201|Verrucomicrobia,2ITRN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09015	-	-	-	-	ko00000	-	-	-	UPF0051
NEGHOLOK_00275	349741.Amuc_0490	0.0	1453.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NEGHOLOK_00276	349741.Amuc_0491	0.0	1047.0	COG3119@1|root,COG3119@2|Bacteria,46U02@74201|Verrucomicrobia,2ITYT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NEGHOLOK_00277	349741.Amuc_0492	2.93e-233	641.0	COG0502@1|root,COG0502@2|Bacteria,46S63@74201|Verrucomicrobia,2ITKQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin and Thiamin Synthesis associated domain	-	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NEGHOLOK_00278	349741.Amuc_0493	0.0	920.0	COG0161@1|root,COG0161@2|Bacteria,46SBR@74201|Verrucomicrobia,2ITS3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Aminotransferase class-III	-	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NEGHOLOK_00279	349741.Amuc_0494	3.63e-135	382.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
NEGHOLOK_00282	349741.Amuc_0497	3.2e-76	227.0	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	EamA,Multi_Drug_Res,TPT
NEGHOLOK_00283	349741.Amuc_0498	1.08e-73	221.0	COG2076@1|root,COG2076@2|Bacteria	2|Bacteria	P	Multidrug Resistance protein	-	-	-	ko:K03297,ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	EamA,Multi_Drug_Res
NEGHOLOK_00284	349741.Amuc_0499	6.54e-221	609.0	COG0463@1|root,COG0463@2|Bacteria,46TW8@74201|Verrucomicrobia,2IW1Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_00285	349741.Amuc_0500	2.98e-115	330.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	flmH	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_3
NEGHOLOK_00286	349741.Amuc_0501	2.94e-285	778.0	COG0399@1|root,COG0399@2|Bacteria,46SEI@74201|Verrucomicrobia,2ITTP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NEGHOLOK_00287	349741.Amuc_0502	2.58e-276	754.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia,2IUUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00288	349741.Amuc_0503	7.66e-124	352.0	COG3091@1|root,COG3091@2|Bacteria	2|Bacteria	K	SprT-like family	sprT	-	-	-	-	-	-	-	-	-	-	-	SprT-like
NEGHOLOK_00289	349741.Amuc_0504	1.38e-139	393.0	2FADU@1|root,342N6@2|Bacteria,46VMD@74201|Verrucomicrobia,2IUDF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00290	349741.Amuc_0505	1.24e-90	266.0	COG0355@1|root,COG0355@2|Bacteria,46T0F@74201|Verrucomicrobia,2IUNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NEGHOLOK_00291	349741.Amuc_0506	0.0	914.0	COG0055@1|root,COG0055@2|Bacteria,46SCC@74201|Verrucomicrobia,2IU0R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NEGHOLOK_00292	349741.Amuc_0507	4.5e-201	557.0	COG0224@1|root,COG0224@2|Bacteria,46SGU@74201|Verrucomicrobia,2ITXP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NEGHOLOK_00293	349741.Amuc_0508	0.0	978.0	COG0056@1|root,COG0056@2|Bacteria,46SB5@74201|Verrucomicrobia,2ITR0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
NEGHOLOK_00294	349741.Amuc_0509	6.46e-86	253.0	COG0712@1|root,COG0712@2|Bacteria,46TC4@74201|Verrucomicrobia,2IUUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase delta (OSCP) subunit	-	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NEGHOLOK_00295	349741.Amuc_0510	4.38e-78	237.0	COG0711@1|root,COG0711@2|Bacteria,46SYI@74201|Verrucomicrobia,2IUEN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase B/B' CF(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NEGHOLOK_00296	452637.Oter_0880	1.65e-11	60.8	2BFTV@1|root,329NU@2|Bacteria,46Z0C@74201|Verrucomicrobia,3K8FB@414999|Opitutae	414999|Opitutae	S	PFAM H transporting two-sector ATPase C subunit	-	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
NEGHOLOK_00297	349741.Amuc_0512	6.27e-219	604.0	COG0356@1|root,COG0356@2|Bacteria,46SVZ@74201|Verrucomicrobia,2IU94@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	ATP synthase A chain	-	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NEGHOLOK_00298	349741.Amuc_0513	0.0	1413.0	2A0ZF@1|root,30P4Q@2|Bacteria,46X87@74201|Verrucomicrobia,2IUZ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00299	349741.Amuc_0514	0.0	1613.0	COG0768@1|root,COG0768@2|Bacteria,46TSQ@74201|Verrucomicrobia,2ITKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NEGHOLOK_00300	349741.Amuc_0515	5.1e-153	429.0	COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_00301	349741.Amuc_0516	3.11e-271	741.0	COG4299@1|root,COG4299@2|Bacteria,46S60@74201|Verrucomicrobia,2IUUP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00302	349741.Amuc_0517	0.0	1383.0	COG3345@1|root,COG3345@2|Bacteria,46TWB@74201|Verrucomicrobia	74201|Verrucomicrobia	G	Raffinose synthase or seed imbibition protein Sip1	-	-	-	-	-	-	-	-	-	-	-	-	Raffinose_syn
NEGHOLOK_00304	349741.Amuc_0519	4.09e-218	600.0	COG0657@1|root,COG0657@2|Bacteria,46ZJ8@74201|Verrucomicrobia,2IUH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NEGHOLOK_00305	349741.Amuc_0520	8.29e-223	614.0	2B13X@1|root,31THQ@2|Bacteria,46X3Y@74201|Verrucomicrobia,2IUFM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00306	349741.Amuc_0521	7.33e-110	317.0	COG3247@1|root,COG3247@2|Bacteria	2|Bacteria	U	response to pH	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
NEGHOLOK_00307	349741.Amuc_0522	9.39e-183	508.0	COG0476@1|root,COG0476@2|Bacteria,46SGF@74201|Verrucomicrobia,2IU1E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
NEGHOLOK_00308	349741.Amuc_0523	1.18e-224	620.0	COG0517@1|root,COG0794@1|root,COG0517@2|Bacteria,COG0794@2|Bacteria,46S8G@74201|Verrucomicrobia,2ITHA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	SIS domain	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
NEGHOLOK_00309	349741.Amuc_0524	1.91e-192	533.0	2E0WZ@1|root,32WDX@2|Bacteria,46WD0@74201|Verrucomicrobia,2IUTB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00310	349741.Amuc_0525	2.76e-292	796.0	COG1657@1|root,COG1657@2|Bacteria,46U97@74201|Verrucomicrobia,2ITWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	4.2.1.129,5.4.99.17	ko:K06045	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans
NEGHOLOK_00311	349741.Amuc_0526	3.05e-109	314.0	COG2259@1|root,COG2259@2|Bacteria,46T2M@74201|Verrucomicrobia,2IUPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
NEGHOLOK_00312	349741.Amuc_0527	1.34e-201	558.0	COG1045@1|root,COG1045@2|Bacteria,46UPZ@74201|Verrucomicrobia,2IWKR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine acetyltransferase, N-terminal	-	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NEGHOLOK_00313	349741.Amuc_0528	2.46e-307	838.0	COG0014@1|root,COG0014@2|Bacteria,46SGA@74201|Verrucomicrobia,2ITYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NEGHOLOK_00314	349741.Amuc_0529	1.25e-179	503.0	COG0263@1|root,COG0263@2|Bacteria,46SWM@74201|Verrucomicrobia,2IU7N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NEGHOLOK_00315	349741.Amuc_0530	0.0	1333.0	COG0021@1|root,COG0021@2|Bacteria,46SHW@74201|Verrucomicrobia,2ITKK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
NEGHOLOK_00316	349741.Amuc_0531	0.0	1189.0	COG0782@1|root,COG1747@1|root,COG0782@2|Bacteria,COG1747@2|Bacteria,46S7F@74201|Verrucomicrobia,2ITY2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcription elongation factor, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	GreA_GreB,GreA_GreB_N
NEGHOLOK_00317	349741.Amuc_0532	1.89e-166	465.0	COG0152@1|root,COG0152@2|Bacteria,46YXR@74201|Verrucomicrobia,2ITRI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	SAICAR synthetase	-	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NEGHOLOK_00318	349741.Amuc_0533	6.74e-117	334.0	2AWY0@1|root,31NVN@2|Bacteria,46XM4@74201|Verrucomicrobia,2IW6B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00319	349741.Amuc_0534	0.0	1598.0	COG0046@1|root,COG0046@2|Bacteria,46S8Y@74201|Verrucomicrobia,2IUEK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
NEGHOLOK_00320	349741.Amuc_0535	1.3e-177	493.0	COG0047@1|root,COG0047@2|Bacteria,46T5R@74201|Verrucomicrobia,2IV5H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	CobB/CobQ-like glutamine amidotransferase domain	-	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
NEGHOLOK_00322	349741.Amuc_0537	2.24e-263	721.0	COG1363@1|root,COG1363@2|Bacteria,46SM3@74201|Verrucomicrobia,2IU2V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NEGHOLOK_00324	349741.Amuc_0539	0.0	1855.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	lacZ_17	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NEGHOLOK_00325	349741.Amuc_0540	5.06e-236	650.0	COG1077@1|root,COG1077@2|Bacteria,46SAA@74201|Verrucomicrobia,2ITYI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Actin	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NEGHOLOK_00326	349741.Amuc_0541	0.0	1009.0	COG1530@1|root,COG1530@2|Bacteria,46S5S@74201|Verrucomicrobia,2ITMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribonuclease E/G family	-	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G
NEGHOLOK_00327	349741.Amuc_0542	8.99e-277	756.0	COG1522@1|root,COG1522@2|Bacteria,46SDK@74201|Verrucomicrobia,2IU3G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00328	349741.Amuc_0543	1.28e-193	543.0	29NXF@1|root,309VJ@2|Bacteria,46X8M@74201|Verrucomicrobia,2IV0Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00329	349741.Amuc_0544	0.0	2114.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46Z1Z@74201|Verrucomicrobia,2IUA3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6
NEGHOLOK_00331	349741.Amuc_0546	4.52e-101	293.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	exbD2	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
NEGHOLOK_00332	349741.Amuc_0547	1.65e-113	326.0	COG0848@1|root,COG0848@2|Bacteria	2|Bacteria	U	biopolymer transport protein	aglS	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
NEGHOLOK_00333	349741.Amuc_0548	9.91e-171	478.0	COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IUVE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
NEGHOLOK_00334	349741.Amuc_0549	8.42e-149	419.0	COG0177@1|root,COG0177@2|Bacteria,46T2G@74201|Verrucomicrobia,2IU17@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
NEGHOLOK_00335	349741.Amuc_0550	1.39e-157	442.0	COG3584@1|root,COG3584@2|Bacteria,46VUB@74201|Verrucomicrobia,2IUCH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
NEGHOLOK_00336	349741.Amuc_0551	5.64e-228	628.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,2IU8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NEGHOLOK_00337	349741.Amuc_0552	4.1e-178	497.0	COG0134@1|root,COG0134@2|Bacteria,46V9B@74201|Verrucomicrobia,2ITZZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NEGHOLOK_00339	349741.Amuc_0553	4.83e-82	242.0	COG0792@1|root,COG0792@2|Bacteria,46T9J@74201|Verrucomicrobia,2IUV7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Uncharacterised protein family UPF0102	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NEGHOLOK_00340	349741.Amuc_0554	2.51e-151	425.0	COG0164@1|root,COG0164@2|Bacteria,46SXH@74201|Verrucomicrobia,2IU98@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Ribonuclease HII	-	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NEGHOLOK_00341	349741.Amuc_0555	4.77e-310	847.0	COG1253@1|root,COG1253@2|Bacteria,46SMD@74201|Verrucomicrobia,2IU23@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
NEGHOLOK_00342	349741.Amuc_0556	8.43e-59	181.0	2C1W8@1|root,2ZXK7@2|Bacteria,46WJJ@74201|Verrucomicrobia,2IUVQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
NEGHOLOK_00343	349741.Amuc_0557	2.79e-54	170.0	COG0199@1|root,COG0199@2|Bacteria,46TBH@74201|Verrucomicrobia,2IUM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NEGHOLOK_00345	349741.Amuc_0559	2.9e-316	860.0	COG0137@1|root,COG0137@2|Bacteria,46SCU@74201|Verrucomicrobia,2ITYG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Arginosuccinate synthase	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
NEGHOLOK_00346	595460.RRSWK_03587	1.05e-115	358.0	COG3119@1|root,COG3119@2|Bacteria,2IX0S@203682|Planctomycetes	203682|Planctomycetes	P	COG3119 Arylsulfatase A	-	-	3.1.6.8	ko:K01134	ko00600,ko04142,map00600,map04142	-	R04856	RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
NEGHOLOK_00347	349741.Amuc_0561	8.12e-302	822.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,46TY0@74201|Verrucomicrobia,2ITWQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	16S rRNA methyltransferase RsmB/F	-	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
NEGHOLOK_00348	349741.Amuc_0562	4.82e-178	496.0	COG0149@1|root,COG0149@2|Bacteria,46SNB@74201|Verrucomicrobia,2IU4R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
NEGHOLOK_00349	349741.Amuc_0563	9.08e-165	460.0	COG4968@1|root,COG4968@2|Bacteria	2|Bacteria	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_00350	349741.Amuc_0564	7.54e-143	403.0	2EEN4@1|root,338G1@2|Bacteria,46T5X@74201|Verrucomicrobia,2IUHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00351	349741.Amuc_0565	0.0	1072.0	COG3119@1|root,COG3119@2|Bacteria,46UNA@74201|Verrucomicrobia,2IV2G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
NEGHOLOK_00355	349741.Amuc_0568	2.03e-101	293.0	COG0824@1|root,COG0824@2|Bacteria,46T37@74201|Verrucomicrobia,2IUDB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Thioesterase-like superfamily	-	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT
NEGHOLOK_00356	349741.Amuc_0569	1.19e-180	502.0	COG1040@1|root,COG1040@2|Bacteria,46T0D@74201|Verrucomicrobia,2IUGQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	competence protein	-	-	-	-	-	-	-	-	-	-	-	-	Pribosyltran
NEGHOLOK_00357	349741.Amuc_0570	2.92e-70	211.0	29N4X@1|root,3092Q@2|Bacteria,46X7T@74201|Verrucomicrobia,2IUXE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00358	349741.Amuc_0571	4.15e-191	530.0	COG1694@1|root,COG3956@2|Bacteria,46SNM@74201|Verrucomicrobia,2ITIM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	MazG nucleotide pyrophosphohydrolase domain	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	MazG
NEGHOLOK_00359	349741.Amuc_0572	3.68e-75	224.0	2AVZM@1|root,31MU0@2|Bacteria,46X67@74201|Verrucomicrobia,2IUMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00360	349741.Amuc_0573	2.24e-264	723.0	COG0349@1|root,COG0349@2|Bacteria,46SUU@74201|Verrucomicrobia,2IU03@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	3'-5' exonuclease	-	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
NEGHOLOK_00362	349741.Amuc_0574	4.56e-139	396.0	COG1579@1|root,COG1579@2|Bacteria,46T10@74201|Verrucomicrobia,2IUE8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	C4-type zinc ribbon domain	-	-	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
NEGHOLOK_00363	349741.Amuc_0575	2.22e-298	813.0	COG1663@1|root,COG1663@2|Bacteria,46SBI@74201|Verrucomicrobia,2ITPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)	lpxK	-	2.7.1.130	ko:K00912	ko00540,ko01100,map00540,map01100	M00060	R04657	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	LpxK
NEGHOLOK_00364	349741.Amuc_0576	0.0	2841.0	COG0612@1|root,COG0612@2|Bacteria,46UTT@74201|Verrucomicrobia,2ITM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
NEGHOLOK_00365	1408437.JNJN01000017_gene2286	5.63e-78	238.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,25W0V@186806|Eubacteriaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
NEGHOLOK_00366	335541.Swol_0935	1.01e-151	434.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NEGHOLOK_00367	335541.Swol_0934	2.59e-134	388.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia	186801|Clostridia	E	5,10-methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NEGHOLOK_00368	717606.PaecuDRAFT_2383	0.0	986.0	COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli,26SEX@186822|Paenibacillaceae	91061|Bacilli	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	metE	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_1,Meth_synt_2
NEGHOLOK_00369	633149.Bresu_3216	0.000103	42.0	2DFC4@1|root,2ZR9S@2|Bacteria,1Q4M0@1224|Proteobacteria,2UNE4@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Entericidin EcnA/B family	-	-	-	-	-	-	-	-	-	-	-	-	Entericidin
NEGHOLOK_00371	349741.Amuc_0581	1.3e-206	572.0	COG0673@1|root,COG0673@2|Bacteria,46TDD@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	-	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C
NEGHOLOK_00372	349741.Amuc_0582	1.76e-175	489.0	COG3034@1|root,COG3034@2|Bacteria,46T6Y@74201|Verrucomicrobia,2IUG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	peptidoglycan biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_00373	349741.Amuc_0583	1.88e-136	385.0	COG4430@1|root,COG4430@2|Bacteria	2|Bacteria	F	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
NEGHOLOK_00374	349741.Amuc_1723	0.0	3560.0	COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria,46Z6U@74201|Verrucomicrobia	74201|Verrucomicrobia	S	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	PATR
NEGHOLOK_00375	349741.Amuc_0836	0.0	1571.0	COG0542@1|root,COG0542@2|Bacteria,46S4S@74201|Verrucomicrobia,2ITN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03695	ko04213,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NEGHOLOK_00377	349741.Amuc_0834	2.22e-231	636.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,MarR,MarR_2
NEGHOLOK_00378	349741.Amuc_0833	2.5e-79	235.0	COG1917@1|root,COG1917@2|Bacteria,46WJU@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Cupin 2 conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NEGHOLOK_00379	349741.Amuc_0832	6.76e-131	372.0	COG2156@1|root,COG2156@2|Bacteria,46SYC@74201|Verrucomicrobia,2IVFX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	-	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
NEGHOLOK_00380	349741.Amuc_0831	0.0	1302.0	COG2216@1|root,COG2216@2|Bacteria,46SEM@74201|Verrucomicrobia,2ITIQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	-	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
NEGHOLOK_00381	349741.Amuc_0830	0.0	1096.0	COG2060@1|root,COG2060@2|Bacteria,46S9Y@74201|Verrucomicrobia,2ITVE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	-	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
NEGHOLOK_00383	349741.Amuc_0828	2.4e-167	467.0	COG0745@1|root,COG0745@2|Bacteria,46UC4@74201|Verrucomicrobia,2IUBT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NEGHOLOK_00384	349741.Amuc_0827	0.0	1704.0	COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,2ITGS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
NEGHOLOK_00386	349741.Amuc_0952	5.7e-07	57.0	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00387	349741.Amuc_0824	0.0	2589.0	COG3250@1|root,COG3250@2|Bacteria,46XA3@74201|Verrucomicrobia,2IV61@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NEGHOLOK_00388	349741.Amuc_0823	2.53e-266	728.0	COG3528@1|root,COG3528@2|Bacteria,46WUE@74201|Verrucomicrobia,2IUWW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterized protein conserved in bacteria (DUF2219)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2219
NEGHOLOK_00389	349741.Amuc_0822	1.78e-202	559.0	COG0084@1|root,COG0084@2|Bacteria,46SKF@74201|Verrucomicrobia,2IU4S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NEGHOLOK_00390	349741.Amuc_0821	2.63e-84	251.0	COG1388@1|root,COG1388@2|Bacteria,46W1D@74201|Verrucomicrobia,2IUXD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NEGHOLOK_00391	349741.Amuc_0820	8.74e-180	499.0	COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_00392	349741.Amuc_0819	0.0	874.0	COG0534@1|root,COG0534@2|Bacteria,46XHB@74201|Verrucomicrobia,2IVXB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NEGHOLOK_00393	349741.Amuc_0818	1.05e-252	693.0	COG0499@1|root,COG0499@2|Bacteria	2|Bacteria	H	adenosylhomocysteinase activity	-	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase_NAD,NAD_binding_7,TrkA_N
NEGHOLOK_00395	349741.Amuc_0816	1.45e-258	709.0	COG0592@1|root,COG0592@2|Bacteria,46SPK@74201|Verrucomicrobia,2ITMH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	-	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NEGHOLOK_00397	349741.Amuc_0814	1.63e-156	443.0	COG1207@1|root,COG1207@2|Bacteria,46Z6P@74201|Verrucomicrobia,2IWPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NEGHOLOK_00398	349741.Amuc_0813	2.07e-262	718.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,46SFQ@74201|Verrucomicrobia,2ITYE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	RibD C-terminal domain	-	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
NEGHOLOK_00399	349741.Amuc_0812	0.0	1236.0	COG0445@1|root,COG0445@2|Bacteria,46SID@74201|Verrucomicrobia,2ITMA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NEGHOLOK_00400	349741.Amuc_0811	4.27e-273	748.0	COG1466@1|root,COG1466@2|Bacteria,46T5Y@74201|Verrucomicrobia,2ITP3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NEGHOLOK_00401	349741.Amuc_0810	0.0	952.0	COG0265@1|root,COG0265@2|Bacteria,46SHP@74201|Verrucomicrobia,2IU51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
NEGHOLOK_00402	349741.Amuc_0809	1.18e-109	315.0	COG0440@1|root,COG0440@2|Bacteria,46SUP@74201|Verrucomicrobia,2IU7V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NEGHOLOK_00403	349741.Amuc_0808	0.0	2461.0	COG1643@1|root,COG1643@2|Bacteria,46TFT@74201|Verrucomicrobia,2IU1J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Oligonucleotide/oligosaccharide-binding (OB)-fold	-	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
NEGHOLOK_00404	349741.Amuc_0807	3.52e-161	452.0	COG0569@1|root,COG0569@2|Bacteria,46W0A@74201|Verrucomicrobia,2IUXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NEGHOLOK_00405	349741.Amuc_0806	0.0	1145.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
NEGHOLOK_00406	904296.HMPREF9124_0277	8.16e-209	602.0	COG1479@1|root,COG1479@2|Bacteria,1UHG8@1239|Firmicutes,25BDT@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1524)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1524,DUF262
NEGHOLOK_00407	1165096.ARWF01000001_gene138	4.33e-17	75.5	COG1396@1|root,COG1396@2|Bacteria,1QWIH@1224|Proteobacteria	1224|Proteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NEGHOLOK_00409	349741.Amuc_0804	2.58e-178	497.0	COG0107@1|root,COG0107@2|Bacteria,46S6V@74201|Verrucomicrobia,2ITUS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NEGHOLOK_00410	349741.Amuc_0803	0.0	1456.0	COG3507@1|root,COG3934@1|root,COG3507@2|Bacteria,COG3934@2|Bacteria,46XDM@74201|Verrucomicrobia,2IVK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091,F5_F8_type_C
NEGHOLOK_00411	349741.Amuc_0802	3.2e-70	211.0	COG1733@1|root,COG1733@2|Bacteria,46Z1E@74201|Verrucomicrobia,2IUT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NEGHOLOK_00412	349741.Amuc_0801	1.32e-101	294.0	COG3837@1|root,COG3837@2|Bacteria	2|Bacteria	S	Cupin domain	manC	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NEGHOLOK_00413	349741.Amuc_0799	0.0	2385.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,46UWQ@74201|Verrucomicrobia,2IV57@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,PFOR_II,POR,POR_N,TPP_enzyme_C
NEGHOLOK_00414	349741.Amuc_0798	0.0	986.0	COG1190@1|root,COG1190@2|Bacteria,46TIA@74201|Verrucomicrobia,2ITHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NEGHOLOK_00415	349741.Amuc_0797	1.02e-187	521.0	COG0631@1|root,COG0631@2|Bacteria	2|Bacteria	T	protein serine/threonine phosphatase activity	pppL	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2,SpoIIE
NEGHOLOK_00416	349741.Amuc_0796	4.34e-152	427.0	COG0344@1|root,COG0344@2|Bacteria,46VTA@74201|Verrucomicrobia,2IUDC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Glycerol-3-phosphate acyltransferase	-	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NEGHOLOK_00417	349741.Amuc_0795	8.08e-236	649.0	COG0240@1|root,COG0240@2|Bacteria,46SQJ@74201|Verrucomicrobia,2ITRT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NEGHOLOK_00418	349741.Amuc_0794	8.62e-102	294.0	2FCQS@1|root,344TZ@2|Bacteria,46W38@74201|Verrucomicrobia,2IUKT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00420	349741.Amuc_0792	1.99e-263	720.0	COG0535@1|root,COG0535@2|Bacteria,46T4P@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART Elongator protein 3 MiaB NifB	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NEGHOLOK_00421	349741.Amuc_0791	1.32e-313	852.0	COG0535@1|root,COG0535@2|Bacteria,46T4P@74201|Verrucomicrobia	74201|Verrucomicrobia	C	SMART Elongator protein 3 MiaB NifB	pqqE	-	-	ko:K06139	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NEGHOLOK_00422	349741.Amuc_0790	0.0	869.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	2|Bacteria	E	Cys/Met metabolism PLP-dependent enzyme	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NEGHOLOK_00423	349741.Amuc_0952	4.94e-05	51.2	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00424	349741.Amuc_0788	0.0	1005.0	COG0606@1|root,COG0606@2|Bacteria,46SAK@74201|Verrucomicrobia,2ITTW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Magnesium chelatase, subunit ChlI C-terminal	-	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NEGHOLOK_00425	349741.Amuc_0787	2.36e-209	578.0	COG0705@1|root,COG0705@2|Bacteria,46W15@74201|Verrucomicrobia,2IUFI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NEGHOLOK_00426	349741.Amuc_0786	2.63e-269	734.0	COG0665@1|root,COG0665@2|Bacteria,46VX5@74201|Verrucomicrobia,2IUI6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
NEGHOLOK_00427	349741.Amuc_0785	2.64e-267	731.0	COG0473@1|root,COG0473@2|Bacteria,46S4R@74201|Verrucomicrobia,2ITY1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CE	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NEGHOLOK_00430	349741.Amuc_0783	0.0	901.0	COG3969@1|root,COG3969@2|Bacteria,46UDX@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Phosphoadenosine phosphosulfate reductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3440,PAPS_reduct
NEGHOLOK_00431	349741.Amuc_0782	2e-120	343.0	COG1475@1|root,COG1475@2|Bacteria,46VTE@74201|Verrucomicrobia	74201|Verrucomicrobia	K	ParB domain protein nuclease	-	-	-	-	-	-	-	-	-	-	-	-	ParBc
NEGHOLOK_00434	349741.Amuc_0779	9.17e-116	332.0	COG1525@1|root,COG1525@2|Bacteria,46X7M@74201|Verrucomicrobia,2IUVR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Staphylococcal nuclease homologues	-	-	-	-	-	-	-	-	-	-	-	-	SNase
NEGHOLOK_00435	349741.Amuc_0778	5.62e-247	677.0	2DB8U@1|root,2Z7SW@2|Bacteria,46VFK@74201|Verrucomicrobia,2IUK1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Alginate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Alginate_lyase
NEGHOLOK_00436	349741.Amuc_0777	1.79e-206	574.0	COG1028@1|root,COG1028@2|Bacteria,46SN5@74201|Verrucomicrobia,2IUJB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NEGHOLOK_00439	349741.Amuc_0775	7.17e-104	300.0	COG1607@1|root,COG1607@2|Bacteria	2|Bacteria	I	acyl-coa hydrolase	yciA	-	-	ko:K10806	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT
NEGHOLOK_00440	349741.Amuc_0774	1.42e-315	862.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	hsrA	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
NEGHOLOK_00441	349741.Amuc_0773	1.72e-290	791.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_00442	349741.Amuc_0772	1.38e-241	674.0	COG0588@1|root,COG1052@1|root,COG0588@2|Bacteria,COG1052@2|Bacteria,46SGM@74201|Verrucomicrobia,2ITY0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NEGHOLOK_00443	349741.Amuc_0772	1.3e-180	516.0	COG0588@1|root,COG1052@1|root,COG0588@2|Bacteria,COG1052@2|Bacteria,46SGM@74201|Verrucomicrobia,2ITY0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NEGHOLOK_00444	349741.Amuc_0771	0.0	1354.0	COG1874@1|root,COG1874@2|Bacteria,46UVE@74201|Verrucomicrobia,2IU38@203494|Verrucomicrobiae	2|Bacteria	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	BetaGal_dom4_5,Glyco_hydro_35
NEGHOLOK_00446	349741.Amuc_0770	8.77e-158	442.0	COG0778@1|root,COG0778@2|Bacteria,46WEH@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NEGHOLOK_00447	349741.Amuc_0769	0.0	1349.0	COG1305@1|root,COG1305@2|Bacteria,46VXQ@74201|Verrucomicrobia,2IUIY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00448	349741.Amuc_0768	6.8e-111	320.0	COG0663@1|root,COG0663@2|Bacteria,46V7F@74201|Verrucomicrobia,2IU9X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NEGHOLOK_00449	349741.Amuc_0767	6.56e-112	321.0	COG1259@1|root,COG1259@2|Bacteria,46SW6@74201|Verrucomicrobia,2IUQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
NEGHOLOK_00451	349741.Amuc_0766	0.0	1157.0	COG0471@1|root,COG0490@1|root,COG0471@2|Bacteria,COG0490@2|Bacteria,46UA9@74201|Verrucomicrobia,2ITKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp,TrkA_C
NEGHOLOK_00453	349741.Amuc_0762	8.04e-258	705.0	28IIB@1|root,30IUU@2|Bacteria,46V5V@74201|Verrucomicrobia,2IWAJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
NEGHOLOK_00454	349741.Amuc_0761	0.0	1435.0	COG1835@1|root,COG1835@2|Bacteria,46X8A@74201|Verrucomicrobia,2IUZP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_00455	349741.Amuc_0760	1.74e-251	688.0	28IN0@1|root,2Z8NG@2|Bacteria,46W43@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Glycosyltransferase family 10 (fucosyltransferase) C-term	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_10
NEGHOLOK_00456	349741.Amuc_0759	7.13e-310	845.0	COG0438@1|root,COG0438@2|Bacteria,46W11@74201|Verrucomicrobia,2IW0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4
NEGHOLOK_00457	349741.Amuc_0758	1.03e-204	565.0	2A4B8@1|root,30SWV@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00458	349741.Amuc_0757	2.25e-287	783.0	COG0463@1|root,COG0463@2|Bacteria,46Z6N@74201|Verrucomicrobia,2IW83@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_00459	349741.Amuc_0756	2.26e-245	672.0	COG0451@1|root,COG0451@2|Bacteria,46TV3@74201|Verrucomicrobia,2IVB1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	5.1.3.20	ko:K03274	ko00540,ko01100,map00540,map01100	M00064	R05176	RC01291	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase
NEGHOLOK_00460	349741.Amuc_0755	3.86e-235	646.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	-	-	-	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_tran_WbsX,Glyco_transf_9
NEGHOLOK_00461	349741.Amuc_0754	6.79e-249	682.0	COG1216@1|root,COG1216@2|Bacteria,46TK6@74201|Verrucomicrobia,2IUYU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_00462	349741.Amuc_0753	4.53e-244	669.0	COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
NEGHOLOK_00463	349741.Amuc_0752	4.39e-209	577.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxG	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NEGHOLOK_00465	349741.Amuc_0750	7.27e-242	664.0	COG0618@1|root,COG0618@2|Bacteria,46T03@74201|Verrucomicrobia,2ITUW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DHHA1 domain	-	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NEGHOLOK_00466	349741.Amuc_0749	9.36e-171	477.0	COG0130@1|root,COG0130@2|Bacteria,46SJR@74201|Verrucomicrobia,2ITQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C_2,TruB_N
NEGHOLOK_00467	349741.Amuc_0748	2.87e-219	605.0	COG0196@1|root,COG0196@2|Bacteria,46SZ6@74201|Verrucomicrobia,2IU48@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Riboflavin kinase	-	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NEGHOLOK_00468	349741.Amuc_0747	9e-65	197.0	COG0853@1|root,COG0853@2|Bacteria,46W3T@74201|Verrucomicrobia,2IUIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
NEGHOLOK_00469	349741.Amuc_0746	8.9e-82	244.0	COG1314@1|root,COG1314@2|Bacteria,46T75@74201|Verrucomicrobia,2IUIB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
NEGHOLOK_00470	349741.Amuc_0745	1.15e-151	426.0	COG4969@1|root,COG4969@2|Bacteria,46ZJH@74201|Verrucomicrobia,2IUWI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_00471	349741.Amuc_0744	6.87e-256	701.0	COG0722@1|root,COG0722@2|Bacteria,46TIT@74201|Verrucomicrobia,2IU3E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
NEGHOLOK_00472	349741.Amuc_0743	1.06e-127	362.0	2EMM1@1|root,33F9E@2|Bacteria,46TBT@74201|Verrucomicrobia,2IUX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00473	349741.Amuc_0742	1.02e-232	640.0	COG0679@1|root,COG0679@2|Bacteria,46SPM@74201|Verrucomicrobia,2IUBD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NEGHOLOK_00474	349741.Amuc_0741	2.89e-173	484.0	COG1432@1|root,COG1432@2|Bacteria,46SBH@74201|Verrucomicrobia,2IURP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
NEGHOLOK_00475	349741.Amuc_0740	2.15e-151	425.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	ppaX_1	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NEGHOLOK_00476	349741.Amuc_0739	1.58e-138	392.0	COG0110@1|root,COG0110@2|Bacteria,46TEB@74201|Verrucomicrobia,2IUHQ@203494|Verrucomicrobiae	74201|Verrucomicrobia	S	Maltose acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Mac
NEGHOLOK_00477	349741.Amuc_0738	0.0	1020.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,46SIW@74201|Verrucomicrobia,2ITUH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	GMP synthase C terminal domain	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
NEGHOLOK_00478	349741.Amuc_0737	0.0	928.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,46W51@74201|Verrucomicrobia,2ITJ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
NEGHOLOK_00479	349741.Amuc_0736	1.43e-120	344.0	COG0394@1|root,COG0394@2|Bacteria,46VNK@74201|Verrucomicrobia,2IUIM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NEGHOLOK_00480	349741.Amuc_0735	0.0	3225.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_00482	349741.Amuc_0731	5.94e-266	726.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
NEGHOLOK_00483	349741.Amuc_0730	1.81e-253	694.0	COG1181@1|root,COG1181@2|Bacteria	2|Bacteria	F	Belongs to the D-alanine--D-alanine ligase family	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NEGHOLOK_00484	349741.Amuc_0729	8.14e-286	780.0	COG2334@1|root,COG2334@2|Bacteria,46Z6M@74201|Verrucomicrobia,2IU0S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
NEGHOLOK_00485	349741.Amuc_0728	3.23e-253	694.0	COG0536@1|root,COG0536@2|Bacteria,46SBS@74201|Verrucomicrobia,2ITSD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	GTP1_OBG,MMR_HSR1
NEGHOLOK_00487	349741.Amuc_0726	7.86e-138	390.0	COG1716@1|root,COG1716@2|Bacteria	2|Bacteria	T	histone H2A K63-linked ubiquitination	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388,FHA,Yop-YscD_cpl
NEGHOLOK_00488	349741.Amuc_0725	1.39e-130	370.0	COG0350@1|root,COG0350@2|Bacteria,46T3E@74201|Verrucomicrobia,2IUK7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
NEGHOLOK_00489	349741.Amuc_0724	5.11e-222	611.0	COG2273@1|root,COG2273@2|Bacteria,46UCB@74201|Verrucomicrobia,2IUFQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
NEGHOLOK_00490	349741.Amuc_0723	8.55e-214	589.0	COG0115@1|root,COG0115@2|Bacteria,46S9W@74201|Verrucomicrobia,2ITHT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NEGHOLOK_00491	349741.Amuc_0722	0.0	1216.0	COG1217@1|root,COG1217@2|Bacteria,46SHA@74201|Verrucomicrobia,2ITJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Elongation factor G C-terminus	-	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
NEGHOLOK_00492	349741.Amuc_0721	1.32e-235	649.0	COG0191@1|root,COG0191@2|Bacteria,46UMQ@74201|Verrucomicrobia,2ITR6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Fructose-bisphosphate aldolase class-II	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NEGHOLOK_00493	349741.Amuc_0720	3.97e-313	852.0	COG0019@1|root,COG0019@2|Bacteria,46SC5@74201|Verrucomicrobia,2ITWM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NEGHOLOK_00494	349741.Amuc_0719	6.62e-257	705.0	COG0628@1|root,COG0628@2|Bacteria,46U8S@74201|Verrucomicrobia,2IU6H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AI-2E family transporter	-	-	-	ko:K11744	-	-	-	-	ko00000	-	-	-	AI-2E_transport
NEGHOLOK_00495	349741.Amuc_0718	1.98e-156	439.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	gph	-	3.1.3.18,3.6.1.1	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NEGHOLOK_00496	349741.Amuc_0717	1.14e-294	806.0	COG0531@1|root,COG0531@2|Bacteria,46W3Q@74201|Verrucomicrobia,2IWAN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NEGHOLOK_00497	349741.Amuc_0716	2.02e-173	485.0	COG2022@1|root,COG2022@2|Bacteria,46SHY@74201|Verrucomicrobia,2ITYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Thiazole biosynthesis protein ThiG	-	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NEGHOLOK_00499	349741.Amuc_0714	1.79e-201	563.0	COG4864@1|root,COG4864@2|Bacteria,46TWZ@74201|Verrucomicrobia,2ITH8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SigmaW regulon antibacterial	-	-	-	-	-	-	-	-	-	-	-	-	YdfA_immunity
NEGHOLOK_00500	349741.Amuc_0713	7.86e-242	664.0	COG0809@1|root,COG0809@2|Bacteria,46SDA@74201|Verrucomicrobia,2IU22@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
NEGHOLOK_00502	349741.Amuc_0711	0.0	1046.0	COG1226@1|root,COG4651@1|root,COG1226@2|Bacteria,COG4651@2|Bacteria,46UN8@74201|Verrucomicrobia,2IV26@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
NEGHOLOK_00503	349741.Amuc_0710	0.0	924.0	COG0053@1|root,COG0053@2|Bacteria,46SPJ@74201|Verrucomicrobia,2IUZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Dimerisation domain of Zinc Transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NEGHOLOK_00504	349741.Amuc_0709	5.84e-173	483.0	COG0217@1|root,COG0217@2|Bacteria,46SP3@74201|Verrucomicrobia,2IU5Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NEGHOLOK_00505	349741.Amuc_0708	0.0	1151.0	COG1158@1|root,COG1158@2|Bacteria,46UQY@74201|Verrucomicrobia,2ITRJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
NEGHOLOK_00506	349741.Amuc_0707	4.88e-169	471.0	COG0602@1|root,COG0602@2|Bacteria,46SW0@74201|Verrucomicrobia,2IUF0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds	-	-	4.3.99.3	ko:K10026	ko00790,ko01100,map00790,map01100	-	R10002	RC02989	ko00000,ko00001,ko01000,ko03016	-	-	-	Fer4_14,Radical_SAM
NEGHOLOK_00507	349741.Amuc_0706	2.69e-181	512.0	COG4372@1|root,COG4372@2|Bacteria	2|Bacteria	Q	Transposase	-	-	2.7.13.3	ko:K07777	ko02020,map02020	M00478	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	EzrA
NEGHOLOK_00508	349741.Amuc_0705	0.0	1030.0	COG0111@1|root,COG0111@2|Bacteria,46Z6K@74201|Verrucomicrobia,2ITN1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
NEGHOLOK_00509	349741.Amuc_0704	2.2e-313	852.0	COG4198@1|root,COG4198@2|Bacteria,46S83@74201|Verrucomicrobia,2IV8W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NEGHOLOK_00510	349741.Amuc_0703	6.99e-238	655.0	COG0075@1|root,COG0075@2|Bacteria,46SCI@74201|Verrucomicrobia,2IU5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NEGHOLOK_00511	349741.Amuc_0702	5.45e-234	645.0	COG2855@1|root,COG2855@2|Bacteria,46WQA@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Conserved hypothetical protein 698	-	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
NEGHOLOK_00512	349741.Amuc_0701	2.58e-214	593.0	COG0583@1|root,COG0583@2|Bacteria,46SDJ@74201|Verrucomicrobia,2IU8Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NEGHOLOK_00515	349741.Amuc_0698	6.92e-288	783.0	COG3507@1|root,COG3507@2|Bacteria,46Z6J@74201|Verrucomicrobia,2IV24@203494|Verrucomicrobiae	2|Bacteria	M	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_43,RicinB_lectin_2
NEGHOLOK_00516	349741.Amuc_0697	1.31e-153	437.0	COG3507@1|root,COG3507@2|Bacteria,46Z6J@74201|Verrucomicrobia,2IV24@203494|Verrucomicrobiae	2|Bacteria	M	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_43,RicinB_lectin_2
NEGHOLOK_00517	349741.Amuc_0696	0.0	863.0	COG1657@1|root,COG1657@2|Bacteria,46XAC@74201|Verrucomicrobia,2IV6H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00518	349741.Amuc_0695	2.41e-301	821.0	COG1657@1|root,COG1657@2|Bacteria,46XAC@74201|Verrucomicrobia,2IV6H@203494|Verrucomicrobiae	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576	4.2.1.129,5.4.99.17,5.5.1.16	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	-	R07322,R07323	RC01850,RC01851	ko00000,ko00001,ko01000	-	-	-	Prenyltrans,SQHop_cyclase_C
NEGHOLOK_00519	349741.Amuc_0694	1.98e-261	719.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02022	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD,HlyD_3
NEGHOLOK_00520	349741.Amuc_0693	2.49e-157	441.0	COG4262@1|root,COG4262@2|Bacteria,46Z6I@74201|Verrucomicrobia,2IVWZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00522	349741.Amuc_0691	5.12e-71	213.0	COG3118@1|root,COG3118@2|Bacteria,46VWK@74201|Verrucomicrobia,2IUMX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NEGHOLOK_00523	349741.Amuc_0690	5.48e-296	808.0	COG3271@1|root,COG3271@2|Bacteria,46WD7@74201|Verrucomicrobia,2IUDZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00524	349741.Amuc_0689	0.0	914.0	COG0017@1|root,COG0017@2|Bacteria,46TN6@74201|Verrucomicrobia,2ITHF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class II (D, K and N)	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NEGHOLOK_00526	349741.Amuc_0687	0.0	1802.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
NEGHOLOK_00527	349741.Amuc_0686	0.0	1643.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia,2IVCC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
NEGHOLOK_00528	349741.Amuc_0685	4.38e-113	325.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	ywrF	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NEGHOLOK_00529	349741.Amuc_0684	2.27e-86	253.0	COG1733@1|root,COG1733@2|Bacteria,46Z1E@74201|Verrucomicrobia,2IUT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NEGHOLOK_00530	349741.Amuc_0683	0.0	1321.0	COG0210@1|root,COG0210@2|Bacteria,46S8H@74201|Verrucomicrobia,2ITJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NEGHOLOK_00531	349741.Amuc_0682	1.27e-305	834.0	COG2885@1|root,COG2885@2|Bacteria,46ZBB@74201|Verrucomicrobia,2IU9R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
NEGHOLOK_00532	349741.Amuc_0681	0.0	907.0	COG0773@1|root,COG0773@2|Bacteria,46THM@74201|Verrucomicrobia,2ITID@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mur ligase family, catalytic domain	-	-	6.3.2.45	ko:K02558	-	-	-	-	ko00000,ko01000	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NEGHOLOK_00533	349741.Amuc_0680	6.55e-221	608.0	COG0560@1|root,COG0560@2|Bacteria,46UCT@74201|Verrucomicrobia,2ITII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Phosphoserine phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
NEGHOLOK_00534	349741.Amuc_0679	6.31e-171	478.0	COG1137@1|root,COG1137@2|Bacteria,46SDI@74201|Verrucomicrobia,2IU2S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K06861	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	1.B.42.1	-	-	ABC_tran
NEGHOLOK_00537	349741.Amuc_0676	2.72e-197	546.0	COG2877@1|root,COG2877@2|Bacteria,46SMZ@74201|Verrucomicrobia,2IU2C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	DAHP synthetase I family	-	-	2.5.1.55	ko:K01627	ko00540,ko01100,map00540,map01100	M00063	R03254	RC00435	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	DAHP_synth_1
NEGHOLOK_00538	349741.Amuc_0675	1.86e-171	479.0	COG2138@1|root,COG2138@2|Bacteria	2|Bacteria	S	sirohydrochlorin cobaltochelatase activity	cbiX	-	4.99.1.3	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiX
NEGHOLOK_00539	349741.Amuc_0674	5.88e-163	456.0	COG0052@1|root,COG0052@2|Bacteria,46SNG@74201|Verrucomicrobia,2ITPQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S2	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NEGHOLOK_00540	349741.Amuc_0673	2.05e-198	551.0	COG0264@1|root,COG0264@2|Bacteria,46SUK@74201|Verrucomicrobia,2IU52@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NEGHOLOK_00541	349741.Amuc_0672	7.6e-174	486.0	COG4608@1|root,COG4608@2|Bacteria,46SHJ@74201|Verrucomicrobia,2ITZ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NEGHOLOK_00543	349741.Amuc_0671	7.19e-281	767.0	COG0337@1|root,COG0337@2|Bacteria,46UQ7@74201|Verrucomicrobia,2ITKA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	3-dehydroquinate synthase	-	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NEGHOLOK_00544	349741.Amuc_0670	0.0	983.0	COG0265@1|root,COG0265@2|Bacteria,46SZ1@74201|Verrucomicrobia,2ITZC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
NEGHOLOK_00545	349741.Amuc_0669	0.0	1040.0	COG0265@1|root,COG0265@2|Bacteria,46UAN@74201|Verrucomicrobia,2ITY6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
NEGHOLOK_00546	349741.Amuc_0668	4.99e-274	749.0	2E1EI@1|root,32WTG@2|Bacteria,46T04@74201|Verrucomicrobia,2IUNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00547	349741.Amuc_0667	3.6e-145	409.0	COG0066@1|root,COG0066@2|Bacteria,46TAY@74201|Verrucomicrobia,2IU7P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aconitase C-terminal domain	-	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NEGHOLOK_00548	349741.Amuc_0666	0.0	943.0	COG0065@1|root,COG0065@2|Bacteria,46SUM@74201|Verrucomicrobia,2ITJH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aconitase family (aconitate hydratase)	-	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
NEGHOLOK_00549	349741.Amuc_0665	7.14e-141	399.0	COG0321@1|root,COG0321@2|Bacteria,46T11@74201|Verrucomicrobia,2IUBF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	2.3.1.181	ko:K03801	ko00785,ko01100,map00785,map01100	-	R07766,R07769	RC00039,RC00992,RC02867	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
NEGHOLOK_00550	349741.Amuc_0664	1.92e-238	656.0	COG0860@1|root,COG0860@2|Bacteria,46SS7@74201|Verrucomicrobia,2IU3W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Ami_3	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NEGHOLOK_00551	349741.Amuc_0663	1.15e-238	657.0	COG0468@1|root,COG0468@2|Bacteria,46SIZ@74201|Verrucomicrobia,2ITWB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NEGHOLOK_00552	349741.Amuc_0662	2.1e-215	594.0	COG1589@1|root,COG1589@2|Bacteria,46T4T@74201|Verrucomicrobia,2IUSI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	POTRA domain, FtsQ-type	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	POTRA_1
NEGHOLOK_00553	349741.Amuc_0661	4.13e-228	627.0	COG1181@1|root,COG1181@2|Bacteria,46UZ2@74201|Verrucomicrobia,2IU29@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NEGHOLOK_00554	349741.Amuc_0660	0.0	1513.0	COG0773@1|root,COG0812@1|root,COG0773@2|Bacteria,COG0812@2|Bacteria,46SCG@74201|Verrucomicrobia,2ITNT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain	murB	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_4,MurB_C,Mur_ligase,Mur_ligase_C,Mur_ligase_M
NEGHOLOK_00555	349741.Amuc_0659	5.55e-267	731.0	COG0707@1|root,COG0707@2|Bacteria,46S84@74201|Verrucomicrobia,2ITPN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	-	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NEGHOLOK_00556	349741.Amuc_0658	1.33e-277	758.0	COG0772@1|root,COG0772@2|Bacteria,46SMC@74201|Verrucomicrobia,2ITN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Cell cycle protein	-	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NEGHOLOK_00557	349741.Amuc_0657	1e-160	453.0	COG1388@1|root,COG1388@2|Bacteria	2|Bacteria	M	LysM domain	mltD	-	-	ko:K08307,ko:K12204,ko:K19224	-	-	-	-	ko00000,ko01000,ko01002,ko01011,ko02044	3.A.7.10.1,3.A.7.9.1	CBM50	-	LysM,NLPC_P60,SLT,T4SS_TraI
NEGHOLOK_00558	349741.Amuc_0656	1.45e-314	857.0	COG0771@1|root,COG0771@2|Bacteria,46UUH@74201|Verrucomicrobia,2ITN5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NEGHOLOK_00559	349741.Amuc_0655	8.1e-261	715.0	COG0472@1|root,COG0472@2|Bacteria,46SD0@74201|Verrucomicrobia,2ITSQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NEGHOLOK_00560	349741.Amuc_0654	0.0	897.0	COG0770@1|root,COG0770@2|Bacteria,46SDF@74201|Verrucomicrobia,2ITUQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mur ligase middle domain	-	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NEGHOLOK_00561	349741.Amuc_0653	0.0	990.0	COG0769@1|root,COG0769@2|Bacteria,46SGG@74201|Verrucomicrobia,2ITRP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NEGHOLOK_00562	349741.Amuc_0652	0.0	1372.0	COG0768@1|root,COG0768@2|Bacteria,46SEZ@74201|Verrucomicrobia,2ITJE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
NEGHOLOK_00564	349741.Amuc_0650	0.0	1009.0	COG0275@1|root,COG0275@2|Bacteria,46SPT@74201|Verrucomicrobia,2IU2A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NEGHOLOK_00565	349741.Amuc_0649	4.54e-105	303.0	COG2001@1|root,COG2001@2|Bacteria,46X89@74201|Verrucomicrobia,2IUZJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Belongs to the MraZ family	-	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	-
NEGHOLOK_00566	349741.Amuc_0648	5.27e-189	524.0	COG1235@1|root,COG1235@2|Bacteria,46SKU@74201|Verrucomicrobia,2IU55@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
NEGHOLOK_00567	349741.Amuc_0647	2.82e-154	433.0	COG2860@1|root,COG2860@2|Bacteria,46T5E@74201|Verrucomicrobia,2IUJG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	UPF0126 domain	-	-	-	-	-	-	-	-	-	-	-	-	UPF0126
NEGHOLOK_00568	457424.BFAG_04493	3.95e-13	77.4	2EN5K@1|root,33FTI@2|Bacteria,4P0E9@976|Bacteroidetes,2FU3G@200643|Bacteroidia	976|Bacteroidetes	S	Mac 1	-	-	-	-	-	-	-	-	-	-	-	-	Mac-1,Mfa_like_1
NEGHOLOK_00569	349741.Amuc_0645	8.07e-314	856.0	COG0486@1|root,COG0486@2|Bacteria,46SIQ@74201|Verrucomicrobia,2ITV2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NEGHOLOK_00570	349741.Amuc_0644	2.72e-263	720.0	COG0482@1|root,COG0482@2|Bacteria,46SQW@74201|Verrucomicrobia,2ITRY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NEGHOLOK_00571	349741.Amuc_0643	0.0	1084.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,HisKA_7TM,Hpt,PMT_2,Response_reg
NEGHOLOK_00572	349741.Amuc_0642	1.47e-208	577.0	COG0324@1|root,COG0324@2|Bacteria,46T1C@74201|Verrucomicrobia,2IU70@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NEGHOLOK_00573	349741.Amuc_0641	2.94e-184	511.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_00574	349741.Amuc_0640	1.04e-272	745.0	COG4763@1|root,COG4763@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NEGHOLOK_00575	349741.Amuc_0639	8.79e-143	403.0	COG0110@1|root,COG0110@2|Bacteria,46T6H@74201|Verrucomicrobia,2IW2C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Hexapeptide repeat of succinyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00576	349741.Amuc_0638	1.64e-283	773.0	COG0438@1|root,COG0438@2|Bacteria,46TH7@74201|Verrucomicrobia,2IVWS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
NEGHOLOK_00577	349741.Amuc_0637	6.99e-290	793.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NEGHOLOK_00578	349741.Amuc_0636	0.0	1022.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
NEGHOLOK_00580	349741.Amuc_0634	1.36e-244	669.0	COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
NEGHOLOK_00581	349741.Amuc_0633	1.5e-254	697.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_00582	349741.Amuc_0632	1.98e-259	710.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	MA20_42350	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glycos_transf_2
NEGHOLOK_00583	349741.Amuc_0631	1.29e-282	771.0	COG0369@1|root,COG0369@2|Bacteria,46SEE@74201|Verrucomicrobia,2ITWD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FAD binding domain	-	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
NEGHOLOK_00584	349741.Amuc_0630	9.5e-239	657.0	COG0332@1|root,COG0332@2|Bacteria,46SE2@74201|Verrucomicrobia,2ITMR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
NEGHOLOK_00585	349741.Amuc_0629	5.47e-243	670.0	COG2255@1|root,COG2255@2|Bacteria,46SDS@74201|Verrucomicrobia,2ITRW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NEGHOLOK_00588	441769.ABFU01000059_gene381	1e-116	345.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli,1ZBQM@1386|Bacillus	91061|Bacilli	L	DNA (cytosine-5-)-methyltransferase activity	-	GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008168,GO:0009307,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0032776,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044728,GO:0046483,GO:0050896,GO:0071704,GO:0090304,GO:0099046,GO:1901360	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase,N6_N4_Mtase
NEGHOLOK_00589	43989.cce_4746	1.43e-63	214.0	28JYK@1|root,2Z9NT@2|Bacteria,1G0XU@1117|Cyanobacteria	1117|Cyanobacteria	L	PFAM Restriction endonuclease, type II, HindVP	-	-	-	-	-	-	-	-	-	-	-	-	RE_HindVP
NEGHOLOK_00592	1173022.Cri9333_2755	4.82e-25	106.0	COG3440@1|root,COG3440@2|Bacteria,1G7DH@1117|Cyanobacteria	1117|Cyanobacteria	V	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_2,Pentapeptide
NEGHOLOK_00593	349741.Amuc_0627	0.0	1032.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	M60-like_N,Peptidase_M60,SBP_bac_5
NEGHOLOK_00594	349741.Amuc_0625	1.19e-315	858.0	COG4409@1|root,COG4409@2|Bacteria,46VEC@74201|Verrucomicrobia,2IUCZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	BNR/Asp-box repeat	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2
NEGHOLOK_00595	349741.Amuc_0621	2.28e-79	235.0	COG2076@1|root,COG2076@2|Bacteria,46W4K@74201|Verrucomicrobia,2IUY0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Small Multidrug Resistance protein	-	-	-	ko:K11741	-	-	-	-	ko00000,ko02000	2.A.7.1	-	-	Multi_Drug_Res
NEGHOLOK_00596	349741.Amuc_0620	0.0	1283.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,46S9D@74201|Verrucomicrobia,2IUJE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NEGHOLOK_00597	349741.Amuc_0618	1.05e-79	241.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NEGHOLOK_00598	349741.Amuc_0618	7.99e-75	228.0	COG0500@1|root,COG0500@2|Bacteria	2|Bacteria	Q	methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NEGHOLOK_00600	349741.Amuc_0616	4.82e-137	393.0	COG0631@1|root,COG0631@2|Bacteria,46UCG@74201|Verrucomicrobia,2IWMM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C_2
NEGHOLOK_00601	349741.Amuc_0615	0.0	2082.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	2|Bacteria	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_0661	CPSase_L_D2,CPSase_L_D3,MGS
NEGHOLOK_00602	349741.Amuc_0614	6.13e-194	537.0	29JAD@1|root,3067W@2|Bacteria,46VPD@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00603	349741.Amuc_0613	1.41e-120	344.0	COG3663@1|root,COG3663@2|Bacteria	2|Bacteria	L	G/U mismatch-specific uracil-DNA glycosylase activity	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NEGHOLOK_00604	349741.Amuc_0612	6.3e-224	618.0	COG0470@1|root,COG0470@2|Bacteria,46T6T@74201|Verrucomicrobia,2IU8J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III, delta subunit	-	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NEGHOLOK_00605	349741.Amuc_0611	2.88e-116	332.0	COG0139@1|root,COG0139@2|Bacteria,46SZA@74201|Verrucomicrobia,2IUFX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Phosphoribosyl-AMP cyclohydrolase	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
NEGHOLOK_00606	349741.Amuc_0610	1.18e-170	483.0	COG1729@1|root,COG4105@1|root,COG1729@2|Bacteria,COG4105@2|Bacteria,46SYU@74201|Verrucomicrobia,2IUQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Outer membrane lipoprotein	-	-	-	ko:K05807	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	TPR_6,YfiO
NEGHOLOK_00607	349741.Amuc_0609	7.51e-116	332.0	2EM72@1|root,33EW9@2|Bacteria,46TAB@74201|Verrucomicrobia,2IUQI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Lipopolysaccharide-assembly	-	-	-	-	-	-	-	-	-	-	-	-	LptE
NEGHOLOK_00608	349741.Amuc_0608	1.19e-163	458.0	COG0313@1|root,COG0313@2|Bacteria,46SVC@74201|Verrucomicrobia,2IU7K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NEGHOLOK_00609	349741.Amuc_0607	3.77e-181	506.0	COG3568@1|root,COG3568@2|Bacteria,46X7C@74201|Verrucomicrobia,2IUUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
NEGHOLOK_00610	1396141.BATP01000045_gene1776	2.72e-18	80.1	2FK8F@1|root,34BW5@2|Bacteria,46WAI@74201|Verrucomicrobia,2IUTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00611	349741.Amuc_0599	0.0	913.0	COG3746@1|root,COG3746@2|Bacteria,46T78@74201|Verrucomicrobia,2IUW9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Phosphate-selective porin O and P	-	-	-	ko:K07221	-	-	-	-	ko00000,ko02000	1.B.5.1	-	-	Porin_O_P
NEGHOLOK_00612	349741.Amuc_0598	2.4e-162	454.0	COG0571@1|root,COG0571@2|Bacteria,46T3X@74201|Verrucomicrobia,2IU7S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NEGHOLOK_00613	521674.Plim_3524	2.54e-39	149.0	COG4823@1|root,COG4823@2|Bacteria	2|Bacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
NEGHOLOK_00614	349741.Amuc_0597	3.15e-121	347.0	COG1853@1|root,COG1853@2|Bacteria	2|Bacteria	S	FMN binding	actI	-	1.5.1.36	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	-	R02698,R03299,R05705,R09748,R09750	RC00046,RC00126	ko00000,ko00001,ko01000	-	-	-	Flavin_Reduct
NEGHOLOK_00615	349741.Amuc_0596	9.06e-259	708.0	COG1195@1|root,COG1195@2|Bacteria,46UKV@74201|Verrucomicrobia,2IUBX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NEGHOLOK_00616	349741.Amuc_0595	8.17e-147	413.0	COG0204@1|root,COG0204@2|Bacteria,46SYR@74201|Verrucomicrobia,2IUG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NEGHOLOK_00617	349741.Amuc_0594	2.8e-143	405.0	COG0283@1|root,COG0283@2|Bacteria,46VD5@74201|Verrucomicrobia,2IUAI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Cytidylate kinase	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NEGHOLOK_00618	349741.Amuc_0593	0.0	1219.0	COG0204@1|root,COG3176@1|root,COG0204@2|Bacteria,COG3176@2|Bacteria,46U4X@74201|Verrucomicrobia,2IU47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_5,Acyltransferase
NEGHOLOK_00619	349741.Amuc_0592	4.91e-209	578.0	COG0611@1|root,COG0611@2|Bacteria,46SV7@74201|Verrucomicrobia,2IU3R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	thiL	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NEGHOLOK_00620	349741.Amuc_0591	1.77e-201	558.0	COG1266@1|root,COG1266@2|Bacteria,46T6D@74201|Verrucomicrobia,2IUVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NEGHOLOK_00621	349741.Amuc_0590	0.0	926.0	COG1940@1|root,COG1940@2|Bacteria,46SBQ@74201|Verrucomicrobia,2IV14@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GK	carbohydrate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00622	349741.Amuc_0589	0.0	1628.0	COG0515@1|root,COG0515@2|Bacteria,46TX9@74201|Verrucomicrobia,2ITS0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NEGHOLOK_00624	349741.Amuc_0587	2.66e-290	795.0	COG2262@1|root,COG2262@2|Bacteria,46SP4@74201|Verrucomicrobia,2IU26@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NEGHOLOK_00625	349741.Amuc_0586	1.37e-129	368.0	COG0424@1|root,COG0424@2|Bacteria,46VD8@74201|Verrucomicrobia,2IWJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Maf-like protein	-	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NEGHOLOK_00626	349741.Amuc_0585	0.0	1072.0	COG1171@1|root,COG1171@2|Bacteria,46S65@74201|Verrucomicrobia,2ITYU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_dehydrat_C
NEGHOLOK_00635	349741.Amuc_1285	0.0	1657.0	COG0187@1|root,COG0187@2|Bacteria,46SDH@74201|Verrucomicrobia,2IU0E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NEGHOLOK_00636	349741.Amuc_1286	0.0	1640.0	COG0188@1|root,COG0188@2|Bacteria,46SBE@74201|Verrucomicrobia,2ITMM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA Topoisomerase IV	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NEGHOLOK_00637	349741.Amuc_1287	2.66e-147	415.0	COG1139@1|root,COG1139@2|Bacteria	2|Bacteria	C	lactate oxidation	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NEGHOLOK_00638	349741.Amuc_1288	1.02e-296	810.0	COG0826@1|root,COG0826@2|Bacteria,46TRX@74201|Verrucomicrobia,2IVH9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Peptidase family U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32
NEGHOLOK_00639	1121101.HMPREF1532_03383	1.99e-19	87.4	COG0010@1|root,COG0010@2|Bacteria,4PHMJ@976|Bacteroidetes,2FMTD@200643|Bacteroidia,4AQ23@815|Bacteroidaceae	976|Bacteroidetes	E	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family	-	-	3.5.3.1	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00134	R00551	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NEGHOLOK_00640	349741.Amuc_1290	0.0	2415.0	COG0823@1|root,COG1262@1|root,COG0823@2|Bacteria,COG1262@2|Bacteria,46TMC@74201|Verrucomicrobia,2IVG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Involved in the tonB-independent uptake of proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00641	349741.Amuc_1291	0.0	1228.0	COG1858@1|root,COG3391@1|root,COG1858@2|Bacteria,COG3391@2|Bacteria,46X7X@74201|Verrucomicrobia,2IUXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	cytochrome C peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	CCP_MauG
NEGHOLOK_00642	349741.Amuc_1292	1.39e-281	768.0	COG0251@1|root,COG0251@2|Bacteria,46V48@74201|Verrucomicrobia	74201|Verrucomicrobia	J	PFAM Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
NEGHOLOK_00644	349741.Amuc_1302	3.97e-153	431.0	COG0704@1|root,COG0704@2|Bacteria	2|Bacteria	P	negative regulation of phosphate transmembrane transport	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NEGHOLOK_00645	349741.Amuc_1303	4.85e-185	514.0	COG1117@1|root,COG1117@2|Bacteria,46SB2@74201|Verrucomicrobia,2ITRC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NEGHOLOK_00646	349741.Amuc_1304	0.0	1127.0	COG0581@1|root,COG0581@2|Bacteria,46SBK@74201|Verrucomicrobia,2ITN9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NEGHOLOK_00647	349741.Amuc_1305	0.0	1506.0	COG4590@1|root,COG4590@2|Bacteria	2|Bacteria	P	Binding-protein-dependent transport system inner membrane component	pstC	-	-	ko:K02037,ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NEGHOLOK_00648	349741.Amuc_1306	9.14e-223	615.0	COG0226@1|root,COG0226@2|Bacteria,46SP0@74201|Verrucomicrobia,2IU59@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	PBP superfamily domain	-	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NEGHOLOK_00649	349741.Amuc_1307	4.49e-186	517.0	COG1117@1|root,COG1117@2|Bacteria,46SB2@74201|Verrucomicrobia,2ITRC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	-	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NEGHOLOK_00650	349741.Amuc_1308	4.97e-138	392.0	COG0704@1|root,COG0704@2|Bacteria,46SUX@74201|Verrucomicrobia,2IUGT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	PhoU domain	-	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NEGHOLOK_00651	349741.Amuc_1309	6.15e-234	643.0	COG2017@1|root,COG2017@2|Bacteria,46TS8@74201|Verrucomicrobia,2IU12@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Converts alpha-aldose to the beta-anomer	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NEGHOLOK_00652	349741.Amuc_1310	7.65e-101	293.0	COG3133@1|root,COG3133@2|Bacteria,46XNK@74201|Verrucomicrobia,2IW9F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycine zipper 2TM domain	-	-	-	ko:K06077	-	-	-	-	ko00000	-	-	-	Rick_17kDa_Anti
NEGHOLOK_00654	349741.Amuc_1312	0.0	1645.0	COG0612@1|root,COG0612@2|Bacteria,46S9I@74201|Verrucomicrobia,2ITJG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Insulinase (Peptidase family M16)	-	-	-	ko:K07263	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M16,Peptidase_M16_C
NEGHOLOK_00655	349741.Amuc_1313	4.72e-153	429.0	COG1713@1|root,COG1713@2|Bacteria	2|Bacteria	H	HD superfamily hydrolase involved in NAD metabolism	-	-	-	-	-	-	-	-	-	-	-	-	HD,HDOD
NEGHOLOK_00656	397290.C810_01647	2.74e-95	282.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,24B0N@186801|Clostridia,27KYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Maltose acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2,Mac
NEGHOLOK_00657	349741.Amuc_1314	5.03e-229	630.0	COG1533@1|root,COG1533@2|Bacteria,46S99@74201|Verrucomicrobia,2ITTT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NEGHOLOK_00658	349741.Amuc_1315	4.31e-231	634.0	COG0052@1|root,COG0052@2|Bacteria	2|Bacteria	J	Belongs to the universal ribosomal protein uS2 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
NEGHOLOK_00659	349741.Amuc_1316	1.7e-101	294.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NEGHOLOK_00660	349741.Amuc_1317	9.17e-70	210.0	COG1664@1|root,COG1664@2|Bacteria,46X69@74201|Verrucomicrobia,2IUN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
NEGHOLOK_00661	349741.Amuc_1318	2.53e-120	345.0	COG0233@1|root,COG0233@2|Bacteria,46V49@74201|Verrucomicrobia,2IUA0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NEGHOLOK_00662	349741.Amuc_1319	4.62e-165	462.0	COG0528@1|root,COG0528@2|Bacteria,46S4W@74201|Verrucomicrobia,2ITVK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Amino acid kinase family	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NEGHOLOK_00663	349741.Amuc_1320	2.94e-208	576.0	COG0668@1|root,COG0668@2|Bacteria,46V1Y@74201|Verrucomicrobia,2IUI5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mechanosensitive ion channel	-	-	-	-	-	-	-	-	-	-	-	-	MS_channel,TM_helix
NEGHOLOK_00664	349741.Amuc_1321	3.6e-152	427.0	COG0450@1|root,COG0450@2|Bacteria,46TAE@74201|Verrucomicrobia,2ITGT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal domain of 1-Cys peroxiredoxin	-	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
NEGHOLOK_00665	349741.Amuc_1322	0.0	1108.0	COG0733@1|root,COG0733@2|Bacteria,46XCF@74201|Verrucomicrobia,2IVFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:neurotransmitter symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SNF
NEGHOLOK_00666	349741.Amuc_1323	0.0	1010.0	2AEXX@1|root,314VS@2|Bacteria,46YXW@74201|Verrucomicrobia,2IUHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00667	349741.Amuc_1324	2.37e-46	149.0	COG0361@1|root,COG0361@2|Bacteria	349741.Amuc_1324|-	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00668	349741.Amuc_1325	3.08e-146	411.0	COG0353@1|root,COG0353@2|Bacteria,46SU3@74201|Verrucomicrobia,2IU9C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecR,Toprim_4
NEGHOLOK_00670	349741.Amuc_1327	3.9e-306	833.0	COG0304@1|root,COG0304@2|Bacteria,46SBU@74201|Verrucomicrobia,2ITS2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NEGHOLOK_00672	349741.Amuc_1329	4.86e-110	317.0	COG0229@1|root,COG0229@2|Bacteria	2|Bacteria	O	peptide-methionine (R)-S-oxide reductase activity	msrB	-	1.8.4.11,1.8.4.12	ko:K07305,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
NEGHOLOK_00673	349741.Amuc_1330	7.19e-260	712.0	COG0389@1|root,COG0389@2|Bacteria,46SNK@74201|Verrucomicrobia,2ITT1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NEGHOLOK_00674	349741.Amuc_1331	1.16e-301	824.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	nupG	GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009987,GO:0015211,GO:0015212,GO:0015213,GO:0015214,GO:0015553,GO:0015858,GO:0015860,GO:0015861,GO:0015862,GO:0015863,GO:0015864,GO:0015893,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032238,GO:0034641,GO:0042221,GO:0042493,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072530,GO:0072531,GO:1901264,GO:1901360,GO:1901505,GO:1901642	-	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	M00628	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.10.1,2.A.1.10.2,2.A.1.25,2.A.12	-	iECS88_1305.ECS88_2595,iECW_1372.ECW_m2299,iEcSMS35_1347.EcSMS35_3108,iWFL_1372.ECW_m2299	Nuc_H_symport
NEGHOLOK_00677	349741.Amuc_1379	3.08e-246	678.0	COG0842@1|root,COG0842@2|Bacteria,46SWI@74201|Verrucomicrobia,2IUJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NEGHOLOK_00678	349741.Amuc_1380	1.2e-242	669.0	COG0842@1|root,COG0842@2|Bacteria,46YUH@74201|Verrucomicrobia,2IVM6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NEGHOLOK_00679	349741.Amuc_1381	0.0	1155.0	COG1131@1|root,COG1131@2|Bacteria,46SF6@74201|Verrucomicrobia,2IWKB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NEGHOLOK_00680	349741.Amuc_1382	5.59e-227	627.0	COG0845@1|root,COG0845@2|Bacteria,46VJJ@74201|Verrucomicrobia,2IUUW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K01993	-	-	-	-	ko00000	-	-	-	HlyD_D23
NEGHOLOK_00681	349741.Amuc_1383	0.0	1853.0	COG0013@1|root,COG0013@2|Bacteria,46SAY@74201|Verrucomicrobia,2ITJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NEGHOLOK_00682	349741.Amuc_1384	3.85e-194	538.0	COG1183@1|root,COG1183@2|Bacteria,46SK0@74201|Verrucomicrobia,2ITHZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NEGHOLOK_00683	349741.Amuc_1385	4.03e-120	343.0	2AW71@1|root,31N22@2|Bacteria,46X8R@74201|Verrucomicrobia,2IV10@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00684	349741.Amuc_1386	8.75e-198	548.0	COG0294@1|root,COG0294@2|Bacteria,46SSW@74201|Verrucomicrobia,2ITVR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NEGHOLOK_00685	349741.Amuc_1387	0.0	1688.0	COG4485@1|root,COG4485@2|Bacteria	2|Bacteria	M	Bacterial membrane protein, YfhO	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
NEGHOLOK_00686	349741.Amuc_1388	0.0	1154.0	COG0821@1|root,COG0821@2|Bacteria,46SEF@74201|Verrucomicrobia,2IU3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GcpE protein	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
NEGHOLOK_00687	349741.Amuc_1389	9.4e-148	416.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2IU7U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	RmlD substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NEGHOLOK_00688	349741.Amuc_1390	4.38e-286	781.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_00689	349741.Amuc_1391	0.0	879.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_7,Hydrolase_4
NEGHOLOK_00690	349741.Amuc_1392	5.11e-285	778.0	COG0304@1|root,COG0304@2|Bacteria,46YTP@74201|Verrucomicrobia,2IU8X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Beta-ketoacyl synthase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NEGHOLOK_00691	349741.Amuc_1393	4.02e-262	720.0	COG0156@1|root,COG0156@2|Bacteria,46TTU@74201|Verrucomicrobia,2ITJB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Aminotransferase class I and II	-	-	2.3.1.47	ko:K00652	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03210,R10124	RC00004,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_00696	349741.Amuc_1396	0.0	1170.0	COG0173@1|root,COG0173@2|Bacteria,46S7W@74201|Verrucomicrobia,2ITZA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NEGHOLOK_00697	349741.Amuc_1397	7.37e-311	846.0	COG0124@1|root,COG0124@2|Bacteria,46V6Q@74201|Verrucomicrobia,2IWKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Histidyl-tRNA synthetase	-	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NEGHOLOK_00698	349741.Amuc_1398	1.44e-175	489.0	COG0378@1|root,COG0378@2|Bacteria,46STP@74201|Verrucomicrobia	74201|Verrucomicrobia	KO	CobW/HypB/UreG, nucleotide-binding domain	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
NEGHOLOK_00699	349741.Amuc_1399	0.0	1479.0	COG0068@1|root,COG0068@2|Bacteria,46S89@74201|Verrucomicrobia,2IVG5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	HypF finger	-	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
NEGHOLOK_00700	349741.Amuc_1400	2.74e-50	159.0	COG0298@1|root,COG0298@2|Bacteria,46T99@74201|Verrucomicrobia,2IWEC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	HupF/HypC family	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
NEGHOLOK_00701	349741.Amuc_1401	3.17e-261	715.0	COG0409@1|root,COG0409@2|Bacteria,46U5J@74201|Verrucomicrobia,2IV2C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hydrogenase formation hypA family	-	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
NEGHOLOK_00702	349741.Amuc_1402	1.71e-239	659.0	COG0309@1|root,COG0309@2|Bacteria,46U2H@74201|Verrucomicrobia,2IVJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	AIR synthase related protein, N-terminal domain	-	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NEGHOLOK_00703	349741.Amuc_1404	4.65e-279	761.0	COG0790@1|root,COG0790@2|Bacteria,46ZHX@74201|Verrucomicrobia,2IUWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
NEGHOLOK_00704	349741.Amuc_1405	0.0	1315.0	COG0438@1|root,COG2908@1|root,COG0438@2|Bacteria,COG2908@2|Bacteria,46USQ@74201|Verrucomicrobia,2ITPS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Metallophos
NEGHOLOK_00705	349741.Amuc_1406	0.0	1212.0	COG0443@1|root,COG0443@2|Bacteria,46SDM@74201|Verrucomicrobia,2ITH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	MreB/Mbl protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NEGHOLOK_00706	349741.Amuc_1407	2.2e-61	188.0	COG0234@1|root,COG0234@2|Bacteria,46SZ8@74201|Verrucomicrobia,2IUHU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NEGHOLOK_00707	349741.Amuc_1408	0.0	1015.0	COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NEGHOLOK_00708	349741.Amuc_1409	5.31e-99	288.0	COG3212@1|root,COG3212@2|Bacteria,46WQF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
NEGHOLOK_00709	349741.Amuc_1410	0.0	1375.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
NEGHOLOK_00713	349741.Amuc_1412	8.04e-298	811.0	2BUZ4@1|root,32QBJ@2|Bacteria,46WND@74201|Verrucomicrobia,2IUIR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BBP2_2
NEGHOLOK_00714	349741.Amuc_1413	0.0	1372.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46SBB@74201|Verrucomicrobia,2ITWV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
NEGHOLOK_00715	349741.Amuc_1414	3.37e-133	378.0	COG1596@1|root,COG1596@2|Bacteria,46T6Q@74201|Verrucomicrobia,2IUUF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polysaccharide biosynthesis/export protein	-	-	-	-	-	-	-	-	-	-	-	-	Poly_export,SLBB
NEGHOLOK_00717	349741.Amuc_1416	1.09e-148	419.0	COG0632@1|root,COG0632@2|Bacteria,46SZF@74201|Verrucomicrobia,2IUHG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NEGHOLOK_00718	349741.Amuc_1417	1.67e-249	684.0	COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,2ITXT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain	-	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
NEGHOLOK_00719	349741.Amuc_1418	1.36e-284	778.0	COG0126@1|root,COG0126@2|Bacteria,46SI9@74201|Verrucomicrobia,2ITXY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglycerate kinase	pgk	-	2.7.2.3	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01512	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
NEGHOLOK_00720	349741.Amuc_1419	2.58e-234	645.0	28I0W@1|root,30QX6@2|Bacteria,46WYN@74201|Verrucomicrobia,2IUKF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00721	349741.Amuc_1420	0.0	1304.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	GH97_C,GH97_N,Glyco_hydro_97
NEGHOLOK_00722	349741.Amuc_1421	0.0	1686.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
NEGHOLOK_00723	1123070.KB899252_gene912	0.0	1120.0	COG1197@1|root,COG1197@2|Bacteria,46S6Y@74201|Verrucomicrobia,2ITM9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TRCF	-	-	-	-	-	-	-	-	-	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NEGHOLOK_00724	349741.Amuc_1423	3.12e-294	802.0	2EZMG@1|root,33SSM@2|Bacteria,46UUT@74201|Verrucomicrobia,2IU6Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00725	349741.Amuc_1424	0.0	1592.0	COG2271@1|root,COG3055@1|root,COG2271@2|Bacteria,COG3055@2|Bacteria,46SJ9@74201|Verrucomicrobia,2IU79@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NEGHOLOK_00726	349741.Amuc_1425	1e-252	691.0	COG3055@1|root,COG3055@2|Bacteria,46T14@74201|Verrucomicrobia,2IUGH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00728	349741.Amuc_1427	5.56e-214	588.0	COG1387@1|root,COG1387@2|Bacteria,46SMB@74201|Verrucomicrobia,2IU6X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PHP domain	-	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NEGHOLOK_00729	349741.Amuc_1428	1.63e-258	709.0	COG0280@1|root,COG0280@2|Bacteria,46SP5@74201|Verrucomicrobia,2IU3X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NEGHOLOK_00730	349741.Amuc_1429	4.05e-242	665.0	COG0037@1|root,COG0037@2|Bacteria,46T0B@74201|Verrucomicrobia,2IUJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS
NEGHOLOK_00731	349741.Amuc_1430	2.59e-75	224.0	COG0254@1|root,COG0254@2|Bacteria,46T4W@74201|Verrucomicrobia,2IUJ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L31	-	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NEGHOLOK_00735	349741.Amuc_1432	1.89e-100	291.0	COG3015@1|root,COG3015@2|Bacteria	2|Bacteria	MP	regulation of cell-substrate adhesion	-	-	-	-	-	-	-	-	-	-	-	-	NlpE
NEGHOLOK_00739	349741.Amuc_1435	9.45e-317	862.0	COG1004@1|root,COG1004@2|Bacteria,46S6E@74201|Verrucomicrobia,2IU1R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
NEGHOLOK_00740	349741.Amuc_1436	1.83e-231	637.0	COG0039@1|root,COG0039@2|Bacteria,46SC4@74201|Verrucomicrobia,2ITGY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible oxidation of malate to oxaloacetate	-	-	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
NEGHOLOK_00741	349741.Amuc_1437	0.0	1475.0	COG3408@1|root,COG3408@2|Bacteria	2|Bacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid6H,DUF608,GDE_C
NEGHOLOK_00742	349741.Amuc_1438	0.0	1290.0	2DTCE@1|root,32UUZ@2|Bacteria,46Z6Q@74201|Verrucomicrobia,2IWPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NPCBM/NEW2 domain	-	-	-	-	-	-	-	-	-	-	-	-	NPCBM
NEGHOLOK_00743	349741.Amuc_1439	0.0	1636.0	COG1452@1|root,COG1452@2|Bacteria,46SJX@74201|Verrucomicrobia,2ITQV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane	-	-	-	ko:K04744	-	-	-	-	ko00000,ko02000	1.B.42.1	-	-	-
NEGHOLOK_00744	349741.Amuc_1440	1.51e-152	428.0	COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
NEGHOLOK_00745	349741.Amuc_1441	1.07e-192	533.0	COG0564@1|root,COG0564@2|Bacteria,46V2B@74201|Verrucomicrobia,2IU67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NEGHOLOK_00746	349741.Amuc_1442	3.17e-171	477.0	COG1187@1|root,COG1187@2|Bacteria,46V36@74201|Verrucomicrobia,2IUHB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NEGHOLOK_00747	349741.Amuc_1443	0.0	876.0	COG0457@1|root,COG0457@2|Bacteria,46TQ7@74201|Verrucomicrobia,2ITH6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NEGHOLOK_00748	349741.Amuc_1444	4.37e-124	353.0	COG0563@1|root,COG0563@2|Bacteria	2|Bacteria	F	adenylate kinase activity	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AAA_18,ADK
NEGHOLOK_00749	349741.Amuc_1445	1.77e-166	466.0	COG1126@1|root,COG1126@2|Bacteria,46UVK@74201|Verrucomicrobia,2IUC5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NEGHOLOK_00750	349741.Amuc_1446	0.0	935.0	COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,46TJR@74201|Verrucomicrobia,2IU6P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NEGHOLOK_00752	349741.Amuc_1447	1.44e-253	695.0	COG0002@1|root,COG0002@2|Bacteria,46SA3@74201|Verrucomicrobia,2IU18@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Semialdehyde dehydrogenase, NAD binding domain	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NEGHOLOK_00753	349741.Amuc_1448	2.26e-306	834.0	COG1364@1|root,COG1364@2|Bacteria,46SEP@74201|Verrucomicrobia,2ITT9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NEGHOLOK_00754	349741.Amuc_1449	3.39e-109	314.0	COG0727@1|root,COG0727@2|Bacteria,46VKZ@74201|Verrucomicrobia,2IUMM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc- or iron-chelating domain	-	-	-	-	-	-	-	-	-	-	-	-	CxxCxxCC
NEGHOLOK_00755	349741.Amuc_1450	7.7e-31	128.0	COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia,2IUT4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
NEGHOLOK_00757	349741.Amuc_1452	0.0	1628.0	COG0178@1|root,COG0178@2|Bacteria,46SEB@74201|Verrucomicrobia,2ITPE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	ATPases associated with a variety of cellular activities	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NEGHOLOK_00758	349741.Amuc_1453	2.41e-148	417.0	COG1664@1|root,COG1664@2|Bacteria,46WDW@74201|Verrucomicrobia,2IW9H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
NEGHOLOK_00759	349741.Amuc_1454	1.14e-126	362.0	COG1664@1|root,COG1664@2|Bacteria,46VS6@74201|Verrucomicrobia,2IUPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Polymer-forming cytoskeletal	-	-	-	-	-	-	-	-	-	-	-	-	Bactofilin
NEGHOLOK_00760	349741.Amuc_1455	7.06e-249	682.0	2A0NC@1|root,30NSM@2|Bacteria,46XRM@74201|Verrucomicrobia,2IWFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00762	349741.Amuc_1457	4.5e-176	491.0	COG0106@1|root,COG0106@2|Bacteria,46U39@74201|Verrucomicrobia,2ITHN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Histidine biosynthesis protein	-	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NEGHOLOK_00763	349741.Amuc_1458	3.65e-60	185.0	COG1872@1|root,COG1872@2|Bacteria,46T9T@74201|Verrucomicrobia,2IUWZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DUF167	-	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
NEGHOLOK_00764	349741.Amuc_1459	1.16e-114	330.0	COG0576@1|root,COG0576@2|Bacteria,46T79@74201|Verrucomicrobia,2IUHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NEGHOLOK_00765	349741.Amuc_1460	1.2e-262	721.0	COG0484@1|root,COG0484@2|Bacteria,46TKC@74201|Verrucomicrobia,2ITUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NEGHOLOK_00766	349741.Amuc_1461	1.34e-175	489.0	COG1385@1|root,COG1385@2|Bacteria,46SZQ@74201|Verrucomicrobia,2IUB0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NEGHOLOK_00767	349741.Amuc_1462	2.96e-242	665.0	COG0546@1|root,COG1539@1|root,COG0546@2|Bacteria,COG1539@2|Bacteria,46VY5@74201|Verrucomicrobia,2IUEQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2,NUDIX
NEGHOLOK_00768	349741.Amuc_1463	0.0	1233.0	COG5434@1|root,COG5434@2|Bacteria,46X9H@74201|Verrucomicrobia,2IV3W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00769	349741.Amuc_1464	1.02e-228	629.0	COG1562@1|root,COG1562@2|Bacteria,46TVP@74201|Verrucomicrobia,2IU9Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Squalene/phytoene synthase	-	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
NEGHOLOK_00770	349741.Amuc_1465	0.0	873.0	COG0681@1|root,COG0681@2|Bacteria,46SR0@74201|Verrucomicrobia,2IU66@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Peptidase S24-like	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
NEGHOLOK_00771	349741.Amuc_1466	0.0	915.0	COG0277@1|root,COG0277@2|Bacteria,46SFA@74201|Verrucomicrobia,2ITGW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
NEGHOLOK_00772	349741.Amuc_1467	6.29e-151	422.0	2B2BG@1|root,31UVN@2|Bacteria,46ZHA@74201|Verrucomicrobia,2IUTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00773	349741.Amuc_1468	5.95e-167	465.0	COG3319@1|root,COG3319@2|Bacteria	2|Bacteria	Q	amino acid activation for nonribosomal peptide biosynthetic process	pks6	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,Thioesterase,ketoacyl-synt
NEGHOLOK_00774	349741.Amuc_1469	1.76e-173	483.0	2DKIU@1|root,309MI@2|Bacteria,46W7D@74201|Verrucomicrobia,2IUZM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3485)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3485
NEGHOLOK_00775	349741.Amuc_1470	1.19e-229	632.0	COG1269@1|root,COG1269@2|Bacteria,46VW2@74201|Verrucomicrobia,2IWJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transmembrane exosortase (Exosortase_EpsH)	-	-	-	-	-	-	-	-	-	-	-	-	Exosortase_EpsH
NEGHOLOK_00776	349741.Amuc_1471	4.58e-220	608.0	COG0462@1|root,COG0462@2|Bacteria,46SVH@74201|Verrucomicrobia,2ITT3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
NEGHOLOK_00777	349741.Amuc_1472	1.51e-132	377.0	COG1825@1|root,COG1825@2|Bacteria,46SZS@74201|Verrucomicrobia,2IUP1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NEGHOLOK_00779	349741.Amuc_1474	1.48e-141	399.0	COG0131@1|root,COG0131@2|Bacteria,46SR2@74201|Verrucomicrobia,2IU4M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Imidazoleglycerol-phosphate dehydratase	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NEGHOLOK_00780	349741.Amuc_1475	6.22e-146	410.0	COG0118@1|root,COG0118@2|Bacteria,46V4G@74201|Verrucomicrobia,2IUAC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NEGHOLOK_00781	349741.Amuc_1476	6.37e-60	184.0	COG0360@1|root,COG0360@2|Bacteria,46TBG@74201|Verrucomicrobia,2IUU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S6	-	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
NEGHOLOK_00782	349741.Amuc_1477	4.4e-212	585.0	COG1995@1|root,COG1995@2|Bacteria,46SNQ@74201|Verrucomicrobia,2ITTC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Pyridoxal phosphate biosynthetic protein PdxA	-	-	1.1.1.262	ko:K00097	ko00750,ko01100,map00750,map01100	M00124	R05681,R05837,R07406	RC00089,RC00675,RC01475	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxA
NEGHOLOK_00785	349741.Amuc_1480	3.37e-224	619.0	COG1686@1|root,COG1686@2|Bacteria,46VPH@74201|Verrucomicrobia,2IU96@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
NEGHOLOK_00786	349741.Amuc_1481	9e-254	696.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2ITQA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphofructokinase	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NEGHOLOK_00787	349741.Amuc_1482	4.82e-220	610.0	COG3152@1|root,COG3152@2|Bacteria	2|Bacteria	L	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF805
NEGHOLOK_00788	349741.Amuc_1483	1.52e-173	486.0	COG0428@1|root,COG0428@2|Bacteria	2|Bacteria	P	transporter	zupT	GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	iECIAI39_1322.ECIAI39_3536	Zip
NEGHOLOK_00789	349741.Amuc_1484	9.1e-237	652.0	COG0526@1|root,COG0526@2|Bacteria,46SXQ@74201|Verrucomicrobia,2IWPU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Protein of unknown function, DUF255	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2
NEGHOLOK_00792	349741.Amuc_1487	0.0	882.0	COG3977@1|root,COG3977@2|Bacteria,46YY9@74201|Verrucomicrobia,2ITU5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.66	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	-	R01215	RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_00793	349741.Amuc_1488	4.1e-193	537.0	COG1561@1|root,COG1561@2|Bacteria,46TP9@74201|Verrucomicrobia,2IU44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1732)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NEGHOLOK_00794	349741.Amuc_1489	4.39e-145	408.0	COG0194@1|root,COG0194@2|Bacteria,46SQG@74201|Verrucomicrobia,2IU9Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Guanylate kinase homologues.	-	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NEGHOLOK_00795	349741.Amuc_1490	0.0	1214.0	COG0471@1|root,COG0569@1|root,COG3273@1|root,COG0471@2|Bacteria,COG0569@2|Bacteria,COG3273@2|Bacteria,46TTA@74201|Verrucomicrobia,2IU1V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,TrkA_C
NEGHOLOK_00796	349741.Amuc_1491	7.58e-209	576.0	COG0008@1|root,COG0008@2|Bacteria,46SQ3@74201|Verrucomicrobia,2ITGN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (E and Q), catalytic domain	-	-	-	ko:K01894	-	-	-	-	ko00000,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c
NEGHOLOK_00799	349741.Amuc_1494	3.1e-217	600.0	COG1575@1|root,COG1575@2|Bacteria,46V9A@74201|Verrucomicrobia,2IU5W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	UbiA prenyltransferase family	menA	-	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
NEGHOLOK_00800	349741.Amuc_1495	4.49e-169	472.0	COG0710@1|root,COG0710@2|Bacteria,46VMG@74201|Verrucomicrobia,2IUIA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Type I 3-dehydroquinase	-	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I
NEGHOLOK_00802	349741.Amuc_1497	1.12e-217	602.0	2BDDY@1|root,32730@2|Bacteria,46WKY@74201|Verrucomicrobia,2IWBU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00803	349741.Amuc_1498	3.17e-166	464.0	COG1496@1|root,COG1496@2|Bacteria,46STZ@74201|Verrucomicrobia,2IUDE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Multi-copper polyphenol oxidoreductase laccase	-	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NEGHOLOK_00804	349741.Amuc_1499	1.28e-172	481.0	COG3026@1|root,COG3026@2|Bacteria,46W95@74201|Verrucomicrobia,2IUUR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Outer membrane lipoprotein-sorting protein	-	-	-	-	-	-	-	-	-	-	-	-	LolA_like
NEGHOLOK_00805	349741.Amuc_1500	9.72e-227	625.0	COG0726@1|root,COG0726@2|Bacteria,46UKH@74201|Verrucomicrobia,2IU6W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NEGHOLOK_00806	349741.Amuc_1501	0.0	1507.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,46SA4@74201|Verrucomicrobia,2ITYV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4	-	-	SecD_SecF,Sec_GG
NEGHOLOK_00808	349741.Amuc_1503	3.26e-278	759.0	COG1989@1|root,COG1989@2|Bacteria,46TWT@74201|Verrucomicrobia,2IU6Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NOU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
NEGHOLOK_00809	349741.Amuc_1504	1.38e-257	706.0	COG1611@1|root,COG1611@2|Bacteria,46SEG@74201|Verrucomicrobia,2ITGC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
NEGHOLOK_00810	349741.Amuc_1505	2.95e-262	719.0	COG0202@1|root,COG0202@2|Bacteria,46S52@74201|Verrucomicrobia,2ITN6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NEGHOLOK_00811	349741.Amuc_1506	4.19e-87	256.0	COG0203@1|root,COG0203@2|Bacteria,46TC9@74201|Verrucomicrobia,2IUE5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NEGHOLOK_00812	349741.Amuc_1507	1.54e-217	600.0	COG0331@1|root,COG0331@2|Bacteria,46SNS@74201|Verrucomicrobia,2ITTM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NEGHOLOK_00814	349741.Amuc_1509	6.65e-169	471.0	COG0637@1|root,COG0637@2|Bacteria,46W9J@74201|Verrucomicrobia,2IUD3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NEGHOLOK_00815	349741.Amuc_1510	3.06e-286	785.0	COG0795@1|root,COG0795@2|Bacteria,46T0M@74201|Verrucomicrobia,2IU8Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Predicted permease YjgP/YjgQ family	-	-	-	ko:K11720	ko02010,map02010	M00320	-	-	ko00000,ko00001,ko00002,ko02000	1.B.42.1	-	-	YjgP_YjgQ
NEGHOLOK_00816	349741.Amuc_1511	3.63e-270	739.0	COG1506@1|root,COG1506@2|Bacteria	2|Bacteria	E	serine-type peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,DUF2048,Peptidase_S9
NEGHOLOK_00817	349741.Amuc_1512	1.85e-304	835.0	COG2885@1|root,COG2885@2|Bacteria,46T6J@74201|Verrucomicrobia,2IUNT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
NEGHOLOK_00818	349741.Amuc_1513	7.32e-215	592.0	COG0561@1|root,COG0561@2|Bacteria,46SWT@74201|Verrucomicrobia,2IUQM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NEGHOLOK_00819	349741.Amuc_1514	0.0	1177.0	COG3064@1|root,COG3064@2|Bacteria,46TMJ@74201|Verrucomicrobia,2IVP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase M60-like family	-	-	-	-	-	-	-	-	-	-	-	-	M60-like_N,Peptidase_M60
NEGHOLOK_00820	349741.Amuc_1515	9.77e-296	807.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
NEGHOLOK_00821	349741.Amuc_1516	0.0	1090.0	COG2202@1|root,COG2208@1|root,COG2202@2|Bacteria,COG2208@2|Bacteria,46U96@74201|Verrucomicrobia,2ITU0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	PAS_3,PAS_4,SpoIIE
NEGHOLOK_00822	349741.Amuc_1517	6.91e-165	461.0	COG1595@1|root,COG1595@2|Bacteria,46VJP@74201|Verrucomicrobia,2IU42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
NEGHOLOK_00823	349741.Amuc_1518	1.16e-242	666.0	COG3568@1|root,COG3568@2|Bacteria,46Z38@74201|Verrucomicrobia,2IUCM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
NEGHOLOK_00824	349741.Amuc_1523	3.26e-173	483.0	COG4970@1|root,COG4970@2|Bacteria	2|Bacteria	NU	protein transport across the cell outer membrane	-	-	-	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15,3.A.15.2	-	-	GspH,N_methyl
NEGHOLOK_00825	349741.Amuc_1524	9.06e-189	524.0	2AW2C@1|root,31MX3@2|Bacteria,46X74@74201|Verrucomicrobia,2IUTK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_00826	349741.Amuc_1525	7.31e-247	679.0	COG4966@1|root,COG4966@2|Bacteria,46WRK@74201|Verrucomicrobia,2IUK5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_00827	349741.Amuc_1526	6.92e-183	508.0	COG0095@1|root,COG0095@2|Bacteria,46T01@74201|Verrucomicrobia,2IUII@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.1.20	ko:K03800	ko00785,ko01100,map00785,map01100	-	R07770,R07771,R11143	RC00043,RC00070,RC00090,RC00992,RC02896	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB
NEGHOLOK_00828	349741.Amuc_1527	4.06e-244	669.0	COG0667@1|root,COG0667@2|Bacteria,46U3T@74201|Verrucomicrobia,2ITTY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
NEGHOLOK_00829	349741.Amuc_1528	0.0	1391.0	COG3808@1|root,COG3808@2|Bacteria,46S7R@74201|Verrucomicrobia,2ITQY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
NEGHOLOK_00833	349741.Amuc_1531	0.0	917.0	COG0147@1|root,COG0147@2|Bacteria,46S4I@74201|Verrucomicrobia,2ITH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Anthranilate synthase component I, N terminal region	-	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NEGHOLOK_00834	349741.Amuc_1532	0.0	1058.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,46SQA@74201|Verrucomicrobia,2ITKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
NEGHOLOK_00835	349741.Amuc_1533	1.67e-177	495.0	COG0134@1|root,COG0134@2|Bacteria,46V9B@74201|Verrucomicrobia,2ITZZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Indole-3-glycerol phosphate synthase	-	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NEGHOLOK_00836	349741.Amuc_1534	2.94e-155	435.0	COG0135@1|root,COG0135@2|Bacteria,46VS4@74201|Verrucomicrobia,2IUJV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NEGHOLOK_00837	349741.Amuc_1535	3.6e-287	783.0	COG0133@1|root,COG0133@2|Bacteria,46SHR@74201|Verrucomicrobia,2ITRB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NEGHOLOK_00838	349741.Amuc_1536	5.46e-188	522.0	COG0159@1|root,COG0159@2|Bacteria,46SK1@74201|Verrucomicrobia,2ITJI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
NEGHOLOK_00840	349741.Amuc_1537	0.0	5472.0	COG2911@1|root,COG4625@1|root,COG2911@2|Bacteria,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,ESPR,Haemagg_act,PATR
NEGHOLOK_00841	349741.Amuc_1538	6.2e-89	261.0	COG1764@1|root,COG1764@2|Bacteria	2|Bacteria	O	response to oxidative stress	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
NEGHOLOK_00843	880070.Cycma_4169	5.79e-31	122.0	COG2755@1|root,COG2755@2|Bacteria,4PAI3@976|Bacteroidetes,47TQE@768503|Cytophagia	976|Bacteroidetes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_00844	1410624.JNKK01000013_gene1495	3.97e-07	52.8	COG0491@1|root,COG0491@2|Bacteria,1UZUA@1239|Firmicutes,24CIA@186801|Clostridia,27QHY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NEGHOLOK_00847	349741.Amuc_1539	4.15e-287	783.0	COG2021@1|root,COG2021@2|Bacteria,46U58@74201|Verrucomicrobia,2ITGZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	alpha/beta hydrolase fold	-	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
NEGHOLOK_00848	349741.Amuc_1540	1.08e-63	196.0	COG0257@1|root,COG0257@2|Bacteria,46TAZ@74201|Verrucomicrobia,2IUUV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L36	-	-	-	ko:K02919	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L36
NEGHOLOK_00849	349741.Amuc_1541	0.0	1223.0	COG0859@1|root,COG1560@1|root,COG0859@2|Bacteria,COG1560@2|Bacteria,46SSR@74201|Verrucomicrobia,2IUNU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyltransferase family 9 (heptosyltransferase)	-	-	2.3.1.241	ko:K02517	ko00540,ko01100,map00540,map01100	M00060	R05146	RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Glyco_transf_9,Lip_A_acyltrans
NEGHOLOK_00850	349741.Amuc_1542	1.35e-191	531.0	COG1180@1|root,COG1180@2|Bacteria,46YX6@74201|Verrucomicrobia,2IVDY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NEGHOLOK_00851	349741.Amuc_1543	0.0	1500.0	COG1882@1|root,COG1882@2|Bacteria,46XB7@74201|Verrucomicrobia,2IV9D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Pyruvate formate lyase-like	-	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NEGHOLOK_00852	349741.Amuc_1544	8.08e-189	524.0	COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_00853	349741.Amuc_1546	5.24e-186	517.0	COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_00854	349741.Amuc_1547	0.0	1228.0	COG4409@1|root,COG4409@2|Bacteria,46WSQ@74201|Verrucomicrobia,2IWA2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2,Lipase_GDSL_2
NEGHOLOK_00855	349741.Amuc_1548	0.0	910.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	legA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Ank_2,Ank_4,Peptidase_M48
NEGHOLOK_00856	349741.Amuc_1549	3.79e-195	542.0	COG0561@1|root,COG0561@2|Bacteria	2|Bacteria	Q	phosphatase activity	supH	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NEGHOLOK_00858	349741.Amuc_1551	5.49e-85	250.0	COG0838@1|root,COG0838@2|Bacteria,46T33@74201|Verrucomicrobia,2IUK0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
NEGHOLOK_00859	349741.Amuc_1552	4.12e-275	753.0	COG0738@1|root,COG0738@2|Bacteria,46Z6R@74201|Verrucomicrobia,2IWPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NEGHOLOK_00860	665577.JH993790_gene5822	2.78e-05	55.5	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NEGHOLOK_00862	1282361.ABAC402_18760	6e-37	127.0	COG1396@1|root,COG1396@2|Bacteria,1N8D1@1224|Proteobacteria,2UHRM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
NEGHOLOK_00863	658187.LDG_6000	3.04e-167	482.0	COG3550@1|root,COG3550@2|Bacteria,1N458@1224|Proteobacteria,1RNYG@1236|Gammaproteobacteria,1JFTD@118969|Legionellales	118969|Legionellales	S	Pfam:HipA_N	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HipA_C
NEGHOLOK_00864	195250.CM001776_gene794	4.84e-36	132.0	COG4185@1|root,COG4185@2|Bacteria,1G56J@1117|Cyanobacteria	1117|Cyanobacteria	S	zeta toxin	-	-	-	-	-	-	-	-	-	-	-	-	Zeta_toxin
NEGHOLOK_00871	398578.Daci_4158	3.73e-45	160.0	COG1961@1|root,COG1961@2|Bacteria,1QTU0@1224|Proteobacteria,2VITE@28216|Betaproteobacteria,4AD9E@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF932)	-	-	-	-	-	-	-	-	-	-	-	-	DUF932
NEGHOLOK_00873	999413.HMPREF1094_00569	0.0	1488.0	COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,3VP89@526524|Erysipelotrichia	526524|Erysipelotrichia	V	Subunit R is required for both nuclease and ATPase activities, but not for modification	hsdR	-	-	-	-	-	-	-	-	-	-	-	EcoR124_C,HSDR_N,ResIII
NEGHOLOK_00874	1035193.HMPREF9073_00600	5.66e-27	111.0	COG1846@1|root,COG2184@1|root,COG1846@2|Bacteria,COG2184@2|Bacteria,4NGIN@976|Bacteroidetes,1IEV0@117743|Flavobacteriia,1ER7G@1016|Capnocytophaga	976|Bacteroidetes	DK	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
NEGHOLOK_00875	1214217.ALNF01000046_gene1908	8e-101	312.0	COG0732@1|root,COG0732@2|Bacteria,1UXUT@1239|Firmicutes,4I4FD@91061|Bacilli,1WTQ5@1307|Streptococcus suis	91061|Bacilli	L	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NEGHOLOK_00876	349741.Amuc_1915	0.0	1226.0	COG0286@1|root,COG1382@1|root,COG0286@2|Bacteria,COG1382@2|Bacteria,46UA6@74201|Verrucomicrobia,2IU5D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	N-6 DNA Methylase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,N6_Mtase
NEGHOLOK_00877	1121439.dsat_2749	2.63e-101	308.0	COG1715@1|root,COG1715@2|Bacteria,1R4NQ@1224|Proteobacteria,43B1F@68525|delta/epsilon subdivisions,2X6FN@28221|Deltaproteobacteria,2MH2I@213115|Desulfovibrionales	28221|Deltaproteobacteria	L	HB1, ASXL, restriction endonuclease HTH domain	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	HARE-HTH,Mrr_cat
NEGHOLOK_00878	1396141.BATP01000001_gene5375	1.58e-92	282.0	COG2887@1|root,COG2887@2|Bacteria,46VRY@74201|Verrucomicrobia,2IVVM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
NEGHOLOK_00879	1396141.BATP01000001_gene5376	5.53e-40	142.0	2FDAI@1|root,345CE@2|Bacteria,46WE8@74201|Verrucomicrobia,2IVX3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00882	981336.F944_01339	7.55e-05	49.7	COG2314@1|root,COG2314@2|Bacteria,1RJJN@1224|Proteobacteria,1S6WP@1236|Gammaproteobacteria,3NQ4Z@468|Moraxellaceae	1236|Gammaproteobacteria	S	TM2 domain	-	-	-	-	-	-	-	-	-	-	-	-	Pilin,TM2
NEGHOLOK_00889	349741.Amuc_0080	1.07e-58	223.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
NEGHOLOK_00890	690850.Desaf_3455	7.44e-125	370.0	COG3943@1|root,COG3943@2|Bacteria,1MWKW@1224|Proteobacteria,42MTT@68525|delta/epsilon subdivisions,2WM31@28221|Deltaproteobacteria,2M9SW@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
NEGHOLOK_00891	644282.Deba_2533	1.29e-161	466.0	COG3177@1|root,COG3398@1|root,COG3177@2|Bacteria,COG3398@2|Bacteria,1MV69@1224|Proteobacteria,42MWV@68525|delta/epsilon subdivisions,2WJJZ@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	filamentation induced by cAMP protein Fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,Fic_N,HTH_24
NEGHOLOK_00892	1144313.PMI10_01059	9.51e-27	114.0	COG1715@1|root,COG1715@2|Bacteria,4PCT8@976|Bacteroidetes,1IDBA@117743|Flavobacteriia,2NXXZ@237|Flavobacterium	976|Bacteroidetes	V	Restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00893	411471.SUBVAR_07192	6.29e-41	147.0	COG4245@1|root,COG4245@2|Bacteria,1UYN8@1239|Firmicutes,24PQD@186801|Clostridia,3WM02@541000|Ruminococcaceae	186801|Clostridia	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA
NEGHOLOK_00894	649831.L083_0250	1.53e-07	62.4	COG0515@1|root,COG0515@2|Bacteria,2GMRN@201174|Actinobacteria,4D9NR@85008|Micromonosporales	201174|Actinobacteria	KLT	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	LANC_like,Pkinase
NEGHOLOK_00895	349741.Amuc_2055	6.22e-74	221.0	COG1633@1|root,COG1633@2|Bacteria	2|Bacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	COQ7,Rubrerythrin
NEGHOLOK_00896	349741.Amuc_2054	1.58e-117	336.0	COG1433@1|root,COG1433@2|Bacteria	2|Bacteria	S	nitrogen fixation	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NEGHOLOK_00897	349741.Amuc_2053	1.58e-148	419.0	COG0586@1|root,COG0586@2|Bacteria	2|Bacteria	S	FtsZ-dependent cytokinesis	dedA	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
NEGHOLOK_00898	349741.Amuc_2052	2.36e-269	737.0	COG0763@1|root,COG0763@2|Bacteria,46SSG@74201|Verrucomicrobia,2ITSK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.4.1.182	ko:K00748	ko00540,ko01100,map00540,map01100	M00060	R04606	RC00005,RC00059	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT19	-	LpxB
NEGHOLOK_00899	349741.Amuc_2051	0.0	907.0	COG0334@1|root,COG0334@2|Bacteria,46YXD@74201|Verrucomicrobia,2ITNI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	1.4.1.4	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	-	R00248	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NEGHOLOK_00900	349741.Amuc_2050	7.09e-253	692.0	COG1943@1|root,COG1943@2|Bacteria,46V2P@74201|Verrucomicrobia,2IVVU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Transposase IS200 like	-	-	-	-	-	-	-	-	-	-	-	-	Y1_Tnp
NEGHOLOK_00901	349741.Amuc_2049	0.0	1126.0	COG0038@1|root,COG0517@1|root,COG0038@2|Bacteria,COG0517@2|Bacteria,46S8W@74201|Verrucomicrobia,2IU71@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Voltage gated chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
NEGHOLOK_00902	349741.Amuc_2048	1.34e-109	315.0	COG1762@1|root,COG1762@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsN	GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698	2.7.1.202	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2
NEGHOLOK_00905	349741.Amuc_2046	1.59e-150	422.0	COG4112@1|root,COG4112@2|Bacteria,46V3C@74201|Verrucomicrobia,2IU8G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00906	349741.Amuc_2045	0.0	1703.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin,Calx-beta,FG-GAP,Flg_new,Laminin_G_3,Lipase_GDSL_2,M60-like_N,PA14,Peptidase_M60
NEGHOLOK_00908	349741.Amuc_2043	0.0	907.0	COG1538@1|root,COG1538@2|Bacteria,46SFR@74201|Verrucomicrobia,2IUDN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	ko:K18139	ko01501,ko02024,map01501,map02024	M00642,M00643,M00647,M00718,M00768,M00822	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	1.B.17,2.A.6.2	-	-	OEP
NEGHOLOK_00909	349741.Amuc_2042	0.0	2011.0	COG0841@1|root,COG0841@2|Bacteria,46SDN@74201|Verrucomicrobia,2IWND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NEGHOLOK_00910	349741.Amuc_2041	2.24e-282	774.0	COG0845@1|root,COG0845@2|Bacteria,46X9T@74201|Verrucomicrobia,2IVR2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2
NEGHOLOK_00911	349741.Amuc_2040	0.0	1431.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae	2|Bacteria	E	Peptidase family M3	prlC	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
NEGHOLOK_00912	349741.Amuc_2039	0.0	1082.0	COG0119@1|root,COG0119@2|Bacteria,46S6Z@74201|Verrucomicrobia,2ITQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	LeuA allosteric (dimerisation) domain	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
NEGHOLOK_00913	349741.Amuc_2038	2.77e-41	135.0	2DFNJ@1|root,2ZSFW@2|Bacteria,46WS2@74201|Verrucomicrobia,2IUSJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	PurA ssDNA and RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	PurA
NEGHOLOK_00914	349741.Amuc_2037	2.49e-255	700.0	COG0489@1|root,COG0489@2|Bacteria,46SAV@74201|Verrucomicrobia,2ITW9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Iron-sulfur cluster assembly protein	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
NEGHOLOK_00915	349741.Amuc_2036	0.0	892.0	COG0534@1|root,COG0534@2|Bacteria,46UTM@74201|Verrucomicrobia,2IU2M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
NEGHOLOK_00916	1519439.JPJG01000064_gene1790	0.0	1203.0	COG4096@1|root,COG4096@2|Bacteria,1UIK9@1239|Firmicutes,25GRJ@186801|Clostridia	186801|Clostridia	V	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	MUG113,ResIII,T5orf172
NEGHOLOK_00917	742738.HMPREF9460_01135	2.04e-198	568.0	COG0286@1|root,COG0286@2|Bacteria,1UMXA@1239|Firmicutes	1239|Firmicutes	L	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	Eco57I
NEGHOLOK_00918	1392491.JIAE01000001_gene2187	9.13e-63	202.0	COG1002@1|root,COG1002@2|Bacteria,1TWDC@1239|Firmicutes,259SR@186801|Clostridia,3WQMA@541000|Ruminococcaceae	186801|Clostridia	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00919	349741.Amuc_2006	6.33e-74	240.0	COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NEGHOLOK_00920	349741.Amuc_2034	0.0	1008.0	COG5016@1|root,COG5016@2|Bacteria,46UNW@74201|Verrucomicrobia,2IWQ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	HMGL-like	-	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NEGHOLOK_00921	349741.Amuc_2033	0.0	971.0	COG1502@1|root,COG1502@2|Bacteria,46U9X@74201|Verrucomicrobia,2ITQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NEGHOLOK_00922	349741.Amuc_2032	5.77e-208	573.0	COG0207@1|root,COG0207@2|Bacteria,46SCY@74201|Verrucomicrobia,2ITI7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Thymidylate synthase	-	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
NEGHOLOK_00923	349741.Amuc_2031	5.02e-115	329.0	COG0262@1|root,COG0262@2|Bacteria,46T19@74201|Verrucomicrobia,2IUNY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Dihydrofolate reductase	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
NEGHOLOK_00924	349741.Amuc_2030	0.0	1953.0	COG0841@1|root,COG0841@2|Bacteria,46U0U@74201|Verrucomicrobia,2ITVP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	-	-	-	-	-	-	-	-	-	ACR_tran
NEGHOLOK_00925	349741.Amuc_2029	4.2e-264	724.0	COG0845@1|root,COG0845@2|Bacteria,46U1A@74201|Verrucomicrobia,2IV1B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2
NEGHOLOK_00926	349741.Amuc_2028	4.85e-107	308.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NEGHOLOK_00928	349741.Amuc_2027	1.53e-241	663.0	COG0418@1|root,COG0418@2|Bacteria,46TXB@74201|Verrucomicrobia,2IVIQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Amidohydrolase	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NEGHOLOK_00929	349741.Amuc_2026	8.17e-159	444.0	COG0491@1|root,COG0491@2|Bacteria,46T2E@74201|Verrucomicrobia,2IUFH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NEGHOLOK_00930	349741.Amuc_2025	1.48e-291	795.0	COG0513@1|root,COG0513@2|Bacteria,46TUA@74201|Verrucomicrobia,2ITQU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
NEGHOLOK_00931	349741.Amuc_2024	1.71e-110	318.0	COG0817@1|root,COG0817@2|Bacteria,46T3Y@74201|Verrucomicrobia,2IUA7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	-	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
NEGHOLOK_00932	349741.Amuc_2023	4.02e-121	345.0	2FKI6@1|root,34C5C@2|Bacteria,46W75@74201|Verrucomicrobia,2IUZH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00933	349741.Amuc_2022	0.0	990.0	COG2015@1|root,COG2015@2|Bacteria	2|Bacteria	Q	COG2015, Alkyl sulfatase and related hydrolases	sepA	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
NEGHOLOK_00934	349741.Amuc_2021	1.56e-113	325.0	COG1051@1|root,COG1051@2|Bacteria,46VUY@74201|Verrucomicrobia,2IUIE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
NEGHOLOK_00935	349741.Amuc_2020	2.43e-241	663.0	COG1703@1|root,COG1703@2|Bacteria,46TIM@74201|Verrucomicrobia,2IV0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
NEGHOLOK_00936	349741.Amuc_2019	0.0	1033.0	COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae	2|Bacteria	G	Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_00937	349741.Amuc_2018	2.36e-291	798.0	COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae	2|Bacteria	G	Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_00939	349741.Amuc_2017	4.27e-117	334.0	COG3600@1|root,COG3600@2|Bacteria	2|Bacteria	K	Phage-associated protein	gepA	-	-	-	-	-	-	-	-	-	-	-	DUF4065
NEGHOLOK_00940	349741.Amuc_2016	1.15e-173	486.0	COG2145@1|root,COG2145@2|Bacteria	2|Bacteria	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NEGHOLOK_00941	349741.Amuc_2015	8.4e-136	385.0	COG0352@1|root,COG0352@2|Bacteria,46T6K@74201|Verrucomicrobia	2|Bacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.3,2.7.1.49,2.7.4.7,4.1.99.17	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	M00127	R03223,R03471,R03472,R04509,R10712	RC00002,RC00017,RC00224,RC03251,RC03252,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU38290	TMP-TENI
NEGHOLOK_00942	349741.Amuc_2014	1.86e-214	593.0	COG0031@1|root,COG0031@2|Bacteria,46W12@74201|Verrucomicrobia,2IWMW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NEGHOLOK_00943	349741.Amuc_2013	2.89e-310	845.0	COG2873@1|root,COG2873@2|Bacteria,46TEJ@74201|Verrucomicrobia,2ITJ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NEGHOLOK_00944	349741.Amuc_2012	2.55e-102	296.0	COG1959@1|root,COG1959@2|Bacteria,46X6R@74201|Verrucomicrobia,2IURA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NEGHOLOK_00945	349741.Amuc_2011	1.6e-272	744.0	COG0787@1|root,COG0787@2|Bacteria,46SM1@74201|Verrucomicrobia,2IU27@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NEGHOLOK_00946	349741.Amuc_2003	2.84e-173	485.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2
NEGHOLOK_00947	349741.Amuc_2002	0.0	1187.0	COG0326@1|root,COG0326@2|Bacteria,46U76@74201|Verrucomicrobia,2IU3I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hsp90 protein	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3,HSP90
NEGHOLOK_00948	349741.Amuc_2001	0.0	1394.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5
NEGHOLOK_00949	349741.Amuc_2000	1.35e-284	777.0	COG2807@1|root,COG2807@2|Bacteria,46XKN@74201|Verrucomicrobia,2IW54@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Major Facilitator Superfamily	-	-	-	ko:K03449	-	-	-	-	ko00000,ko02000	2.A.1.17	-	-	MFS_1
NEGHOLOK_00950	349741.Amuc_1999	1.16e-240	662.0	COG0016@1|root,COG0016@2|Bacteria,46S6R@74201|Verrucomicrobia,2ITTX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Aminoacyl tRNA synthetase class II, N-terminal domain	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NEGHOLOK_00951	349741.Amuc_1998	0.0	1625.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,46SDG@74201|Verrucomicrobia,2ITHP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
NEGHOLOK_00952	349741.Amuc_1997	4.29e-256	701.0	28HK0@1|root,2Z7V0@2|Bacteria,46TSH@74201|Verrucomicrobia,2IU3Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4105
NEGHOLOK_00953	349741.Amuc_1996	1.66e-143	404.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,DUF1906,PG_binding_1,Peptidase_M15_4
NEGHOLOK_00954	349741.Amuc_1995	0.0	973.0	COG3033@1|root,COG3033@2|Bacteria,46X9C@74201|Verrucomicrobia,2IV3F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Beta-eliminating lyase	-	-	4.1.99.1	ko:K01667	ko00380,map00380	-	R00673	RC00209,RC00355	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NEGHOLOK_00955	697282.Mettu_2046	1.03e-34	136.0	COG0515@1|root,COG0515@2|Bacteria,1PJRR@1224|Proteobacteria,1RMDQ@1236|Gammaproteobacteria,1XE9V@135618|Methylococcales	135618|Methylococcales	KLT	Tyrosine-protein kinase, subgroup, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
NEGHOLOK_00956	349741.Amuc_1993	1.14e-227	627.0	COG2958@1|root,COG2958@2|Bacteria,46ZH0@74201|Verrucomicrobia,2IU9M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00957	349741.Amuc_1992	5.51e-211	584.0	COG1277@1|root,COG1277@2|Bacteria,46VKD@74201|Verrucomicrobia,2IUKU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
NEGHOLOK_00958	349741.Amuc_1991	4.01e-160	448.0	COG2818@1|root,COG2818@2|Bacteria,46SS9@74201|Verrucomicrobia,2IUGS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Methyladenine glycosylase	-	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
NEGHOLOK_00959	349741.Amuc_1990	7.03e-178	497.0	COG0345@1|root,COG0345@2|Bacteria,46T4K@74201|Verrucomicrobia,2IUB9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyrroline-5-carboxylate reductase dimerisation	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NEGHOLOK_00962	349741.Amuc_1987	6.75e-245	672.0	COG1657@1|root,COG1657@2|Bacteria,46UYQ@74201|Verrucomicrobia,2ITJS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	PFAM Prenyltransferase squalene oxidase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00963	349741.Amuc_1986	2.94e-131	375.0	2AW0Q@1|root,31MVA@2|Bacteria,46X6M@74201|Verrucomicrobia,2IUQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00964	349741.Amuc_1985	0.0	1582.0	COG1196@1|root,COG1196@2|Bacteria,46TP5@74201|Verrucomicrobia,2IWNP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00965	349741.Amuc_1984	0.0	1372.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,46XAD@74201|Verrucomicrobia,2IV6P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	MM_CoA_mutase
NEGHOLOK_00966	349741.Amuc_1983	0.0	1408.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,46TP8@74201|Verrucomicrobia,2IU9J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Methylmalonyl-CoA mutase	-	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
NEGHOLOK_00969	349741.Amuc_1977	4.45e-225	619.0	COG1092@1|root,COG1092@2|Bacteria,46SYW@74201|Verrucomicrobia,2ITU3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NEGHOLOK_00970	349741.Amuc_1976	2.72e-261	716.0	COG0790@1|root,COG0790@2|Bacteria,46ZHX@74201|Verrucomicrobia,2IUWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	COG0790 FOG TPR repeat, SEL1 subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
NEGHOLOK_00971	349741.Amuc_1975	0.0	1001.0	COG0166@1|root,COG0166@2|Bacteria,46SUH@74201|Verrucomicrobia,2ITZ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglucose isomerase	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NEGHOLOK_00972	349741.Amuc_1974	0.0	1801.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,46TNN@74201|Verrucomicrobia,2ITZ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	-	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
NEGHOLOK_00973	349741.Amuc_1973	1.22e-143	404.0	COG2360@1|root,COG2360@2|Bacteria,46VHR@74201|Verrucomicrobia,2IUHM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
NEGHOLOK_00974	349741.Amuc_1972	1.62e-256	702.0	COG1194@1|root,COG1194@2|Bacteria,46SR4@74201|Verrucomicrobia,2ITPI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
NEGHOLOK_00975	349741.Amuc_1971	1.87e-218	604.0	COG0169@1|root,COG0169@2|Bacteria,46SVF@74201|Verrucomicrobia,2IU86@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NEGHOLOK_00977	349741.Amuc_1970	0.0	2369.0	COG0209@1|root,COG0209@2|Bacteria,46SG4@74201|Verrucomicrobia,2IWJ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
NEGHOLOK_00979	349741.Amuc_1968	1.11e-180	501.0	COG5522@1|root,COG5522@2|Bacteria,46WTQ@74201|Verrucomicrobia,2IW7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
NEGHOLOK_00980	349741.Amuc_1967	1.12e-116	334.0	COG3118@1|root,COG3118@2|Bacteria	2|Bacteria	O	belongs to the thioredoxin family	agmK	-	1.8.1.8	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko03110	-	-	-	Arylsulfotrans,TPR_8,Thioredoxin
NEGHOLOK_00982	349741.Amuc_1965	2.52e-281	770.0	COG0527@1|root,COG0527@2|Bacteria,46SIS@74201|Verrucomicrobia,2ITJM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	-	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NEGHOLOK_00983	349741.Amuc_1964	0.0	882.0	COG0077@1|root,COG0460@1|root,COG0077@2|Bacteria,COG0460@2|Bacteria,46SIY@74201|Verrucomicrobia,2ITHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Homoserine dehydrogenase	-	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NEGHOLOK_00985	349741.Amuc_1963	2.34e-108	313.0	COG3610@1|root,COG3610@2|Bacteria,46WV7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Threonine/Serine exporter, ThrE	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
NEGHOLOK_00986	349741.Amuc_1962	4.75e-171	479.0	COG2966@1|root,COG2966@2|Bacteria,46W6N@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE
NEGHOLOK_00987	349741.Amuc_1961	0.0	2465.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,46TG1@74201|Verrucomicrobia,2ITWA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
NEGHOLOK_00988	349741.Amuc_1960	2.15e-140	398.0	COG4733@1|root,COG4733@2|Bacteria,46TXW@74201|Verrucomicrobia,2IWPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	PA14	-	-	-	-	-	-	-	-	-	-	-	-	PA14
NEGHOLOK_00991	670487.Ocepr_1923	1.33e-71	232.0	28NDS@1|root,2ZBGH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4236
NEGHOLOK_00992	349741.Amuc_1958	2.83e-93	273.0	arCOG05276@1|root,3195F@2|Bacteria,46W1H@74201|Verrucomicrobia	74201|Verrucomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_00993	349741.Amuc_1957	0.0	913.0	COG1102@1|root,COG2364@1|root,COG1102@2|Bacteria,COG2364@2|Bacteria	2|Bacteria	F	Psort location Cytoplasmic, score	mmyX	-	5.3.1.12	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.2	-	-	AAA_28,Cytidylate_kin2,MFS_2
NEGHOLOK_00994	349741.Amuc_1956	8.23e-112	321.0	COG2606@1|root,COG2606@2|Bacteria	2|Bacteria	S	Cys-tRNA(Pro) hydrolase activity	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NEGHOLOK_00996	349741.Amuc_1954	4.32e-173	482.0	COG0518@1|root,COG0518@2|Bacteria,46V9Z@74201|Verrucomicrobia,2IW67@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
NEGHOLOK_00997	349741.Amuc_1953	7.35e-119	339.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
NEGHOLOK_00998	349741.Amuc_1952	1.06e-47	157.0	COG5522@1|root,COG5522@2|Bacteria,46WTQ@74201|Verrucomicrobia,2IW7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
NEGHOLOK_00999	349741.Amuc_1952	2.41e-99	291.0	COG5522@1|root,COG5522@2|Bacteria,46WTQ@74201|Verrucomicrobia,2IW7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Integral membrane protein (intg_mem_TP0381)	-	-	-	-	-	-	-	-	-	-	-	-	Intg_mem_TP0381
NEGHOLOK_01000	349741.Amuc_1951	9.03e-270	738.0	COG1902@1|root,COG1902@2|Bacteria,46SGZ@74201|Verrucomicrobia,2ITH2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN
NEGHOLOK_01001	349741.Amuc_1950	2e-148	417.0	COG0512@1|root,COG0512@2|Bacteria,46SN1@74201|Verrucomicrobia,2IU46@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Peptidase C26	-	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NEGHOLOK_01002	349741.Amuc_1949	2.45e-245	673.0	COG0147@1|root,COG0147@2|Bacteria	2|Bacteria	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4,Anth_synt_I_N,Chorismate_bind
NEGHOLOK_01003	349741.Amuc_1948	7.87e-150	421.0	COG0115@1|root,COG0115@2|Bacteria	2|Bacteria	E	branched-chain-amino-acid transaminase activity	-	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
NEGHOLOK_01004	349741.Amuc_1947	1.64e-314	853.0	COG2942@1|root,COG2942@2|Bacteria,46UIM@74201|Verrucomicrobia,2ITK6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
NEGHOLOK_01005	349741.Amuc_1946	1.38e-223	615.0	COG0329@1|root,COG0329@2|Bacteria,46UHJ@74201|Verrucomicrobia,2IU2T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
NEGHOLOK_01006	349741.Amuc_1945	0.0	1003.0	2C7EB@1|root,347YC@2|Bacteria,46W4Z@74201|Verrucomicrobia,2IUKP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01007	349741.Amuc_1944	2.65e-196	545.0	COG2084@1|root,COG2084@2|Bacteria,46U4D@74201|Verrucomicrobia,2IUCN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
NEGHOLOK_01008	349741.Amuc_1943	0.0	1491.0	COG0457@1|root,COG1196@1|root,COG0457@2|Bacteria,COG1196@2|Bacteria,46T1H@74201|Verrucomicrobia,2IUR7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_8
NEGHOLOK_01009	349741.Amuc_1942	1.53e-304	830.0	COG2195@1|root,COG2195@2|Bacteria	2|Bacteria	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
NEGHOLOK_01010	349741.Amuc_1941	0.0	927.0	COG0015@1|root,COG0015@2|Bacteria,46UUE@74201|Verrucomicrobia,2ITG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Adenylosuccinate lyase C-terminus	-	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NEGHOLOK_01011	349741.Amuc_1940	2.52e-102	296.0	COG5465@1|root,COG5465@2|Bacteria	2|Bacteria	S	Putative bacterial sensory transduction regulator	MA20_05485	-	-	-	-	-	-	-	-	-	-	-	YbjN
NEGHOLOK_01012	349741.Amuc_1939	1.12e-248	684.0	COG0845@1|root,COG0845@2|Bacteria,46VEA@74201|Verrucomicrobia,2IUBR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
NEGHOLOK_01013	349741.Amuc_1938	0.0	1837.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,46URE@74201|Verrucomicrobia,2ITXE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Helix-hairpin-helix class 2 (Pol1 family) motifs	-	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NEGHOLOK_01014	349741.Amuc_1937	1.82e-125	357.0	COG0634@1|root,COG0634@2|Bacteria,46T02@74201|Verrucomicrobia,2IUJK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NEGHOLOK_01016	349741.Amuc_1935	6.48e-142	400.0	COG1247@1|root,COG1247@2|Bacteria,46T83@74201|Verrucomicrobia,2IURQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NEGHOLOK_01017	349741.Amuc_1934	7.56e-246	677.0	COG3489@1|root,COG3489@2|Bacteria,46UF7@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Imelysin	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M75
NEGHOLOK_01018	349741.Amuc_1933	0.0	1004.0	COG3488@1|root,COG3488@2|Bacteria,46T3U@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Di-haem oxidoreductase, putative peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	DHOR
NEGHOLOK_01019	349741.Amuc_1932	2.43e-264	723.0	COG0251@1|root,COG0251@2|Bacteria,46V5Y@74201|Verrucomicrobia,2IW47@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Endoribonuclease L-PSP	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuc_L-PSP
NEGHOLOK_01020	349741.Amuc_1931	4.39e-219	605.0	COG4606@1|root,COG4606@2|Bacteria	2|Bacteria	P	iron ion homeostasis	yclN	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NEGHOLOK_01021	349741.Amuc_1930	2.03e-227	628.0	COG4605@1|root,COG4605@2|Bacteria	2|Bacteria	P	iron ion homeostasis	fatC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NEGHOLOK_01022	349741.Amuc_1929	1.06e-180	503.0	COG4604@1|root,COG4604@2|Bacteria	2|Bacteria	P	ABC transporter, ATP-binding protein	yclP	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NEGHOLOK_01023	349741.Amuc_1928	2.42e-209	580.0	COG4607@1|root,COG4607@2|Bacteria	2|Bacteria	P	iron ion transport	fatB	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NEGHOLOK_01024	349741.Amuc_1927	2.69e-185	515.0	COG1333@1|root,COG1333@2|Bacteria	2|Bacteria	O	cytochrome c biogenesis protein	ccs1	-	-	ko:K07399	-	-	-	-	ko00000	-	-	-	ResB
NEGHOLOK_01025	349741.Amuc_1926	0.0	1164.0	COG0755@1|root,COG0755@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
NEGHOLOK_01026	349741.Amuc_1925	2.52e-237	651.0	COG4763@1|root,COG4763@2|Bacteria,46X0A@74201|Verrucomicrobia,2IWAP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_01027	349741.Amuc_1924	0.0	1403.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_01028	349741.Amuc_1923	4.58e-103	298.0	COG5512@1|root,COG5512@2|Bacteria,46WKB@74201|Verrucomicrobia,2IUW6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF721)	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
NEGHOLOK_01029	349741.Amuc_1922	4.64e-52	163.0	COG1141@1|root,COG1141@2|Bacteria,46T2D@74201|Verrucomicrobia,2IURJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_13
NEGHOLOK_01030	349741.Amuc_1921	0.0	1266.0	COG0815@1|root,COG0815@2|Bacteria,46SPW@74201|Verrucomicrobia,2IU1H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Carbon-nitrogen hydrolase	-	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
NEGHOLOK_01031	349741.Amuc_1920	1.56e-176	492.0	COG3698@1|root,COG3698@2|Bacteria,46W6D@74201|Verrucomicrobia,2IUTV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
NEGHOLOK_01032	349741.Amuc_1919	1.1e-228	628.0	COG1208@1|root,COG1208@2|Bacteria,46SJP@74201|Verrucomicrobia,2IU9T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NEGHOLOK_01033	349741.Amuc_1918	0.0	867.0	COG0764@1|root,COG0774@1|root,COG0764@2|Bacteria,COG0774@2|Bacteria,46SG1@74201|Verrucomicrobia,2ITYH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis	fabZ	-	3.5.1.108,4.2.1.59	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	M00060,M00083	R04428,R04535,R04537,R04544,R04568,R04587,R04954,R04965	RC00166,RC00300,RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	-	-	-	FabA,LpxC
NEGHOLOK_01034	349741.Amuc_1917	1.75e-229	632.0	COG0524@1|root,COG0524@2|Bacteria,46U0Y@74201|Verrucomicrobia,2IU19@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
NEGHOLOK_01035	349741.Amuc_1916	2.1e-78	233.0	COG0239@1|root,COG0239@2|Bacteria	2|Bacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
NEGHOLOK_01036	349741.Amuc_1911	8.55e-275	751.0	COG1454@1|root,COG1454@2|Bacteria,46TD9@74201|Verrucomicrobia,2IUNH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NEGHOLOK_01040	349741.Amuc_1906	9.16e-208	575.0	COG4974@1|root,COG4974@2|Bacteria,46SSD@74201|Verrucomicrobia,2ITH5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NEGHOLOK_01041	349741.Amuc_1905	2.71e-269	738.0	COG3392@1|root,COG3392@2|Bacteria,46WWM@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM D12 class N6 adenine-specific DNA methyltransferase	-	-	2.1.1.72	ko:K07318	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	MethyltransfD12
NEGHOLOK_01043	349741.Amuc_1903	2.08e-240	660.0	2C4R5@1|root,2Z7JK@2|Bacteria	2|Bacteria	S	Psort location Cytoplasmic, score	BT0173	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
NEGHOLOK_01044	349741.Amuc_1902	5.27e-170	474.0	COG0822@1|root,COG0822@2|Bacteria	2|Bacteria	C	iron-sulfur transferase activity	BT0174	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NEGHOLOK_01045	349741.Amuc_1901	2.43e-201	556.0	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	lpxG	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NEGHOLOK_01047	349741.Amuc_1899	2.38e-99	288.0	COG0369@1|root,COG0369@2|Bacteria	2|Bacteria	C	hydroxylamine reductase activity	cysJ	-	1.8.1.2	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R00858	RC00065	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_1,Flavodoxin_1,NAD_binding_1
NEGHOLOK_01049	349741.Amuc_1897	1.25e-261	716.0	COG0082@1|root,COG0082@2|Bacteria,46SEA@74201|Verrucomicrobia,2ITMN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NEGHOLOK_01050	349741.Amuc_1896	1.33e-52	166.0	COG0776@1|root,COG0776@2|Bacteria,46T4R@74201|Verrucomicrobia,2IUNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	-	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NEGHOLOK_01051	349741.Amuc_1895	4.73e-303	827.0	COG0766@1|root,COG0766@2|Bacteria,46S6Q@74201|Verrucomicrobia,2ITRZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NEGHOLOK_01052	349741.Amuc_1894	2.29e-315	858.0	COG0128@1|root,COG0128@2|Bacteria,46SFD@74201|Verrucomicrobia,2ITVM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NEGHOLOK_01053	349741.Amuc_1893	1.28e-85	251.0	COG0727@1|root,COG0727@2|Bacteria,46W4U@74201|Verrucomicrobia,2IUJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NEGHOLOK_01056	349741.Amuc_1890	2.05e-191	532.0	COG1968@1|root,COG1968@2|Bacteria,46SP6@74201|Verrucomicrobia,2IURU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Bacitracin resistance protein BacA	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NEGHOLOK_01057	349741.Amuc_1889	7.46e-238	657.0	COG0805@1|root,COG0805@2|Bacteria,46T26@74201|Verrucomicrobia,2ITNJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
NEGHOLOK_01058	349741.Amuc_1888	0.0	876.0	COG0008@1|root,COG1384@1|root,COG0008@2|Bacteria,COG1384@2|Bacteria,46SJ3@74201|Verrucomicrobia,2ITYY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NEGHOLOK_01059	349741.Amuc_1887	0.0	1462.0	COG3264@1|root,COG3264@2|Bacteria	2|Bacteria	M	cellular water homeostasis	kefA	GO:0005575,GO:0005623,GO:0005886,GO:0006884,GO:0008150,GO:0008361,GO:0009987,GO:0009992,GO:0016020,GO:0016043,GO:0019725,GO:0030104,GO:0032535,GO:0042592,GO:0044464,GO:0048878,GO:0055082,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066	-	ko:K05802,ko:K22051	-	-	-	-	ko00000,ko02000	1.A.23.1.1,1.A.23.1.2,1.A.23.1.3	-	-	DUF3772,MS_channel,MscS_TM,MscS_porin
NEGHOLOK_01060	349741.Amuc_1886	1.78e-97	283.0	COG0780@1|root,COG0780@2|Bacteria,46SYQ@74201|Verrucomicrobia,2IUI4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	QueF-like protein	queF	-	1.7.1.13	ko:K09457	ko00790,ko01100,map00790,map01100	-	R07605	RC01875	ko00000,ko00001,ko01000,ko03016	-	-	-	QueF
NEGHOLOK_01061	349741.Amuc_1885	1.02e-159	447.0	COG0603@1|root,COG0603@2|Bacteria,46SEU@74201|Verrucomicrobia,2IU6V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Queuosine biosynthesis protein QueC	queC	-	6.3.4.20	ko:K06920	ko00790,ko01100,map00790,map01100	-	R09978	RC00959	ko00000,ko00001,ko01000,ko03016	-	-	-	QueC
NEGHOLOK_01062	349741.Amuc_1884	4.51e-141	399.0	COG0125@1|root,COG0125@2|Bacteria,46YZ4@74201|Verrucomicrobia,2IUD6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
NEGHOLOK_01063	349741.Amuc_1883	0.0	922.0	COG1236@1|root,COG1236@2|Bacteria,46SQ0@74201|Verrucomicrobia,2ITW2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Beta-Casp domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta-Casp,Lactamase_B,RMMBL
NEGHOLOK_01064	349741.Amuc_1882	1.23e-62	191.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1232
NEGHOLOK_01065	349741.Amuc_1881	1.05e-160	450.0	2DDRS@1|root,2ZJ0Y@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
NEGHOLOK_01066	349741.Amuc_1880	4.25e-306	835.0	COG0538@1|root,COG0538@2|Bacteria,46Z6W@74201|Verrucomicrobia,2IVFR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Isocitrate/isopropylmalate dehydrogenase	-	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NEGHOLOK_01067	349741.Amuc_1879	1.6e-270	740.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_01068	349741.Amuc_1878	1.68e-61	188.0	COG0346@1|root,COG0346@2|Bacteria,46XR0@74201|Verrucomicrobia,2IWE8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K07032	-	-	-	-	ko00000	-	-	-	Glyoxalase
NEGHOLOK_01069	349741.Amuc_1876	0.0	1416.0	COG2010@1|root,COG2993@1|root,COG2010@2|Bacteria,COG2993@2|Bacteria,46TWP@74201|Verrucomicrobia,2ITWT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C,Cytochrome_CBB3,F5_F8_type_C
NEGHOLOK_01070	349741.Amuc_1875	1.57e-298	814.0	COG4531@1|root,COG4531@2|Bacteria,46SME@74201|Verrucomicrobia,2ITX9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ABC-type Zn2 transport system, periplasmic component surface adhesin	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01071	349741.Amuc_1874	3.17e-157	441.0	COG2010@1|root,COG2010@2|Bacteria	2|Bacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	CopD,Cytochrome_CBB3
NEGHOLOK_01073	349741.Amuc_1872	9.16e-312	850.0	COG5557@1|root,COG5557@2|Bacteria,46S9S@74201|Verrucomicrobia,2ITK9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Polysulphide reductase, NrfD	-	-	-	ko:K00185	-	-	-	-	ko00000	5.A.3	-	-	NrfD
NEGHOLOK_01074	349741.Amuc_1871	1.22e-249	684.0	COG1169@1|root,COG1169@2|Bacteria,46YW2@74201|Verrucomicrobia,2IU6K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
NEGHOLOK_01075	349741.Amuc_1870	0.0	1708.0	COG1501@1|root,COG1501@2|Bacteria,46TKY@74201|Verrucomicrobia,2IU43@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 31	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
NEGHOLOK_01076	349741.Amuc_1869	1.25e-315	859.0	COG0297@1|root,COG0297@2|Bacteria,46Z3D@74201|Verrucomicrobia,2IUHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NEGHOLOK_01077	349741.Amuc_1868	1.22e-292	798.0	COG1449@1|root,COG1449@2|Bacteria,46XBE@74201|Verrucomicrobia,2IVAX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 57	-	-	3.2.1.1	ko:K07405	ko00500,ko01100,map00500,map01100	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH57	-	Glyco_hydro_57
NEGHOLOK_01078	349741.Amuc_1867	8.02e-130	368.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,2IUCF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NEGHOLOK_01079	349741.Amuc_1866	1.28e-93	273.0	COG0848@1|root,COG0848@2|Bacteria,46T7H@74201|Verrucomicrobia,2IUR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
NEGHOLOK_01080	349741.Amuc_1865	2.29e-136	387.0	COG0811@1|root,COG0811@2|Bacteria,46T1R@74201|Verrucomicrobia,2IUJU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
NEGHOLOK_01081	349741.Amuc_1864	5.53e-285	779.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1983
NEGHOLOK_01082	349741.Amuc_1863	3.77e-118	337.0	COG0629@1|root,COG0629@2|Bacteria,46VGA@74201|Verrucomicrobia,2IUK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Single-strand binding protein family	-	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
NEGHOLOK_01083	349741.Amuc_1862	8.95e-316	858.0	COG0151@1|root,COG0151@2|Bacteria,46SGJ@74201|Verrucomicrobia,2ITXH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NEGHOLOK_01084	349741.Amuc_1861	5.77e-145	408.0	COG3738@1|root,COG3738@2|Bacteria,46X3M@74201|Verrucomicrobia,2IUCP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1287)	-	-	-	ko:K09974	-	-	-	-	ko00000	-	-	-	DUF1287
NEGHOLOK_01085	349741.Amuc_1860	0.0	1096.0	COG2759@1|root,COG2759@2|Bacteria,46SGS@74201|Verrucomicrobia	74201|Verrucomicrobia	H	Formate--tetrahydrofolate ligase	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NEGHOLOK_01086	349741.Amuc_1859	9.98e-223	613.0	COG1893@1|root,COG1893@2|Bacteria,46SK2@74201|Verrucomicrobia,2IU3H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
NEGHOLOK_01087	349741.Amuc_1857	1.65e-208	576.0	COG0457@1|root,COG0457@2|Bacteria,46VY0@74201|Verrucomicrobia,2IUSH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01088	349741.Amuc_1856	1.4e-185	515.0	COG0639@1|root,COG0639@2|Bacteria,46TA5@74201|Verrucomicrobia,2ITKJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos_2
NEGHOLOK_01089	349741.Amuc_1855	0.0	884.0	COG0601@1|root,COG0601@2|Bacteria,46TSV@74201|Verrucomicrobia,2ITNK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13894	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
NEGHOLOK_01090	349741.Amuc_1854	0.0	1049.0	COG4239@1|root,COG4239@2|Bacteria,46UMY@74201|Verrucomicrobia,2ITTS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13895	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	BPD_transp_1
NEGHOLOK_01091	349741.Amuc_1853	0.0	1515.0	COG4166@1|root,COG4166@2|Bacteria,46UFF@74201|Verrucomicrobia,2ITVT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
NEGHOLOK_01092	349741.Amuc_1852	1.82e-229	632.0	COG0444@1|root,COG0444@2|Bacteria,46YTM@74201|Verrucomicrobia,2IU2Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NEGHOLOK_01093	349741.Amuc_1851	6.48e-244	669.0	COG4608@1|root,COG4608@2|Bacteria,46U8E@74201|Verrucomicrobia,2ITPK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NEGHOLOK_01094	349741.Amuc_1850	1.27e-273	747.0	COG0787@1|root,COG0787@2|Bacteria,46SM1@74201|Verrucomicrobia,2IU27@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	-	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NEGHOLOK_01096	676032.FN3523_1645	2.57e-120	354.0	COG3586@1|root,COG3586@2|Bacteria,1R4TU@1224|Proteobacteria,1RQ7K@1236|Gammaproteobacteria,4610H@72273|Thiotrichales	72273|Thiotrichales	L	Protein of unknown function DUF262	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01097	349741.Amuc_1849	1.07e-208	578.0	COG0697@1|root,COG0697@2|Bacteria,46U7M@74201|Verrucomicrobia,2IVXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NEGHOLOK_01098	1506583.JQJY01000005_gene2178	1.81e-282	803.0	COG2132@1|root,COG2132@2|Bacteria,4NE3N@976|Bacteroidetes,1HWXY@117743|Flavobacteriia,2NT1D@237|Flavobacterium	976|Bacteroidetes	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
NEGHOLOK_01099	349741.Amuc_1847	0.0	874.0	COG0232@1|root,COG0232@2|Bacteria,46UHP@74201|Verrucomicrobia,2ITWR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphohydrolase-associated domain	-	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NEGHOLOK_01100	761193.Runsl_4064	7.68e-234	680.0	COG0265@1|root,COG0265@2|Bacteria,4NGFM@976|Bacteroidetes,47NN1@768503|Cytophagia	976|Bacteroidetes	O	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,PDZ_2
NEGHOLOK_01101	349741.Amuc_1844	1e-219	607.0	COG0265@1|root,COG0265@2|Bacteria,46YDU@74201|Verrucomicrobia,2IUZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
NEGHOLOK_01103	349741.Amuc_1842	1.07e-138	392.0	COG1595@1|root,COG1595@2|Bacteria,46WAM@74201|Verrucomicrobia,2IWJD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
NEGHOLOK_01104	349741.Amuc_1841	1.08e-220	609.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	ytpP	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	2.7.1.180,5.3.4.1	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko01000,ko02000,ko03110	5.A.1.2	-	-	Thioredoxin
NEGHOLOK_01105	349741.Amuc_1840	0.0	1240.0	COG0422@1|root,COG0422@2|Bacteria,46S5R@74201|Verrucomicrobia,2ITWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiC-associated domain	-	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC-associated,ThiC_Rad_SAM
NEGHOLOK_01106	349741.Amuc_1839	0.0	1174.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,2ITMQ@203494|Verrucomicrobiae	74201|Verrucomicrobia	P	E1-E2 ATPase	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase,YHS
NEGHOLOK_01107	349741.Amuc_1838	7.29e-60	184.0	COG1937@1|root,COG1937@2|Bacteria	2|Bacteria	S	negative regulation of transcription, DNA-templated	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NEGHOLOK_01108	349741.Amuc_1836	2.34e-134	381.0	COG1595@1|root,COG1595@2|Bacteria,46SZG@74201|Verrucomicrobia,2IUFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ECF sigma factor	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NEGHOLOK_01109	349741.Amuc_1835	0.0	1375.0	COG4409@1|root,COG4409@2|Bacteria,46XBR@74201|Verrucomicrobia,2IVC8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	N-terminal domain of BNR-repeat neuraminidase	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,BNR_assoc_N
NEGHOLOK_01110	349741.Amuc_1834	1.59e-121	346.0	2ERDI@1|root,2ZSFS@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01111	349741.Amuc_1833	0.0	1249.0	COG0738@1|root,COG0738@2|Bacteria,46VVQ@74201|Verrucomicrobia,2IU7A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NEGHOLOK_01112	349741.Amuc_1832	0.0	1218.0	COG2407@1|root,COG2407@2|Bacteria,46ZAF@74201|Verrucomicrobia,2ITQK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
NEGHOLOK_01114	349741.Amuc_1830	0.0	941.0	COG1070@1|root,COG1070@2|Bacteria,46S5Z@74201|Verrucomicrobia,2IUPF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.51	ko:K00879	ko00051,ko01120,map00051,map01120	-	R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NEGHOLOK_01115	349741.Amuc_1829	1.03e-201	557.0	COG0235@1|root,COG0235@2|Bacteria,46UR3@74201|Verrucomicrobia,2IVPG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NEGHOLOK_01119	349741.Amuc_1555	0.0	1379.0	COG0556@1|root,COG0556@2|Bacteria,46SF2@74201|Verrucomicrobia,2ITYA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NEGHOLOK_01120	349741.Amuc_1556	2.91e-38	128.0	COG0291@1|root,COG0291@2|Bacteria,46TCI@74201|Verrucomicrobia,2IUW5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L35	-	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NEGHOLOK_01121	349741.Amuc_1557	6.39e-80	238.0	COG0292@1|root,COG0292@2|Bacteria,46SZW@74201|Verrucomicrobia,2IUFE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NEGHOLOK_01122	349741.Amuc_1558	0.0	959.0	COG0750@1|root,COG0750@2|Bacteria,46S9B@74201|Verrucomicrobia,2ITH1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M50	-	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_M50
NEGHOLOK_01125	349741.Amuc_1561	0.0	1979.0	COG1074@1|root,COG1074@2|Bacteria,46SF0@74201|Verrucomicrobia,2ITYF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	UvrD/REP helicase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NEGHOLOK_01126	349741.Amuc_1562	0.0	1893.0	COG2887@1|root,COG3893@1|root,COG2887@2|Bacteria,COG3893@2|Bacteria,46SDQ@74201|Verrucomicrobia,2ITHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
NEGHOLOK_01127	349741.Amuc_1563	5.31e-212	586.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	MA20_36650	-	-	-	-	-	-	-	-	-	-	-	EamA
NEGHOLOK_01128	349741.Amuc_1564	1.52e-191	530.0	28IMK@1|root,2Z8N2@2|Bacteria	2|Bacteria	L	Dam-replacing family	dpnC	-	3.1.21.4	ko:K01155	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DpnI
NEGHOLOK_01129	349741.Amuc_1565	0.0	4135.0	COG2373@1|root,COG2373@2|Bacteria,46U24@74201|Verrucomicrobia,2IVD9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alpha-2-macroglobulin family	-	-	-	-	-	-	-	-	-	-	-	-	A2M,A2M_N,A2M_N_2,A2M_comp,Thiol-ester_cl
NEGHOLOK_01130	349741.Amuc_1566	3.91e-289	789.0	COG1979@1|root,COG1979@2|Bacteria,46V6X@74201|Verrucomicrobia,2IWPW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NEGHOLOK_01132	349741.Amuc_1567	2.89e-123	352.0	COG0350@1|root,COG0350@2|Bacteria,46XK4@74201|Verrucomicrobia,2IW45@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1
NEGHOLOK_01135	349741.Amuc_1570	5.98e-212	586.0	2EKXK@1|root,33EM4@2|Bacteria,46WCN@74201|Verrucomicrobia,2IUG6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01136	349741.Amuc_1571	9.76e-153	429.0	COG1214@1|root,COG1214@2|Bacteria,46T3K@74201|Verrucomicrobia,2IUPV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Glycoprotease family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M22
NEGHOLOK_01137	349741.Amuc_1572	4.28e-274	749.0	COG0372@1|root,COG0372@2|Bacteria,46SBV@74201|Verrucomicrobia,2ITKN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NEGHOLOK_01138	349741.Amuc_1574	3.86e-112	321.0	COG0219@1|root,COG0219@2|Bacteria,46SYZ@74201|Verrucomicrobia,2IUCK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	-	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NEGHOLOK_01139	349741.Amuc_1575	4.12e-139	392.0	COG0417@1|root,COG0417@2|Bacteria,46SS2@74201|Verrucomicrobia,2IUC2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RNase_H superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RNase_H_2
NEGHOLOK_01140	349741.Amuc_1576	6.68e-103	298.0	COG0691@1|root,COG0691@2|Bacteria,46VGJ@74201|Verrucomicrobia,2IUAH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NEGHOLOK_01141	349741.Amuc_1577	1.5e-44	144.0	COG1758@1|root,COG1758@2|Bacteria,46W29@74201|Verrucomicrobia,2IUQD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	RNA polymerase activity	-	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
NEGHOLOK_01142	349741.Amuc_1578	3.51e-136	385.0	COG1187@1|root,COG1187@2|Bacteria,46V8C@74201|Verrucomicrobia,2IU9S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.20	ko:K06181	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NEGHOLOK_01143	349741.Amuc_1579	1.26e-214	591.0	28NXH@1|root,2ZBV3@2|Bacteria,46TF0@74201|Verrucomicrobia,2IUAE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01144	349741.Amuc_1580	1.3e-104	302.0	COG0105@1|root,COG0105@2|Bacteria,46VKB@74201|Verrucomicrobia,2IUDM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NDK	-	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
NEGHOLOK_01145	349741.Amuc_1581	1.71e-201	557.0	COG1216@1|root,COG1216@2|Bacteria,46W61@74201|Verrucomicrobia,2IWK3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01146	349741.Amuc_1582	4.12e-225	620.0	COG0463@1|root,COG0463@2|Bacteria,46SPS@74201|Verrucomicrobia,2IUQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01147	1396141.BATP01000002_gene4824	1.34e-07	57.8	COG4968@1|root,COG4968@2|Bacteria,46WJ1@74201|Verrucomicrobia,2IUWN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NEGHOLOK_01148	349741.Amuc_1584	7.26e-285	780.0	COG1459@1|root,COG1459@2|Bacteria,46U60@74201|Verrucomicrobia,2IWMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
NEGHOLOK_01149	349741.Amuc_1585	0.0	1090.0	COG2804@1|root,COG2804@2|Bacteria,46UFR@74201|Verrucomicrobia,2ITMV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II secretion system (T2SS), protein E, N-terminal domain	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
NEGHOLOK_01150	349741.Amuc_1586	0.0	1020.0	COG2804@1|root,COG2804@2|Bacteria,46SDR@74201|Verrucomicrobia,2IU2P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II/IV secretion system protein	-	-	-	ko:K02652	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE,T2SSE_N
NEGHOLOK_01151	349741.Amuc_1587	1.04e-244	671.0	COG0042@1|root,COG0042@2|Bacteria,46SIG@74201|Verrucomicrobia,2ITHJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NEGHOLOK_01152	349741.Amuc_1588	2.83e-110	318.0	2CIV9@1|root,34A52@2|Bacteria,46W0H@74201|Verrucomicrobia,2IUYN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Control of competence regulator ComK, YlbF/YmcA	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NEGHOLOK_01153	349741.Amuc_1589	1.57e-280	766.0	COG0436@1|root,COG0436@2|Bacteria,46S4M@74201|Verrucomicrobia,2ITV6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_01154	349741.Amuc_1590	0.0	996.0	COG0728@1|root,COG0728@2|Bacteria,46SH1@74201|Verrucomicrobia,2IUHC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
NEGHOLOK_01155	349741.Amuc_1591	1.26e-271	742.0	COG0615@1|root,COG0615@2|Bacteria,46TM5@74201|Verrucomicrobia,2IVDW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
NEGHOLOK_01156	349741.Amuc_1592	1.74e-157	442.0	COG0605@1|root,COG0605@2|Bacteria,46SQF@74201|Verrucomicrobia,2IU40@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Iron/manganese superoxide dismutases, alpha-hairpin domain	-	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
NEGHOLOK_01157	349741.Amuc_1593	0.0	1004.0	COG1649@1|root,COG1649@2|Bacteria,46UQU@74201|Verrucomicrobia,2ITMK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyl hydrolase-like 10	-	-	-	-	-	-	-	-	-	-	-	-	GHL10
NEGHOLOK_01158	349741.Amuc_1594	9.28e-170	475.0	COG1691@1|root,COG1691@2|Bacteria,46SQC@74201|Verrucomicrobia,2IUDP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
NEGHOLOK_01159	349741.Amuc_1595	3.98e-190	528.0	COG1606@1|root,COG1606@2|Bacteria,46VAE@74201|Verrucomicrobia,2IUM5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	tRNA processing	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase
NEGHOLOK_01160	349741.Amuc_1596	2.37e-291	795.0	COG1641@1|root,COG1641@2|Bacteria,46THK@74201|Verrucomicrobia,2IUEA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NEGHOLOK_01161	349741.Amuc_1597	1.07e-238	656.0	COG0142@1|root,COG0142@2|Bacteria,46SKW@74201|Verrucomicrobia,2ITYJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Polyprenyl synthetase	-	-	2.5.1.90	ko:K02523	ko00900,ko01110,map00900,map01110	-	R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
NEGHOLOK_01162	349741.Amuc_1598	0.0	897.0	COG3104@1|root,COG3104@2|Bacteria,46UAC@74201|Verrucomicrobia,2IU1T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	POT family	-	-	-	ko:K03305	-	-	-	-	ko00000	2.A.17	-	-	PTR2
NEGHOLOK_01163	349741.Amuc_1599	0.0	1132.0	COG0760@1|root,COG0760@2|Bacteria,46T1I@74201|Verrucomicrobia,2IUT1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K03770	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2,SurA_N_3
NEGHOLOK_01164	349741.Amuc_1600	2.39e-126	359.0	COG2151@1|root,COG2151@2|Bacteria,46SWX@74201|Verrucomicrobia,2IU6Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pfam:DUF59	-	-	-	-	-	-	-	-	-	-	-	-	FeS_assembly_P
NEGHOLOK_01165	349741.Amuc_1601	7.43e-107	308.0	2AEKC@1|root,314G0@2|Bacteria,46XJ0@74201|Verrucomicrobia,2IW1N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01167	349741.Amuc_1603	3.12e-219	603.0	COG2755@1|root,COG2755@2|Bacteria,46Z4Z@74201|Verrucomicrobia,2IUPG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Domain of unknown function (DUF3472)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3472,DUF5077
NEGHOLOK_01168	349741.Amuc_1604	0.0	869.0	COG1007@1|root,COG1007@2|Bacteria,46ST5@74201|Verrucomicrobia,2IU1U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
NEGHOLOK_01169	349741.Amuc_1605	0.0	903.0	COG1008@1|root,COG1008@2|Bacteria,46SE4@74201|Verrucomicrobia,2ITG7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Proton-conducting membrane transporter	-	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
NEGHOLOK_01170	349741.Amuc_1606	0.0	1155.0	COG1009@1|root,COG1009@2|Bacteria,46SDU@74201|Verrucomicrobia,2ITQ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CP	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
NEGHOLOK_01171	349741.Amuc_1607	6.01e-61	188.0	COG0713@1|root,COG0713@2|Bacteria,46SX4@74201|Verrucomicrobia,2IUN3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
NEGHOLOK_01172	349741.Amuc_1608	6.53e-158	444.0	COG0839@1|root,COG0839@2|Bacteria,46VSH@74201|Verrucomicrobia,2IUHV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
NEGHOLOK_01173	349741.Amuc_1609	1.8e-124	355.0	COG1143@1|root,COG1143@2|Bacteria,46SNT@74201|Verrucomicrobia,2IU68@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
NEGHOLOK_01174	349741.Amuc_1610	1.04e-309	843.0	COG1005@1|root,COG1005@2|Bacteria,46SIJ@74201|Verrucomicrobia,2ITZ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
NEGHOLOK_01175	349741.Amuc_1611	0.0	1143.0	COG1034@1|root,COG3383@1|root,COG1034@2|Bacteria,COG3383@2|Bacteria,46S6S@74201|Verrucomicrobia,2ITJ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	-	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,NADH-G_4Fe-4S_3
NEGHOLOK_01176	349741.Amuc_1612	0.0	968.0	COG1894@1|root,COG1894@2|Bacteria,46S8J@74201|Verrucomicrobia,2ITYB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
NEGHOLOK_01177	349741.Amuc_1613	2.88e-142	400.0	COG1905@1|root,COG1905@2|Bacteria,46VMZ@74201|Verrucomicrobia,2IU8F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NEGHOLOK_01178	349741.Amuc_1614	3.6e-306	833.0	COG0649@1|root,COG0649@2|Bacteria,46SA0@74201|Verrucomicrobia,2IU02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoD	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
NEGHOLOK_01180	349741.Amuc_1616	0.0	930.0	COG0726@1|root,COG0726@2|Bacteria,46UVJ@74201|Verrucomicrobia,2IU4X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NEGHOLOK_01181	349741.Amuc_1617	0.0	1067.0	COG1055@1|root,COG1055@2|Bacteria,46S61@74201|Verrucomicrobia,2ITKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Putative Na+/H+ antiporter	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiport_3
NEGHOLOK_01182	349741.Amuc_1618	4.37e-141	398.0	COG0307@1|root,COG0307@2|Bacteria,46SU1@74201|Verrucomicrobia,2IUAK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Lumazine binding domain	-	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
NEGHOLOK_01183	349741.Amuc_1619	5.71e-202	559.0	COG2264@1|root,COG2264@2|Bacteria,46SYY@74201|Verrucomicrobia,2ITXU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L11 methyltransferase (PrmA)	-	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NEGHOLOK_01184	349741.Amuc_1620	0.0	2073.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	pmp21	-	-	-	-	-	-	-	-	-	-	-	Autotransporter,ChlamPMP_M,Chlam_PMP
NEGHOLOK_01185	349741.Amuc_1621	0.0	1318.0	COG1640@1|root,COG1640@2|Bacteria,46SX0@74201|Verrucomicrobia,2ITJ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NEGHOLOK_01187	349741.Amuc_1623	0.0	903.0	COG0621@1|root,COG0621@2|Bacteria,46S5U@74201|Verrucomicrobia,2ITS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Uncharacterized protein family UPF0004	-	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NEGHOLOK_01188	349741.Amuc_1624	0.0	910.0	COG1030@1|root,COG1030@2|Bacteria,46TAS@74201|Verrucomicrobia,2IU3S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	NfeD
NEGHOLOK_01189	349741.Amuc_1625	0.0	1150.0	COG0358@1|root,COG0358@2|Bacteria,46S6C@74201|Verrucomicrobia,2ITUJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,Toprim_2,Toprim_N,zf-CHC2
NEGHOLOK_01190	349741.Amuc_1626	0.0	1008.0	COG0568@1|root,COG0568@2|Bacteria,46S6M@74201|Verrucomicrobia,2ITQW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NEGHOLOK_01191	349741.Amuc_1627	3.72e-187	518.0	COG2173@1|root,COG2173@2|Bacteria,46VUM@74201|Verrucomicrobia,2IWEV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-ala-D-ala dipeptidase	-	-	3.4.13.22	ko:K08641	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	Peptidase_M15
NEGHOLOK_01194	349741.Amuc_1630	0.0	1132.0	COG0112@1|root,COG0112@2|Bacteria,46S5I@74201|Verrucomicrobia,2ITI6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc,LacAB_rpiB,SHMT
NEGHOLOK_01195	349741.Amuc_1631	0.0	1365.0	COG0793@1|root,COG0793@2|Bacteria,46S88@74201|Verrucomicrobia,2IU0C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	tail specific protease	-	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DUF3340,PDZ,Peptidase_S41
NEGHOLOK_01196	349741.Amuc_1632	8.06e-216	597.0	COG4589@1|root,COG4589@2|Bacteria,46SX9@74201|Verrucomicrobia,2IUDS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cytidylyltransferase family	-	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NEGHOLOK_01197	349741.Amuc_1633	0.0	1692.0	COG1643@1|root,COG1643@2|Bacteria,46TMT@74201|Verrucomicrobia,2ITY8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	ATP-dependent helicase C-terminal	-	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
NEGHOLOK_01198	349741.Amuc_1634	0.0	1410.0	COG0306@1|root,COG0306@2|Bacteria	2|Bacteria	P	phosphate transporter	-	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
NEGHOLOK_01199	349741.Amuc_1635	4.81e-311	847.0	COG1225@1|root,COG1225@2|Bacteria	2|Bacteria	O	peroxiredoxin activity	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NEGHOLOK_01200	349741.Amuc_1636	0.0	922.0	COG0617@1|root,COG0617@2|Bacteria,46S8B@74201|Verrucomicrobia,2ITTG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Poly A polymerase head domain	-	-	2.7.7.19	ko:K00970	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NEGHOLOK_01201	349741.Amuc_1637	0.0	1217.0	COG0366@1|root,COG0366@2|Bacteria,46URK@74201|Verrucomicrobia,2ITZW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
NEGHOLOK_01202	349741.Amuc_1638	0.0	1584.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
NEGHOLOK_01203	349741.Amuc_1639	0.0	1024.0	2AX66@1|root,31P4T@2|Bacteria,46XST@74201|Verrucomicrobia,2IWHH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01204	349741.Amuc_1640	7.21e-183	507.0	COG2121@1|root,COG2121@2|Bacteria,46SZ0@74201|Verrucomicrobia,2IUKE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF374)	-	-	-	ko:K09778	-	-	-	-	ko00000	-	-	-	DUF374
NEGHOLOK_01205	349741.Amuc_1641	7.21e-203	562.0	COG0190@1|root,COG0190@2|Bacteria,46TG7@74201|Verrucomicrobia,2ITSZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NEGHOLOK_01206	349741.Amuc_1642	2.91e-182	507.0	COG0623@1|root,COG0623@2|Bacteria,46ZBA@74201|Verrucomicrobia,2IW7X@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Enoyl-(Acyl carrier protein) reductase	-	-	1.3.1.10,1.3.1.9	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NEGHOLOK_01207	349741.Amuc_1643	1.84e-202	560.0	COG1597@1|root,COG1597@2|Bacteria,46SR5@74201|Verrucomicrobia,2IUED@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NEGHOLOK_01208	349741.Amuc_1644	1.2e-284	776.0	COG1305@1|root,COG1305@2|Bacteria,46XFC@74201|Verrucomicrobia,2IVRS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NEGHOLOK_01209	349741.Amuc_1645	8.69e-261	713.0	COG0042@1|root,COG0042@2|Bacteria,46TSS@74201|Verrucomicrobia,2ITU4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	ko:K05541	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NEGHOLOK_01210	349741.Amuc_1646	6.25e-288	786.0	COG0761@1|root,COG0761@2|Bacteria,46SAR@74201|Verrucomicrobia,2IU0D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IM	LytB protein	-	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
NEGHOLOK_01212	349741.Amuc_1648	2.34e-43	142.0	COG0268@1|root,COG0268@2|Bacteria,46WWC@74201|Verrucomicrobia,2IV02@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S20	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NEGHOLOK_01213	349741.Amuc_1649	7.83e-140	395.0	COG0637@1|root,COG0637@2|Bacteria,46VM3@74201|Verrucomicrobia,2IUCI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NEGHOLOK_01214	349741.Amuc_1650	0.0	1227.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,2ITSM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EH	Thiamine pyrophosphate enzyme, central domain	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NEGHOLOK_01217	349741.Amuc_1652	3.25e-223	614.0	COG0688@1|root,COG0688@2|Bacteria,46TND@74201|Verrucomicrobia,2ITXF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Phosphatidylserine decarboxylase	-	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NEGHOLOK_01218	349741.Amuc_1653	3.85e-152	427.0	COG0036@1|root,COG0036@2|Bacteria,46SVX@74201|Verrucomicrobia,2IU4U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Ribulose-phosphate 3 epimerase family	-	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NEGHOLOK_01219	349741.Amuc_1654	0.0	1755.0	COG0495@1|root,COG0495@2|Bacteria,46SF4@74201|Verrucomicrobia,2ITTI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Leucyl-tRNA synthetase, Domain 2	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NEGHOLOK_01220	349741.Amuc_1655	0.0	1150.0	COG3119@1|root,COG3119@2|Bacteria,46SHT@74201|Verrucomicrobia,2IUAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NEGHOLOK_01222	349741.Amuc_1657	7.45e-301	819.0	COG0019@1|root,COG0019@2|Bacteria,46TXE@74201|Verrucomicrobia,2ITUI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, C-terminal sheet domain	-	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NEGHOLOK_01223	349741.Amuc_1658	0.0	1293.0	COG1166@1|root,COG1166@2|Bacteria,46S4T@74201|Verrucomicrobia,2ITMU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N
NEGHOLOK_01224	349741.Amuc_1659	8.87e-269	735.0	COG0582@1|root,COG0582@2|Bacteria,46T2Q@74201|Verrucomicrobia,2IV0J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NEGHOLOK_01225	1158294.JOMI01000004_gene3502	3.64e-183	544.0	COG3250@1|root,COG3250@2|Bacteria,4NEDF@976|Bacteroidetes,2FMTQ@200643|Bacteroidia	976|Bacteroidetes	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NEGHOLOK_01226	349741.Amuc_1666	0.0	2584.0	COG3250@1|root,COG3250@2|Bacteria,46XA3@74201|Verrucomicrobia,2IV61@203494|Verrucomicrobiae	2|Bacteria	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,RicinB_lectin_2
NEGHOLOK_01227	349741.Amuc_1667	0.0	1679.0	COG3250@1|root,COG3250@2|Bacteria	2|Bacteria	G	beta-galactosidase activity	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,LRR_5,RicinB_lectin_2
NEGHOLOK_01228	349741.Amuc_1668	0.0	905.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,2ITKR@203494|Verrucomicrobiae	2|Bacteria	L	MgsA AAA+ ATPase C terminal	rarA	GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NEGHOLOK_01229	349741.Amuc_1669	0.0	1102.0	COG3525@1|root,COG3525@2|Bacteria,46ZK1@74201|Verrucomicrobia,2IVDU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PFAM Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_01231	349741.Amuc_1671	3.87e-301	821.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2IV1Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	-	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NEGHOLOK_01232	349741.Amuc_1672	3.67e-216	598.0	COG3317@1|root,COG3317@2|Bacteria,46WFV@74201|Verrucomicrobia,2IUW0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
NEGHOLOK_01233	349741.Amuc_1673	2.18e-269	736.0	COG1609@1|root,COG1609@2|Bacteria,46U1N@74201|Verrucomicrobia,2IUF7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	GntR,Peripla_BP_3
NEGHOLOK_01236	349741.Amuc_1678	4.46e-127	361.0	COG2087@1|root,COG2087@2|Bacteria	2|Bacteria	H	cobinamide kinase activity	cobU	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568	2.7.1.156,2.7.7.62,6.3.5.10	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R05225,R06558	RC00002,RC00010,RC00428,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iECIAI1_1343.ECIAI1_2074,iECSE_1348.ECSE_2277,iECW_1372.ECW_m2165,iETEC_1333.ETEC_2103,iEcE24377_1341.EcE24377A_2275,iEcSMS35_1347.EcSMS35_1131,iEcolC_1368.EcolC_1635,iLF82_1304.LF82_0337,iSDY_1059.SDY_2240,iWFL_1372.ECW_m2165	CobU
NEGHOLOK_01237	349741.Amuc_1679	1.65e-207	572.0	COG1082@1|root,COG1082@2|Bacteria	2|Bacteria	G	myo-inosose-2 dehydratase activity	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NEGHOLOK_01238	349741.Amuc_1680	1.62e-172	481.0	COG0368@1|root,COG0368@2|Bacteria	2|Bacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NEGHOLOK_01239	349741.Amuc_1681	4.02e-239	658.0	COG2038@1|root,COG2038@2|Bacteria	2|Bacteria	H	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NEGHOLOK_01240	349741.Amuc_1682	7.18e-234	644.0	COG1270@1|root,COG1270@2|Bacteria,46XN1@74201|Verrucomicrobia,2IW87@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
NEGHOLOK_01241	349741.Amuc_1683	0.0	1709.0	COG0079@1|root,COG1492@1|root,COG0079@2|Bacteria,COG1492@2|Bacteria,46UU7@74201|Verrucomicrobia,2IVRP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	-	-	-	-	-	-	-	-	-	-	GATase_3
NEGHOLOK_01242	349741.Amuc_1684	0.0	1370.0	COG4206@1|root,COG4206@2|Bacteria,46Z6S@74201|Verrucomicrobia,2IWPX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	TonB dependent receptor	-	-	-	ko:K02014	-	-	-	-	ko00000,ko02000	1.B.14	-	-	Plug,TonB_dep_Rec
NEGHOLOK_01243	349741.Amuc_1685	0.0	1374.0	COG4166@1|root,COG4166@2|Bacteria,46UFF@74201|Verrucomicrobia,2ITVT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K13893	ko02010,map02010	M00349	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.21,3.A.1.5.24	-	-	SBP_bac_5
NEGHOLOK_01244	349741.Amuc_1686	0.0	1652.0	COG1874@1|root,COG1874@2|Bacteria,46UVE@74201|Verrucomicrobia,2IU38@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 35	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_35
NEGHOLOK_01245	349741.Amuc_1687	6.65e-160	447.0	COG3637@1|root,COG3637@2|Bacteria	2|Bacteria	M	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety	-	-	-	ko:K16079	-	-	-	-	ko00000,ko02000	1.B.4.2.1	-	-	OMP_b-brl
NEGHOLOK_01246	349741.Amuc_1688	2.31e-313	854.0	COG0402@1|root,COG0402@2|Bacteria,46W01@74201|Verrucomicrobia,2IUMQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Amidohydrolase family	-	-	3.5.4.28,3.5.4.31	ko:K12960	ko00270,ko01100,map00270,map01100	-	R09660	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NEGHOLOK_01247	349741.Amuc_1689	0.0	906.0	COG1249@1|root,COG1249@2|Bacteria,46S7E@74201|Verrucomicrobia,2ITM3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
NEGHOLOK_01248	349741.Amuc_1690	5.53e-96	279.0	COG1669@1|root,COG1669@2|Bacteria,46XSM@74201|Verrucomicrobia,2IWH4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
NEGHOLOK_01249	349741.Amuc_1691	8.04e-60	185.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	3.4.11.5	ko:K01259	ko00330,map00330	-	R00135	-	ko00000,ko00001,ko01000,ko01002	-	-	-	NTP_transf_2
NEGHOLOK_01250	349741.Amuc_1692	5.45e-225	624.0	COG0508@1|root,COG0508@2|Bacteria,46SD3@74201|Verrucomicrobia,2ITTQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl
NEGHOLOK_01251	349741.Amuc_1693	0.0	1850.0	COG0567@1|root,COG0567@2|Bacteria,46S6G@74201|Verrucomicrobia,2ITMJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoglutarate dehydrogenase C-terminal	-	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
NEGHOLOK_01252	349741.Amuc_1694	1.21e-244	672.0	COG1294@1|root,COG1294@2|Bacteria,46U7S@74201|Verrucomicrobia,2IUU8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome bd terminal oxidase subunit II	-	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
NEGHOLOK_01253	349741.Amuc_1695	0.0	934.0	COG1271@1|root,COG1271@2|Bacteria,46UI0@74201|Verrucomicrobia,2IU3N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome bd terminal oxidase subunit I	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
NEGHOLOK_01254	349741.Amuc_1696	2.7e-113	324.0	COG1376@1|root,COG1376@2|Bacteria,46VRV@74201|Verrucomicrobia,2IUQ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_01255	349741.Amuc_1697	2.34e-107	309.0	COG0394@1|root,COG0394@2|Bacteria,46VB6@74201|Verrucomicrobia,2IUND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Low molecular weight phosphatase family	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NEGHOLOK_01256	349741.Amuc_1698	0.0	940.0	COG4252@1|root,COG4252@2|Bacteria,46Z6T@74201|Verrucomicrobia,2IUWF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Chase2 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01257	349741.Amuc_1699	2.51e-234	643.0	COG3178@1|root,COG3178@2|Bacteria,46SU7@74201|Verrucomicrobia,2IU89@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	2.7.1.221	ko:K07102	ko00520,ko01100,map00520,map01100	-	R08968,R11024	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
NEGHOLOK_01258	349741.Amuc_1700	1.25e-307	837.0	COG0133@1|root,COG0133@2|Bacteria,46XCI@74201|Verrucomicrobia,2IVFS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	-	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NEGHOLOK_01259	349741.Amuc_1701	1e-91	269.0	COG1846@1|root,COG1846@2|Bacteria,46VKR@74201|Verrucomicrobia,2IUD2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR
NEGHOLOK_01261	349741.Amuc_1703	2.46e-113	325.0	COG1528@1|root,COG1528@2|Bacteria,46WDU@74201|Verrucomicrobia,2IUMT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferritin-like domain	-	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
NEGHOLOK_01262	349741.Amuc_1704	0.0	949.0	2F6YF@1|root,33ZEH@2|Bacteria,46VWD@74201|Verrucomicrobia,2IU9D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01263	349741.Amuc_1705	5.44e-104	301.0	COG0251@1|root,COG0251@2|Bacteria,46VPS@74201|Verrucomicrobia,2IUFV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
NEGHOLOK_01265	349741.Amuc_1706	2.91e-114	329.0	COG2949@1|root,COG2949@2|Bacteria,46T0H@74201|Verrucomicrobia,2IUEI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DUF218 domain	-	-	-	ko:K03748	-	-	-	-	ko00000	-	-	-	DUF218
NEGHOLOK_01267	349741.Amuc_1707	3.45e-178	499.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
NEGHOLOK_01273	349741.Amuc_1710	0.0	1414.0	COG0514@1|root,COG0514@2|Bacteria,46U82@74201|Verrucomicrobia,2ITT4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RQC	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,Helicase_C,RQC,RecQ_Zn_bind
NEGHOLOK_01275	673860.AciM339_0375	0.00011	52.4	COG0582@1|root,arCOG01241@2157|Archaea,2XV3E@28890|Euryarchaeota,3F2X0@33867|unclassified Euryarchaeota	28890|Euryarchaeota	L	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules	xerA	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
NEGHOLOK_01278	1202962.KB907154_gene658	4.6e-05	51.2	2DM68@1|root,31W6X@2|Bacteria,1RK5E@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
NEGHOLOK_01286	349741.Amuc_2152	5.98e-66	232.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_01291	349741.Amuc_0065	5.46e-22	95.5	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,2ITRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	HMGL-like	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
NEGHOLOK_01292	349741.Amuc_0051	0.0	1143.0	COG0608@1|root,COG0608@2|Bacteria,46SNV@74201|Verrucomicrobia,2ITRD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DHHA1 domain	-	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NEGHOLOK_01293	349741.Amuc_0052	0.0	1907.0	COG3525@1|root,COG3525@2|Bacteria	2|Bacteria	G	beta-N-acetylhexosaminidase activity	hyl	GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564	2.3.1.48,3.2.1.169,3.2.1.35	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	M00076,M00077	R07824,R07825,R09672,R09673,R10905	RC00059,RC00397,RC00451,RC00746	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	GH84	-	F5_F8_type_C,Glyco_hydro_20b,NAGidase
NEGHOLOK_01294	349741.Amuc_0053	3.26e-226	623.0	COG0803@1|root,COG0803@2|Bacteria,46T95@74201|Verrucomicrobia,2IU7E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
NEGHOLOK_01295	349741.Amuc_0054	2.03e-100	291.0	29760@1|root,2ZUDX@2|Bacteria,46WRV@74201|Verrucomicrobia,2IWIT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01296	349741.Amuc_0055	2.15e-192	533.0	COG1121@1|root,COG1121@2|Bacteria,46T1P@74201|Verrucomicrobia,2ITV4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K09820	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC_tran
NEGHOLOK_01297	349741.Amuc_0056	3.84e-180	504.0	COG1108@1|root,COG1108@2|Bacteria,46V67@74201|Verrucomicrobia,2IUB1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	FecCD transport family	-	-	-	ko:K09819	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
NEGHOLOK_01298	349741.Amuc_0057	4.49e-125	356.0	COG3880@1|root,COG3880@2|Bacteria,46SXX@74201|Verrucomicrobia,2IUNQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	UvrB/uvrC motif	-	-	-	ko:K19411	-	-	-	-	ko00000	-	-	-	UVR
NEGHOLOK_01299	349741.Amuc_0058	8.21e-246	676.0	COG3869@1|root,COG3869@2|Bacteria,46S55@74201|Verrucomicrobia,2ITP7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ATP:guanido phosphotransferase, C-terminal catalytic domain	-	-	2.7.14.1	ko:K19405	-	-	R11090	RC00002,RC00203	ko00000,ko01000	-	-	-	ATP-gua_Ptrans
NEGHOLOK_01300	349741.Amuc_0059	0.0	1622.0	COG0542@1|root,COG0542@2|Bacteria,46SD6@74201|Verrucomicrobia,2ITPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
NEGHOLOK_01301	349741.Amuc_0060	0.0	1734.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.50	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	M00078	R07816	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	F5_F8_type_C,FIVAR,NAGLU,NAGLU_C,NAGLU_N
NEGHOLOK_01302	349741.Amuc_0063	6e-76	226.0	COG0607@1|root,COG0607@2|Bacteria,46X0H@74201|Verrucomicrobia,2IWDJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese Homology Domain	-	-	-	ko:K03972	-	-	-	-	ko00000	-	-	-	Rhodanese
NEGHOLOK_01303	349741.Amuc_0064	1.54e-203	563.0	COG0179@1|root,COG0179@2|Bacteria,46SDD@74201|Verrucomicrobia,2IUC8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Fumarylacetoacetate (FAA) hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
NEGHOLOK_01304	349741.Amuc_0065	0.0	1000.0	COG0119@1|root,COG0119@2|Bacteria,46TI3@74201|Verrucomicrobia,2ITRE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	HMGL-like	-	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
NEGHOLOK_01305	349741.Amuc_0066	1.28e-223	615.0	COG3391@1|root,COG3391@2|Bacteria	2|Bacteria	CO	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	SGL
NEGHOLOK_01306	349741.Amuc_0067	2.55e-94	276.0	COG1610@1|root,COG1610@2|Bacteria,46T4B@74201|Verrucomicrobia,2IUKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Yqey-like protein	-	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NEGHOLOK_01307	349741.Amuc_0068	6.13e-165	461.0	COG1211@1|root,COG1211@2|Bacteria,46T2A@74201|Verrucomicrobia,2IUDG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD
NEGHOLOK_01308	349741.Amuc_0069	2.63e-206	570.0	COG0451@1|root,COG0451@2|Bacteria,46SWG@74201|Verrucomicrobia,2IUD4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,SKI
NEGHOLOK_01309	349741.Amuc_0070	2.41e-232	639.0	COG0180@1|root,COG0180@2|Bacteria,46SA6@74201|Verrucomicrobia,2ITQN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
NEGHOLOK_01310	349741.Amuc_0071	1.56e-103	300.0	COG0589@1|root,COG0589@2|Bacteria,46T47@74201|Verrucomicrobia,2IV0V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
NEGHOLOK_01311	349741.Amuc_0072	1.45e-190	529.0	COG1692@1|root,COG1692@2|Bacteria,46SQ2@74201|Verrucomicrobia,2ITNG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	YmdB-like protein	-	-	-	ko:K09769	-	-	-	-	ko00000	-	-	-	YmdB
NEGHOLOK_01312	349741.Amuc_0073	5.86e-184	512.0	COG1179@1|root,COG1179@2|Bacteria,46THP@74201|Verrucomicrobia,2IU4H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	ThiF family	-	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NEGHOLOK_01313	349741.Amuc_0074	9.9e-121	344.0	296GV@1|root,2ZTSD@2|Bacteria,46WKD@74201|Verrucomicrobia,2IUJX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01315	349741.Amuc_0075	1.17e-231	639.0	COG0524@1|root,COG0524@2|Bacteria,46XQ2@74201|Verrucomicrobia,2IWCQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	pfkB family carbohydrate kinase	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NEGHOLOK_01316	349741.Amuc_0076	9.23e-124	352.0	COG1051@1|root,COG1051@2|Bacteria,46VKY@74201|Verrucomicrobia,2IUH7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NEGHOLOK_01317	349741.Amuc_0077	3.77e-289	789.0	COG0156@1|root,COG0156@2|Bacteria,46SSH@74201|Verrucomicrobia,2ITW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	kbl	-	2.3.1.29	ko:K00639	ko00260,map00260	-	R00371	RC00004,RC00394	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_01318	349741.Amuc_0078	0.0	1749.0	COG0515@1|root,COG1262@1|root,COG0515@2|Bacteria,COG1262@2|Bacteria,46TTW@74201|Verrucomicrobia,2IU0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PEGA,Pkinase
NEGHOLOK_01319	349741.Amuc_0079	1.06e-182	508.0	COG1192@1|root,COG1192@2|Bacteria,46SKQ@74201|Verrucomicrobia,2IU01@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NEGHOLOK_01320	349741.Amuc_0080	0.0	1807.0	COG0515@1|root,COG0790@1|root,COG0515@2|Bacteria,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
NEGHOLOK_01327	349741.Amuc_0085	1.04e-54	171.0	COG2104@1|root,COG2104@2|Bacteria	2|Bacteria	H	thiamine diphosphate biosynthetic process	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	iJN678.ycf40	ThiS
NEGHOLOK_01328	349741.Amuc_0086	0.0	1219.0	COG0323@1|root,COG0323@2|Bacteria,46SG5@74201|Verrucomicrobia,2ITR4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NEGHOLOK_01329	349741.Amuc_0088	0.0	1266.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	-	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	PglL_A,Wzy_C,Wzy_C_2
NEGHOLOK_01330	349741.Amuc_0089	8.67e-85	249.0	COG3189@1|root,COG3189@2|Bacteria,46WCK@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
NEGHOLOK_01332	349741.Amuc_0090	2.31e-232	639.0	COG0181@1|root,COG0181@2|Bacteria,46SWD@74201|Verrucomicrobia,2IU65@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Porphobilinogen deaminase, dipyromethane cofactor binding domain	-	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
NEGHOLOK_01333	349741.Amuc_0091	3.58e-239	658.0	COG0373@1|root,COG0373@2|Bacteria,46SMQ@74201|Verrucomicrobia,2IU0T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Glutamyl-tRNAGlu reductase, N-terminal domain	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,Shikimate_DH
NEGHOLOK_01334	349741.Amuc_0092	1.02e-178	498.0	COG4137@1|root,COG4137@2|Bacteria,46T0T@74201|Verrucomicrobia,2IUQ9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
NEGHOLOK_01335	349741.Amuc_0093	3.84e-189	525.0	COG1469@1|root,COG1469@2|Bacteria,46SIB@74201|Verrucomicrobia,2IU2Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Type I GTP cyclohydrolase folE2	folE2	-	3.5.4.16	ko:K09007	ko00790,ko01100,map00790,map01100	M00126	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GCHY-1
NEGHOLOK_01336	349741.Amuc_0094	4.52e-49	157.0	COG0238@1|root,COG0238@2|Bacteria,46TBC@74201|Verrucomicrobia,2IUU2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S18	-	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
NEGHOLOK_01337	349741.Amuc_0095	5.67e-33	114.0	COG0267@1|root,COG0267@2|Bacteria,46T91@74201|Verrucomicrobia,2IUS7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L33	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
NEGHOLOK_01338	349741.Amuc_0096	1.46e-118	345.0	COG1734@1|root,COG1734@2|Bacteria,46SVY@74201|Verrucomicrobia,2IUEF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
NEGHOLOK_01339	349741.Amuc_0097	5.9e-232	638.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia,2ITKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NEGHOLOK_01340	349741.Amuc_0098	1.65e-244	670.0	COG0144@1|root,COG0144@2|Bacteria	2|Bacteria	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176,2.1.1.178	ko:K03500,ko:K11392	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
NEGHOLOK_01341	349741.Amuc_0099	6.23e-123	350.0	COG0622@1|root,COG0622@2|Bacteria,46XK7@74201|Verrucomicrobia,2IW4A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NEGHOLOK_01342	349741.Amuc_0100	5.75e-98	284.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	nudI	-	3.6.1.55	ko:K03574,ko:K12944	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NEGHOLOK_01344	349741.Amuc_0102	4.09e-283	780.0	COG0845@1|root,COG0845@2|Bacteria,46U5P@74201|Verrucomicrobia,2IU9K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	HlyD_D23
NEGHOLOK_01345	349741.Amuc_0103	2.12e-162	455.0	COG1136@1|root,COG1136@2|Bacteria,46SI5@74201|Verrucomicrobia,2IUA4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NEGHOLOK_01346	349741.Amuc_0104	2.69e-310	847.0	COG0577@1|root,COG0577@2|Bacteria,46U7K@74201|Verrucomicrobia,2IU74@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
NEGHOLOK_01347	349741.Amuc_0105	8.19e-316	862.0	COG1538@1|root,COG1538@2|Bacteria,46US3@74201|Verrucomicrobia,2IUAN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Outer membrane efflux protein	-	-	-	-	-	-	-	-	-	-	-	-	OEP
NEGHOLOK_01348	349741.Amuc_0106	1.57e-284	776.0	COG1680@1|root,COG1680@2|Bacteria,46VB9@74201|Verrucomicrobia,2IWNM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NEGHOLOK_01349	349741.Amuc_0107	0.0	2007.0	COG0841@1|root,COG0841@2|Bacteria,46SDN@74201|Verrucomicrobia,2IWND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NEGHOLOK_01350	349741.Amuc_0108	8.54e-283	778.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mtrC	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NEGHOLOK_01351	349741.Amuc_0109	1.02e-94	276.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NEGHOLOK_01352	349741.Amuc_0110	2.51e-167	467.0	COG1720@1|root,COG1720@2|Bacteria,46VWT@74201|Verrucomicrobia,2IU7Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NEGHOLOK_01353	349741.Amuc_0111	1.37e-306	835.0	COG0044@1|root,COG0044@2|Bacteria,46S78@74201|Verrucomicrobia,2ITJU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Dihydro-orotase-like	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NEGHOLOK_01354	349741.Amuc_0112	1.55e-222	613.0	COG0540@1|root,COG0540@2|Bacteria,46S9E@74201|Verrucomicrobia,2ITMZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NEGHOLOK_01355	349741.Amuc_0113	1.15e-122	350.0	COG2065@1|root,COG2065@2|Bacteria,46VY6@74201|Verrucomicrobia,2IUM6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Phosphoribosyl transferase domain	-	-	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
NEGHOLOK_01356	349741.Amuc_0114	3.73e-90	264.0	COG0041@1|root,COG0041@2|Bacteria,46SRV@74201|Verrucomicrobia,2IUG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AIR carboxylase	-	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NEGHOLOK_01358	349741.Amuc_0116	0.0	1050.0	COG2509@1|root,COG2509@2|Bacteria,46UJ1@74201|Verrucomicrobia,2ITVH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	5-formyltetrahydrofolate cyclo-ligase activity	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	-
NEGHOLOK_01359	349741.Amuc_0117	6.45e-268	731.0	COG2957@1|root,COG2957@2|Bacteria,46SAM@74201|Verrucomicrobia,2IU1P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Porphyromonas-type peptidyl-arginine deiminase	-	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
NEGHOLOK_01360	349741.Amuc_0118	2.11e-89	262.0	2E5IJ@1|root,3309Y@2|Bacteria,46YZF@74201|Verrucomicrobia,2IUSS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01361	349741.Amuc_0119	0.0	884.0	COG0750@1|root,COG0750@2|Bacteria	2|Bacteria	M	metalloendopeptidase activity	rseP	-	3.4.21.116	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50,Peptidase_S55
NEGHOLOK_01362	349741.Amuc_0120	1.7e-297	813.0	COG0628@1|root,COG0628@2|Bacteria,46VTV@74201|Verrucomicrobia,2ITP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NEGHOLOK_01363	349741.Amuc_0121	0.0	1071.0	COG3119@1|root,COG3119@2|Bacteria,46S9C@74201|Verrucomicrobia,2ITNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	DUF4994,Sulfatase
NEGHOLOK_01365	909663.KI867150_gene300	1.13e-111	350.0	COG0370@1|root,COG0370@2|Bacteria,1MUZC@1224|Proteobacteria,42MCY@68525|delta/epsilon subdivisions,2WIWJ@28221|Deltaproteobacteria,2MR4V@213462|Syntrophobacterales	28221|Deltaproteobacteria	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NEGHOLOK_01366	349741.Amuc_0124	6.46e-312	849.0	COG5301@1|root,COG5301@2|Bacteria,46UXN@74201|Verrucomicrobia,2IW6U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	cellulose 1,4-beta-cellobiosidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01367	349741.Amuc_0125	1.91e-186	517.0	COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_01369	349741.Amuc_0127	1.83e-74	224.0	2A0RX@1|root,30MWM@2|Bacteria,46XN7@74201|Verrucomicrobia,2IW8P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01370	349741.Amuc_0128	0.0	1361.0	COG0188@1|root,COG0188@2|Bacteria,46TWK@74201|Verrucomicrobia,2ITPU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA Topoisomerase IV	-	-	-	ko:K02621	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_topoisoIV
NEGHOLOK_01372	349741.Amuc_0129	1.29e-132	376.0	COG3926@1|root,COG3926@2|Bacteria	2|Bacteria	S	Glycosyl hydrolase 108	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_108,PG_binding_3,Peptidase_M15_4
NEGHOLOK_01375	349741.Amuc_0133	1.24e-200	556.0	COG1475@1|root,COG1475@2|Bacteria,46SQ8@74201|Verrucomicrobia,2IU4T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NEGHOLOK_01376	349741.Amuc_0134	5.07e-235	645.0	COG2234@1|root,COG2234@2|Bacteria,46VSB@74201|Verrucomicrobia,2IVUM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
NEGHOLOK_01377	349741.Amuc_0135	0.0	1304.0	COG1361@1|root,COG1361@2|Bacteria,46TNR@74201|Verrucomicrobia,2IWKJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
NEGHOLOK_01378	349741.Amuc_0136	0.0	1430.0	COG2304@1|root,COG2373@1|root,COG5426@1|root,COG2304@2|Bacteria,COG2373@2|Bacteria,COG5426@2|Bacteria,46TJC@74201|Verrucomicrobia,2IWMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Large extracellular alpha-helical protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01381	349741.Amuc_0139	1.11e-235	648.0	COG0385@1|root,COG0385@2|Bacteria,46V81@74201|Verrucomicrobia,2IUMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SBF-like CPA transporter family (DUF4137)	-	-	-	ko:K14347	-	-	-	-	ko00000,ko02000,ko04147	2.A.93.1	-	-	SBF_like
NEGHOLOK_01382	349741.Amuc_0140	4.56e-273	748.0	COG0162@1|root,COG0162@2|Bacteria,46S76@74201|Verrucomicrobia,2IWM1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (W and Y)	-	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_1b
NEGHOLOK_01384	349741.Amuc_0142	1.01e-84	249.0	COG3169@1|root,COG3169@2|Bacteria,46T5W@74201|Verrucomicrobia,2IUI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative member of DMT superfamily (DUF486)	-	-	-	ko:K09922	-	-	-	-	ko00000	-	-	-	DMT_6
NEGHOLOK_01385	349741.Amuc_0143	1.87e-212	588.0	COG1173@1|root,COG1173@2|Bacteria,46SN0@74201|Verrucomicrobia,2ITN8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NEGHOLOK_01386	349741.Amuc_0144	1.6e-217	600.0	COG0601@1|root,COG0601@2|Bacteria,46SJN@74201|Verrucomicrobia,2ITJ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NEGHOLOK_01387	349741.Amuc_0145	0.0	1275.0	COG4166@1|root,COG4166@2|Bacteria,46SBG@74201|Verrucomicrobia,2ITVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
NEGHOLOK_01388	349741.Amuc_0146	0.0	1462.0	COG3669@1|root,COG3669@2|Bacteria	2|Bacteria	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
NEGHOLOK_01389	349741.Amuc_0147	1.53e-219	607.0	COG2143@1|root,COG2143@2|Bacteria,46Z6E@74201|Verrucomicrobia,2IW7D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_7
NEGHOLOK_01390	349741.Amuc_0148	4.57e-311	845.0	COG1748@1|root,COG1748@2|Bacteria,46U4S@74201|Verrucomicrobia,2ITQI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Saccharopine dehydrogenase C-terminal domain	-	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NEGHOLOK_01391	349741.Amuc_0149	3.02e-236	649.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	ko:K01128	-	-	-	-	ko00000,ko01000	-	-	-	Metallophos
NEGHOLOK_01394	349741.Amuc_0152	1.81e-310	850.0	COG0206@1|root,COG0206@2|Bacteria,46UWD@74201|Verrucomicrobia,2ITWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Tubulin/FtsZ family, GTPase domain	-	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NEGHOLOK_01395	349741.Amuc_0153	3.38e-294	802.0	COG0849@1|root,COG0849@2|Bacteria,46SQI@74201|Verrucomicrobia,2ITMT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring	ftsA	-	-	ko:K03590	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036,ko04812	-	-	-	FtsA,SHS2_FTSA
NEGHOLOK_01396	349741.Amuc_0154	1.72e-147	414.0	COG0791@1|root,COG0791@2|Bacteria,46VUJ@74201|Verrucomicrobia,2IUPC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01397	349741.Amuc_0155	0.0	1278.0	COG1109@1|root,COG1109@2|Bacteria,46SB1@74201|Verrucomicrobia,2ITGG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00549	R00959,R01057,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NEGHOLOK_01398	349741.Amuc_0156	0.0	1123.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,2ITX3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
NEGHOLOK_01399	349741.Amuc_0157	0.0	1171.0	COG1132@1|root,COG1132@2|Bacteria,46S6K@74201|Verrucomicrobia,2ITX3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC transporter transmembrane region	-	-	-	ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106	-	-	ABC_membrane,ABC_tran
NEGHOLOK_01400	349741.Amuc_0158	0.0	918.0	COG0388@1|root,COG0388@2|Bacteria,46U7Q@74201|Verrucomicrobia,2ITXJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	NAD synthase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase,NAD_synthase
NEGHOLOK_01401	349741.Amuc_0159	1.49e-167	470.0	COG0767@1|root,COG0767@2|Bacteria,46VY4@74201|Verrucomicrobia,2IWMP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	Permease MlaE	-	-	-	ko:K02066	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaE
NEGHOLOK_01402	349741.Amuc_0160	1.75e-189	526.0	COG1127@1|root,COG1127@2|Bacteria,46SRC@74201|Verrucomicrobia,2ITMB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	ATPases associated with a variety of cellular activities	-	-	-	ko:K02065	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	ABC_tran
NEGHOLOK_01403	349741.Amuc_0161	1.9e-231	638.0	COG1463@1|root,COG1463@2|Bacteria,46T81@74201|Verrucomicrobia,2IUM4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	MlaD protein	-	-	-	ko:K02067	ko02010,map02010	M00210,M00669,M00670	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.27	-	-	MlaD
NEGHOLOK_01404	349741.Amuc_0162	2.69e-38	131.0	COG4575@1|root,COG4575@2|Bacteria	2|Bacteria	T	ribosome binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF883
NEGHOLOK_01407	349741.Amuc_0165	5.1e-265	725.0	COG2805@1|root,COG2805@2|Bacteria,46UF2@74201|Verrucomicrobia,2ITJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
NEGHOLOK_01408	349741.Amuc_0166	3.71e-260	713.0	COG2805@1|root,COG2805@2|Bacteria,46SY2@74201|Verrucomicrobia,2ITP5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type II/IV secretion system protein	-	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
NEGHOLOK_01409	349741.Amuc_0167	3.36e-248	682.0	COG0760@1|root,COG0760@2|Bacteria	2|Bacteria	O	peptidyl-prolyl cis-trans isomerase activity	ppiD	-	5.2.1.8	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_3
NEGHOLOK_01411	349741.Amuc_0168	0.0	975.0	29ZA9@1|root,30M8M@2|Bacteria,46XI8@74201|Verrucomicrobia,2IVZI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01412	349741.Amuc_0169	2.4e-180	501.0	COG1212@1|root,COG1212@2|Bacteria,46SS4@74201|Verrucomicrobia,2IU4F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria	kdsB	-	2.7.7.38	ko:K00979	ko00540,ko01100,map00540,map01100	M00063	R03351,R11396	RC00152,RC00910	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3
NEGHOLOK_01413	349741.Amuc_0170	0.0	1068.0	COG0504@1|root,COG0504@2|Bacteria,46S8K@74201|Verrucomicrobia,2ITX8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
NEGHOLOK_01414	349741.Amuc_0171	0.0	1009.0	COG0591@1|root,COG0591@2|Bacteria,46SPP@74201|Verrucomicrobia,2ITZE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Sodium:solute symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SSF
NEGHOLOK_01415	349741.Amuc_2143	7.07e-249	683.0	COG4763@1|root,COG4763@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NEGHOLOK_01416	349741.Amuc_2142	0.0	989.0	COG0342@1|root,COG0342@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
NEGHOLOK_01420	349741.Amuc_2138	5.93e-261	715.0	COG0079@1|root,COG0079@2|Bacteria,46SFP@74201|Verrucomicrobia,2ITIN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_01421	349741.Amuc_2137	8.43e-155	434.0	COG0778@1|root,COG0778@2|Bacteria,46V9P@74201|Verrucomicrobia,2IU8H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	1.5.1.34	ko:K10679	ko00633,ko01120,map00633,map01120	-	R08014,R08017,R08042	RC00250	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
NEGHOLOK_01422	349741.Amuc_2136	0.0	1538.0	COG3525@1|root,COG3525@2|Bacteria,46XE0@74201|Verrucomicrobia,2IVMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 20, domain 2	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_01423	349741.Amuc_2135	4.16e-178	495.0	COG0791@1|root,COG0791@2|Bacteria,46VPQ@74201|Verrucomicrobia,2IUIV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NLP P60 protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01424	349741.Amuc_2134	1.37e-86	255.0	COG3296@1|root,COG3296@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4870)	-	-	-	ko:K09940	-	-	-	-	ko00000	-	-	-	DUF4870
NEGHOLOK_01426	349741.Amuc_2132	8.53e-76	226.0	COG0375@1|root,COG0375@2|Bacteria,46WGA@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Hydrogenase/urease nickel incorporation, metallochaperone, hypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
NEGHOLOK_01427	349741.Amuc_2131	3.4e-126	359.0	COG0680@1|root,COG0680@2|Bacteria,46WHX@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
NEGHOLOK_01428	349741.Amuc_2130	9.22e-290	790.0	COG1969@1|root,COG1969@2|Bacteria,46WHN@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Prokaryotic cytochrome b561	hyaC	-	-	ko:K03620	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
NEGHOLOK_01429	349741.Amuc_2129	0.0	1217.0	COG0374@1|root,COG0374@2|Bacteria,46UEU@74201|Verrucomicrobia	74201|Verrucomicrobia	C	Nickel-dependent hydrogenase	-	-	1.12.99.6	ko:K06281	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFeSe_Hases
NEGHOLOK_01430	349741.Amuc_2128	6.94e-298	811.0	COG1740@1|root,COG1740@2|Bacteria,46UW4@74201|Verrucomicrobia	74201|Verrucomicrobia	C	NiFe/NiFeSe hydrogenase small subunit C-terminal	-	-	1.12.99.6	ko:K06282	ko00633,ko01120,map00633,map01120	-	R08034	RC00250	ko00000,ko00001,ko01000	-	-	-	NiFe_hyd_SSU_C,Oxidored_q6
NEGHOLOK_01431	349741.Amuc_2127	0.0	994.0	COG3659@1|root,COG3659@2|Bacteria	2|Bacteria	M	wide pore channel activity	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB
NEGHOLOK_01433	349741.Amuc_2125	0.0	862.0	COG0104@1|root,COG0104@2|Bacteria,46TDF@74201|Verrucomicrobia,2ITUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NEGHOLOK_01435	349741.Amuc_2124	0.0	926.0	COG1057@1|root,COG1057@2|Bacteria,46S7M@74201|Verrucomicrobia,2ITSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01436	349741.Amuc_2123	0.0	892.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	3.4.24.3	ko:K01387	-	-	-	-	ko00000,ko01000,ko01002,ko02042	-	-	-	DEAD,Helicase_C,PKD,PPC,Peptidase_M9,Peptidase_M9_N
NEGHOLOK_01437	349741.Amuc_2122	0.0	1654.0	COG0744@1|root,COG0744@2|Bacteria,46TMG@74201|Verrucomicrobia,2ITVY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
NEGHOLOK_01438	349741.Amuc_2121	2.63e-135	382.0	COG0193@1|root,COG0193@2|Bacteria,46T09@74201|Verrucomicrobia,2IUCW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptidyl-tRNA hydrolase	-	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NEGHOLOK_01439	349741.Amuc_2120	3.22e-215	594.0	COG1721@1|root,COG1721@2|Bacteria,46UUS@74201|Verrucomicrobia,2ITRG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NEGHOLOK_01440	349741.Amuc_2119	3.82e-231	637.0	COG0714@1|root,COG0714@2|Bacteria,46TCY@74201|Verrucomicrobia,2ITSU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NEGHOLOK_01441	349741.Amuc_2118	4.08e-215	592.0	COG0388@1|root,COG0388@2|Bacteria,46S7B@74201|Verrucomicrobia,2ITNA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Carbon-nitrogen hydrolase	-	-	3.5.1.53	ko:K12251	ko00330,ko01100,map00330,map01100	-	R01152	RC00096	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
NEGHOLOK_01443	349741.Amuc_2116	5.79e-274	748.0	COG1063@1|root,COG1063@2|Bacteria,46USX@74201|Verrucomicrobia,2IWQ1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NEGHOLOK_01444	349741.Amuc_2115	2.56e-309	846.0	COG0172@1|root,COG0172@2|Bacteria,46S70@74201|Verrucomicrobia,2ITV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Seryl-tRNA synthetase N-terminal domain	-	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NEGHOLOK_01446	349741.Amuc_2113	5.7e-241	664.0	COG0635@1|root,COG0635@2|Bacteria,46STN@74201|Verrucomicrobia,2ITVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NEGHOLOK_01447	349741.Amuc_2112	0.0	1836.0	COG0265@1|root,COG0265@2|Bacteria	2|Bacteria	O	serine-type endopeptidase activity	yidC	-	-	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,DUF4124,PDZ_2,Peptidase_C11,SLH,TPM_phosphatase,TPR_11,Trypsin_2,YidC_periplas
NEGHOLOK_01448	349741.Amuc_2111	1.07e-157	441.0	COG1376@1|root,COG1376@2|Bacteria,46VEG@74201|Verrucomicrobia,2IUCV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_01449	349741.Amuc_2110	2.76e-129	367.0	COG0461@1|root,COG0461@2|Bacteria,46YZ3@74201|Verrucomicrobia,2IU4N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NEGHOLOK_01450	349741.Amuc_2109	3.55e-257	704.0	COG1472@1|root,COG1472@2|Bacteria,46S5G@74201|Verrucomicrobia,2ITMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
NEGHOLOK_01451	349741.Amuc_2108	5.92e-231	634.0	COG2273@1|root,COG2273@2|Bacteria	2|Bacteria	G	xyloglucan:xyloglucosyl transferase activity	exsH	-	3.2.1.178,3.2.1.18,3.2.1.52	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R04018,R06004,R11316	RC00028,RC00049,RC00077	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	-	GH16,GH20,GH33	-	CBM_4_9,Glyco_hydro_16
NEGHOLOK_01452	349741.Amuc_2107	0.0	2948.0	COG0265@1|root,COG1657@1|root,COG0265@2|Bacteria,COG1657@2|Bacteria	2|Bacteria	I	PFAM Prenyltransferase squalene oxidase	-	-	-	ko:K06889,ko:K09914	-	-	-	-	ko00000	-	-	-	DUF4159,Flg_new,Trypsin_2
NEGHOLOK_01453	349741.Amuc_2106	9.53e-317	863.0	COG0281@1|root,COG0281@2|Bacteria,46UWJ@74201|Verrucomicrobia,2IWHX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Malic enzyme, NAD binding domain	-	-	1.1.1.40	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	M00169,M00172	R00216	RC00105	ko00000,ko00001,ko00002,ko01000	-	-	-	Malic_M,malic
NEGHOLOK_01455	349741.Amuc_2104	0.0	1043.0	COG1165@1|root,COG1165@2|Bacteria,46URH@74201|Verrucomicrobia,2ITVW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	-	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_N
NEGHOLOK_01456	349741.Amuc_2103	0.0	1110.0	COG0143@1|root,COG0143@2|Bacteria,46SCQ@74201|Verrucomicrobia,2ITVG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (C) catalytic domain	-	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g
NEGHOLOK_01457	349741.Amuc_2102	1.06e-300	818.0	COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,2ITQB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_01458	349741.Amuc_2101	1.19e-92	271.0	COG4154@1|root,COG4154@2|Bacteria,46XH1@74201|Verrucomicrobia,2IVWI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	RbsD / FucU transport protein family	-	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
NEGHOLOK_01459	349741.Amuc_2100	3.57e-283	773.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase,HMG-CoA_red
NEGHOLOK_01461	349741.Amuc_2098	0.0	1328.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_01462	349741.Amuc_2097	3.66e-229	632.0	COG0778@1|root,COG0778@2|Bacteria,46XN9@74201|Verrucomicrobia,2IW8U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NEGHOLOK_01463	349741.Amuc_2096	0.0	905.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	MatE,Polysacc_synt
NEGHOLOK_01464	349741.Amuc_2095	8.91e-123	367.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
NEGHOLOK_01465	1158294.JOMI01000009_gene1050	1.55e-39	149.0	COG0463@1|root,COG0463@2|Bacteria,4NS35@976|Bacteroidetes,2FT3C@200643|Bacteroidia	976|Bacteroidetes	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01466	349741.Amuc_2094	6.44e-239	657.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,PS_pyruv_trans
NEGHOLOK_01467	349741.Amuc_2093	1.42e-209	578.0	COG0463@1|root,COG0463@2|Bacteria,46U7T@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01468	349741.Amuc_2092	5.38e-113	325.0	COG0110@1|root,COG0110@2|Bacteria,46VHY@74201|Verrucomicrobia,2IW1D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	maltose O-acetyltransferase activity	-	-	-	ko:K03818	-	-	-	-	ko00000,ko01000	-	-	-	-
NEGHOLOK_01469	349741.Amuc_2091	0.0	1014.0	2BTJC@1|root,32NRX@2|Bacteria,46XRE@74201|Verrucomicrobia,2IWF2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01470	349741.Amuc_2090	3.29e-279	763.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lsgC	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
NEGHOLOK_01471	349741.Amuc_2089	5.46e-281	767.0	COG0438@1|root,COG0438@2|Bacteria,46VET@74201|Verrucomicrobia,2IUKI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_4_4,Glycos_transf_1
NEGHOLOK_01472	349741.Amuc_2088	8.31e-253	693.0	COG0438@1|root,COG0438@2|Bacteria,46XJ3@74201|Verrucomicrobia,2IW1V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_1
NEGHOLOK_01473	349741.Amuc_2087	1.52e-201	557.0	2E5B4@1|root,33038@2|Bacteria,46WQT@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01474	349741.Amuc_2086	3.73e-263	722.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
NEGHOLOK_01475	349741.Amuc_2085	3.46e-241	661.0	2E5IX@1|root,330A8@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01476	349741.Amuc_2084	6.05e-295	803.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	gtf1	GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016758	2.4.1.52	ko:K00712	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_A_1,Glycos_transf_1
NEGHOLOK_01477	349741.Amuc_2083	2.84e-285	779.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lsgC	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
NEGHOLOK_01478	349741.Amuc_2082	1.47e-292	796.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lsgC	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Glycos_transf_2
NEGHOLOK_01479	349741.Amuc_2081	1.2e-189	526.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wbyL	-	-	ko:K13002	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NEGHOLOK_01480	349741.Amuc_2080	6.88e-176	493.0	COG2148@1|root,COG2148@2|Bacteria,46UQE@74201|Verrucomicrobia,2IUN5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NEGHOLOK_01481	349741.Amuc_2079	9.48e-165	460.0	COG4464@1|root,COG4464@2|Bacteria	2|Bacteria	GM	protein tyrosine phosphatase activity	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NEGHOLOK_01482	349741.Amuc_2078	0.0	1473.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,46V4D@74201|Verrucomicrobia	74201|Verrucomicrobia	DM	PFAM lipopolysaccharide biosynthesis protein	gumC	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
NEGHOLOK_01483	349741.Amuc_2077	5.68e-180	503.0	COG1596@1|root,COG1596@2|Bacteria	2|Bacteria	M	polysaccharide export	-	-	-	ko:K01991	ko02026,map02026	-	-	-	ko00000,ko00001,ko02000	1.B.18	-	-	Poly_export,SLBB
NEGHOLOK_01498	552398.HMPREF0866_02218	1.4e-09	67.0	COG4388@1|root,COG4388@2|Bacteria,1TRUA@1239|Firmicutes,24BB0@186801|Clostridia,3WNA2@541000|Ruminococcaceae	186801|Clostridia	S	Mu-like prophage I protein	-	-	-	-	-	-	-	-	-	-	-	-	Mu-like_Pro
NEGHOLOK_01501	278957.ABEA03000094_gene4689	1.38e-76	243.0	COG4373@1|root,COG4373@2|Bacteria,46UAU@74201|Verrucomicrobia,3K9CW@414999|Opitutae	414999|Opitutae	S	Mu-like prophage FluMu protein gp28	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01505	1196029.ALIM01000014_gene3381	1.98e-12	72.8	COG1876@1|root,COG3409@1|root,COG1876@2|Bacteria,COG3409@2|Bacteria,1VC9C@1239|Firmicutes,4HNA4@91061|Bacilli,1ZGE1@1386|Bacillus	91061|Bacilli	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	PG_binding_1,Peptidase_M15_4
NEGHOLOK_01521	1302863.I872_10325	0.000705	42.7	COG3620@1|root,COG3620@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4870,HTH_3,HTH_31
NEGHOLOK_01522	522373.Smlt0325	8.31e-62	200.0	COG0863@1|root,COG2189@1|root,COG0863@2|Bacteria,COG2189@2|Bacteria,1R7RR@1224|Proteobacteria,1S34G@1236|Gammaproteobacteria,1X6DS@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
NEGHOLOK_01523	349741.Amuc_2076	0.0	1561.0	COG1674@1|root,COG3170@1|root,COG1674@2|Bacteria,COG3170@2|Bacteria,46SCV@74201|Verrucomicrobia,2ITHR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NEGHOLOK_01525	349741.Amuc_2074	7.6e-145	407.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NEGHOLOK_01526	349741.Amuc_2072	1.08e-136	386.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NEGHOLOK_01527	349741.Amuc_2071	0.0	1655.0	COG0755@1|root,COG1333@1|root,COG3159@1|root,COG0755@2|Bacteria,COG1333@2|Bacteria,COG3159@2|Bacteria,46VBM@74201|Verrucomicrobia,2IU24@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Cytochrome C assembly protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_C_asm
NEGHOLOK_01529	349741.Amuc_2070	0.0	1513.0	COG0753@1|root,COG0753@2|Bacteria,46TCG@74201|Verrucomicrobia,2IUWP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Catalase	-	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
NEGHOLOK_01530	1123070.KB899248_gene24	1.17e-44	150.0	COG1847@1|root,COG1847@2|Bacteria,46VYD@74201|Verrucomicrobia,2IUMF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	R3H domain	-	-	-	-	-	-	-	-	-	-	-	-	R3H
NEGHOLOK_01532	349741.Amuc_2066	0.0	2326.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,46SAP@74201|Verrucomicrobia,2ITGA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CE	Proline dehydrogenase	-	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
NEGHOLOK_01533	349741.Amuc_2065	1.79e-282	771.0	COG3274@1|root,COG3274@2|Bacteria	2|Bacteria	S	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_01536	349741.Amuc_2063	1.71e-64	196.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NEGHOLOK_01537	349741.Amuc_2062	9.88e-145	408.0	2ECX1@1|root,336U7@2|Bacteria,46WXQ@74201|Verrucomicrobia,2IWIP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01539	349741.Amuc_2060	0.0	1095.0	28HPK@1|root,2Z7XJ@2|Bacteria,46VI6@74201|Verrucomicrobia,2IVHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
NEGHOLOK_01541	349741.Amuc_2058	1.56e-182	511.0	2B73I@1|root,3204H@2|Bacteria,46WXA@74201|Verrucomicrobia,2IWC2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01543	1141662.OOA_13497	1.46e-72	242.0	COG4928@1|root,COG4928@2|Bacteria,1MWRP@1224|Proteobacteria,1RZUM@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	PFAM KAP P-loop domain protein	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase
NEGHOLOK_01551	349741.Amuc_2157	6.52e-139	392.0	COG0377@1|root,COG0377@2|Bacteria,46SMM@74201|Verrucomicrobia,2ITJ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
NEGHOLOK_01552	349741.Amuc_2158	2.1e-140	396.0	COG0852@1|root,COG0852@2|Bacteria,46STM@74201|Verrucomicrobia,2IU60@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoC	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
NEGHOLOK_01553	349741.Amuc_2159	1.14e-166	468.0	2CXV0@1|root,32T2Q@2|Bacteria,46XHA@74201|Verrucomicrobia,2IVX5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01554	349741.Amuc_2160	1.27e-70	212.0	COG0571@1|root,COG0571@2|Bacteria,46WCW@74201|Verrucomicrobia,2IUR4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	ribonuclease III activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01555	349741.Amuc_2161	4.14e-279	762.0	COG0318@1|root,COG0318@2|Bacteria,46XUP@74201|Verrucomicrobia,2IUC3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding
NEGHOLOK_01557	349741.Amuc_2163	0.0	1738.0	COG0790@1|root,COG0790@2|Bacteria	2|Bacteria	S	beta-lactamase activity	-	-	-	ko:K07126,ko:K13582	ko04112,map04112	-	-	-	ko00000,ko00001	-	-	-	MORN_2,Peptidase_C14,Pkinase,Sel1
NEGHOLOK_01558	349741.Amuc_2164	0.0	2418.0	COG3325@1|root,COG3325@2|Bacteria,46X1V@74201|Verrucomicrobia,2IUY1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
NEGHOLOK_01559	349741.Amuc_0952	2.51e-06	55.5	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01560	349741.Amuc_2166	0.0	899.0	COG0673@1|root,COG0673@2|Bacteria,46W0X@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NEGHOLOK_01561	349741.Amuc_2167	0.0	1432.0	COG0339@1|root,COG0339@2|Bacteria,46TWS@74201|Verrucomicrobia,2ITQT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase family M3	-	-	3.4.24.70	ko:K01414	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3
NEGHOLOK_01564	349741.Amuc_2169	0.0	1176.0	COG0018@1|root,COG0018@2|Bacteria,46SH6@74201|Verrucomicrobia,2ITX2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NEGHOLOK_01566	349741.Amuc_2171	1.87e-215	593.0	COG1594@1|root,COG1594@2|Bacteria,46XN4@74201|Verrucomicrobia,2IW8B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01567	349741.Amuc_2172	1.73e-123	351.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	paiA	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NEGHOLOK_01568	349741.Amuc_2173	9.41e-233	641.0	COG0526@1|root,COG0526@2|Bacteria,46TGF@74201|Verrucomicrobia,2IW4P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
NEGHOLOK_01569	349741.Amuc_2174	4.73e-85	250.0	COG3070@1|root,COG3070@2|Bacteria	2|Bacteria	K	positive regulation of type IV pilus biogenesis	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_N
NEGHOLOK_01570	349741.Amuc_2175	7.41e-177	493.0	COG3896@1|root,COG3896@2|Bacteria	2|Bacteria	V	Chloramphenicol phosphotransferase-like protein	-	-	6.3.5.11,6.3.5.9	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	br01600,ko00000,ko00001,ko01000,ko01504	-	-	-	CPT,CbiA,GATase_3
NEGHOLOK_01572	349741.Amuc_2176	0.0	3669.0	COG0178@1|root,COG0178@2|Bacteria,46SAF@74201|Verrucomicrobia,2ITHY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	-
NEGHOLOK_01573	349741.Amuc_2177	0.0	2137.0	COG0653@1|root,COG0653@2|Bacteria,46SJC@74201|Verrucomicrobia,2ITJP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NEGHOLOK_01574	349741.Amuc_2178	3.58e-251	690.0	COG0548@1|root,COG1246@1|root,COG0548@2|Bacteria,COG1246@2|Bacteria,46SH2@74201|Verrucomicrobia,2IU99@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Acetyltransferase (GNAT) family	-	-	2.3.1.1	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,Acetyltransf_1
NEGHOLOK_01576	484770.UFO1_2464	2.82e-42	167.0	COG5525@1|root,COG5525@2|Bacteria,1TQBY@1239|Firmicutes,4H6KC@909932|Negativicutes	909932|Negativicutes	S	Phage terminase large subunit (GpA)	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_GpA
NEGHOLOK_01579	1197719.A464_2019	1.05e-19	97.1	COG0740@1|root,COG0740@2|Bacteria,1MUQ9@1224|Proteobacteria,1RRQA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	OU	Belongs to the peptidase S14 family	-	-	-	-	-	-	-	-	-	-	-	-	CLP_protease
NEGHOLOK_01596	1085623.GNIT_0606	5.83e-30	119.0	COG3409@1|root,COG3409@2|Bacteria,1RAFU@1224|Proteobacteria,1S7NF@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01597	1008459.TASI_0157	1.09e-12	67.4	COG2944@1|root,COG2944@2|Bacteria,1MZGM@1224|Proteobacteria,2VUVU@28216|Betaproteobacteria,3T9FI@506|Alcaligenaceae	28216|Betaproteobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_31
NEGHOLOK_01599	945543.VIBR0546_01476	0.000452	50.1	2DPCB@1|root,331HJ@2|Bacteria,1NED4@1224|Proteobacteria,1SGZF@1236|Gammaproteobacteria,1XYAZ@135623|Vibrionales	135623|Vibrionales	S	Putative phage abortive infection protein	-	-	-	-	-	-	-	-	-	-	-	-	putAbiC
NEGHOLOK_01609	2754.EH55_13135	9.34e-11	66.2	2CWYZ@1|root,32T0P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01611	742738.HMPREF9460_01357	8.13e-06	56.6	COG3598@1|root,COG3598@2|Bacteria,1TP5Q@1239|Firmicutes,24A4I@186801|Clostridia,26AUC@186813|unclassified Clostridiales	186801|Clostridia	L	Primase C terminal 2 (PriCT-2)	-	-	-	ko:K07505	-	-	-	-	ko00000	-	-	-	AAA_25,PriCT_2
NEGHOLOK_01612	1396418.BATQ01000127_gene2532	2.73e-22	108.0	COG4643@1|root,COG4643@2|Bacteria	2|Bacteria	P	DNA integration	traC	-	-	-	-	-	-	-	-	-	-	-	DUF3987,DUF3991,Toprim_2,Toprim_3
NEGHOLOK_01613	349741.Amuc_0600	4.06e-41	158.0	COG4974@1|root,COG4974@2|Bacteria,46Z6H@74201|Verrucomicrobia,2IWPR@203494|Verrucomicrobiae	2|Bacteria	L	Belongs to the 'phage' integrase family	xerD1	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NEGHOLOK_01615	349741.Amuc_0001	2.38e-133	377.0	COG0494@1|root,COG0494@2|Bacteria	2|Bacteria	L	nUDIX hydrolase	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NEGHOLOK_01616	349741.Amuc_0002	0.0	890.0	COG0593@1|root,COG0593@2|Bacteria,46S6H@74201|Verrucomicrobia,2ITNP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NEGHOLOK_01617	349741.Amuc_0003	1.09e-223	616.0	COG1131@1|root,COG1131@2|Bacteria,46UAZ@74201|Verrucomicrobia,2ITJ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NEGHOLOK_01618	349741.Amuc_0004	2.49e-183	510.0	COG1277@1|root,COG1277@2|Bacteria,46T0W@74201|Verrucomicrobia,2IU5C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
NEGHOLOK_01619	349741.Amuc_0005	0.0	1014.0	COG3225@1|root,COG3225@2|Bacteria,46SRK@74201|Verrucomicrobia,2IU4Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	N	ABC-type uncharacterized transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_transp_aux
NEGHOLOK_01620	349741.Amuc_0006	0.0	1359.0	2DN50@1|root,32VJ4@2|Bacteria,46V62@74201|Verrucomicrobia,2IUH5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NEGHOLOK_01621	349741.Amuc_0007	1.57e-190	528.0	COG0327@1|root,COG0327@2|Bacteria,46U7Z@74201|Verrucomicrobia,2IU4W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	NIF3 (NGG1p interacting factor 3)	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NEGHOLOK_01622	349741.Amuc_0008	3.72e-237	651.0	COG0564@1|root,COG0564@2|Bacteria,46SQY@74201|Verrucomicrobia,2ITZF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Responsible for synthesis of pseudouridine from uracil	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NEGHOLOK_01623	349741.Amuc_0009	3.98e-277	758.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,46U8V@74201|Verrucomicrobia,2ITT8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Chorismate mutase type II	-	-	4.2.1.51,5.4.99.5	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NEGHOLOK_01624	349741.Amuc_0010	0.0	1108.0	COG3669@1|root,COG3669@2|Bacteria,46V90@74201|Verrucomicrobia,2IVNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
NEGHOLOK_01625	349741.Amuc_0011	0.0	1533.0	COG0272@1|root,COG0272@2|Bacteria,46TMK@74201|Verrucomicrobia,2ITPR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	-	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NEGHOLOK_01626	349741.Amuc_0012	1.03e-144	407.0	COG0558@1|root,COG0558@2|Bacteria,46VZY@74201|Verrucomicrobia,2IUG1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NEGHOLOK_01628	349741.Amuc_0015	5.78e-287	786.0	COG0513@1|root,COG0513@2|Bacteria,46S5M@74201|Verrucomicrobia,2IU0Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	helicase superfamily c-terminal domain	-	-	3.6.4.13	ko:K11927	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DEAD,Helicase_C
NEGHOLOK_01630	349741.Amuc_0017	0.0	1000.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,TAT_signal
NEGHOLOK_01631	349741.Amuc_0018	5.73e-288	785.0	COG1082@1|root,COG1082@2|Bacteria,46UXT@74201|Verrucomicrobia,2ITIF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase domain protein TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01632	349741.Amuc_0019	1.49e-225	622.0	COG2234@1|root,COG2234@2|Bacteria	2|Bacteria	DZ	aminopeptidase activity	-	-	3.4.11.10,3.4.11.6	ko:K19701	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M28
NEGHOLOK_01633	349741.Amuc_0020	2.23e-272	746.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	ycaD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K08219	-	-	-	-	ko00000,ko02000	2.A.1.26	-	-	MFS_1,Sugar_tr
NEGHOLOK_01634	349741.Amuc_0021	8.94e-317	865.0	COG1508@1|root,COG1508@2|Bacteria,46SDZ@74201|Verrucomicrobia,2ITMX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Sigma-54 factor, Activator interacting domain (AID)	-	-	-	ko:K03092	ko02020,ko05111,map02020,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma54_AID,Sigma54_CBD,Sigma54_DBD
NEGHOLOK_01635	349741.Amuc_0022	9.46e-176	489.0	COG2755@1|root,COG2755@2|Bacteria,46SSC@74201|Verrucomicrobia,2IUJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_01636	349741.Amuc_0023	4.17e-190	527.0	COG0384@1|root,COG0384@2|Bacteria,46SN8@74201|Verrucomicrobia,2IU9G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
NEGHOLOK_01638	349741.Amuc_0024	8.84e-140	395.0	COG1971@1|root,COG1971@2|Bacteria	2|Bacteria	P	manganese ion transmembrane transporter activity	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NEGHOLOK_01639	349741.Amuc_0025	0.0	1507.0	2DV5S@1|root,33U70@2|Bacteria,46XA4@74201|Verrucomicrobia,2IV64@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01640	349741.Amuc_0026	1.38e-294	803.0	2DYWX@1|root,34BHD@2|Bacteria,46X03@74201|Verrucomicrobia,2IW8K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01641	349741.Amuc_0027	0.0	882.0	COG2256@1|root,COG2256@2|Bacteria,46S7H@74201|Verrucomicrobia,2ITKR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NEGHOLOK_01643	349741.Amuc_0029	1.01e-222	613.0	COG0451@1|root,COG0451@2|Bacteria,46UCR@74201|Verrucomicrobia,2IWKH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
NEGHOLOK_01644	349741.Amuc_0030	8.25e-273	745.0	COG2334@1|root,COG2334@2|Bacteria,46TIS@74201|Verrucomicrobia,2IVEV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
NEGHOLOK_01645	349741.Amuc_0031	2.27e-215	593.0	COG1208@1|root,COG1208@2|Bacteria,46UYH@74201|Verrucomicrobia,2ITZR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	JM	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3,NTP_transferase
NEGHOLOK_01647	349741.Amuc_0033	2.04e-158	444.0	COG1994@1|root,COG1994@2|Bacteria,46VDN@74201|Verrucomicrobia,2IUVX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
NEGHOLOK_01648	349741.Amuc_0034	0.0	1031.0	COG0442@1|root,COG0442@2|Bacteria,46SE3@74201|Verrucomicrobia,2ITKS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Prolyl-tRNA synthetase, C-terminal	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NEGHOLOK_01651	349741.Amuc_0036	3.12e-202	610.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_01652	349741.Amuc_0036	0.0	3192.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_01653	349741.Amuc_0037	0.0	958.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	ko:K20265	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.3.7.1,2.A.3.7.3	-	-	AA_permease_2
NEGHOLOK_01654	349741.Amuc_0038	1.43e-220	608.0	COG2066@1|root,COG2066@2|Bacteria,46SKT@74201|Verrucomicrobia,2IWMT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glutaminase	-	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
NEGHOLOK_01655	349741.Amuc_0039	2.43e-95	277.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
NEGHOLOK_01656	349741.Amuc_0040	7.09e-309	845.0	COG1115@1|root,COG1115@2|Bacteria,46TWQ@74201|Verrucomicrobia,2IU9Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NEGHOLOK_01658	349741.Amuc_0041	3.95e-252	692.0	COG0216@1|root,COG0216@2|Bacteria,46S6F@74201|Verrucomicrobia,2ITHW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NEGHOLOK_01659	349741.Amuc_0042	1.65e-213	590.0	COG2890@1|root,COG2890@2|Bacteria,46SZE@74201|Verrucomicrobia,2IU5P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
NEGHOLOK_01660	349741.Amuc_0043	0.0	1440.0	COG1198@1|root,COG1198@2|Bacteria,46U3N@74201|Verrucomicrobia,2ITWU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NEGHOLOK_01661	349741.Amuc_0044	1.25e-199	552.0	COG0253@1|root,COG0253@2|Bacteria,46SKV@74201|Verrucomicrobia,2ITVJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NEGHOLOK_01665	349741.Amuc_0047	4.33e-161	451.0	COG0500@1|root,COG2226@2|Bacteria,46STX@74201|Verrucomicrobia,2IU7J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	Q	ubiE/COQ5 methyltransferase family	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
NEGHOLOK_01666	349741.Amuc_0048	0.0	977.0	COG0534@1|root,COG0534@2|Bacteria,46Z02@74201|Verrucomicrobia,2IU41@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NEGHOLOK_01668	349741.Amuc_1040	0.0	2754.0	COG0086@1|root,COG0086@2|Bacteria,46S79@74201|Verrucomicrobia,2ITYC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
NEGHOLOK_01670	349741.Amuc_1042	3.69e-64	197.0	COG0222@1|root,COG0222@2|Bacteria,46SWC@74201|Verrucomicrobia,2IUI8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NEGHOLOK_01671	349741.Amuc_1043	9.92e-110	316.0	COG0244@1|root,COG0244@2|Bacteria,46T4Q@74201|Verrucomicrobia,2IUF1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NEGHOLOK_01672	349741.Amuc_1044	4.97e-156	439.0	COG0081@1|root,COG0081@2|Bacteria,46S7K@74201|Verrucomicrobia,2ITZ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NEGHOLOK_01673	349741.Amuc_1045	2.58e-93	273.0	COG0080@1|root,COG0080@2|Bacteria,46SPZ@74201|Verrucomicrobia,2IUAM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NEGHOLOK_01674	349741.Amuc_1046	6.29e-135	382.0	COG0250@1|root,COG0250@2|Bacteria,46SR6@74201|Verrucomicrobia,2IU6S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NEGHOLOK_01675	349741.Amuc_1047	3.61e-46	148.0	COG0690@1|root,COG0690@2|Bacteria,46T9W@74201|Verrucomicrobia,2IUWV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	SecE/Sec61-gamma subunits of protein translocation complex	-	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NEGHOLOK_01677	349741.Amuc_1048	9.94e-287	783.0	COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NEGHOLOK_01679	349741.Amuc_1049	8.34e-255	699.0	COG0533@1|root,COG0533@2|Bacteria,46SEH@74201|Verrucomicrobia,2ITUT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NEGHOLOK_01680	349741.Amuc_1050	0.0	889.0	COG1219@1|root,COG1219@2|Bacteria,46SIK@74201|Verrucomicrobia,2ITIB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NEGHOLOK_01681	349741.Amuc_1051	2.5e-153	431.0	COG0740@1|root,COG0740@2|Bacteria,46SAB@74201|Verrucomicrobia,2ITX1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NEGHOLOK_01682	349741.Amuc_1052	8.38e-282	774.0	COG0544@1|root,COG0544@2|Bacteria,46SJZ@74201|Verrucomicrobia,2ITGE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NEGHOLOK_01683	349741.Amuc_1053	0.0	1623.0	COG4775@1|root,COG4775@2|Bacteria,46S5F@74201|Verrucomicrobia,2ITS5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Surface antigen	-	-	-	ko:K07277	-	-	-	-	ko00000,ko02000,ko03029	1.B.33	-	-	Bac_surface_Ag,POTRA
NEGHOLOK_01684	349741.Amuc_1054	5.9e-156	440.0	COG2850@1|root,COG2850@2|Bacteria	2|Bacteria	P	peptidyl-arginine hydroxylation	-	-	1.14.11.27	ko:K10277	-	-	-	-	ko00000,ko01000,ko03036	-	-	-	Cupin_8
NEGHOLOK_01685	349741.Amuc_1055	2.6e-231	635.0	COG0685@1|root,COG0685@2|Bacteria,46UW6@74201|Verrucomicrobia,2ITT5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Methylenetetrahydrofolate reductase	-	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NEGHOLOK_01686	349741.Amuc_1056	1.38e-168	471.0	COG2976@1|root,COG2976@2|Bacteria	2|Bacteria	CO	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_21,TPR_6,TPR_8
NEGHOLOK_01688	349741.Amuc_1058	1.46e-147	415.0	COG1309@1|root,COG1309@2|Bacteria,46XR9@74201|Verrucomicrobia,2IWEP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NEGHOLOK_01689	349741.Amuc_1059	0.0	1955.0	COG3696@1|root,COG3696@2|Bacteria,46USJ@74201|Verrucomicrobia,2ITM5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	AcrB/AcrD/AcrF family	-	-	-	ko:K07239	-	-	-	-	ko00000	2.A.6.1	-	-	ACR_tran
NEGHOLOK_01690	349741.Amuc_1060	1.96e-297	816.0	COG0845@1|root,COG0845@2|Bacteria	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	czcB	-	-	ko:K15727	-	-	-	-	ko00000,ko02000	8.A.1.2.1	-	-	HlyD_D23
NEGHOLOK_01691	349741.Amuc_1061	3.69e-296	809.0	COG1538@1|root,COG1538@2|Bacteria	2|Bacteria	MU	efflux transmembrane transporter activity	-	-	-	ko:K15725	-	-	-	-	ko00000,ko02000	1.B.17.2.2	-	-	OEP
NEGHOLOK_01693	349741.Amuc_1063	3.17e-206	575.0	COG0666@1|root,COG0666@2|Bacteria	2|Bacteria	G	response to abiotic stimulus	-	-	-	ko:K06867,ko:K07001	-	-	-	-	ko00000	-	-	-	Ank,Ank_2,Ank_4,Ank_5,Fic,Sel1
NEGHOLOK_01694	349741.Amuc_1064	0.0	954.0	COG3104@1|root,COG3104@2|Bacteria,46VMC@74201|Verrucomicrobia	74201|Verrucomicrobia	E	PFAM major facilitator superfamily MFS_1	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NEGHOLOK_01697	349741.Amuc_1067	1.66e-215	595.0	COG0500@1|root,COG0640@1|root,COG0640@2|Bacteria,COG2226@2|Bacteria,46SDC@74201|Verrucomicrobia,2ITX6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KQ	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5,Methyltransf_11,Methyltransf_31
NEGHOLOK_01698	349741.Amuc_1068	3.77e-291	794.0	COG0192@1|root,COG0192@2|Bacteria,46S4V@74201|Verrucomicrobia,2ITRU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NEGHOLOK_01699	349741.Amuc_1069	0.0	952.0	COG0499@1|root,COG0499@2|Bacteria,46SGX@74201|Verrucomicrobia,2ITJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	-	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
NEGHOLOK_01700	349741.Amuc_1070	1.81e-251	689.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rgpB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01701	349741.Amuc_1071	1.87e-248	680.0	2E0IP@1|root,32W4A@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01702	349741.Amuc_1072	0.0	862.0	COG1232@1|root,COG1232@2|Bacteria,46Z36@74201|Verrucomicrobia,2IUYM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
NEGHOLOK_01703	349741.Amuc_1073	1.44e-225	620.0	2A4B8@1|root,30SWV@2|Bacteria	349741.Amuc_1073|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01704	349741.Amuc_1074	0.0	1174.0	COG3119@1|root,COG3119@2|Bacteria,46U1Z@74201|Verrucomicrobia,2ITR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NEGHOLOK_01705	349741.Amuc_1075	0.0	1257.0	COG0514@1|root,COG0514@2|Bacteria,46UKY@74201|Verrucomicrobia,2ITR5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RecQ zinc-binding	-	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecQ_Zn_bind
NEGHOLOK_01707	349741.Amuc_1077	1.45e-299	816.0	COG0438@1|root,COG0438@2|Bacteria,46ZHN@74201|Verrucomicrobia,2IUVI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NEGHOLOK_01708	349741.Amuc_1078	1.62e-256	702.0	COG3868@1|root,COG3868@2|Bacteria,46STS@74201|Verrucomicrobia,2IU5G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycoside-hydrolase family GH114	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01709	349741.Amuc_1079	0.0	1082.0	COG0029@1|root,COG0029@2|Bacteria,46SHQ@74201|Verrucomicrobia,2ITSA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Fumarate reductase flavoprotein C-term	-	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NEGHOLOK_01710	349741.Amuc_1080	2.86e-133	378.0	COG0566@1|root,COG0566@2|Bacteria,46VH3@74201|Verrucomicrobia,2IUB5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	SpoU rRNA Methylase family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase
NEGHOLOK_01711	349741.Amuc_1081	4.56e-206	568.0	COG0420@1|root,COG0420@2|Bacteria	2|Bacteria	L	3'-5' exonuclease activity	-	-	3.1.1.53	ko:K03547,ko:K05970	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Metallophos,Metallophos_2
NEGHOLOK_01712	349741.Amuc_1082	4.92e-90	264.0	COG1321@1|root,COG1321@2|Bacteria,46VZN@74201|Verrucomicrobia,2IUJN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NEGHOLOK_01713	349741.Amuc_1083	0.0	1313.0	COG2217@1|root,COG2217@2|Bacteria,46UK0@74201|Verrucomicrobia,2ITIY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ATPase-cat_bd,E1-E2_ATPase,Hydrolase
NEGHOLOK_01715	349741.Amuc_1085	1.63e-302	823.0	COG3659@1|root,COG3659@2|Bacteria	2|Bacteria	M	wide pore channel activity	-	-	-	ko:K07267	-	-	-	-	ko00000,ko02000	1.B.19.1	-	-	OprB,SLH
NEGHOLOK_01718	349741.Amuc_1088	0.0	1403.0	COG0370@1|root,COG0370@2|Bacteria,46SH4@74201|Verrucomicrobia,2ITUZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Ferrous iron transport protein B C terminus	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NEGHOLOK_01719	349741.Amuc_1089	4.02e-48	153.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NEGHOLOK_01720	349741.Amuc_1090	2.48e-40	134.0	COG1918@1|root,COG1918@2|Bacteria	2|Bacteria	P	iron ion homeostasis	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NEGHOLOK_01721	349741.Amuc_1091	0.0	937.0	COG1858@1|root,COG1858@2|Bacteria,46U0N@74201|Verrucomicrobia,2IUGP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG,Cytochrom_C
NEGHOLOK_01722	349741.Amuc_1092	5.44e-229	630.0	COG0320@1|root,COG0320@2|Bacteria,46TZG@74201|Verrucomicrobia,2ITX7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	LIAS_N,Radical_SAM
NEGHOLOK_01723	349741.Amuc_1093	1.1e-131	373.0	COG0590@1|root,COG0590@2|Bacteria,46SZZ@74201|Verrucomicrobia,2IUAZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NEGHOLOK_01724	349741.Amuc_1094	1.65e-240	660.0	COG1940@1|root,COG1940@2|Bacteria,46T0E@74201|Verrucomicrobia,2ITKM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NEGHOLOK_01725	349741.Amuc_1095	0.0	1202.0	COG2217@1|root,COG2217@2|Bacteria,46TN5@74201|Verrucomicrobia,2IWNK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
NEGHOLOK_01726	349741.Amuc_1096	0.0	898.0	COG1158@1|root,COG1158@2|Bacteria,46S5Y@74201|Verrucomicrobia,2ITR1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	-	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_RNA_bind
NEGHOLOK_01727	349741.Amuc_1097	1.85e-142	402.0	COG0237@1|root,COG0237@2|Bacteria,46X3P@74201|Verrucomicrobia,2IUJH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NEGHOLOK_01728	349741.Amuc_1098	0.0	1743.0	COG0457@1|root,COG1450@1|root,COG0457@2|Bacteria,COG1450@2|Bacteria,46TXY@74201|Verrucomicrobia,2ITGX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Bacterial type II and III secretion system protein	-	-	-	ko:K02453	ko03070,ko05111,map03070,map05111	M00331	-	-	ko00000,ko00001,ko00002,ko02044	3.A.15	-	-	Secretin
NEGHOLOK_01729	349741.Amuc_1099	2.27e-245	673.0	2AW6M@1|root,31N1N@2|Bacteria,46X8K@74201|Verrucomicrobia,2IV0K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01730	349741.Amuc_1100	8.68e-208	577.0	28V7G@1|root,2ZHAM@2|Bacteria,46WJH@74201|Verrucomicrobia,2IUZ5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01731	349741.Amuc_1101	0.0	1130.0	COG4972@1|root,COG4972@2|Bacteria,46UI7@74201|Verrucomicrobia,2ITTF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	NU	Type IV pilus assembly protein PilM;	-	-	-	-	-	-	-	-	-	-	-	-	PilM_2
NEGHOLOK_01732	349741.Amuc_1102	2.8e-169	473.0	28VCA@1|root,2ZHF0@2|Bacteria,46WID@74201|Verrucomicrobia,2IUQZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01733	349741.Amuc_1103	9.39e-256	701.0	COG1363@1|root,COG1363@2|Bacteria,46YYD@74201|Verrucomicrobia,2ITUN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NEGHOLOK_01734	349741.Amuc_1104	1.3e-263	721.0	COG0682@1|root,COG0682@2|Bacteria,46SSY@74201|Verrucomicrobia,2IU4I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NEGHOLOK_01735	349741.Amuc_1105	2.82e-155	436.0	2DSS0@1|root,33H81@2|Bacteria,46XPW@74201|Verrucomicrobia,2IWCC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF3313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3313
NEGHOLOK_01736	349741.Amuc_1106	8.33e-314	854.0	COG0006@1|root,COG0006@2|Bacteria,46U30@74201|Verrucomicrobia,2ITPD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminopeptidase P, N-terminal domain	-	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	AMP_N,Peptidase_M24
NEGHOLOK_01737	349741.Amuc_1107	2.25e-206	571.0	COG0040@1|root,COG0040@2|Bacteria,46SHK@74201|Verrucomicrobia,2ITH9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
NEGHOLOK_01738	349741.Amuc_1108	2.09e-10	55.5	2A2WF@1|root,30RAJ@2|Bacteria,46Y7F@74201|Verrucomicrobia,2IUX3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Mitochondrial domain of unknown function (DUF1713)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1713
NEGHOLOK_01739	349741.Amuc_1109	8.6e-291	794.0	COG5002@1|root,COG5002@2|Bacteria,46SSA@74201|Verrucomicrobia,2ITKV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NEGHOLOK_01740	349741.Amuc_1110	6.89e-168	469.0	COG0745@1|root,COG0745@2|Bacteria,46SS3@74201|Verrucomicrobia,2IU6U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07657	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NEGHOLOK_01741	349741.Amuc_1111	0.0	1104.0	COG0129@1|root,COG0129@2|Bacteria,46SBY@74201|Verrucomicrobia,2ITPZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EG	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NEGHOLOK_01743	349741.Amuc_1114	0.0	2414.0	COG4625@1|root,COG4625@2|Bacteria	2|Bacteria	T	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Autotransporter
NEGHOLOK_01744	349741.Amuc_1115	4.71e-267	730.0	COG4974@1|root,COG4974@2|Bacteria,46Z6H@74201|Verrucomicrobia,2IWPR@203494|Verrucomicrobiae	2|Bacteria	L	Belongs to the 'phage' integrase family	xerD1	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NEGHOLOK_01745	349741.Amuc_1116	6.59e-205	568.0	COG1573@1|root,COG1573@2|Bacteria,46SSB@74201|Verrucomicrobia,2IU8Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NEGHOLOK_01746	349741.Amuc_1117	6.68e-286	779.0	COG0502@1|root,COG0502@2|Bacteria,46SFX@74201|Verrucomicrobia,2ITUU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin and Thiamin Synthesis associated domain	-	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NEGHOLOK_01747	349741.Amuc_1118	0.0	1280.0	COG1368@1|root,COG1368@2|Bacteria,46U99@74201|Verrucomicrobia,2IVIY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NEGHOLOK_01748	349741.Amuc_1119	3.09e-290	791.0	2EMB5@1|root,33F05@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01749	349741.Amuc_1120	0.0	1615.0	COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2
NEGHOLOK_01750	349741.Amuc_1121	0.0	922.0	28HQ3@1|root,2Z7XW@2|Bacteria,46U81@74201|Verrucomicrobia,2ITXI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF2851)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2851
NEGHOLOK_01751	349741.Amuc_1122	6.39e-119	340.0	COG1366@1|root,COG1366@2|Bacteria,46T4Z@74201|Verrucomicrobia,2IURI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
NEGHOLOK_01752	349741.Amuc_1123	0.0	879.0	COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia,2ITZJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
NEGHOLOK_01753	349741.Amuc_1124	0.0	898.0	COG1657@1|root,COG1657@2|Bacteria,46V9U@74201|Verrucomicrobia,2ITZJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Prenyltransferase and squalene oxidase repeat	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
NEGHOLOK_01754	349741.Amuc_1125	1.26e-247	678.0	COG1087@1|root,COG1087@2|Bacteria,46SIR@74201|Verrucomicrobia,2ITS1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	NmrA-like family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
NEGHOLOK_01755	349741.Amuc_1126	0.0	932.0	COG0030@1|root,COG1443@1|root,COG0030@2|Bacteria,COG1443@2|Bacteria,46T1S@74201|Verrucomicrobia,2ITVV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IJ	Ribosomal RNA adenine dimethylases	-	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	NUDIX,RrnaAD
NEGHOLOK_01756	349741.Amuc_1127	7.2e-103	298.0	2FBS3@1|root,343WW@2|Bacteria,46X6J@74201|Verrucomicrobia,2IUQ7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01757	349741.Amuc_1128	9.86e-54	168.0	2AX33@1|root,31P1F@2|Bacteria,46XQB@74201|Verrucomicrobia,2IWD6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01758	349741.Amuc_1129	1.83e-120	352.0	2AW63@1|root,31N13@2|Bacteria,46X8D@74201|Verrucomicrobia,2IUZY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01759	349741.Amuc_1131	3.53e-300	820.0	COG0534@1|root,COG0534@2|Bacteria	2|Bacteria	V	drug transmembrane transporter activity	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
NEGHOLOK_01760	349741.Amuc_1132	0.0	1156.0	COG0168@1|root,COG0168@2|Bacteria,46U92@74201|Verrucomicrobia,2IVH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transport protein	-	-	-	-	-	-	-	-	-	-	-	-	TrkH
NEGHOLOK_01763	349741.Amuc_1134	5.37e-148	415.0	COG1876@1|root,COG1876@2|Bacteria,46XIM@74201|Verrucomicrobia,2IW0P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	ko:K17733	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M15_4
NEGHOLOK_01769	349741.Amuc_1140	3.72e-265	724.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	ko:K16703	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
NEGHOLOK_01771	349741.Amuc_1142	0.0	1199.0	COG3774@1|root,COG3774@2|Bacteria,46W4E@74201|Verrucomicrobia	74201|Verrucomicrobia	M	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Gly_transf_sug
NEGHOLOK_01772	349741.Amuc_1143	0.0	3304.0	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_01774	349741.Amuc_0893	4.07e-97	283.0	COG3212@1|root,COG3212@2|Bacteria,46WQF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
NEGHOLOK_01775	349741.Amuc_0894	5.18e-172	481.0	COG2738@1|root,COG2738@2|Bacteria,46TH9@74201|Verrucomicrobia,2IUJW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NEGHOLOK_01776	349741.Amuc_0895	2.24e-101	294.0	COG3212@1|root,COG3212@2|Bacteria,46WQF@74201|Verrucomicrobia	74201|Verrucomicrobia	S	peptidase	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_like
NEGHOLOK_01777	349741.Amuc_0896	0.0	986.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,46S9P@74201|Verrucomicrobia,2ITRR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
NEGHOLOK_01778	349741.Amuc_0897	1.38e-90	265.0	2F8IJ@1|root,340XC@2|Bacteria,46WTZ@74201|Verrucomicrobia,2IUYP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01779	349741.Amuc_0898	0.0	1680.0	COG0550@1|root,COG0550@2|Bacteria,46S97@74201|Verrucomicrobia,2ITTZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bacterial DNA topoisomeraes I ATP-binding domain	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NEGHOLOK_01783	349741.Amuc_0903	8.8e-169	470.0	COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NEGHOLOK_01784	349741.Amuc_0904	0.0	1831.0	COG1048@1|root,COG1048@2|Bacteria,46SFS@74201|Verrucomicrobia,2ITHS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Aconitase C-terminal domain	-	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NEGHOLOK_01785	349741.Amuc_0905	2.57e-133	377.0	COG1376@1|root,COG1376@2|Bacteria	2|Bacteria	D	ErfK ybiS ycfS ynhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	Ank_2,YkuD
NEGHOLOK_01787	349741.Amuc_0906	2.51e-284	775.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,46SSF@74201|Verrucomicrobia,2IU9E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
NEGHOLOK_01789	349741.Amuc_0908	0.0	1519.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BACON,M60-like_N,Peptidase_M60,SBP_bac_5
NEGHOLOK_01790	349741.Amuc_0909	1.17e-271	743.0	COG1690@1|root,COG1690@2|Bacteria,46STD@74201|Verrucomicrobia,2IUZX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	tRNA-splicing ligase RtcB	-	-	-	-	-	-	-	-	-	-	-	-	RtcB
NEGHOLOK_01791	349741.Amuc_0910	4.75e-215	594.0	COG0583@1|root,COG0583@2|Bacteria,46V82@74201|Verrucomicrobia,2IVST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NEGHOLOK_01792	349741.Amuc_0911	3.03e-296	808.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
NEGHOLOK_01794	349741.Amuc_0913	7.1e-130	369.0	COG2096@1|root,COG2096@2|Bacteria,46T1G@74201|Verrucomicrobia,2IUKY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cobalamin adenosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Cob_adeno_trans
NEGHOLOK_01795	349741.Amuc_0914	6.52e-75	224.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NEGHOLOK_01796	349741.Amuc_0915	0.0	1489.0	COG0557@1|root,COG0557@2|Bacteria,46U8T@74201|Verrucomicrobia,2ITHQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NEGHOLOK_01798	349741.Amuc_0917	0.0	1662.0	COG0826@1|root,COG0826@2|Bacteria,46UGV@74201|Verrucomicrobia,2ITKP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Collagenase	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NEGHOLOK_01799	349741.Amuc_0918	1.12e-288	788.0	COG0285@1|root,COG0285@2|Bacteria,46SKD@74201|Verrucomicrobia,2ITNW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NEGHOLOK_01801	349741.Amuc_0920	0.0	963.0	COG0673@1|root,COG0673@2|Bacteria,46U7B@74201|Verrucomicrobia,2IV4V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NEGHOLOK_01802	349741.Amuc_0921	0.0	1766.0	COG0553@1|root,COG0553@2|Bacteria,46U9A@74201|Verrucomicrobia,2ITYK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 Helicase protein	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	DUF3670,Helicase_C,SNF2_N
NEGHOLOK_01803	349741.Amuc_0922	0.0	975.0	COG0737@1|root,COG0737@2|Bacteria,46X8F@74201|Verrucomicrobia,2IV06@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Calcineurin-like phosphoesterase	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NEGHOLOK_01804	349741.Amuc_0923	1.77e-124	354.0	COG0797@1|root,COG0797@2|Bacteria,46WTP@74201|Verrucomicrobia,2IUW1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Lytic transglycolase	-	-	-	ko:K03642	-	-	-	-	ko00000	-	-	-	DPBB_1
NEGHOLOK_01805	349741.Amuc_0924	4.9e-207	573.0	COG0061@1|root,COG0061@2|Bacteria,46SUQ@74201|Verrucomicrobia,2IUD8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	CTP_transf_like,NAD_kinase
NEGHOLOK_01806	349741.Amuc_0925	1.53e-47	152.0	COG0198@1|root,COG0198@2|Bacteria,46T3M@74201|Verrucomicrobia,2IUUE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S L24/mitochondrial 39S L24	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NEGHOLOK_01807	349741.Amuc_0926	5.36e-138	390.0	COG0094@1|root,COG0094@2|Bacteria,46SP7@74201|Verrucomicrobia,2ITU8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NEGHOLOK_01808	349741.Amuc_0927	4.08e-88	259.0	COG0096@1|root,COG0096@2|Bacteria,46T2K@74201|Verrucomicrobia,2IUCT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NEGHOLOK_01809	349741.Amuc_0928	2.25e-105	306.0	COG0097@1|root,COG0097@2|Bacteria,46SP9@74201|Verrucomicrobia,2IU69@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NEGHOLOK_01810	349741.Amuc_0929	2.38e-74	223.0	COG0256@1|root,COG0256@2|Bacteria,46T7Z@74201|Verrucomicrobia,2IUJF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NEGHOLOK_01811	349741.Amuc_0930	3.38e-102	299.0	COG0098@1|root,COG0098@2|Bacteria,46SUR@74201|Verrucomicrobia,2IUC7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NEGHOLOK_01812	349741.Amuc_0931	6.42e-101	293.0	COG0200@1|root,COG0200@2|Bacteria,46SSX@74201|Verrucomicrobia,2IUE6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NEGHOLOK_01814	349741.Amuc_0933	0.0	936.0	COG0201@1|root,COG0201@2|Bacteria,46S86@74201|Verrucomicrobia,2ITRX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NEGHOLOK_01815	349741.Amuc_0934	6.41e-155	434.0	COG0563@1|root,COG0563@2|Bacteria,46YYW@74201|Verrucomicrobia,2IUVY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
NEGHOLOK_01816	349741.Amuc_0935	1.29e-192	534.0	COG0024@1|root,COG0024@2|Bacteria,46SK6@74201|Verrucomicrobia,2ITSS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Metallopeptidase family M24	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NEGHOLOK_01817	349741.Amuc_0936	2e-264	723.0	COG4763@1|root,COG4763@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	ko:K11941	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
NEGHOLOK_01818	349741.Amuc_0937	0.0	1010.0	COG0248@1|root,COG2206@1|root,COG0248@2|Bacteria,COG2206@2|Bacteria,46YY5@74201|Verrucomicrobia,2ITTR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	FP	Ppx/GppA phosphatase family	-	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NEGHOLOK_01819	349741.Amuc_0938	0.0	1347.0	COG0855@1|root,COG0855@2|Bacteria,46SB4@74201|Verrucomicrobia,2ITZT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Polyphosphate kinase middle domain	-	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NEGHOLOK_01820	349741.Amuc_0939	1.19e-280	765.0	COG1442@1|root,COG1442@2|Bacteria,46WTH@74201|Verrucomicrobia	74201|Verrucomicrobia	H	PFAM glycosyl transferase family 8	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_8
NEGHOLOK_01822	349741.Amuc_0941	3.93e-272	744.0	COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia	2|Bacteria	S	PFAM glycosyl transferase family 2	-	-	-	ko:K19427	-	-	-	-	ko00000,ko01000	-	GT2	-	Glycos_transf_2
NEGHOLOK_01823	349741.Amuc_0942	3.06e-226	621.0	arCOG09486@1|root,2ZC3Y@2|Bacteria,46XJM@74201|Verrucomicrobia,2IW2Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11
NEGHOLOK_01824	349741.Amuc_0943	3.16e-259	709.0	COG1216@1|root,COG1216@2|Bacteria,46TK6@74201|Verrucomicrobia,2IUYU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01825	349741.Amuc_0944	2.27e-290	792.0	2DAWX@1|root,32TWB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01826	349741.Amuc_0945	8.81e-265	724.0	COG1216@1|root,COG1216@2|Bacteria,46W1P@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NEGHOLOK_01827	349741.Amuc_0946	3.93e-128	364.0	COG0693@1|root,COG0693@2|Bacteria,46Z1W@74201|Verrucomicrobia,2IUW2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NEGHOLOK_01828	349741.Amuc_0947	3.78e-228	630.0	COG0508@1|root,COG0508@2|Bacteria,46SHZ@74201|Verrucomicrobia,2IU2H@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	e3 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
NEGHOLOK_01829	349741.Amuc_0948	4.34e-284	775.0	COG1820@1|root,COG1820@2|Bacteria,46SRF@74201|Verrucomicrobia,2IU36@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	-	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NEGHOLOK_01830	349741.Amuc_0949	8.17e-135	382.0	COG0652@1|root,COG0652@2|Bacteria,46V73@74201|Verrucomicrobia,2IU91@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NEGHOLOK_01831	349741.Amuc_0950	0.0	899.0	COG0477@1|root,COG2814@2|Bacteria,46VGN@74201|Verrucomicrobia,2ITZY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EGIP	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,MFS_1
NEGHOLOK_01832	349741.Amuc_0951	0.0	942.0	COG1966@1|root,COG1966@2|Bacteria,46SC3@74201|Verrucomicrobia,2IU78@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	5TM C-terminal transporter carbon starvation CstA	-	-	-	-	-	-	-	-	-	-	-	-	CstA,CstA_5TM
NEGHOLOK_01833	349741.Amuc_0952	8.65e-155	437.0	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01834	349741.Amuc_0952	1.28e-15	81.3	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01835	349741.Amuc_0953	0.0	2808.0	COG3119@1|root,COG3119@2|Bacteria,46UIA@74201|Verrucomicrobia,2IVFY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	PA14 domain	-	-	-	-	-	-	-	-	-	-	-	-	PA14,Sulfatase
NEGHOLOK_01836	349741.Amuc_0955	2e-82	244.0	COG0858@1|root,COG0858@2|Bacteria,46TBI@74201|Verrucomicrobia,2IUMI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NEGHOLOK_01837	349741.Amuc_0956	0.0	1269.0	COG0532@1|root,COG0532@2|Bacteria,46S8V@74201|Verrucomicrobia,2ITNN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NEGHOLOK_01838	349741.Amuc_0957	5.58e-289	791.0	COG0195@1|root,COG0195@2|Bacteria,46TRP@74201|Verrucomicrobia,2ITT2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	NusA-like KH domain	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NEGHOLOK_01839	349741.Amuc_0958	3.73e-195	539.0	COG0708@1|root,COG0708@2|Bacteria,46TGT@74201|Verrucomicrobia,2IU1A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Endonuclease/Exonuclease/phosphatase family	-	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NEGHOLOK_01840	349741.Amuc_0959	2.86e-143	404.0	COG0127@1|root,COG0127@2|Bacteria,46SZ5@74201|Verrucomicrobia,2IU83@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	-	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NEGHOLOK_01841	349741.Amuc_0960	1.49e-135	385.0	COG2519@1|root,COG2519@2|Bacteria,46VQ7@74201|Verrucomicrobia,2IUKX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
NEGHOLOK_01842	349741.Amuc_0961	3.3e-203	563.0	COG2006@1|root,COG2006@2|Bacteria,46U2P@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
NEGHOLOK_01843	349741.Amuc_0962	0.0	1147.0	COG0348@1|root,COG1143@1|root,COG0348@2|Bacteria,COG1143@2|Bacteria,46UPW@74201|Verrucomicrobia	74201|Verrucomicrobia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_7
NEGHOLOK_01844	349741.Amuc_0963	0.0	1138.0	COG1131@1|root,COG1668@1|root,COG1131@2|Bacteria,COG1668@2|Bacteria,46SII@74201|Verrucomicrobia,2ITQM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane,ABC_tran
NEGHOLOK_01846	349741.Amuc_0965	0.0	1190.0	2BZ41@1|root,2ZDAE@2|Bacteria,46SM4@74201|Verrucomicrobia,2ITI9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01847	349741.Amuc_0966	3.54e-185	513.0	COG3786@1|root,COG3786@2|Bacteria,46STB@74201|Verrucomicrobia,2IUPE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_01848	349741.Amuc_0967	7.33e-143	404.0	COG0724@1|root,COG0724@2|Bacteria,46WD6@74201|Verrucomicrobia,2IUKQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RNA recognition motif	-	-	-	-	-	-	-	-	-	-	-	-	RRM_1
NEGHOLOK_01849	349741.Amuc_0968	0.0	902.0	COG2148@1|root,COG2148@2|Bacteria,46TSZ@74201|Verrucomicrobia,2ITYD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NEGHOLOK_01850	349741.Amuc_0969	8.88e-284	775.0	COG0153@1|root,COG0153@2|Bacteria,46V7W@74201|Verrucomicrobia,2IU6C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Galactokinase galactose-binding signature	-	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NEGHOLOK_01851	349741.Amuc_0970	0.0	1421.0	COG4146@1|root,COG4146@2|Bacteria,46UV3@74201|Verrucomicrobia,2ITNB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
NEGHOLOK_01853	349741.Amuc_0971	0.0	1311.0	COG0210@1|root,COG0210@2|Bacteria,46THX@74201|Verrucomicrobia,2ITGV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NEGHOLOK_01854	349741.Amuc_0972	3.02e-227	625.0	COG0223@1|root,COG0223@2|Bacteria,46SKS@74201|Verrucomicrobia,2ITWX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NEGHOLOK_01855	349741.Amuc_0973	1.18e-273	748.0	COG0707@1|root,COG0707@2|Bacteria,46SK7@74201|Verrucomicrobia,2IU5J@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Monogalactosyldiacylglycerol (MGDG) synthase	-	-	-	-	-	-	-	-	-	-	-	-	MGDG_synth
NEGHOLOK_01856	349741.Amuc_0974	7.16e-174	484.0	COG1521@1|root,COG1521@2|Bacteria,46T0X@74201|Verrucomicrobia,2IU5A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Type III pantothenate kinase	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NEGHOLOK_01857	349741.Amuc_0975	8.56e-45	145.0	COG0236@1|root,COG0236@2|Bacteria,46T18@74201|Verrucomicrobia,2IUTD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Phosphopantetheine attachment site	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NEGHOLOK_01858	349741.Amuc_0976	3.5e-132	375.0	2CNXM@1|root,32SI1@2|Bacteria,46SZC@74201|Verrucomicrobia,2IUHE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01859	349741.Amuc_0977	1.67e-174	487.0	COG1376@1|root,COG1376@2|Bacteria,46W0P@74201|Verrucomicrobia,2IURM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NEGHOLOK_01860	349741.Amuc_0978	5.31e-99	288.0	COG1490@1|root,COG1490@2|Bacteria,46STH@74201|Verrucomicrobia,2IUCY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NEGHOLOK_01862	349741.Amuc_0982	7.38e-17	84.3	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DNase_NucA_NucB,Endonuclea_NS_2,RHS_repeat
NEGHOLOK_01864	349741.Amuc_0175	5.88e-277	758.0	COG0265@1|root,COG0265@2|Bacteria,46ZCC@74201|Verrucomicrobia,2IUF5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
NEGHOLOK_01865	349741.Amuc_0176	9.19e-229	630.0	COG0265@1|root,COG0265@2|Bacteria,46ZF6@74201|Verrucomicrobia,2IU58@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin-like peptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
NEGHOLOK_01866	349741.Amuc_0177	0.0	1711.0	COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia,2ITYQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NEGHOLOK_01867	349741.Amuc_0178	1.21e-285	782.0	COG1322@1|root,COG1322@2|Bacteria,46THH@74201|Verrucomicrobia,2IUNZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
NEGHOLOK_01868	349741.Amuc_0179	5.69e-171	476.0	COG0546@1|root,COG0546@2|Bacteria,46WZP@74201|Verrucomicrobia,2IUMS@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	HAD-hyrolase-like	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NEGHOLOK_01869	349741.Amuc_0180	1.25e-132	382.0	COG1043@1|root,COG1043@2|Bacteria,46SD4@74201|Verrucomicrobia,2ITXD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell	-	-	2.3.1.129	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	M00060	R04567	RC00039,RC00055	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Acetyltransf_11,Hexapep
NEGHOLOK_01870	349741.Amuc_0181	7.56e-208	574.0	COG1714@1|root,COG1714@2|Bacteria,46ZIK@74201|Verrucomicrobia,2IV0N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
NEGHOLOK_01871	349741.Amuc_0182	0.0	1023.0	COG4591@1|root,COG4591@2|Bacteria,46SKZ@74201|Verrucomicrobia,2ITIK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	MacB-like periplasmic core domain	-	-	-	ko:K09808	ko02010,map02010	M00255	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.125	-	-	FtsX,MacB_PCD
NEGHOLOK_01872	349741.Amuc_0183	1.38e-209	580.0	COG2367@1|root,COG2367@2|Bacteria,46XT3@74201|Verrucomicrobia,2IWHY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
NEGHOLOK_01873	349741.Amuc_0184	2.27e-90	267.0	COG2839@1|root,COG2839@2|Bacteria,46WEX@74201|Verrucomicrobia,2IUVN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
NEGHOLOK_01874	349741.Amuc_0185	4.81e-58	180.0	2DVAH@1|root,32UZ0@2|Bacteria	2|Bacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784,bPH_5
NEGHOLOK_01875	349741.Amuc_0186	0.0	1620.0	COG1554@1|root,COG1554@2|Bacteria,46TM2@74201|Verrucomicrobia,2IV0H@203494|Verrucomicrobiae	2|Bacteria	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	3.2.1.51	ko:K15923	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000	-	GH95	-	Glyco_hyd_65N_2,Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
NEGHOLOK_01876	349741.Amuc_0187	1.55e-258	708.0	COG2234@1|root,COG2234@2|Bacteria,46XPN@74201|Verrucomicrobia,2IWC0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
NEGHOLOK_01877	349741.Amuc_0188	3.92e-246	676.0	COG0657@1|root,COG0657@2|Bacteria,46SRP@74201|Verrucomicrobia,2IUAQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NEGHOLOK_01878	349741.Amuc_0189	0.0	1844.0	COG0060@1|root,COG0060@2|Bacteria,46SEC@74201|Verrucomicrobia,2ITJZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
NEGHOLOK_01879	349741.Amuc_0190	1.24e-186	518.0	COG0597@1|root,COG0597@2|Bacteria,46TCC@74201|Verrucomicrobia,2IUIT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	MU	Signal peptidase (SPase) II	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NEGHOLOK_01880	349741.Amuc_0191	6.88e-152	427.0	2EJX7@1|root,33DMV@2|Bacteria,46WSK@74201|Verrucomicrobia,2IUU7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1573)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1573
NEGHOLOK_01881	349741.Amuc_0192	3.13e-114	327.0	COG0607@1|root,COG0607@2|Bacteria,46T32@74201|Verrucomicrobia,2IUWC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NEGHOLOK_01882	349741.Amuc_0193	1.9e-298	813.0	COG0520@1|root,COG0520@2|Bacteria,46S58@74201|Verrucomicrobia,2IU2B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
NEGHOLOK_01883	349741.Amuc_0194	0.0	1158.0	COG1075@1|root,COG1075@2|Bacteria,46Z7G@74201|Verrucomicrobia,2IU8E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01884	5888.CAK65535	0.000231	52.8	KOG0032@1|root,KOG0032@2759|Eukaryota	2759|Eukaryota	T	protein serine/threonine kinase activity	-	-	2.7.11.1,2.7.11.17	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	DUF1752,Pkinase
NEGHOLOK_01886	349741.Amuc_0198	8.14e-75	224.0	COG0335@1|root,COG0335@2|Bacteria,46T0S@74201|Verrucomicrobia,2IUD1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NEGHOLOK_01887	349741.Amuc_0199	0.0	1031.0	COG0457@1|root,COG0457@2|Bacteria,46SRS@74201|Verrucomicrobia,2IU3T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01888	349741.Amuc_0200	4.12e-100	290.0	COG0346@1|root,COG0346@2|Bacteria,46VJH@74201|Verrucomicrobia,2IVW3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Glyoxalase-like domain	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
NEGHOLOK_01889	349741.Amuc_0201	0.0	1028.0	COG4799@1|root,COG4799@2|Bacteria,46Z6F@74201|Verrucomicrobia,2IWPP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
NEGHOLOK_01891	349741.Amuc_0203	6.88e-55	175.0	COG0511@1|root,COG0511@2|Bacteria,46VQF@74201|Verrucomicrobia	74201|Verrucomicrobia	I	PFAM biotin lipoyl attachment domain-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NEGHOLOK_01892	349741.Amuc_0204	0.0	1038.0	COG1883@1|root,COG1883@2|Bacteria,46TTY@74201|Verrucomicrobia,2IVBT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Na+-transporting oxaloacetate decarboxylase beta subunit	-	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
NEGHOLOK_01893	349741.Amuc_0205	2.72e-191	530.0	COG0340@1|root,COG0340@2|Bacteria,46SX6@74201|Verrucomicrobia,2IUHW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Biotin/lipoate A/B protein ligase family	-	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
NEGHOLOK_01894	349741.Amuc_0206	0.0	990.0	COG0427@1|root,COG0427@2|Bacteria,46TQC@74201|Verrucomicrobia,2IUYA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Acetyl-CoA hydrolase/transferase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
NEGHOLOK_01896	349741.Amuc_0208	2.24e-204	565.0	COG1209@1|root,COG1209@2|Bacteria,46SHD@74201|Verrucomicrobia,2ITVA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	-	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NEGHOLOK_01897	349741.Amuc_0209	7.56e-271	739.0	COG1088@1|root,COG1088@2|Bacteria,46S98@74201|Verrucomicrobia,2IU1G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Male sterility protein	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NEGHOLOK_01898	349741.Amuc_0210	1.13e-228	629.0	COG0205@1|root,COG0205@2|Bacteria,46SFN@74201|Verrucomicrobia,2ITK8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphofructokinase	-	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NEGHOLOK_01899	349741.Amuc_0211	4.51e-182	505.0	COG1573@1|root,COG1573@2|Bacteria,46UE4@74201|Verrucomicrobia,2ITSY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	uracil-dna glycosylase	-	-	-	ko:K10800	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NEGHOLOK_01901	349741.Amuc_0213	0.0	969.0	COG0064@1|root,COG0064@2|Bacteria,46S5X@74201|Verrucomicrobia,2ITJA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NEGHOLOK_01902	349741.Amuc_0214	0.0	1156.0	COG0028@1|root,COG0028@2|Bacteria,46S72@74201|Verrucomicrobia,2ITSM@203494|Verrucomicrobiae	2|Bacteria	EH	Thiamine pyrophosphate enzyme, central domain	poxB	-	1.2.3.3,1.2.5.1	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	-	R00207,R03145	RC00860,RC02745	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NEGHOLOK_01903	349741.Amuc_0952	0.000225	49.7	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01904	349741.Amuc_0216	0.0	1716.0	COG3345@1|root,COG3345@2|Bacteria,46XJC@74201|Verrucomicrobia,2IW2A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	alpha-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01906	349741.Amuc_0218	0.0	1768.0	COG0474@1|root,COG0474@2|Bacteria,46TTZ@74201|Verrucomicrobia,2IVBX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NEGHOLOK_01907	349741.Amuc_0219	1.53e-284	778.0	COG0845@1|root,COG0845@2|Bacteria,46X9T@74201|Verrucomicrobia,2IVR2@203494|Verrucomicrobiae	2|Bacteria	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	mtrC	-	-	ko:K03585	ko01501,ko01503,map01501,map01503	M00646,M00647,M00699,M00718	-	-	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	2.A.6.2,8.A.1.6	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NEGHOLOK_01908	349741.Amuc_0220	0.0	1978.0	COG0841@1|root,COG0841@2|Bacteria,46SDN@74201|Verrucomicrobia,2IWND@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NEGHOLOK_01909	349741.Amuc_0221	9.04e-317	864.0	COG0471@1|root,COG0471@2|Bacteria,46UPI@74201|Verrucomicrobia,2IU88@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
NEGHOLOK_01911	349741.Amuc_0223	6.08e-178	496.0	COG0351@1|root,COG0351@2|Bacteria,46SVN@74201|Verrucomicrobia,2IU7Q@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Phosphomethylpyrimidine kinase	-	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NEGHOLOK_01913	349741.Amuc_0225	7.63e-166	473.0	COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
NEGHOLOK_01916	349741.Amuc_0228	0.0	1297.0	COG0827@1|root,COG0827@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase,TaqI_C
NEGHOLOK_01919	349741.Amuc_0229	3.92e-115	330.0	2C6YV@1|root,3392Q@2|Bacteria,46T7D@74201|Verrucomicrobia,2IUKV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01920	349741.Amuc_0230	4.46e-182	507.0	COG1028@1|root,COG1028@2|Bacteria,46VVI@74201|Verrucomicrobia,2IVZ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NEGHOLOK_01922	349741.Amuc_0232	5.46e-161	451.0	COG0242@1|root,COG0242@2|Bacteria,46SYF@74201|Verrucomicrobia,2IUCF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	-	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NEGHOLOK_01923	349741.Amuc_0233	5.91e-261	713.0	COG1063@1|root,COG1063@2|Bacteria,46UMA@74201|Verrucomicrobia,2ITX5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Alcohol dehydrogenase GroES-like domain	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NEGHOLOK_01924	349741.Amuc_0235	0.0	1135.0	COG0058@1|root,COG0058@2|Bacteria,46TZP@74201|Verrucomicrobia,2IVFU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Carbohydrate phosphorylase	-	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NEGHOLOK_01925	349741.Amuc_0236	8.34e-180	501.0	COG0569@1|root,COG0569@2|Bacteria	2|Bacteria	P	domain protein	-	-	-	ko:K10716	-	-	-	-	ko00000,ko02000	1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6	-	-	Ion_trans,Ion_trans_2,TrkA_C
NEGHOLOK_01926	349741.Amuc_0237	1.55e-83	246.0	COG1393@1|root,COG1393@2|Bacteria,46VTP@74201|Verrucomicrobia,2IUPM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
NEGHOLOK_01927	349741.Amuc_0238	0.0	968.0	COG1236@1|root,COG1236@2|Bacteria,46UFS@74201|Verrucomicrobia,2ITNR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Beta-Casp domain	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
NEGHOLOK_01928	349741.Amuc_0240	8.48e-56	174.0	COG1826@1|root,COG1826@2|Bacteria,46WPX@74201|Verrucomicrobia,2IURB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	tatA	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
NEGHOLOK_01929	349741.Amuc_0241	8.75e-240	671.0	COG0790@1|root,COG0790@2|Bacteria,46SWR@74201|Verrucomicrobia	74201|Verrucomicrobia	S	PFAM Sel1 domain protein repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Sel1
NEGHOLOK_01931	349741.Amuc_0242	2.75e-185	525.0	COG1187@1|root,COG1187@2|Bacteria,46SWQ@74201|Verrucomicrobia,2IUBZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA pseudouridylate synthase	-	-	5.4.99.22	ko:K06178	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NEGHOLOK_01932	349741.Amuc_0243	2.05e-28	102.0	2BJR1@1|root,32E2W@2|Bacteria,46X8H@74201|Verrucomicrobia,2IV0B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01933	349741.Amuc_0244	8.07e-174	484.0	COG0336@1|root,COG0336@2|Bacteria,46SS0@74201|Verrucomicrobia,2ITZV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Guanine-1)-methyltransferase	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NEGHOLOK_01934	349741.Amuc_0245	8.8e-239	656.0	COG1186@1|root,COG1186@2|Bacteria,46SAW@74201|Verrucomicrobia,2ITHK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NEGHOLOK_01935	349741.Amuc_0246	1.66e-87	257.0	COG1321@1|root,COG1321@2|Bacteria	2|Bacteria	K	iron dependent repressor	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
NEGHOLOK_01936	349741.Amuc_0247	0.0	1022.0	COG0539@1|root,COG1185@1|root,COG0539@2|Bacteria,COG1185@2|Bacteria,46SFY@74201|Verrucomicrobia,2ITUF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NEGHOLOK_01937	349741.Amuc_0248	8.55e-135	382.0	COG0778@1|root,COG0778@2|Bacteria,46WEH@74201|Verrucomicrobia	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NEGHOLOK_01938	349741.Amuc_0249	1.75e-110	317.0	COG3153@1|root,COG3153@2|Bacteria,46X3J@74201|Verrucomicrobia,2IUET@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NEGHOLOK_01943	349741.Amuc_0253	8.51e-210	579.0	COG0739@1|root,COG0739@2|Bacteria,46X6I@74201|Verrucomicrobia,2IUPT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NEGHOLOK_01944	349741.Amuc_0254	5.87e-228	627.0	COG1082@1|root,COG1082@2|Bacteria,46SWH@74201|Verrucomicrobia,2ITGF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NEGHOLOK_01945	349741.Amuc_0255	4.13e-183	509.0	COG0413@1|root,COG0413@2|Bacteria,46SPN@74201|Verrucomicrobia,2IU4C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	-	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
NEGHOLOK_01946	349741.Amuc_0256	4.21e-121	345.0	COG0801@1|root,COG0801@2|Bacteria,46T2Z@74201|Verrucomicrobia,2IUKW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	-	-	2.7.6.3	ko:K00950	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HPPK
NEGHOLOK_01947	349741.Amuc_0257	4.14e-175	488.0	COG0289@1|root,COG0289@2|Bacteria,46SPR@74201|Verrucomicrobia,2IU1I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Dihydrodipicolinate reductase, N-terminus	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
NEGHOLOK_01948	349741.Amuc_0258	1.25e-204	566.0	COG0329@1|root,COG0329@2|Bacteria,46SDY@74201|Verrucomicrobia,2ITUK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EM	Dihydrodipicolinate synthetase family	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NEGHOLOK_01950	349741.Amuc_1220	0.0	1711.0	COG3525@1|root,COG3669@1|root,COG3525@2|Bacteria,COG3669@2|Bacteria,46X9G@74201|Verrucomicrobia,2IV3U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	NAGLU,NAGLU_C,NAGLU_N
NEGHOLOK_01952	349741.Amuc_1222	0.0	1200.0	COG1297@1|root,COG1297@2|Bacteria,46TNW@74201|Verrucomicrobia,2IV9P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	OPT oligopeptide transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	OPT
NEGHOLOK_01953	349741.Amuc_1223	5.46e-189	525.0	COG0284@1|root,COG0284@2|Bacteria,46YTH@74201|Verrucomicrobia,2IU2E@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	-	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
NEGHOLOK_01955	349741.Amuc_1225	0.0	1088.0	COG1227@1|root,COG3448@1|root,COG4109@1|root,COG1227@2|Bacteria,COG3448@2|Bacteria,COG4109@2|Bacteria,46UKX@74201|Verrucomicrobia,2ITG8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	DHHA2	-	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
NEGHOLOK_01956	349741.Amuc_1226	1.89e-253	694.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	ko:K18353	ko01502,ko02020,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	Exo_endo_phos
NEGHOLOK_01957	349741.Amuc_1227	8.25e-63	192.0	COG0718@1|root,COG0718@2|Bacteria,46TA9@74201|Verrucomicrobia,2IUTH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	YbaB/EbfC DNA-binding family	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NEGHOLOK_01958	349741.Amuc_1228	0.0	1345.0	COG2812@1|root,COG2812@2|Bacteria,46SGC@74201|Verrucomicrobia,2ITGI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NEGHOLOK_01960	349741.Amuc_1230	4.03e-174	488.0	COG5185@1|root,COG5185@2|Bacteria,46WAF@74201|Verrucomicrobia,2IUTM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	D	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01962	349741.Amuc_1231	1.39e-173	484.0	COG2003@1|root,COG2003@2|Bacteria,46STQ@74201|Verrucomicrobia,2IU7T@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RadC-like JAB domain	-	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NEGHOLOK_01963	349741.Amuc_1232	0.0	976.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,46S7Z@74201|Verrucomicrobia,2ITJV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
NEGHOLOK_01964	349741.Amuc_1233	1.07e-30	108.0	COG0361@1|root,COG0361@2|Bacteria,46T5J@74201|Verrucomicrobia,2IUS9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NEGHOLOK_01965	349741.Amuc_1234	2.79e-97	283.0	COG0102@1|root,COG0102@2|Bacteria,46VEU@74201|Verrucomicrobia,2IUBQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NEGHOLOK_01966	349741.Amuc_1235	1.67e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,46SXI@74201|Verrucomicrobia,2IUDJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein S9/S16	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
NEGHOLOK_01967	349741.Amuc_1236	1.27e-99	289.0	COG1576@1|root,COG1576@2|Bacteria,46VXG@74201|Verrucomicrobia,2IUIQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Predicted SPOUT methyltransferase	-	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NEGHOLOK_01968	349741.Amuc_1237	0.0	984.0	COG0322@1|root,COG0322@2|Bacteria,46SAJ@74201|Verrucomicrobia,2IU0I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	-	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,UVR,UvrC_HhH_N
NEGHOLOK_01969	349741.Amuc_1238	6.34e-183	509.0	COG0811@1|root,COG0811@2|Bacteria,46SY0@74201|Verrucomicrobia,2IU5B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MotA/TolQ/ExbB proton channel family	-	-	-	ko:K03561	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	MotA_ExbB
NEGHOLOK_01970	349741.Amuc_1239	1.08e-97	284.0	COG0848@1|root,COG0848@2|Bacteria,46T1K@74201|Verrucomicrobia,2IUJ8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Biopolymer transport protein ExbD/TolR	-	-	-	ko:K03559	-	-	-	-	ko00000,ko02000	1.A.30.2.1	-	-	ExbD
NEGHOLOK_01971	349741.Amuc_1240	0.0	1523.0	COG0457@1|root,COG1729@1|root,COG0457@2|Bacteria,COG1729@2|Bacteria,46UJD@74201|Verrucomicrobia,2IU8M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_6,TPR_8
NEGHOLOK_01972	349741.Amuc_1241	0.0	1174.0	COG0744@1|root,COG0744@2|Bacteria,46U6K@74201|Verrucomicrobia	74201|Verrucomicrobia	M	PFAM glycosyl transferase family 51	-	-	-	-	-	-	-	-	-	-	-	-	Transgly
NEGHOLOK_01973	349741.Amuc_1242	8.31e-186	516.0	COG0483@1|root,COG0483@2|Bacteria,46T0Z@74201|Verrucomicrobia,2IU5U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
NEGHOLOK_01974	349741.Amuc_1243	1.12e-116	334.0	COG0245@1|root,COG0245@2|Bacteria,46T29@74201|Verrucomicrobia,2IUAJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	4.6.1.12	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	YgbB
NEGHOLOK_01975	349741.Amuc_1244	5.27e-181	503.0	COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NEGHOLOK_01976	349741.Amuc_1245	1.14e-227	626.0	COG1482@1|root,COG1482@2|Bacteria,46SVM@74201|Verrucomicrobia,2IU31@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Phosphomannose isomerase type I	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
NEGHOLOK_01977	349741.Amuc_1246	1.11e-236	658.0	2BHNH@1|root,32BRD@2|Bacteria,46Z4Q@74201|Verrucomicrobia,2IUDY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01978	349741.Amuc_1247	4.15e-296	810.0	COG1757@1|root,COG1757@2|Bacteria,46XTJ@74201|Verrucomicrobia,2IWIX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Na+/H+ antiporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NEGHOLOK_01979	349741.Amuc_1248	2.53e-266	728.0	COG0451@1|root,COG0451@2|Bacteria,46SD9@74201|Verrucomicrobia,2ITY4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	GM	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
NEGHOLOK_01980	349741.Amuc_1249	6.96e-265	724.0	COG1089@1|root,COG1089@2|Bacteria,46SH0@74201|Verrucomicrobia,2ITUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
NEGHOLOK_01981	349741.Amuc_1250	2.56e-271	742.0	COG0505@1|root,COG0505@2|Bacteria,46TDX@74201|Verrucomicrobia,2ITTA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NEGHOLOK_01982	349741.Amuc_1251	0.0	2088.0	COG0458@1|root,COG0458@2|Bacteria,46SBT@74201|Verrucomicrobia,2IU2N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
NEGHOLOK_01983	349741.Amuc_1252	0.0	1413.0	COG3968@1|root,COG3968@2|Bacteria	2|Bacteria	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NEGHOLOK_01984	349741.Amuc_1253	0.0	2927.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,46U9T@74201|Verrucomicrobia,2IWM5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GXGXG motif	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NEGHOLOK_01985	349741.Amuc_1254	0.0	1193.0	COG0706@1|root,COG0706@2|Bacteria,46SHI@74201|Verrucomicrobia,2ITX0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP,YidC_periplas
NEGHOLOK_01986	349741.Amuc_1255	8.98e-59	181.0	COG0759@1|root,COG0759@2|Bacteria,46W3D@74201|Verrucomicrobia,2IW7G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Haemolytic	-	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
NEGHOLOK_01987	349741.Amuc_1256	4.9e-76	227.0	COG0594@1|root,COG0594@2|Bacteria,46WEU@74201|Verrucomicrobia,2IUWY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribonuclease P	-	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NEGHOLOK_01988	349741.Amuc_1257	1.1e-34	118.0	COG0230@1|root,COG0230@2|Bacteria,46WMF@74201|Verrucomicrobia,2IUR8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L34	-	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NEGHOLOK_01989	349741.Amuc_1258	0.0	1405.0	COG3968@1|root,COG3968@2|Bacteria	2|Bacteria	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NEGHOLOK_01990	349741.Amuc_1259	0.0	1477.0	COG1506@1|root,COG2755@1|root,COG1506@2|Bacteria,COG2755@2|Bacteria,46STE@74201|Verrucomicrobia,2IU0N@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2,Peptidase_S9
NEGHOLOK_01991	349741.Amuc_1260	0.0	996.0	COG3408@1|root,COG3408@2|Bacteria,46UWR@74201|Verrucomicrobia,2IVIK@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Trehalase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01992	349741.Amuc_1261	2.45e-211	583.0	COG0676@1|root,COG0676@2|Bacteria,46VKE@74201|Verrucomicrobia,2IUNW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Aldose 1-epimerase	-	-	5.1.3.15	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	-	R02739	RC00563	ko00000,ko00001,ko01000	-	-	-	Aldose_epim
NEGHOLOK_01993	349741.Amuc_1262	3.45e-157	440.0	COG0259@1|root,COG0259@2|Bacteria,46SRQ@74201|Verrucomicrobia,2IU4K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)	-	-	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_phzG_C,Putative_PNPOx
NEGHOLOK_01994	349741.Amuc_1263	1.19e-199	553.0	COG0157@1|root,COG0157@2|Bacteria,46SPY@74201|Verrucomicrobia,2IU3B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Quinolinate phosphoribosyl transferase, N-terminal domain	-	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
NEGHOLOK_01995	349741.Amuc_1264	2.63e-208	576.0	COG0142@1|root,COG0142@2|Bacteria,46S62@74201|Verrucomicrobia,2IU28@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
NEGHOLOK_01996	349741.Amuc_1265	9.55e-242	664.0	COG0136@1|root,COG0136@2|Bacteria,46S74@74201|Verrucomicrobia,2ITM6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NEGHOLOK_01998	349741.Amuc_1267	5.5e-176	489.0	2A8AI@1|root,30XBY@2|Bacteria,46SPH@74201|Verrucomicrobia,2IU9U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_01999	349741.Amuc_1268	0.0	915.0	COG1760@1|root,COG1760@2|Bacteria,46T1Q@74201|Verrucomicrobia,2ITXM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Serine dehydratase alpha chain	-	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha,SDH_beta
NEGHOLOK_02000	349741.Amuc_1269	1.02e-220	609.0	COG0492@1|root,COG0492@2|Bacteria,46SC1@74201|Verrucomicrobia,2ITP4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NEGHOLOK_02001	349741.Amuc_1270	1.96e-224	618.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Lipase_GDSL_2
NEGHOLOK_02002	349741.Amuc_1271	1.33e-133	379.0	COG0454@1|root,COG0454@2|Bacteria	2|Bacteria	K	-acetyltransferase	panZ	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,DUF3616,DUF3749
NEGHOLOK_02007	349741.Amuc_1277	1.2e-167	467.0	COG0084@1|root,COG0084@2|Bacteria,46SRB@74201|Verrucomicrobia,2IUHD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NEGHOLOK_02008	349741.Amuc_1278	0.0	1073.0	COG0475@1|root,COG1226@1|root,COG0475@2|Bacteria,COG1226@2|Bacteria,46YYA@74201|Verrucomicrobia,2ITU7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	TrkA-N domain	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger,TrkA_N
NEGHOLOK_02009	349741.Amuc_1279	2.54e-208	575.0	COG1408@1|root,COG1408@2|Bacteria,46W5P@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NEGHOLOK_02010	349741.Amuc_1280	8.59e-273	745.0	COG2309@1|root,COG2309@2|Bacteria,46SAI@74201|Verrucomicrobia,2ITU9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
NEGHOLOK_02011	349741.Amuc_1281	5.35e-139	392.0	COG0299@1|root,COG0299@2|Bacteria,46SS6@74201|Verrucomicrobia,2IU5Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
NEGHOLOK_02012	349741.Amuc_1282	1.05e-188	525.0	COG0545@1|root,COG0545@2|Bacteria,46VYS@74201|Verrucomicrobia,2IUFJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase	-	-	5.2.1.8	ko:K03773	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,FKBP_N
NEGHOLOK_02021	349741.Amuc_1218	2.69e-256	704.0	COG0337@1|root,COG0337@2|Bacteria,46SRE@74201|Verrucomicrobia,2ITYW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Iron-containing alcohol dehydrogenase	aroB	-	4.2.3.4	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03083	RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NEGHOLOK_02023	349741.Amuc_1216	0.0	870.0	COG0673@1|root,COG0673@2|Bacteria,46TM9@74201|Verrucomicrobia,2ITZ3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NEGHOLOK_02024	349741.Amuc_1215	2.16e-180	500.0	COG3880@1|root,COG3880@2|Bacteria,46SMN@74201|Verrucomicrobia,2IU6R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Cytochrome c7 and related cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_C7
NEGHOLOK_02025	349741.Amuc_1214	0.0	1948.0	COG0243@1|root,COG0437@1|root,COG0243@2|Bacteria,COG0437@2|Bacteria,46S66@74201|Verrucomicrobia,2ITQX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	4Fe-4S dicluster domain	-	-	-	ko:K00184	-	-	-	-	ko00000	5.A.3	-	-	Fer4_7
NEGHOLOK_02027	349741.Amuc_1212	0.0	1357.0	COG1200@1|root,COG1200@2|Bacteria,46TTC@74201|Verrucomicrobia,2ITXG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RecG wedge domain	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NEGHOLOK_02028	349741.Amuc_1211	1.64e-165	462.0	COG5632@1|root,COG5632@2|Bacteria,46VKP@74201|Verrucomicrobia,2IU5K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM N-acetylmuramoyl-L-alanine amidase family 2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NEGHOLOK_02029	349741.Amuc_1210	0.0	1293.0	COG1274@1|root,COG1274@2|Bacteria,46UB8@74201|Verrucomicrobia,2ITQG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
NEGHOLOK_02031	349741.Amuc_1208	5.04e-82	243.0	COG0736@1|root,COG0736@2|Bacteria,46T5U@74201|Verrucomicrobia,2IUTE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	4'-phosphopantetheinyl transferase superfamily	acpS	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NEGHOLOK_02032	349741.Amuc_1207	1.62e-172	481.0	COG0854@1|root,COG0854@2|Bacteria,46SJT@74201|Verrucomicrobia,2ITP1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate	pdxJ	-	2.6.99.2	ko:K03474	ko00750,ko01100,map00750,map01100	M00124	R05838	RC01476	ko00000,ko00001,ko00002,ko01000	-	-	-	PdxJ
NEGHOLOK_02033	349741.Amuc_1206	0.0	1020.0	COG0138@1|root,COG0138@2|Bacteria,46S5H@74201|Verrucomicrobia,2ITYZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	AICARFT/IMPCHase bienzyme	-	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
NEGHOLOK_02034	349741.Amuc_1205	7.49e-95	277.0	COG0359@1|root,COG0359@2|Bacteria,46SYE@74201|Verrucomicrobia,2IUF8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal protein L9, N-terminal domain	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NEGHOLOK_02035	349741.Amuc_1204	1.05e-226	625.0	COG0598@1|root,COG0598@2|Bacteria,46VYH@74201|Verrucomicrobia,2IU92@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	CorA-like Mg2+ transporter protein	-	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NEGHOLOK_02036	349741.Amuc_1203	9.16e-209	577.0	COG0548@1|root,COG0548@2|Bacteria,46SH9@74201|Verrucomicrobia,2ITVB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Amino acid kinase family	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
NEGHOLOK_02037	226186.BT_0869	2.84e-18	81.3	2DQ3B@1|root,334JY@2|Bacteria,4P6N1@976|Bacteroidetes,2G2BH@200643|Bacteroidia,4AVVZ@815|Bacteroidaceae	976|Bacteroidetes	S	Lipocalin-like	-	-	-	-	-	-	-	-	-	-	-	-	Lipocalin_3
NEGHOLOK_02039	349741.Amuc_1200	8.77e-239	657.0	COG0310@1|root,COG0310@2|Bacteria	2|Bacteria	P	cobalt ion transport	cbiM	-	-	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	iAF987.Gmet_2441	CbiM,PDGLE
NEGHOLOK_02040	349741.Amuc_1199	1.99e-194	539.0	COG0619@1|root,COG0619@2|Bacteria	2|Bacteria	P	transmembrane transporter activity	cbiQ	GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351	-	ko:K02007,ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NEGHOLOK_02041	349741.Amuc_1198	4.82e-179	499.0	COG1122@1|root,COG1122@2|Bacteria	2|Bacteria	P	ATPase activity	cbiO	-	-	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	M00245,M00246,M00581,M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23,3.A.1.25,3.A.1.25.1,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NEGHOLOK_02042	349741.Amuc_1197	0.0	1290.0	COG1199@1|root,COG1199@2|Bacteria,46SCS@74201|Verrucomicrobia,2ITJT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	HELICc2	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
NEGHOLOK_02044	349741.Amuc_1195	1.42e-209	578.0	COG1947@1|root,COG1947@2|Bacteria,46SV6@74201|Verrucomicrobia,2IU5F@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	GHMP kinases N terminal domain	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NEGHOLOK_02045	349741.Amuc_1194	0.0	1217.0	COG0187@1|root,COG0187@2|Bacteria,46UY6@74201|Verrucomicrobia,2ITJR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	TopoisomeraseII	-	-	-	ko:K02622	-	-	-	-	ko00000,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NEGHOLOK_02046	349741.Amuc_1193	1.06e-173	484.0	COG0020@1|root,COG0020@2|Bacteria,46SMY@74201|Verrucomicrobia,2IU5V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NEGHOLOK_02047	349741.Amuc_1192	2.41e-259	710.0	COG0836@1|root,COG0836@2|Bacteria,46SAQ@74201|Verrucomicrobia,2ITXZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Nucleotidyl transferase	-	-	2.7.7.13	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase
NEGHOLOK_02048	349741.Amuc_1191	2.13e-96	280.0	COG0816@1|root,COG0816@2|Bacteria,46T51@74201|Verrucomicrobia,2IUHN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Likely ribonuclease with RNase H fold.	-	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
NEGHOLOK_02049	349741.Amuc_1190	3.85e-235	647.0	COG0604@1|root,COG0604@2|Bacteria,46UF3@74201|Verrucomicrobia,2ITYR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NEGHOLOK_02050	349741.Amuc_1189	1.45e-55	173.0	COG0227@1|root,COG0227@2|Bacteria,46TBF@74201|Verrucomicrobia,2IUUU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NEGHOLOK_02051	349741.Amuc_1188	1.04e-49	157.0	2EIJD@1|root,33CAP@2|Bacteria,46WH7@74201|Verrucomicrobia,2IW3W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02052	349741.Amuc_1187	0.0	1062.0	COG1501@1|root,COG1501@2|Bacteria,46UJE@74201|Verrucomicrobia,2IUGJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha galactosidase A	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	He_PIG_assoc,Melibiase_2
NEGHOLOK_02053	349741.Amuc_1186	1.84e-221	613.0	COG1477@1|root,COG1477@2|Bacteria,46V70@74201|Verrucomicrobia,2IUN9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NEGHOLOK_02054	349741.Amuc_1185	0.0	1089.0	COG0436@1|root,COG0436@2|Bacteria,46TMR@74201|Verrucomicrobia,2ITKU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
NEGHOLOK_02055	349741.Amuc_1184	4.6e-305	832.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,2ITUV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NEGHOLOK_02056	349741.Amuc_1183	1.04e-78	234.0	COG2919@1|root,COG2919@2|Bacteria	2|Bacteria	D	cell cycle	divIC	-	-	ko:K05589,ko:K13052	-	-	-	-	ko00000,ko03036	-	-	-	DivIC
NEGHOLOK_02058	349741.Amuc_1182	0.0	962.0	COG3119@1|root,COG3119@2|Bacteria,46TNU@74201|Verrucomicrobia,2IUAA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NEGHOLOK_02060	349741.Amuc_1180	9.64e-153	430.0	COG2186@1|root,COG2186@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NEGHOLOK_02061	349741.Amuc_1179	2.92e-189	525.0	COG1119@1|root,COG1119@2|Bacteria,46SN3@74201|Verrucomicrobia,2IVY6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NEGHOLOK_02062	349741.Amuc_1178	1.35e-236	650.0	COG0059@1|root,COG0059@2|Bacteria,46SI2@74201|Verrucomicrobia,2ITY3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	-	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NEGHOLOK_02063	349741.Amuc_1177	1.03e-121	347.0	COG3040@1|root,COG3040@2|Bacteria,46WHH@74201|Verrucomicrobia,2IUQU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Lipocalin-like domain	-	-	-	ko:K03098	-	-	-	-	ko00000,ko04147	-	-	-	Lipocalin_2
NEGHOLOK_02064	349741.Amuc_1176	2.29e-208	578.0	COG1090@1|root,COG1090@2|Bacteria,46V7D@74201|Verrucomicrobia,2IUFW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
NEGHOLOK_02065	349741.Amuc_1175	3.48e-203	568.0	COG0330@1|root,COG0330@2|Bacteria	2|Bacteria	O	stress-induced mitochondrial fusion	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
NEGHOLOK_02067	349741.Amuc_1173	4.01e-240	659.0	COG0399@1|root,COG0399@2|Bacteria	2|Bacteria	E	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5,Cys_Met_Meta_PP,DegT_DnrJ_EryC1
NEGHOLOK_02069	349741.Amuc_1171	4.24e-296	807.0	COG2311@1|root,COG2311@2|Bacteria,46VK7@74201|Verrucomicrobia,2IUSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF1624,DUF418
NEGHOLOK_02070	349741.Amuc_1170	2.12e-237	654.0	COG0714@1|root,COG0714@2|Bacteria,46UXC@74201|Verrucomicrobia,2ITIT@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NEGHOLOK_02071	349741.Amuc_1169	0.0	1050.0	2A55Z@1|root,30TUT@2|Bacteria,46VF8@74201|Verrucomicrobia,2IUQ6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02072	349741.Amuc_1168	1.78e-241	663.0	COG1131@1|root,COG1131@2|Bacteria,46UCK@74201|Verrucomicrobia,2IU4B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NEGHOLOK_02073	349741.Amuc_1167	0.0	907.0	COG1277@1|root,COG1277@2|Bacteria,46VD7@74201|Verrucomicrobia,2IUUX@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02074	349741.Amuc_1166	1.58e-205	568.0	COG1721@1|root,COG1721@2|Bacteria,46UAR@74201|Verrucomicrobia,2IUE4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NEGHOLOK_02075	349741.Amuc_1165	0.0	1139.0	29WV1@1|root,30IGI@2|Bacteria,46UUV@74201|Verrucomicrobia,2IUAB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Aerotolerance regulator N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	BatA
NEGHOLOK_02076	349741.Amuc_1164	0.0	1677.0	COG2304@1|root,COG5426@1|root,COG2304@2|Bacteria,COG5426@2|Bacteria,46TXD@74201|Verrucomicrobia,2ITGB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	von Willebrand factor type A domain	-	-	-	-	-	-	-	-	-	-	-	-	VWA,VWA_3
NEGHOLOK_02077	349741.Amuc_1163	2.53e-293	802.0	2F3HC@1|root,33WAZ@2|Bacteria,46VF5@74201|Verrucomicrobia,2IUSV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02078	349741.Amuc_1162	4.05e-259	709.0	COG2008@1|root,COG2008@2|Bacteria,46SB9@74201|Verrucomicrobia,2IW5S@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NEGHOLOK_02079	349741.Amuc_1161	6.71e-90	265.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF3967,MerR_1
NEGHOLOK_02080	349741.Amuc_1160	2.81e-280	765.0	COG0667@1|root,COG0667@2|Bacteria,46SPV@74201|Verrucomicrobia,2ITQC@203494|Verrucomicrobiae	2|Bacteria	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,TAT_signal
NEGHOLOK_02081	349741.Amuc_1159	0.0	1464.0	COG0515@1|root,COG3063@1|root,COG0515@2|Bacteria,COG3063@2|Bacteria,46UAE@74201|Verrucomicrobia,2IV44@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase,TPR_12,WD40
NEGHOLOK_02082	349741.Amuc_1158	3.34e-139	393.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4_2
NEGHOLOK_02083	349741.Amuc_1157	4.85e-195	541.0	COG0491@1|root,COG0491@2|Bacteria,46VU3@74201|Verrucomicrobia,2IW2R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NEGHOLOK_02085	349741.Amuc_1155	2.06e-232	640.0	COG1262@1|root,COG1262@2|Bacteria	2|Bacteria	T	PFAM Formylglycine-generating sulfatase enzyme	-	-	2.7.11.1	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	FGE-sulfatase,PEGA,Pkinase
NEGHOLOK_02086	349741.Amuc_1154	3.88e-263	721.0	COG0642@1|root,COG2205@2|Bacteria,46UHY@74201|Verrucomicrobia,2ITGS@203494|Verrucomicrobiae	349741.Amuc_1154|-	T	Osmosensitive K+ channel His kinase sensor domain	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	-
NEGHOLOK_02088	349741.Amuc_1153	2.54e-132	375.0	COG2156@1|root,COG2156@2|Bacteria,46SYC@74201|Verrucomicrobia,2IVFX@203494|Verrucomicrobiae	74201|Verrucomicrobia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
NEGHOLOK_02089	349741.Amuc_1152	0.0	1263.0	COG2216@1|root,COG2216@2|Bacteria,46SEM@74201|Verrucomicrobia,2ITIQ@203494|Verrucomicrobiae	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	iSB619.SA_RS00495	E1-E2_ATPase,Hydrolase
NEGHOLOK_02090	349741.Amuc_1151	0.0	1115.0	COG2060@1|root,COG2060@2|Bacteria,46S9Y@74201|Verrucomicrobia,2ITVE@203494|Verrucomicrobiae	74201|Verrucomicrobia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
NEGHOLOK_02091	349741.Amuc_1143	4.41e-13	68.6	COG3209@1|root,COG3209@2|Bacteria,46TI5@74201|Verrucomicrobia,2IVP8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	PFAM YD repeat-containing protein	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclea_NS_2,RHS_repeat
NEGHOLOK_02094	349741.Amuc_0890	0.0	1930.0	COG0841@1|root,COG0841@2|Bacteria,46SBF@74201|Verrucomicrobia,2IWNC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	AcrB/AcrD/AcrF family	-	-	-	ko:K18095	ko01501,ko02020,map01501,map02020	M00643	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2.21,2.A.6.2.24	-	-	ACR_tran
NEGHOLOK_02095	349741.Amuc_0889	1.17e-241	667.0	COG0845@1|root,COG0845@2|Bacteria,46SB8@74201|Verrucomicrobia,2IU1C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Biotin-lipoyl like	-	-	-	ko:K18094	ko01501,ko02020,map01501,map02020	M00643	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	2.A.6.2.21,2.A.6.2.24,8.A.1	-	-	HlyD,HlyD_D23
NEGHOLOK_02096	349741.Amuc_0888	4.49e-191	530.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,MerR_1
NEGHOLOK_02097	349741.Amuc_0887	1.13e-221	611.0	COG1071@1|root,COG1071@2|Bacteria,46UAY@74201|Verrucomicrobia,2ITWI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Dehydrogenase E1 component	-	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
NEGHOLOK_02098	349741.Amuc_0886	9.47e-236	648.0	COG0022@1|root,COG0022@2|Bacteria,46UID@74201|Verrucomicrobia,2ITK5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Transketolase, pyrimidine binding domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NEGHOLOK_02099	349741.Amuc_0885	1.63e-298	815.0	COG0508@1|root,COG0508@2|Bacteria,46UHU@74201|Verrucomicrobia,2ITVD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
NEGHOLOK_02100	349741.Amuc_0884	3.32e-206	570.0	COG3494@1|root,COG3494@2|Bacteria,46SJ6@74201|Verrucomicrobia,2IU0K@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1009)	-	-	-	ko:K09949	-	-	-	-	ko00000	-	-	-	DUF1009
NEGHOLOK_02103	349741.Amuc_0881	8.73e-87	255.0	2DTWY@1|root,33N1Q@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NEGHOLOK_02104	349741.Amuc_0880	5.6e-171	477.0	COG2315@1|root,COG2315@2|Bacteria	2|Bacteria	V	Protein conserved in bacteria	yyaQ	-	-	-	-	-	-	-	-	-	-	-	YjbR
NEGHOLOK_02105	349741.Amuc_0879	8.39e-191	529.0	COG1922@1|root,COG1922@2|Bacteria,46VQJ@74201|Verrucomicrobia,2IUM7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase WecB/TagA/CpsF family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tran_WecB
NEGHOLOK_02106	349741.Amuc_0878	1.06e-189	526.0	COG1235@1|root,COG1235@2|Bacteria,46SRW@74201|Verrucomicrobia,2IU7C@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metallo-beta-lactamase superfamily	-	-	3.1.4.55	ko:K06167	ko00440,map00440	-	R10205	RC00296	ko00000,ko00001,ko01000	-	-	-	Lactamase_B_2
NEGHOLOK_02107	349741.Amuc_0877	0.0	1030.0	COG0497@1|root,COG0497@2|Bacteria,46SGB@74201|Verrucomicrobia,2IU0W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
NEGHOLOK_02108	349741.Amuc_0876	0.0	1422.0	COG2217@1|root,COG2217@2|Bacteria,46S9Z@74201|Verrucomicrobia,2ITMQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	E1-E2 ATPase	-	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,Hydrolase,YHS
NEGHOLOK_02109	349741.Amuc_0875	2.85e-245	671.0	COG2273@1|root,COG2273@2|Bacteria,46XEF@74201|Verrucomicrobia,2IVNG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_16
NEGHOLOK_02110	349741.Amuc_0874	9.29e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,46SQH@74201|Verrucomicrobia,2IU7M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Elongation factor P (EF-P) OB domain	-	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NEGHOLOK_02111	349741.Amuc_0873	1.2e-105	305.0	COG4747@1|root,COG4747@2|Bacteria,46SXP@74201|Verrucomicrobia,2IUP5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02112	349741.Amuc_0872	4.8e-313	851.0	COG4992@1|root,COG4992@2|Bacteria,46SUV@74201|Verrucomicrobia,2ITW4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class-III	-	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NEGHOLOK_02113	349741.Amuc_0871	3.06e-85	252.0	COG1970@1|root,COG1970@2|Bacteria,46VW8@74201|Verrucomicrobia,2IUX6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Large-conductance mechanosensitive channel, MscL	-	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
NEGHOLOK_02114	349741.Amuc_0870	8.34e-277	756.0	COG1785@1|root,COG1785@2|Bacteria,46X6X@74201|Verrucomicrobia,2IUSG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Alkaline phosphatase homologues	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	Alk_phosphatase
NEGHOLOK_02115	349741.Amuc_0869	4.93e-286	781.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NEGHOLOK_02116	349741.Amuc_0868	0.0	1120.0	COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_02117	349741.Amuc_0867	2.54e-267	733.0	COG1363@1|root,COG1363@2|Bacteria,46XAY@74201|Verrucomicrobia,2IV87@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NEGHOLOK_02119	349741.Amuc_0865	1.96e-121	347.0	COG1592@1|root,COG1592@2|Bacteria	2|Bacteria	C	Rubrerythrin	ngr	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Rubrerythrin
NEGHOLOK_02121	349741.Amuc_0864	0.0	1130.0	COG2194@1|root,COG2194@2|Bacteria,46XK1@74201|Verrucomicrobia,2IW42@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Domain of unknown function (DUF1705)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1705,Sulfatase
NEGHOLOK_02122	349741.Amuc_0863	0.0	1548.0	COG4225@1|root,COG4225@2|Bacteria,46UYE@74201|Verrucomicrobia,2IVRC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl Hydrolase Family 88	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_88
NEGHOLOK_02123	349741.Amuc_0862	0.0	1430.0	COG1328@1|root,COG1328@2|Bacteria,46TE5@74201|Verrucomicrobia,2IV27@203494|Verrucomicrobiae	203494|Verrucomicrobiae	F	Anaerobic ribonucleoside-triphosphate reductase	-	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	NRDD
NEGHOLOK_02124	349741.Amuc_0861	3.8e-43	140.0	COG1328@1|root,COG1328@2|Bacteria	2|Bacteria	F	CTP reductase activity	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
NEGHOLOK_02125	349741.Amuc_0860	1.52e-188	522.0	COG1180@1|root,COG1180@2|Bacteria,46W66@74201|Verrucomicrobia,2IVWH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Radical SAM superfamily	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Radical_SAM
NEGHOLOK_02126	349741.Amuc_0859	0.0	1076.0	COG0471@1|root,COG0471@2|Bacteria,46XAZ@74201|Verrucomicrobia,2IV8A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Citrate transporter	-	-	-	ko:K14445	-	-	-	-	ko00000,ko02000	2.A.47.1	-	-	Na_sulph_symp
NEGHOLOK_02127	349741.Amuc_0858	0.0	940.0	COG4191@1|root,COG4191@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,cNMP_binding
NEGHOLOK_02128	349741.Amuc_0857	1.33e-110	318.0	COG0784@1|root,COG0784@2|Bacteria,46XJY@74201|Verrucomicrobia,2IW3P@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
NEGHOLOK_02129	349741.Amuc_0856	0.0	1025.0	COG0569@1|root,COG2985@1|root,COG0569@2|Bacteria,COG2985@2|Bacteria,46YYG@74201|Verrucomicrobia,2IU9A@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Predicted Permease Membrane Region	-	-	-	ko:K07085	-	-	-	-	ko00000	2.A.81	-	-	Asp-Al_Ex,TrkA_C
NEGHOLOK_02130	349741.Amuc_0855	0.0	1444.0	COG3345@1|root,COG3345@2|Bacteria,46UG8@74201|Verrucomicrobia,2IVJR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NEGHOLOK_02131	349741.Amuc_0854	7.36e-55	171.0	COG0776@1|root,COG0776@2|Bacteria	2|Bacteria	L	regulation of translation	himA	-	-	ko:K03530,ko:K04764,ko:K05788	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NEGHOLOK_02132	349741.Amuc_0853	0.0	988.0	2BTJH@1|root,32NS3@2|Bacteria,46XQC@74201|Verrucomicrobia,2IWD7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02135	349741.Amuc_0850	6.96e-305	830.0	COG2265@1|root,COG2265@2|Bacteria,46SYJ@74201|Verrucomicrobia,2ITST@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA (Uracil-5-)-methyltransferase	-	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NEGHOLOK_02136	349741.Amuc_0849	0.0	901.0	COG0621@1|root,COG0621@2|Bacteria,46S6B@74201|Verrucomicrobia,2ITRH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NEGHOLOK_02137	349741.Amuc_0848	0.0	1281.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,46T3W@74201|Verrucomicrobia,2IUFR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Competence protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NEGHOLOK_02138	349741.Amuc_0847	3.29e-258	707.0	COG3481@1|root,COG3481@2|Bacteria,46SYB@74201|Verrucomicrobia,2ITKE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD
NEGHOLOK_02139	349741.Amuc_0846	0.0	1462.0	COG3669@1|root,COG3669@2|Bacteria,46TW6@74201|Verrucomicrobia,2IVJY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,F5_F8_type_C
NEGHOLOK_02140	349741.Amuc_0845	4.2e-204	564.0	COG0648@1|root,COG0648@2|Bacteria,46VWJ@74201|Verrucomicrobia	74201|Verrucomicrobia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NEGHOLOK_02141	349741.Amuc_0844	2.46e-307	838.0	COG0148@1|root,COG0148@2|Bacteria,46S7N@74201|Verrucomicrobia,2ITUV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	-	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NEGHOLOK_02142	349741.Amuc_0843	0.0	996.0	2BTJC@1|root,32NRX@2|Bacteria,46XRE@74201|Verrucomicrobia,2IWF2@203494|Verrucomicrobiae	349741.Amuc_0843|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02143	349741.Amuc_0842	1.24e-163	457.0	COG4279@1|root,COG4279@2|Bacteria,46V8E@74201|Verrucomicrobia,2IUH9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	SWIM zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	SWIM
NEGHOLOK_02144	349741.Amuc_0841	0.0	906.0	COG0165@1|root,COG0165@2|Bacteria,46SCX@74201|Verrucomicrobia,2ITKH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NEGHOLOK_02145	349741.Amuc_0840	0.0	1056.0	COG0659@1|root,COG0659@2|Bacteria,46UA5@74201|Verrucomicrobia,2IWMC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Sulfate permease family	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
NEGHOLOK_02146	349741.Amuc_0839	7.2e-125	355.0	28XDJ@1|root,2ZJBA@2|Bacteria,46WSJ@74201|Verrucomicrobia,2IUQ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02147	349741.Amuc_0838	1.04e-109	316.0	COG1327@1|root,COG1327@2|Bacteria,46TAA@74201|Verrucomicrobia,2IU77@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NEGHOLOK_02148	349741.Amuc_0837	0.0	1011.0	2DG3X@1|root,2ZUD5@2|Bacteria	2|Bacteria	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
NEGHOLOK_02149	349741.Amuc_1777	8.51e-42	151.0	COG0457@1|root,COG2304@1|root,COG0457@2|Bacteria,COG2304@2|Bacteria,46U4T@74201|Verrucomicrobia,2IWN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	VWA_2
NEGHOLOK_02150	349741.Amuc_1776	0.0	1559.0	COG0457@1|root,COG0457@2|Bacteria,46SZM@74201|Verrucomicrobia,2IUFN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Oxygen tolerance	-	-	-	-	-	-	-	-	-	-	-	-	BatD
NEGHOLOK_02151	349741.Amuc_1775	1.36e-204	565.0	COG0656@1|root,COG0656@2|Bacteria	2|Bacteria	S	aldo-keto reductase (NADP) activity	yeaE	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NEGHOLOK_02152	349741.Amuc_1774	0.0	1080.0	COG0423@1|root,COG0423@2|Bacteria,46TEV@74201|Verrucomicrobia,2ITMG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Anticodon binding domain	-	-	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NEGHOLOK_02153	349741.Amuc_1773	8.72e-155	434.0	COG1434@1|root,COG1434@2|Bacteria,46XE9@74201|Verrucomicrobia,2IVN5@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NEGHOLOK_02154	349741.Amuc_1772	9.2e-208	572.0	COG1266@1|root,COG1266@2|Bacteria,46VN3@74201|Verrucomicrobia,2IU8B@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NEGHOLOK_02155	349741.Amuc_1771	3.2e-286	781.0	COG0436@1|root,COG0436@2|Bacteria,46SFZ@74201|Verrucomicrobia,2ITGM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Cys/Met metabolism PLP-dependent enzyme	-	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_02156	349741.Amuc_1770	8.26e-106	306.0	COG1522@1|root,COG1522@2|Bacteria,46VEI@74201|Verrucomicrobia,2IU8W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
NEGHOLOK_02157	349741.Amuc_1769	0.0	2334.0	COG0553@1|root,COG0553@2|Bacteria,46YZ0@74201|Verrucomicrobia,2ITIC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
NEGHOLOK_02158	349741.Amuc_1768	8.46e-84	247.0	COG2967@1|root,COG2967@2|Bacteria,46T44@74201|Verrucomicrobia,2IUUM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	ApaG domain	-	-	-	ko:K06195	-	-	-	-	ko00000	-	-	-	DUF525
NEGHOLOK_02159	349741.Amuc_1767	7.47e-203	562.0	2F4CA@1|root,33X2V@2|Bacteria,46VIX@74201|Verrucomicrobia,2IUA1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02160	349741.Amuc_1766	0.0	1015.0	COG1215@1|root,COG1215@2|Bacteria,46SF7@74201|Verrucomicrobia,2ITZU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
NEGHOLOK_02161	349741.Amuc_1765	3.67e-193	537.0	COG1376@1|root,COG1376@2|Bacteria,46VQZ@74201|Verrucomicrobia,2IUGD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
NEGHOLOK_02162	349741.Amuc_1764	1.88e-135	383.0	COG1678@1|root,COG1678@2|Bacteria,46VUF@74201|Verrucomicrobia,2IUUZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	K	Uncharacterized ACR, COG1678	-	-	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
NEGHOLOK_02163	349741.Amuc_1763	1.02e-163	458.0	COG0325@1|root,COG0325@2|Bacteria,46SV2@74201|Verrucomicrobia,2IU7Y@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NEGHOLOK_02164	349741.Amuc_1762	0.0	1097.0	COG0699@1|root,COG0699@2|Bacteria,46W58@74201|Verrucomicrobia,2IUZ4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	50S ribosome-binding GTPase	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
NEGHOLOK_02165	349741.Amuc_1761	3.48e-140	395.0	COG0212@1|root,COG0212@2|Bacteria,46T35@74201|Verrucomicrobia,2IUUD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	5-formyltetrahydrofolate cyclo-ligase family	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
NEGHOLOK_02166	349741.Amuc_1760	8.83e-209	577.0	COG1131@1|root,COG1131@2|Bacteria,46SHV@74201|Verrucomicrobia,2ITWN@203494|Verrucomicrobiae	203494|Verrucomicrobiae	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NEGHOLOK_02167	349741.Amuc_1759	0.0	939.0	COG0624@1|root,COG0624@2|Bacteria,46UH8@74201|Verrucomicrobia,2ITIW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NEGHOLOK_02168	349741.Amuc_1758	3.12e-223	616.0	COG1493@1|root,COG1493@2|Bacteria,46S64@74201|Verrucomicrobia,2ITXV@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NEGHOLOK_02169	349741.Amuc_1757	8.72e-53	166.0	COG1925@1|root,COG1925@2|Bacteria,46T6C@74201|Verrucomicrobia,2IUM2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	PTS HPr component phosphorylation site	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NEGHOLOK_02170	349741.Amuc_1756	0.0	1154.0	COG1080@1|root,COG1080@2|Bacteria,46TX4@74201|Verrucomicrobia,2ITIJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9	ko:K08483	ko02060,map02060	-	-	-	ko00000,ko00001,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NEGHOLOK_02171	349741.Amuc_1755	0.0	1141.0	COG3119@1|root,COG3119@2|Bacteria,46SHT@74201|Verrucomicrobia,2IUAW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NEGHOLOK_02172	349741.Amuc_1754	1.64e-223	616.0	COG0078@1|root,COG0078@2|Bacteria,46SA5@74201|Verrucomicrobia,2IU2R@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	-	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NEGHOLOK_02173	349741.Amuc_1753	5.06e-94	274.0	COG2166@1|root,COG2166@2|Bacteria,46XA6@74201|Verrucomicrobia,2IUGW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Fe-S metabolism associated domain	-	-	-	ko:K02426	-	-	-	-	ko00000	-	-	-	SufE
NEGHOLOK_02175	349741.Amuc_1751	0.0	1412.0	COG0296@1|root,COG0296@2|Bacteria,46SH5@74201|Verrucomicrobia,2ITSF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha amylase, C-terminal all-beta domain	-	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NEGHOLOK_02176	349741.Amuc_1750	1.97e-260	711.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NEGHOLOK_02177	349741.Amuc_1749	0.0	1199.0	COG0079@1|root,COG1213@1|root,COG0079@2|Bacteria,COG1213@2|Bacteria	2|Bacteria	M	nucleotidyl transferase	cobD	-	2.6.1.9,2.7.7.74,4.1.1.81	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530,R09669	RC00002,RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,NTP_transf_3
NEGHOLOK_02178	411477.PARMER_01056	2.13e-95	292.0	COG2423@1|root,COG2423@2|Bacteria,4PJ6G@976|Bacteroidetes,2FR7I@200643|Bacteroidia,23165@171551|Porphyromonadaceae	976|Bacteroidetes	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
NEGHOLOK_02179	349741.Amuc_1747	0.0	881.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,46UQX@74201|Verrucomicrobia,2IW4Z@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Oxidoreductase family, NAD-binding Rossmann fold	-	-	2.7.7.15	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	M00090	R01890,R02590	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NEGHOLOK_02180	349741.Amuc_1746	2.54e-226	623.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NEGHOLOK_02181	349741.Amuc_1744	2.33e-130	371.0	COG1729@1|root,COG1729@2|Bacteria	2|Bacteria	S	protein trimerization	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_2,TPR_6,TPR_8
NEGHOLOK_02183	349741.Amuc_1742	1.84e-183	509.0	COG4106@1|root,COG4106@2|Bacteria	2|Bacteria	FG	trans-aconitate 2-methyltransferase activity	-	-	2.1.1.144,2.1.1.197	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	M00572	R09543	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
NEGHOLOK_02184	349741.Amuc_1741	0.0	914.0	COG4284@1|root,COG4284@2|Bacteria,46YX5@74201|Verrucomicrobia,2ITK7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	UTP--glucose-1-phosphate uridylyltransferase	-	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPGP
NEGHOLOK_02185	349741.Amuc_1740	1.67e-123	352.0	2B2U2@1|root,31VEM@2|Bacteria,46X86@74201|Verrucomicrobia,2IUZ0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02186	349741.Amuc_1739	3.09e-61	190.0	COG1186@1|root,COG1186@2|Bacteria,46T84@74201|Verrucomicrobia,2IUUG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RF-1 domain	-	-	-	-	-	-	-	-	-	-	-	-	RF-1
NEGHOLOK_02187	349741.Amuc_1738	5.73e-120	346.0	COG0669@1|root,COG0669@2|Bacteria,46SUT@74201|Verrucomicrobia,2IUBC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NEGHOLOK_02188	349741.Amuc_1737	1.28e-276	757.0	COG0743@1|root,COG0743@2|Bacteria,46S90@74201|Verrucomicrobia,2ITI1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	-	DXPR_C,DXP_redisom_C,DXP_reductoisom
NEGHOLOK_02189	349741.Amuc_1736	4.43e-291	795.0	COG2311@1|root,COG2311@2|Bacteria,46VK7@74201|Verrucomicrobia,2IUSC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF418)	-	-	-	ko:K07148	-	-	-	-	ko00000	-	-	-	DUF1624,DUF418
NEGHOLOK_02190	272942.RCAP_rcc01326	9.6e-79	262.0	COG0732@1|root,COG0732@2|Bacteria,1MXVH@1224|Proteobacteria,2U1BF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NEGHOLOK_02191	1160721.RBI_I01528	6.63e-144	411.0	COG0582@1|root,COG0582@2|Bacteria,1UJT9@1239|Firmicutes,24EEC@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NEGHOLOK_02192	1341157.RF007C_13570	2.92e-163	479.0	COG0732@1|root,COG0732@2|Bacteria,1TT1D@1239|Firmicutes,24A13@186801|Clostridia,3WKZ8@541000|Ruminococcaceae	186801|Clostridia	V	Type I restriction modification DNA specificity domain	-	-	3.1.21.3	ko:K01154	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Methylase_S
NEGHOLOK_02193	1408322.JHYK01000001_gene1445	8.71e-301	825.0	COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,247RY@186801|Clostridia,27KD4@186928|unclassified Lachnospiraceae	186801|Clostridia	V	N-6 DNA Methylase	hsdM	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HsdM_N,Methylase_S,N6_Mtase
NEGHOLOK_02194	888727.HMPREF9092_0521	0.0	1216.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia	186801|Clostridia	L	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	hsdR	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF4145,EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
NEGHOLOK_02196	349741.Amuc_1733	3.29e-146	412.0	COG0290@1|root,COG0290@2|Bacteria,46SU6@74201|Verrucomicrobia,2IUB3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	-	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NEGHOLOK_02197	349741.Amuc_1732	0.0	1274.0	COG0441@1|root,COG0441@2|Bacteria,46S5A@74201|Verrucomicrobia,2ITM8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
NEGHOLOK_02199	349741.Amuc_1730	4.89e-237	652.0	COG0113@1|root,COG0113@2|Bacteria,46S91@74201|Verrucomicrobia,2ITPG@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Delta-aminolevulinic acid dehydratase	-	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
NEGHOLOK_02201	349741.Amuc_1728	2.04e-160	450.0	COG0745@1|root,COG0745@2|Bacteria,46UZH@74201|Verrucomicrobia,2IVRM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NEGHOLOK_02202	349741.Amuc_1727	0.0	1052.0	COG0642@1|root,COG2205@2|Bacteria,46Z6V@74201|Verrucomicrobia,2IWPY@203494|Verrucomicrobiae	203494|Verrucomicrobiae	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NEGHOLOK_02203	349741.Amuc_1726	5.99e-231	636.0	COG0451@1|root,COG0451@2|Bacteria,46TPV@74201|Verrucomicrobia,2IWKZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	3-beta hydroxysteroid dehydrogenase/isomerase family	-	-	4.1.1.35	ko:K08678	ko00520,ko01100,map00520,map01100	M00361	R01384	RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NEGHOLOK_02204	349741.Amuc_1725	5.27e-184	511.0	COG3884@1|root,COG3884@2|Bacteria,46WFX@74201|Verrucomicrobia	74201|Verrucomicrobia	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
NEGHOLOK_02205	349741.Amuc_1828	0.0	2050.0	COG2982@1|root,COG2982@2|Bacteria,46SSM@74201|Verrucomicrobia,2IUJJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	AsmA-like C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	AsmA_2
NEGHOLOK_02206	349741.Amuc_1827	3.05e-170	474.0	COG1741@1|root,COG1741@2|Bacteria,46SRJ@74201|Verrucomicrobia,2IU6M@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Pirin	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin
NEGHOLOK_02208	349741.Amuc_1825	2.4e-172	481.0	COG1189@1|root,COG1189@2|Bacteria,46SM8@74201|Verrucomicrobia,2ITPM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NEGHOLOK_02211	349741.Amuc_1822	1.42e-215	595.0	COG0363@1|root,COG0363@2|Bacteria,46TGA@74201|Verrucomicrobia,2IU20@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso,PIG-L
NEGHOLOK_02212	349741.Amuc_1821	6.71e-285	778.0	COG1092@1|root,COG1092@2|Bacteria,46SJ5@74201|Verrucomicrobia,2ITMI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	S-adenosylmethionine-dependent methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NEGHOLOK_02213	349741.Amuc_1820	4.7e-57	177.0	COG1837@1|root,COG1837@2|Bacteria,46X7A@74201|Verrucomicrobia,2IUUH@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	KH domain	-	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NEGHOLOK_02214	349741.Amuc_1819	0.0	1663.0	28I8X@1|root,2Z8BQ@2|Bacteria,46V28@74201|Verrucomicrobia,2IVQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02215	349741.Amuc_1818	0.0	871.0	COG1092@1|root,COG1092@2|Bacteria,46UWW@74201|Verrucomicrobia,2ITN4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	RNA cap guanine-N2 methyltransferase	-	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NEGHOLOK_02216	349741.Amuc_1817	2.51e-215	595.0	COG1091@1|root,COG1091@2|Bacteria,46T6F@74201|Verrucomicrobia,2IUPB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	RmlD substrate binding domain	-	-	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NEGHOLOK_02217	349741.Amuc_1816	5.51e-240	658.0	COG4948@1|root,COG4948@2|Bacteria,46X7I@74201|Verrucomicrobia,2IUF3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Mandelate Racemase Muconate Lactonizing	-	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C
NEGHOLOK_02218	349741.Amuc_1815	0.0	1520.0	COG3525@1|root,COG3525@2|Bacteria,46XW1@74201|Verrucomicrobia,2IVFW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Glycosyl hydrolase family 20, domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_02220	349741.Amuc_1813	0.0	882.0	COG0534@1|root,COG0534@2|Bacteria,46VU7@74201|Verrucomicrobia	74201|Verrucomicrobia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NEGHOLOK_02221	349741.Amuc_1812	0.0	1035.0	COG0366@1|root,COG0366@2|Bacteria,46X6K@74201|Verrucomicrobia,2IUQP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	G	Alpha amylase, catalytic domain	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
NEGHOLOK_02222	349741.Amuc_1811	2.54e-83	248.0	COG2731@1|root,COG2731@2|Bacteria	2|Bacteria	G	single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NEGHOLOK_02223	349741.Amuc_1810	7.97e-113	323.0	COG0789@1|root,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
NEGHOLOK_02224	349741.Amuc_1809	4.8e-128	364.0	COG2249@1|root,COG2249@2|Bacteria,46VHD@74201|Verrucomicrobia,2IUV1@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Flavodoxin-like fold	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
NEGHOLOK_02225	349741.Amuc_1806	1.11e-188	523.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,46V66@74201|Verrucomicrobia,2IUU3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Cupin domain	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD,Cupin_2
NEGHOLOK_02226	349741.Amuc_1805	8.08e-100	290.0	COG1359@1|root,COG1359@2|Bacteria,46X0M@74201|Verrucomicrobia,2IWEE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
NEGHOLOK_02227	349741.Amuc_1804	1.66e-127	362.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NEGHOLOK_02228	349741.Amuc_1803	3.6e-265	727.0	COG1408@1|root,COG1408@2|Bacteria,46YVR@74201|Verrucomicrobia,2IUUC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NEGHOLOK_02229	349741.Amuc_1802	1.48e-270	740.0	COG0667@1|root,COG0667@2|Bacteria,46SPV@74201|Verrucomicrobia,2ITQC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NEGHOLOK_02230	349741.Amuc_1801	1.41e-266	729.0	COG1073@1|root,COG1073@2|Bacteria,46WVC@74201|Verrucomicrobia,2IVBE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Peptidase_S15
NEGHOLOK_02231	349741.Amuc_1800	1.3e-205	568.0	COG0656@1|root,COG0656@2|Bacteria,46V1C@74201|Verrucomicrobia,2IUK9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NEGHOLOK_02232	349741.Amuc_1799	9.88e-239	656.0	COG2768@1|root,COG2768@2|Bacteria	2|Bacteria	-	-	-	-	1.2.7.3	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	DUF362
NEGHOLOK_02233	349741.Amuc_1798	6.91e-302	822.0	COG1168@1|root,COG1168@2|Bacteria,46TPH@74201|Verrucomicrobia,2ITQB@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Aminotransferase class I and II	-	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NEGHOLOK_02234	349741.Amuc_1797	2.29e-141	406.0	COG5434@1|root,COG5434@2|Bacteria	2|Bacteria	M	polygalacturonase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF3737
NEGHOLOK_02236	349741.Amuc_1794	2.07e-195	541.0	COG1974@1|root,COG1974@2|Bacteria,46XX7@74201|Verrucomicrobia,2IVZZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	KT	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NEGHOLOK_02237	349741.Amuc_1793	6.03e-292	796.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NEGHOLOK_02240	349741.Amuc_1791	3.4e-178	496.0	COG0265@1|root,COG0265@2|Bacteria,46XAI@74201|Verrucomicrobia,2IUH0@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Trypsin	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
NEGHOLOK_02241	349741.Amuc_1790	5.49e-238	655.0	COG0265@1|root,COG0265@2|Bacteria,46ZI3@74201|Verrucomicrobia,2IUFD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2
NEGHOLOK_02242	349741.Amuc_1789	6.2e-203	561.0	2EV5U@1|root,33NKM@2|Bacteria,46WDA@74201|Verrucomicrobia,2IUTJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02243	349741.Amuc_1788	0.0	1033.0	COG1262@1|root,COG1262@2|Bacteria,46TPR@74201|Verrucomicrobia,2IUDD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase
NEGHOLOK_02244	349741.Amuc_1787	1.85e-282	773.0	COG0457@1|root,COG0457@2|Bacteria,46TAX@74201|Verrucomicrobia,2IUS8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02247	1123070.KB899250_gene528	2.63e-10	65.1	2FHDV@1|root,34981@2|Bacteria,46W9B@74201|Verrucomicrobia,2IURW@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02249	349741.Amuc_1783	8.23e-62	189.0	COG0721@1|root,COG0721@2|Bacteria,46WBS@74201|Verrucomicrobia,2IURF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NEGHOLOK_02250	349741.Amuc_1782	0.0	904.0	COG0154@1|root,COG0154@2|Bacteria,46SCM@74201|Verrucomicrobia,2ITUD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NEGHOLOK_02251	349741.Amuc_1781	2.48e-228	629.0	COG0714@1|root,COG0714@2|Bacteria,46S9V@74201|Verrucomicrobia,2ITT6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ATPase family associated with various cellular activities (AAA)	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NEGHOLOK_02252	349741.Amuc_1780	4.38e-211	583.0	COG1721@1|root,COG1721@2|Bacteria,46TNC@74201|Verrucomicrobia,2IU3V@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NEGHOLOK_02253	349741.Amuc_1779	8.06e-134	380.0	2AX6C@1|root,31P4Y@2|Bacteria,46XSW@74201|Verrucomicrobia,2IWHP@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02254	349741.Amuc_1778	1.33e-228	630.0	COG2304@1|root,COG2304@2|Bacteria,46TTR@74201|Verrucomicrobia,2IU8I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Protein of unknown function (DUF1194)	-	-	-	-	-	-	-	-	-	-	-	-	VWA
NEGHOLOK_02260	349741.Amuc_1497	3.45e-153	439.0	2BDDY@1|root,32730@2|Bacteria,46WKY@74201|Verrucomicrobia,2IWBU@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02262	349741.Amuc_1819	1.31e-38	164.0	28I8X@1|root,2Z8BQ@2|Bacteria,46V28@74201|Verrucomicrobia,2IVQE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02268	323850.Shew_2180	1.78e-34	127.0	2BVU9@1|root,32G90@2|Bacteria,1RJ7Q@1224|Proteobacteria,1SPC7@1236|Gammaproteobacteria	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02270	314271.RB2654_10169	7.53e-96	290.0	COG3677@1|root,COG3677@2|Bacteria,1MXYX@1224|Proteobacteria,2TQR3@28211|Alphaproteobacteria	28211|Alphaproteobacteria	L	Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS1595,Zn_Tnp_IS1595
NEGHOLOK_02271	349741.Amuc_1711	7.2e-174	486.0	2CWYZ@1|root,32T0P@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02272	349741.Amuc_1712	3.89e-209	578.0	COG0074@1|root,COG0074@2|Bacteria,46TRM@74201|Verrucomicrobia,2ITVZ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	-	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
NEGHOLOK_02273	349741.Amuc_1713	2.18e-269	739.0	COG0045@1|root,COG0045@2|Bacteria,46TDG@74201|Verrucomicrobia,2ITNQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
NEGHOLOK_02274	349741.Amuc_1714	3.12e-291	797.0	COG0141@1|root,COG0141@2|Bacteria,46SHG@74201|Verrucomicrobia,2ITG9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
NEGHOLOK_02275	349741.Amuc_1715	5.49e-206	570.0	COG0385@1|root,COG0385@2|Bacteria,46U9V@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bile acid	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	-
NEGHOLOK_02278	349741.Amuc_1718	6.39e-71	213.0	2BK4J@1|root,32EI6@2|Bacteria,46X8G@74201|Verrucomicrobia,2IV09@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02279	349741.Amuc_1719	0.0	874.0	COG1570@1|root,COG1570@2|Bacteria,46SCN@74201|Verrucomicrobia,2ITK4@203494|Verrucomicrobiae	203494|Verrucomicrobiae	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NEGHOLOK_02280	349741.Amuc_1720	0.0	1435.0	COG0318@1|root,COG0318@2|Bacteria,46SG3@74201|Verrucomicrobia,2ITYM@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	AMP-binding enzyme	-	-	2.3.1.40,6.2.1.20	ko:K05939	ko00071,ko00564,map00071,map00564	-	R01406,R04864	RC00014,RC00039,RC00041	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
NEGHOLOK_02281	349741.Amuc_1018	1.39e-128	367.0	COG2095@1|root,COG2095@2|Bacteria,46T9S@74201|Verrucomicrobia,2IUN7@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	MarC family integral membrane protein	-	-	-	ko:K05595	-	-	-	-	ko00000,ko02000	2.A.95.1	-	-	MarC
NEGHOLOK_02282	349741.Amuc_1017	5.94e-178	494.0	COG2267@1|root,COG2267@2|Bacteria,46WQX@74201|Verrucomicrobia,2IUN2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	I	Alpha/beta hydrolase family	-	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
NEGHOLOK_02283	349741.Amuc_1016	1.46e-75	225.0	COG3530@1|root,COG3530@2|Bacteria,46WAN@74201|Verrucomicrobia,2IUTR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative quorum-sensing-regulated virulence factor	-	-	-	ko:K09954	-	-	-	-	ko00000	-	-	-	QSregVF_b
NEGHOLOK_02285	349741.Amuc_1014	1.2e-49	157.0	2EKK3@1|root,33E9Z@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02286	349741.Amuc_1013	2.33e-132	376.0	2DM4H@1|root,31PH4@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2589)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2589
NEGHOLOK_02287	349741.Amuc_1012	1.61e-183	511.0	2BZAR@1|root,32V3N@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02288	349741.Amuc_1011	7.43e-174	488.0	2CIFR@1|root,2Z835@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2589)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2589
NEGHOLOK_02290	349741.Amuc_1010	1.88e-111	320.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	ko:K07705	ko02020,map02020	M00492	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	LytTR,Response_reg
NEGHOLOK_02291	349741.Amuc_1009	7.13e-301	826.0	COG0348@1|root,COG0348@2|Bacteria	2|Bacteria	C	4 iron, 4 sulfur cluster binding	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
NEGHOLOK_02292	349741.Amuc_1008	0.0	2563.0	COG1501@1|root,COG1501@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,F5_F8_type_C,FIVAR,Gal_mutarotas_2,Glyco_hydro_31,NPCBM,NPCBM_assoc
NEGHOLOK_02293	349741.Amuc_1007	7.36e-220	605.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NEGHOLOK_02294	762968.HMPREF9441_03722	5.74e-176	498.0	COG0667@1|root,COG0667@2|Bacteria,4NEB0@976|Bacteroidetes,2FMYE@200643|Bacteroidia	976|Bacteroidetes	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NEGHOLOK_02295	1122931.AUAE01000022_gene1461	2.06e-186	526.0	COG1075@1|root,COG1075@2|Bacteria,4NFSV@976|Bacteroidetes,2FNWB@200643|Bacteroidia,22XH0@171551|Porphyromonadaceae	976|Bacteroidetes	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
NEGHOLOK_02296	349741.Amuc_1003	5.85e-275	751.0	COG1073@1|root,COG1073@2|Bacteria,46XB4@74201|Verrucomicrobia,2IV8U@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	-
NEGHOLOK_02297	349741.Amuc_1002	1.67e-309	843.0	COG0599@1|root,COG0716@1|root,COG0599@2|Bacteria,COG0716@2|Bacteria,46WS0@74201|Verrucomicrobia,2IVQ2@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
NEGHOLOK_02298	693979.Bache_3207	1.03e-159	452.0	COG1028@1|root,COG1028@2|Bacteria,4NFZ8@976|Bacteroidetes,2FPP4@200643|Bacteroidia,4APN2@815|Bacteroidaceae	976|Bacteroidetes	IQ	Short chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NEGHOLOK_02299	742767.HMPREF9456_01686	9.61e-28	113.0	COG1253@1|root,COG1253@2|Bacteria,4NE9R@976|Bacteroidetes,2FN9R@200643|Bacteroidia,22W70@171551|Porphyromonadaceae	976|Bacteroidetes	P	Transporter associated domain	corC_1	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NEGHOLOK_02301	349741.Amuc_0999	4.21e-137	388.0	COG1544@1|root,COG1544@2|Bacteria,46VGU@74201|Verrucomicrobia,2IU7I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NEGHOLOK_02303	1565314.OA34_11780	2.17e-08	60.1	COG4238@1|root,COG4238@2|Bacteria,1N4E5@1224|Proteobacteria,42USX@68525|delta/epsilon subdivisions,2YQ09@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	M	major outer membrane lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02304	349741.Amuc_0996	0.0	1035.0	COG0488@1|root,COG0488@2|Bacteria,46UUC@74201|Verrucomicrobia,2IWNF@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
NEGHOLOK_02306	349741.Amuc_0994	2.57e-170	476.0	COG1028@1|root,COG1028@2|Bacteria,46SNA@74201|Verrucomicrobia,2ITSE@203494|Verrucomicrobiae	203494|Verrucomicrobiae	IQ	KR domain	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NEGHOLOK_02307	349741.Amuc_0993	3.88e-308	837.0	COG1262@1|root,COG1262@2|Bacteria,46UX3@74201|Verrucomicrobia,2ITQQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Sulfatase-modifying factor enzyme 1	-	-	-	-	-	-	-	-	-	-	-	-	FGE-sulfatase,PSCyt1
NEGHOLOK_02309	349741.Amuc_0952	1.15e-05	53.5	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	349741.Amuc_0952|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02311	349741.Amuc_0989	7.45e-49	155.0	COG3339@1|root,COG3339@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF1232)	XK27_09985	-	-	-	-	-	-	-	-	-	-	-	DUF1232
NEGHOLOK_02312	349741.Amuc_0988	1.43e-194	539.0	COG1099@1|root,COG1099@2|Bacteria,46TUW@74201|Verrucomicrobia,2ITR8@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	TatD related DNase	-	-	-	ko:K07051	-	-	-	-	ko00000	-	-	-	TatD_DNase
NEGHOLOK_02313	349741.Amuc_0987	8.94e-56	174.0	2E5PI@1|root,330E7@2|Bacteria,46W49@74201|Verrucomicrobia,2IUXC@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02314	349741.Amuc_0986	4.83e-163	456.0	2CAZH@1|root,2Z7RU@2|Bacteria,46SY1@74201|Verrucomicrobia,2IUAR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
NEGHOLOK_02315	349741.Amuc_0985	0.0	1317.0	COG1053@1|root,COG1053@2|Bacteria,46S7D@74201|Verrucomicrobia,2ITUA@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Fumarate reductase flavoprotein C-term	-	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NEGHOLOK_02316	349741.Amuc_0984	1.29e-187	520.0	COG0479@1|root,COG0479@2|Bacteria,46S82@74201|Verrucomicrobia,2ITQJ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_8
NEGHOLOK_02324	371731.Rsw2DRAFT_2568	1.37e-40	149.0	2D62R@1|root,32TKD@2|Bacteria,1MZY7@1224|Proteobacteria,2UCFJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
NEGHOLOK_02327	349741.Amuc_0386	6.72e-102	325.0	COG4626@1|root,COG4626@2|Bacteria,46ZJ1@74201|Verrucomicrobia,2IV51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02329	349741.Amuc_2060	1.02e-76	258.0	28HPK@1|root,2Z7XJ@2|Bacteria,46VI6@74201|Verrucomicrobia,2IVHI@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
NEGHOLOK_02333	665942.HMPREF1022_02682	9.53e-31	138.0	COG0741@1|root,COG0741@2|Bacteria,1PFUK@1224|Proteobacteria,433SF@68525|delta/epsilon subdivisions,2WYC3@28221|Deltaproteobacteria	28221|Deltaproteobacteria	M	lytic transglycosylase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02335	270374.MELB17_24182	5.36e-09	71.2	2DBPZ@1|root,2ZABJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02342	349741.Amuc_1037	6.21e-39	129.0	29038@1|root,2ZMTB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02343	349741.Amuc_1036	0.0	1159.0	COG0481@1|root,COG0481@2|Bacteria,46SA7@74201|Verrucomicrobia,2IU2I@203494|Verrucomicrobiae	203494|Verrucomicrobiae	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
NEGHOLOK_02345	349741.Amuc_1034	9.83e-235	645.0	COG0526@1|root,COG0526@2|Bacteria,46X62@74201|Verrucomicrobia,2IUKR@203494|Verrucomicrobiae	203494|Verrucomicrobiae	CO	Thioredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_2,Thioredoxin_7
NEGHOLOK_02346	349741.Amuc_1033	0.0	1235.0	COG3119@1|root,COG3119@2|Bacteria,46U1Z@74201|Verrucomicrobia,2ITR9@203494|Verrucomicrobiae	203494|Verrucomicrobiae	P	Domain of unknown function (DUF4976)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NEGHOLOK_02347	349741.Amuc_1032	0.0	1082.0	COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae	2|Bacteria	G	Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_02348	349741.Amuc_1031	0.0	979.0	COG0215@1|root,COG0215@2|Bacteria,46SES@74201|Verrucomicrobia,2ITI3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	J	tRNA synthetases class I (C) catalytic domain	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
NEGHOLOK_02349	349741.Amuc_1030	2.27e-75	225.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NEGHOLOK_02350	349741.Amuc_1029	5.74e-211	583.0	COG0697@1|root,COG0697@2|Bacteria	2|Bacteria	EG	spore germination	ybfH	-	-	-	-	-	-	-	-	-	-	-	EamA
NEGHOLOK_02351	349741.Amuc_1028	9.28e-139	394.0	2A0TH@1|root,30NY5@2|Bacteria,46XSP@74201|Verrucomicrobia,2IWHD@203494|Verrucomicrobiae	203494|Verrucomicrobiae	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02352	349741.Amuc_1027	0.0	1266.0	COG0488@1|root,COG0488@2|Bacteria,46V06@74201|Verrucomicrobia,2IU2D@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	ABC transporter	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NEGHOLOK_02353	349741.Amuc_1026	3.62e-121	345.0	COG0652@1|root,COG0652@2|Bacteria,46V73@74201|Verrucomicrobia,2IU91@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NEGHOLOK_02354	349741.Amuc_1025	7.48e-188	521.0	COG1281@1|root,COG1281@2|Bacteria,46UDA@74201|Verrucomicrobia,2IU4G@203494|Verrucomicrobiae	203494|Verrucomicrobiae	O	Hsp33 protein	-	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NEGHOLOK_02357	349741.Amuc_1022	3.56e-234	644.0	COG2755@1|root,COG2755@2|Bacteria,46VAZ@74201|Verrucomicrobia,2IUIU@203494|Verrucomicrobiae	2|Bacteria	E	PFAM lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NEGHOLOK_02360	349741.Amuc_2144	0.0	1087.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,46UJW@74201|Verrucomicrobia,2IU09@203494|Verrucomicrobiae	203494|Verrucomicrobiae	C	Catalyzes the reversible hydration of fumarate to (S)- malate	-	-	4.2.1.2	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
NEGHOLOK_02362	349741.Amuc_2146	2.53e-106	306.0	COG0720@1|root,COG0720@2|Bacteria,46VC9@74201|Verrucomicrobia,2IVQQ@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	6-pyruvoyl tetrahydropterin synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
NEGHOLOK_02364	349741.Amuc_2148	0.0	1095.0	COG3525@1|root,COG3525@2|Bacteria,46UY2@74201|Verrucomicrobia,2IU6A@203494|Verrucomicrobiae	2|Bacteria	G	Glycoside hydrolase, family 20, catalytic core	-	-	3.2.1.52	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	M00079,M00628	R00022,R05963,R06004,R07809,R07810,R10831,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	F5_F8_type_C,Glyco_hydro_20,Glyco_hydro_20b
NEGHOLOK_02365	349741.Amuc_2149	1.85e-300	825.0	COG0541@1|root,COG0541@2|Bacteria,46SIU@74201|Verrucomicrobia,2ITP6@203494|Verrucomicrobiae	203494|Verrucomicrobiae	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NEGHOLOK_02366	349741.Amuc_2150	3.4e-227	625.0	COG0379@1|root,COG0379@2|Bacteria,46SA1@74201|Verrucomicrobia,2ITV3@203494|Verrucomicrobiae	203494|Verrucomicrobiae	H	Quinolinate synthetase A protein	-	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
NEGHOLOK_02367	349741.Amuc_2151	8.31e-254	695.0	COG1565@1|root,COG1565@2|Bacteria,46YUZ@74201|Verrucomicrobia,2IU7W@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Putative S-adenosyl-L-methionine-dependent methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
NEGHOLOK_02373	278957.ABEA03000173_gene2424	5.05e-34	144.0	28HPK@1|root,2Z7XJ@2|Bacteria,46VI6@74201|Verrucomicrobia	74201|Verrucomicrobia	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
NEGHOLOK_02374	349741.Amuc_0386	2.46e-133	406.0	COG4626@1|root,COG4626@2|Bacteria,46ZJ1@74201|Verrucomicrobia,2IV51@203494|Verrucomicrobiae	203494|Verrucomicrobiae	S	Terminase	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02380	411461.DORFOR_03187	3.94e-200	560.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes,25E2S@186801|Clostridia,27V7W@189330|Dorea	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
NEGHOLOK_02382	397290.C810_03660	2.66e-59	197.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NEGHOLOK_02383	1235797.C816_03597	0.0	988.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,2N6IE@216572|Oscillospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NEGHOLOK_02384	1235797.C816_03598	5.54e-30	106.0	2CV1B@1|root,32SWM@2|Bacteria,1VBZB@1239|Firmicutes,24T2H@186801|Clostridia,2N8WT@216572|Oscillospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02385	1235797.C816_02666	6.44e-72	216.0	COG1349@1|root,COG1349@2|Bacteria,1VSSV@1239|Firmicutes,24YNM@186801|Clostridia	2|Bacteria	GK	Replication initiator protein A (RepA) N-terminus	rpiA	-	5.3.1.6	ko:K01807,ko:K02444	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000,ko03000	-	-	-	DeoRC,HTH_DeoR,RepA_N,Rib_5-P_isom_A
NEGHOLOK_02386	1410626.JHXB01000006_gene1903	1.33e-14	73.2	2C3X6@1|root,33FVG@2|Bacteria,1VNV7@1239|Firmicutes,24VKF@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02387	97139.C824_01292	0.0	915.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,36F4Z@31979|Clostridiaceae	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NEGHOLOK_02388	1235798.C817_03503	3.34e-232	649.0	COG3290@1|root,COG3290@2|Bacteria,1V0KZ@1239|Firmicutes,25BG0@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NEGHOLOK_02389	1235798.C817_03504	6.02e-171	478.0	COG3279@1|root,COG3279@2|Bacteria,1V8B0@1239|Firmicutes,24M07@186801|Clostridia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NEGHOLOK_02390	1235798.C817_03505	1.71e-75	229.0	2F9YM@1|root,3427W@2|Bacteria,1VXJ4@1239|Firmicutes,251PJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02396	742738.HMPREF9460_03024	1.73e-50	162.0	2DX19@1|root,342XR@2|Bacteria,1VXCZ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrbC
NEGHOLOK_02397	1378168.N510_03447	5.61e-123	367.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes	1239|Firmicutes	U	COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
NEGHOLOK_02398	97139.C824_06110	0.0	1211.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,36F7Z@31979|Clostridiaceae	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	Intron_maturas2,RVT_1
NEGHOLOK_02399	1235797.C816_01624	4.15e-17	80.1	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,2N6ZV@216572|Oscillospiraceae	186801|Clostridia	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
NEGHOLOK_02400	1235835.C814_01981	3.12e-217	599.0	28JXD@1|root,2Z9MW@2|Bacteria,1UZPJ@1239|Firmicutes,247ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02401	1235835.C814_01982	3.82e-168	472.0	28N5R@1|root,2ZBAW@2|Bacteria,1UZ09@1239|Firmicutes,24DUD@186801|Clostridia,3WNGA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02402	397288.C806_04788	2.07e-60	186.0	2AKFX@1|root,31B7N@2|Bacteria,1V7VY@1239|Firmicutes,24M21@186801|Clostridia,27S6R@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02403	1235798.C817_03727	2.01e-243	667.0	COG0358@1|root,COG0358@2|Bacteria,1TSIU@1239|Firmicutes,2495Y@186801|Clostridia,27VYX@189330|Dorea	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
NEGHOLOK_02404	1235798.C817_03726	8.31e-82	248.0	COG3935@1|root,COG3935@2|Bacteria,1TPPF@1239|Firmicutes,249NG@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_36,RepA_N
NEGHOLOK_02407	457398.HMPREF0326_02515	3.11e-69	224.0	2C57M@1|root,2ZD3J@2|Bacteria,1RCQE@1224|Proteobacteria,42YSN@68525|delta/epsilon subdivisions,2WUF3@28221|Deltaproteobacteria,2M94J@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02413	665942.HMPREF1022_01003	8.57e-153	465.0	28I8X@1|root,2Z8BQ@2|Bacteria,1MW9X@1224|Proteobacteria,42Z58@68525|delta/epsilon subdivisions,2WTW4@28221|Deltaproteobacteria,2M8HG@213115|Desulfovibrionales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02417	97139.C824_04686	5.37e-50	160.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,36K3I@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NEGHOLOK_02421	397290.C810_01580	1.6e-40	134.0	2CV1B@1|root,32SWM@2|Bacteria,1VBZB@1239|Firmicutes,24T2H@186801|Clostridia,27SNX@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02422	397290.C810_01581	7.84e-128	369.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,247S8@186801|Clostridia,27KUP@186928|unclassified Lachnospiraceae	186801|Clostridia	D	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NEGHOLOK_02423	1235800.C819_00849	1.97e-70	214.0	COG4227@1|root,COG4227@2|Bacteria,1TRWD@1239|Firmicutes,248KN@186801|Clostridia,27P49@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Protein of unknown function (DUF3849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3846,DUF3849,YodL
NEGHOLOK_02424	1235800.C819_00850	4.35e-144	406.0	COG2088@1|root,COG2088@2|Bacteria,1VXZ5@1239|Firmicutes,251SX@186801|Clostridia,27PTI@186928|unclassified Lachnospiraceae	186801|Clostridia	M	SpoVG	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
NEGHOLOK_02425	1235800.C819_00851	2.15e-203	563.0	28HUM@1|root,2Z81B@2|Bacteria,1TNZ2@1239|Firmicutes,248SU@186801|Clostridia,27JJK@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02427	1235835.C814_02204	3.05e-200	555.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3WG7N@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NEGHOLOK_02428	1235835.C814_02205	1.39e-32	113.0	2DNP9@1|root,32YE1@2|Bacteria,1VEMU@1239|Firmicutes,25B9B@186801|Clostridia,3WS50@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
NEGHOLOK_02429	97139.C824_04787	6.12e-193	543.0	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,249ZV@186801|Clostridia,36F5R@31979|Clostridiaceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,Mu-transpos_C,rve
NEGHOLOK_02430	1235798.C817_05887	1.84e-167	471.0	COG3267@1|root,COG3267@2|Bacteria,1TRGM@1239|Firmicutes,24EPV@186801|Clostridia,27W97@189330|Dorea	186801|Clostridia	U	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22
NEGHOLOK_02434	1378168.N510_01949	8.28e-162	454.0	COG3279@1|root,COG3279@2|Bacteria,1VFEP@1239|Firmicutes	2|Bacteria	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,LytTR,Response_reg
NEGHOLOK_02435	1378168.N510_01948	2.13e-239	669.0	COG3290@1|root,COG3290@2|Bacteria,1V46S@1239|Firmicutes	1239|Firmicutes	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NEGHOLOK_02436	1226322.HMPREF1545_00792	2.71e-43	154.0	COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,248IJ@186801|Clostridia,2N6TF@216572|Oscillospiraceae	186801|Clostridia	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38,rve
NEGHOLOK_02437	1514668.JOOA01000002_gene2032	7.98e-136	404.0	COG3464@1|root,COG3464@2|Bacteria,1V4W1@1239|Firmicutes,24HR1@186801|Clostridia,3WQSC@541000|Ruminococcaceae	186801|Clostridia	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3
NEGHOLOK_02438	1235792.C808_02594	2.33e-306	841.0	COG3039@1|root,COG3039@2|Bacteria,1TQF8@1239|Firmicutes,24AUQ@186801|Clostridia,27R0Z@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6
NEGHOLOK_02439	1235797.C816_04041	0.0	954.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,2N693@216572|Oscillospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NEGHOLOK_02441	397288.C806_05053	3.81e-149	423.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,27J6D@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NEGHOLOK_02442	397290.C810_04617	6.39e-89	260.0	28NID@1|root,2ZBJU@2|Bacteria,1V1MS@1239|Firmicutes,25I4E@186801|Clostridia,27RRI@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cysteine-rich VLP	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_VLP
NEGHOLOK_02443	397290.C810_04546	4.72e-67	218.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,27IJ8@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NEGHOLOK_02444	411902.CLOBOL_03890	9.14e-84	256.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,24DPG@186801|Clostridia	186801|Clostridia	D	AAA domain	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NEGHOLOK_02445	411902.CLOBOL_03889	1.55e-126	370.0	COG1475@1|root,COG1475@2|Bacteria,1V8BD@1239|Firmicutes,2494F@186801|Clostridia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NEGHOLOK_02447	1469948.JPNB01000002_gene3079	6.66e-05	43.1	2BEYZ@1|root,328QN@2|Bacteria,1UUNU@1239|Firmicutes,2579Y@186801|Clostridia,36TX1@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02449	97139.C824_00725	7.67e-100	300.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,24DPG@186801|Clostridia,36F8Z@31979|Clostridiaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NEGHOLOK_02450	1235797.C816_01694	1.29e-278	762.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
NEGHOLOK_02451	1235797.C816_01693	2.72e-42	138.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NEGHOLOK_02452	1235800.C819_00852	8.89e-299	820.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27JVV@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NEGHOLOK_02455	1235799.C818_00209	1.52e-64	197.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24KNI@186801|Clostridia,27TU3@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
NEGHOLOK_02456	411902.CLOBOL_05543	9.21e-38	132.0	2BXGH@1|root,32R1A@2|Bacteria,1V8FX@1239|Firmicutes,24JT8@186801|Clostridia	186801|Clostridia	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
NEGHOLOK_02457	411902.CLOBOL_05544	1.2e-77	244.0	2CKKE@1|root,2ZC1Q@2|Bacteria,1V2EX@1239|Firmicutes,25MZG@186801|Clostridia,2238G@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02458	1235797.C816_02098	4.84e-175	501.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,2N70N@216572|Oscillospiraceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NEGHOLOK_02459	693746.OBV_34800	1.24e-11	60.8	COG3311@1|root,COG3311@2|Bacteria,1VKNA@1239|Firmicutes	1239|Firmicutes	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
NEGHOLOK_02461	397290.C810_04616	2.49e-182	507.0	COG1349@1|root,COG1349@2|Bacteria,1TSUV@1239|Firmicutes,24CQC@186801|Clostridia,27J6D@186928|unclassified Lachnospiraceae	186801|Clostridia	GK	Replication initiator protein A (RepA) N-terminus	repA	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NEGHOLOK_02464	1121115.AXVN01000013_gene3169	9.12e-70	230.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3XZH0@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
NEGHOLOK_02468	882.DVU_1721	1.45e-35	136.0	28HPK@1|root,2Z7XJ@2|Bacteria,1NBHR@1224|Proteobacteria,43E94@68525|delta/epsilon subdivisions,2X01M@28221|Deltaproteobacteria,2M9TF@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Bacteriophage head to tail connecting protein	-	-	-	-	-	-	-	-	-	-	-	-	Head-tail_con
NEGHOLOK_02471	1235800.C819_03974	1.35e-162	457.0	2948F@1|root,2ZRNR@2|Bacteria,1V25Y@1239|Firmicutes,24BP0@186801|Clostridia,27IQ3@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NEGHOLOK_02472	1235790.C805_01779	2.38e-35	120.0	COG2105@1|root,COG2105@2|Bacteria,1VGQA@1239|Firmicutes,24S5K@186801|Clostridia,25XJG@186806|Eubacteriaceae	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
## 1875 queries scanned
## Total time (seconds): 248.63933539390564
## Rate: 7.54 q/s