LOCUS       c00258_gnlPro..        12968 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NNKCLJJH_258.
ACCESSION   c00258_gnlPro..
VERSION     c00258_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:10:32
            Original ID  :: gnl|Prokka|NNKCLJJH_258
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12968
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12968
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5337:10674]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5338..10674
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12968
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12968
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(3..803)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyridoxal_deC"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg258_1"
                     /sec_met_domain="Pyridoxal_deC (E-value: 8.9e-42, bitscore:
                     132.8, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDCNCDLRDGDAKTAVFGSNEMLQPAPVDTIPMEPTTPQIAYQM
                     VKDETFAQTQPRLNLATFVTTYMDDYATKLMNEAININYIDETEYPRIAVMNAKCINIM
                     ANLWNSPEQAKWKSGALAIGSSEACMLGGVAAWLRWRDRRKAQGKPTDKPNFVISSGFQ
                     VVWEKFAQLWQIEMRQVPLTLDKPTLDPEEALKMCDENTICIVPIQGVTWTGLNDDVEA
                     LDKALDAYNAKTGYDIPIHVDAATGGFILPFLSPETKWDFRLKWV"
     CDS             1191..2381
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 56.3; E-value: 8.7e-18)"
                     /gene_kind="transport"
                     /locus_tag="ctg258_2"
                     /sec_met_domain="MFS_1 (E-value: 1.8e-18, bitscore: 56.3,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVQTGQGTIPLITLIGIFSISALNALPGLAVSPILGDLNKIFPS
                     ATDLEIQMLSSLPSLLIIPFILLSGKLTEKVNNLLLLQIGLAIFGVSGILYLLSNKMWQ
                     LIAISAMLGIGSGLIVPLSTGLISRYFVGAYRTKQFGYSSAITNITLVLATTLTGYLAE
                     VNWHLPFLVYLFPFISIFLTHYLKKDLSSYHPSDDIPSDTAKEMGKRGMNVKALIKLMA
                     FYGLATYLVIIISFNLPFLMEEYGLSSGRAGILISLFFLAIMAPGFVLNRIVQVLGRRI
                     YMVCLLMIACGMGIILLSRSEILIALGCVLNGLSYGIIQPLIYDKTSDVAVPHKVTLAL
                     AFVMAMNYVAILLCPFIVDAVQSLFHSDSQTFAFWLNLMVALMAMFVVMKQEKLSL"
     CDS             2413..3333
                     /locus_tag="ctg258_3"
                     /transl_table=11
                     /translation="MNKQVEANLSMVVSKALGGFNMNALKYLLPLWIAPVTGVTFRLVF
                     GAAAFWLIDIFCKPENSTIRQKWQLFMLGALGIYGYMFFYLLGISKTTPVSSSIFVSLE
                     PIWVFIIAVLFYKEKVTWMKVFGIGMGLGGAILCISTQPSDDLASNAPLGNLMCLVSSL
                     VYAVYLVLSNRLLKGVGNMTMLKYTFLGAAVMAVIVNTIYGFDAPILRMSLFSTPMLVL
                     LFVLVFPTTISYLLLPLGLKYLKTTLVAIYGYLILIVATVTSFILGQDRFSWTQLAAIV
                     LICASVYLVEVAESKSEKQIISKSR"
     CDS             3514..4710
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg258_4"
                     /sec_met_domain="PALP (E-value: 1.4e-87, bitscore: 283.6,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLQLDAIYKAAHVLKEVVRRTDLIYAPQINPESTVYLKPENLQFT
                     GSFKVRGAYYKISQLSDEEKARGVIACSAGNHAQGVALAATKCGIKSLICLPEGAPISK
                     VEATKHYGAEVCLVPGVYDDAYQKALQLRDEKGYTFVHPFDDENVIAGQGTIGLELLEE
                     MPDVEVVIVPIGGGGLISGVAYALKALKPSVKVYGVQALGAASMANSILHSRIERLHSV
                     STFADGIAVKEPGTNTFDLVNQYVDGIVTVTEDEIAAAILALIERQRIVAEGAGAVSVA
                     AAMFNKVPVKGKKTVCLVSGGNIDVTILSRVISRGMAKSGRTYAVTLDLIDKPGQLLGV
                     SKIIAEQGGNVISVHHERNSESADVTGCALRVVMETRNEEHIASIRQKLLDAGYVIMK"
     CDS             4856..5317
                     /locus_tag="ctg258_5"
                     /transl_table=11
                     /translation="LPQFCNVEFAKMTDIIKHRGIVENIEGSHVRVRIVQTSACSACSV
                     KGHCNASESKEKLIDVFDMKASSYRIGEEVMIYGTTSMGMQAVLLAFGIPFLVLLITLF
                     ISMRFTGGDELRSALVALSALLPYYLIIYVCRNKLSKKFSFTLEPIKNN"
     CDS             5338..6285
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 40.3; E-value:
                     1.2e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_6"
                     /sec_met_domain="Fer4_7 (E-value: 2.6e-13, bitscore: 40.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 2.2e-10, bitscore: 30.0,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.2e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.4e-09, bitscore: 26.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 4.3e-08, bitscore: 23.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.2e-10, bitscore: 30.8,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLILVAVISLGAIGLIAAVILYAASKKFAVYEDPRIAKVSEVLP
                     QANCGGCGYPGCSGFAGACVKAADAGSLEGKLCPVGGAPVMEKVAAILGLEAVAAEPKV
                     AVVRCNGSCENRPRTALYDGAKSCAIAHATSGGETGCTFGCLGCGDCVEVCQFDAIHMN
                     PETGLPEVDEEKCTACGACSKACPRKIIEIRPKGKNNRRVVVMCVNKDKGAVANKACKA
                     SCIGCGKCVKVCPFEAITLENNLAYIDPAKCKSCRKCESECPKGAIQAINFPPRKPKVE
                     VPAGEAAAKPAAKVEASKVETPEAVKAEAPKAEA"
     CDS             6325..7662
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_7"
                     /sec_met_domain="Fer4_7 (E-value: 1.4e-09, bitscore: 28.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.3e-17, bitscore: 52.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.4e-53, bitscore:
                     170.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 1.1e-31, bitscore: 98.7,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKTFRIGGVHPAENKLSAGKAIETLALPKQAVFPLSQHIGAPATA
                     IVKKGDVVKVGTKIAEAGGFVSAAIFSSVSGKVNKVDAVIDASGYRKPAIFIDVDGDEW
                     EESIDRSSTLVKECALTPEEIVAKVKNAGVVGMGGACFPTHVKLSPPPGCKAECVIINA
                     VECEPYLTADHRLMLEKADEVLVGVSILMKAAKVTKGYIGIENNKPDAIKLMTEKAAQY
                     PGIEVVPLQVKYPQGGEKQLIDAVIGRQVPAPPAIPINVGAVVQNVGTAFAVYEAVQKN
                     KPLFERIVTVTGKSVRNPSNFLTRMGTPMSQLIDAAGGLPEDTGKVIGGGPMMGKALVN
                     TEVPICKGSSGVLIMNDKEAARAEAQPCIRCAKCVNVCPMGLEPFLLATLSAHKDWERV
                     EKEDVMSCIECGSCQFTCPSHRYLLDYIRLGKGTVGGIIRARNAKK"
     CDS             7677..8666
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_8"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.5e-120,
                     bitscore: 391.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKLIVSLSPHVHSGDSIQKNMYGVLIALIPALLVSFYMFGLGA
                     VVVTLTSVAACVFFEWAITKFILKRERSTICDGSAIITGVLLAFNLPSNLPLWIIIIGA
                     LVAIGVGKMTFGGLGCNPFNPALVGRIFLLISFPVQMTSWPLVQQWGSYTDAETGATPL
                     ALMKMAVKGDVNALGQLPDTLSLFLGNNPGSLGEVSALALLLGLGYMLWKKIISWHIPV
                     SILVTVFVFAGLMHLVDPVAYASPLAHLFTGGLMLGAIFMATDYVTSPMTHKGMIIYGV
                     AIGFLTVVIRLFGAYPEGMSFAIFIMNAFTPLINTYCKPKRFGEVVKK"
     CDS             8663..9454
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_9"
                     /sec_met_domain="FMN_bind (E-value: 2.3e-22, bitscore:
                     69.3, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLESSLKNMVIVLTAITVIATGLLAYVNQLTAGPIAEANAKAL
                     SDAIAVVVPGFDNNPAEAPETIELDGATYKIYKATKGGEFIGAAVESSANGFGGALSVL
                     VGFDKEGNIIDYSLLSHAETPGLGSKAADWFKKGAKGDITGMNPGQGALVVNKDGGQID
                     AITASTITTRAFLKAVNNAYAAYSGQNVDGASGATQQVSETVAENATACDAQCEGNEAC
                     KQVCDSTACKTVCSDKCDPANCDKADCKKVECPKQDCKNKK"
     CDS             9469..10053
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_10"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.8e-71, bitscore:
                     228.5, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNFKVLMNGIVKENPTFVLLLGMCPTLGTTSSAINGMGMGLATA
                     FVLICSNVVISAIKNLIPDMVRIPAFVVVIASFVTLLQMIMQAYVPALYATLGLFIPLI
                     VVNCILLGRAEAFAAKNGPVPSFFDGLGMGLGFTLALTILGGVREFLGTGKLFDITIMP
                     EQYGMLIFVLAPGAFIALGYLIAIVNKLKKA"
     CDS             10072..10674
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg258_11"
                     /sec_met_domain="Rnf-Nqr (E-value: 3.5e-64, bitscore:
                     205.8, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFITAIFVNNIVLSQFLGICPFLGVSKKVETATGMGAAVA
                     FVLTIATIVTYLIQKFVLDAFGLEYLQTIAFILVIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDFDLLTGVVYAFSTALGFALAMVLFAGIREQLSLVNIP
                     KGMQGMAIALVTAGLLAMAFMGFSGVDKGLGVLFGIE"
     CDS             10815..11711
                     /locus_tag="ctg258_12"
                     /transl_table=11
                     /translation="MAMTLIVLAATMGNKYGGLKQLEGIGPNGETILDFSIYDAVRVGF
                     DKIVFVISRHFEQEFKKLVSGKYEHVVEVEYVYQDVETIPEEKRNPKRKALYGSVRAVL
                     MGEELIDSPFGVINAVNFYQRESFELLYDNLVMLGEADYHSFNICYRLRNVLAESGGVT
                     RGICEVDEKGYLLSVTDRVGVERISGNPMYPNELHKWVALDDNSLVSMNMWGFTPQVFG
                     EMKKAFDKFIDENGMDMKAHYSIPAFMNERIADGVRVKVIETPARWMGLVSHDDKIQVL
                     LRINDMIRKGIYPSKLF"
     CDS             11744..12778
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg258_13"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 3.4e-53, bitscore:
                     170.9, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYDVVIVDNLSNSSADVVDN
                     IEKVSGIRPAFEKLDCLDFEGMDKLFTKYPGIKGIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIIFSSSCTVYGQPDVLPVTEEAPIKKAESPYGNTKQINEEII
                     RDTVASGSPINAIMLRYFNPIGAHPTALIGELPNGVPQNLLPYVTQTAMGIREKLSVFG
                     DDYDTPDGSCIRDYIYVVDLAKAHVIAMDRILNNKQKEKVEVFNIGTGKGVSVLELINT
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAEANLEDTLRSAWNWQLKLRE
                     RGIQ"
ORIGIN
        1 agaacccatt tcaaacggaa gtcccatttc gtttcggggc tgaggaacgg caggatgaag
       61 ccaccggttg cggcatctac gtggatagga atatcatagc cggttttggc gttgtaggca
      121 tccagcgctt tgtccaatgc ttccacgtca tcgttcagac ctgtccatgt cacaccttgg
      181 ataggaacaa tacagatggt gttctcgtca cacatcttta aggcttcttc ggggtccagg
      241 gtgggcttgt ccagagtaag aggtacttgg cgcatctcaa tctgccaaag ttgggcgaat
      301 ttctcccata caacctggaa accgcttgaa atgacgaagt taggtttgtc ggtcggtttg
      361 ccctgggctt tacgtctgtc tctccagcgc aaccaggcag ctacaccacc cagcatacaa
      421 gcctcgctgg agccgatggc caacgctcct gatttccatt ttgcctgttc gggggaattc
      481 cataggttgg ccatgatgtt gatacatttg gcattcatca cggcgatacg cgggtactct
      541 gtttcatcaa tatagttgat gttgatagct tcgttcatca atttggtagc ataatcgtcc
      601 atataggtgg taacgaaagt agccagatta agacgaggct gggtttgggc gaatgtttcg
      661 tctttaacca tttgataagc aatctgcgga gtggtaggtt ccatgggaat ggtgtctacc
      721 ggagcaggtt gcagcatttc gtttgaacca aacacggctg ttttggcgtc accgtctctc
      781 aaatcacaat tacaatcttt catttttact taaagtttag gttagtaata caatgaagaa
      841 cgtgggagtt tcccgcgttt ttctccctca acataggggt tggtgaaaag ttccttgatt
      901 ttatgttttt taatgtaagt agggggaata caaaaaaacg atgggaatca ttgtactatg
      961 aacgaaaaag agataccttt gtttatacat aaaatcattg gatgcccgta tccgatattt
     1021 taggggtatg taatttgata aactgcgttt aggaaattaa cataggcgta aactttgaca
     1081 ctacccggca taatattttg gaatggaaag taaaggaata aacgatatgt cgctttgaac
     1141 caaacgtctt ttgccttgtt gtgtatctca tacaataaat tactacaagt atgaaagtac
     1201 agacagggca ggggactatt cccctcatta ctttaatagg tatattttcc atttcggcat
     1261 taaatgcatt gccgggattg gcggtttctc ccattttggg cgatttgaat aaaatctttc
     1321 cgtctgctac agacttggaa atccagatgc tgtcctcgtt gccgtcactt cttattattc
     1381 cttttatctt gttgtcgggt aagctgacag agaaagtgaa caacctcttg ctgctgcaaa
     1441 tcggcctggc catctttggg gtgagtggta tcctttatct gctctccaat aagatgtggc
     1501 aactgatagc catcagcgcc atgttgggga tagggtccgg gttgattgtt ccgctttcca
     1561 ccggattgat atcccgttat tttgtgggag cttaccgtac gaaacagttc ggttacagtt
     1621 ctgccataac caatatcacc ttggtactgg ccaccacatt gactggctat ctggcggaag
     1681 tgaactggca tttgccgttt ttggtttatc tgtttccttt tatatccatt tttcttactc
     1741 attatctgaa gaaagacctc tccagttatc atccgtctga tgatattccg tctgataccg
     1801 ccaaagaaat gggcaagagg ggaatgaatg tcaaggcctt aatcaagctg atggcttttt
     1861 acggtctggc tacttatctg gtaatcatta tcagtttcaa ccttcctttt ctgatggaag
     1921 agtacgggct ttccagtggc agggcaggaa tattgatttc cttgtttttc cttgctatca
     1981 tggcgccggg ctttgtgctg aacaggatag tgcaagtgtt ggggcgtcgt atctatatgg
     2041 tttgtttgtt gatgatagct tgtgggatgg gaattatttt gctcagccgt tctgagatat
     2101 tgattgcttt ggggtgtgtc ctgaacggtc tttcatacgg tatcatccag ccgttgattt
     2161 atgataagac ctctgatgtg gccgtacctc ataaggtgac attggcactt gcctttgtga
     2221 tggctatgaa ttatgtggct atcctgcttt gtccttttat tgtagatgca gtacagagct
     2281 tgtttcattc tgactcgcag acttttgctt tctggctcaa tttgatggtg gcgctgatgg
     2341 ccatgtttgt ggtgatgaag caagaaaagt tgagtttata agaaaaatac ccacgtaata
     2401 acagcatgaa gtatgaataa acaagttgaa gcaaacctta gcatggttgt ctccaaagcg
     2461 ttgggaggct ttaatatgaa cgcgttgaaa tatcttttac ctttgtggat agctcctgtg
     2521 acaggggtta ctttccgatt ggtatttggg gccgccgctt tttggcttat tgatatattt
     2581 tgcaaacccg aaaactccac tattcgtcag aaatggcagc tttttatgtt aggggcttta
     2641 ggtatttacg gatatatgtt tttttatctg ctgggtatca gtaagaccac tccggtttcc
     2701 agttccattt ttgtcagttt ggagcctata tgggtattca ttattgctgt attgttttat
     2761 aaggaaaaag taacttggat gaaagtgttt ggtattggaa tggggttggg aggagctatt
     2821 ctttgcattt ctacacagcc tagtgacgat cttgcctcta atgctccgtt aggtaattta
     2881 atgtgtttgg tcagttcgct ggtttatgcc gtctatcttg ttctcagcaa tcgtctgtta
     2941 aaaggggtgg gaaatatgac gatgttgaaa tatacctttt taggggcggc tgtcatggct
     3001 gttattgtca atacaattta cggctttgat gctcctatac tgagaatgtc acttttctct
     3061 actcctatgt tggtcttgct ttttgttttg gtattcccta ccactattag ttatttacta
     3121 cttcccctcg gattgaaata tctgaaaact acattggtag ctatttatgg atatttaatt
     3181 ttgattgttg ctacggtgac ctcttttatt ttggggcagg atcgcttctc atggacgcag
     3241 ttggcggcga ttgttcttat ttgtgccagt gtttatctgg tagaggtggc cgagagtaaa
     3301 agtgaaaaac agattatatc gaaatccaga taagacaccg ggaaaaaagt ataagaccct
     3361 aagaaaaaaa ttatcgcggt gtgtaatgta aagaaactta ccggcaaatg aatgagcgaa
     3421 aaaaaagaat gcaactttac atcgaaagcg agtgtaagga atcaatttta tttgtagctt
     3481 tgcacccaat taaaaaacaa gagtgttata cctatgctac aattagatgc aatatacaag
     3541 gcggctcatg tcctgaaaga ggttgtccgt cgcactgatt tgatttatgc tcctcagata
     3601 aatcctgaga gtacagttta tctgaagccc gaaaacctgc aattcacagg atcgtttaaa
     3661 gtgcgtggtg cttattacaa gatttcccaa ttgtctgatg aagaaaaggc gagaggtgtg
     3721 atagcctgtt ctgccggtaa tcatgcgcaa ggggtggcat tggctgccac taagtgtggc
     3781 atcaagtcgt tgatttgtct tccagaggga gcacctatat ctaaagttga ggctacgaag
     3841 cattatgggg cggaagtttg tttggttccg ggagtctatg atgatgctta tcagaaagct
     3901 ctgcaattac gtgatgaaaa gggatatact tttgttcatc cctttgatga cgagaatgtg
     3961 atagccggac aaggtactat cggtttggag ttattggagg aaatgccgga tgtggaggta
     4021 gtcattgtcc ccattggtgg gggcggactg atttcgggag tggcttatgc gttgaaggct
     4081 ttgaaaccgt ctgtcaaggt atatggtgta caggcgttgg gtgcggccag tatggcaaat
     4141 tctattcttc attcgcgtat tgagcgtctt cactctgttt ccacttttgc cgatggaatc
     4201 gcggtgaaag agccgggaac aaatactttt gacttggtta atcagtatgt ggacggaatt
     4261 gtaactgtga ccgaggatga gattgccgca gctattctgg cattgataga acgccagcgg
     4321 attgttgcag agggggcggg agctgtgtcc gttgctgcag ccatgttcaa taaggtaccg
     4381 gtaaagggta agaaaactgt ttgcctggtg tctggaggta atattgatgt gacgatattg
     4441 agccgtgtca tcagtcgcgg tatggcaaag tcgggacgta cctatgcagt aactttggac
     4501 ttgatagaca aaccggggca gctgttggga gtcagcaaaa ttatcgcaga gcagggagga
     4561 aatgtaattt ctgtacatca tgagcgaaat agtgagagtg cagatgtcac cggatgtgcc
     4621 cttcgtgtcg ttatggaaac cagaaacgag gaacatatag catccattcg tcaaaaactc
     4681 ttggatgcag gctatgtgat aatgaaataa attatatact ttacaagtag aaagggggga
     4741 atttaaaatt ttcctccctt tcttgtttct aattttaatt tctccacaca aaaaatcgat
     4801 ttttatagtg aaaatatcat tttatacttc ttagaatcca attaaaatcg tacatttgcc
     4861 gcagttttgt aatgtagagt ttgcaaaaat gaccgatata atcaaacatc gtggtattgt
     4921 ggaaaacatt gaaggttctc atgtgcgggt gagaatcgta caaacttctg cctgttcggc
     4981 ttgtagtgtg aaagggcatt gcaatgcatc tgaaagtaaa gagaaactga ttgatgtttt
     5041 tgacatgaag gcatcttctt accgcatagg tgaggaggtg atgatttatg gtaccacttc
     5101 catggggatg caagccgtat tgctggcttt tggtatccct ttcttggtat tgctgattac
     5161 tttatttatt tccatgcgtt ttacgggggg ggatgagtta aggtcggcgc ttgttgcttt
     5221 gtcagccttg ctcccgtatt accttatcat atatgtatgc aggaataagt tgagcaagaa
     5281 gttttcattt acgcttgaac caataaaaaa taattaataa ataactaact aaaatttatg
     5341 gatttaattc tggttgcagt aatttcgttg ggagcgattg gcttgattgc cgcggtaatc
     5401 ttgtatgccg cttctaagaa gtttgctgtg tatgaagatc cgcggattgc caaggtgagc
     5461 gaagtgcttc ctcaggcgaa ttgcggtgga tgtggttatc ccggttgctc tggttttgct
     5521 ggtgcctgcg tgaaggctgc cgatgccggt tcgctggagg gtaagttatg tccggttggt
     5581 ggtgctccgg taatggagaa agtagctgcc attttgggat tggaagccgt tgctgccgaa
     5641 ccgaaagttg cggtggtaag atgtaacggt agttgtgaaa atcgccctcg tactgctctg
     5701 tatgacggag ctaaatcgtg tgccatcgct catgccactt caggtggtga gacgggttgt
     5761 acattcggtt gtctgggttg tggtgattgt gtggaagtgt gtcagtttga tgctattcac
     5821 atgaatcctg aaaccggcct tccggaagtg gacgaagaaa aatgtacagc ttgtggggct
     5881 tgtagcaaag cttgtccgcg taagatcatt gaaattcgtc cgaaaggaaa gaacaaccgc
     5941 cgcgtagtgg tgatgtgtgt gaacaaggat aagggagctg ttgccaacaa ggcttgcaag
     6001 gctagttgta ttggttgtgg aaagtgtgtg aaagtgtgtc cgttcgaagc cattacgtta
     6061 gagaataatt tggcatacat tgatccggct aagtgtaaat cttgccgtaa atgtgaatcg
     6121 gaatgcccga aaggggctat ccaagctatt aatttcccgc cacgtaaacc gaaggtagaa
     6181 gtgccggctg gtgaggctgc tgcaaaacct gctgcaaaag tagaggcttc aaaggtggaa
     6241 actccggaag cggtgaaagc tgaggctccg aaagcggaag cataatcaaa attcaaagta
     6301 agtaaaaatt aaaaagatat aacagtgaag acatttagaa ttggtggagt acatccagca
     6361 gaaaataaat tgtcagcagg caaagccatt gaaacccttg cacttcctaa gcaagcggta
     6421 tttcctttgt cacagcatat cggtgctcct gctactgcca tcgtgaaaaa aggcgatgtg
     6481 gtgaaggtag gtacgaagat tgctgaggcg ggtggctttg tttcagcagc catcttctcg
     6541 tctgtatccg gtaaagtgaa caaggtagac gccgtaatcg atgcaagcgg ttaccgcaag
     6601 ccggctatct ttatcgatgt ggatggtgac gaatgggaag aatcaataga ccgcagttcg
     6661 acattggtga aagagtgtgc tctcacaccc gaagaaatcg ttgctaaagt gaaaaatgca
     6721 ggtgtagtag gtatgggcgg tgcttgtttc cctactcatg tgaaactttc tcctcctccg
     6781 ggctgcaagg cggaatgtgt aattatcaat gctgtagagt gtgagcctta cctcactgcc
     6841 gatcatcgtt tgatgttgga aaaggcagac gaagtactgg tgggtgtaag catcctgatg
     6901 aaagctgcaa aagtgaccaa gggatatatc ggtattgaaa ataataaacc ggatgctatt
     6961 aagttgatga ctgaaaaggc tgctcagtat cccggtatag aggtggttcc tttgcaggtg
     7021 aaatatccgc aaggtggtga gaaacagttg atagatgctg tgatcggtcg ccaggttcct
     7081 gctcctcccg ctattcctat caatgtgggt gcggtagttc agaatgtagg tactgcattt
     7141 gccgtttatg aggccgttca gaaaaacaaa cctttgtttg aacgcattgt aaccgttaca
     7201 ggtaagtctg tcagaaatcc atctaatttt ctcactcgta tggggactcc gatgagccag
     7261 ctgattgatg cggctggcgg tttgcccgaa gatacgggaa aagtgattgg tggtggtccg
     7321 atgatgggta aagcactggt taatacagaa gttcctattt gtaaaggtag ttcgggtgtg
     7381 ctgattatga atgataagga agctgcccgt gcggaagctc agccctgtat ccgctgtgcc
     7441 aagtgtgtta acgtgtgtcc catgggactg gagcctttct tattggcaac actttcagct
     7501 cataaggatt gggagagagt agagaaagaa gatgtaatgt cgtgcatcga gtgcggttcg
     7561 tgtcagttta catgtccgtc tcatcgttat ttgctggact atatccgttt gggtaagggc
     7621 acagtaggcg gtattatccg tgcacgtaat gctaaaaaat aattcgacaa aatagtatgg
     7681 ctaataaatt aatagtatca ttatcgcctc acgttcatag cggtgacagc atacagaaga
     7741 atatgtatgg tgtactcatt gcgttgatac ctgcgttgct ggtgtcattt tatatgttcg
     7801 gactgggcgc cgtggtggtg accttgacct cggttgccgc ttgtgtattc ttcgaatggg
     7861 cgattaccaa gtttattttg aagagagaac gctctaccat ctgtgatggt tcggctatta
     7921 taaccggtgt gttgctggca ttcaatctgc cttccaactt gccgctttgg attattatca
     7981 tcggtgcgtt ggtggcaatc ggtgtgggca agatgacttt cggcggatta ggttgtaatc
     8041 cttttaatcc tgcgttggta ggtcgtatct tcttgctgat ttcttttcct gtgcagatga
     8101 cttcatggcc gttggttcaa caatggggaa gttataccga tgctgaaacc ggtgctactc
     8161 cgctggcatt gatgaaaatg gctgtaaagg gtgatgtaaa tgctttaggt cagttgcccg
     8221 atacattaag tctgtttctg ggtaataacc cgggttcgct aggtgaggtg agtgcattgg
     8281 ctttattgct tggcctggga tatatgctat ggaaaaagat tatttcctgg catattcctg
     8341 tatctattct ggtgactgta tttgtatttg ccggtctgat gcatttggtt gatccggtgg
     8401 cttatgcatc tccgttggct cacttgttta caggtggttt gatgttgggt gctattttca
     8461 tggcaaccga ctatgttact tcgcctatga ctcataaagg tatgattata tacggtgtgg
     8521 ctatcggttt cctgaccgtg gttatccgtt tgttcggtgc atatcccgaa ggtatgtctt
     8581 tcgctatatt cattatgaac gcatttactc cgttaatcaa tacttattgt aaacctaaaa
     8641 gattcgggga ggtcgtgaag aaatgaaaaa actagaatca tctttgaaaa acatggttat
     8701 cgtgctgaca gcgattactg tgattgcaac cggacttttg gcttatgtca accaactgac
     8761 tgccggtcct attgctgagg ctaatgcaaa agctttgagt gacgctattg cagttgtagt
     8821 tccggggttt gataacaatc ctgcggaagc tcctgaaact atagaattgg atggtgctac
     8881 ttataaaata tataaggcaa ccaagggtgg cgaatttatt ggtgctgccg tagaatcttc
     8941 tgccaatggt tttggtggcg ctttgagtgt gctggtaggt tttgacaaag agggaaatat
     9001 catagactat tctttgttga gccatgctga gactccgggc ttggggtcaa aggcggctga
     9061 ttggtttaag aaaggtgcaa aaggcgacat taccggtatg aatccgggac agggagcatt
     9121 ggtggtaaat aaggatggtg gtcagataga tgctatcaca gcttctacca tcactacacg
     9181 tgcttttcta aaagctgtga acaatgctta tgcagcatat agtggtcaga atgtggatgg
     9241 cgctagtggt gcaactcagc aagtgtctga aactgttgcc gaaaatgcta ctgcctgcga
     9301 tgctcaatgt gaaggaaacg aggcatgtaa gcaggtttgt gactctacag cctgcaagac
     9361 tgtttgtagc gataaatgtg atcctgctaa ctgcgataag gcagactgca aaaaagtaga
     9421 atgtcccaag caagattgta aaaataaaaa ataaggaagg agcagactat gaataatttt
     9481 aaagtattga tgaacgggat tgtaaaagag aatcccacgt ttgtactcct tttgggtatg
     9541 tgtcctacat taggaacaac atcttctgcc atcaatggta tggggatggg attggctacg
     9601 gcttttgtat taatctgttc taatgttgta atttcggcca ttaagaattt gatacctgat
     9661 atggtgcgca ttccggcctt tgttgtggtt attgcatcat tcgtaacctt gttgcagatg
     9721 attatgcagg catatgtgcc ggcactttat gctactttgg gcttgttcat cccattgatc
     9781 gtagtaaact gtattctgct gggacgtgcc gaagcttttg cagcaaagaa cggtcccgtg
     9841 ccttcattct tcgatggact gggtatgggg ctcggattta ctcttgcatt gactatcctt
     9901 ggtggtgtac gtgagttcct aggcacaggc aagttgtttg atatcactat catgcctgag
     9961 caatacggaa tgttgatttt cgttctcgca ccgggagcct tcattgcatt gggatacctt
    10021 attgcgattg tgaataaact gaagaaagca taacccgtaa aaagtaagaa tatggaatat
    10081 atattgatat ttatcaccgc tatatttgtg aacaacattg tgttgtcaca attcttgggt
    10141 atctgcccgt tcctcggtgt atccaaaaaa gttgagacag ctacgggtat gggtgcggct
    10201 gttgcattcg tgcttaccat cgctaccatt gttacctatc ttatccagaa atttgtactc
    10261 gatgctttcg ggttggaata tttgcagacc attgcgttta tccttgtcat tgcagcattg
    10321 gtacagatgg tggaaatcat attgaagaaa gtgtctcctg ccctttatca ggcattagga
    10381 gtattccttc cgttgataac cactaactgc tgtattttgg gtgtagctat cttggtcatt
    10441 cagaaagatt ttgatttgtt gactggcgtg gtttacgcct tctctacagc tcttggtttt
    10501 gctttggcta tggtattgtt tgcaggtatc cgtgaacaat taagtttggt gaatatacct
    10561 aaaggaatgc agggaatggc tatcgcattg gttactgccg gtctgctggc aatggcattc
    10621 atgggatttt caggtgtaga caaaggtttg ggtgttctgt ttggaataga atagttcact
    10681 tcatcgttaa aataaaccga ttcagaagtc cggagcacag cttcggactt ttttattaga
    10741 aagaaatcca ttgttcttgt ccgtaaattc aatttttatg cttatttttg cattagaatt
    10801 aatagagaga ttaaatggct atgaccttga ttgtactcgc ggccactatg gggaataaat
    10861 atggtggatt gaaacagctg gagggaatag gtcctaatgg cgaaacaata ttagattttt
    10921 ccatatatga tgccgtaaga gtcggatttg ataagatcgt atttgtcata agcagacatt
    10981 ttgaacaaga attcaagaaa ctggtatcag gcaaatatga acatgtggta gaagtggagt
    11041 atgtttatca ggatgtggaa acgattcctg aagaaaagcg taatccgaaa cgcaaagcac
    11101 tgtacggctc ggtaagagct gttttgatgg gagaagagtt gattgactct ccattcggtg
    11161 tgataaatgc cgtgaacttt taccaaagag aaagttttga attgttatat gataatctgg
    11221 tgatgttggg agaagctgac taccatagtt tcaatatttg ctacaggctg agaaatgtat
    11281 tggcggaaag cggaggggtt acccgtggta tttgtgaagt ggatgaaaag ggatatctgt
    11341 tgtccgttac agaccgtgta ggagtagaac ggataagtgg aaatccgatg tatcctaatg
    11401 aattacataa atgggtagct ttggatgaca acagcttggt ttcaatgaat atgtggggat
    11461 ttactccgca ggtatttggt gagatgaaga aggcgttcga taagtttata gatgagaatg
    11521 gaatggatat gaaagctcat tattctattc cggcttttat gaatgagcgt attgctgacg
    11581 gagtcagggt gaaagtgatt gagacacctg ccagatggat ggggttggta tcgcatgatg
    11641 acaagataca agtcctgctt cgtatcaatg atatgatacg aaaagggatt tacccgtcga
    11701 agttgttttg aacctattag aaaacgacag aatattaagt attatgaaag aaagaatttt
    11761 agtaacagga ggaaccggct acatcggttc tcatacggta gtagagctgc aaaatagcgg
    11821 ttacgacgta gtgattgtgg acaatttgtc caattcaagc gccgatgtgg tagataatat
    11881 agaaaaggtt tcaggaatcc gtcctgcatt tgaaaagttg gattgcttgg attttgaggg
    11941 aatggacaag ctgtttacta aatatccggg cataaaaggt attattcatt ttgcggctag
    12001 caaggctgtg ggtgaatcgg tacaaaaacc gttgttgtat tatcgcaata acttggtttc
    12061 attgattaac ctgttggagt taatgccgaa acatggagta gaaggtatta ttttttcatc
    12121 atcatgtacg gtgtatggtc agcccgatgt tcttcctgta acggaagagg ctccgattaa
    12181 gaaggctgag tctccgtatg gtaatacaaa acagatcaat gaagaaatta ttcgtgatac
    12241 agttgcttcg ggatcgccta ttaatgctat tatgttgcgt tactttaatc ctattggcgc
    12301 acatcccact gcattaatag gtgaattacc taatggtgtt ccacaaaact tgttacccta
    12361 cgttactcag acagcaatgg gtattcgtga aaaactgagt gtgtttgggg atgattatga
    12421 tacaccggac ggttcttgca tccgtgacta tatatatgta gtggatttgg cgaaggctca
    12481 cgttatcgca atggatcgca ttttgaataa caagcagaag gagaaggtgg aagtctttaa
    12541 tattggaacg ggtaaaggcg tttctgtatt ggaactgatc aatacatttg aaaaagctac
    12601 cggtgtgaaa cttaattatc agatcgtggg tcgtcgtgcc ggagatattg agaaggtatg
    12661 ggctaatcct gacttcgcta ataaggagtt gggatggaag gcagaagcca atttggagga
    12721 cacgctacgt tcggcttgga actggcagtt gaagctaaga gaaagaggaa ttcaataaaa
    12781 attaagatat ttttagaaag accgatgaac aaaggacgct agtgtggcgt tttatagatg
    12841 caaataacct gaaacccctc ttggatatgt gaatacctga ttggcggtag ttatgttact
    12901 caaaacatag agcaggctaa aaaattgcat agtagttttg tcgtgtttta ttttgtgttt
    12961 gtgttgtg
//
