LOCUS       c00157_gnlPro..        12385 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KADMCNAI_157.
ACCESSION   c00157_gnlPro..
VERSION     c00157_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:27:38
            Original ID  :: gnl|Prokka|KADMCNAI_157
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12385
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12385
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7723:12385]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7724..12385
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..12385
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12385
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..1204
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg157_1"
                     /sec_met_domain="Peptidase_U32 (E-value: 5e-20, bitscore:
                     61.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KHLLSLKDMNRSDQLEALLDAGASSFKIEGRLKDVTYVKNITAYY
                     RKKLDAILARRPEYCRASAGKSTYEFEPVAEKSFNRGFTPFFLHERTKDIAAFNTPKSL
                     GEPVGTVKELKGNSFTIAGVKQLNNGDGLVFFNSRGELEGFRVNRVEANRVFPLDMPDI
                     KPKTPLYRNFDQVFEKQLAKPSAERKLAVKIEFLDNPFGFTLVMEDETGARVMLTEPFD
                     KELARRDQADNIRTQLAKLGNTPFEASEVHIGMGENWFVPSSLLADMRRKAVEKLQSDR
                     MIRYQRELSRKVEPAKEVPFPERQLTYLGNVSNSRAEAFYKAHGVETVADAFELKPEKD
                     VPLMFSKHCLRYSMGWCPTYQKEKSPYKEPYYLLYKDTRLRLQFDCKRCQMLVYEAPSQ
                     K"
     CDS             1251..2069
                     /locus_tag="ctg157_2"
                     /transl_table=11
                     /translation="MKQQLFAFLLVLFTLISCGDKPLDPSKPVYVTVKTTMGDVTVLLY
                     DDTPLHRDNFIRLCQSGEYEGMLFHRIIKDFVVQGGDPTSKAHEPGVLYGDGDGGYTVP
                     AEILPNHFNKRGALIDAKESDDVNPERASAGTQFCFVQGKKHSDAELDEKEVRINQIRR
                     NWLYYKFLDRLKKEDPALAADSLETELTNRALVMVEDTLADLGPYVIPAEHREVYKTVG
                     GVPHLDSSVTIFGEVVDGFDIVEKMSLVKTDKNDRPIRDVMIKSTKVFQK"
     CDS             2224..2874
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg157_3"
                     /sec_met_domain="Epimerase (E-value: 2.8e-12, bitscore:
                     36.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVIIGATGYVGSAILKEALGRGHQVKAIVRDPSKLTLIHPHL
                     KVVGGSVTDTDFLSRELAKSDAVISAFNPGWSNPNIYEETLEGYGSILCAVRNSGVHRF
                     LMVGGAGSLLVAPGRQLMDEPDVPKKLLPGIRGMAKVYTDLLLPEKSVDWVFLSPAANM
                     APGERTGKFRLGKDELIVDESGDSNISVEDFAVAMIDELEQEKHHQERFTLGY"
     CDS             2985..3611
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg157_4"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-09, bitscore: 27.5,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKNIVFDLGGVFIDLDHDQAVRRFKEIGVEDAEQLLDPYEQK
                     GIFLEVENGTISADEFCQKLQEHTGKDLTYEDIKSGWLGFIADTPQYKLDYVLKLREHY
                     SVYLLSNTNPIIQEGWARTNEFTPAGRPIGAYFDKMYTSYEVGVTKPDRRIFDYMIKDS
                     GLIPAETLFVDDGKSNIEVGRTLGFITYQPQNREDWREAIDALLK"
     CDS             complement(3627..5984)
                     /locus_tag="ctg157_5"
                     /transl_table=11
                     /translation="MDKRLTSNKSLANYQYLMDTIWTIYLEDGSVEIQKDSMIPELENT
                     KHDYVILNNTIKNDVYPPDHILWDETVSLEAFHKMIAEGCFHKKFDMRFCNKHFGFEWH
                     EAFIDILTNKEGIPDRVVLSSHNVNDFRKSQIIETAVKAEYDYVIYIEASKNSYVMYTS
                     STESETPPPVASSNYEAVVAEYNRQYMEPEFCDAMTEKMSIAHVDPILRQHGEYILYGT
                     MIENGEKREKKMRFSYFDREQNIWLMTRTDITEIKEERKQKLLLQEALQSATAANRAKS
                     DFLSRMSHDVRTPINAIVGMTAIAGLHMNDQNRIADCLKKITISSKLLLNLINEVLDMS
                     KLESGKIMLTEETFKLDELLESLFIMVQSAFEAKKQKLVIHSKVKHECLIGDVQRIQQA
                     LLNMLTNAIKYTPNKGLIQISVEEKPSVYNGYGQFEIAVTDNGIGMKPEFLSKVFEPFE
                     RSDDKAIRNIQGTGLGMAISRHIAQMMNGDILVESEYGKGSKFTMRFHVKLGGMDEYDN
                     NLLIDLPVLVVDDDDISCEIACENLQELGMKPEWVLSGQDAVQKVSDGNKYFAIIIDLM
                     MPNMNGIETTYKIRECVGPDVPIIIISAYDYSDYEIEALKAGVNGFICKPIMKSKLFLL
                     MKKFATNKKEEEEVTIVPSIVASFPGKRILVVEDNDLNREIAYELLQETGAEIETASDG
                     LEAVNKVSASPEGYYDFIIMDIQMPVMDGLEATRQIRLLDRQDTKDLPIVAMSANAFAE
                     DVRLSLEAGMNEHIAKPIEIDRLYSVMGKWFR"
     CDS             complement(5998..6360)
                     /locus_tag="ctg157_6"
                     /transl_table=11
                     /translation="MTSEYKEKLQAYGVNLDSALNRFMDNEQFYERILSKFPMDENFIL
                     MERSLNENNISQAFRHAHTLKGLAATLDLTNISDILIPMTEKLRAGESEGIQDLFDQLK
                     VQYKLICDLITEHKAR"
     CDS             complement(6661..7701)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg157_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 5.9e-50, bitscore:
                     160.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYDVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIKLDLKDKEGTREALKAHPGINGIILFAASKAVGESVQQPLKYYRNNV
                     VTLVNLLELMPEFNIEGIVFSSSCTVYGQPDPENLPVTEDAPIKPATSPYGNTKQINEE
                     IIRDTIHANAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAIGIRKELSV
                     FGDDYDTPDGSCIRDYINVVDLAKAHVIAMDRMLGGKTEENVEYFNLGTGNGVTVLELI
                     NTFEKATGVKVPHKIVGRREGDIEKVWANPERANKVLGWTAKETLSDTLASAWKWQEKL
                     RERGIQ"
     CDS             complement(7724..8296)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 3e-66, bitscore: 212.5,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDKFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALVIFAGIREQLALTRVP
                     EGMKGTPIALITAGLLAMAFMGFSGIV"
     CDS             complement(8315..8899)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 9.2e-71, bitscore:
                     227.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGLGMGLGFTLALTLLGATRELLGTGKLFGLTLMP
                     EQYGSLIFVLAPGAFIALGYLIAIVNKLRKA"
     CDS             complement(8892..9497)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_10"
                     /sec_met_domain="FMN_bind (E-value: 3.2e-25, bitscore:
                     78.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FDNKPSEDAYMAVTGDGDSLKIYPATKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSTGPLKVTKDGGNVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             complement(9530..10489)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_11"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 4.7e-120,
                     bitscore: 390.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVVACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLLGKMGGSLGEVSALALLLGLVFMLWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(10502..11833)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_12"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 1.8e-17, bitscore: 52.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 5.9e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.2e-32, bitscore: 101.0,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.2e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVTNPSNFLVRMGTPISALIEAAGGVPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             complement(11846..12385)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 40.4; E-value:
                     1.1e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_13"
                     /sec_met_domain="Fer4_7 (E-value: 2.4e-13, bitscore: 40.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4e-12, bitscore: 35.5,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.2e-10, bitscore: 28.9,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 7.6e-09, bitscore: 25.3,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.6e-07, bitscore: 20.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="YGDCESACTFDAIHVNPTTGLPEVDEDKCTSCGACVKACPKNIIE
                     LRKKGPKSRRIFVSCVNKDKGAAARKACANACIGCGKCVKECPFEAITLENNVAYIDYR
                     KCRLCRKCVAVCPTGAIHELNFPPRKEAAPAVDADKVKPVTPKAASTPKAEAPTKVEAA
                     PATAPETITKEETTQK"
ORIGIN
        1 caaacatttg ttatcactca aggatatgaa ccgttccgac caactggaag ccctgctgga
       61 tgcgggtgct tcttctttta aaatagaagg gcgcttgaaa gatgtcactt atgtaaagaa
      121 tataacggct tattaccgga agaaactgga tgctatccta gcacgtcgtc cggaatattg
      181 ccgtgcatcg gcgggtaaga gtacctatga gtttgagccg gtagccgaga aaagtttcaa
      241 ccggggattt actcctttct tcctgcatga acgtacaaaa gatatagcag ctttcaatac
      301 tccgaaatcg ttaggtgaac ctgtcggaac cgtcaaggaa ctgaaaggca attcgtttac
      361 catcgccgga gtgaagcaac tgaataatgg ggatggcttg gtattcttca atagtcgcgg
      421 tgagttggaa gggtttcgtg tcaacagggt agaggcgaat cgtgtctttc cgttggatat
      481 gccggatata aagcccaaga cgcctttgta tcgtaacttt gaccaggttt ttgaaaagca
      541 gttggcgaaa ccttctgccg aacgtaagct ggctgtaaag atcgaattcc tggataatcc
      601 tttcggtttt acattggtga tggaagatga aacgggagca cgtgtgatgc tgaccgagcc
      661 gttcgataaa gagctggcac gtcgtgacca ggccgacaat atccggacgc aacttgccaa
      721 attggggaac acgccgtttg aagcatcgga agtacatata ggaatggggg aaaactggtt
      781 cgtcccgtcg tctcttctgg cggatatgcg tcgcaaggcc gtagagaagt tgcagtcaga
      841 tcgtatgatc cgttatcagc gtgaactctc gcgtaaggtt gaacctgcga aagaggttcc
      901 ttttccggaa cgccagttga cttatctggg gaatgtatca aatagccggg cggaagcttt
      961 ttataaggcg catggagtag agacggttgc agatgctttc gaattaaagc cggagaaaga
     1021 tgttccgttg atgtttagca agcattgctt gcggtatagc atgggatggt gtccaacgta
     1081 tcagaaagag aagtcacctt ataaggaacc ctattacctt ttatataagg atacccggct
     1141 gaggttgcag tttgattgta agcggtgtca gatgctggtg tatgaagcac ctagtcaaaa
     1201 gtaacaatca attctgataa tgactgcatt aataataaaa acgactcgtt atgaaacaac
     1261 aactattcgc ctttttactc gtcttgttta ctttgatctc ttgtggcgat aaaccgctgg
     1321 acccttcgaa acccgtttat gtgacagtga aaacgactat gggagatgtt actgtcctgt
     1381 tgtatgatga cactcccttg catcgtgata acttcatccg gttgtgccag tcgggtgaat
     1441 atgaggggat gctatttcac cgtatcatta aagactttgt tgtgcaaggc ggtgatccga
     1501 ccagcaaagc ccatgaacca ggtgttttgt atggagacgg tgatggaggt tataccgttc
     1561 ctgccgagat acttcccaac catttcaata aacgaggtgc tctgatcgat gccaaggaaa
     1621 gcgatgatgt aaatcccgaa cgtgcatcgg ccggaactca gttttgtttt gtgcagggga
     1681 agaaacattc tgatgctgaa ctggatgaga aagaggtacg gatcaaccag attcgccgta
     1741 actggttata ttataaattt ctggaccggt tgaagaaaga agacccggca ctggctgccg
     1801 actctttgga aacggaactg acaaaccgtg ctttggttat ggtggaggat acattggctg
     1861 acctgggccc gtatgttatt cccgccgaac accgcgaagt atataagacg gttggcggag
     1921 tgccccacct ggatagttcc gtgacgatct tcggagaagt ggtggacggt ttcgatatcg
     1981 tagagaaaat gtcgctggtg aaaacagata agaatgatcg gcctatccgg gatgttatga
     2041 tcaaatcgac gaaagtattt caaaagtaac tagtccccat acttggcacg gggccgcata
     2101 agggctgtct gtatcaattg ataataggat atatgggcgg tgcctttgcg atcccgtgtc
     2161 aggcacggga acagtttgcc atcgtatgtt gttctataga aagtaatcaa acaacataca
     2221 gtcatgaaga aaatagttat cataggcgcg accggctatg tcggatccgc tattctgaaa
     2281 gaagcattag gcagagggca tcaagtaaaa gccatcgtca gagatccgtc gaaactgact
     2341 ttaatccatc cgcatctgaa agtcgtggga gggagtgtga ccgatacgga ctttttatcc
     2401 cgcgaactgg ctaagtcgga tgcggtgatc agtgctttta atccgggctg gtcgaatccc
     2461 aatatttatg aagagacact ggaaggctat ggctctatcc tttgtgccgt tcgcaactcc
     2521 ggtgtgcatc gtttcctgat ggttggcgga gcaggcagtt tgttggtggc tcccggtcgt
     2581 cagctgatgg atgaaccgga cgttcccaag aaacttttac caggaatacg agggatggca
     2641 aaggtttata ccgatttgtt gttgccggaa aagtcggtgg attgggtttt cctgagtcct
     2701 gcggctaata tggcaccggg agagcgtacc ggaaagttcc gtctgggaaa agatgaactg
     2761 attgtcgatg aaagtgggga tagcaatatc tccgtagaag atttcgctgt agccatgatt
     2821 gatgaactgg aacaggaaaa gcatcatcag gagcgattta cactcgggta ctaagtgtct
     2881 ttggcaaaaa cagttgcagt cattcgaata gttgttgctt tacacttatt atgcttatct
     2941 ttgtcaggaa gtagagataa agatagatgt aaaaagagat aattatggca aagattaaaa
     3001 acattgtatt tgatttagga ggagttttta tagacctgga ccatgatcag gcagttcgtc
     3061 gtttcaaaga gatcggggtg gaggatgcgg aacagttgct ggatccttat gagcagaaag
     3121 gtatctttct ggaagtagaa aacggtacga tcagtgctga cgagttttgc caaaagcttc
     3181 aggagcatac ggggaaggac ctgacgtatg aagatataaa atccggttgg ctgggattta
     3241 tcgccgatac gcctcaatat aagctcgatt atgtgttgaa acttcgcgag cactacagtg
     3301 tttatctgtt gagcaatacc aatcccatca tccaggaagg gtgggcaagg acaaacgagt
     3361 ttactccggc aggtcgtccg atcggtgcct attttgacaa aatgtacacc tcgtatgaag
     3421 tcggcgtaac gaaacccgac cggcgtatct ttgactatat gatcaaagac agcggactga
     3481 ttccggcaga gacgctcttt gtggatgatg gtaaaagcaa tatcgaagta ggacgtacat
     3541 tgggcttcat cacctaccaa ccccaaaaca gggaagattg gcgtgaagct atcgatgcgc
     3601 tgttgaaata aaccgattgg gggtattcaa cggaaccact ttcccataac actgtaaagc
     3661 ctgtctattt ctatgggttt ggcgatatgt tcgttcattc cggcttccag gcttagccgc
     3721 acgtcttcgg caaaagcgtt ggccgacatg gctacgatcg gtaagtcctt ggtgtcttgc
     3781 cggtcgagaa gacggatttg ccgggtggct tcaagaccgt ccatgacagg catttgtata
     3841 tccataatta tgaaatcgta atatccttca ggggaagcgg aaaccttgtt tacggcttcc
     3901 agcccgtcgc tggctgtttc aatttcagca ccggtttcct gtagcaattc ataagcgatc
     3961 tcacggttca ggtcgttgtc ttccacaacg agtatccgtt tgcctgggaa agaggcgacg
     4021 atagatggta cgatagtgac ctcttcttcc tcttttttgt ttgtggcaaa ctttttcatc
     4081 aggaggaaca gtttggactt catgataggc ttacagatga aaccgttgac cccagctttc
     4141 aaggcttcga tttcgtagtc ggaatagtcg taagccgaaa tgatgatgat aggaacatcc
     4201 ggtcctacgc attcccgtat tttgtaggtt gtttcaatgc cattcatgtt gggcatcatc
     4261 aggtctatga tgattgcaaa atacttgttc ccgtcgctta ctttctgtac ggcatcctga
     4321 ccggaaagaa cccattccgg cttcatccct aattcttgca ggttttcaca ggctatttcg
     4381 caggatatat catcatcatc cacaaccaat accggcaggt ctattaatag attgttgtcg
     4441 tattcatcca tgcctcccag tttgacatgg aatctcatgg tgaatttgga accttttcca
     4501 tattcgcttt ctaccaggat atccccgttc atcatctggg cgatatgacg actgatcgcc
     4561 ataccgagtc cggtaccctg gatattgcgg atggctttat cgtccgaccg ttcgaacggc
     4621 tcgaatactt tgcttaagaa ttcaggtttc atccctatgc cattgtccgt gacggctatt
     4681 tcaaattgcc cgtaaccgtt ataaacggaa ggtttctcct cgactgaaat ttgtattagt
     4741 cctttgttcg gggtatattt gattgcattt gtcagcatat tcaacagtgc ttgttgtatg
     4801 cgttgtacgt caccgatcag gcattcgtgc tttactttgc tgtgtattac taacttttgc
     4861 ttttttgctt caaaggccga ctgcaccatg ataaataaac tttccagcag ttcatcgagt
     4921 ttgaatgtct cttccgtcag catgatctta ccgctttcga gcttcgacat atccagtact
     4981 tcgtttatca ggttgagcag gagcttggaa gatatggtta tcttcttcag acaatcggct
     5041 atgcggttct ggtcgttcat atgaagaccg gctattgccg tcatacccac gattgcattt
     5101 atgggagtac gtacgtcatg gctcattcgt gacaggaagt ctgacttggc acggttggcg
     5161 gcagttgcgc tctgtagggc ttcctgcaac aatagcttct gttttctctc ttccttgatt
     5221 tcagttatat cggtcctggt catcaaccag atgttttgtt ccctgtcgaa gtagctgaat
     5281 cgcattttct tttcacgttt ttcaccgttt tctatcatgg taccatataa aatatactct
     5341 ccatgctgtc gcagtatcgg atcgacgtgg gcgatactca ttttctcggt cattgcatca
     5401 caaaattccg gttccatata ctgtcggttg tactctgcaa ctaccgcttc atagttactg
     5461 ctggctaccg gaggaggagt ttcgctttcc gtactggaag tgtacatgac ataactgttt
     5521 ttagatgctt cgatataaat cacatagtcg tattctgctt ttacggctgt ttcaatgatt
     5581 tgtgatttcc tgaaatcatt aacattgtgg ctggagagga caaccctgtc gggtatgcct
     5641 tctttgttag tcaagatatc tataaaggct tcgtgccatt caaaaccgaa atgtttgtta
     5701 cagaaacgca tgtcgaattt tttgtggaaa catccttcgg ctatcatttt atggaaggct
     5761 tcaagcgaaa ctgtttcgtc ccataaaata tggtcaggcg gatagacatc attctttatc
     5821 gtgttattga gaatgacgta atcatgtttc gtattttcca actccggaat catggagtct
     5881 ttctgtattt cgacacttcc gtcctccagg tagatagtcc agatagtatc catgaggtat
     5941 tggtagttag ccaatgattt atttgatgta agcctcttat ccatgcagtt tgttttatta
     6001 tcttgctttg tgttcggtaa tcaggtcgca gattagtttg tattgtactt tcaactgatc
     6061 aaacaggtct tgtatacctt cactctctcc ggctctgagt ttttccgtca tcgggatcaa
     6121 tatgtccgat atatttgtca ggtcaagcgt tgccgccagt ccttttaatg tatgggcatg
     6181 tctgaaagcc tgggaaatat tattctcatt gaggcttctt tccatcagga tgaagttttc
     6241 atccataggg aatttggaga gtattctttc ataaaactgt tcattatcca tgaaacggtt
     6301 taatgcactg tccaggttaa ctccgtacgc ttgtaacttc tctttatatt cgcttgtcat
     6361 gttttttatc gccatttata taacaaatca tctgtctgtt acgaaaggaa tccccaaaag
     6421 tagataaaaa atatatatgg agatggaaaa aacgttataa ttcaatagga atgtatgctt
     6481 ttttctgcta tttgacgaat ccgatcctcc gacgagcctg ttttgatgtc tgatgttggt
     6541 tttgaagctc agttgacgtt tcattgataa gttccggttg taatgtgggg gatcaagaaa
     6601 aatgccggaa gaaatctctg gagaatcttc cggcatgctt atttaaaaaa gacttttctt
     6661 ttattggata ccgcgttcgc gcagtttttc ctgccatttc caggcagaag ccaatgtatc
     6721 ggacaatgtt tctttagcag tccatcccaa taccttattg gcacgttccg gattagccca
     6781 aactttttcg atatcacctt cgcgacgacc tacgattttg tgaggaactt ttacaccggt
     6841 agctttttcg aatgtattga tcagttccaa caccgttaca ccgttaccgg ttcccaggtt
     6901 gaaatattca acattttctt cagttttacc acccagcata cggtccatag cgattacgtg
     6961 tgcttttgcc aggtcgacta cattgatata gtcgcggata caagagccgt caggtgtatc
     7021 atagtcatca ccgaatacgc tcagttcctt gcggataccg attgcagtct gtgtcagata
     7081 cgggatcagg ttctggggaa caccgttagg caattcgccg atttctgcac tcgggtgagc
     7141 accgatcggg ttgaagtaac gcaggataat gctcttgaac ggagcgtttg cgtgaatagt
     7201 atcgcggatg atctcttcgt tgatctgttt ggtgttgcca taaggagaag tagccggttt
     7261 gatcggggca tcttctgtta caggcaggtt ttcaggatca ggctgtccgt aaacggtaca
     7321 ggaagaagag aatacaatac cttcgatatt aaattccggc atcagttcca gtaggtttac
     7381 cagtgtaaca acattgttac ggtagtactt cagcggctgc tgaaccgatt cgccaacagc
     7441 tttgcttgct gcgaaaagga tgataccgtt gatacccgga tgagccttca atgcttcgcg
     7501 ggttccttct ttatctttta aatccagttt gatgaattca ggacggatac ctgtgatctt
     7561 ttcaatgcca tccaacactt cgatattgga gtttgacagg tcgtcgatga taacaacatc
     7621 ataacctgca ttctgcaact caactgtagt gtgtgagcca atatatccgg ttccacctgc
     7681 tactaagatt ttctttttca tgctagtctc tatttagatt aaattatacg attccggaga
     7741 atcccataaa cgccattgcc agtaaaccgg ctgttatcag cgcaataggg gtacctttca
     7801 taccttcggg aacacgtgtc aaagccaact gttctcttat ccctgcaaag ataactaaag
     7861 ctagcgcaaa tccaatagct gttgatattg catatacaac agattctaat aaattatatt
     7921 ctttttgtat tacgaggatg gcgacaccca aaatacagca gttggtggtg atcagcggaa
     7981 gaaacacgcc aagtgcctgg taaagagccg gagaaacctt tttcagaatg atctcgacca
     8041 tctgaaccag tgcggcgatg atcaggataa aactgatggt ctgcataaag cccagtccga
     8101 acttatccag gatatatttc tgcaccagga aagtaacgat ggttgcgatc gtcaacacga
     8161 atgttactgc tgcacccata ccggctgccg tttccacctt tttcgatacg cccaggaacg
     8221 gacagatacc caggaactgc gccaacacta cgttgttgac gaatacggct gcgataaata
     8281 ttagtatata ttccatatct ttcgtttttt aatatcaggc tttacgcaat ttattaacaa
     8341 tagcaatcag gtaacccagc gcgataaagg cacccggagc caatacaaag atcagcgaac
     8401 catattgttc gggcatcagt gtcaggccga acagtttacc tgttcccagc agttcgcggg
     8461 tagctccgag caaggtaagt gccagcgtaa agccgagtcc catacctaat ccgtcgaaag
     8521 cggaaggaat cacaccgttt ttagcggcaa atgcttccgc acgtcccagc acaatgcagt
     8581 ttacaacaat caacgggatg aacaatccca ggctggcgta aagagccgga acgaatgctt
     8641 ccatgcacat ctgcacgacg gttacgaatg ttgcgattac gacaataaag gccggaatac
     8701 gtaccatgtc ggggatcagg ttcttcaagg ctgaaataac catattggaa cagatcagaa
     8761 cgaacatggt tgccagtccc atactcatac cgttcaatgc tgaagaagtt gttcccagag
     8821 ttggacacat acccagcaac aagacaaatg tcgggttctc tttgatgata ccgttcatca
     8881 atactttcat attactcatt gtcgtttcct ccctcgttag tgttagcggt tgttgcaccg
     8941 gttactccgt cagttccggc gaatgcgctg taagcacggt tcaccgcatc cagaaatgca
     9001 cggctggtga tggttgctgc tgtgatagca tccacgttgc caccgtcttt agttactttt
     9061 aatggtccgg tggacaggct gcgtcccaaa acgctttgtt tattcttgtc cgtactgaac
     9121 cattcctgca ttttagctcc cagaccggga gtttccgcat gctgtaatac ggaatagttc
     9181 aataacttgc cttccttatc gaatccgacg atcactttga tctctccgct gaatcctttt
     9241 tttgtattac tttcgacagc tgcacctacg aactctccgc ctttggtagc cggatagatt
     9301 ttcagggaat cgccgtcgcc tgtaactgcc atataagcgt cctctgacgg tttgttgtcg
     9361 aattcaggtg taacagcttt gatagcagct tccagcgcag cagctttgga ggctgcaatc
     9421 gggccggtgg tgtacatatt tactccggct aatatcgctc ccgcaaccaa acagatgatg
     9481 gtaagcgaca agagcatatt gggtaatgtt gattttagtt ttgccatgct tatttccctc
     9541 caaaatgttt aggtttgata taactgttga tcagcggggt aaatgcattc ataataagaa
     9601 tagcaaacga cataccttcc ggataagaac caaacagacg gataacggta gtcagaatac
     9661 cgataccgac accgtaaacc aacataccgt tcttactcat gggcgaagtc acatagtcgg
     9721 ttgccataaa gatggctccc agcatcagac ctcccgacag caggtgaacg aatggacttg
     9781 cgtattgtac cggattaacc aggtgcataa tacctgtgaa tacaaatacg gtcagcagga
     9841 tagaaaccgg aatctgccag gtaataatct ttttccataa cataaagacg agtcccagca
     9901 gcaatgccag tgcacttact tcaccaaggc tgccgcccat tttacctaac aacatatcta
     9961 ccagggtagg caacttgtcg agtgcccctt cgttcatcag tgataaaaca gttgcaccgg
    10021 tggttgcgtc ggtgtacgct gtcagctgtc cgacttccgg ccacatcgtc atctgtgccg
    10081 ggaaagagat cagcaggaat acacgtccga ctaatgccgg gttaaaaata ttgttaccca
    10141 gtccgccaaa tgacatctta ccgataccga ttgctgccag tgcaccgatc aggatgatcc
    10201 atacaggcag gttcgacggc aggttgaatg ccagcagtac accggtcagg atagccgaac
    10261 cgtcacatac ggtcggttcc tttttcatca ggaacttctg gatcagatat tcaaagagga
    10321 cgcaggctac gaccgatgtt gcagtaacga tcagcgcacc cagcccgaag tagtagaggg
    10381 ataccaggaa agccggaaca agggcaatca gtacaccata catatttttg cttatgctat
    10441 cgccgccgtg gatatggggc gaaggagata ctattaaatt attttccata ttgctctgtt
    10501 tttatgactt tcgtgcccgt atgataccca ttacctttcc tttacccgaa cggatataat
    10561 ccagcaacgg acggttggcc gggcaggtat aactacaaga accgcactcg atacagtcgg
    10621 tgatataatt cttctcggcc aaatcccatt ctgcaaattc tgttgcattc atcagcaggg
    10681 tagggttgag gcccatcgga caaacgctga cacatttggc acagcggata cagtcgcgca
    10741 tcggtttgcg gacagactct tcttttgtca ggagcaatac gcctgaacta cctttcgtta
    10801 ccggtacttc cggagcaatc agggcttttc ccatcatcgg gccgccaccg attatctttc
    10861 ctgtattttc aggaacacca ccggcagctt caatcagtgc actgataggc gtacccatac
    10921 ggaccaggaa gttggaagga ttggtaactg ctttacctgt cacggtaacg acgcgttcaa
    10981 acaaaggttt gtttttcatt accgcttcat acactgcaaa agcagttcct acattttgta
    11041 ctacagctcc ggcggaaata ggcagtgcac cgctcttcac ctgacggcga atcacagcat
    11101 cgattaattg cttttcacct ccttgcggat actgtacttt cagcggcata atctcgatac
    11161 ctttataggc tgtagccagt ttactcagat gagcgatggc gtcaggcttg ttgttttcga
    11221 taccgatcac tgcttttgtt acatttacag ctttcatcaa cagcgtaacg ccgaccagaa
    11281 tctgctctgc cttctccatc atcaatgaat ggtcggaagt cagatacggc tcacattcta
    11341 cggcattgat aatgatgatc tcggctttgc ttccgggagg cggcatcagt ttgacctgtg
    11401 tggggaatgt cgcaccaccc agacccacga taccggctgc ggcgatcttg tctacgatct
    11461 ctttggaagg aagcgggcac tctttcacga gcgtttcgct gcggtcgatc gactcttccc
    11521 attcgtcacc ttccacatca atatagatag cgggacgttt gtatccgctt gcgtcgagag
    11581 cgttatctat cttgtttact ttaccggata ccgacgagtg gatattcgcc gatacaaaac
    11641 ctccggcttt ggcgagaagc gtacctactt taaccgtatc acccttcttt accacagcct
    11701 gggcaggagc cccgatatgc tggcttagcg gtataataac ctgcttgggt atagccagtc
    11761 cggttatttt cttcccggca gacaatttat tttcgggtgg atgtatacct ccgattcgaa
    11821 atgtccttag catactatta gatttttatt tttgagttgt ttcttctttt gttattgttt
    11881 caggcgctgt tgccggtgca gcttcgactt ttgtcggtgc ttcggcttta ggggtcgatg
    11941 cagctttagg cgttactggc tttactttgt cggcgtccac agcaggggcg gcttctttac
    12001 ggggcgggaa gttcaattcg tgaattgctc cggtcggaca tactgctacg catttacggc
    12061 acagacggca tttgcggtag tcgatataag ccacgttgtt ttcgagcgta attgcttcga
    12121 acggacattc tttcacacat ttaccacaac cgatacaagc gttcgcacat gctttacggg
    12181 cagcagctcc tttgtctttg tttacacagc tgacgaagat acggcgtgat ttcggtccct
    12241 ttttgcgcag ttcgataatg tttttcggac aagctttgac gcaggctccg catgaagtac
    12301 atttgtcctc gtccacttcc ggcagtccgg ttgtcggatt gacgtggatg gcgtcgaagg
    12361 tacaggcact ttcgcagtcg ccgta
//
