LOCUS       c00085_gnlPro..         8895 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FGCCJLKM_85.
ACCESSION   c00085_gnlPro..
VERSION     c00085_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 05:22:00
            Original ID  :: gnl|Prokka|FGCCJLKM_85
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8895
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8895
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[979:5122]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      980..5122
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..8895
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..8895
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(7..198)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg85_1"
                     /sec_met_domain="IlvN (E-value: 3.5e-12, bitscore: 35.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIDRKSVV"
     CDS             complement(248..973)
                     /locus_tag="ctg85_2"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(980..1534)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_3"
                     /sec_met_domain="ALS_ss_C (E-value: 2.1e-17, bitscore:
                     52.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(1550..3253)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.4e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAKKPFCLVGQGVLLGG
                     AEEELRAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVE
                     KREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
     CDS             complement(3287..5122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg85_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-217, bitscore:
                     711.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSFSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSFT
                     QFVPGHTHLHEIGQLVKAEIEKQGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTVFVSGGPMEAGELDGRHLDLID
                     AMIESADTSVSDERIEQVERHACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     KNRIQLFRDAAKQIVENAYKYYRDGDDSVLPRNIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAVAQEAGADFHMEDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGILGIMNELMKAG
                     LVDGSTRRADGLTLAEAVDKYAVTSPNVTEEAIRKYKSAPAHRFSIQMGSQESYYKELD
                     TDRAEGCIRDVEHAYSKDGGLAVLRGNIALDGCVVKTAGVDESIWKFSGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAASGGAIGLVRDGDIIEINIPERSINVRLSDEELAERRKAEEARGKK
                     AFTPPTRQREVSKALRAYGKMVSSADKGGVRIVED"
     CDS             6202..7419
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg85_6"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-43, bitscore:
                     138.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LTPIAIKKLIVNKNMKHYNFDEVIERHGTSCVKFDRLKEMFGDEN
                     LIPLWVADMDFRTPDFIVEALKKRCEHEIFGYTFGSDEYYESIINWVHYKHNWKIQREW
                     ISYIPGIVKGIAFAIQCFTQKGDKVIIQPPVYHPFRIVPEKMKREVVYNPLKMVDGIYE
                     MDFDHLESIIDDKCKVLILCNPHNPGGIVWKKETLVRLAEICTKHNILVISDEIHAEMA
                     YPQYTHYPFASVSDTAASCSVTFMAPSKTFNIAGIVTSYAIVPNDRIREEFYSFLEAGE
                     FGDGTIFAYTATTAAYTYGAEWLQQMRMYIMENVRFVEEFMKLHLPKIKVYQPQASFLV
                     WLDCRELELSQDELVHLFKDKAGLALNDGSIFGPGGEGHMRLNIGCPRSVLDKAMNALK
                     KAVDKK"
     CDS             7468..8043
                     /locus_tag="ctg85_7"
                     /transl_table=11
                     /translation="MKITANKYVAVTYDLNVGEGEERELMEKATVEAPLKFIYGTGMML
                     PAFEKALNGLEVGGTFNFSIEPAEAYGEYNEEHVLDLPKNIFEVDGKFDAEMIKEGNTV
                     PMMDSNGNRMNGSVLEVKDDIVVMDFNHPLAGETLHFSGEVIDVHEPTAEEIAAFSAPA
                     GGCSCGCDDCGSDCGDNHEGGCGCGGCH"
     CDS             8147..8881
                     /locus_tag="ctg85_8"
                     /transl_table=11
                     /translation="VNTFGNIYRLTSFGESHGPGIGGVIDGCPAGIELDTAFIQQELNR
                     RKPGQSRITTPRKEDDEVQFLSGXXXXTTGTPIGFIIWNKNQHSSDYDNMKTVYRPSHA
                     DYTYQTKYGIRDPRGGGRSSARETIARCVAGAIAKLALKQYGIQIQAYTSQVGPIQLAG
                     SYQDYDLSLTEESDVRCPDPKTASEMETLIAEVKSKGDTIGGIITCVAKGVPVGLGEPV
                     FGKLHAALGHAKIGRASCRERV"
ORIGIN
        1 tcttccctac acgacgctct tccgatctat tacgttgaag ccattgtcac gaaggttcaa
       61 tgactgtccc ggtccctgta cgccatagcc gataacagcg attgtctcat cttttaatat
      121 ctctcttgcc ttttccaacg gaaattcctc gcgggtcatt acattctcta caacaccgcc
      181 aaaattcatt tgtgccattt tctttttaac tattaatgtt taaaaaccta tttatgtatc
      241 tcttttatta tctccaagta accgccgcac gacagatcgc ctttccctca tggcaaatag
      301 ccatgtcttg cttatcggga gcggactccg ccttatgaag cgtaagcggc ataccttgtt
      361 taccctcgga ttggtaggcg atctccagac ggccgatctc acgggtcttg aactgatcga
      421 tatcgaacaa atccagcagg tgctcgatat acttcacgct attgaagtga ccgttgatat
      481 ccaagtcgct gtatttgatc gaatacggga ttccctccgc cttattctcc gccggcatga
      541 tcttgcccgg cttctcgatc gggcacggac gctcgtcgat atatttgccc aatgcctcta
      601 tatccaataa ggtaggacgg cgggtctcca cgtcgatagc cgcccaaata gaacgggcga
      661 atccaaaggt tttcccattc tcatccgcca gctcgaaaca acgactggtg aagaggcgtc
      721 cgacctcatc gatccaagtg tatagattaa tcttatcgaa ggcggtagga tattccttca
      781 tctcgatagc cagacgggac aacacccaag ccgtatgacg ctccgacata tcattgaaac
      841 cgaacccacg ctctccggca tggctggaag cggcgtgaat caaatagtta ccaatcatag
      901 ggagcgttac acgtcccctg aaatccatca aatacggctc cgccacgaaa tgaaataatc
      961 ctactttctc catatcttat tattgttgct tttcatgtaa ctttcgctcc atatcggcca
     1021 acatatcgct caagcgctcc accttgctct tcgtgatagc cacacgtccg gagcggatga
     1081 attgcaggac accgatcgtc tcgctcaact cattgaacaa ggcttgtgtc tcgtcatagt
     1141 ggccactctt ctccaacacc acgcaggcct cgttcatctc caagatacga gcgttgtatt
     1201 tacggatcaa tccctccacg gttcccatct tgatgaaaag ctcggtactt agcttataaa
     1261 gggcgatctc ttgataaacc agatcctcat ccgtattata ataagccttc aagatatcca
     1321 cacgtttatc gatctgtttc accaccttat cgatcatatc ctcatcggcg aaggtcgtga
     1381 tcgtaaactt atggatgccc ttgatagcgg acggagagac ggacagagtc tcgatgttca
     1441 gctgtcggcg tgtaaagata atcgttatct ggttcaaaag acctacgata ttctctgaaa
     1501 agataataac ggtatataat ttctttgttg tcatagcttc atctcctcct tatttctcgt
     1561 ctcccataat catgtttgtc acgcttcccc cggcaggaac catcggatat accattccgc
     1621 aagtctccac gttagcgacc aacacgtaag cgccgtcgtg gtttagcatc tcggcgatag
     1681 cgtcgtccaa ttcctcccgc ttttcaacgg cacggccagc gataccatag gctttagcga
     1741 tcgccacgaa atccggattc tccatgatgg tgtttgaata acgctcgtgg aagaacaatt
     1801 cttgccactg acgtaccata cctaagaagt tattattaag aatgataatc ttcacgttca
     1861 gtttctcctg catgatggta cccaattcct gaatcgtcat ctgcataccc ccatcaccgg
     1921 taaagaagca gaccgtacgg tccggagccc cgaacttagc gcccatagcg gccggcagac
     1981 caaatcccat cgtacctaaa cctccggaag tcaccacgct acgggtttgt ttatatttga
     2041 aatagcggac acccatcatc tggttctgcc caacgtcggt caccaataca gcgtcgttac
     2101 cggtcgcctc ggaaacctta cggactacct cgcccatttt cagttggccc tcggtcggat
     2161 acaattcctt ctcgattacc ttatcgtatt cctctttctc gtcccgatcg aactcggcat
     2221 tccattccgg acgtttacgt tcttccaaca acgccgtgat catcggtatc gtgtgcttgg
     2281 cattacccag cacctttaca tctacgggga cgttcttacc gatttccgag ttgtcgatat
     2341 ccagatggat aatcttggct tgcttagcgt atgtctttaa atcgccagtc acacggtcgt
     2401 cgaaacgcat accgatagcg atcaatacat cacactcatt cgttttccgg ttcggcccta
     2461 cgtttccatg cataccgagc attcccttgt tcaatgggaa atcggttggc aacgcagata
     2521 agcccaatac cgtagatccg gcaggtatat cattcttttg gagaaacgct ctcaattcct
     2581 cttccgcacc gcctaacaat actccctgcc cgaccagaca gaagggtttc ttcgcctcat
     2641 tgattaaatc ggcggcggcc ttgatacgat cctttttgat atccggctcc ggctgataac
     2701 tacgtacgta atctaccttc ttatattcat agtccaccag ccctacttgc gcgtccttcg
     2761 ctaaatccag cacaactgga cccggacggc ctgtagaagc gatataaaaa gcacgagaaa
     2821 cagcccatgc gatctcctcc ggcttgcgga tttgataagc ccatttcgtg atcggttgcg
     2881 tgatgccaat cacgtcgact tcctgaaaag catcggttcc caacaacggc gagggtactt
     2941 gaccggcgat tacgaccatt ggcgtactat ccatcagcgc atcagcgata cccgtgatgg
     3001 tattcgtagc gcccgggccg gaagtaacca acgtcactcc taccttgccg gatacacggg
     3061 catatccttg agccgcatgg gtagcgcctt gctcgtggcg caccaataca tgcctcaact
     3121 ggtccctata atcatataaa ctgtcgtaaa taggtatcgc ctgtccgccg ggataaccga
     3181 agatagtatc tactccttca gcaatcaacg ctttcagcaa agcttccgaa ccggttatct
     3241 tttgtttctc cataagaaat aacgtgttta atgtatatta ttggctttaa tcttcaacaa
     3301 tccttacacc tcccttatcg gcggagctaa ccatcttccc gtacgctctc aacgctttcg
     3361 agacctcacg ctgacgcgtc ggcggcgtaa aggctttctt tccacgcgcc tcttccgctt
     3421 tacggcgctc ggccaactcc tcgtcgctca gccgcacgtt gatggaacgt tccgggatat
     3481 tgatctcgat gatatccccg tctctcacca gtccgatagc gccaccggaa gcggcctcag
     3541 gagagatatg cccgatagaa agaccggacg taccgccact gaaacgacca tccgtgatca
     3601 aggcgcactc cttacctaag tgacggctct ttatataaga ggtaggatat aacatctctt
     3661 gcattcccgg ccctcctttc ggaccctcat acgtgatgac gaccacatcg cctgaaacga
     3721 ccttgcctcc taaaatgccc tcgcaagcgg catcctgtga atcgaagact ttcgccgggc
     3781 cggagaattt ccaaatactc tcatccacgc cggcggtttt tacgacacat ccgtccaagg
     3841 cgatattccc tctcaaaaca gccaagccgc catccttgga ataagcgtgc tccacgtcac
     3901 ggatacaacc ttcggcacga tccgtatcta attccttata ataagattct tgggaaccca
     3961 tctggatact gaaccgatga gcgggagcgc tcttgtattt acggatcgcc tcctccgtta
     4021 cgttcgggga agtgacggcg tatttatcaa cagcctcggc caaggtcagg ccgtccgcac
     4081 gtctcgtgct gccatccaca agcccggctt tcatcaactc gttcatgata ccgaggattc
     4141 caccggcacg gtttacgtct tgtacatgat aagtgtgcgt attcggggct accttacaca
     4201 ggcaaggtgt cttgcgggat aacatatcga tatcctccat atgaaaatcg gcgccggctt
     4261 cttgtgccac ggccaataag tgaagcaccg tattggtaga cccccccatg gcgatatcca
     4321 gcgacatggc gttcaagaaa gcctgacggg tagcgatgtt gcgaggtaac acggaatcat
     4381 ccccgtcacg atagtatttg taagcgttct caacgatttg cttagccgca tcacggaaaa
     4441 gttggatacg gttcttatgg gtagccacga tcgtcccgtt ccccggaagc gccagaccga
     4501 tcgcctcgtt caagcagttc atagagttag cggtaaacat accggaacaa caaccgcaac
     4561 ccggacacgc atggcgttcc acctgctcga tacgctcatc gcttaccgat gtatcggcgg
     4621 actcaatcat cgcgtcgatc aaatccagat ggcggccatc cagctcacct gcctccatcg
     4681 ggccaccgga cacgaacacc gtcgggatat ttaatcgcat ggaagccata agcatacccg
     4741 gcgtgatctt atcgcaattg ctgatgcaaa ccatagcgtc cgccttatgg gcatttacca
     4801 tatattccac gctgtccgcg ataatgtcgc gtgaaggaag cgagtaaagc atcccatcgt
     4861 gccccatagc gataccgtcg tcgatagcga tcgtattaaa ttcagcggcg aaacaacctt
     4921 gtttctcgat ctcggccttg accagttgcc cgatctcatg caaatgcgta tgccccggca
     4981 cgaactgggt aaatgaattt acgatagcga taataggctt gccgaactgt tcctctttca
     5041 tcccgttggc acgccatagc gcacgggctc cggccatcct acgaccttcg gtgctaaatg
     5101 agcttcttaa cggattcttc atctctttcc tattttttgt tcgtagagcg ctttatccac
     5161 gcctctacct tgatttattt ataataaaaa agcctttccc tatatggaga aaggcttaag
     5221 aaatatctct acgacttcac aacttcttac acacctttct ccttacctac taatgactag
     5281 aaggaccacc acgagaataa tatgcaatac gttgttcatc atcttttctt attgtctttg
     5341 tttgtttgac gctgcaaatg tagaacaata attgatatgc gcaaaggatt taaaagaaaa
     5401 ttcttcattt ttctttcaat tctcaagcaa ataccatttt aggattgcat tttaacagga
     5461 gcaagagtgt attacttagg aatcggaagg tatagaaggg aaaaaacttc gatttccaaa
     5521 cagaaacagt aaaaagacaa atgttatcta aaacagattc cagataacat ttttatcaga
     5581 taacacgact tacgataaca cgtatctcat aagaaaatcc tattctagcg ataaaaaaga
     5641 tacatataaa ctctaaatca catatttatt aacacttgta gactataaat agccttgaaa
     5701 aaattcataa tagtgttcta gaaaaaacat aaggaagttt tctgaagaac ataaggaata
     5761 aatttcatct agtatcggac taaattttgt taacattcga atgaaaatca cctaaaatca
     5821 agactaaatc cggcataacc cacgctagaa gcagctcaag caaagacatt ttcaaaatga
     5881 ctttcagaca gagaaagcct taaatactca accgatagac agctattcaa acatcaatca
     5941 taaaaaagac caacaacacc tgcattcaaa catcattctg atttacacaa ccatcaaatg
     6001 cttgcgcttt ttccgtgcga ccaagccccc gccccataat tcatcaccca cagagagcaa
     6061 taataacact ttgacatttt gccagttcac ggtttgataa gccatttaag taaacgattc
     6121 attaaatata tcgccgattt cctaatatac agcatttcat actttgattt ggataaacaa
     6181 taaatataat aatttgtatc tttgacccca atagcaatta agaaactgat cgttaataaa
     6241 aatatgaaac actacaactt cgacgaagtt atcgaacggc atgggacgag ttgcgtgaaa
     6301 ttcgaccgtt tgaaagagat gttcggtgac gagaatctga taccactatg ggtggcggat
     6361 atggatttcc gcacaccgga ctttattgta gaggccctga agaaacgttg tgagcacgag
     6421 atattcggct atacattcgg ctccgacgag tattacgaga gtatcatcaa ttgggtacac
     6481 tacaaacata actggaaaat acaacgggaa tggatcagct atatcccggg aatcgtaaag
     6541 ggaatcgctt tcgctatcca atgctttacg caaaaaggag ataaggtcat catccagccc
     6601 cctgtttatc atccgttccg catcgttccg gagaaaatga agcgtgaggt cgtttataat
     6661 ccgctaaaga tggtagacgg catctatgag atggatttcg atcatcttga atctattata
     6721 gatgataaat gcaaggtatt gatcctctgc aaccctcaca atccgggcgg gatcgtctgg
     6781 aaaaaggaaa ccttggtccg attggccgag atttgcacca agcacaatat tttggttatc
     6841 tccgatgaga ttcatgcgga aatggcctat cctcagtata cgcattatcc atttgcctcc
     6901 gtatcggata ctgccgcttc ttgcagcgta actttcatgg caccgagcaa gacgttcaat
     6961 atcgccggta tcgtgacttc ctacgcaatc gtacccaatg atcgcatccg ggaagaattt
     7021 tactctttcc ttgaggccgg agagtttggc gatggcacga tcttcgctta tacggcgaca
     7081 accgccgctt acacctatgg cgccgaatgg ttgcaacaaa tgcgaatgta tatcatggag
     7141 aatgtacgtt tcgtggaaga gttcatgaaa ctacatctcc ccaagataaa agtttaccag
     7201 ccccaagcct ccttcctcgt ttggttggat tgcagggaac tggaattaag tcaagatgaa
     7261 ctcgtacacc tgttcaaaga caaagccgga ctagcgctga acgacggaag tatcttcggt
     7321 cccgggggag aaggccatat gcgtttgaac attggttgcc cccgctctgt tttagataaa
     7381 gcgatgaacg ctcttaaaaa ggcggtggat aagaaataaa atcgtatctt tgcgagcatt
     7441 tctatacata tttaaaatac aagacaaatg aaaattacag caaacaaata cgttgcggtt
     7501 acatacgacc tgaacgttgg cgaaggtgaa gaacgtgagt taatggaaaa agcgacggtc
     7561 gaggctcctt tgaaattcat ctacggaaca ggcatgatgc ttccggcatt cgagaaagcc
     7621 ttgaacgggc tggaagtagg tggcacgttc aacttctcca tcgagccagc cgaggcttat
     7681 ggcgaatata acgaggagca cgtattggat cttccgaaga atatcttcga ggtggacggt
     7741 aaattcgacg ccgagatgat caaggaaggt aataccgtac cgatgatgga ttctaatggc
     7801 aaccgtatga acggctctgt attggaagtg aaggatgata tcgtggtaat ggacttcaac
     7861 catccgttgg ctggcgagac tttgcatttc agcggcgagg taatcgacgt acacgaaccg
     7921 acagcggaag agatcgcagc cttctccgct cccgcaggtg gatgtagttg cggttgcgac
     7981 gattgcggta gcgattgtgg cgataaccac gagggtggtt gtggttgtgg tggatgccac
     8041 taaataatgg gaaattgaga attgaaaatt gaaaattagg agaagtgcct aatcatcggc
     8101 ttttgattct caattttcag ttttcaattt tcaattagac aaaacggtga atacttttgg
     8161 taatatttat agattaacat cgttcggcga atcgcacggc cccggtatcg gcggcgtgat
     8221 cgacggatgc ccagccggga tcgaattaga tacggcattc atccagcaag agctgaaccg
     8281 tcgtaaaccg ggacaatccc gtatcacgac cccccgtaaa gaggatgatg aggtacaatt
     8341 tctttccggc nnnnnnnnnn agacaaccgg tacgccgata ggtttcatca tctggaacaa
     8401 aaaccaacat tcctcggact atgacaatat gaaaacggtt taccgtcctt cccatgctga
     8461 ttatacctat caaacgaaat atggaatccg tgatccccgt ggaggtggac gttcgtccgc
     8521 ccgggaaacg atcgctcgtt gcgtggctgg ggccatcgct aaactcgccc ttaagcaata
     8581 cggcatacag atccaagctt atacctcgca ggtcggcccg atccaattag cgggtagtta
     8641 ccaagattat gatttaagct tgacggagga gagcgacgta cgttgcccgg acccgaagac
     8701 cgcctcagag atggaaacct tgatcgccga ggtcaaatca aaaggagata cgatcggcgg
     8761 tattattacc tgtgtggcga aaggggttcc cgtcggattg ggagagcctg tgttcggcaa
     8821 gttacatgcc gcgttgggac atgcgaagat cggaagagcg tcgtgtaggg aaagagtgta
     8881 gatctcggtg gtcgc
//
