LOCUS       c00169_gnlPro..         6186 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NENKFPGP_169.
ACCESSION   c00169_gnlPro..
VERSION     c00169_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:44:58
            Original ID  :: gnl|Prokka|NENKFPGP_169
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6186
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1347
                     /locus_tag="ctg169_1"
                     /transl_table=11
                     /translation="PFRGELNNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDY
                     MAEMIVSVNRMGDGEETELVLSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKI
                     GKPGKQDDFNVYLYSLEVTRPETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQ
                     SGEPLAYEDAVNNFDVDRFARTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTK
                     RDLVADLSDALGKYGIRLILYYHVGHGDKEWWDKQHYTRDNAGDLFTNVEKIVGEISQR
                     YGNRLAGLWMDDGIGYYPNGASFEKIAKAAKSGNKELAICFNSWILPKLTDFQDYYAGE
                     LGLSLASAGVNDPSLPLDGDGLFHGGPQDGLQATFSGTLEPGDWTHIYKDSIIGDPVLS
                     IDELTQVVKESNKRKNLPMINVRIYQDGTISPKSYALLKELNNRISKGE"
     protocluster    1..6186
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1717:5960]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1718..5960
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..6186
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6186
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             1718..3553
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_2"
                     /sec_met_domain="ILVD_EDD (E-value: 1.5e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             3694..5184
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-36, bitscore:
                     113.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQL
                     KHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAGQ
                     VPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLDL
                     AKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGGA
                     EEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIGM
                     RFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERKR
                     PEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQMM
                     GVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELGT
                     IMQENLNVKIIVLNNNFLGMVRQWQGSCSSTNGIRIPS"
     CDS             5181..5393
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-10, bitscore:
                     28.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPDFVAIAKAFGIASRAVDKREDLDEAIAEMLNHDGAYMLVAN
                     VETCGMVYPMVPAGGSVTNMILGDK"
     CDS             5406..5960
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg169_5"
                     /sec_met_domain="ALS_ss_C (E-value: 6.7e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             5997..6185
                     /locus_tag="ctg169_6"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLMDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRP"
ORIGIN
        1 ccttttcgtg gagaactgaa taatggtgtg aaacaacttt atccggaaga accttataaa
       61 gcattctggg cggagaactg gaaaactccc gagcagtcaa tatcctggaa agtcaatacg
      121 gacggtgaag actacatggc tgaaatgatc gtttctgtca accggatggg agatggggaa
      181 gaaacggagt tggtattatc caatggaacg gacagtgtta tttgccggat aaatacaacc
      241 ggatggcagc gttgccggtt cccccgtcct ttacatttta ataaggggac ttccgtttta
      301 tctttaaaga ttggcaaacc cggtaagcag gatgatttta atgtgtatct gtactcgttg
      361 gaagtcaccc ggccggagac ttatgagcag ctgcgggcgg aagctacatc acttcgcagt
      421 aatacatcct ggatggcgga tttgccttat ggctttttct tccactggaa ttcaaagagt
      481 atgcctcagt caggagagcc gttagcctat gaggatgcgg tcaataactt tgatgtggac
      541 cgctttgcac gaactgttta cgaatgtggc gggaagttga tattttttac aacgtcgtgg
      601 gcggaatatt atttcccggc tccgatacag gcaatcgatt ctattttgcc ggggcgtacc
      661 acaaagagag atttagtggc tgatttatct gatgcgttgg gtaaatacgg cattcgtctg
      721 attctgtatt accatgtcgg tcatggagat aaagaatggt gggacaagca gcattataca
      781 cgggataatg caggagattt gtttacaaat gtggaaaaga tagtgggaga gattagccag
      841 cggtatggaa atcgtctggc cggtttgtgg atggatgacg gtatcggtta ttatcctaac
      901 ggtgcctcgt ttgaaaagat tgctaaagcc gccaaaagtg gaaataagga gttggcaatt
      961 tgtttcaatt cctggatatt gccgaagctg acggactttc aggattatta tgctggcgaa
     1021 ctgggtttgt ctttggccag tgccggtgtt aacgatcctt ctcttccgtt ggatggggac
     1081 ggattgtttc acggtggccc tcaggatggc ttacaggcaa ctttctccgg aacattggag
     1141 ccgggtgact ggacgcacat ttataaagat tccattatcg gtgatcctgt tctttccatt
     1201 gacgaattga cgcaggtagt gaaagaatct aacaaacgaa aaaatcttcc gatgattaat
     1261 gtccggattt atcaggatgg aacgatttct ccgaaatcgt atgctttgtt gaaagaactg
     1321 aacaatcgta tcagtaaagg agaatgaccg gaaattatcg aatatgaagc gaatggaggc
     1381 tcagaaataa gaattcaatt gattgagggc tggttatctg ttaaaatgca agatgaaccg
     1441 ccctcttttc ttgataaatg aaagaaaaag taagattttt cttttaaatc ctttgctcgt
     1501 acaaattatt attctacatt tgcagcgtca aacaaaataa agacgataag aaaagatgat
     1561 gaacaatgta ttacatatta ttctcgtggt ggtccttcta gtcattagta ggtaaggaga
     1621 aaggtgtgta agaagttgtg aagtcgtaaa agatatttct taagcctttc tccatataga
     1681 gaagggcttt tttattgact aaaagataaa aacagatatg atgaagaatc cgttaagaag
     1741 ctcctatagc acagaaggca gacgtatggc cggtgcccgt gcattatggc gtgccaacgg
     1801 catgaaagaa gaacagttcg gtaaaccgat cattgccatt gtgaattcat ttacccagtt
     1861 tgtaccgggc catgtgcatc tacacgagat cggacagcag gtaaaagcgg aaatcgaaaa
     1921 gctcggttgc tttgccgcag aatttaatac gatcgctatt gatgacggta ttgctatggg
     1981 acacgacgga atgctttatt ctctgccttc ccgcgacatc attgctgaca gtgtggaata
     2041 tatggtgaat gcgcataagg ctgatgcaat ggtttgtatc agtaactgcg acaagattac
     2101 tccgggtatg ctgatggcca gtatgcgtct gaatattccg acaatctttg tatccggcgg
     2161 tccgatggaa gccggtaatc tggacggacg tgcactcgat ttgatcgacg ccatgattga
     2221 agcggctgac gattctatca gcgatgaaca agtagaaaag gtggaacgtt ccgcttgccc
     2281 gacctgcggt tgctgttccg gtatgttcac ggctaactct atgaactgtc tgaacgaagc
     2341 gattggattg gctcttcccg gcaacggaac agttgttgca acacatgcca accgtactcg
     2401 cttgttcaaa aaagcggcga agatgattgt tgataatgcc tttaaatatt atcgtgacgg
     2461 cgatgattcc gtattgcctc gcagtattgc cacccgtcag gcctttctga atgctatgtc
     2521 gctggatatt gccatggggg gatcgacgaa tacagtcctt cacctgttgg ccgtggctca
     2581 tgaagcggaa gtcgatttta caatgaaaga catcgatatg ctttcacgca aaacaccggt
     2641 tatctgtaaa gtggctccga gttgttctta tcatgtggaa gatgtgaacc gtgccggagg
     2701 tatcatcggt attatgaatg agctggtaaa agccggtctg gtggacggtt ccgtgaaacg
     2761 tgcggatggt ctgactttga atgaggctat cgaccaatac tgcattacct ctgtaaatgt
     2821 aacggaagaa gcaatcaata tttataaaag tgctccggcc caccgtttca acctggtgct
     2881 cggatcgcag gaaagttatt ataaagaact ggataccgac cgtgcaaccg gatgtatccg
     2941 cgatgtggaa catgcttatg tgaaagacgg cggtctggct gttctgtatg gaaatattgc
     3001 acaggacggt tgtgtggtta aaacagccgg ggtagatgaa agtatcttcc gttttgccgg
     3061 ccctgccaaa gtattcgatt cgcaggatgc cgcttgcgaa ggtatcctga aagatcaagt
     3121 cgtctccggc gatgtcgtcg ttatcaccta tgaaggtcct aagggtggtc cgggtatgca
     3181 ggaaatgttg tatcctactt cttatataaa gagtaaacac ctgggtaaag aatgtgcgct
     3241 aatcacagac ggacgcttca gcggtggaac atcaggtttg tcaatcggac atatttctcc
     3301 cgaagcggct gccggaggag cgattggctt agtgaaagac ggcgatatta tcgaaattaa
     3361 tattcccgaa agaaccatac atgtaaaggt gacagacgaa gaactggcca aacgccgtga
     3421 agcggaagag gcccgcggaa caaaagcctt tacacctcct ttccgccaac gtacggtatc
     3481 gaaagcactg aaagcatatg caaagatggt tgcttcggcc gataagggcg gtgtacgaat
     3541 agtagaagat taattagtaa caaagagtat tctttcccct cttgagaggg gataaggggt
     3601 gtgttaaagt tcagctctat tggatagcat taacacaccc cctaccccct ctcaagaggg
     3661 gaaaggttac catcagacaa taaaacaaca aatatggaac aaaagataac cggttcggaa
     3721 gctttgctga aagcgctgat cgctgaagga gtagatacta tcttcggtta tccgggtggg
     3781 caggcgatac caatttacga tagtttatac gattacagag atcagttaaa acatattctg
     3841 gtgcgccacg aacaaggtgc aacacatgct gcacagggat atgcccgtgt ttccggaaaa
     3901 gtgggagtaa cggtggttac ttcgggtccc ggggcaacca ataccatcac tggtattgcc
     3961 gatgcgctga tggacagtac accgatggtg gtgattgccg gccaggttcc gtctccgctg
     4021 cttggaacag atgctttcca ggaagttgat gtaattggta tcacacaacc gattaccaaa
     4081 tgggcttacc agatacgccg cccggaagaa attgcttggg ccgtttcccg tgctttctat
     4141 atcgcatcga ccggtcgccc gggacctgtg gtactggatt tggcgaaaga tgcacaggtg
     4201 ggtttggtag attatgagta tcagaaagtg gattatgttc gtagttacca gcctgaaccg
     4261 gatatcaggg aggaacgtat cgaggcggct gcttcattga taaataatgc caaaaagcca
     4321 ttctgtctgg tagggcaggg ggttatccta ggaggagctg aagaagaact gaaagaattc
     4381 ttgttgaaaa acgatatacc agccggttct accgtattgg gcttgtctgc attaccttcg
     4441 gacttcccat taaataaagg tatgttgggg atgcatggaa atgtcggacc gaaccgcaag
     4501 actaacgaat gtgacgtgct gattgctatc ggtatgcgtt tcgatgatcg cgtaaccggc
     4561 gacttgaaga cttatgccaa gcaggcaaag attatccacc tggatatcga caattcggag
     4621 atcggaaaga atgtgccggt cgacgtgaaa gtgctgggaa atgccaagca tacgattccg
     4681 atgattacgg ctttactgga agaacggaag cgtccggaat ggaatgctga attcgaaccg
     4741 gatgaaaaag aggaatataa taaggtaata gaaaaagaac tctatcctac cgaaggccaa
     4801 ctgaaaatgg gcgaagtagt ccgtaaggtt tccgaagcaa ccgataatga tgcgattctg
     4861 gttacggatg taggtcagaa ccagatgatg ggtgttcgct atttcaaata taaacaaaca
     4921 cgcagcgtag ttacttcagg aggtttggga acgatgggct ttggccttcc cgccgccatt
     4981 ggagcgaagc tgggagcgcc tgaccgtacg gtctgtttct ttaccggcga cggtggtatc
     5041 cagatgacta tccaggagtt gggaactatc atgcaggaaa atctgaatgt aaagatcatc
     5101 gttcttaaca acaatttcct gggaatggta cgccagtggc aggggagctg ttcttcaacg
     5161 aacggtattc gaataccatc atgaagaatc cggattttgt agcgatagcc aaggcttttg
     5221 gtattgcttc ccgtgcggta gataaacggg aagacttgga tgaggcgatt gctgaaatgt
     5281 tgaatcacga tggtgcctat atgttggttg ccaatgtgga aacttgtggt atggtatatc
     5341 cgatggttcc ggccggagga agcgtgacaa acatgatttt gggtgataag taaggaggag
     5401 aaactatgaa tacaaaacaa ttatataccg ttattatctt ttcggaaaac actgttggtc
     5461 ttctgaatca gataactgtt atctttacgc gccggcaact gaacattgag acgctttctg
     5521 tttctccctc tgctataaag ggaatacata agtttacaat tactaccttt gccgacgagg
     5581 atacgatcga caaggtcgta aaacagatcg acaagcgtgt ggatatcctg aaagcttatt
     5641 ataatacgga tgaagacctg gtttaccagg aaatcgctct ttataaactg agtaccgaac
     5701 tctttatcaa gatggggacg gttgaggatc tgatccgtaa gtacaatgcc cgtatccttg
     5761 aaatgaatga ggattgtgtg gtgttggaaa agagtggtca ttatgatgag acacaggctt
     5821 tgtttaaaga attgagtgag acgatcggtg tcctgcaatt tatccgttcc ggacgcgttg
     5881 ctataacgaa gagtaaggta gaacgtctga gcgacatgtt atctgcaatg gaaaagaagt
     5941 tgcaggaaaa acatgtctga gaataataag gaaacatttt gtaaataaag taaattatgg
     6001 agaagaacaa agtaggagaa tttcatttcg taacagagtc ttatctgatg gacttccggg
     6061 gacgtattac aatccctatg atcggaactt atttgttgca tgctgcttct tgccatgccg
     6121 ccgaccgtgg attcggatat aacgatatga ccgaaaggca taccgcctgg gttctttccc
     6181 gtccgg
//
