LOCUS       c00064_gnlPro..        10619 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKDDDAKN_64.
ACCESSION   c00064_gnlPro..
VERSION     c00064_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:27:27
            Original ID  :: gnl|Prokka|DKDDDAKN_64
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10619
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..690)
                     /locus_tag="ctg64_1"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDVATATKTNEEVYNFLRDVSSRYGIGFWQPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKKPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTN"
     protocluster    1..10619
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2779:8861]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2780..8861
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10619
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10619
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             805..2718
                     /locus_tag="ctg64_2"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQVLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NAELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGNRILEEKIDIGIISPYKAQVQYLRNKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             complement(2780..3823)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_3"
                     /sec_met_domain="IlvN (E-value: 3.4e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.1e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(3874..4626)
                     /locus_tag="ctg64_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(4623..5183)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_5"
                     /sec_met_domain="ALS_ss_C (E-value: 5.4e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(5216..6967)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.6e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(7059..8861)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg64_7"
                     /sec_met_domain="ILVD_EDD (E-value: 2.4e-219, bitscore:
                     718.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHQLRSSFSTQGRRMAGARALWTANGMKKEQMGKPIIAIVNSFT
                     QFVPGHVHLHEIGQFVKEEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNGQHLDLID
                     AMIKSADESVGDKEVAQIEQHACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     ENRKKLFEDAARLIVENAFRYYEEGDESVLPRSIATREAFLNAMTLDIAMGGSTNTVLH
                     LLAVAHEAGADFKMDDIDMLSRKTPCLCKVAPNTQKYHVQDVNRAGGIIAIMDELAKGG
                     LVDTNVRRVDGMTLAEAIDRYSITSSNVCKEAIKKYSSAAAGKFNLVLGSQNASYKELD
                     TDRATGCIRDLEHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFTGPAKVFDSQDA
                     ACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDEELAARLMTPVTRNRE
                     VSKALKAYASMVSSADKGAVRLID"
     CDS             9351..9923
                     /locus_tag="ctg64_8"
                     /transl_table=11
                     /translation="METVENKYITVAYKLYSIENGEKDFEEEAPVEHPFQFISGLGMTL
                     EPFEAQIKDLQIGDKFDFTIPASEAYGEYDDDHVIDLPKEIFMIEGEFDSDRVVEGAVI
                     PLMTSEGQRINGSVVEVKEDIVVMDMNHPLAGCDLNFTGEVVESRLATNEELAEVARMM
                     GGGCGSCGCGDCGDGCGDHECGGGCCH"
     CDS             complement(10023..10619)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SDH_alpha"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg64_9"
                     /sec_met_domain="SDH_alpha (E-value: 5.5e-60, bitscore:
                     192.4, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="HKVMGDSVFSHILSYTSGACDARMAGAMIPVMSNSGSGNQGISAT
                     LPVLIYAEENGKSEEELIRALMLSHLTVIYIKQSLGRLSALCGCVVAATGSSCGITWLM
                     GGTYEQVAYAVQNMIANLTGMICDGAKPSCALKVTTGVSTAVLSAIMAMENRCVTSVEG
                     IIDEDVDQSIRNLTKIGSKGMNETDKLVLEIMTSK"
ORIGIN
        1 attggttccc ccttttacag taagaatacc cgccaacttc agaataacgt ctttgggagc
       61 tacccagcca ctcaatttac ccttcaagtg tacgcctatc agacgcggct ttttcagttc
      121 ccattccatg ccggtcatca catccaccgc atcggcacca cccacaccaa tggccaccat
      181 gcccaaacct ccggcattgg gcgtatgaga gtccgtgcct accatcattc cacccggaaa
      241 tgcgtagttc tccaatacca cctggtgaat aatgcctgcc cccggctgcc aaaaacctat
      301 accatagcgg gaagaaacat cacggagaaa attatagacc tcctcgttgg tcttcgtagc
      361 agtcgcaaca tcttcttttg cacctttata tgcttgaatc aaatggtcac aatgcacagt
      421 ggaaggcacg gcaacctgct cacggcctgc attcataaat tgcaataagg ccatttgagc
      481 cgttgcatcc tgcatggcca cacggtcggg acggaaattc acatagtctt ctccccgtct
      541 gtagttcttc actttatccc catcatacaa atgagcatac aaaattttct ccgctaaagt
      601 catcggacgc cgcagtacgt tccgtacgcg ttctatcttc tccgaataag cagcataaaa
      661 cgttttgagc atcgttaaat catataccat aaccactatt ttttagtttt tcattattgt
      721 aaagattaca aattaatatc ataaacaaat aaaaaggctg aatagtttaa caaaataaag
      781 cattttttcc gtcggaagcg aagaatgatt acctttgcaa ccatgaagga acaagattca
      841 aatagtccta ttattcacct ccagcagcaa caagttttgc tgcgcatgga atacgaatac
      901 gaaaaagagg aattcaaacg ccaaaccgaa aacatgggag ttgcccggaa agtgaaacgg
      961 ggactttgct ggtatcctgc cactccggga cgaagttact ataattcact gaatcaatta
     1021 gtaatagaaa ttacacacac agaaaatacc gatatagaac ataattttga gttcggccgt
     1081 cccgtatgtt ttttccgcca gtctgctgat ggaaaaataa cctatatgaa cttcaccgct
     1141 accgtaagct atgccgacga gacacggatg gtagcgataa tgcccggagc cggtgccgtt
     1201 atggaagtgc aggaaacgga caacctcggc gtgcaacttt atttcgacga aacatcctat
     1261 cggaccatgt tcgaagcctt ggaagatacg ttacgctcca aaggcaaccg cctggccgaa
     1321 ttgcgggaca tattgctggg aacctcgaaa gccggtttcc gagagctcta tcccgtacgg
     1381 tttccctggc tgaactccac gcaggagaca gctgtaaaca aagtgctgtg tgcccgcgac
     1441 gtggccattg tacatggtcc tccgggaacc ggaaaaacga ccaccttagt ggaagccatc
     1501 tacgaaaccc tgcatcggga accgcaggta ctggtatgtg cccaaagcaa tactgccgtc
     1561 gactggattt cggaaaaact tgtggaccgt ggcgtcaatg tcctgcgtat cggcaatccg
     1621 acccgtgtca acgacaagat gctttccttt acctacgagc gtcgtttcga gaaccatccg
     1681 ctttatccgg agctgtggag catccggaaa aatctccgtg aactgggcag ccgtgcccgc
     1741 cgtggcagct atgacgaacg cgaaggagta cgcagccgta tgagccgcct gcgcgaccgc
     1801 gccaccgcat tggaaataca aatcaatgca gagctttttg atggggcaca tgtcatagcc
     1861 tccacgctag taagcagcaa tcaccggctg ctgaacggac gccgtttcgg cacccttttc
     1921 attgatgaag cagcccaggc cttagaagct gcctgctgga tagctatccg aaaagcagac
     1981 cgcgtggtgt tggcgggtga ccactgccaa cttccgccca ctataaaatg ctacgaagct
     2041 gcccgtggag gtctggaacg aacattgatg gagaaagtgg tgtccaacaa acctgccgtt
     2101 gtctctttgc tgaaagtaca ataccgcatg cacgaggaaa tcatgaaatt tccttcccaa
     2161 tggttttata atggcgagtt ggaagccgct cccgaagtgc gttaccgggg catcctggac
     2221 tgggataccc ctatccactg gattgacacc tccgaaatgg atttcaaaga agaatttgtg
     2281 ggagagactt tcggacgcat caataaagcg gaagcggacc tgctcctatc agaactgaaa
     2341 atctacatca accgtatcgg tggcaaccgc attctggaag aaaaaataga catcggcatc
     2401 atctcccctt acaaggcaca agtgcaatat ctccgcaaca agataaaggc agacgcttca
     2461 ctcaagcctt atcgcagctt gttcactgta aatacggtgg atggcttcca agggcaagag
     2521 cgcgatgtta tcttcatcag ccttgtccgc gccaacgaag aagggcagat aggattcctg
     2581 aatgatttaa ggagaatgaa tgtagccatc acccgggcac gtatgaagct ggtgatattg
     2641 ggagaggcag agacgctgaa acatcacggt ttttaccgga agctattgga gtttattcaa
     2701 aatataggga atcaataata aagaaatacc ccctccggta acaccgaaga gggtatttca
     2761 cctatttata taaagctgat taattgtttt ccggacgaag tttacgaact gtaacagctg
     2821 tctgccacat ttcgctttca cgcaaggctt tcaattctgc attcagcttc tcacgataat
     2881 cgggtttgga gttactgtcg atagaaatct gagcttcgtt gcccgacttc acacttgcat
     2941 acaatttctg tacaaccggc ttgatggcat catggaacgg ggtcatccaa tccagcgcac
     3001 cacgctgtgc cgtagtagaa cagttggcat acatccagtc cataccgttc ttggcaaaca
     3061 atggcatcaa agattgagtc aactcttcca cagtttcatt gaatgcttca gaaggagtat
     3121 ggccgttttc gcgcaatact tcatactgag ccaacagcaa tccctggata gcacccatca
     3181 atgaaccgcg ttcaccggtc aagtcggaag tggcttcgcg gatgaaagtt gtctcgaaca
     3241 aatatcccga accgatgccg atacccagtg caatcgtctt gtcaaaagcc ttacccgtag
     3301 catcctgata gacggcatat gatgagttca agccacgacc ctcgaggaac atggtacgaa
     3361 gtgaagtacc ggaacctttg ggagcaacca taataacatc aatatcttta ggaggaacca
     3421 cgccggtacg gtcgttccag gtaatagcaa aaccatgaga gaagtaaaga gcctttccgg
     3481 gagtcaaata aggtttgata gtcggccata cagacattac agctgcgtca gacaacagac
     3541 acatgatgat agtacctttc tgacaagcct cttcgatgcc gaacaaagtc tcacccggta
     3601 cccatccgtc agccacagcc ttttcgtatg tcttacccgg acgttgtcct acaatcacat
     3661 tgaaaccgtt atcacgcaag ttgcaagcct ggcccgggcc ttgtacgcca taaccgatta
     3721 ctgcaattgt ttcatctttc aaaatctcac gtgctttttc caaaggaaat tcttcgcggg
     3781 tcattacatt ctcaataaca ccgccaaaat tcaattgtgc cattttttgt tttaattttt
     3841 atttgtggct tacgccaacg ttgataaatt tatttatttc tctgtaaata tcactttaga
     3901 gcgacagacc acttcgctgc cattcttttt cacctccaca tcgtaaacgc cctcaccggc
     3961 atcatccatg aacaaagtca actcatcccc ataatagctt tcggctacat atgccatttc
     4021 aaaacgacgg atgcgcttct ccttatacat ctctatcggg aacaaatcaa ggatatgctc
     4081 gatgtaacgg atgctgttca catgcccgtt aatgtcaata tcactgtatt tggctaccaa
     4141 agcagcaacc ggttcctttg aggccacctt tatccgcgaa ggtttttcta tcgggcaagg
     4201 ctcatcgcaa acataatcta caatgctgcc actatgaaga gccagcaaat ctgccggctt
     4261 acgggtattc atgctaatca tcgcccaaac ggaacgtgca tacccaatct tcttaccctc
     4321 cttatcgatg atagcgaaat tacggtctgt aaaaaggcga tagacattct ccacccaagt
     4381 ctgaatggag aaatcttcgt actgataagg catttcatcc agttcgacag ccagacggga
     4441 caatacccaa gtataattgt cctcgtttag agtcgcgatg ccaaaaccgc ggtcgctggc
     4501 atggaaaccc gcacaattca acaaatggtt gcccaatact cccattgtca gccgtccggt
     4561 aaagtcgaca tgaaacggtt cggcaacaaa cttgtaggta cctattttat tgttctcgct
     4621 catcatgatt cctggtgttt actttgacga tattttgctt cacggtccgc cagatattca
     4681 ttgacacgct caaagcagct ggtcgtaatg gctacgcgac ccgaacggac gaactgaagt
     4741 acgcaatcca actggcgcaa ctcctcataa agattggtta tttcctcact catgccattc
     4801 ttctcaacaa tggcaaatac agcattcacc tccacaatac gggcattgta cttacggatt
     4861 actttggaca cctccggttt ttcttccagc gtaggggtcg ttattttata aagggcaatc
     4921 tcgtgctgat agatttcatc atccgtgaaa taatgggctt gcagcacatc tattttcttg
     4981 gtaatctgct tggtcacctt ttcaatggta tccttatccg tccaagcggt aatggtatat
     5041 ttatgtaccc ccttgatgga ggaggccgat acattcaaac tctcgatgtt tatctgccgg
     5101 cgggtaaaca cagccgtcac ctgattcagc aaaccggcaa agttttccga atgaacaatg
     5161 attgtatata gttttttatc catagataga gtaaattctt taatttcgca tgacttcagc
     5221 attccaacaa catctgattg accgaaccgc ccggaggtgt catcggcatt acatttcctt
     5281 cttcctccac acaagcttcg agcaggaacg gtccgtcagt cgctatcatc tcgtcaatcg
     5341 cttttgccag ctcctcgcgg gtcattaccc tgcgtgcagg aatatcatat gccgaagcaa
     5401 tcttcatata atccggattc atcatcggag taaacgaata acgacgattg aagaacatcg
     5461 cctgccattg acgaacattg cccaagaagt tattgttcaa cagaatcatc ttcaccggag
     5521 ccttttgttc catgatggta cccagttcct gcaggttcat ctgcaagccg ccgtctccca
     5581 tgaatacgca taccgtgcgg tccggacgtc caaaagtggc accgatagct gccggaaggc
     5641 cgaagcccat agtacccagg ccaccggaag taacaatgct acgttccttg ctgtatttga
     5701 aataacgggc ggacatcatc tgattctggc cgacatcagt caccaatatc gcctcgttat
     5761 gggtagcctc actcacagca cgcaccacct cacccatgct tagcgctttt cctgccggat
     5821 gtaattccgg acggattacc ttttcctctt ccacttcctc gtattgccgg aaactgtcaa
     5881 tccattcctg atggttggcg ggttccagca attgggtaac ggcagccagt gtctctttgc
     5941 aatctcccag gacagcaaca tcggtcttta cattcttatc tatttcggca gggtcaatat
     6001 caaagtggat aatcttcgcc tgcttggcat atgtttccaa tttacccgtc acacggtcat
     6061 caaagcgcat gcctacggcg ataaggacat cacatttatt ggtattgata ttgggcccca
     6121 ggttaccgtg cataccaagc attcctttgt tcaacggatg gttcgtaggt aatgcggaaa
     6181 gtcccaataa agtgcatccg gcaggcattc cggctttctc aatgaaagca cgaagctctt
     6241 gctgggcttc tcccagctcc acgccttgtc caaccagcac caaaggccgt ttcgcaccat
     6301 ttattaattc agcagccttc cgtatggcct ccggctccat ttcgggaacg ggaagatagc
     6361 tacggacata gtccacctta gtaggcgcat attctgtttt ctccacttgg gcgtttttag
     6421 caaaatccag cacgaccggt cccggacgtc cgctctttgc cacatagaaa gcacgtgcca
     6481 ctgcccaggc cacatcttct gcacgacgaa tctggtaact ccatttcgtg ataggctgag
     6541 taatgcctac caagtccact tcctgaaatg catccgtacc caagaagttc gtccctacct
     6601 ggccggcaat gacaacgata ggcgtactgt caatcatggc atctgcaatg cccgtgatag
     6661 tattggtagc acccggtcca ctggtaacca gacaaacgcc aacctcgcct gatacacgtg
     6721 caaagccttg tgccgcatgg gttgctcctt gttcatgacg aaccaagatg tggttcaatt
     6781 ccttccgatg gtcgtataag gcatcgaata ccggcatgat gctccctccc ggataaccga
     6841 aaatagtctt tactccctga tgctccagag agcgcatcaa tgcttctgcg cctgttatta
     6901 gagcctcacc ccgaccctct ccttgggaga gggaggaaaa gttactcttt ttattattat
     6961 cagccatact ttatctattc attatattta aaagctcaat agtagcttga aaaatttgtt
     7021 tcattctctc ctcccctcgc tttcggaaag gggggctttt aatcaatcag cctcacagcc
     7081 cctttgtcag cggaactcac catactggca tatgctttca atgctttgga gacttcacgg
     7141 ttgcgggtta ccggagtcat aaggcgtgct gcaagctctt catccgtcaa cttcacattg
     7201 atagaacggt tcggtatatc aatttcgata atgtccccat ccttaatctt gccgatatta
     7261 ccaccggcag ccgcttcggg agaaacatgt ccgatactta gtccggaagt accgccacta
     7321 aaacgcccgt cggtaatcaa tgcacactcc ttacccagat ggcgggattt gatataagaa
     7381 gtaggataaa gcatctcttg catacccggt ccacctttcg gcccttcgtg agtgatgacg
     7441 acgacgtctc cactgaccac ctttccaccc agaataccgt cacaagccgc atcttgtgag
     7501 tcgaagactt tcgctggccc cgtaaatttc cagatactct cgtctacacc ggcagtcttg
     7561 acaacgcaac cgtcctgagc tatatttccc ttcaaaaccg ccagaccgcc atccttgctg
     7621 tatgcatgtt ccaaatcacg gatacaacca gtcgcacggt ccgtatcgag ttccttataa
     7681 gacgcatttt gtgagccgag taccagattg aactttccgg ctgccgcact ggagtatttc
     7741 ttgattgcct ctttacatac attagagctg gtaatactat accggtcgat tgcctctgcc
     7801 aacgtcattc catccacacg gcggacattc gtatcgacca atccgccctt ggcaagctca
     7861 tccatgatgg caatgatgcc accggcacgg ttaacgtctt gtacatgata cttttgggta
     7921 ttgggagcta ccttgcataa gcagggggtc ttgcgagaga gcatgtcaat gtcgtccatc
     7981 ttaaaatccg ctccggcttc gtgagccaca gccaacaaat gaagtactgt attagtggaa
     8041 ccgcccatcg caatatccag cgtcatggca ttcaaaaatg cctcgcgagt agcaatactg
     8101 cgcgggagta cactctcatc cccttcttca taatatctaa aggcattctc tacaatcaac
     8161 ctggctgcat cctcaaatag tttcttgcga ttttcgtgag tggctacaat cgtgccgtta
     8221 ccgggcagtg ccaatccaat cgcttcattc aggcaattca tggaattagc ggtaaacatg
     8281 cctgagcagc atccgcaagt ggggcaggca tgttgctcaa tctgtgccac ctctttatcg
     8341 cccacacttt catcagcaga tttaatcata gcatcaatca aatccaaatg ctgtccgttc
     8401 cattccccgg cttccatcgg accgcctgaa acaaacacag tcggtatatt cagcctcata
     8461 gccgccatca gcatccccgg agtaatcttg tcacagttac tgatgcaaac catagcatcc
     8521 gccttatggg catttaccat atactccaca ctatcggcaa tgatatctct tgaaggcagg
     8581 gaataaagca taccgtcgtg tcccatagcg ataccgtcgt caatggcaat cgtattgaac
     8641 tccgcagcaa aacaccccag tttttcaatc tcttccttta caaactggcc tatttcgtgc
     8701 aggtgtacat gcccggggac gaattgtgta aatgaattga ctatagcgat aatgggctta
     8761 cccatctgtt ccttcttcat accattcgcc gtccacaatg cacgggctcc cgccatgcgg
     8821 cgaccttgtg tgctgaacga gctgcgtaac tgatgcttca ttttcaaatc tccttttaat
     8881 gaaaaagcct ctcccactat agtgagaaag gcttaataaa ttatcttcta acgtacgaat
     8941 acatacataa cctttctcac gctcttgatg ccaccaccac gacgcgaata atatgcagga
     9001 ctgccaggtt aatagatgta tgtaaattca taacttaatt cttctttttt gtttcaaacg
     9061 tgctgcaaag gtaagggctt ttttataatc tccaaacaaa ttgaagaaaa aaataagata
     9121 aatatgaata atcgtaagaa aatatcgccc taaaatccta ttttatcact taacagttct
     9181 aaatagaacc attcagacag ccaatgtaaa tgtattgcca atcattgaaa ccatttaata
     9241 atctgaaaat taccaaaggc tctctacatc ccgaaacaaa taattcgtat ctttgtctct
     9301 tcaaatactc aaaaaaaagt atttactaat taaataaaga tagaaaatta atggaaacag
     9361 tagaaaacaa gtacatcacc gtagcatata agctgtactc aatcgaaaac ggagaaaaag
     9421 atttcgaaga agaagcaccc gtagagcatc cttttcagtt tatctcaggt ctgggaatga
     9481 cactcgaacc ctttgaagcc cagataaaag acttgcagat aggcgataaa ttcgacttta
     9541 ccattccggc atcagaagct tatggtgaat atgacgacga ccatgttatt gacctcccca
     9601 aagaaatctt catgatagaa ggagaattcg acagcgatcg tgtagtagaa ggtgccgtta
     9661 tccccttgat gacttctgaa ggtcaacgca tcaacggaag tgtggtagaa gtgaaggaag
     9721 atatcgtcgt aatggatatg aaccatccgc tcgcaggttg tgacttgaac ttcactggag
     9781 aagtagtgga aagccgcctg gctacaaacg aagaacttgc cgaagtcgcc cgtatgatgg
     9841 gtggcggttg cggcagctgc ggttgtggtg actgtggcga cggatgcggc gaccatgaat
     9901 gtggaggcgg atgctgccac tagaagaatt aaaaatgaag aattaaaaat gaaagaatca
     9961 aactacgcaa tataagtatg ctgcatgata attctttcat ttttaattct tcattttttt
    10021 aattatttac ttgtcattat ctccaatacc aatttatcag tttcattcat tcctttagaa
    10081 ccgatttttg tcagattacg gatactttga tccacatcct catcaataat accttctacg
    10141 gaagttacac aacggttttc catggccatg atggctgaaa gtactgcggt tgaaactccg
    10201 gtagtcactt tcaatgcaca actaggtttg gcaccatcac aaatcattcc ggtaagattg
    10261 gcaatcatgt tctgtacagc atatgccacc tgctcataag taccccccat tagccaagtt
    10321 ataccgcaac tggaacccgt agcagcaacc acacaaccgc ataaggcaga taagcgtccc
    10381 aaactctgct tgatatagat tactgtcaaa tggctcaaca tcaaggcacg aatcaattct
    10441 tcttctgatt tcccgttttc ttcggcataa atcaaaaccg gcaacgtagc ggatatacct
    10501 tgattaccgc ttcctgaatt actcatgacc ggaatcatag ctcctgccat acgggcatcg
    10561 caggcaccgg aagtataaga aagaatatgg gaaaaaacac tgtcccccat aaccttatg
//
