LOCUS       c00239_gnlPro..         3429 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPJJJFJF_239.
ACCESSION   c00239_gnlPro..
VERSION     c00239_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 04:40:33
            Original ID  :: gnl|Prokka|GPJJJFJF_239
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3429
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3429
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3429]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3429
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..3429
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3429
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             3..848
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_1"
                     /sec_met_domain="CT_Vparvula (E-value: 2.5e-124, bitscore:
                     403.9, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="ILKRLLSFLPSNNTEEPPHKLDTPLDLSADEGMSDLIPGDNRTPL
                     DVQPIISRLVDNGDFLEVHKDFAKNVVVGFGRICGVVVGIIANQPNVKAGCLDIDSSDK
                     AARFIRFCNAFNIPLVNLVDVPGFLPGKNQERGGIIRHGAKLIFAYSQATVPKVTLIMR
                     KAYGGAYIAMCCKDLGADAVFAWPGAEIAVMGAEGAVPVLYGRELKAVEDPAEKAKRQG
                     ELLEEYREAFYNPYVAAGMGQITEVINPEETRAKIAFALRTLLNKKEVRPAKKHGNIPL
                     "
     CDS             869..1315
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_2"
                     /sec_met_domain="OAD_gamma (E-value: 1.1e-11, bitscore:
                     33.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTTLAFAQGIANVMNNLNYQIVGIMVVMMCLGGLAVILTISGS
                     IAAAIQNRAKAKTAAPVAAPAAAPAAAGKPGMTPEMLAILSAAVDSAMTELTPEMVAVI
                     SAAVDAGLDGMSHRIVEIKQSPGSGYAAAGRAEIFASHRIRPSR"
     CDS             1390..1791
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 59.8; E-value:
                     5.7e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_3"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.6e-20, bitscore:
                     59.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRITVDGKVFDVSVELLDQVSSTTAAPAPAPVAAPAPAASAP
                     VAAPAPAPAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGASVKAGDQILTLEAMKMNTII
                     YAPASGTLTAFCVNPGDTVQEGQALAKIG"
     CDS             1909..2319
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_4"
                     /sec_met_domain="OAD_beta (E-value: 2.8e-17, bitscore:
                     51.0, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIFSLSWQMVGMWGIAILLLYLGVAKQYEPLLMVPIAFGALIAN
                     IPDNGMLITQLNQQVISSNEQGEVTSTSLNNVGYLRVHVAPLQQTPAKVPANLTTPEAR
                     AQYLETMQQPMQVYPGTQLTVSKIKSVRESQE"
     CDS             2362..3429
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg239_5"
                     /sec_met_domain="OAD_beta (E-value: 3.3e-130, bitscore:
                     422.5, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VDPNLKDFQNVTEDNGNEPVFLLTNGEGTTVVRQQGVNYFDTSGN
                     RVPVDLKTQKLEPLVVSAAGKYVAVGQHTQELLVTSIHGGLYDWIGLGIKAEIFPPIIF
                     LGVGALTDFGPLLAAPRTLLLGAAAQVGVAATFFMALFMGFNPNEAASIGIIGGADGPT
                     SIFLTMKLAPHLLGAVAVAAYTYMSLVPLIQPPIMALLTTKKERLIRMKSLRTVSKSEK
                     LFFAVLVTIVTILLIPDASPLIGMLMLGNFLRECKVTERLVQASQNEIINIVTIFLGTS
                     VGLTMQGDRFLQAETLLIILLGIVAFGVATAGGVIAAKLMNLIWRKNPVNPLIGSAGVS
                     AVPMAARVSHNVGQRS"
ORIGIN
        1 acatcctgaa gaggctgctt tccttccttc cttccaacaa cacggaagaa ccgccccaca
       61 aactggatac cccgcttgac ctgagcgcag acgaaggcat gagcgacctg attcccggcg
      121 acaaccgcac gccgctggac gtccagccca tcatcagccg cctggtggac aacggggact
      181 tcctggaagt gcataaggac ttcgccaaaa atgtcgtcgt cggcttcggc cgcatctgcg
      241 gcgtagtagt cggcatcatc gccaaccagc ccaacgtgaa agccggctgc ctggatatcg
      301 actcctccga caaggccgcg cgcttcatcc gcttctgcaa cgcgttcaat attccgttgg
      361 tgaacctggt ggacgtgccc ggcttcctgc ccggcaagaa tcaggaacgg ggcggcatta
      421 tccgccacgg cgccaaactc atcttcgcct attcccaggc cacggtgccc aaagtcaccc
      481 tgatcatgcg gaaagcctac ggcggcgcct acatcgccat gtgctgcaag gacctgggcg
      541 ctgacgccgt cttcgcctgg cccggcgcgg aaatcgccgt catgggcgcg gaaggcgccg
      601 ttccggtgct ctacggccgt gaattgaagg ctgtggaaga cccggcggaa aaagccaaac
      661 gccagggaga actccttgaa gaataccggg aagccttcta caacccgtat gtggcggccg
      721 gcatggggca gatcacggaa gtcatcaatc cggaagaaac ccgcgccaaa atcgccttcg
      781 ccctgcgcac cctgctgaac aagaaggaag tgcgcccggc caagaaacac ggcaacattc
      841 cgctctaaca tccatctcaa cggatcatat gttactcaca acactcgcct ttgcacaggg
      901 catcgccaac gtcatgaaca atctgaacta tcagattgtc ggcattatgg tggtcatgat
      961 gtgcctgggt ggcctggccg tcattctgac catcagcggc tccatcgccg ccgccattca
     1021 gaacagggct aaagccaaaa ccgccgctcc cgtggccgcg cctgccgccg cccccgctgc
     1081 ggcgggcaaa ccgggcatga cgccggaaat gctcgccatc ctctccgcag cggtggactc
     1141 cgccatgacg gagctcacgc cggaaatggt ggccgtcatc tccgccgccg tggacgcggg
     1201 cctggacggc atgagccacc gcattgtgga aatcaagcaa tccccgggct ccggctatgc
     1261 ggccgcaggc agggcggaaa tcttcgcctc ccaccgcatt cggccttccc gttgaactac
     1321 agcattattc acccttaccc ccgccccggc gggaaccatt taacttaata ctccatacca
     1381 tacattatca tgaagaaact tcgcatcacc gtagacggca aggtatttga cgtatccgta
     1441 gaactcctgg accaggtatc ctccactacc gcagccccgg cccccgcacc tgtggccgct
     1501 cccgctcctg ccgcatccgc acccgtggcc gccccggctc cggctcccgc acctgcgccc
     1561 gctccggccg ccgccggcgc cggagacgtg cccagcccgc ttgccggcaa ggttgtttcc
     1621 ctggacgtgg ccgctggcgc ctccgtgaag gccggcgacc agattctgac gctggaagcc
     1681 atgaagatga ataccatcat ctacgctccc gcctccggca cgctcaccgc tttctgcgta
     1741 aacccgggtg atacggttca ggaaggacag gctctggcca aaattggtta atcccggcgg
     1801 caaccgcccg gaacctccaa cagttcctgg ctccgactca gataacaaac cgctacaata
     1861 acattccgta tgagtctttt tgattcatta atcacctttt tacaggggat gggcatcttc
     1921 tccctatcat ggcaaatggt agggatgtgg ggcattgcca tcctgctcct gtatctgggt
     1981 gtagccaagc aatacgaacc tctcctgatg gttcccattg ctttcggcgc cctcatcgcc
     2041 aacattccgg acaacggaat gctcatcacc cagctgaacc agcaggtcat ctcctccaat
     2101 gaacaggggg aagtaacctc cacgtccctg aacaacgtgg gctacctgcg cgttcatgtg
     2161 gctcctctgc agcagacgcc cgccaaggtg ccggccaatc tgaccacgcc ggaagcccgc
     2221 gcccagtatc tggaaaccat gcagcagccc atgcaggttt atcccggcac ccagctgacc
     2281 gtttccaaaa tcaagtccgt gcgggaatcc caggaataag ccaaagctga cgccgcccgc
     2341 ctgggagacg acagtctgac ggtggatccc aacctgaagg acttccagaa cgtgacggag
     2401 gacaacggca atgagccggt cttcctgctc acgaacggag aaggaaccac cgtcgtccgc
     2461 cagcagggcg tcaattactt tgacaccagc ggcaaccgtg ttcccgtgga cctgaaaacg
     2521 cagaagctgg aacccctggt ggtttccgcc gcaggcaaat acgtggccgt aggccaacat
     2581 acccaggaac tgctggtcac ctccatccac gggggcctgt atgactggat cgggctgggc
     2641 atcaaggctg aaattttccc gcccatcatc ttcctgggcg taggagccct gacggacttc
     2701 ggcccgctgc tcgccgcacc gcgcaccctg cttctgggcg cggcggccca ggtgggcgta
     2761 gccgccacgt tcttcatggc cctgttcatg ggcttcaacc cgaatgaagc cgcctccatc
     2821 ggcatcatcg gcggagctga cggccccact tccatcttcc tgacgatgaa gctggctccg
     2881 cacctgctgg gcgccgtggc cgtggccgca tacacgtaca tgtccctggt tccgctgata
     2941 cagccgccca tcatggcgtt gctgacgacc aagaaggagc gcctcatccg catgaaatcc
     3001 ctgcggacgg tcagcaagag cgaaaaactg ttcttcgccg tgctggtaac cattgtcacc
     3061 attctgctga ttccggacgc atccccgctc atcggcatgc tgatgctcgg caacttcctg
     3121 cgcgaatgca aggtgacgga acgcctggtt caggcctccc agaatgaaat catcaacatc
     3181 gtcaccatct tcctgggaac ctccgtgggt ctcacgatgc agggagaccg cttcctgcag
     3241 gcggaaacgc tgctgatcat tctgctgggc attgtcgcct tcggcgtagc cactgcgggc
     3301 ggcgtcatcg ccgccaagct catgaacctc atctggcgca agaatccggt caaccccctc
     3361 atcgggtccg caggcgtctc cgccgtcccg atggcagccc gcgtctccca caatgtgggc
     3421 cagagatcg
//
