LOCUS       c00137_gnlPro..        13075 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POAAMADB_137.
ACCESSION   c00137_gnlPro..
VERSION     c00137_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:52:43
            Original ID  :: gnl|Prokka|POAAMADB_137
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13075
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1098
                     /locus_tag="ctg137_1"
                     /transl_table=11
                     /translation="DWSDRLIGIKGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYF
                     SGHSLVDFANEFQKRGGKVLLIDQVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKE
                     ENLELRDIAKSYNLRGFSFREFLNLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDY
                     FQDYLHHGFYPFFLEKRNFSENLLKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVD
                     GPKAPNVSQLASDVQTSRATVMNYIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLM
                     YSIYPVKVEEQDVLDTFFVNTLWKDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPD
                     VTYALQKAEIGRGNQIPLWMFGFLY"
     protocluster    1..13075
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1131:4689](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1132..4689
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13075
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13075
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1132..4689
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg137_2"
                     /sec_met_domain="PFOR_II (E-value: 4.1e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 5.8e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 6.4e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.1e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 3.8e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 9.8e-26, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             4814..5002
                     /locus_tag="ctg137_3"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(5013..5873)
                     /locus_tag="ctg137_4"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(5901..6731)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg137_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.3e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(6728..7954)
                     /locus_tag="ctg137_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIESV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             8428..9714
                     /locus_tag="ctg137_7"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQPFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(9677..10009)
                     /locus_tag="ctg137_8"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGVPQ
                     CSRMVGRALKEVPDELSIPCHRVVNTAGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(10037..12790)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 64.3; E-value: 4.2e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg137_9"
                     /sec_met_domain="Peripla_BP_1 (E-value: 6.1e-21, bitscore:
                     64.3, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTMRYLKWMLVLFGLIGMTACRQDTPHFRIGVAQCSDDSWRHKM
                     NDEILREAMFYNGVSVEIRSAGDDNSKQAEDVHYFMDEGVDLLIISANEAAPMTPIVEE
                     AYQKGIPVILVDRKILSDKYTAYIGADNYEIGRSVGNYIASSLKGKGNIVELTGLSGST
                     PAMERHQGFMAAISKFPDIKLIDKADAAWERGPAEIEMDSMLRRHPKIDAVYAHNDRIA
                     PGAYQAAKMAGREKEMIFVGIDALPGKGNGLELVLDSVLDATFIYPTNGDKVLQLAMDI
                     LEKKPYPKETVMNTAVVDRTNAHVMQLQTTHISELDKKIETLNGRIGGYLSQVATQQVV
                     LYGSLIILLLVAGLLLVVYKSLRSKNRLNKELFKQKQQLEEQRDKLEEQRDQLIQLSHQ
                     LEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADKTLSGDQHRMLMLIQRNVNILLR
                     LVNQILDFRKYENGKMEYTPVTVDVLSSFEGWNESFQAAARKKHIHFSFDSMPDTDYHT
                     LADMEKLERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTGSMISAEHI
                     RNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVELPVQSCEAV
                     AAKPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVHTLLHTDYT
                     VIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSL
                     DEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDK
                     DFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKA
                     ASLLASSDMTVAEIGYEVGFSSPSYFAKCYKEQFGESPTDFLKRKG"
ORIGIN
        1 gactggagtg accgtctgat tggtatcaaa gggacacgtg gcgtaggaaa aaccactttc
       61 ctcctgcagt acgccaaaga gaaattcggc accgatcgtt cctgtctgtt catcaatatg
      121 aacaactttt atttctccgg tcacagcctt gttgacttcg ccaacgagtt tcagaaacgt
      181 ggcggaaaag tactgctgat cgaccaggtg ttcaaacatc ccgaatggag caaagagcta
      241 cgaatgtgct atgaccgttt ccccagcctg aagattgtct tcaccggttc ttccgtcatg
      301 cgactcaaag aggaaaacct cgaattgcgt gacattgcga aaagttataa cctgcgcgga
      361 ttctctttcc gtgaatttct gaacttgcag acaggaatga aattccgggc atacagcctc
      421 gaagaaatcc tcagtacaca tgaacagata gccaaaggag tactttccaa agtacgaccg
      481 ctggattatt ttcaggatta cctgcatcat ggtttctacc ctttcttcct tgaaaaacga
      541 aatttctcgg agaatctgct gaaaacaatg aacatgatgg tagaagtgga tatcctgctg
      601 atcaaacaaa ttgagctgaa atatctttca aagataaaaa aattactata tttgttggct
      661 gtggacggac cgaaagctcc gaacgtgagc caactggcaa gtgacgtaca gacatcccgc
      721 gctacggtaa tgaactatat caagtatctg gcagacgcgc gtctgattaa tctggtttac
      781 ccgaaaggag aagaattccc aaagaaaccg tcaaagatta tgatgcacaa ctctaacctg
      841 atgtactcca tttatccggt gaaagtggaa gaacaggatg tactcgacac gttcttcgtt
      901 aacactttat ggaaagacca taaggtacat aaaggagata aaaacgtctc tttcatggta
      961 gacgaagtga tgccgttcaa aatttgtgcg gaaggtacaa aaataaagaa taacccggac
     1021 gtgacgtatg cgttgcaaaa ggctgagata ggccgcggca accaaatacc tctctggatg
     1081 ttcggattct tatactaaaa agatttattt acttaaatat ttaatttagt tatgactaaa
     1141 cagaagaaat tcatcacatg tgatggtaac caagctgcag cacatatctc gtatatgttc
     1201 tctgaagtag cagctatcta ccccatcact ccttcttcga ctatggctga gtacgtagac
     1261 gaatgggctg ccgcaggacg taagaacatc ttcggcgaaa cagtattggt acaggaaatg
     1321 caatctgaag gtggtgctgc cggtgcagtt cacggttctc ttcaggctgg tgcattgact
     1381 actacttaca ctgcttctca gggtcttctt ttgatgatcc ctaacatgta caagattgcc
     1441 ggtgaattct tgccttgtgt attccacgtt tctgctcgta cactggcttc tcacgcattg
     1501 tgtatcttcg gtgaccatca ggacgtaatg tcagctcgtc aaaccggctt cgctatgttg
     1561 gcagaaggtt ctgtacagga agttatggat ttggcaggtg ttgctcatct ggctactatc
     1621 aaatcacgcg ttccgttcat gaacttcttc gatggtttcc gtacttctca cgaaatccag
     1681 aagatcgaaa tgttggaaaa cgacgacctc gctccgctga tcgaccagga agctttggct
     1741 gaattccgtg cccgtgcact gaatccgatg aagccggttg cccgtggtat ggctgaaaac
     1801 cccgaccact tcttccaaca tcgtgaatca tgcaataact actatgaagc agttcctgct
     1861 atcgtagaag aatacatgaa cgaaatttcc aagatcacag gccgcaaata cggtttgttc
     1921 gattactacg gtgcagaaga tgcagaacgc gtaattatcg caatgggttc tgtaactgaa
     1981 gctgcccgcg aagctatcga ccacttggta gcaaacggcg aaaaagtagg tatggttgcc
     2041 gtacacttgt atcgtccgtt ctctgctaaa cacttcctgg ctgctgtacc caagactgca
     2101 aagagcatcg cagtgcttga ccgtacaaaa gaaccgggtg ctaacggcga acctctttac
     2161 cttgacgtta aagactgctt ctatggcgca gaaaatgctc ctgttatcgt tggcggtcgc
     2221 tacggtctgg gttcaaaaga taccactccg gcacagatca tctctgtatt cgaaaacttg
     2281 gctatgccaa tgccgaagaa ccacttcact atcggtatcg tagacgacgt tacgttcact
     2341 tctcttcctc agaaagaaga aatcgctctg ggcggtgaag gtatgttcga agctaaattc
     2401 tacggtctgg gtgctgacgg tacagtaggt gccaacaaga actctgttaa gattatcggt
     2461 gacaacaccg acaaacactg tcaggcttac ttctcttacg actccaagaa gtcgggtggt
     2521 ttcacttgtt ctcacttgcg tttcggtgat actccgatcc gttctactta cttggtaaat
     2581 actccgaact tcgttgcttg tcacgttcag gcttacctgc acatgtacga cgtaacacgt
     2641 ggtttgcgta agaacggttc tttcttgctg aacaccatct gggaaggcga agaactggct
     2701 aagaacctgc ctaacaaggt gaagaaatac tttgcacaga acaacatctc tgtatactat
     2761 atcaacgcaa ctcagattgc aatggaaatt ggtttgggca accgtaccaa tacaatcctt
     2821 cagtctgcat tcttccgtat cacaggcgta atccctgtag atcaagctgt tgaacagatg
     2881 aagaaattca tcgttaagtc ttacggcaag aagggtgaag acgttgttaa caagaactac
     2941 gctgctgtag accgcggtgg tgaatacaag actctgactg tcgatcctgc ttgggctaac
     3001 ctgccggatg atgcaaaagc agaaaacaat gatcctgctt tcatcaacga agtagttcgt
     3061 ccgatcaatg cacaggacgg tgacttgctg ccggtatctg cattcaaggg tatcgaagac
     3121 ggtacttggt atcaaggtac ttccaaatac gaaaaacgtg gtgtagctgc attcgttccc
     3181 gaatggaatg ctgaaaactg tattcagtgt aacaagtgtg cttacgtttg tcctcacgct
     3241 tctatccgtc cgttcgtact cgatgctgaa gagcagaagg gtgctaagtt cgagcaactg
     3301 aaagctgtag gtaaagcatt cgatggtatg acattccgta ttcaggtaga cgttctcgac
     3361 tgtctgggtt gcggtaactg tgccgacatc tgtccgggta atccgaagaa gggtggtaag
     3421 gcattgacca tgaaacacct tgaaagccag ttggccgaag ctgataactg gacttactgc
     3481 gctgaaaacg tgaagagcaa acaacacctg gtagacatca aggctaacgt gaagaactct
     3541 cagttcgcaa ctccgttgtt tgagttctca ggcgcttgct ccggttgtgg tgaaactccg
     3601 tacgtgaaac tgatttctca gttgttcggt gaccgtgaaa tggttgctaa cgctacagga
     3661 tgttcttcta tctactccgg ttcagttcct tctactccgt acactatgaa cgaaaagggt
     3721 cacggtcctg catgggctaa ctccttgttc gaagacttct gtgaatttgg tctgggtatg
     3781 gaactggcta acgaaaagat gcgtgcccgt ctggtgaaag taatgaacga agctatcgct
     3841 tctgattgct gcccggctga atacaaagaa gtatttgctg aatggatcaa caatatgctg
     3901 gatgcagaaa agactaagga actggccgaa aagatcattc cgatggtaga agctgctaaa
     3961 gataaatgca accactgcaa gcaaatcgct gatctgcaac aatatcttgt taaacgcagc
     4021 caatggatca tcggtggtga cggtgcttct tatgatatcg gttacggtgg tcttgaccat
     4081 gtaatcgctt ccggtaagga cgttaacatc cttgtattgg atactgaggt ttactctaac
     4141 acaggtggtc agtcttctaa agctactccg gtaggcgcta tcgctaagtt tgctgctgca
     4201 ggtaagcgtg tacgtaagaa agacctcggt ctgatggcta ctacttacgg ttatgtatat
     4261 gttgctcaga ttgctatggg tgctgaccag gctcagactc tgaaagctat ccgtgaagct
     4321 gaagcatatc cgggaccatc actgatcatc gcttacgctc catgtatcaa ccacggtctg
     4381 aaagccggta tgggtaagag ccaggaagaa gaagaaaagg ctgttaagtg cggttactgg
     4441 cacttgtggc gttacaaccc tgctttggaa gaagaaggca agaatccgtt ccaactggat
     4501 agcaaagaac ctaactggga agacttccaa ggtttcttga agggtgaagt tcgttacgct
     4561 tctgtaatga aacaatatcc tgctgaagct gaagaactgt ttaaagctgc tgaagaaaac
     4621 gctaaatggc gttacaacag ctacaaacgt cttgccagag aaaactgggg agctgataca
     4681 gctgaataat aagtagaaat actttgtaca taataaaagg caggaatcct ggaaacagat
     4741 tcctgccttt tttgtttata tcttagaagt aacgattact tctcacgaag atattcatta
     4801 aaactctaaa gatatgatcg gatttgttat ttggattatc ggtttgatac tgactttcag
     4861 agctgccata gagatttgga atataaatgc ggctgtagag aaaagactta tagcgattgt
     4921 attaatcgtt cttaccagct ggctgggact acttttctac tacttctatg gtaaagaaag
     4981 aatggcggga tggttgaagt agtgtttgca tatcaatctt tctcaggaat ccaactgttc
     5041 accagttcct gatgttcttc catccattga cgggcagcct gtctttccgt tgtctgcgcc
     5101 tcttccagag cagtcattaa ggagctgatt tccgcatctg tcagacgaat gttgcccaaa
     5161 agttcggcag caaaagggtc tttctcgcta aaacctttcc atgctatggt atgaatggat
     5221 tccgtatttc catatatcag cttcgggtcc tgaagaactt tcagcttgaa acggtcgaac
     5281 atccagtgag gcgtccatcc cgtcacgaca atccagtctt tcttatcaat cgctttcttt
     5341 agggaagcag tcatggcagg tccgctcgaa gtcatcagtt tataatccaa tccatagtct
     5401 ttgatggcct gatcggtagc tttcataata ccggctccgg catcaatacc gacaatctga
     5461 ccggagaaac gttccttttc cgcgttcagt tcttcgattg agttgatcgt aacgtaatcc
     5521 ggaaccacca gcccgatacg ggcaccatca taaatatccc cgataacttc gagtttatcc
     5581 ccgtattgtt tcatataatc ttccatagtg acaggcatcc agacatccat aaatacgtct
     5641 gctttcttac gggagataga ggtaaatata ggtgcaaggt cggcattcag caactttaca
     5701 tcgtacccct gatcttcaaa aatcgctttg gcaaggtttg tcattgcaat accttccgac
     5761 cagttggcat aagcgatact tatcttctta ctctttccgt tgtctccgca ggaaacgaag
     5821 gttaagagta tgccggcaat aaacattgcc gcaatcattt ttatcttatt cattgattat
     5881 tcctttcttt ggtgtgattc ttatttcttt ttactttttc tgttatctgc cataccctga
     5941 gtgatgcggt ccagcacgat cgccaatatc acgactgcga taccgccttc aaatccgagt
     6001 ccgattttca tttgggtgat acctttcagc acgatttctc ccaatcctcc ggcagaaatc
     6061 atggcagcaa tcactaccat cgaaagtgac atcatgatcg tctggttgat tcccgtcaga
     6121 atagtaggca acgccaaagg caattgcacc ttataaagaa gctgccaggg agtagctcca
     6181 aaagagcggg aggcttctac tacgttttta ggaacctgac gaatgcccag accggtcaga
     6241 cgaaccacag gaggcattgc aaagatgatg gtggcaaaag ctcccggcac agttcccaat
     6301 ccgaagaata gaacggcagg aatcagatag acaaaggcag gcattgtctg cataaagtcg
     6361 aggacagggc gcattatctt gttacaacga tcactgttgg cagtccagat tcccaacgga
     6421 acgcctaaaa gcaatgccag acaagtggaa gaaagtacca atgccaatgt ctgcatcgtt
     6481 tcttcccaaa agcccatgcc gtaaataagc aataaaccca agagggtaaa tacggctgtc
     6541 cccttacccg acttaaacca ggcgagcgca gccagcactg caattgtgat ataaaaaggt
     6601 attccaaaca gtacgtgctg aaaaccgtct atgaatcctc cgatccccat gctgagagca
     6661 tcaaaaaagg aagcaaaatg ttctgtgagc caattaatgg cagtctctat atattgtccg
     6721 atatttatca taattctatt gcgttttgaa tgatttcatt aatttcttct ttatcttttc
     6781 ccgttacttc gatgatcaat gaggaaagtg gcactacgcc ttcaaactcc cgattctcat
     6841 ttacgaccca gattggcgag ttcgtttttg tcatcaacgg aagaatatct tccagcaccg
     6901 tatcacccag cactgaatga acttcatgcc ttactacgga ctcgatggag cggatttgct
     6961 cttttcgtag tttcagcaag tcattcaacc gcacctctcc tactaacaga ttattggaat
     7021 cgactaccgg aagaacggtc agattccgtt cgcgcatctt acggatcagc acctccgggc
     7081 cttctttctt caaacgtgcc actatgggtt tatctaccat aacagaggaa gctgttataa
     7141 tcttgcttcg atctacattc tccacaaatc gttctacata agcgttggca ggttcggtca
     7201 ggatttcttc cgatgtaccg atttgtacaa tttctccatc cttcatgata gcaatccggt
     7261 cacccaattt aatcgcttca ctcaggtcgt gagtaataaa gacaatcgtt tttttcatct
     7321 tcgactgcaa agtcagcagt tcatcctgca tctgcacacg gatcaaagga tcgagtgccg
     7381 agaaggcctc atccatcaac aggacttcgg gattattggc caaagcccgc gccagcccga
     7441 cacgctgctg catcccaccc gacagttcac ttaccatctg attctcgtag cctttcagcc
     7501 ccaccagttg catgctttcc atcgctttct gctcccgttc tccctttttt actccctgta
     7561 gttcgagccc gaaagctata ttatgcaaga cagaacggtg aggaagcaga ccgaagttct
     7621 gaaagaccat agccagttct ttccggcgaa tctgcaacag ttccttatcc gacactttgg
     7681 ctatgtctgt tccattgata atcacttctc cggaagtagg gcgtatcaaa cggttgatgc
     7741 agcggagtaa agtggacttt ccactaccgg acagccccat aatgacgaat atttcgcctt
     7801 cattaatgga aagattcgca tctttcaccg caactgtaca tccggtcgct ttcaatattt
     7861 cactttttgt tttaccttct ttcaacatct tcaaagcctt ctgcttctca ttgccaaaaa
     7921 ccagatagag atctttaatt tctattttac tcatacaata aaatggttta ggttattaaa
     7981 ataatataca cagcaagaca agaacaaacg ataacaggaa tctttcttta tatcgtataa
     8041 agttctgatt taaatacggg acaaataaca atgaatcccg aaataattaa tagaatgatt
     8101 attgacagac tgagtaatta aaaaaggaat agaatttgat aagataatcc tttcaacgaa
     8161 tagcaaaaaa atagcatttt tatgtataaa aacagcctgt tccagtatct tgctggcaca
     8221 aagatacaaa aaacagatta aacatgcaaa ttatattcaa aatccggggc atacagaggg
     8281 ctttatttgt aatgatatgg aaagttttcg ggtaatattc ccctatcact cagcaaaata
     8341 gaacaaaccg gcagataaat ataaaataag tttgaatatt tcacctaaac accgtatatt
     8401 tggcgtcaat aactaaacta gatttatatg ttcaacaggg ctattacaat tttcctgggg
     8461 aaggataatt gtcattacac aacaaaagaa aaacaaacag gtactgccac actagacgac
     8521 aaaagccaag tacagttcct tagtaaaaag aaccccaaaa tgccgttttt ctatagtcgg
     8581 cggaatctct acatgatagg tttcctgctc gcttttatag tgactctgct cgaatttatg
     8641 cgaggacggc atcaaaactt tatggtcttc tcagacgcta ctcaattctt ctggcaaggc
     8701 atcagcccat acacaaccga atttgtagaa gctcacggac gctacttcct ttattctcct
     8761 gttttcacgg tattgttcgc tccgtttgcg tatctgcctg catggctggg acctttcgcg
     8821 tggaatctat tcaattattc attgtttttt gtagcgatct tcacgctgcc ccaaccattc
     8881 acccagcagc agaaatgccg tatgttcctc tttctgttac tgattttagg acaaagttta
     8941 ctttcatttc agtataacat aacggtagcc tatttattct tattcgccta tacgttattg
     9001 gaaaaagacc gtggatttct ggctgttctg ttaatcatga tttcgggatg taccaaagta
     9061 tatggaattt tcgaactggc attgttgctg tgttatcctc acgtatggcg taactttggc
     9121 tatgccgttg caatgggcat tgtattgctt gcgttaccgt taatcaaaat agctcctgca
     9181 gatttgctcc cctattatga agaatggtgc catagtcttg ctgttcatca atccaccgga
     9241 gcttatgatt catttttcta tgcccgcccc attgcagcat ggacattgcc acacttccgt
     9301 gcacttcaga taggaatgct cggtctgctg actctgctct ttttggggaa tttccgcaaa
     9361 tggtcgtctt ttgccttccg tgcccaagct ttgggcattc tcatgggctg ggtagtatta
     9421 ctgagtgact ccgccgagaa gcatacctat attatcgcat tggcaggttt catgctctgg
     9481 tattggagca gaccaacacg taccgcaaca gacaagattc tattttggtg ctgttttgtg
     9541 ctgttatgta tcgttcctat cgacatattc gtccctgtac ccatcagaga tttcattacc
     9601 aggaccttat ggcttcatgt atgggttttc tttattgtat ggatacggat gatatggctt
     9661 accttccttg catccttcat tcatccacgt gccacaaatg ttctttcaga ttaacgcatc
     9721 cgttagcttt gaaagaaact tcttctgcca gcaagagttg tttttgttcc acccaaccgg
     9781 gcaccagcct tccggcggta tttacaactc tatggcaggg aatggataat tcatccggca
     9841 cttctttcaa tgcacgtccc accatccgcg agcattgggg tacccccaac aacaaagcaa
     9901 tacctccata ggtagatact tttcccacag gtatctggga tacgacttcg tacacttcct
     9961 tccgaaagga ttcggaaaag ctctctttat ctactttata atctttcata tatccctctt
    10021 tacgatatca atgaaatcat cctttccttt tcaggaaatc tgtcgggctc tctccaaact
    10081 gctctttata gcacttggcg aaataagaag gtgaactgaa accgacttca taaccaatct
    10141 ccgctacggt catgtccgaa gaagcaagca aagaagctgc cttcttcaaa cgggcgatac
    10201 ggagcaattc attcggagag tagttagtca atgatttaat cttgcgataa agctgcacac
    10261 ggcttagtcc catgtctttg cccaagtcct ccacattcaa accggagtct cccattttct
    10321 cttcaatcaa tgacttgaat ctttctacaa aatccttgtc catatcgcag acatcttctt
    10381 ttgccaatgt ctgcccgtca ccaaagaact gtttcagacg acggtgagaa tcaatcagat
    10441 tgcggacacg tgccagcaac agctgtgaac tgaacggctt tgaaatataa gaatccgcac
    10501 caccgtcata tccctgaata cgctgttcgt ccagtgaaca cgctgtcagc agaataaccg
    10561 gaatatgaca ggtctgtaac tcacttttca gccggcggca acattcaatg ccatcaatgc
    10621 ccggcatcat cacatcagaa atgatcaggt ccggaacata cttcatagcc ttacggattc
    10681 cttcggagcc gtctgccgct tcaatcaccg tatagtctgt atgcaacaac gtatggacat
    10741 acgaacggat atcctcatta tcatcaataa tcagtacgga cggtttggaa gagtcatatc
    10801 ctttttccag ttcttcctct tccgccaata gaacatctgt tgtacgggaa tccgcagaaa
    10861 caagggtggt atccggtttg gcagcaacag cctcacaaga ctgtacaggc agttcaacgg
    10921 taaagaccgt gccctgtttc tcatcgctct ctacggagat cataccaccg tgcatttcta
    10981 cgaaggcttt taccaatgcc agtccgattc ccgaaccggt atggtgcata tcgatcttat
    11041 agaaacggtc gaatacattg cgaatatgtt cggcagaaat catggaaccg gtatttgcca
    11101 ccgtgaaacg tatccatcgc ttgtcctctt tactaaggga agacagacgg acggctattt
    11161 tcccgttttc cggtgtaaac ttaaaggcat tggacagaag attgaaataa atacgttcca
    11221 gcttctccat gtctgccagt gtatgataat ccgtatccgg catactatca aaagaaaaat
    11281 ggatatgctt cttacgggct gccgcctgaa aagactcatt ccatccttcg aaagaagaaa
    11341 ggacatccac cgtaaccgga gtatattcca tcttgccgtt ttcatattta cggaaatcca
    11401 gaatctgatt gaccagacgc agaaggatat tcacatttcg ctgaatcagc atgagcatcc
    11461 ggtgctgatc tccactcaat gtcttgtccg ccaataaatg ttctaccggg tcggcaacca
    11521 atgtcaacgg agtacggaag tcgtgagaaa tattggtgaa aaagaccagc ttggcatggg
    11581 tagcttcttc cagttgatga gagagctgta tcaattggtc acgctgttct tccagtttgt
    11641 cacgctgctc ttccaattgc tgcttctgct taaaaagctc tttattcaag cgattcttag
    11701 agcggagtga tttataaacg accaataata aaccggctac caataaaagg ataatcagac
    11761 tgccgtataa aacaacctgt tgtgtagcta cctgagagag gtatccaccg atacgtccgt
    11821 tgagcgtttc aatcttttta tcgagttcgg agatgtgtgt agtctgcaac tgcatgacgt
    11881 gtgcgttggt acggtccaca acagcggtat tcatcactgt ttctttggga tagggtttct
    11941 tctccagaat gtccatagcc agttgcagta ccttatcgcc attggtcgga tagataaagg
    12001 tggcatccag cacactgtcc aaaaccagtt ccagtccgtt tcccttaccc ggcaaggcat
    12061 ctatgccgac aaaaatcatt tccttctccc gccctgccat ctttgctgcc tgataggcac
    12121 ccggagcgat acggtcatta tgggcataca cagcatcaat cttaggatgc ctccgaagca
    12181 tactatccat ttctatctct gccggaccac gttcccacgc agcatccgct ttatcaatca
    12241 gctttatatc cgggaattta ctgatggcag ccataaatcc ctgatgccgt tccattgcag
    12301 gagtcgaacc gctcaatcct gtcagttcta ctatatttcc cttccctttc agactggagg
    12361 caatatagtt tcctaccgaa cgaccgattt cataattatc ggctccgata taggcagtat
    12421 atttatccga aagaatcttc cggtctacaa gaataacggg gatgcctttc tgataagctt
    12481 cttctacaat cggagtcata ggagcagctt cgttagcgga aataatcagc agatcgactc
    12541 cttcgtccat aaaataatgg acatcttccg cctgcttact gttatcatct cctgccgaac
    12601 ggatttccac cgaaacgcca ttataaaaca ttgcttcccg aagaatctca tcattcatct
    12661 tatgtcgcca tgaatcatcg ctgcattgag ccaccccaat acgaaaatgg ggtgtatcct
    12721 gccggcaagc cgtcatcccg attaaaccaa acagcaccag catccacttc agatatctca
    12781 tcgtcttcat ccatctcatc atttcatagt tctttctgta atccaattaa gaacaaaaat
    12841 aagaaataat actgtaaagt tctctaactt cagctattta ttattctaaa aagaaggaaa
    12901 gcagtcctct ttcagaccat cggaaagtat taacaaaagt ataaagcgta aaacaaacac
    12961 ttaatcaatg ttataaaaca tagcgtttta cttggataat ttgcagattt cacagaagtc
    13021 cgtatctttg cactgtgttt ttcatagtat tagatttaag gttaacaaag gttgg
//
