LOCUS       c00038_gnlPro..        16182 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DLEEINDK_38.
ACCESSION   c00038_gnlPro..
VERSION     c00038_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:48:53
            Original ID  :: gnl|Prokka|DLEEINDK_38
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 105
            Orig. end    :: 16287
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16182
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[10105:13075]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12970
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16182
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16182
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(234..3125)
                     /locus_tag="ctg38_2"
                     /transl_table=11
                     /translation="MEKKSEGKTRKCLTLLGGRTSLLLCLSLMFQSSYAAGDSTVPEMG
                     NMEIHQIAQQSSTIKGVVKDQKGEPLIGVSIVVKGTTNGTASDFDGNFTLDVPDNSTLV
                     FSFIGFKPQEVRYTGQKTLNIVLAEDSETLDEVVVVGYGSQKKGEITSSVTSVKASDFN
                     KAPVVNPMQLVEGRVAGLTVSRGSTDPNGEVKVQMRGASSLKGSNEPLVIIDGMPGNMT
                     SLNAIAPEDIEAIDVLKDGSAAAIYGTRGNNGVIIVSTRRPQAGTTQVDYSGYIMHEAV
                     YKRPEILNGDEFVAYGKETNNANIRDFGGRDNHYDALLNKSNFTHVHNLTATGGNGKTN
                     YRASLNYKKNDGMIRNTSRETINGSIAVNHRAFDDKLQLSFNLANSFVKVDAVSDDVDK
                     VGDIPNYGILYQAIRINPTMPIYKEDGSFWETYSGYEDFNPVARIYQRTKKKEFKNLLA
                     NFKAQYEIIPGLTAAAFFAMEKNDALTNDYSMREEYSQHKDGTNGRAKKEYYQNTNRTT
                     EWTANYNTSINGVHNITGLLGYSYQDFEYEQFSAENKNFLTDVFGTNNLEAGGYLKDGK
                     AEMKSKKETSKLIAFFARANYNYDGKYMASASIRREGSTKFGANNKWAWFPSVSAGWMI
                     SREDFMESQEVFDVLKFRAGFGITGSLPTDPYMSLATYGTGAGAWNAYTGSWLTATYGP
                     NINPNPDLKWEKNESLNVGFDFGLLGGRLNGTIDWYSRTTRDLISSYNAQQPSLIYNTI
                     TTNVGTMRNRGIELALNAEVVKTKDFSYTANFTFSYENNKLTSLSNDVYKSSYEDQYDL
                     PSPGNPGKAYRLQEGQPIASFFGYVCDGINPDGTWNLRDIDGKEGLSDADRTFIGNGLP
                     KFKAGLQNTFTYKNFDFSFFLRGMFDYDVLNEGAIYFGTTVNIDQSGTNVYKDALKNKV
                     TEQPLFSSYYLEKGNFLKIDNVTLGYTFNFKNH"
     CDS             complement(3328..3738)
                     /locus_tag="ctg38_3"
                     /transl_table=11
                     /translation="MTNQRELKEYFYSPESAYQYTEGQLLHQEDKEFLDAVTAIIKENV
                     SKEGLGPELVADALNINTRILYRRFKKISTMTPSDFIKDYRLNYAAQLLVNTNMSVQEI
                     IYNVGISNKSYFYREFARKYNMTPKEYRTKEA"
     CDS             complement(3786..7370)
                     /locus_tag="ctg38_4"
                     /transl_table=11
                     /translation="MRFTRLILALTSFLILITQTDLFASTVLHKTSMVDLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVDTDNKLYRQHVDGKGKEFLFDLPEMTKQYGNIIKICTFQSNVYIVFRNGNILDL
                     SQPENTINMGIGIFCLMNDKRQEILWLGTDGQGIRMFYDKPDLFGSILLKDLPINIQNP
                     IRSLYTDDDQSLWLGTKGDGIVRIQAYDTYHNKKMIPQSAITHFTTADGLSSNRVYCFQ
                     KSEYHPCIWIGTEGPGLTYYSYKEKRIKTIPQREDTTPLRYVHSICEVDDSTLWLATTG
                     NGLQKVTLHIDKAVPTIGKVQTFPLKNGKNICKEIQSMVYDNDSTLFLGSRGGYGVIRF
                     NIFNQGYEFLQTNNLRNPAIGDVLSVCQTEDSTFYAGASSGLTRIKFRGGKMRLRQFDK
                     SDGIVNDMIHGIHEGNDSCIWLSTNKGLTKYNPRNNFFHNYHQPYFSVTEFSDDAYWKC
                     PYSERLFFGGINGLVWVNKQTEPEHTYQPELSFFELQMDKQILPLYKDISRNGVTVPAD
                     VQSLTIAFVAPDYINGENYEYSYQLVNYNSSWEKLQKTNKVTFMNLPYGEYLLKVRYRN
                     DVIDSSAKEYTLPIKVLPPIYLSSLAIFTYLFIGTVLLIIATYRIHHQILKKQKQIADK
                     IKEEQKEKLYESKLNFFTHITHELCTPLTLINGVENYIQAYAATSKDKTLEKYTSVLRE
                     NVEELNGLIQEILDFRKAEDAGFSHTHIRRVSVSSLLRTQFEWFYPLSEQHQIQFKIDA
                     PKELYWNTDSVYFKKILANLISNAFKYTEDGGTVRISLHEEENFLVLKVYNTGKGIEEA
                     DMQNIFDRYRILGTMDNDDNRQNTTRNGLGLFICHSLVQSLGGKIDIESEVGQYAEFTV
                     TLPFGIVEETSDNTIDEEIPVSLPSPNTDIQEPQISHTAQKETEDKPMILVIDDHKDIV
                     WLITETLSSEYQVQEAYNAEKALEFLKQYTPSLIITDIMMPNMDGLELISLIKEXXXXP
                     AISRLLSSLLKYQTKSKRQDLISERMPI"
     CDS             7527..9830
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MEQCEENSQENDDVIIEKEISKLIEEQRLFTESIYACLPVGIEIY
                     DAHGVLRSINDHALRMYGVDDRTSVVNIVNLYKSPFVDSELLARIQSGEDISLEFEYDF
                     DRVNKDAYYSSHNKDTMIYGVKVIPIWSRKKHLIGHILLANDMTSVKEVEFRTEESKKN
                     LEMAMKAANMASWVYDVNKKVFNPLYGLTVAKKNMPMEAVLDILHPQDRAPLIRLFSQL
                     IGNEIEQGQMTLRFYNEQEEMYRYYESRMRLSTEHRGKLQIIGTQMDITERLQMAKKAQ
                     DLIAKRDLAMKVSNIVHWDFDVNSQKFESYNDPINDYVSDRLLTVSEYMDVIYPEDRSV
                     FYDAMQSLIAGKNVTINFTCRIQTKYDETWQYCDFMGVPFDQDENGDIIRYTGFRQNIP
                     KIQQLNRELKERNYKIELSFKTVGMSYWDFDVKSLKFSAFNDPINDFYSEKTITPEDYL
                     NATHPDDVVFVRKYMEHMFRGIDKDFNVKYRSKTKWDDEWQTLLVTGIQVERDKEGHVT
                     RYTGITINNTKWEKMIQQLKELKEKAELSDRLKSAFLANMSHEIRTPLNAIVGFSELMV
                     TCDDPEEKKEYINIIQSNNELLLRLINDILDLSKIESGIIERRKENFNLAKVCNELFVT
                     IQAKMTNPNVELRLDGPNSECWVLLDRNRLKQVWMNFLTNAVKCTKSGYIKMGYGIERE
                     GLRIYVEDTGIGIPDDLHDKVFTRFEKLNEFSQGTGLGLTISRAIVEAAGGEVGFTSKL
                     GVGSTFWAWLPLRP"
     CDS             10001..12235
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_6"
                     /sec_met_domain="Gly_radical (E-value: 4.3e-46, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 2.9e-279, bitscore:
                     917.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGVYDVETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFMEY
                     LRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGAIA
                     ALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNVNV
                     FDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             12236..12970
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 66.9;
                     E-value: 7.6e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_7"
                     /sec_met_domain="Radical_SAM (E-value: 2e-33, bitscore:
                     105.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWTPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLSYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             13169..13747
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MKTPQEIAEMISKRFYPLPDADLDSLASIIESSKAAKGELLLDNG
                     QISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNIVICIASTFQREPTRLLIEALEPTV
                     YHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQEKADSWRFESARKRYLRFQQEYPE
                     AAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             13948..14514
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             14534..15577
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.2e-17, bitscore:
                     52.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESILKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDVA
                     SCSDKISMRVSDGEGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASSAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIIATGASWRKLNVPGEAEYIGRGFLS
                     SLRRSVL"
     CDS             15675..16082
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_11"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.6e-19, bitscore:
                     59.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDELKADQVLQEKAKSLPNVEIFVSSQTTEVVGNGDKVTGIRTKD
                     RKTGEERVIHLDGIFVQIGLAANSGVFKEIVETNRPGEIVIDAHCRTNVPGIYAAGDVS
                     TVPFKQIIISMGEGAKAALSAFEDRVRGVLD"
ORIGIN
        1 aaattagtgt ggcaattatc acatacagtc ttgtggctat tgtccaacat gatatgaatt
       61 tgaaacgctc aacctatgaa gtcttgcaga ttctcagcat atcattgact gacaaaaccc
      121 acttgtatga cctgttcgac aagactaatt tcaatgatgt caaagatcta aatgatcccc
      181 taattccggg gctatttgat taattgttta actcgtccca ttttaacggg acactaatga
      241 tttttgaagt tgaatgtata acctagtgtc acgttatcga tcttcaagaa gttccctttc
      301 tctagataat aagaagagaa caatggttgc tctgttacct tgttcttcaa ggcatcctta
      361 tatacgtttg tgccagactg atcgatattg acagtcgttc cgaaataaat agcaccctcg
      421 ttcaatacgt cataatcaaa cataccgcgc aggaagaagc tgaagtcaaa gttcttatag
      481 gtaaacgtgt tctgtaaacc agccttgaat ttcggcaaac cgttaccgat aaaggtacgg
      541 tcagcgtcag acagaccttc ctttccgtct atgtcgcgaa gattccaagt tccgtccggg
      601 ttgatgccat cgcatacata accgaagaat gatgcgatcg gctgtccttc ttgtaggcgg
      661 taagccttgc ccgggttacc cggagagggc aggtcatatt gatcctcgta agaagatttg
      721 tacacgtcgt tagacaaaga tgtcaattta ttattctcgt atgagaacgt gaaattagcc
      781 gtgtaagaga aatccttagt ctttacgacc tctgcgttta atgctaattc tatacctcta
      841 tttctcatcg tgcctacgtt ggtggtgatc gtgttgtaga tcaaagatgg ctgttgggca
      901 ttgtagctac tgatcaagtc gcgagtcgta cgactatacc aatcgatcgt accatttagg
      961 cgtccaccta gcaagccgaa gtcgaaacct acgttcaagg attcattctt ctcccatttc
     1021 aaatctggat tcgggttgat attcggaccg taagtggcgg ttagccatga accggtgtaa
     1081 gcgttccaag ctccagcgcc tgtaccgtag gtagcgagag acatatacgg atcggtaggc
     1141 aaactacccg tgataccgaa accggcacgg aatttcaata cgtcgaacac ttcttggctc
     1201 tccatgaagt cctcacgaga gatcatccag cctgcgctga cagaggggaa ccaagcccat
     1261 ttgttgttcg ctccgaactt cgtggaacct tcacggcgga tagaggcgct ggccatgtat
     1321 ttaccgtcgt aattatagtt ggcgcgggcg aagaaggcga tcagtttgct ggtctctttt
     1381 ttactcttca tctcggcctt accatctttt aggtaaccgc cggcttctag gttattggta
     1441 ccgaatacgt ccgtcaagaa gttcttgttc tcggcgctga attgctcgta ttcaaaatct
     1501 tggtaactgt atcccagcaa accggtaata ttgtgtacgc cgttgatgga agtattgtag
     1561 tttgctgtcc attcggtggt acggttggta ttctgataat attctttttt ggcgcgtccg
     1621 tttgtaccgt ctttatgttg gctatattcc tcacgcatac tataatcgtt agttaacgca
     1681 tcgttcttct ccatagcgaa gaaagcggcg gctgtcaaac cggggataat ctcatattga
     1741 gccttgaagt tcgccaataa attcttgaat tcctttttct tggtacgctg gtatatgcgg
     1801 gctaccgggt tgaaatcttc gtaaccgctg taagtttccc agaaggagcc gtcttcctta
     1861 taaataggca tcgtcgggtt gatacggatc gcctggtata atatgccgta attagggata
     1921 tctcctacct tatccacatc atcggaaact gcgtccactt tcacgaaaga gtttgctaga
     1981 ttgaaagaaa gctgtagttt atcatcaaac gcacggtggt tcacggcgat agagccattg
     2041 atcgtttcac ggctggtgtt acggatcata ccatcattct ttttgtaatt taaagaagcg
     2101 cgatagtttg tcttaccatt accacctgta gcggtcaagt tgtgtacatg ggtgaaatta
     2161 ctcttattca ataaagcgtc gtaatggtta tcccgtccac caaagtcgcg gatattggcg
     2221 ttgttagttt ctttgccata agcgacgaac tcgtctccat ttaagatttc cggtcgttta
     2281 taaaccgcct cgtgcatgat atatcctgag taatccactt gagtagttcc ggcttgcgga
     2341 cgtctcgtgg agacgatgat cacaccgtta ttaccccggg ttccgtagat agcggctgcg
     2401 gaaccgtctt tcaatacgtc gatcgcctcg atatcctcgg gtgcgatagc attcaaagaa
     2461 gtcatattac ccggcatacc gtcaataata acgagaggct cattgctacc tttcagagat
     2521 gaggcaccac gcatctgtac ttttacctcg ccattagggt cggtgctacc acgtgataca
     2581 gtcagaccag ctacacgtcc ttccaccaat tgcatcgggt tcactaccgg tgccttgtta
     2641 aagtcggatg ctttcacgct ggtaacggat gaggtgatct cacctttctt ttgggaaccg
     2701 tagccaacga ctactacctc gtctagtgtc tcagagtctt cagctaagac tatgttcaat
     2761 gttttttgcc cggtataacg aacttcttgg ggtttgaagc cgatgaagga aaataccaat
     2821 gtgctgttat ccggcacatc caaggtgaaa tttccgtcaa agtccgaagc tgttccgttc
     2881 gtggttcctt tcacaacaat actaacgcca atcagaggtt cacccttttg gtcttttact
     2941 acacctttaa tggttgaact ttgctgtgcg atctgatgaa tctccatgtt tcccatttca
     3001 ggaacagtag aatctccggc cgcataagag gactgaaaca ttaaagataa acaaagtaac
     3061 aaagaggttc gtccacctaa taaagtcagg catttcctcg tcttaccttc actctttttt
     3121 tccataaaaa cattaaatta aaagttaata atgtgcttcc cgaaggaaga atacacacaa
     3181 gcggtttgct ttgctattcg acagcaatat taataggtct taacgaattg aagagtgctt
     3241 tgaaatgcca aagaagtgtc atgaaatgca tatagcagat tatgatactt ttttggtaga
     3301 ttatgacact atttaggaat caatgattta tgcctctttt gtgcggtatt ccttaggtgt
     3361 catgttatat ttacgggcaa attccctata gaagtatgat ttgttagaaa ttcctacatt
     3421 ataaataatt tcctgaacgc tcatgttggt attcacgagt aattgcgctg catagtttaa
     3481 cctataatcc tttataaaat cactcggcgt catagtagat attttcttga aacgacgata
     3541 taatatgcga gtgtttatat tcaatgcgtc cgctaccagc tcgggaccga gtccttcctt
     3601 gctgacattt tctttgatga tagcggttac ggcgtcaagg aattccttgt cttcttgatg
     3661 taataattgc ccttccgtat attgataagc actttccgga gaatagaaat actcttttaa
     3721 ttctctttgg ttagtcatca atcgattcac gacggatagg agaactgttg gcgagaaagg
     3781 cttggttaga taggcatccg ctccgatatt aagtcctgcc gcttgctctt ggtctgatat
     3841 tttagcagag atgataataa gcgggatatg gcgggtannn nnnnnnnttc tttgataagc
     3901 gagatcaatt ccaatccgtc catattaggc atcatgatat cggtgatgat aagggacgga
     3961 gtgtattgtt tgaggaattc cagagccttt tccgcattat aagcttcttg aacctgatat
     4021 tcggaagaga gggtttccgt gattaaccag acgatgtctt tatgatcgtc gataacgagt
     4081 atcatcggtt tatcttccgt ctctttttgt gccgtatgtg agatttgcgg ctcttgtata
     4141 tccgtgtttg gggaaggaag cgatacggga atctcttcgt ctatcgtgtt gtctgaggtc
     4201 tcctctacga tgccaaaagg taaggtaact gtaaattcag catattggcc gacctcactc
     4261 tctatgtcga ttttaccacc taaggattgt acgaggctgt gacagataaa taagccgagg
     4321 ccattccgtg tcgtattttg cctgttatca tcgttgtcca tcgtgccaag gatacgatat
     4381 cggtcgaaaa tattttgcat gtctgcctcc tcgattcctt tgccggtgtt gtaaacttta
     4441 aggacgagga agttctcctc ctcatgtaag gagatacgaa ccgtgccccc gtcttccgta
     4501 tacttaaatg cgttggaaat cagatttgct aggatcttct tgaaatagac ggaatccgta
     4561 ttccaataaa gctctttggg agcatcgatc ttgaattgga tttggtgttg ctcggatagt
     4621 gggtaaaacc attcgaattg agttcgcaaa agagaggata cggatactct ccggatgtgc
     4681 gtatgactga atcctgcgtc ttctgctttc cggaaatcaa ggatttcttg gataagtccg
     4741 ttcagttcct ctacattttc ccggaggact gaagtgtatt tttctaatgt cttgtctttt
     4801 gaggtggcgg cataggcttg gatataattc tccacgccat tgatcaaggt aagcggggtg
     4861 catagctcat gcgtaatgtg ggtaaagaaa ttcagcttgg actcgtatag cttctctttt
     4921 tgctcctcct tgatcttgtc tgcgatctgc ttctgtttct ttagtatttg gtgatggata
     4981 cgataggtgg cgatgatgag caaaaccgta ccgataaaaa gatacgtgaa aatggctaac
     5041 gagcttagat aaataggcgg taataccttg ataggtagag tgtattcttt tgctgacgaa
     5101 tcaatgacat cgttgcgata acggactttc agcaaatatt ccccgtacgg taggttcatg
     5161 aaagttacct tgtttgtctt ttgcaatttt tcccaagagg aattatagtt gaccaactga
     5221 tacgaatact cgtaattctc cccgttgatg taatccggag cgacgaacgc aatcgttaac
     5281 gattgcacat cagccggaac cgttacaccg ttccggctga tgtccttata taatggaagg
     5341 atttgtttat ccatttgcaa ctcgaagaaa cttaattcgg gttgataggt atgctccggc
     5401 tccgtttgtt tatttaccca gactaatccg ttgatgcctc caaagaataa acgctcggag
     5461 tatgggcatt tccaataagc gtcatcagag aattccgtga cgctaaagta aggctgatga
     5521 taattatgga aaaagttgtt ccggggatta tatttggtga gacctttatt ggtactaagc
     5581 cagatacagc tatcgttccc ctcatggata ccatggatca tgtcgtttac gatcccgtcg
     5641 cttttatcga attggcgtaa acgcatcttt ccccctctga atttaatccg ggtgagaccg
     5701 gagctggcgc ctgcataaaa cgtggaatct tcggtctggc atacggaaag cacatctcca
     5761 atggccgggt ttcttaaatt gttggtttgc aggaattcat atccttgatt gaaaatattg
     5821 aaacgaatga ctccgtaacc gccacggctc ccgaggaaca gggtagagtc gttgtcatat
     5881 accatcgatt ggatttcttt acagatgttc tttccgtttt ttaacgggaa ggtttgtacc
     5941 ttcccgattg taggtacggc tttatctata tgtaaggtaa ccttttgcaa tccgttaccc
     6001 gttgtcgcta gccataatgt ggaatcatct acctcgcaaa tagagtggac atagcgtaga
     6061 ggggtggtgt cttctcgttg cggtatcgtt tttattcgtt tctctttata cgaataatag
     6121 gtcagtcccg ggccttccgt gccaatccag atacatggat ggtactcgct tttttggaaa
     6181 caatacacac ggttgctgga taggccgtcg gcggtggtaa aatgcgtgat agcgctttgt
     6241 gggatcatct ttttgttatg gtaagtgtca tacgcttgta tccggacaat accgtctcct
     6301 tttgtcccga gccaaaggga ttgatcgtca tctgtatata aagaacgtat ggggttctgt
     6361 atattaatcg gtaaatcctt gagtaagata gagccgaaaa gatcgggttt gtcataaaac
     6421 atccgtatac cttgcccgtc tgttcccaac cagagaatct cctgcctttt atcgttcatt
     6481 aggcaaaaga taccgatgcc catatttatc gtgttttccg gttggcttag gtctagaata
     6541 ttgccgttac ggaaaacgat atacacattg gattggaagg tgcatatctt gatgatgtta
     6601 ccatattgtt ttgtcatttc aggcagatcg aacaggaatt ctttcccctt tccgtctaca
     6661 tgctgtcgat ataatttatt gtcggtatct actatgaaaa tatgattatt ctcgtaaaat
     6721 gcggataaga tcggtttatt atggaattgg cgttcttccg atagcaaatt aaaagtagta
     6781 tcggagaaat ccggagtcaa ctttttcagt atgcccgagg ctaataataa ataaaaatgt
     6841 ccgtccgtcc cggcgaataa ggtacgtacg gtttgagggc ctactccttc tctcggcagg
     6901 tcccggaacc catcgctaga tggggtgtag caagagatcc tgttttcctt acaaatagcg
     6961 agcgtgatgc cggatgaatc ggacgctaat agatcgcatt ccatgtatcc ggggaaagac
     7021 tcggtgactt tccgttcttt tagtgagaat ttattgatac ctaaagaggt tgatatccat
     7081 aaaaagccgg gttctgcgtc ggatattttg tgaatgatat tactacaaag agagtttttg
     7141 ttatttaatt cgaaacgata tacatacgta tcttttccgt tgtataagtt aagtccgtcg
     7201 taagtcccga tccacaaata gccatccgga tcttgatgca tgcaaataat agcgttattt
     7261 gagagatcaa ccatagaagt tttatgcaat acggttgagg caaataggtc tgtttgcgtg
     7321 atcaatataa ggaaactggt taacgctaga ataagccttg tgaatctcat gtatttaaga
     7381 tttagtgttt gttttcagcg caaagataat atctttatga acgaacagaa aagaattcac
     7441 ttttttgttt acttttgcaa aaagcagggc tttcgtataa attagaatgt ctgacgtatg
     7501 ataatacgaa ataaagtaag tgacagatgg aacaatgtga agagaattct caagaaaatg
     7561 acgatgtgat aatagagaaa gaaatttcta aattaataga agaacagcgt ttatttacgg
     7621 agagtatata tgcttgtctg ccggtgggta ttgaaattta tgacgcacat ggtgtgctgc
     7681 gtagtataaa cgaccatgcg ttgaggatgt atggtgtgga cgaccggaca tcggtggtga
     7741 atatagtcaa tctttacaaa agtccatttg ttgattcaga acttttagct cggatacaat
     7801 cgggtgaaga tatttccttg gagtttgagt atgattttga tcgggttaat aaggatgcat
     7861 attattcttc ccataataaa gacacgatga tctatggggt taaagttatc ccgatatgga
     7921 gtagaaaaaa acatcttatc ggacatatat tactcgcaaa tgatatgact tccgtgaaag
     7981 aggtggaatt ccgtacggaa gaaagcaaga aaaatctgga gatggccatg aaagcggcta
     8041 atatggcttc ttgggtatat gatgtgaata aaaaggtttt taatccatta tatggactaa
     8101 ccgtagccaa aaaaaatatg ccaatggagg cggtactgga tattttgcat ccccaagatc
     8161 gagctccgtt aatccggctc ttctctcaat tgataggaaa tgagatagaa caaggacaaa
     8221 tgactttgcg tttctataac gagcaagaag agatgtatcg ttattatgag agccggatgc
     8281 gcctatcgac agaacatcgt ggaaaattgc agatcatcgg gacacaaatg gatataaccg
     8341 aaaggttgca aatggccaag aaagcgcagg atctgatcgc aaaacgtgat ctggccatga
     8401 aagtcagtaa tattgttcat tgggattttg atgtaaattc ccagaaattc gaatcttata
     8461 atgatccgat caacgattac gtttcagatc ggttattgac cgtttcggag tatatggatg
     8521 ttatataccc cgaggaccgg tctgtttttt acgacgcaat gcaatccctg atagctggaa
     8581 agaatgtcac catcaatttt acctgtcgca tacaaaccaa gtatgatgag acttggcagt
     8641 attgtgattt tatgggtgtc cctttcgatc aagatgaaaa tggagatata atacgctata
     8701 cgggattcag gcaaaacatt cctaagatcc agcaattgaa tcgggaactt aaagaaagaa
     8761 attacaagat agagctttct ttcaagacgg ttggtatgtc gtattgggat tttgatgtaa
     8821 aaagcctgaa attcagtgct tttaatgatc ctatcaatga tttttattcg gaaaagacaa
     8881 tcactcccga ggattatttg aacgctacac atccggatga tgtggttttt gtgcggaaat
     8941 atatggagca tatgttccgg ggcatagata aagatttcaa cgttaaatat cgttccaaaa
     9001 ccaaatggga tgacgagtgg cagaccttat tggttactgg aatccaggtt gaaagagata
     9061 aagaaggcca tgtgactcgc tataccggta ttacgatcaa taatacgaag tgggagaaga
     9121 tgattcagca attgaaggaa ttaaaggaga aagcggaact ttcggatcgt ctcaagtctg
     9181 cgtttctcgc taatatgagt cacgagatac gtactccgtt aaacgctatt gttggttttt
     9241 cagagttaat ggtaacttgt gatgatccgg aagaaaaaaa agaatatata aatatcatcc
     9301 aatccaataa tgagttgtta ttgcgattga tcaacgatat ccttgatctt tccaagatag
     9361 agtcaggcat aattgaacgt aggaaggaga atttcaatct ggctaaggtt tgtaatgagt
     9421 tatttgttac gattcaggcg aagatgacaa atccgaatgt cgagttacgt ttagatggtc
     9481 ccaactcgga gtgctgggta cttctggata gaaaccggct taagcaagta tggatgaatt
     9541 tcctcactaa tgcggtaaaa tgcaccaaat ccggatatat taaaatggga tatggcattg
     9601 aaagggaagg tcttcgtatc tatgttgagg atacgggaat cggtataccg gatgatttgc
     9661 atgacaaagt atttacccgt tttgagaaat tgaatgagtt ctcgcagggt accggacttg
     9721 gcttgacgat ctccagagct atcgtagaag cggcaggggg agaagtgggc ttcacttcaa
     9781 aacttggtgt cggatctact ttttgggcat ggttgcctct tcgcccttag gtctgactcc
     9841 ccatttattg gtaatgtcct tttaaaatag tgaaggatga gaagcttttt tatcgcaatt
     9901 tatagggatt ttagaactgg tgtagcatat gtgacagaaa tatgacgata attctcctac
     9961 ctttgcggcg gtaaaaatgt ggtattagat aagattgttt atgaaatttg agaatgagtg
    10021 ctgggatcac tttaagggtg agacctggaa aagagagatc aatgtaagag attttatcca
    10081 gagtaactat acgccttatg aaggggatga ttccttttta gtcgcttctt ccgagaagac
    10141 ccgtaaggtc tggaacaagc tgaccgagat gtttaaggtc gagagggaaa agggagttta
    10201 tgacgtcgag acaaaattac ctcaagggat cgatgtatat ggcccgggct atattgataa
    10261 ggagaatgag gttatcgttg ggttacaaac cgatgctccg ctgaaacgtg gtatcttccc
    10321 gaagggcggt atccgtatgg ttgagaatag cttggaagct tatggttatc atttggaccc
    10381 gatgacgaaa gagatcttca cgaagtatcg taagacgcat aacgagggcg ttttctccgc
    10441 atatacggaa gagatgattg ccgcacgtcg ttcggctatt atcaccggtc tgcccgatgc
    10501 gtatggtaga ggacgtatta ttggtgacta tcgtcgtgtc gctttatatg gtacggcaat
    10561 cttgatcgag gagaaaaagc gtttcttgaa tcgtttggat atccaagaga tcacggaaga
    10621 gatcatccag agccgtgagg agatttccga acagatcaag gctttgaaag cgttcgagaa
    10681 aatgtgcgct agctatggct ttgatgtgac tcgtccggca caaaacgctc gtgaggcggt
    10741 tcagtttgtg tacttagctt atctggcggc ggtaaaagac caagatggcg cggcgatgtc
    10801 tatcggacgt acttctacgt ttttggatat ttatatcgag aaagacatcc gtgagggtaa
    10861 gttgaccgaa gaggaggcgc aagaattggt agaccagctg atcatcaagt tgcgtatcgt
    10921 tcgtttctta cgtacgccgg aatacaatga tttgttctcc ggtgatccgg tttgggtaac
    10981 agagtccttg ggcggccaag gagtggatgg ccgttctttg gtaacaagaa cttcctatcg
    11041 ttatctccat acattatata atctaggtcc ggcaccagaa cccaatttga cagttctgtg
    11101 gtttaagaac gctcccgaga actggaaacg cttctgtgcc aaggtctcta tcgatacatc
    11161 ggctatccaa tatgagaacg acgatttgat gcgtccggat tatggagatg attatggtat
    11221 cgcttgttgc gtttctccta tgaagatcgg taagcagatg cagttcttcg gagcccgtgc
    11281 gaatttggcg aaatgtttat tatatgcgat caacggagga cgggatgagc gcagcggcgt
    11341 acaggtagcc ccgatgttcg agccggttcg cggcgagtat ctggaatacg atgaggtgat
    11401 ggctaagtat gagcaaatga tgcgctggtt ggcgaaagtg tatgtgaacg ccttgaagat
    11461 aatccattat atgcatgata aatatgcgta tgaggcattc gagatgtcgc ttcacgatgg
    11521 ggatgtagag cgtatccgtg cgacaggtat cgccggtctt tctatcgttt cgttggctgc
    11581 tatccgtgat acgaaagtac gtgtgatccg tgacgagcgt ggcttggcgg ttgatttcga
    11641 acgtgagggc gaatatgttc ctttcggtaa taacgatgat cgtacggata gtatcgctgt
    11701 agagatcacc gagaagttca tggaatattt gcgtcagcac gagacctatc gccatgcgaa
    11761 acctacgcag tccatcctta cgatcacctc taatgtggta tatggtaaga agactggtac
    11821 gacaccggat ggccgtatcg gtggaactcc tttcgctccg ggcgcgaacc ctatgaacgg
    11881 tcgtgatacg aaaggtgcta tcgctgcgct agcttcggta gcgaagcttc cattccagca
    11941 tgcgcacgac ggtatctctt atactttcgc tgtttctccg gctacgttgg gaaaggagcg
    12001 tgaagtgcag atcaataatc tggttagctt attggatggc tattttactc cggatggagg
    12061 tcagcatctg aatgttaacg tatttgataa ggatttgttg atcgacgcta tggagcatcc
    12121 cgagaaatat ccgcaactta cgatccgtgt atccggatat gcggtaaact tcgtgaaact
    12181 gactcgtgaa caacagttgg atgttatttc aagaaccatt aaccattcac tgtaagtgat
    12241 aaaaggtaag atacattcat tagagagttt cgggaccgta gatggtcccg gaattcgctt
    12301 tgtcgttttt atgcagggct gcccgttgcg ttgcctgtat tgccataacc cggatacttg
    12361 gaccccgaaa gggaaggtga aatatcagat gactcccggc gagctattga cggaagtctt
    12421 acggtataag agttttatcg cccgtggggg ggtgactgtt accggtgggg aacctttatt
    12481 gcaacctgag tttctgaaag agtttttccg tttgtgccaa gagcaaggtc ttcacacagc
    12541 tttggacaca tctggtttcg tatgtacctc aaaagcttgg gaagtcttgg attatgcgga
    12601 cttagtgtta ttggacatca aaaccttaaa cccggattta catccgttac tggcgggtgt
    12661 caagcaggat aatacgcttc tgttcttgga tgaattggag agacgtggca tagatacttg
    12721 gattcgccat gttattgtcc ccggatatac ggataatgac gagtggctgg aggcgttagc
    12781 tcggtatgtc agttcatata aagtggttcg caaagtggaa ttattgtctt atcatacgat
    12841 gggaacctat aaatatgagc aattaggcct tgattatccg ttaaaggggg tggaaccctt
    12901 atcaaaagaa cgtttagata atgcgaaagc gatattctct cgctacaaac cagaaaataa
    12961 caaggcctga tctctcgatc aagccttgcg attatgcaac agctaatcag ggaaaacaat
    13021 ctaatccgat tagcttttaa acgatagtaa taattttttg cctagactaa ccttgactat
    13081 ttaatatgtg tttgttttgt tatatgcaac aaatatctat ttttgtaagg agataaaaaa
    13141 tgatatagat cagaaaatga tgaatagtat gaagacacca caagaaatag ccgaaatgat
    13201 atccaaacgt ttttatccat tacccgatgc ggatttggat tctctggctt cgatcataga
    13261 atcaagtaag gctgcgaaag gagaattatt gttggataac ggacaaatat ctaaatattt
    13321 atattatgtg gaatcgggat tattacgcca gttttactat aagaataaac gtgatattac
    13381 cgagcatttc tcctgtgagg gaaatatcgt tatttgtata gccagcacat tccaaagaga
    13441 accgacgcgt ttattaatcg aggcattgga accgacggtt tatcaccgga tctctttttc
    13501 ggaatttagc gatttattga aaacatcttt agctattaat agattgtacc agaaaatact
    13561 ggagtgggct ttgatgcttt cgcaagagaa agcggactct tggcgttttg agtcggcaag
    13621 aaaacgttat ctgcgttttc aacaggaata tccggaagca gcgaaacgtg cttctgtcaa
    13681 tcatatcgcc tcgtatttat tgatgacacc cgaatctttg agccgggtac gggcgggagt
    13741 gttataatcg ttactgatgc ggtaatccaa aacccaagat attgaagggc ttatccgtga
    13801 ggataggccc tttttattga ttgataaagt attatctata acctcataaa atatatcgat
    13861 taaaaaaatt gttttaatga agaaatatgt tatatttttg tatcggaaat aaaaacaaat
    13921 agtattcatt taaaaatagg aacaagtatg gagccgatta ttaattctca acttccggag
    13981 tttaaagtac aagcttttca aaatggtaat ttcaagactg taaccaacga ggacgtcttg
    14041 ggtaagtggg ctatcttttt cttctacccg gccgatttta catttgtttg tccaacagag
    14101 ttggtcgata tggctgagaa gtatgagcag tttaaatcaa tgggagtaga aatttactct
    14161 gtaagtacag attctcattt tgtacataaa gcttggcatg acgcttccga gactatccgt
    14221 aagatccaat atccgatgtt ggcggatccc actggagcgc tgagtcgtgc gtttggtgtg
    14281 atgattgagg aagagggtat ggcataccgt ggcactttct tggtaaatcc ggaaggaaag
    14341 atcaaagtgg ccgagattca tgataacaat atcggtcgtg acgcttccga gttacttcgt
    14401 aaagttgaag ccgctcagtt tgtcgcttca catgatggtg aggtttgtcc tgctaaatgg
    14461 aagaaagggg aggctacctt gaaacctagc attgacttgg tagggaaaat ctaaataatt
    14521 aagagtatag atcgtgttag aatcaatatt aaaagaacaa ttaaaaggta tattcgcagg
    14581 gttaaatgcg aattatacct ttgatatatc gatctctcct gcgcatgaaa gtagacagga
    14641 attgttggat ttattaggtg atgttgcctc ttgttcggat aaaatatcta tgcgagtatc
    14701 tgatggggag ggattggaat tcattttatt aaaggatgga gcgaaaacgg ggattaagtt
    14761 tcgtggagta cctaatggac acgagtttac ttccttgctg ttggcgatct tgaattcaga
    14821 tgggaaaggc aagaattttc cggacgagag catttgtaat cgtgttaaag ccttgaatgg
    14881 cccgatacat ctgacgacct atgtctcttt gacttgtacg aattgcccgg atgtggtaca
    14941 ggcattaaac gctatgacga ctttaaatcc tcagatccat catgagatgg tagatggggc
    15001 tatcaatcag gcggaagttg atgccttgaa gatacaaggc gtcccctccg tttttgcgga
    15061 cgggaaactg atccatgtag gacgtgggga attcggtgaa ttgttatcga agctggaagc
    15121 tcagtatgga atcaatgaga gcctgacaga gaagacggta aaacgatatg acgtggttgt
    15181 ggtcggtgga gggccggctg gtgcttcttc cgctatttat tccgcacgaa aggggctgag
    15241 tgtcgctgtc gtggcggagc gtatcggcgg gcaggtgaag gagacggtag gaattgagaa
    15301 tctgatttca gttccggaga caacaggtac ccagttggct gacaatctgc gcttgcatat
    15361 gcggcaatat ccgattgacc tgctggagca tcgtcgtata gagaaggtaa cgatagaagg
    15421 aaacgagaag gttttgtcta cggctggagg tgagatattc aaggctccgg cggttattat
    15481 cgctacgggc gctagctggc gtaaattgaa tgtaccgggt gaggcagagt atatagggcg
    15541 tggctttttg tcctcattgc gacggtccgt tttataaggg aaaacatgtc gccgtggttg
    15601 gcggtggaaa ttccggtatc gaggcggcta ttgatttggc ggggatctgt tcgaaagtaa
    15661 ccgttttgga gtttatggat gagttaaaag cggatcaagt cttgcaagag aaagcgaaga
    15721 gtttgccgaa tgtcgagatc tttgttagtt cacaaacaac cgaggtggtt ggaaatggcg
    15781 acaaggtaac cggtatccgt acaaaggatc gtaagacagg ggaagagcgt gttattcatt
    15841 tagacggtat ttttgttcaa atcggcttag ccgctaatag tggtgtcttt aaggagattg
    15901 tcgaaacaaa tcgtcccggt gagatcgtga ttgacgcaca ttgccggacg aatgtcccgg
    15961 gtatttatgc agcgggcgac gtttccaccg taccctttaa gcaaatcatt atttctatgg
    16021 gagaaggcgc caaagcggcc ctttcggcct ttgaagatcg ggtacgtggc gtacttgatt
    16081 gaggaaagta cctacaaata ggtaattttt gaacagcgta tctcttttat cggttatatt
    16141 actatatttg cgatcgagag aaaagagatg gatagattaa ga
//
