LOCUS       c00016_gnlPro..        13689 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OLPBGAJB_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:54:51
            Original ID  :: gnl|Prokka|OLPBGAJB_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13689
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13689
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[199:3689]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      200..3689
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13689
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13689
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(200..1030)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.2e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.5e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1008..2966)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.1e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2988..3689)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.4e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3890..4162
                     /locus_tag="ctg16_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4165..4980
                     /locus_tag="ctg16_5"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5014..5247)
                     /locus_tag="ctg16_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5677..6384)
                     /locus_tag="ctg16_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6415..6504)
                     /locus_tag="ctg16_8"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             6580..7419
                     /locus_tag="ctg16_9"
                     /transl_table=11
                     /translation="MIDLASFSLLDGFQIRLGNSKFATSCHPKGIINMKKTLTFLIAMG
                     SFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGLGSSSLAPSDSSSPSSLSGEIRLDSFT
                     LRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLTFSFSSLDGSPLLLDAA
                     LTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAPTANTEGDTVTISGGLTAPGIRGHYDA
                     EGAPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLGLLGLAALMMRRRRA"
     CDS             7446..7727
                     /locus_tag="ctg16_10"
                     /transl_table=11
                     /translation="MRAVLAEQLLFFISREEELLIRMRDSCPPEGTEFPGAGGRIRFSP
                     HGGNLLETFLRRNTGKLFLYRKMPVKFGSALFVHMVHGSFHIAAFQAG"
     CDS             7869..8054
                     /locus_tag="ctg16_11"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCIQLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(8098..9303)
                     /locus_tag="ctg16_12"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             complement(9327..10073)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_13"
                     /sec_met_domain="adh_short_C2 (E-value: 2.2e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10200..10718)
                     /locus_tag="ctg16_14"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLAEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10782..12257)
                     /locus_tag="ctg16_15"
                     /transl_table=11
                     /translation="MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITP
                     EMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRP
                     AREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHD
                     RDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFID
                     RFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSY
                     GDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFS
                     QARTENLNPENTVLEEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLS
                     LVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLH
                     VNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12322..12468
                     /locus_tag="ctg16_16"
                     /transl_table=11
                     /translation="MVISVSLNKVRPAWDFVRFLIVSMVKRGCILPGWKGEGKSRQGGG
                     RHF"
     CDS             12632..13222
                     /locus_tag="ctg16_17"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPILVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 ggtttcgtcc ggcattgcca agtacggtct cctggattac tgggggcctt ccggtgtaac
       61 aattttttac gctgcgcgac gatgaggaag caactgtctg gtattttatt cctggttcaa
      121 ggaaatctgg taatgaaaaa actcccgaca gccgatgccg ccgggagttt ttacagagcg
      181 tcttaagaag gaatcttctt tagaaacaga ggccttcctt ggcgttggcc cgcatgaagt
      241 cgcggttgag gcgggcgatg ttgtccacgc tgatgccttt cgggcaggcg gcttcacatt
      301 catactggtt cgtgcagttg ccgaagcctt ccgcttccat ctgcttcatc atggccagga
      361 cgcgcttgga acgttccggc tggccctgcg gcagcagatt gagatgggcg atcttggcgg
      421 aggtgaacag catggcggag gcgtttttac aggaggccac gcaggcgccg cagccgatgc
      481 aggcggccgc gtcaaaggcg gcgtccgcct tcactttttc cacggcgatg ttgttggcgt
      541 tcggcgcgga accggtacgc acgtcaatat agcctccggc ggcgatgatg cggtccaggg
      601 cggagcggtc caccatcagg tcccgcagga ttgggaaagc cttcgcgcgg aagggttcaa
      661 tccagacggt atcgccgtcc ttgaacttgc gcatgtgaag ctggcaagtg gtcacctggc
      721 gttccggccc gtggggaatg ccgttgatgg tcagggagca catgccgcag atgccttccc
      781 ggcagtcgtg gtcaaaatgg atgggttcct tgccttcctt gaccaggcct tcattgacga
      841 tgtccagcat ttccaggaag gaggcgtcca ccggaatgtc cttggcggca taggtctcaa
      901 tgcggccctt ggcttcccgg ttttcctggc gccagacctt gagagtgaga ttgagtgttt
      961 tagccatgtt ataatctttc ttttgagtgt taatgtattg gctatcttta cttgtagctg
     1021 cggatggcaa ggtgcacgtt ctcgaaggtc agcggttcct tgtggagaac aggcaggctg
     1081 tccacgccag tgtattccca ggcggctaca taggcgtatt catcgtcgtt gcgcttggct
     1141 tcgccgtccg gcagctggta ttccacgcgg aagtgggcgc cgcaggattc ctggcggttc
     1201 agggcgtcat agcagagcag ctgggcgaat tccaggaagt cggccacgcg gcaggctttt
     1261 tccagttccg cgttgatgcc gtccgccgtg ccggttacgc gcacgttttc ccagaattcc
     1321 ttgcggagct ggggaatgcg ttcaatggcg tgggtcaggc tttcttccgt gcgggccatg
     1381 ccgcagtctt cccacatgat gaggcccagt tcccggtgga aggagtccac cgtcttggtg
     1441 cccttcacat tcaggagctt gttgatgcgt tccttcactt cgtcttccgc agccttgaat
     1501 tccggggcgg cggtggtgac ggcgccgggc ttggtggtcg tcaggtaagc gggcagcgtg
     1561 gcgggaatga cgaagtagcc gtcagacagg ccctgcatca gggcggaggc tcccaggcgg
     1621 ttggcgccgt ggtcggagaa gttggcttca ccgaggacgt gcaacccctt cacgttggac
     1681 atgaggttgt agtccaccca caggccgccc atggtgtagt gggaggcggg gtagatcatc
     1741 atgggcgttt catgggggtc gtcgtccgtg atttcttcgt acatgtcaaa cagattgccg
     1801 tattggccgt caatccattc gcggcccatg cgcttgattt catccgcaaa atccaggaag
     1861 acgcccttgc cggtgacggc cacgccgcgg ccgtcgtcgc aggcttcctt ggcggcgcgg
     1921 gaggaaatgt cgcgcggagc caggttgccg aaggagggat acttgcgttc caggtagtag
     1981 tcccgttctt cttcgggaac atcggaaggc ttgatttcct tcttacggat tttttctgcg
     2041 gtttcacggg acttgggcac ccagatgcgg ccgctgttgc ggagggattc cgacatcagc
     2101 gtcagtttgg actggtagtc gcctttgacc ggaatgcagg tggggtggat ttgcgtgaag
     2161 caggggttgg cgaagaaggc accacgcttg taggctttgt aggcggcagt gacgttgcaa
     2221 cccatcgcgt tggtggacag gaagaacacg ttgccgtagc cgcccgtgca gagcaggacg
     2281 gtatcccctg cgtaggattt gatttcgccg gtaaccagat tgcgggtgac gatgcccttg
     2341 gcttcgccgt ccaccaacac cagatccatc atttcatggc gggagaacat ttcaatgtgt
     2401 cccttggcca cttccttttc cagggcctgg taggcaccca gcaggagctg ctggcccgtc
     2461 tgtccgcgtg cgtagaaggt tcgcttgagc tgggcgccgc cgaaggagcg gttgtccagc
     2521 aggccgccgt attcacggcc gaagggaacg ccctgggcca cacactggtc aatgatgttg
     2581 gaggagactt ccgccagacg gtagacattg gcttcacggg cgcggaagtc gccgccttta
     2641 acggtgtcgt aaaacaggcg gtaaacggag tcgccgtcgt tctggtagtt cttggccgcg
     2701 ttaatgccgc cctgggccgc aatggagtgg gcgcggcggg ggctgtcctg gtagcagaag
     2761 catttgacgt tgtagccaag ttcggcaagc gtggcggcag cggaggcgcc agccaggccg
     2821 gaacctacca caagcaccgt gtacttgcgc ttgttgttcg gattgatcag tttggactca
     2881 agtttgtact tggaccattt gtcctgaata gggccggagg gaattttggc atccggcatc
     2941 cagtcgctta cgggaaaatt aatcatgact ttgagaggag ttgatggtta tttgatgata
     3001 cccagaagaa ccgagaccgg cacggagatg aagcccaggc agataatcgc gccgtaggcg
     3061 atggcgataa agttgtagaa gggccggatt ttgcgggaat cgacgcccac agtctggaag
     3121 atggactgta ccccgtggcg cagatggctg aacagcatca gaacggccag gatgtagaag
     3181 gcggagcacc atacgttgga gaatccggtc acgatcatct tgtacacgtc aaaggtttcc
     3241 accgtaccgt cggaaataaa ggtggtgaac tgggcggggt cgtatcccac gcgcagggtg
     3301 tactggtaca ggtggtagat caggaacacc aggacggtca aaccggtata gatcatgtag
     3361 cgggaggaga gcgttgcctt aatggtgttc ttgaacacgt agggttcgcg ggccgcatgg
     3421 ttttccagct tcagctggat ggtcagccag acgtggatga tgaagatcac cgcaagcccc
     3481 gcgcggattc cccagagggc tgcttccggc atggagtgca ggccgtgggc gtaggtgttg
     3541 atccattcag ggcctccgaa gatgagaagg ttgcctgcca ggtgtcccgc aaggaacaag
     3601 accaaacata accccgtcag agccacaatg attttgcggc cgatggagga tgtcacgaat
     3661 gtacatatgg tttttactag tgcattcata ggcgctctaa tgaaataaat gcgtcttcac
     3721 aggatgcccg gttcaagccc ggatggcaag cctcttcttg aatttccggc gcttttcgga
     3781 tttttgaaaa accggggaaa gaggttgctg tttatcagtt tggaatggtt atcattttgt
     3841 tgcctgttcc ggcttgacga ggctttccgc ataggcgtat cgtctgtgca tgaaaagaag
     3901 taaaaaggag gtgctggacg cggatttcgc agcggcgcgc gccggcgttc tggatgtggc
     3961 cgcatttctg gaccgggtgg accgcgggga aggggaggcg gatttccgct accatgccct
     4021 gatggatgtt cttcccctct tgtccgcatc cggccccgga cgcgtccggg ccattctgga
     4081 agccctttcc tacagggatg acaccgtgcc ggaaaccgcc gcagccaaag cggcctgcgg
     4141 agccccgaac ctcagcaaat aagaatgatg gctttcatag aacctcatat acatatggtg
     4201 tgccgcacca cggacgaata ccgggccatg gcgcaggccg gctgcctggc ggtaggggaa
     4261 ccggcgttct gggccggtta cgaccgttcg tccgcggacg gtttccggga ttatttcgta
     4321 cagcttacgg aatgcgaacc cgccagggcg gccaagttcg gcatggacca ttacacatgg
     4381 ctgtgcatca atcccaagga ggcgcaggac gtggctttcg cgcgggatgt gatgaaactg
     4441 attccggagt tcattgaccg gcccaatgtc ctcggcatcg gggaaatagg gctgaaccgg
     4501 aatacttccc atgaaatgac tatttttgaa gagcatctgg atctggcggt gcgcctcaac
     4561 cagcttgtgc tgattcacac tccccatctg gaagacaagc ttaaggggac cgtaatgatt
     4621 ctttccgccc tgaaaaaccg tccggatctg gacccttgcc gcgtgctggt ggatcactgt
     4681 gaggaacata ccttcccgct ggtgaaggag gccggttact gggccgggct gaccctttat
     4741 cccaccagca agctgaatcc caagcgggcg gcggatattc tggaattgta cggaatggac
     4801 cgtgtctggg ccaattccgc ggcggactgg ggggattccg atcccctggc gctgacggcc
     4861 ctggcctgcg agctacgcag gcgcggtttt tcccggcagg aaacggaacg tcttctcctg
     4921 gaaaatccgg agacattcat gggacagtcc ccgaagttcc ggaaagtgtc gtcccgctaa
     4981 ttccgcccga ggcgcggcgg agggtacggc cctctagtcc ccgtccggga aaaagacggt
     5041 gaggacggcg cccaggatga ccgccgcgtc atccagaagg cccagcctgc cgattccgtc
     5101 aaacaggaat tcgtcgggag tcaggatgta ggcgccggcg gcggccagaa ggcatatatt
     5161 ccgtttgttg aaaaaacgcg gttctccttt tctgcttttg aaataccgga acaggcgcag
     5221 tagcagctgc tgtttttgaa ggttcatgga tgggaacggg ggataaaggt tcaagttcag
     5281 ccattttccc actccttttc cctgtttcag ggaaggagtc tgttgccgac ggacggaaac
     5341 cgcagcgatc cggaccgtgc ggggaaatgg attgctgaaa ggatgggctg ttccggatgc
     5401 tgagggaagc cgggctttgc atgctccggt tccggctgtc ccggcatggg aaaaaggggc
     5461 gtgtacggaa gtggggcggg gccggaagct cttgaaatga ccctcccggg ggagcctgaa
     5521 tgccatttcc ccgtcaagtg ctggccgtga gggtacccag caaatagaag cttcttcccc
     5581 ctgttttttc cggcagatgt ttgaacggat aaggaaaagg ccggctcacg attttgtgag
     5641 ccggcctttg aatataggga ggcggacggt acaggcttat gccctgcggc ggcgcatcat
     5701 cagcgcggcc agtcccagca ggcccaggga agccgtggcg ggttccggaa tgctggcgat
     5761 ttcactcatc agctgaccaa cttgttcctg ggaaaggagg gagtcgtgga tgtagagctg
     5821 ttcgatggat tcagccagtc ctgcgtccat gagaatctga ttaatttgct ggttgccgaa
     5881 tttcaggccg ctgttggaat agtacgtagc gctgtctcca aaatagatgc gggtgccaag
     5941 atctccggtg actacggaaa tggtcaggga accttccgtg cccagcgggg tgtcaacgac
     6001 gggcccgctg tatgaggtgt tgttccataa tccctggagt ttccggtccg tgttcaggcc
     6061 cacgccccag cttacactgc tgtttttggc gttaaacaga gcggtatagg tctccggagt
     6121 gttgattttg gacaggtcaa gaaccatcgt cacagacata acgtcgcggt tgttggcacc
     6181 gtatccgttg aaggttatcc cggacaacgt cagattgctg tcgtcagacg tgatggaaac
     6241 ggaatctttc cgggtgccga aatccgccgt ttgggaggca aagtccgaat atcccacgat
     6301 ggagctatcc aacagagcgg tagccgcggt agcgctcagg ctcatgccgg ccgaaagaat
     6361 cagggtggat aataatttat tcatggtcag tatcttaata aaatgattca aggttcaatg
     6421 tatgtacttg tgcttgaata acgaatttgg aatccgcaag caattaaaaa tattaagagt
     6481 tagtatattg tatttataat tcattgaaaa taatgatttt ttaatatctc tggtcctttt
     6541 gtcaagatga cgggtcagtc tttgttattc attggtttca tgattgattt ggcctctttt
     6601 tcattacttg acggattcca aatccgattg gggaattcca aattcgctac aagttgccat
     6661 ccaaaaggaa taataaatat gaagaaaaca ctgacatttt taatcgcgat gggaagcttt
     6721 gctgtttcct cggaggcagc gaccgttttt aattattaca ctcccggtac ggataattac
     6781 aatagtacca tccatgggtt ttatcttggc ctggggtctt cttccctggc tccttccgat
     6841 tcctcttctc cctcctccct gtccggagag atcagactgg acagttttac gctgcgcgga
     6901 gccgccaaca atttgggcgc taatgtcact tacggcttcc tggtgctgaa tggctccgac
     6961 aattcggtca tcggctggag caccaatacg ggaactactg cagcagggat taatctgacg
     7021 ttcagttttt cttccctgga tggttctccc ctgcttcttg acgcggcatt gacataccgt
     7081 ttcctggccg tgagccagtc cgtgatggac ttgatgcagg atacgtctaa aacgtattta
     7141 tatgctgcgg ggggaacagc cgcccctact gctaacacgg aaggagatac cgtaacgatc
     7201 agcggcggat tgactgctcc cggcatccgc ggccattatg acgccgaggg agcgcctggt
     7261 gattctgtcg ttattacggg agccaacgga accaatactt tcagcttatt atccccgatt
     7321 ttcacggaaa tccgagggga aatggtgccg gaaccagcca cggtttccct gggcctgctg
     7381 ggactggccg cgctgatgat gcgccgccgc agggcttgag cttcctgatg gcgaaaaatc
     7441 ggcggatgag agctgttctt gcggaacagc tcttgttttt tatatccaga gaggaagaat
     7501 tgcttatccg tatgcgggat tcatgccctc cggaaggtac ggaatttccg ggggcagggg
     7561 gccgtatccg gttttctccg catggcggca atttgctgga aacgtttttg agacgcaata
     7621 ccggaaagct ttttctttac cggaaaatgc cggtcaaatt cggcagcgcg cttttcgtcc
     7681 atatggtaca cggcagcttc cacatagcgg cctttcaggc cggataggga acccctttgc
     7741 agcgcacaga cctggagggc cgccgcatac ctattatccg ccgtcctatt ccccggcact
     7801 ggtattccgg aagaacggca atgggcccca tgcccagcac ttcatattct tttccatcgt
     7861 ctgccctgat gacggacgtt gcatcaacga tgtttcccga cgatgcggct gccgtggacg
     7921 gcgactgcat ccagctccgg gatgaaggaa ggactgacgc gcatgatatg gagcaggtaa
     7981 tgttcattgc agccggggac gaaatagttt cagaacgctt ctctcgtgac atgttccgtt
     8041 tcggcatggt ctgaggattg ttccgttctt aatgcaatgg tcatgaaaga ttgttcttta
     8101 cggctccccc ttggagaaat tccagaggcg gtgcatcgtc ataacgtccg gaatgttcat
     8161 ggggcgcacc acgcggaacc cgatcatgcc tccgtccgtc aggtaccaga tgcttttagg
     8221 gttttgagga tcctgacggt tccaggcggg ggtgctggcg cggcgcgcag cgcttctcag
     8281 gctgtccggg tcgtcttccc acgaaccgcc gcgaacgatg tgaggggcgc cggggatgat
     8341 gaccaggggg tctttcgcgg gcaatccgct ccgtttgccg taggcatccg gaacgtaaga
     8401 gtccaaaacc cattccgcca catttccgtg catgtcccgg agtccccact tatttggttt
     8461 tttagagcct gttttctggt agcggtcatt ggagttgttc cagtaccagg cgtactggtc
     8521 cagagaggct tccccgtttc cgtaagaata ggcgccgggg gagccggccc ggcaggcgta
     8581 ttcccattcc gcctccgtgg gcaggcggta gtaatgcccg gtctgggcgc tcagccattc
     8641 gcagaatttg ctggcggcgt ggtgggacat ggagatggcg ggcaggccgt gttcatagcc
     8701 gtggcccatg cccaggttca tggcggcgta gggggcggta ggctgcgtaa cggagtccca
     8761 cagttcgtca tccggctgtt cctccagaag ctgaccgtcc ttggcgcgcg gacgcccgtt
     8821 ttccatgaag gccgtataaa gttcccaggg gatttccgtt tccgagatcc agaagggaga
     8881 gatgctcact ttatgctgcg gtccttcgtc cggtttccgg tgcggctctt ccgcgggact
     8941 ccccatgagg aacgttcctc ccggtatggc aaccatgcgc agggaagctc ccgccgcggg
     9001 aaccgtttcc gtgtaggatt caaaacgtgc cggatttccg gaagcttcaa tgagctgatg
     9061 gatttggcgc gtcgtgccga ccagctcccg ggacggcagg tcatccggaa tgggaagggc
     9121 aggaccggca gcgcggtcca gttcccgttt ttgcagcgcg gatcggcttt ctccccactg
     9181 gcgtgcgctg gtaatgcgcg cggcatcttc cgtggccggg cggggggaat tattttcttc
     9241 ccggcacccg gccagcaggg cgcttcctcc cagaaagcag gaaacaagga aaatgccacg
     9301 catggaatgg agaaaaccgg aatgccctac atcgtcatgc ctccgtcgca ggcaatgacc
     9361 tgcccggtga tgtaacgggc atcgtcagag gcaaggaagg ccgtcagggc ggcgatatct
     9421 tccacggaac cttgttcttt caaaggtatt ttcttaacga tttcttcctt gagattgtcg
     9481 ggaatggcat tggacatttc cgtggagatg aagccgggag caatggcgtt gcacgtgact
     9541 ttgcgcggag cgaattcctg tgccagtgat ttggtgaaac cgatgaggcc cgccttggaa
     9601 gcggcgtaat tggcctggcc gatgttgccg acgagaccga tgacggagct catgttgatg
     9661 atgcgcccgg ccggggattt catgagaacg cgctggaggg ccttgaccgt attgaacgcg
     9721 cttttcaggt tggtgtccag aacggcatcc cagtcttcct ctttcatgcg gagcatcagg
     9781 gagtcccgcg tgatgccggc gttgttcacc aggatgtcaa tctgcgggaa gtctttcaaa
     9841 atggcggcca tggtttcctg aacggccgcg taatccgcta cgtcgcaggg gtaggccttg
     9901 caggaatccg gaaattcctt gttgatttct tctgcggccc ccccgcagct ggatggactg
     9961 cggctgatca ggatgaccct ggctccttcc gaagcgaagc ggcgcgcgac ggcattgccg
    10021 attccgcggc ccgcgccggt aacgatggct gttttacctg ctaacttttg catgctgccc
    10081 acagtaaacc cgtttttcac ggttccggca agcttgaaat ggacttggcc gcgcaggaac
    10141 ccatacgggg aaagggcgtg ccgggaatga aaaaagaggg gggagaaacg gggcgggggc
    10201 tactgtccgg cctcttcatt ttcccggagt gcaccggggg gcgccccgtc ttcatccggt
    10261 tctgccaggt cgctgaattc atccgaattt tccaaaatgt cctttaaggc ggcggaaccg
    10321 taatagcggg cctcaaacag gcgtttgcct tcctgcctgc agcggttgtc cagcatttcc
    10381 attcgttttt ccattttttc tatcaaggcg tcttctttct ccttttccgc atcgttcaat
    10441 ttatcctgaa gctggaggaa atgccggatg tccttctgaa tgtcctgcag cgttttgacg
    10501 gcgttgtccg cgctttcctt gtcctgaacg cctgccaacg tctgctggat attgatggca
    10561 aaggaaaagg cctggttgat cagggattcc gcggaaggaa ttttttccgc cggagccgct
    10621 gctgaggggg aagccgttcc ggcggccgtt tcaccaaatg caagagaggc tccggacaga
    10681 agcgcagaat ataagagagg aacaagaaaa gccttcatcc tgttctttta aggcaggatg
    10741 aaatccacgg caaggaaaaa ggggaaactg aaaaaagagc cttattccgc cgtgatgccg
    10801 cctttttcat cgtccagaat gcctgacttt tccagataat agtcatatcc gcctgcgtag
    10861 gcggtgatgg tcccccggtt cacatgcagg gttttttgtg ccagggaacg gatgaagtgc
    10921 acatcgtggg agatgaagac cagtgttcct tcataatgct tcagagcctg caccagggct
    10981 tctacggaca aaaggtccag gtgggtggtc ggctcgtcca tcagcaggag gttgggcgga
    11041 tccaccagga atttgaccag gctgagccgc gatttttccc cgccggaaag aacgctgacg
    11101 cgtttttcca catccagcct ccggaacagg aaggaaccca ggatggaacg cgcttcttcc
    11161 tcccggattt cagcgctgca tttcatgatt tcctccagca cggtattttc cggattcagg
    11221 ttttccgttc gcgcctggga gaagtagccg atgcgcgtcg tggtaccggg agtgcgttgt
    11281 ccggagtcaa tggggatgat gcccgccagg attttgagaa gagtggattt gcctgcgccg
    11341 ttcgggccta caagaacagt gcgctccccg cgttccacca gcaggtccag gttttcataa
    11401 accctgcggt cgccatagga ttggcagact ttttccagct caatgacttt ctgggtgctg
    11461 cgcggaggct gggggaagtt gaatttaaat actttcctgc gggctaccgg tttttgaatg
    11521 attttcatct tttccagctg cttgatgcgg ctctggactt gcccggcttt ggaattgatg
    11581 gagcggaaac ggtcaataaa ttcctgaatg tgcgctattt ccttctgctg gttgcggtag
    11641 gccgcctgaa gctgctcgaa gcgcacgtcc ttttgttgga ggaagtccga gtaattgccg
    11701 cggtattcca ccagttcttc gttgtcgatg tcgtacacgc tttccaccag ctcatccatg
    11761 aaatcccggt cgtgggaaat catcaggatg gctccggggt agtttttcag gtatcgctgg
    11821 agccacagca gggacaggag gtccaggtgg ttggtaggtt cgtccagcat caggaggtcc
    11881 ggctccagga caaggagttt ggccaggtac gcgcgcatga tccagccgcc ggacatttcc
    11941 cgggcggggc ggtggaagtc gctttcccga aaggccagcc ctttgagaat tttcttggct
    12001 ttgggctcca gctggtaacc gttggcggcg ttgaaagtgt caatggcttc cgcgtattcc
    12061 ggcgtatccg ttttgttggc gttttccgcc gtccggatgg tgtggatggc ctgttccatt
    12121 tccggcgtga tgcccagggc gatttccaga acggtttcat ccttcggttc gctggcttcc
    12181 tggggaagat agcccacgat ggcgtattca tccatgctga tggagccttc gtccggcgtg
    12241 tcttctccca gaatcatgcg gaacagggtg gatttgcctg ctccgttggg gccaaccaga
    12301 gccatccgtt ccccccagtt aatggtcatt tccgtttccc tgaacaaggt ccgtccggcg
    12361 tgggattttg tgagattttt gatcgtcagc atggtgaaga gaggatgtat tctaccggga
    12421 tggaaagggg aaggcaagag ccgtcagggc ggaggcaggc atttttgaaa gctttactgg
    12481 atttttacgc gtagtctgct agccttggcg cgccatgccg accacgcaga cattcaggct
    12541 tttgcttgct gccgcccttt tgtgcggatg gagttcctgc tgtactcctc cggcggagga
    12601 ttatatacaa caaacttacg tgcagcagca aatgtccggg ctggctaatg ccttcctggc
    12661 gctgctgccg ccggatcagg cctctcttcc cgctgccgga gcggaggcca ggtggctggc
    12721 ggacacggcc gtggtccagt ccgccgcgat tgcccgggac aacaggactg tgctgtttgg
    12781 ctggctgaac aatattctgg tcaattccaa cctgcgcgac agggggctgt gctggcaggt
    12841 ccagcaggat ttgtaccggg acctgcgccg ccgccccgtg aagtatttcc gcatagggct
    12901 gacgattcga gaccgtggaa cgggccggga gcacagttgc gtgtatgtca atgccgcggg
    12961 gaagggattg cagggctcca ttgttctgga tgcctggaag aactgcgggc atctggtgac
    13021 gctgacccag aaggaccggg aaggcggcaa atgggaggag gactggcggg aaccatttgt
    13081 ttccaaggcc tttccggagg gccattccta cggcatggaa catcacctgg tctggcccgg
    13141 gtgggccagg aaacgcccca ttctggttca gcggatattt cagtccgatc agcagaatga
    13201 ggcgaaggcg gccgctgaat aaaggggaag cctgatccgg caggaaccgg cacacggtgc
    13261 tgcgccgcgg cggtttgcgg tatccgccgt ttttaaggaa aatcccggcg aatcggcaaa
    13321 tggcggaggg aatccggact cagggcaaat aaaaacgcac tcagtgcgta caccgagtgc
    13381 ggattaattg gataatttgc tagtgttgca gggcaaaacc ctgctgcaaa cttacttgcc
    13441 cttggcctgc acaaccggag cgggagcagg agcggtggtt tgctgttgct gctgctgctg
    13501 ggagcaagaa gcgaccaggc aagcggcgcc ggcgatggcg aggatagcga tgttcttcat
    13561 aattcgaatt aaatacagtg tttgttaact actggaacct ccgcatccac ggaggtttgc
    13621 tggcaccaat gtaaatggtg gcaagtagaa atcaagagat tttcttgttc catgtcacgg
    13681 cattacaga
//
