LOCUS       c00020_gnlPro..        13792 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOPLALAH_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:56:15
            Original ID  :: gnl|Prokka|AOPLALAH_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13792
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13792
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[302:3792]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      303..3792
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13792
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13792
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             2..289
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="QEAIPSGHQSNSCNQYFSFSKKDGGRRCRTGACLGFVRHCQVRSP
                     GLLGAFRCNNFLRCATMRKQLSGILFLVQGNLVMKKLPTADAAGSFYRAS"
     CDS             complement(303..1133)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.8e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 5.8e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1111..3069)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.8e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.9e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3091..3792)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3993..4265
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4268..5083
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5117..5350)
                     /locus_tag="ctg20_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5780..6487)
                     /locus_tag="ctg20_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATALLDSSIVGYSDFASQTADFGTR
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6518..6607)
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             complement(7033..7281)
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="VLAVGAAVPPAAYKYVLDVSCIKSITDWLTARKRYVNAASRSRGE
                     PSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             7313..7522
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="LTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7615..7830
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MRDSCPPEGTEFPGAGGRIRFSPHGGNLLETFLRRNTGKLFLYRK
                     MPVKFGSALFVHMVHGSFHIAAFQAG"
     CDS             7972..8157
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MTDVASTMFPDDAAAVDGDCIQLRDEGRTDAHDMEQVMFIAAGDE
                     IVSERFSRDMFRFGMV"
     CDS             complement(8201..8992)
                     /locus_tag="ctg20_14"
                     /transl_table=11
                     /translation="VSISPFWISETEIPWELYTAFMENGRPRAKDGQLLEEQPDDELWD
                     SVTQPTAPYAAMNLGMGHGYEHGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEWEY
                     ACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLD
                     SYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQ
                     NPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKGEP"
     CDS             complement(9430..10203)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_15"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10303..10821)
                     /locus_tag="ctg20_16"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPSAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLAEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10885..12432)
                     /locus_tag="ctg20_17"
                     /transl_table=11
                     /translation="MTINWGERMALVGPNGAGKSTLFRMILGEDTPDEGSISMDEYAIV
                     GYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDTFNAANG
                     YQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDEPTNHLD
                     LLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDFLQQKDV
                     RFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPVARRKVF
                     KFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGKSTLLKI
                     LAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEARSILGS
                     FLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEALVQALKH
                     YEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGGITAE"
     CDS             12618..13325
                     /locus_tag="ctg20_18"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQTYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPILVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 acaggaggcc atcccttccg ggcatcagtc taattcctgt aatcaatatt tttctttctc
       61 gaagaaagat gggggccgtc gctgtcggac gggggcctgc ttaggtttcg tccggcattg
      121 ccaagtacgg tctcctggat tactgggggc cttccggtgt aacaattttt tacgctgcgc
      181 gacgatgagg aagcaactgt ctggtatttt attcctggtt caaggaaatc tggtaatgaa
      241 aaaactcccg acagccgatg ccgccgggag tttttacaga gcgtcttaag aaggaatctt
      301 ctttagaaac agaggccttc cttggcgttg gcccgcatga agtcgcggtt gaggcgggcg
      361 atgttgtcca cgctgatgcc tttcgggcag gcggcttcac attcatactg gttcgtgcag
      421 ttgccgaagc cttccgcttc catctgcttc atcatggcca ggacgcgctt ggaacgttcc
      481 ggctggccct gcggcagcag attgagatgg gcgatcttgg cggaggtgaa cagcatggcg
      541 gaggcgtttt tacaggaggc cacgcaggcg ccgcagccga tgcaggcggc cgcgtcaaag
      601 gcggcgtccg ccttcacttt ttccacggcg atgttgttgg cgttcggcgc ggaaccggta
      661 cgcacgtcaa tatagcctcc ggcggcgatg atgcggtcca gggcggagcg gtccaccatc
      721 aggtcccgca ggattgggaa agccttcgcg cggaagggtt caatccagac ggtatcgccg
      781 tccttgaact tgcgcatgtg aagctggcaa gtggtcacct ggcgttccgg cccgtgggga
      841 atgccgttga tggtcaggga gcacatgccg cagatgcctt cccggcagtc gtggtcaaaa
      901 tggatgggtt ccttgccttc cttgaccagg ccttcattga cgatgtccag catttccagg
      961 aaggaggcgt ccaccggaat gtccttggcg gcataggtct caatgcggcc cttggcttcc
     1021 cggttttcct ggcgccagac cttgagagtg agattgagtg ttttagccat gttataatct
     1081 ttcttttgag tgttaatgta ttggctatct ttacttgtag ctgcggatgg caaggtgcac
     1141 gttctcgaag gtcagcggtt ccttgtggag aacaggcagg ctgtccacgc cagtgtattc
     1201 ccaggcggct acataggcgt attcatcgtc gttgcgcttg gcttcgccgt ccggcagctg
     1261 gtattccacg cggaagtggg cgccgcagga ttcctggcgg ttcagggcgt catagcagag
     1321 cagctgggcg aattccagga agtcggccac gcggcaggct ttttccagtt ccgcgttgat
     1381 gccgtccgcc gtgccggtta cgcgcacgtt ttcccagaat tccttgcgga gctggggaat
     1441 gcgttcaatg gcgtgggtca ggctttcttc cgtgcgggcc atgccgcagt cttcccacat
     1501 gatgaggccc agttcccggt ggaaggagtc caccgtcttg gtgcccttca cattcaggag
     1561 cttgttgatg cgttccttca cttcgtcttc cgcagccttg aattccgggg cggcggtggt
     1621 gacggcgccg ggcttggtgg tcgtcaggta agcgggcagc gtggcgggaa tgacgaagta
     1681 gccgtcagac aggccctgca tcagggcgga ggctcccagg cggttggcgc cgtggtcgga
     1741 gaagttggct tcaccgagga cgtgcaaccc cttcacgttg gacatgaggt tgtagtccac
     1801 ccacaggccg cccatggtgt agtgggaggc ggggtagatc atcatgggcg tttcatgggg
     1861 gtcgtcgtcc gtgatttctt cgtacatgtc aaacagattg ccgtattggc cgtcaatcca
     1921 ttcgcggccc atgcgcttga tttcatccgc aaaatccagg aagacgccct tgccggtgac
     1981 ggccacgccg cggccgtcgt cgcaggcttc cttggcggcg cgggaggaaa tgtcgcgcgg
     2041 agccaggttg ccgaaggagg gatacttgcg ttccaggtag tagtcccgtt cttcttcggg
     2101 aacatcggaa ggcttgattt ccttcttacg gattttttct gcggtttcac gggacttggg
     2161 cacccagatg cggccgctgt tgcggaggga ttccgacatc agcgtcagtt tggactggta
     2221 gtcgcctttg accggaatgc aggtggggtg gatttgcgtg aagcaggggt tggcgaagaa
     2281 ggcaccacgc ttgtaggctt tgtaggcggc agtgacgttg caacccatcg cgttggtgga
     2341 caggaagaac acgttgccgt agccgcccgt gcagagcagg acggtatccc ctgcgtagga
     2401 tttgatttcg ccggtaacca gattgcgggt gacgatgccc ttggcttcgc cgtccaccaa
     2461 caccagatcc atcatttcat ggcgggagaa catttcaatg tgtcccttgg ccacttcctt
     2521 ttccagggcc tggtaggcac ccagcaggag ctgctggccc gtctgtccgc gtgcgtagaa
     2581 ggttcgcttg agctgggcgc cgccgaagga gcggttgtcc agcaggccgc cgtattcacg
     2641 gccgaaggga acgccctggg ccacacactg gtcaatgatg ttggaggaga cttccgccag
     2701 acggtagaca ttggcttcac gggcgcggaa gtcgccgcct ttaacggtgt cgtaaaacag
     2761 gcggtaaacg gagtcgccgt cgttctggta gttcttggcc gcgttaatgc cgccctgggc
     2821 cgcaatggag tgggcgcggc gggggctgtc ctggtagcag aagcatttga cgttgtagcc
     2881 aagttcggca agcgtggcgg cagcggaggc gccagccagg ccggaaccta ccacaagcac
     2941 cgtgtacttg cgcttgttgt tcggattgat cagtttggac tcaagtttgt acttggacca
     3001 tttgtcctga atagggccgg agggaatttt ggcatccggc atccagtcgc ttacgggaaa
     3061 attaatcatg actttgagag gagttgatgg ttatttgatg atacccagaa gaaccgagac
     3121 cggcacggag atgaagccca ggcagataat cgcgccgtag gcgatggcga taaagttgta
     3181 gaagggccgg attttgcggg aatcgacgcc cacagtctgg aagatggact gtaccccgtg
     3241 gcgcagatgg ctgaacagca tcagaacggc caggatgtag aaggcggagc accatacgtt
     3301 ggagaatccg gtcacgatca tcttgtacac gtcaaaggtt tccaccgtac cgtcggaaat
     3361 aaaggtggtg aactgggcgg ggtcgtatcc cacgcgcagg gtgtactggt acaggtggta
     3421 gatcaggaac accaggacgg tcaaaccggt atagatcatg tagcgggagg agagcgttgc
     3481 cttaatggtg ttcttgaaca cgtagggttc gcgggccgca tggttttcca gcttcagctg
     3541 gatggtcagc cagacgtgga tgatgaagat caccgcaagc cccgcgcgga ttccccagag
     3601 ggctgcttcc ggcatggagt gcaggccgtg ggcgtaggtg ttgatccatt cagggcctcc
     3661 gaagatgaga aggttgcctg ccaggtgtcc cgcaaggaac aagaccaaac ataaccccgt
     3721 cagagccaca atgattttgc ggccgatgga ggatgtcacg aatgtacata tggtttttac
     3781 tagtgcattc ataggcgctc taatgaaata aatgcgtctt cacaggatgc ccggttcaag
     3841 cccggatggc aagcctcttc ttgaatttcc ggcgcttttc ggatttttga aaaaccgggg
     3901 aaagaggttg ctgtttatca gtttggaatg gttatcattt tgttgcctgt tccggcttga
     3961 cgaggctttc cgcataggcg tatcgtctgt gcatgaaaag aagtaaaaag gaggtgctgg
     4021 acgcggattt cgcagcggcg cgcgccggcg ttctggatgt ggccgcattt ctggaccggg
     4081 tggaccgcgg ggaaggggag gcggatttcc gctaccatgc cctgatggat gttcttcccc
     4141 tcttgtccgc atccggcccc ggacgcgtcc gggccattct ggaagccctt tcctacaggg
     4201 atgacaccgt gccggaaacc gccgcagcca aagcggcctg cggagccccg aacctcagca
     4261 aataagaatg atggctttca tagaacctca tatacatatg gtgtgccgca ccacggacga
     4321 ataccgggcc atggcgcagg ccggctgcct ggcggtaggg gaaccggcgt tctgggccgg
     4381 ttacgaccgt tcgtccgcgg acggtttccg ggattatttc gtacagctta cggaatgcga
     4441 acccgccagg gcggccaagt tcggcatgga ccattacaca tggctgtgca tcaatcccaa
     4501 ggaggcgcag gacgtggctt tcgcgcggga tgtgatgaaa ctgattccgg agttcattga
     4561 ccggcccaat gtcctcggca tcggggaaat agggctgaac cggaatactt cccatgaaat
     4621 gactattttt gaagagcatc tggatctggc ggtgcgcctc aaccagcttg tgctgattca
     4681 cactccccat ctggaagaca agcttaaggg gaccgtaatg attctttccg ccctgaaaaa
     4741 ccgtccggat ctggaccctt gccgcgtgct ggtggatcac tgtgaggaac ataccttccc
     4801 gctggtgaag gaggccggtt actgggccgg gctgaccctt tatcccacca gcaagctgaa
     4861 tcccaagcgg gcggcggata ttctggaatt gtacggaatg gaccgtgtct gggccaattc
     4921 cgcggcggac tggggggatt ccgatcccct ggcgctgacg gccctggcct gcgagctacg
     4981 caggcgcggt ttttcccggc aggaaacgga acgtcttctc ctggaaaatc cggagacatt
     5041 catgggacag tccccgaagt tccggaaagt gtcgtcccgc taattccgcc cgaggcgcgg
     5101 cggagggtac ggccctctag tccccgtccg ggaaaaagac ggtgaggacg gcgcccagga
     5161 tgaccgccgc gtcatccaga aggcccagcc tgccgattcc gtcaaacagg aattcgtcgg
     5221 gagtcaggat gtaggcgccg gcggcggcca gaaggcatat attccgtttg ttgaaaaaac
     5281 gcggttctcc ttttctgctt ttgaaatacc ggaacaggcg cagtagcagc tgctgttttt
     5341 gaaggttcat ggatgggaac gggggataaa ggttcaagtt cagccatttt cccactcctt
     5401 ttccctgttt cagggaagga gtctgttgcc gacggacgga aaccgcagcg atccggaccg
     5461 tgcggggaaa tggattgctg aaaggatggg ctgttccgga tgctgaggga agccgggctt
     5521 tgcatgctcc ggttccggct gtcccggcat gggaaaaagg ggcgtgtacg gaagtggggc
     5581 ggggccggaa gctcttgaaa tgaccctccc gggggagcct gaatgccatt tccccgtcaa
     5641 gtgctggccg tgagggtacc cagcaaatag aagcttcttc cccctgtttt ttccggcaga
     5701 tgtttgaacg gataaggaaa aggccggctc acgattttgt gagccggcct ttgaatatag
     5761 ggaggcggac ggtacaggct tatgccctgc ggcggcgcat catcagcgcg gccagtccca
     5821 gcaggcccag ggaagccgtg gcgggttccg gaatgctggc gatttcactc atcagctgac
     5881 caacttgttc ctgggaaagg agggagtcgt ggatgtagag ctgttcgatg gattcagcca
     5941 gtcctgcgtc catgagaatc tgattaattt gctggttgcc gaatttcagg ccgctgttgg
     6001 aatagtacgt agcgctgtct ccaaaataga tgcgggtgcc aagatctccg gtgactacgg
     6061 aaatggtcag ggaaccttcc gtgcccagcg gggtgtcaac gacgggcccg ctgtatgagg
     6121 tgttgttcca taatccctgg agtttccggt ccgtgttcag gcccacgccc cagcttacac
     6181 tgctgttttt ggcgttaaac agagcggtat aggtctccgg agtgttgatt ttggacaggt
     6241 caagaaccat cgtcacagac ataacgtcgc ggttgttggc accgtatccg ttgaaggtta
     6301 tcccggacaa cgtcagattg ctgtcgtcag acgtgatgga aacggaatct ttccgggtgc
     6361 cgaaatccgc cgtttgggag gcaaagtccg aatatcccac gatggagcta tccaacagag
     6421 cggtagccgc ggtagcgctc aggctcatgc cggccgaaag aatcagggtg gataataatt
     6481 tattcatggt cagtatctta ataaaatgat tcaaggttca atgtatgtac ttgtgcttga
     6541 ataacgaatt tggaatccgc aagcaattaa aaatattaag agttagtata ttgtatttat
     6601 aattcattga aaataatgat tttttaatat ctctggtcct tttgtcaaga tgacgggtca
     6661 gtctttgtta ttcattggtt tcatgattga tttggcctct ttttcattac ttgacggatt
     6721 ccaaatccga ttggggaatt ccaaattcgc tacaagttgc catccaaaag gaataataaa
     6781 tatgaagaaa acactgacat ttttaatcgc gatgggaagc tttgctgttt cctcggaggc
     6841 agcgaccgtt tttaattatt acactcccgg tacggataat tacaatagta ccatccatgg
     6901 gttttatctt ggcctggggt cttcttccct ggctccttcc gattcctctt ctccctcctc
     6961 cctgtccgga gagatcagac tggacagttt tacgctgcgc ggagccgcca acaatttggg
     7021 cgctaatgtc acttacggct tcctggtgct gaatggctcc gacaattcgg tcatcggctg
     7081 gagcaccaat acgggaacta ctgcagcagg gattaatctg acgttcagtt tttcttccct
     7141 ggatggttct cccctgcttc ttgacgcggc attgacatac cgtttcctgg ccgtgagcca
     7201 gtccgtgatg gacttgatgc aggatacgtc taaaacgtat ttatatgctg cggggggaac
     7261 agccgcccct actgctaaca cggaaggaga taccgtaacg atcagcggcg gattgactgc
     7321 tcccggcatc cgcggccatt atgacgccga gggagcgcct ggtgattctg tcgttattac
     7381 gggagccaac ggaaccaata ctttcagctt attatccccg attttcacgg aaatccgagg
     7441 ggaaatggtg ccggaaccag ccacggtttc cctgggcctg ctgggactgg ccgcgctgat
     7501 gatgcgccgc cgcagggctt gagcttcctg atggcgaaaa atcggcggat gagagctgtt
     7561 cttgcggaac agctcttgtt ttttatatcc agagaggaag aattgcttat ccgtatgcgg
     7621 gattcatgcc ctccggaagg tacggaattt ccgggggcag ggggccgtat ccggttttct
     7681 ccgcatggcg gcaatttgct ggaaacgttt ttgagacgca ataccggaaa gctttttctt
     7741 taccggaaaa tgccggtcaa attcggcagc gcgcttttcg tccatatggt acacggcagc
     7801 ttccacatag cggcctttca ggccggatag ggaacccctt tgcagcgcac agacctggag
     7861 ggccgccgca tacctattat ccgccgtcct attccccggc actggtattc cggaagaacg
     7921 gcaatgggcc ccatgcccag cacttcatat tcttttccat cgtctgccct gatgacggac
     7981 gttgcatcaa cgatgtttcc cgacgatgcg gctgccgtgg acggcgactg catccagctc
     8041 cgggatgaag gaaggactga cgcgcatgat atggagcagg taatgttcat tgcagccggg
     8101 gacgaaatag tttcagaacg cttctctcgt gacatgttcc gtttcggcat ggtctgagga
     8161 ttgttccgtt cttaatgcaa tggtcatgaa agattgttct ttacggctcc cccttggaga
     8221 aattccagag gcggtgcatc gtcataacgt ccggaatgtt catggggcgc accacgcgga
     8281 acccgatcat gcctccgtcc gtcaggtacc agatgctttt agggttttga ggatcctgac
     8341 ggttccaggc gggggtgctg gcgcggcgcg cagcgcttct caggctgtcc gggtcgtctt
     8401 cccacgaacc gccgcgaacg atgtgagggg cgccggggat gatgaccagg gggtctttcg
     8461 cgggcaatcc gctccgtttg ccgtaggcat ccggaacgta agagtccaaa acccattccg
     8521 ccacatttcc gtgcatgtcc cggagtcccc acttatttgg ttttttagag cctgttttct
     8581 ggtagcggtc attggagttg ttccagtacc aggcgtactg gtccagagag gcttccccgt
     8641 ttccgtaaga ataggcgccg ggggagccgg cccggcaggc gtattcccat tccgcctccg
     8701 tgggcaggcg gtagtaatgc ccggtctggg cgctcagcca ttcgcagaat ttgctggcgg
     8761 cgtggtggga catggagatg gcgggcaggc cgtgttcata gccgtggccc atgcccaggt
     8821 tcatggcggc gtagggggcg gtaggctgcg taacggagtc ccacagttcg tcatccggct
     8881 gttcctccag aagctgaccg tccttggcgc gcggacgccc gttttccatg aaggccgtat
     8941 aaagttccca ggggatttcc gtttccgaga tccagaaggg agagatgctc actttatgct
     9001 gcggtccttc gtccggtttc cggtgcggct cttccgcggg actccccatg aggaacgttc
     9061 ctcccggtat ggcaaccatg cgcagggaag ctcccgccgc gggaaccgtt tccgtgtagg
     9121 attcaaaacg tgccggattt ccggaagctt caatgagctg atggatttgg cgcgtcgtgc
     9181 cgaccagctc ccgggacggc aggtcatccg gaatgggaag ggcaggaccg gcagcgcggt
     9241 ccagttcccg tttttgcagc gcggatcggc tttctcccca ctggcgtgcg ctggtaatgc
     9301 gcgcggcatc ttccgtggcc gggcgggggg aattattttc ttcccggcac ccggccagca
     9361 gggcgcttcc tcccagaaag caggaaacaa ggaaaatgcc acgcatggaa tggagaaaac
     9421 cggaatgccc tacatcgtca tgcctccgtc gcaggcaatg acctgcccgg tgatgtaacg
     9481 ggcatcgtca gaggcaagga aggccgtcag ggcggcgata tcttccacgg aaccttgttc
     9541 tttcaaaggt attttcttaa cgatttcttc cttgagattg tcgggaatgg cattggacat
     9601 ttccgtggag atgaagccgg gagcaatggc gttgcacgtg actttgcgcg gagcgaattc
     9661 ctgtgccagt gatttggtga aaccgatgag gcccgccttg gaagcggcgt aattggcctg
     9721 gccgatgttg ccgacgagac cgatgacgga gctcatgttg atgatgcgcc cggccgggga
     9781 tttcatgaga acgcgctgga gggccttgac cgtattgaac gcgcttttca ggttggtgtc
     9841 cagaacggca tcccagtctt cctctttcat gcggagcatc agggagtccc gcgtgatgcc
     9901 ggcgttgttc accaggatgt caatctgcgg gaagtctttc aaaatggcgg ccatggtttc
     9961 ctgaacggcc gcgtaatccg ctacgtcgca ggggtaggcc ttgcaggaat ccggaaattc
    10021 cttgttgatt tcttctgcgg cccccccgca gctggatgga ctgcggctga tcaggatgac
    10081 cctggctcct tccgaagcga agcggcgcgc gacggcattg ccgattccgc ggcccgcgcc
    10141 ggtaacgatg gctgttttac ctgctaactt ttgcatgctg cccacagtaa acccgttttt
    10201 cacggttccg gcaagcttga aatggacttg gccgcgcagg aacccatacg gggaaagggc
    10261 gtgccgggaa tgaaaaaaga ggggggagaa acggggcggg ggctactgtc cggcctcttc
    10321 attttcccgg agtgcaccgg ggggcgcccc gtcttcatcc ggttctgcca ggtcgctgaa
    10381 ttcatccgaa ttttccaaaa tgtcctttaa ggcggcggaa ccgtaatagc gggcctcaaa
    10441 caggcgtttg ccttcctgcc tgcagcggtt gtccagcatt tccattcgtt tttccatttt
    10501 ttctatcaag gcgtcttctt tctccttttc cgcatcgttc aatttatcct gaagctggag
    10561 gaaatgccgg atgtccttct gaatgtcctg cagcgttttg acggcgttgt ccgcgctttc
    10621 cttgtcctga acgcctgcca acgtctgctg gatattgatg gcaaaggaaa aggcctggtt
    10681 gatcagggat tccgcggaag gaattttttc cgccggagcc gctgctgagg gggaagccgt
    10741 tccggcggcc gtttcaccaa atgcaagaga ggctccggac agaagcgcag aatataagag
    10801 aggaacaaga aaagccttca tcctgttctt ttaaggcagg atgaaatcca cggcaaggaa
    10861 aaaggggaaa ctgaaaaaag agccttattc cgccgtgatg ccgccttttt catcgtccag
    10921 aatgcctgac ttttccagat aatagtcata tccgcctgcg taggcggtga tggtcccccg
    10981 gttcacatgc agggtttttt gtgccaggga acggatgaag tgcacatcgt gggagatgaa
    11041 gaccagtgtt ccttcataat gcttcagagc ctgcaccagg gcttctacgg acaaaaggtc
    11101 caggtgggtg gtcggctcgt ccatcagcag gaggttgggc ggatccacca ggaatttgac
    11161 caggctgagc cgcgattttt ccccgccgga aagaacgctg acgcgttttt ccacatccag
    11221 cctccggaac aggaaggaac ccaggatgga acgcgcttct tcctcccgga tttcagcgct
    11281 gcatttcatg atttcctcca gcacggtatt ttccggattc aggttttccg ttcgcgcctg
    11341 ggagaagtag ccgatgcgcg tcgtggtacc gggagtgcgt tgtccggagt caatggggat
    11401 gatgcccgcc aggattttga gaagagtgga tttgcctgcg ccgttcgggc ctacaagaac
    11461 agtgcgctcc ccgcgttcca ccagcaggtc caggttttca taaaccctgc ggtcgccata
    11521 ggattggcag actttttcca gctcaatgac tttctgggtg ctgcgcggag gctgggggaa
    11581 gttgaattta aatactttcc tgcgggctac cggtttttga atgattttca tcttttccag
    11641 ctgcttgatg cggctctgga cttgcccggc tttggaattg atggagcgga aacggtcaat
    11701 aaattcctga atgtgcgcta tttccttctg ctggttgcgg taggccgcct gaagctgctc
    11761 gaagcgcacg tccttttgtt ggaggaagtc cgagtaattg ccgcggtatt ccaccagttc
    11821 ttcgttgtcg atgtcgtaca cgctttccac cagctcatcc atgaaatccc ggtcgtggga
    11881 aatcatcagg atggctccgg ggtagttttt caggtatcgc tggagccaca gcagggacag
    11941 gaggtccagg tggttggtag gttcgtccag catcaggagg tccggctcca ggacaaggag
    12001 tttggccagg tacgcgcgca tgatccagcc gccggacatt tcccgggcgg ggcggtggaa
    12061 gtcgctttcc cgaaaggcca gccctttgag aattttcttg gctttgggct ccagctggta
    12121 accgttggcg gcgttgaaag tgtcaatggc ttccgcgtat tccggcgtat ccgttttgtt
    12181 ggcgttttcc gccgtccgga tggtgtggat ggcctgttcc atttccggcg tgatgcccag
    12241 ggcgatttcc agaacggttt catccttcgg ttcgctggct tcctggggaa gatagcccac
    12301 gatggcgtat tcatccatgc tgatggagcc ttcgtccggc gtgtcttctc ccagaatcat
    12361 gcggaacagg gtggatttgc ctgctccgtt ggggccaacc agagccatcc gttcccccca
    12421 gttaatggtc atttccgttt ccctgaacaa ggtccgtccg gcgtgggatt ttgtgagatt
    12481 tttgatcgtc agcatggtga agagaggatg tattctaccg ggatggaaag gggaaggcaa
    12541 gagccgtcag ggcggaggca ggcatttttg aaagctttac tggattttta cgcgtagtct
    12601 gctagccttg gcgcgccatg ccgaccacgc agacattcag gcttttgctt gctgccgccc
    12661 ttttgtgcgg atggagttcc tgctgtactc ctccggcgga ggattatata caacaaactt
    12721 acgtgcagca gcaaatgtcc gggctggcta atgccttcct ggcgctgctg ccgccggatc
    12781 aggcctctct tcccgctgcc ggagcggagg ccaggtggct ggcggacacg gccgtggtcc
    12841 agtccgccgc gattgcccgg gacaacagga ctgtgctgtt tggctggctg aacaatattc
    12901 tggtcaattc caacctgcgc gacagggggc tgtgctggca ggtccagcag gatttgtacc
    12961 gggacctgcg ccgccgcccc gtgaagtatt tccgcatagg gctgacgatt cgagaccgtg
    13021 gaacgggccg ggagcacagt tgcgtgtatg tcaatgccgc ggggaaggga ttgcagggct
    13081 ccattgttct ggatgcctgg aagaactgcg ggcatctggt gacgctgacc cagaaggacc
    13141 gggaaggcgg caaatgggag gaggactggc gggaaccatt tgtttccaag gcctttccgg
    13201 agggccattc ctacggcatg gaacatcacc tggtctggcc cgggtgggcc aggaaacgcc
    13261 ccattctggt tcagcggata tttcagtccg atcagcagaa tgaggcgaag gcggccgctg
    13321 aataaagggg aagcctgatc cggcaggaac cggcacacgg tgctgcgccg cggcggtttg
    13381 cggtatccgc cgtttttaag gaaaatcccg gcgaatcggc aaatggcgga gggaatccgg
    13441 actcagggca aataaaaacg cactcagtgc gtacaccgag tgcggattaa ttggataatt
    13501 tgctagtgtt gcagggcaaa accctgctgc aaacttactt gcccttggcc tgcacaaccg
    13561 gagcgggagc aggagcggtg gtttgctgtt gctgctgctg ctgggagcaa gaagcgacca
    13621 ggcaagcggc gccggcgatg gcgaggatag cgatgttctt cataattcga attaaataca
    13681 gtgtttgtta actactggaa cctccgcatc cacggaggtt tgctggcacc aatgtaaatg
    13741 gtggcaagta gaaatcaaga gattttcttg ttccatgtca cggcattaca ga
//
