LOCUS       c00014_gnlPro..        13701 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HGILLCGL_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:47:58
            Original ID  :: gnl|Prokka|HGILLCGL_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 28651
            Orig. end    :: 42352
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13701
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[38651:41624]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..13701
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13701
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             519..2378
                     /locus_tag="ctg14_25"
                     /transl_table=11
                     /translation="MRKAIIMLSLFLCHFTLVYGNNQGKQEYILVLNSVNYDEVWTNGV
                     YQSIYNTFNGSQYAIRTEELMVPTIANADEAEAKRNSLLEKYPIRPKVVVFIGDPGWIV
                     YRSLFDSEWKEVPVLICYSRKTMPGCIENLLSRNISDKELVPASQMLKGYNITTLYQPF
                     YMKETIELMQRIQPEIKNIAFISDNRYISLCAQKEVEQAMADYYPSLKLDILTTTRLST
                     EQLLDTISRYNKETGILYYSWFSKQVQENNYLNDNIQRIVYGFAHNPVFTVADLQAENG
                     NFAGGHYISLPDFSEEVIHTLQQIVDGTPARDIQPHNGGEPQTYLNYRHLKLHNTDSNL
                     YPRNAVYYQRPPSFYEQNKLAIICIIALACAIVIILVMRLRFYWQVQQEIREREKAEEA
                     NRLKSAFLANMSHEIRTPLNAIIGFSTLLANEENLEERQEFIKIIENNNELLLQLINDI
                     LDLSKIEAGTLEFIYSDVDVNSLLTEIEQSSRIRNRHPEIQISFEERLPQCIIHTERNR
                     LTQVINNLLTNSMKFTTLGSIRFGYRQEGNRLRFYVKDTGCGIPADKIDSVFGRFVKLN
                     NFQQGTGLGLSICKTIVEKLGGEIGVESKEGVGTLFWFTIKVE"
     CDS             2483..3742
                     /locus_tag="ctg14_26"
                     /transl_table=11
                     /translation="MKRNLLLLAAICSCYNLFAEEVIVKQFRYAGPYEVKKPFLKDSLD
                     VNSKKFTEKELLKTAVPFSNVRQSTQLLEANADGESTLPAGNQSSYIGLASFYLNSDRY
                     VKGTLQVKGPETYEVYVNNEKQTAPDGKVSLSLEPHRYEIVIKYLAESDKAETLKVSFD
                     TEKEAVITATTDPEKRYTISDVFDGTRFRSVSLSPNGKYLLTSYQTTYPGGQTAYFQQI
                     TDNTNGQVLIESSTNNFNWMPQSNRLYYTRKGLQGKELVTVDPVTKAETILSQNLPDGW
                     FSIAPTEDFLIFTISEKGPEKDKDMEEILVPDDRQPGWRNRSFLHKYDLATGVLERLTY
                     GHNSTSLNDISKDGRYLLFTSSRRELTKRPFSTKILYRMDLQNRQVDTLLEDPFINYAS
                     FSPDGKQLAVSGXXXXGRSI"
     CDS             3753..4979
                     /locus_tag="ctg14_27"
                     /transl_table=11
                     /translation="LNIAPGQTSNLADGQLFIYDLSNKQATAVSKDFNPSIQSFTWNTG
                     DKQIYLQGEDKDCVRLYTLNPANGKISPVPLKEDILSDFTIAENTPELVYFGESASNSQ
                     RLYSMNLKKKEKESVCLKDLSKDILKDITLGEVHDWNFQAAAGDTIYGRYYLPPHFDPS
                     KKYPLIVNYYGGTSPTERSLENRYPSHTYAALGYVVYIIQPSGATGFGQEFSARHVNAW
                     GKRTGDEIIEGTKKFCEEHSFVDAKKIGCIGASYGGFMTQYLQTKTDIFAAAISHAGIS
                     DITSYWGEGYWGYSYSALATANSYPWNARDIYVEQSPLFHADKINTPILFLHGSVDTNV
                     PVGESIQMFTALKLLGKPTAFIQVNGQNHQILDYKKRAEWNKTIYAWFAKYLKEQPEWW
                     EALYPPKSL"
     CDS             complement(5151..6509)
                     /locus_tag="ctg14_28"
                     /transl_table=11
                     /translation="MSMHEIESLVESSVITVATASPIPPLARNICFNLYQLQNQLDCGY
                     TVLRVREELEKLGYLFLLPPEQLPEPERSAALKLNEKGGFLSDGTYFDHRSGRCCVTAG
                     SLLWTKLIDLGILPESAKTELRELDPLELAELIIPLASKVLAGGDKEDDNYANAADTLG
                     FWYAFFPLFCQMAGMDEEDAPEPERIRALLEMLAVPESFEVLATDEIGKELDDFEEEEM
                     PFLSGWSAPYNEWKNKNNTGDLSLEFCKSMVHDSILKRKFVEADRYASAMEEGPELNRL
                     FHRCLVGMSYYEWVKIQGIKIPIIESVLSQEEAKEGFERVADLSVSSDNVQCARLGIFR
                     ILALQGEYAESVEYLNAVYFKALDECGQKSKELLGQSQRAVLVVVYYRMLEMSIPDSFP
                     GKKELMAHKALNGSDLRKSREILSLLLIEKSEHAYAWQQAFSFCDELIKKYGF"
     CDS             complement(6634..8184)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_29"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.9e-47, bitscore:
                     151.5, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSSMRNQLSGIFSGLTNEYIFDIQVSPEHESRKELLELLNDVA
                     SCSDKITVQVADGEGLEFSLLKNGEKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNIPD
                     ESICNRVKALNGPVKLTTYVSLTCTNCPDVVQALNAMATLNPEISHEMVDGAINQEEVA
                     AMKVQGVPSVFADGKLIHVGRGDFGELLGKLEAQYGVKEENLSVVEKNYDVIIVGGGPA
                     GSAAAIYTARKGLAVAVVADRIGGQVKETVGIENMISVSQTTGQQLALDLMSHMKDYPI
                     DILEHRRIEKVEVEGREKLLTTSTGEKLIAPAVIVATGASWRRLNVPGESEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGVEAAIDLAGICSKVTLLEFADELKADQVLQDKARSL
                     PNVEIFMHSQTMEVLGNGEKVTGIRIKDRKTEEVRNIELDGIFVQIGLAANSGPFREVV
                     DTNRQGEIVIDSHCRTSVPGIYAAGDVSTVPYKQIIISMGEGAKAALTAFEDRMRGML"
     CDS             complement(8278..8844)
                     /locus_tag="ctg14_30"
                     /transl_table=11
                     /translation="MEPIINSQAPEFKVQAYHNGSFKTVSSDDIKGKWAIFFFYPADFT
                     FVCPTELVDMADKYDQFQAMGVEVYSVSTDSHFVHKAWHDASETIRKIKYPMLADPTGV
                     LSRAFGVMIEEDGMAYRGTFLVNPEGKIKLAEINDNGIGRNADELLRKVEAAQFIAEHP
                     SEVCPAKWKKGGETLKPSIDLVGKI"
     CDS             complement(9005..9484)
                     /locus_tag="ctg14_31"
                     /transl_table=11
                     /translation="MKDKDKDLNVKGAYLHMAADALVSVGVVVSGIVIAHTGWYIIDPI
                     IGLLIAIVIIVSTWGLLRDSIRLSLDGVPAGTDIDKVEKTIHSVEGVEGVHHLHIWAIS
                     TTETALTAHVSVADISEMERIKQEIKHDLQHVGIQHATLEFETSGFKCDGHCCSD"
     CDS             complement(9508..9921)
                     /locus_tag="ctg14_32"
                     /transl_table=11
                     /translation="MNMEQHHHDHHHHEITSLNKAFIIGISLNLAFVVAEFTAGFWYNS
                     LGLLSDAGHNLGDVASLVLAMLAFRLAKVHPTCSYTYGYKKSTVLVSLLNAVILLVAVG
                     IIIAESIGKLLHPRPVEGDAIAWVAGIGVXXXX"
     CDS             complement(10001..10732)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.3;
                     E-value: 1.6e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_33"
                     /sec_met_domain="Radical_SAM (E-value: 3.3e-36, bitscore:
                     116.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LEIKGNIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWDS
                     KGLAKYQMTPEELLAEVLRYKNFIAKGGVTVTGGEPLLQAEFLREFFRLCREAGIHTAL
                     DTSGYICTPKALAVLEYADLVLLDIKTIDPDLHPRLTAVKLDNTLRFLDELEKRGVPVW
                     IRHVIVPGLTDNDEALDKLAEYISHYTVVQKAELLPYHTMGAYKYEAQGLDYKLKEVEP
                     LSAERLANAKEIFKKHGITIW"
     CDS             complement(10740..11561)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_34"
                     /sec_met_domain="Gly_radical (E-value: 1.6e-45, bitscore:
                     145.3, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 9.2e-55, bitscore:
                     177.4, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWLAKVYVNALKIIHYMHDKYAYEAFEMALHDGSVERIRATGIA
                     GLSIVADSLAAIRDTKVKVIRDERGLAVGFEREGDYVPFGNNDDRTDSIAVDITEKFME
                     YLRQHQTYRNATPTQSILTITSNVVYGKKTGATPDGREGGTPFAPGANPMNGRDTKGAV
                     AALASVAKLPFQHAHDGISYTFAVSPATLGKERDIQIANMVGLLDGYFTPDGGQHLNVN
                     VFDKELLLDAMEHPENYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             complement(11582..12973)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_35"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.9e-217, bitscore:
                     714.6, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENENWAQFKGEIWKREINVRDFIQNNYKPYEGDDSFLKDSSD
                     KTKKVWDKLTEMFKVEREKGVYDAETKYPQGIDTYGPGYIDKENEVIVGLQTDAPLKRG
                     IYPKCGTRMVENSLEAYGYKLDPMTKEIFTKYRKTHNEGVFSAYTDEMLAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTEILIAEKKHYLKRLDIQELTEEIIQSREEISEQIKAL
                     KAFEKMCAGYGFDVTKPAKDAREAVQFVYLGYLAAVKDQDGAAMSLGRTSTFLDIYIEK
                     DIREGKLTEEEAQELIDQFIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTKTSYRYLHTLYNLGPAPEPNLTVLWFNNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQYFGARANLAKCLLYAINGGRDQVYRWLRGLNRSPANT
                     WITTK"
     CDS             complement(13584..13700)
                     /locus_tag="ctg14_36"
                     /transl_table=11
                     /translation="ELVLHIYRYCLCLSVVLPLPYQLSFTISINRPDQNPIC"
ORIGIN
        1 tacgatttca aaggtggtcc tgaaatgacg gacggcctga ccggtgatac aaattacaaa
       61 accggccgtt ggctgggctt ccagggaaaa gacctggatg cggcgatcga cctgaaacag
      121 ccggtcgaaa tcagcaaggt ggctttcaat accaatgtgg ttaaaggcga ctggatcatg
      181 ggggctgccg gagttaccgt aaaggtatcc gaagacggta agaacttcag ggaagtggta
      241 tccaaaacaa tcccgtccct gaaacaaacc gataaggatg gcatctatcc gcaggaaatt
      301 accttcgatc cggtaaaagc ccgttacgtg gaagtgataa tcaaaagtga caaactgccg
      361 gcatggcatg gcggcgcagg taatccggcc tatctgttcg tagacgaaat tattattcaa
      421 tagggtaaaa catcaacatt aaagccgtct aaaagactta cctctttccg acagtaagtc
      481 tttcagacgg cttttttact tcaaattata caggctttat gcgaaaagca atcatcatgc
      541 taagcctttt cctctgccat ttcacactag tatacggtaa taatcaaggc aagcaggaat
      601 acatccttgt tctgaactcc gttaattacg acgaagtctg gacgaacgga gtctatcaat
      661 ctatctacaa cacctttaat ggctcgcaat atgcaatccg cacagaagaa ctgatggttc
      721 ctaccatcgc gaacgcggat gaagccgaag ccaaaagaaa ctccttactg gaaaaatatc
      781 ccatacgccc caaagtagtt gtctttatag gcgatcccgg atggatagta taccgttcct
      841 tattcgacag cgaatggaaa gaggtccctg tcttaatctg ctattcacgc aaaaccatgc
      901 caggttgcat cgaaaatctt ctttcccgga atatatcgga caaagaactt gtccctgcca
      961 gccagatgtt gaaaggctat aatataacaa ccttatatca acctttctat atgaaagaga
     1021 cgattgaact catgcaacgt attcaaccgg agataaaaaa tattgctttc atatccgata
     1081 atcgctatat cagcctgtgt gcacaaaaag aagtggaaca agcaatggct gactattatc
     1141 cgtccctgaa gttagatatt ctcactacaa cccggctttc aactgaacag ttgctggaca
     1201 caatatcacg ttacaataaa gaaaccggaa tattgtatta ctcctggttc tctaaacagg
     1261 ttcaagaaaa taattacctg aatgacaaca tacaacgaat cgtttacggc tttgcccata
     1321 atccggtatt taccgttgcc gacctacaag cggaaaacgg gaactttgct ggaggtcatt
     1381 atatctcgct acccgacttt agcgaggagg ttattcatac tttacagcaa atagtagacg
     1441 gcactccggc tcgtgatatc cagccgcaca acggaggtga accacaaacc tacctgaact
     1501 accggcattt gaaactacat aataccgaca gcaatctcta tcctcgcaat gcggtctatt
     1561 atcagcgtcc tccgagtttc tatgaacaga acaaactggc tattatctgt atcatcgcac
     1621 ttgcttgtgc catagtcata atcctggtga tgagactccg gttttactgg caagtacaac
     1681 aggaaatacg cgaacgcgaa aaagccgaag aagccaaccg ccttaaatca gccttcctgg
     1741 caaacatgag ccatgagata cgcaccccgc tgaatgcgat catcggcttc tccaccctgt
     1801 tagccaatga agaaaatctg gaagaaaggc aagaattcat caagatcatc gagaacaaca
     1861 atgagttatt gctccaactg atcaacgaca tactggacct ctccaaaatt gaggcaggaa
     1921 ccctggagtt catctactcg gacgtagacg tgaattcttt actgacggag atagaacaaa
     1981 gcagccgcat ccgtaaccgg catccggaaa tccaaatctc tttcgaagaa cgtctgccac
     2041 aatgcatcat ccatacggaa cgaaaccgcc tgacccaggt cataaacaac ctgctgacca
     2101 actctatgaa gtttacaacc ctgggaagta tccgcttcgg ttatcgacag gaaggcaaca
     2161 ggctgcgttt ctatgtaaaa gacaccggat gcggcatccc tgcggataag atagattcag
     2221 tcttcggacg tttcgtcaaa ctgaacaact tccagcaagg gaccggcctc ggcctctcca
     2281 tctgcaaaac catcgtagaa aagctcggcg gagagatagg tgtcgagtcg aaagaagggg
     2341 tagggacttt attctggttt actattaagg ttgaataaag ttcttctttc atttcttaca
     2401 atacatttca ggatttcaaa agtataggtc tccctgtcaa aaaaataaat acctttgcag
     2461 gaaacatcaa attttattcg ccatgaaaag aaacctattg cttctggcag ctatctgttc
     2521 ctgctataac cttttcgctg aggaggtcat agtcaagcaa ttcagatatg ccggcccgta
     2581 tgaagtgaaa aagccgttcc tgaaagacag cctcgacgta aacagtaaga aattcaccga
     2641 aaaagaatta ttgaaaacag ccgttccgtt tagcaatgta cgtcaaagta cacaattgct
     2701 ggaagcaaat gccgacggag aaagtacact tccggccggc aaccagtctt cttatatcgg
     2761 actggcctct ttctatctga acagcgaccg gtatgtaaaa gggactttgc aggttaaagg
     2821 cccggaaaca tacgaggtct atgtaaataa cgaaaaacaa acagcccccg acggaaaggt
     2881 ttccctgtca ctggaacctc atcgttacga aatcgttatc aaatatttag ccgaaagcga
     2941 taaagccgaa accctgaaag tttcgttcga tacggaaaaa gaggctgtta tcacggctac
     3001 caccgatccg gaaaaaagat atacgatcag cgacgtgttc gacggaacac gtttccgctc
     3061 cgtcagcctc tcccccaacg gaaaatatct gcttacctcc tatcagacta cttatcccgg
     3121 cggacagacc gcatattttc agcagattac cgataatacc aacggacagg tgctgataga
     3181 aagcagtacg aacaatttca actggatgcc ccaaagcaac cgtctttatt atacccgtaa
     3241 aggattacag ggaaaagaac tggtgaccgt cgatccggtg acaaaagccg aaacaatcct
     3301 ctcccaaaat ttacccgatg gctggttcag catcgccccg acagaagatt tcctaatctt
     3361 cacgatctcc gagaaagggc cggaaaaaga caaagacatg gaagaaatcc tcgtgcccga
     3421 cgaccgtcag ccgggatggc gtaaccgttc cttcctccac aaatatgacc tggcaacggg
     3481 tgttctcgaa cgcctcactt acggccacaa ttccacttcg cttaacgaca tttcgaaaga
     3541 tggccgttat ctgctgttca ccagcagccg gcgcgaactg acgaagcgtc cgttcagcac
     3601 aaaaatcctt taccggatgg atttgcagaa caggcaggtt gatacactcc tggaagatcc
     3661 gttcatcaac tatgccagtt tttcaccgga cggaaagcaa ctggctgttt ccggttnnnn
     3721 nnnnnncggg agaagcattt aacaagattg gcttgaatat tgctccggga caaacatcca
     3781 acctggctga cggacagttg ttcatctacg acctctccaa taagcaggcg acagccgtaa
     3841 gcaaggattt taatccgtct atccaatcat ttacatggaa taccggagat aaacaaatct
     3901 acctgcaagg agaagacaaa gactgtgtcc gcctgtatac gctcaaccca gcaaacggaa
     3961 agatcagtcc ggttccactg aaagaagata tattatcgga tttcacaatt gctgaaaata
     4021 cccccgaact tgtttatttc ggcgaaagtg cctccaactc acaacgactc tactccatga
     4081 atctgaaaaa gaaagagaaa gagtctgttt gcctgaaaga cttgtccaaa gacattctga
     4141 aagatattac cctgggcgaa gtacacgact ggaatttcca ggcggctgcc ggagatacca
     4201 tctacggacg ttactatctg ccgccgcatt tcgacccaag caagaaatat ccgctgatcg
     4261 ttaattatta cggcgggaca agtccgacgg aacgctcact cgaaaaccgt tatccgtcgc
     4321 atacctatgc tgcactggga tatgtggttt atatcataca acccagcggt gccaccggtt
     4381 tcggacagga attttccgca cgccacgtca atgcctgggg aaaacgtacg ggagacgaga
     4441 tcatcgaagg aacaaaaaag ttttgtgaag aacacagttt cgtggatgcc aaaaagatcg
     4501 gctgcatcgg cgcctcttac ggcggcttta tgacacagta cctgcaaact aaaaccgata
     4561 tcttcgccgc cgccatctca catgccggta tcagcgatat taccagttat tggggagaag
     4621 gttactgggg atattcttac agtgcactgg ctaccgccaa cagttacccc tggaatgcac
     4681 gggatatcta tgtagaacaa agccccttgt tccatgccga caagatcaac acgccgatcc
     4741 tgttcctgca cggctccgtc gatacaaacg tacctgtagg agaaagtatc cagatgttca
     4801 ctgccctgaa actactcggc aagccgacag ccttcataca ggtaaacgga caaaatcatc
     4861 agatactgga ttataagaaa cgggcggaat ggaacaaaac catctatgcc tggttcgcca
     4921 aatatctgaa agagcagccg gaatggtggg aagctctcta tccgccaaaa agtctgtaaa
     4981 agaattgcgt cgggatgcga cgcaacgtta catcgacatg cagtgcaacg ttacatcgac
     5041 agctgatgta acgttacatt gacagctgat gcaacgttac attgacagct gatgcaacgt
     5101 tacatcgaac cccgatgcaa ataacacata tttcatcagc actaacgatt tcagaatcca
     5161 tactttttta tcagctcatc acaaaaagag aaggcctgtt gccatgcata ggcatgttcg
     5221 gatttttcaa taagcaataa actgagtatt tcccgggatt tgcgaagatc agaaccgttc
     5281 aatgctttat gagccatcag ttcctttttc ccaggaaaac tatcgggtat agacatttcc
     5341 agcatccgat aatagactac cactaacaca gcacgttgcg attgccccag tagttctttc
     5401 gatttttgac cacactcatc gagtgcctta aaatatacgg cattcaaata ctcaaccgat
     5461 tcggcatatt caccctgtaa agcaaggatt ctgaaaatac ccagtcgggc acactgcaca
     5521 ttatcagatg ataccgacaa gtctgctaca cgttcaaaac cttcttttgc ctcttcctga
     5581 gagagaacac tttctataat cgggattttt attccttgta ttttcaccca ttcatagtaa
     5641 gacatgccaa ccaaacaacg atggaaaagc cggttaagtt ctggtccttc ttccatagcg
     5701 gacgcatagc gatcggcctc aacaaacttt ctcttcaaaa tagaatcgtg gaccatcgat
     5761 ttgcaaaact ccagggataa atcccctgta ttgttcttgt tcttccattc attatacgga
     5821 gcgctccaac cggagagaaa aggcatttct tcttcttcaa agtcatccaa ctccttgcca
     5881 atctcatcag tcgcaagtac ttcaaatgat tcgggaacag ccagcatttc aagtaacgcc
     5941 cggattcgct ccggttccgg cgcatcctcc tcgtccatcc ccgccatctg acagaataag
     6001 gggaaaaagg cataccaaaa tcccagcgta tcagcggcat tagcataatt atcatcttct
     6061 ttatctcccc cggcgagcac ctttgaagcc agtgggatga taagttcggc cagttccaaa
     6121 ggatcgagtt cacgaagttc ggtctttgcc gattccggaa ggatgccgag atcgatcagt
     6181 ttcgtccaca gcaacgatcc tgcggtgaca cagcaacgac ccgaacggtg gtcgaaataa
     6241 gttccgtcac tcaaaaagcc acctttttcg ttgagtttca gggctgcact acgttccggc
     6301 tcgggtaatt gctccggagg cagaaggaag agataaccga gtttttccag ttcttcccgt
     6361 acccgcagga cagtatatcc acaatccagt tgattctgga gctggtaaag attgaaacaa
     6421 atgtttcggg ctaaaggagg gataggagaa gcggtggcaa ctgttatcac agaactttcc
     6481 accagacttt caatttcatg catcgacata attgtataga ttagaatgaa tcttgcaaag
     6541 atagcaatac ccggatataa accgacatag aaacgcttct gaatcgattt atacccgggt
     6601 attattttta tgccttccgg aaagttctgc ggcttataac attccccgca tccggtcttc
     6661 gaaagctgtc agggctgctt tggccccttc gcccatcgaa ataatgatct gcttataagg
     6721 gacagtcgat acgtcgccgg ccgcatagat acctggaacg cttgtacgac aatggctatc
     6781 gatcacgatc tcaccctgac ggttcgtatc taccacctca cggaacggac cgctgttggc
     6841 tgccaggccg atctggacaa agatgccatc cagttcgatg ttgcggactt cttctgtctt
     6901 acggtccttt atacggatac cggtcacttt ttcaccgtta cccagtacct ccatcgtctg
     6961 ggaatgcata aagatctcca cgttcggaag gcttcttgcc ttatcctgca agacctgatc
     7021 cgctttcaac tcatcggcaa attcgagaag cgtcactttt gaacagatac cagccaggtc
     7081 gatagccgcc tcaacgcctg aatttcctcc gccaacaaca gccacatgct tgcctttata
     7141 gaacggaccg tcgcaatgcg gacagaaagc gacaccgcgt ccgatatatt cggattctcc
     7201 ggggacattc aacctacgcc agctggctcc ggttgctacg ataacggccg gggctatcag
     7261 tttttcgccg gtagaggttg tcagcagctt ttcgcgtcct tcgacttcca ccttctcgat
     7321 acggcggtgt tcaaggatat cgatcggata atctttcata tgcgacatca ggtcgagagc
     7381 cagctgctgc cccgtcgtct gcgaaacaga aatcatattc tcgataccga cagtttcctt
     7441 cacctgtccg ccgatacggt cggccacaac agccaccgcc aaacctttac gggcagtata
     7501 gatagctgcc gcacttccgg caggacctcc gccgacgatg ataacatcgt agttcttttc
     7561 taccaccgac aggttctcct ctttcacgcc atactgcgct tcgagtttgc caagcagttc
     7621 gccaaagtct ccacgaccta catggatcag tttaccgtcg gcaaatacgg aaggtactcc
     7681 ctgcactttc atggcagcaa cctcttcctg gttgatcgca ccgtccacca tttcgtgaga
     7741 gatttccggg ttcagtgtag ccatggcatt caaagcctgt acaacgtcag gacagttggt
     7801 acaggtcaaa gaaacatatg tagtcagttt gaccgggcca ttcagggcct tcacacggtt
     7861 acaaatactt tcgtcgggaa tatttttgcc tttgccgtca ctgttcagga tagccagcag
     7921 caacgaagta aattcgtgtc cgttgggaac gccccggaat ttaataccgg ttttttcccc
     7981 gtttttcagc agggagaact ccaggccttc gccgtctgcc acctgtacgg tgatcttatc
     8041 ggaacaggaa gccacatcgt tcagcaattc caatagttcc ttcctgcttt catgttcagg
     8101 agaaacttgt atatcaaata tatattcgtt cgtcaatccg ctaaagatac cggacaactg
     8161 atttctcatt gatgaatcta acatagttga atcctttatt ttaattatga atagaacaac
     8221 tgatatttgt ttagataaaa aaggccgaca atatgttgcc ggcctccagt tttactatta
     8281 gatcttaccg accagatcga tgctcggttt caatgtttcg ccaccttttt tccatttggc
     8341 ggggcaaact tcgctcggat gttcggcgat gaactgggca gcttctactt tacgaagcag
     8401 ttcgtcggcg ttacggccga taccgttatc gttgatttct gccagtttga tctttccttc
     8461 cggatttacc aggaatgtac cgcggtaagc cataccgtct tcttcgatca ttacaccgaa
     8521 tgcacggctc aatacgcctg tcgggtctgc caacatcggg tatttgatct tacgaatcgt
     8581 ttcagatgca tcgtgccatg ctttgtgtac gaagtgtgaa tctgtactta cagaataaac
     8641 ttctacaccc attgcctgga actggtcata tttgtcagcc atatctacca actcggtcgg
     8701 acaaacaaat gtaaagtcag ccgggtagaa aaagaaaatc gcccatttgc ctttgatgtc
     8761 gtcgctgctt acagttttga aactaccgtt gtggtatgcc tgaactttaa actcgggtgc
     8821 ttgtgaattg ataataggtt ccatagaatt tttattttaa tcgttattac tattttgttt
     8881 ttgttactgg tgcaaagata agttgccgat tcgaggtaag aacaaaaaat ccaatcgaaa
     8941 ggttttatgc agtcatagac aaaatctttg agtatcagta aatcaggttt ataatatacc
     9001 tgtttcagtc tgagcaacag tgcccatcgc acttgaatcc cgacgtttca aattcgagcg
     9061 tagcatgctg gattcccaca tgctgaaggt cgtgttttat ctcctgtttg atacgttcca
     9121 tttctgaaat atccgcaacg gaaacatggg cggtaagtgc cgtttcggtc gtactgatcg
     9181 cccagatatg aagatggtgg acaccttcga cgccttcaac cgaatgtatc gtcttttcca
     9241 ccttatcgat gtccgttccc gccggcacac cgtccagaga gagacggata ctgtcgcgca
     9301 gcagtcccca ggtagaaaca atgataacga tcgcaatcaa caggccgata atcgggtcga
     9361 tgatatacca tccggtatgg gcaataacaa ttccggagac aaccacgccg accgatacca
     9421 gtgcatcggc agccatatgt aagtaagcac ctttcacatt caagtcttta tccttatcct
     9481 tcataaaaag ccatgccgta agtgcattta tannnnnnnn nngactccga tacctgccac
     9541 ccaagcgatc gcatcaccct cgaccggacg cggatgcagc agttttccta tactttcagc
     9601 aataataatc ccgacggcca ccaagaggat gaccgcattc agaagggata cgagtacagt
     9661 gcttttctta tatccatagg tatagctgca agtcgggtgc accttagcca gccggaaagc
     9721 cagcatagcc agtaccaggc tggctacatc tcccaggtta tgccctgcgt ccgacaaaag
     9781 tcctaatgaa ttataccaga agccagccgt aaattcggct acgacaaaag ccaggttcag
     9841 ggaaatacct ataatgaaag ccttgttcaa agaggttatt tcgtggtggt gatgatcgtg
     9901 atgatgttgt tccatattca ttcctacttt tatttgagta acaatatggg acaaaactat
     9961 gttttttaga gcaataaaaa tatacctgat tataggtaaa ttaccagatg gttataccgt
    10021 gcttcttaaa tatttctttg gcatttgcca gacgttcggc cgataaaggt tctacctctt
    10081 tcagtttgta gtcgagacct tgtgcctcgt atttataagc gcccatcgtg tgataaggca
    10141 agagttccgc cttctgtaca accgtatagt ggctgatgta ttcggccagt ttatccaagg
    10201 cttcgtcatt atccgtcagt ccgggcacaa tgacatggcg tatccaaacc gggacaccgc
    10261 gtttttccag ttcgtccagg aaacgtaacg tattatccag tttcacggcc gttagacggg
    10321 gatgcaggtc gggatcgatg gtttttatat ccaataagac caggtcggca tattccagaa
    10381 ccgccagggc tttcggtgtg cagatatagc cggatgtatc gagcgccgta tgaataccgg
    10441 cttcccggca aagacggaaa aactccctga gaaattcagc ttgcaataag ggttctcccc
    10501 cggtgacagt cacgccaccc ttggcgataa agttcttata tcgtaaaacc tcagccaata
    10561 attcttcagg cgtcatctga tatttggcaa gccctttgct atcccaggta tccggattgt
    10621 ggcaatacag gcaacggagc ggacacccct gcataaagac aacaaaacga attccgggac
    10681 catcaacggt cccgaaactc tctagtgaat gtatgtttcc tttaatttcc aactttcaat
    10741 tacaaagaat gattgattgt tcttgaaatc acatccagct gctgttcgcg tgtcagtttc
    10801 acaaagttta ctgcataacc cgatacacgg attgtcaact gcggatagtt ttccggatgc
    10861 tccatagcat cgagcaacag ctccttgtcg aatacgttca cattcagatg ctgtccgccg
    10921 tcaggagtaa agtaaccgtc cagcaggccg accatattgg cgatctgaat atcacgttct
    10981 tttcctaacg ttgcaggaga aacagcgaat gtataagaga taccgtcgtg tgcatgctgg
    11041 aacggcagtt tagcaacaga agccagtgca gcaacagcgc ctttggtatc acgtccgttc
    11101 atcgggttcg cacccggagc aaacggcgta ccaccttcgc gaccgtcggg agttgcacct
    11161 gtcttctttc cgtatacgac attagacgta atagtcagga tagactgtgt cggagttgca
    11221 ttacggtatg tctggtgctg acgcagatat tccatgaact tttcagtgat gtcgacagca
    11281 atactatctg tacgatcgtc attgttaccg aaaggaacat aatcgccttc acgttcgaaa
    11341 ccgacagcca ggccacgttc gtcgcggatc acttttactt tcgtatcgcg gatagcagcc
    11401 aatgagtcgg caacgataga aaggccggca atacctgttg cgcggatacg ttctaccgaa
    11461 ccgtcatgca aagccatctc gaatgcttca tacgcatatt tatcgtgcat gtaatggatg
    11521 atcttcagtg cgttcacata aactttagcc agccagcgca tcatctgttc gtatttctcc
    11581 atcacttcgt tgtaatccag gtattcgctg gtgatcggtt caaacctcgg agccacctgt
    11641 acacctgatc tcgcccgccg ttgatggcat acagcaaaca tttagccagg ttggcacgtg
    11701 cgccgaaata ctgcatctgc ttaccgatct tcatcggaga cacgcagcag gcaataccat
    11761 aatcatctcc ataatccgga cgcatcagat cgtcgttctc atactggata gcggaagtat
    11821 cgatagaaac cttcgcacag aaacgtttcc agttttcagg agcgttgttg aaccacagta
    11881 ccgttaagtt gggttccggt gccgggccga ggttatataa tgtatgcaga taacggtaag
    11941 atgtcttcgt caccaatgaa cggccgtcga caccctgtcc gcccaaagac tcggttaccc
    12001 aaacagggtc accggagaac aggtcgttat attccggagt acgaaggaaa cggacgatac
    12061 gcagtttgat aataaactgg tcgatcagct cctgagcttc ttcttccgtc agcttgcctt
    12121 cgcggatatc tttttcaata taaatatcga ggaaagtaga agtacgtccc aacgacatgg
    12181 cagccccatc ctggtccttc accgcagcca gataacccag atagacaaac tgaaccgctt
    12241 cgcgtgcatc ctttgcaggc ttggtcacgt cgaaaccata accggcacac atcttttcga
    12301 aagccttcag cgccttgatc tgttcggata tttcctcacg gctctggatg atctcttcgg
    12361 tcagttcctg aatatcgagt cttttcagat aatgtttctt ttcagcgatc aggatttccg
    12421 taccgtaaag tgctacacgg cggtagtcac cgataatacg tccgcgtccg taagcatccg
    12481 gcaggccggt gatgatagcg gaacggcgcg ctgcaagcat ttcatctgta taagcggaga
    12541 atacgccttc gttatgcgtc tttctgtatt tcgtgaagat ttcttttgtc atcgggtcca
    12601 gtttgtagcc atatgcttcc agactgtttt ccaccatgcg ggtaccacat ttcgggtaaa
    12661 taccgcgttt caggggggca tcggtttgca ggccgacaat tacttcgttt tctttgtcaa
    12721 tataacctgg tccgtaagta tctatacctt gaggatattt tgtttcagcg tcgtaaacac
    12781 ccttctccct ttcaacctta aacatttcgg tcaatttatc ccaaactttc ttcgtcttat
    12841 ctgaggagtc tttcaagaaa gagtcgtccc cttcgtaagg tttgtagttg ttctggataa
    12901 aatcccttac gttaatctct cttttccaaa tttcgccttt gaactgcgcc cagttctcgt
    12961 tttcaaactt cataccttat tttgttttct tcggttttaa tttcggtgca aaggtacgtt
    13021 atttatatgg catgcgaaac aatcaacaaa aacatcatgt attcccaacg gccaaaatcc
    13081 ctacaaatag ttactaaaac ggtagatata gtgcagcgta tcgcctgata taggtatcaa
    13141 acaggaagga ttataaataa tatcaaaaaa ataaaaaagg aaccatcctt cgcaggagag
    13201 tccctttttt atgccggaaa caaccaataa aaaatttccg acacacgttt aatcatctta
    13261 tatgcttaca taattagcaa aaggttttga tatagcgatt atactaatag tgttactttt
    13321 ttctatgttg caaagataga gccgtcaagg ggagtacaca atacctatta tatagtaaaa
    13381 aaagagcttc ctactaccta ttctgtgtta taatcgggaa aattgatcat tggaataaac
    13441 aatatttgca aaaattgctt tctttgataa ataaaaaaga gccattcttc acaggatggc
    13501 tcccttttat atatgaaagg gacaaccaat aaaaaaactc ccttccatgg gtatttacct
    13561 taaataatag gtgtacataa aaatcaacaa atcggatttt ggtcaggacg atttatacta
    13621 atagtaaaac ttaattgata cggcaaaggt aaaaccacgg aaaggcacag gcaataccta
    13681 tatatatgta aaacgagctc a
//
