LOCUS       c00102_gnlPro..        12279 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HGILLCGL_102.
ACCESSION   c00102_gnlPro..
VERSION     c00102_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:47:58
            Original ID  :: gnl|Prokka|HGILLCGL_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12279
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12279
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6148:12141]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6149..12141
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..12279
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12279
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..92)
                     /locus_tag="ctg102_1"
                     /transl_table=11
                     /translation="MNIMSVNGLWRKQTYFLFVHSRKGKHTFIN"
     CDS             complement(761..2350)
                     /locus_tag="ctg102_2"
                     /transl_table=11
                     /translation="MKRFINISFLSLVFAGMALTGCNDDLTTSSYVKVNDEDVLGNVSQ
                     LEKVLTSAYKQLYFNTDKGDRVYAGLPGFQMYVDASGADVISHTNMGGDQVTAYQYSNS
                     KTQADGNASKIWSMCYNVINRANIILTNVDAAAGDETQKKHIKGQALAMRGIQYFHLIQ
                     NYQQTYAIAKSKRGVILRTSSDDESHKGFSTVEEVYTQIVSDLTTAKTLLADYNPDDMW
                     LINSKICSGILARVYLVMQNWDGAYNEAKIVYDQHSQLMTREQYRSGFDDMISGNYAEV
                     VWAMKYTADNNLGGSTQFNFWYNQDASYGEGYADGPIYSFLDYFVDEQFVKLFEEKEDR
                     YQFWKRTNNANTEINTKWAFDKYKHYGEDGGSVIQSATRPEVCLMRGAEMLLIMAEAAA
                     QKGNSGEALNLLNRLQVARNATPTTNAGGEALLEDIYVERRKELICEGQAGFYDLVRLQ
                     KRLVRIGESTTNPAGHYVWGMQYLNGYNALDPQPIGTLESNDYRFFCQIPQMEILNNDA
                     ISESDQNPWSGQ"
     CDS             complement(2369..5647)
                     /locus_tag="ctg102_3"
                     /transl_table=11
                     /translation="MISVLLGAAGAIAANPTGPETMVVQQGNKVTGLVEDQMGPVAGAS
                     VVVKGTTIGTITDIDGKFTLDNVRRGAVIVISFVGLATQEITWNGQSILNVKLSDATQD
                     LDEVVVVAYGTAKKSTFTGSASVVKAEKLEKIMGSGFAEALQGMSAGVNVVNVQGNPGA
                     DARVEIRGIASMSGKADPLYIVDGMPYDGKLNQINPTDIESMTVLKDAAATSLYGSRAA
                     NGVVMITTKRGKSEKPRINFRGGWGTSDNAVKNPKKADPYQQLENTWYALYYDALLYDG
                     MNMQQAGDYASSQALTKQVKATKDSNGNLIYVTPFRHINENYVLHDGNGNPYMNPNLEY
                     VWDEDDWDVYKAIFSRKLRQDYSVDISGQANGGKTAYFFSGGYLDDQGYGNRQYYKRYS
                     FRTNLSTELFDWWKVAGSLSYSRHRQNLSGGASRAANFTTTLSSPWLRNEDNTGWVVSE
                     KTGERMYSYGKYTNNFFGAHILNNSGDYWDNPNDDSFDNNMGHILSAQVNTEFTLPFNL
                     KFRSALNIDDYWYRTMQYTSAVHGSGQTAPYGISILADGGYASRYNFNKRSTTWNNVLS
                     GEWMIGDHTISGLVGHEWYTWDSHYEQGWGEGIMELGKYELSNTTKNFGVSGGRDKYSL
                     LSFFGKVDYNFLNKYYLSASLREDGSSRFSSDHRWGTFWSTGGSWRISKEGFMEDLKWI
                     DNLSLRGSYGTTGNDKLIVRESNGKAGDEVLYGYQGTYESDDLYLKSGLKPSTYPTPDL
                     KWESNQQWNIGLDFSVFNRLSGTVEYYSRTSHDLLYYKELPLSAQVGSASGYNMNIGDL
                     RNSGIEITLNANILTTKDFRWDIDANMSTLKNEVTYLPTGPYTYSGTACTYKMEEGKSL
                     YEFIAPQYDGVNPETGVPGWLIRDGNGGWKRTEKQEEVTTDDFVYCGSAIPKVFGAITN
                     NFQFKGIDLSFMFYYSYGSKISDYTYKERIMNRPGVGVIQELVEDRWRQPGDADVLIPR
                     WSYNQYGATVKYADNFVFDNHYWRLRNLTLGYTLPKSLTRKALVENLRVYVTGNNLLTF
                     GPAKKRYTDPETGIMGNSYNGNAETDNGIQGSRRLYMVGIQITL"
     CDS             complement(6149..6838)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_4"
                     /sec_met_domain="IlvN (E-value: 1.7e-20, bitscore: 62.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 8.5e-45, bitscore: 141.9,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LYFSHGFGITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQGR
                     GLNSSYAIFQDATGKAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQGL
                     LLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWMG
                     PFHDATKPVFQKLYSEVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVVR
                     KLRPENN"
     CDS             complement(6978..7202)
                     /locus_tag="ctg102_5"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDETIAVXXXXXXXXXX
                     XXXXXXXXXXXXXXXXXXXXXXXXXKGRC"
     CDS             complement(7244..7975)
                     /locus_tag="ctg102_6"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     KYNMAICNDGKAISRAAVTWI"
     CDS             complement(8012..8566)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_7"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-18, bitscore: 56.7,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             complement(8579..10279)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(10306..12141)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg102_9"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
ORIGIN
        1 atgttaataa atgtatgctt cccttttcta gaatgaacaa ataaaaaata agtctgtttc
       61 ctccaaaggc catttacact cataatattc atatatcatt catttttata tcattttgat
      121 tttgccgtct gtttggttac aggaagtgaa gtttccatac gacactgatt tgcatcaacc
      181 gtttcactga tatcatgtcc actattatcg gttgaaagag aaactatttt tcgcaatgac
      241 atacgtttac tggtaattct ggatcaggtg aaaatactgg attccacgca tcgccagcgc
      301 ctgacctttg atgtgttttt tctgtggtac aaatattatc aggcaactct ttccgatatt
      361 tattatgaga gataaaccgg atttattttc tactaaccct ttcgacatac gaaaaaagaa
      421 gtaatctgga gccggaagta atcgaaaaga ttgccaaagc attagatata cccgaagaag
      481 caattacgga actaggcgaa gccacttcca ttaatatctt ttccggcacc tggcaagata
      541 atgctaattg ccagaattat aatcctacat ttaacccctt agaaaaagtc gttgaattat
      601 acgaacgttt attgaaagcg gagcaggaga aggtggccat gttacaggaa gtgctaaagg
      661 acaaaaagta aaacagtgaa catcaaatgt tacaaataaa agagagggag gcatgtaata
      721 aacacctccc tctcttttat ttatttacaa cagatgaaac ttactgcccg ctccacggat
      781 tctgatctga ttcggagatc gcatcattat tcaggatttc catttgcggg atttggcaga
      841 agaaacggta atcgttcgac tccagcgtcc ctatcggttg cggatcgagc gcattatatc
      901 cgttcagata ctgcatgccc catacgtaat gtccggcagg attggtagtt gattcaccga
      961 tacgaaccaa tctcttttgc aggcgcacca ggtcataaaa accggcttgt ccttcacaga
     1021 tcaactcttt acggcgttcc acatagatgt cttccagcaa agcttcgcct ccggcattgg
     1081 ttgtcggggt agcattacgc gccacctgca aacggttcag cagattcaga gcctcgccgg
     1141 agttaccctt ttgggcagca gcctccgcca taatcagcag catttcggct ccgcgcatca
     1201 ggcagacttc cggacgggtg gcgctttgaa taacgcttcc gccgtcttca ccataatgct
     1261 tgtatttgtc gaaagcccat tttgtattga tttccgtatt cgcattgttc gtacgtttcc
     1321 agaactggta acggtcttct ttttcttcaa atagtttcac aaactgctca tccacgaagt
     1381 agtcaaggaa cgagtagata ggaccatcgg cataaccctc gccgtagctg gcatcctggt
     1441 tataccagaa attgaactgc gtactaccgc ccaggttatt atcggcggta tatttcatgg
     1501 cccataccac ttccgcataa ttgccggaga tcatatcgtc gaaaccggaa cggtattgtt
     1561 cgcgggtcat caactggctg tgctggtcgt agacgatctt ggcttcattg taagcgccgt
     1621 cccagttctg catcaccaga taaacacggg ccaggattcc cgaacatatt ttggagttga
     1681 tcagccacat atcgtccgga ttataatcgg caagcaatgt tttagccgtc gtcaggtcgg
     1741 acacaatctg ggtatagact tcctctacag tagaaaaacc tttatgggat tcatcatcgg
     1801 aagaggtacg caggatcacc ccacgcttgc ttttagctat cgcatacgtc tgctggtaat
     1861 tctggatcag atggaaatac tggattccac gcatcgccaa cgcctggcct ttgatatgtt
     1921 ttttctgtgt ttcatcaccg gcggcggcat ccacattggt caggatgata ttggcacggt
     1981 tgatcacatt atagcacatc gaccagattt ttgaggcatt tccgtcagcc tgtgtttttg
     2041 agttggaata ctggtatgct gttacctgat cacctcccat attggtatgg ctgatcacgt
     2101 cggcaccact cgcatcgaca tacatctgga atccgggaag accggcatac acacggtctc
     2161 ctttatcagt attaaaatac agctgcttat aggctgaagt caatactttt tccaactggg
     2221 agacattccc cagtacatct tcatcgttta ctttcacgta ggagctggtt gtcaggtcgt
     2281 cgttacatcc ggtcagggcc ataccagcaa aaaccaggga caggaaggat atatttataa
     2341 atcgtttcat aaatatcatt ttttacgttt acaatgtgat ttgaataccg accatataca
     2401 gtcttctcga accctgaata ccgttatcgg tttcagcatt accgttataa ctgttaccca
     2461 ttatacctgt ttcggggtct gtgtagcgtt ttttggcagg accgaaagtc aacaggttat
     2521 taccggttac ataaacacgc aggttttcta ccagggcctt gcgggtaagg ctcttaggca
     2581 gcgtatagcc taatgtcagg tttctcagac gccagtagtg gttgtcgaat acgaagttat
     2641 ctgcatattt taccgtcgcg ccatactggt tgtacgacca acgtgggata agcacatccg
     2701 catcgcccgg ctgacgccat ctgtcctcaa ccaactcctg tatcacaccg acacccggac
     2761 ggttcatgat acgttcttta tatgtatagt ccgatatttt ggaaccataa gaataataga
     2821 acatgaacga caggtcgatc cctttgaact ggaagttatt ggtgatagca ccgaacactt
     2881 tgggaatcgc ggagccacag tacacaaaat cgtctgtcgt tacttcttcc tgcttttccg
     2941 tacgtttcca accgccgtta ccatcgcgga tcaaccagcc gggtactccg gtttccggat
     3001 taacaccgtc gtactgggga gcgataaatt catacagaga cttgccttcc tccatcttgt
     3061 aggtacaggc ggtaccagaa taagtgtaag gacctgtagg caaataagtc acctcatttt
     3121 tcagcgtact catgttggca tcgatatccc atctgaaatc tttcgttgta aggatattcg
     3181 cattcaatgt gatttcaatc ccgctattac gcaggtcacc gatattcata ttatacccgg
     3241 atgcactacc aacctgggca gagagaggca gttccttata atacaacaag tcatgggaag
     3301 tacgggaata atattccact gtaccgctaa gtcggttgaa tacggaaaaa tctaaaccga
     3361 tattccattg ctgattactt tcccacttca agtccggtgt cggataggta gatggtttta
     3421 aaccggattt cagatacagg tcatcacttt cataagtacc ctggtatccg taaaggactt
     3481 catcccctgc cttaccattc gattcacgca cgatcagctt atcattacca gtcgtaccgt
     3541 aactaccacg caacgaaagg ttatcaatcc atttcaggtc ttccataaaa ccttctttcg
     3601 atattcgcca tgaaccgcct gtcgaccaga atgtacccca gcgatgatcg gagctgaaac
     3661 gggaagaacc atcctcacga agtgaagcgg acaagtaata cttattcaag aagttataat
     3721 cgaccttacc aaagaacgaa agcagagagt atttatcacg tccgccggaa acaccgaagt
     3781 tcttggtggt attcgataat tcatatttac ccagttccat gataccttca ccccaacctt
     3841 gttcgtagtg ggagtcccag gtataccact catgtccgac cagacctgaa atcgtatggt
     3901 caccaatcat ccattcacca gacaatacat tattccaggt ggtggaacgt ttattgaaat
     3961 tataacggct ggcataacca ccgtctgcca gtatagaaat accataaggt gcagtctgtc
     4021 cgctgccatg tacggcggaa gtatattgca tggtacgata ccagtaatcg tcaatattca
     4081 aagccgaacg gaatttcagg ttgaaaggaa gagtaaactc tgtatttacc tgagcagaca
     4141 ggatatgccc catattgtta tcgaaactgt catcgttcgg attatcccaa taatcacccg
     4201 agttattcag gatatgggca ccaaagaagt tattggtata tttaccgtaa ctgtacatcc
     4261 gttcccctgt tttttcagaa acgacccaac cggtattatc ttcattacgt aaccagggtg
     4321 aagacaaagt cgtcgtaaag ttagccgcac ggctggcacc accggaaagg ttctggcgat
     4381 gacgcgaata agaaaggcta ccggccactt tccaccaatc gaacaactct gtactcaggt
     4441 tggtacggaa agaataacgt ttataatact gccggttacc atatccctgg tcgtccagat
     4501 aaccgccgga gaagaaatag gctgtttttc caccattggc ctgaccactt atatccacac
     4561 tataatcctg gcgcagttta cgggagaaga tagctttgta gacatcccaa tcatcttcat
     4621 cccagacata ttccagatta ggattcatgt aaggattccc attgccgtca tgcaatacgt
     4681 aattttcatt gatatgtctg aacggagtga cataaatcag attaccattc gaatcttttg
     4741 tagcctttac ctgtttggtc aatgcctgcg acgaagcata atcgcccgcc tgttgcatat
     4801 tcatgccgtc ataaagaagg gcatcataat acaaggcata ccaggtattt tccagctgct
     4861 ggtacggatc ggcttttttc ggattcttga cagcattatc cgaagtaccc caacctccgc
     4921 ggaagttaat acgcggtttt tctgatttac cccgcttggt tgtaatcatt acgacgccgt
     4981 ttgctgcacg cgaaccgtag agcgaagtgg ccgccgcatc cttcagcacc gtcatcgatt
     5041 ctatgtccgt aggattgatc tgattcagtt ttccatcgta aggcatcccg tccacaatat
     5101 ataacggatc ggcctttccg gacatggaag caataccacg gatctccaca cgggcatcag
     5161 ctccggggtt accctgtaca ttcacaacat tcacaccggc actcatcccc tgcaatgctt
     5221 ccgcaaagcc ggagcccatg atcttttcga gtttttcagc ttttacaacg gaggccgatc
     5281 cggtgaaggt tgatttctta gccgttccat aggctacgac aacgacttca tccaggtcct
     5341 gtgtcgcatc acttaatttt acatttaaaa tagattgtcc gttccaagtg atctcctgag
     5401 tggccaggcc gacaaaggaa ataacaataa ccgctccccg ccgaacatta tccagcgtaa
     5461 actttccatc gatatcggtt atcgtaccga tagtggttcc tttcactaca acagaagctc
     5521 cggcgacagg tcccatctgg tcctctacca ggccggttac cttattaccc tgttgtacta
     5581 ccatcgtttc cggacctgta ggattggcag caatcgcacc tgccgcacct aataatacag
     5641 aaatcattag tgatctaatt agttttgagt tggtccacat agctaaattc aagtctttaa
     5701 ttaaataaaa ttaatcacaa tagcgttcat ttcattagag gttacacttt tctaagataa
     5761 aagtgactgg catacatttc aataaaataa agttaactaa aacaaagata tactgatcat
     5821 tacacacaac atccttctat atttccactc tacaaactac agtatctcca tcagcaaata
     5881 taacttatca ttatttaata caagcataat tatgtatatt tattgctcta ataaatatat
     5941 tttaaccacc atttaattga tttttttatc taaaatccac attcaaacaa tgacatacat
     6001 attgggatga aaaatcaata acagttgcaa tcaaaaacat tttttaacca ttaacgcatt
     6061 acataaacca taaaaaaacg gcaacccgaa aagccggatt gccgttttta tatcacaaaa
     6121 tgtttaacta ttaatgtatc accatttatt agttgttttc aggacgaagt ttacgaacaa
     6181 cagcacctgc acgccacatt tcactttcgc gaagagcagc cagttctttt tccagacctt
     6241 cacgatagtc aggcttgctg tttgtgtcga tagaacgctg tgcttcgtta ccgcaggcaa
     6301 cttcgctata caacttctgg aacaccggtt ttgtagcatc gtggaacggg cccatccagt
     6361 ccaaagcacc acgctgtgca gttgttgaac agtttgcata catccagtcc ataccgtttt
     6421 ctgcgaacaa cggcatcaat gactgagtca gttcttctac tgtttcattg aatgcttcag
     6481 aaggttcgtg accgttttca cgcaaagttt cgtactgagc caacagtaat ccctggatag
     6541 ctcccatcaa agtaccacgt tcgccggtca ggtcagaata aacttctttc ttgaatgttg
     6601 tttcaaacaa gtaaccagaa ccaacaccga tacccagtgc aatcacgcga tcccatgctt
     6661 tgcctgttgc atcctggaag attgcgtagc ttgagttcag accacgaccc tgcaagaaca
     6721 tacggcgcag tgaagtacct gaacctttcg gagcaaccag gattacgtct acatcagcag
     6781 gagggatgat gtttgtacgt tctttgtaag tgataccgaa tccgtgagag aaatacaaag
     6841 ccttacccgg agtcaggtat tttttgatgc gcggccaaac ttcaatctga gcagcatctg
     6901 aaagcagata ctggatgata gttgcttttt cgcatgcttc ttcgatatcg aacagtgttt
     6961 cgcccggtac ccaaccgtca gcaacggcct tttnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7021 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7081 nnnnnnnnnn nnnnnnttac agcgattgtt tcgtctttca atacttctct tgccttttcc
     7141 aacggaaatt cttcgcgggt tactacgttt tcgtcaacgc cgccaaaatt cattactgcc
     7201 attttctttt tactattaaa atgtatataa aataatttgt ttttcagatc caggtaacgg
     7261 cagcgcggct gatggctttg ccgtcgttac agattgccat attatattta tcgagggata
     7321 cttcctggtt atggagagtc agctccatcc catactttcc ttcggactga taagctattt
     7381 cgaaacggct tatctctttt tctcggaaca gactgatatc gaacaagtcg agcaggtgtt
     7441 ccatgtattt gatactgttc aggtggccgt ttacgtccag gtcactatac ttcacacggt
     7501 aaggttcgcc ggaagtgttg ttttccaccg gagcaatttt acccggtttt tcaatcggac
     7561 agggacggtc ggtgatataa gcactcaggc cctccacatc gagcaaggtc gggcggcggg
     7621 tttccatatc gatagccgcc cagatagagc gggcaaagcc aaaggtcttg ccttcgccgt
     7681 tcaccagttc aaagcaacgg ctggtaaaca acttaccgac ctcatccacc caggtatata
     7741 aagttacgga ttcagacatg gcaggataag aagtcatctc gatagccaga cgggaaagaa
     7801 cccaggcggt atgcctttcg gtcatatcgt tatatccgaa tccacggtcg gcggcatggc
     7861 aagaagcagc atgcaacaaa taagttccga tcatagggat tgtaatacgt ccccggaagt
     7921 ccgtcagata agactctgtt acgaaatgaa attctcctac tttgttcttc tccataattt
     7981 actttattta caaaatgttt ccttattatt ctcagacatg tttttcctgc aacttctttt
     8041 ccattgcaga taacatgtcg ctcagacgtt ctaccttact cttcgttata gcaacgcgtc
     8101 cggaacggat aaattgcagg acaccgatcg tctcactcaa ttctttaaac aaagcctgtg
     8161 tctcatcata atgaccactc ttttccaaca ccacacaatc ctcattcatt tcaaggatac
     8221 gggcattgta cttacggatc agatcctcaa ccgtccccat cttgataaag agttcggtac
     8281 tcagtttata aagagcgatt tcctggtaaa ccaggtcttc atccgtatta taataggctt
     8341 tcaggatatc cacacgcttg tcgatctgtt ttacgacctt gtcgatcgta tcctcgtcgg
     8401 caaaggtagt aattgtaaac ttatgtattc cctttatagc agagggagaa acagaaagcg
     8461 tctcaatgtt cagttgccgg cgcgtaaaga taacagttat ctgattcaga agaccaacag
     8521 tgttttccga aaagataata acggtatata attgttttgt attcatagtt tctcctcctt
     8581 acttatcacc caaaatcatg tttgtcacgc ttcctccggc cggaaccatc ggatatacca
     8641 taccacaagt ttccacattg gcaaccaaca tataggcacc atcgtgattc aacatttcag
     8701 caatcgcctc atccaagtct tcccgtttat ctaccgcacg ggaagcaata ccaaaagcct
     8761 tggctatcgc tacaaaatcc ggattcttca tgatggtatt cgaataccgt tcgttgaaga
     8821 acagctcctg ccactggcgt accattccca ggaaattgtt gttaagaacg atgatcttta
     8881 cattcagatt ttcctgcatg atagttccca actcctggat agtcatctgg ataccaccgt
     8941 cgccggtaaa gaaacagacc gtacggtcag gcgctcccag cttcgctcca atggcggcgg
     9001 gaaggccaaa gcccatcgtt cccaaacctc ctgaagtaac tacgctgcgt gtttgtttat
     9061 atttgaaata gcgaacaccc atcatctggt tctgacctac atccgtaacc agaatcgcat
     9121 cattatcggt tgcttcggaa accttacgga ctacttcgcc cattttcagt tggccttcgg
     9181 taggatagag ttctttttct attaccttat tatattcctc tttttcatcc ggttcgaatt
     9241 cagcattcca ttccggacgc ttccgttctt ccagtaaagc cgtaatcatc ggaatcgtat
     9301 gcttggcatt tcccagcact ttcacgtcga ccggcacatt ctttccgatc tccgaattgt
     9361 cgatatccag gtggataatc tttgcctgct tggcataagt cttcaggtcg ccggttacgc
     9421 gatcatcgaa acgcataccg atagcaatca gcacgtcaca ttcgtttgtc ttgcggttcg
     9481 gtccgacatt tccatgcatc cccaacatac ctttatttaa tgggaagtcc gaaggtaatg
     9541 cagacaagcc caatacggta gaaccggctg gtatatcgtt tttcaacaag aattctttca
     9601 gttcttcttc agctcctccc aggataaccc cctgccctac cagacagaat ggctttttgg
     9661 cattatttat caatgaagca gccgcctcga tacgttcctc cctgatatcc ggttcaggtt
     9721 ggtaactacg aacataatcc actttctgat actcataatc taccaaaccc acctgtgcat
     9781 ctttcgccaa atccagtacc acaggtcccg ggcgaccggt cgatgcgata tagaaagcac
     9841 gggaaacggc ccaagcaatt tcttccgggc ggcgtatctg gtaagcccat ttggtaatcg
     9901 gttgtgtgat accgatcaca tcaacttcct ggaaagcatc tgttccaagc agcggagacg
     9961 gaacctggcc ggcaatcacc accatcggtg tactgtccat cagcgcatcg gcaataccag
    10021 tgatggtatt ggttgccccg ggacccgaag taaccaccgt tactcccact tttccggaaa
    10081 cacgggcata tccctgtgca gcatgtgttg caccttgttc gtggcgcacc agaatatgtt
    10141 ttaactgatc tctgtaatcg tataaactat cgtaaattgg tatcgcctgc ccacccggat
    10201 aaccgaagat agtatctact ccttcagcga tcagcgcttt cagcaaagct tccgaaccgg
    10261 ttatcttttg tttgtccatc tctaaaatat agtatttggt gtttattaat cttctactat
    10321 tcgtacaccg cccttatcgg ccgaagcaac catctttgca tatgctttca gtgctttcga
    10381 taccgtacgt tggcggaaag gaggtgtaaa ggcttttgtt ccgcgggctt cttccgcttc
    10441 acggcgtttg gccagttctt cgtctgtcac ctttacatgt atggttcttt cgggaatatt
    10501 aatttcgata atatcgccgt ctttcactaa gccaatcgct ccgcctgcag ccgcttcggg
    10561 agaaatatgt ccgattgaca aacccgatgt tccaccgctg aagcgtccgt ctgtgattaa
    10621 cgcacattct ttacccagat gtttactctt tatataagag gtaggataca acatttcctg
    10681 catacccgga ccacccttag gaccttcata ggtgataacg acgacatcgc cggagacgac
    10741 ttgatctttc aggatacctt cgcaagcggc atcctgcgaa tcgaatactt tggcagggcc
    10801 ggcaaaacgg aagatacttt catctacccc ggctgtttta accacacaac cgtcctgtgc
    10861 aatatttcca tacagaacag ccagaccgcc gtctttcaca taagcatgtt ccacatcgcg
    10921 gatacatccg gttgcacggt cggtatccag ttctttataa taactttcct gcgatccgag
    10981 caccagattg aaacggtggg ccggagcact tttataaata ttgattgctt cttccgttac
    11041 atttacagag gtaatgcagt attggtcgat agcctcattc aaagtcagac catccgcacg
    11101 tttcacggaa ccgtccacca gaccggcttt taccagctca ttcataatac cgataatacc
    11161 tccggcacgg ttcacatctt ccacatgata agaacaactc ggagccactt tacagataac
    11221 cggtgttttg cgtgaaagca tatcgatgtc tttcattgta aaatcgactt ccgcttcatg
    11281 agccacggcc aacaggtgaa ggactgtatt cgtcgatccc cccatggcaa tatccagcga
    11341 catagcattc agaaaggcct gacgggtggc aatactgcga ggcaatacgg aatcatcgcc
    11401 gtcacgataa tatttaaagg cattatcaac aatcatcttc gcggcttttt tgaacaggcg
    11461 ggtacggttg gcatgtgttg caacaactgt tccgttgccg ggaagagcca atccaatcgc
    11521 ttcgttcaga cagttcatag agttagccgt gaacatacca gaacagcaac cgcaggtcgg
    11581 gcaagcggaa cgttccacct tttctacttg ttcatcgctg atagaatcgt cagccgcttc
    11641 aatcatggcg tcgatcaaat cgagtgcacg tccgtccaga ttaccggctt ccatcggacc
    11701 gccggataca aagattgtcg gaatattcag acgcatactg gccatcagca tacccggagt
    11761 aatcttgtcg cagttactga tacaaaccat tgcatcagcc ttatgcgcat tcaccatata
    11821 ttccacactg tcagcaatga tgtcgcggga aggcagagaa taaagcattc cgtcgtgtcc
    11881 catagcaata ccgtcatcaa tagcgatcgt attaaattct gcggcaaagc aaccgagctt
    11941 ttcgatttcc gcttttacct gctgtccgat ctcgtgtaga tgcacatggc ccggtacaaa
    12001 ctgggtaaat gaattcacaa tggcaatgat cggtttaccg aactgttctt ctttcatgcc
    12061 gttggcacgc cataatgcac gggctccggc catacgtctg ccttctgtgc tataggagct
    12121 tcttaacgga ttcttcatca tatctgtttt tatcttttag tcaataaaaa agcccttctc
    12181 tatatggaga aaggcttaag aaatatcttt tacgacttca caacttctta cacacctttc
    12241 tccttaccta ctaatgacta gaaggaccac cacgagaat
//
