LOCUS       c00046_gnlPro..         6654 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLACILEH_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 07:21:20
            Original ID  :: gnl|Prokka|NLACILEH_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6654
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6654
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[392:3882]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      393..3882
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..6654
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6654
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(393..1160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-24, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.4e-12, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-07, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1201..3159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.7e-55, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3181..3882)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4083..4355
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4388..5173
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5207..5440)
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5872..6579)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
ORIGIN
        1 attataattc ttacgctcaa cacctccctg ttatggacat caatgttgtc tgtttgttag
       61 aaaatatttt cctctcatgc agaacccttg acaggatgcc atcccttccg ggcatcagtc
      121 caattcctgt aatcaatgtt tctttctctc gaagaaagat gggggccgtc gctgtcggac
      181 gggggcttgc ttaggtttcg tccggcattt ccaagtacgg tctcctggat tactggaacc
      241 cttccggtgt aacaattttt tacgctgcgc gacgatgagg aagcaactgt ctggtatttt
      301 attcctggtt caaggaaacc tggtaatgaa aaaactcccg acagccgatg ccgccgggag
      361 tttttacaga gcgtcttaag aaggaatctt ctttagaaac agaggccttc cttggcgttg
      421 gcccgcatga agtcgcggtt gaggcgggcg atgttgtcca cgctgatgcc tttcgggcag
      481 gcggcttcac attcatactg gttcgtgcag ttgccaaagc cttccgcttc catctgcttc
      541 atcatggcca ggacgcgctt ggaacgttcc ggctggccct gcggcagcag attgagatgg
      601 gcgatcttgg cggaggtgaa cagcatggcg gaggcgtttt tacaggaggc cacgcaggcg
      661 ccgcagccga tgcaggcggc cgcgtcaaag gcggcgtccg ctttcacttt ttccacggcg
      721 atgttgttgg cgttcggcgc ggaaccggta cgcacgtcaa tatagcctcc agcggcgatg
      781 atgcggtcca gggcggagcg gtccaccatc aggtcccgca ggattgggaa agccttcgcg
      841 cggaagggtt caatccagac ggtatcgcca tccttgaact tgcgcatgtg aagctggcaa
      901 gtggtcacct ggcgttccgg cccgtgggga atgccgttga tggtcaggga gcacatgccg
      961 cagatgcctt cccggcagtc gtggtcaaaa tggatgggtt ccttgccttc cttgaccagg
     1021 ccttcattga cgatgtccag catttccagg aaggaggcgt ccaccggaat gtccttggcg
     1081 gcataggtct caatgcggcc cttggcttcc cggttttcct ggcgccagac cttgagagtg
     1141 agattgagtg ttttagccat gttataatct ttcttttgag tgttaatgta ttggctatct
     1201 ttacttgtag ctgcggatgg caaggtgcac gttctcgaag gtcagcggtt ccttgtggag
     1261 aacaggcagg ctgtccacgc cagtgtattc ccaggcggct acataggcgt attcatcgtc
     1321 gttgcgctta gcttcgccgt ccggcagctg gtattccacg cggaagtggg cgccgcagga
     1381 ttcctggcgg ttcagggcgt catagcagag cagctgggcg aattccagga agtcggccac
     1441 gcggcaggct ttttccagtt ccgcgttgat gccgtccgcc gtgccggtta cgcgcacgtt
     1501 ttcccagaat tccttgcgga gctggggaat gcgttcaatg gcgtgggtca ggctttcttc
     1561 cgtgcgggcc atgccgcagt cttcccacat aatgaggccc agttcccggt ggaaggagtc
     1621 caccgtcttg gtgcccttca cattcaggag cttgttgatg cgttccttca cttcgtcttc
     1681 cgcagccttg aattccgggg cggcggtggt gacggcgccg ggtttggtgg tcgtcaggta
     1741 agcgggcagc gtggcgggaa tgacgaagta gccgtcagac aggccctgca tcagggcgga
     1801 ggctcccagg cggttggcgc cgtggtcgga gaagttggct tcaccgagga cgtgcagccc
     1861 cttcacattg gacatgaggt tgtagtccac ccacaggcca cccatggtgt agtgggaggc
     1921 ggggtagatc atcatgggcg tttcatgggg gtcgtcgtcc gtgatttctt cgtacatgtc
     1981 aaacagattg ccgtattggc cgtcaatcca ttcgcggccc atgcgcttga tttcatccgc
     2041 aaaatctagg aagacgccct tgccggtgac ggccacgccg cggccgtcgt cgcaggcttc
     2101 cttggcggcg cgggaggaaa tgtcgcgcgg agccaggttg ccgaaggagg gatacttgcg
     2161 ttccaggtag tagtcccgtt cttcttcggg aacatcggaa ggcttgattt cctttttacg
     2221 gattttttct gcggtttcac gggacttggg cacccagatg cggccactgt tgcggaggga
     2281 ttccgacatc agcgtcagtt tggactgata gtcgcccttg accggaatgc aggtggggtg
     2341 gatttgcgtg aagcaggggt tggcgaagaa ggcaccgcgc ttgtaggcct tgtaggcggc
     2401 agtgacgttg cagcccatcg cgttggtgga caggaagaac acgttgccgt agccgcccgt
     2461 gcagagcagg acggtatccc ctgcgtagga tttgatttcg ccggtaacca gattgcgggt
     2521 gacgatgccc ttggcttcgc cgtccaccag caccagatcc atcatttcat ggcgggagaa
     2581 catttcaatg tgtcccttgg ccacttcctt ttccagggcc tggtaggcac ccagcagtag
     2641 ctgctggccc gtctgtccgc gtgcgtagaa ggttcgcttg agctgggcgc cgccgaagga
     2701 gcggttgtcc agcaggccgc cgtattcacg gccgaaggga acgccctggg ccacacactg
     2761 gtcaatgatg ttggaggaga cttccgccag acggtagaca ttggcttcac gggcgcggaa
     2821 gtcgccgcct ttaacggtgt cgtaaaacag gcggtaaacg gagtcgccgt cgttctggta
     2881 gttcttggct gcgttaatgc cgccctgggc cgcaatggag tgggcgcggc gggggctgtc
     2941 ctggtagcag aagcatttga cgttgtagcc aagttcggca agcgtggcgg cagcggaggc
     3001 gccagccagg ccggaaccta ccacaagcac cgtgtacttg cgcttgttgt tcggattgat
     3061 cagtttggac tcaagtttgt acttggacca tttgtcctga atagggccgg agggaatttt
     3121 ggcatccggc atccagtcgc ttacgggaaa attaatcatg actttgagag gagttgatgg
     3181 ttatttgatg atacccagaa gaaccgagac cggcacggag atgaagccca ggcagataat
     3241 cgcgccgtag gcgatggcga taaagttgta gaagggccgg attttgcggg aatcgacgcc
     3301 cacagtctgg aagatggact gtaccccgtg gcgcagatgg ctgaacagca tcagaacggc
     3361 caggatgtag aaggcggagc accatacgtt ggagaatccg gtcacgatca tcttgtacac
     3421 gtcaaaggtt tccaccgtac cgtcggaaat gaaggtggtg aactgggcgg ggtcgtatcc
     3481 cacgcgcagg gtgtactggt acaggtggta gatcaggaac accaggacgg tcaggccggt
     3541 atagatcatg tagcgggagg agagcgtcgc cttgatggtg ttcttgaaca cgtagggttc
     3601 gcgggccgca tggttttcca gcttcagctg gatggtcagc cagacgtgga tgatgaagat
     3661 caccgcaagc cccgcgcgga ttccccagag ggctgcttcc ggcatggagt gcaggccgtg
     3721 ggcgtaggtg ttgatccatt cagggcctcc gaagatgaga aggttgcctg ccaggtgtcc
     3781 cgcaaggaac aagaccaaac ataaccccgt cagagccaca atgattttgc ggccgatgga
     3841 ggatgtcacg aatgtacata tggtttttac tagtgcattc ataggcgctc taatgaaata
     3901 aatgcgtctt cacaggatgc ctggttcaag cccggatggc aagcctcttc ttgaatttcc
     3961 ggcgcttttc ggatttttga aaagccgggg aaagatgttg ctgtttatca gtttggaatg
     4021 gttatcattt tgttgcctgt tccggcttga cgaggctttc cgcataggcg tatcgtctgt
     4081 gcatgaaaag aagtaaaaag gaagtgctgg acgcggattt cgcagcggcg cgcgccggcg
     4141 ttctggatgt ggccgcattt ctggaccggg tggaccgcgg ggaaggggag gcggatttcc
     4201 gctaccatgc cctgatggat gttcttcccc tcttatccgc atccggcccc ggacgcgtcc
     4261 gggccatcct ggaagccctt tcctacaggg atgacaccgt gccggaaacc gccgcagcca
     4321 aagcggcctg cggagccccg aacctcagca aataagaatg atggctttca tagaacctca
     4381 tatacatatg gtgtgccgca ccacggacga ataccgggcc atggcgcagg ccggctgcct
     4441 ggcggtaggg gaaccggcgt tctgggccgg ttacgaccgt tcgtccgcgg acggtttccg
     4501 ggattatttc gtacagctta cggaatgcga acccgccagg gcggccaagt tcggcatgga
     4561 ccattacaca tggctgtgca tcaatcccaa ggaggcgcag gacgtggctt tcgcgcggga
     4621 tgtgatgaag ctgattccgg agttcatcga ccggcccaat gtcctcggca tcggggaaat
     4681 aggactgaac cggaatactt cccatgaaat gactattttt gaagagcatc tggatctggc
     4741 ggtgcgcctc aaccagcttg tgctgattca cactccccat ctggaagaca agcttaaggg
     4801 gaccgtaatg attctttccg ccctgaaaaa ccgtccggat ctggaccctt gccgcgtgct
     4861 ggtggatcac tgtgaggaac ataccttccc gctggtgaag gaggccggtt actgggccgg
     4921 gctgaccctt tatcccacca gcaagctgaa tcccaagcgg gcggcggata ttctggaatt
     4981 gtacggaatg gaccgtgtct gggccaattc cgcggcggac tggggggatt ccgatcccct
     5041 ggcgctgacg gccctggcct gcgagctgcg caggcgcggt ttttcccggc aggaaacgga
     5101 acgtcttctc ctggaaaatc cggagacatt catgggacag tccccgaagt tccggaaagt
     5161 gtcgtcccgc taattccgcc cgaggcgcgg cggagggtac ggccctctag tccccgtccg
     5221 ggaaaaagac ggtgaggacg gcgcccagga tgaccgccgc gtcatccaga aggcccagcc
     5281 tgccgattcc gtcaaacagg aattcgtcgg gagtcaggat gtaggcgccg gcggcggcca
     5341 gaaggcatat attccgtttg ttgaaaaaac gcggttctcc ttttctgctt ttgaaatacc
     5401 ggaacaggcg cagtagcagc tgctgttttt gaaggttcat ggacgggaac gggggataaa
     5461 ggttcaagct cagccatttt cccactcctt ttccctgttt cggggaagga gtctgttgcc
     5521 gacggacgga aaccgcagcg atccggaccg tgcggggaaa tggattgctg aaaggatggg
     5581 ctgttccgga tgctgaggga agccgggctt tgcatgctcc ggttccggct gtcccggcat
     5641 gggaaaaagg ggcgtgtacg gaagtggggc ggggccggaa gctcttgaaa tgaccctccc
     5701 gggggagcct gaatgccatt tccccgtcaa gtgctggccg tgagggtacc gcagcaaatg
     5761 gaagcttctt cccccctgtt ttttccggca gatgtttgaa cggataagga aaaggccggc
     5821 tcacgatttt gtgagccggc ctttgaatat agggaggcgg acggtacagg cttatgccct
     5881 gcggcggcgc atcatcagcg cggccagtcc cagcaggccc agggaagccg tggcgggttc
     5941 cgggatgctg gcgatttcac tcatcagttg accaacttgt tcctgggaaa ggagggagtc
     6001 gtgaatgtag agctgttcga tggattcagc cagtcctgcg tccatgagaa tctgatcaat
     6061 ttgctggttg ccgaatttca ggccgctgtt ggaatagtac gtagtgctgt ctccaaaata
     6121 gatgcgggtg ccaagatctc cggtgactac ggaaatggtc agggaacctt ccgtgcccag
     6181 cggggtgtca acgacaggcc cgctgtagga ggtgttgttc cataatccct ggagtttccg
     6241 gtccgtgttc aggcccacgc cccagcttac actgctgttt ttggcgttaa acagagcggt
     6301 ataggcgtcc ggagtgttga ttttggacag gtcaagaacc atcgtcacag acataacgtc
     6361 gcggttgttg gcaccgtatc cgttgaaggt tatcccggat aacgtcagat tgctgtcgtc
     6421 agacgtgatg gaaacggaat ctttcagggt gccgaaatcc gccgtttggg aggcaaagtc
     6481 cgaatatccc acgatggagc tatccagcag agaggtagcc gcggtagcgc ttaggctcat
     6541 gccgaccgaa agaatcaggg tggataataa tttattcatg gtcagtatct taataaaatg
     6601 atgcaagatt caatgtatgt acttgtgctt gaataacgaa tttggaatcc gtag
//
