LOCUS       c00056_gnlPro..        12511 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LGOFKNNH_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 05:55:23
            Original ID  :: gnl|Prokka|LGOFKNNH_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12511
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12511
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6397:11106]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6398..11106
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..12511
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             144..1151
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="MRKLLVLCSFWLCVATLGAQNAERKLYSVAFYNLENLFDTVHDAG
                     KNDHEFLPDGSYQWTVKKYESKLQNLSKVLGSLSRDLVPEGPAFIGVAEAENSRVLEDL
                     VKQPAISNYEFVHYEGPDRRGIDCALLYDPKQFSVTHSKLVLSTPFEGDTVHLTRGFLI
                     VDGQLAGERVCVIVNHWPSRGAKSPVRVHAARQVKALKDSLMRSDKKLKLIVMGDMNDD
                     PMDESMEVLGARKYPKQVKKGEFYNPWWETLEDKGVGTLLYRGKWNLFDQIVISKPLLK
                     AKKGLRYDHNEVFIRDYLIQQDGKYKGSPLRTHGGRTWLNGYSDHLPTIIYLKN"
     CDS             1434..2444
                     /locus_tag="ctg56_2"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCKHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVDYAHQFDVTVEGELGVLAGVEDEVSAEHHT
                     YTNPEEVIDFATRTGCDSLAISIGTSHGAYKFKPEQCHVDPATGRLVPPPLEFAVLDAV
                     MEKLPGFPIVLHGSSSVPQEEVDTINKYGGKLEAAIGIPEEQLRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSENKLAQLD"
     CDS             complement(2915..4765)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_3"
                     /sec_met_domain="Alpha-amylase (E-value: 2.3e-64, bitscore:
                     207.4, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVFLILGTLLLSLSTYAAMNVNKIDPPFWYTGMQNPELQLMVY
                     GEGIGNAAVSVNYPGVSLSSTVKLESNNYLLVYLKLDKDVKPGKFNLTFTEGKKKLVKE
                     YELKARNKKGCEHKGFDASDALYLLMPDRFANGNPDNDQIAGMADYKVDRNDPNARHGG
                     DLAGIEQHLDYFSDLGVTALWFTPVLENNMTGGSYHGYATTDYYKVDPRFGTNEEYKQL
                     IEKAHARGIKIVMDMIFNHCGVEHVWIKDMPSKDWFNNPDHENNFVQTSFKLTPHVDPY
                     TSQYDADQMNNGWFVPSMPDLNQKNPHVYRYLVQNSFWWIEFANIDGIRMDTYPYADYD
                     AMSNWMKELNEEYPNYNTVGETWVTEPAYTAWWQKDSKLSAPKNSNLKTVMDFSFFDKI
                     NTAKNEQTETWFKGLDRIYNNFVYDFLYPNPASVLAFIENHDTDRFLGEGDNLPMLKQA
                     STLLLTTRRIPQLYYGTEVMMNGVKSKSDGYVRKDFPGGWTGDATNALTPAGRTKIQNE
                     CYDFYKTILNWRKGNDVIAKGSMVQFMVQNGVYAYARQYEGKTIFVMLNGTDAETTVPL
                     KFYKEILKNSKQGKDILSGKAITFGEELKMGPRESLVIEL"
     CDS             complement(4876..6228)
                     /locus_tag="ctg56_4"
                     /transl_table=11
                     /translation="MRKLFISLCFSACCSLLAAQTTNPIQEAMANYDYETALMLIDQET
                     PTVPLLYQKGKALKGLGNNLEALSVFQEVVAQDSLNPRAYIEAAECCKSLAKYSEALDY
                     YQNALHINPDNKYARIQYISLLMNMKRYRESLKESNLLAERDSSAYVLHLRAESMGQVY
                     DNTEIMHVIDAYLDIQKRYPNDYLSAAKLGNIYVAGHQYEDAINITEIYRSIDSTNVLV
                     NRINAQAYCLNKDYPKAIERYEQLLQEKDSSFQTCFYAGISYYALEDFYPAHDLLERAL
                     KDDNTNINVLYYLGRACSKTSWKEDGVTYLETAVSLAMPSDSVMSRLYVGLADCYKMAF
                     QYTDQANTLLTQYEKYDRQKHKLLYDAAFIYYYYLKDASKAERYLTAYLKTRPKNSKDK
                     VQEVDADGVPIIGEDNRYNAAENWLKDIREKRKKEDFFKGKVDTASVTPIK"
     CDS             complement(6398..7558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_5"
                     /sec_met_domain="OAD_beta (E-value: 3.9e-153, bitscore:
                     498.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEFITFLGNNLADFWTYTGFANATVGHVVMLLVGLFFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMEAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYMIALAIGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRWLTSKNERLIRMKPPRVVSHTEKVMFP
                     IIGLLLTTFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFGLGALSFVIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(7560..7994)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.3; E-value:
                     2.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_6"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.4e-22, bitscore:
                     67.3, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNVYKVAIGDIEDNIAHVEVNGTPYKVEMEKAPKVV
                     VKPVARPAATSAPAAPATPVVKPAAASTGKSGVKSPLPGVILDIKVNVGDTVKKGQVII
                     ILEAMKMENNINADKDGKITAINVNKGDSVLEGTDLVIIE"
     CDS             complement(8018..8950)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_7"
                     /sec_met_domain="OAD_gamma (E-value: 8.4e-18, bitscore:
                     54.3, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLMLVLGFCSSCKEQKSNNKLLLNEVLVNNESNYQ
                     DDYGVHSAWIEIFNRSYGSADLAGCYLKFSSQPGDTASYFIPKGDVLTLIKPRQHALFW
                     ADGEPRRGTFHTNFKLDATNANWIGLYDSGKKLLDQVIVPAGTLKANQSYARVSDAADQ
                     WEVKGGSEDKYVTPSTNNKTIDSNAKMEKFEEHDSVGIGMAISAMSVVFCGLILLYISF
                     KIIGKISVNLSKRNAMKAKGITDKQEAKEKQLGQAPGEVFAAISMAMHEFQSDVHDVED
                     TILTITRVKRSYSPWSSKIYTLRETPHKK"
     CDS             complement(8982..10535)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_8"
                     /sec_met_domain="CT_Btheta (E-value: 1e-291, bitscore:
                     956.9, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIDRRAAARLGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYIFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGLALIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDNPN
                     KPYDMYEVIGAIIDNGEFLEIQKDYSKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKEQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRIIRALQQLQTKKLTNPAKKHGNIPL
                     "
     CDS             complement(10594..11106)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_9"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3.2e-26, bitscore:
                     81.2, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFFIKEEFSFFVLLYTFIKKDTILTLIYIVMKISHIEHLGIAV
                     KSIEEALPYYENVLGLKCYNIETVEDQKVRTAFLKVGDVKIELLEPTSPESTIAKFIEK
                     NNGNGGMHHLAFAVEDGVAGALAEVEEKGIRLIDKAPRKGAEGLNIAFLHPKSTLGVLT
                     ELCEKPE"
     CDS             11300..12511
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MKKNILLAVCFLMPLATMAQNDTLGHERNITLSEAIVLARTQSVD
                     AAVALNELKTAYWEYRTFRADLLPEVNFTGTLPNYNKSYSTYQNSDGSYSFVRNNTLGL
                     SGQLSVDQNIWFTGGKLSLTSSLDYLKQLGSGGEKQFMSVPVSLELTQPVFGVNTLKWN
                     RRIEPVRYAEAKAEFISATEEVTMKTITYFFELLLAKESLATAMQNKTNADRLYEVAIA
                     KRKMGQISENDLLQLKLNSLQGKADVTEAESNLNAKMFQLRSFLGVSEQESLNPVLPAT
                     VPDIKMEYDRVLNKALERNSFAQNIRRRQLEADYEVATARGNLRSIDLFASVGYTGQNH
                     EFSSAYRDLLDNQIVQVGVKIPILDWGKRRGKVRVAKSNREVVLSRIRQEQMDFNQDIF
                     LLVAN"
ORIGIN
        1 aataaatagt gtaatggtct tcttttcaga gcgcaaagat agtgcaagtt ggagactcta
       61 caaaataaat tcagatttat ttttatttag taggtttatc gcattttatt tctgattttt
      121 gcaggactta atcttgtgaa tttatgagga aactacttgt cttatgctct ttctggctgt
      181 gcgtggcaac gctgggggca caaaatgcgg aacggaaact gtatagtgtt gcgttctata
      241 atcttgaaaa cctgttcgat acggttcatg atgccggtaa gaacgaccat gagttcctgc
      301 ccgacggcag ttaccaatgg acggtaaaga agtatgagtc caagctgcag aacctttcca
      361 aagtgttggg ttccctttcg cgtgatttag tgccggaagg tccggcattc atcggtgtgg
      421 cagaggcgga gaacagccgg gtgctggaag acctcgtgaa gcagccggcc atttccaatt
      481 atgagttcgt gcattatgaa ggaccggaca gacggggcat cgactgtgcc ttgttgtacg
      541 acccgaagca gttcagcgtt acccactcaa agttggtgct ttccactcct tttgaggggg
      601 atacggtgca cttgacgcgc ggcttcctga ttgtggacgg acaactggcg ggagagcgtg
      661 tctgcgtgat agtgaaccac tggccctccc gtggggcgaa gtcaccggtg cgtgtgcatg
      721 cagccaggca agtaaaggcc ttgaaggact ctctgatgcg tagcgacaag aagctgaagc
      781 tcatcgtgat gggggatatg aatgacgacc cgatggatga aagcatggag gtgctgggtg
      841 cacgcaaata tccgaagcag gtgaagaaag gcgaattcta caatccctgg tgggagacac
      901 tggaagacaa gggagtgggg acattgctct atcggggcaa gtggaacttg tttgaccaga
      961 ttgtcatttc gaaaccgttg ctgaaggcta agaaagggtt gcgctatgat cacaatgaag
     1021 ttttcatccg cgattatctg attcagcagg atggcaaata caaaggttcc cccttgcgta
     1081 cgcatggagg caggacttgg ctgaacggtt acagtgacca tttgccgacc atcatctatc
     1141 tgaaaaatta gtattacata ataatgtgta aacagatgcc ggagagcaaa catgttctcc
     1201 ggcttttttg ttgatagaag tatagatggc aaaagtatgg ctggcagaga taaatgcaaa
     1261 gagtttgtaa tatagagatt acaataatct gttaaatgaa gccaatagct ttaaaataga
     1321 atggatttgg taggatgagc cggatatttt attcctctca agttctttac tttaaaggat
     1381 aatgattact tttgcgtaga attttaattc actaacaata aaatttaaac aaaatggtta
     1441 attacaaaga tttaggactg gtaaacacaa gagagatgtt tgctaaggct atcaaaggtg
     1501 gatatgctat tccggcattc aacttcaaca atatggaaca gatgcaggct atcatcaagg
     1561 ctgcagttga aacaaagtct ccggttattc ttcaggtatc taagggtgcc cgtcagtatg
     1621 ccaacgctac gctgttgcgt tacatggctc agggtgctgt tgagtacgct aaggaattgg
     1681 gttgcaaaca tcctgaaatt gttcttcacc tcgaccatgg agatacattc gaaacttgca
     1741 agagctgtat cgactccggt ttctcttcag taatgattga cggttcacac cttccgtacg
     1801 aagaaaacgt tgcactgact aagaaggtag ttgattatgc tcatcagttc gacgtaactg
     1861 tagaaggcga actcggtgta ttggccggtg tagaagatga agtttctgca gaacaccata
     1921 catatactaa tcctgaagaa gttattgact tcgctacccg tacaggttgc gattcactgg
     1981 ctatctcaat cggtacttct catggtgcat acaagttcaa acccgaacaa tgccacgttg
     2041 accctgctac cggtcgtctg gttcctcctc ctttggaatt tgccgttctg gatgctgtaa
     2101 tggagaaact tccgggattc cccatcgttc ttcacggttc ttcttcagtt cctcaggaag
     2161 aagttgatac tatcaacaag tatggtggta agctggaagc tgctatcggt atccccgaag
     2221 agcagttgcg taaggctgcc aagtctgctg tttgcaaaat caacatcgac tctgactcac
     2281 gtctggctat gacagctgct atccgcaaga catttgctga aaaaccggca gaattcgacc
     2341 cgcgtaagta tctgggtccg gctcgtgaca atatggaaaa actgtacaag cataaaatca
     2401 tcaacgtgct tggttcagag aacaaattgg ctcaactgga ctaatcgaaa gataatccga
     2461 atatagcgtc agcccttgca atattgatgt tgcaagggct gacttgttgt atataggccg
     2521 gtgttgtggg atggttaagt tcgccgctta tttcagaagc ggatgtttca acgtgtacaa
     2581 cagtctgttt cctttaacaa aacagtctgt ttcccttaac tgaacagttt gtttcaataa
     2641 agagaacact ttgttccaat atgcaaaaac acttcgttcc aatacgtaag aacactttgt
     2701 ttctacatat ccgaacactt tgtttctcta tactggaaca aagtgttcac cgttatgaac
     2761 taacagatta gctatatttg agaccggtga aaagcatatc cccgtgacac ctattccata
     2821 ctaaaaatcc cttgcagatg gctggcagga gaagtgtctg ccagctatct gcaagggaga
     2881 tttgcaagaa tgagctctct gtgtggagta cgcgttataa ttctatcact aatgattctc
     2941 tggggcccat cttcagctct tcaccgaagg tgatggcctt gccgctaaga atatcttttc
     3001 cctgcttgct gtttttcagg atttccttgt agaatttcaa aggaacggtg gtctctgcat
     3061 ctgtaccgtt cagcatcacg aatatcgtct tgccttcgta ctggcgtgcg taggcataaa
     3121 caccattctg taccatgaac tgcaccatgc tgcctttggc aatcacatcg tttcctttgc
     3181 gccagttcag gatggtcttg tagaagtcgt agcactcgtt ctgtattttg gtacgtccgg
     3241 ctggggtcag tgcgtttgtt gcgtcaccgg tccatccacc ggggaagtcc ttgcggacat
     3301 agccgtcgct cttgctcttc acgccattca tcataacttc cgttccgtag tagagttgcg
     3361 gaatgcggcg ggtggtaagc agcagggtag aggcttgctt cagcatcgga aggttgtcgc
     3421 cttcgcccag gaagcggtcg gtgtcgtggt tttcgatgaa tgccagtacg gaagcggggt
     3481 tggggtagag gaagtcgtat acgaagttat tgtatatgcg gtccagtccc ttgaaccaag
     3541 tttcggtctg ttcattcttg gcggtattta tcttgtcgaa gaagctgaag tccataacgg
     3601 tcttgaggtt actgttcttg ggggctgata gcttggaatc cttctgccac caggcggtgt
     3661 aggcgggttc ggtaacccag gtctcgccca cggtgttgta gttgggatat tcttcgttga
     3721 gctctttcat ccagttgctc atggcatcat agtcggcata cgggtaagtg tccatgcgga
     3781 tgccgtcgat gttggcgaat tcaatccacc agaaactgtt ctgtaccagg tagcggtaaa
     3841 cgtgagggtt cttctggttg aggtcgggca tggaaggtac gaaccagccg ttgttcatct
     3901 ggtcggcatc gtactgggaa gtataagggt ctacgtgcgg ggtcagtttg aaggaagtct
     3961 gcacgaagtt gttttcgtgg tcggggttgt tgaaccagtc tttggagggc atgtccttaa
     4021 tccatacatg ctctacaccg cagtggttga aaatcatgtc cattacgatt ttgatgccgc
     4081 gtgcatgggc tttttcaatc agctgcttgt attcttcgtt ggtaccgaag cgcgggtcca
     4141 ccttgtagta gtctgtggtg gcatagccgt gataggaacc gccggtcatg ttgttttcca
     4201 ggactggagt aaaccagagg gctgtgacgc cgaggtcgga gaagtagtcc agatgttgtt
     4261 cgatgccggc aaggtcaccg ccgtggcgtg cattggggtc attgcggtct accttgtaat
     4321 cggccatgcc cgcaatctgg tcattgtccg ggttgccatt ggcaaagcgg tcgggcatca
     4381 gcaggtacag tgcgtcggag gcgtcgaaac ctttatgttc gcaacctttc ttgttgcgtg
     4441 ccttcagttc atattccttt acgagtttct tttttccttc agtgaaggtg aggttgaatt
     4501 tgccgggttt tacatccttg tccagtttca gatagaccag gaggtagttg ttgctttcca
     4561 gcttgacggt gctgctcaat gagacgccgg gataattgac ggatactgcc gcgttgccga
     4621 tgccttcgcc atagaccatc agctggagtt ccgggttctg catgccggtg taccaaaacg
     4681 gagggtcgat tttgttcaca ttcatagctg catacgtact gagggagagt aagagtgttc
     4741 ccaagattaa gaatactttt ttcatgatag taactttacg gttaattttt gcgctaattt
     4801 aaaacaaata acggagaaag ttaatctttc tccgttactg taccttatta tattatgcaa
     4861 acgttttcat tggggctatt tgatgggggt tacgctggcg gtatcaacct ttcccttgaa
     4921 gaagtcctct ttcttgcgct tttctctgat gtccttcagc cagttttcgg cggcattgta
     4981 tcggttgtct tctccgatga tgggaactcc gtccgcatct acttcctgca ctttgtcctt
     5041 gctgtttttc ggacgggttt tcaggtaggc cgttaggtat ctctctgctt tggacgcatc
     5101 tttcagatag taataataga taaaggctgc gtcgtagagc agtttgtgtt tctgccggtc
     5161 gtatttttcg tattgtgtca gaagggtatt cgcctggtcg gtgtattgaa atgccatctt
     5221 gtagcagtcc gcaagcccca catataggcg ggacatgaca ctgtcgctgg gcatggcgag
     5281 gcttacggca gtttccagat aagtcactcc atcctctttc catgatgtct tggagcaggc
     5341 gcgtcccaga taatagagaa cgttgatgtt ggtattgtca tctttaagag ccctttccag
     5401 caggtcgtgt gctgggtaga agtcttcgag ggcataatag ctgattccgg cgtagaagca
     5461 ggtttggaaa gaactgtctt tttcctgtaa cagttgttca tatctttcta ttgctttggg
     5521 gtaatctttg ttcaggcaat aggcttgggc attgatgcgg ttcacaagga cgttggtgga
     5581 gtctatggaa cggtatatct ccgttatgtt tatggcgtct tcatactggt ggcctgctac
     5641 atagatgttg ccgagtttgg cagcagacag gtaatcattg ggatatcttt tctgtatgtc
     5701 caggtaggca tctatcacat gcatgatttc tgtgttgtca tagacttgcc ccatactttc
     5761 ggctctaagg tgtagtacat aggcggaact gtccctttct gccagcaggt tactttcctt
     5821 tagagactca cggtatctct tcatgttcat cagcagactg atatactgga tgcgtgcgta
     5881 tttattgtcc ggatttatgt ggagcgcatt ctggtagtaa tccagtgcct cgctatattt
     5941 ggcaagtgat ttgcagcatt cggcagcttc aatgtatgcc cggggattga gagaatcctg
     6001 agctacgact tcctgaaata cgctcagagc ttcaaggtta ttgcccagcc ctttcagcgc
     6061 tttccctttt tggtagagta gggggacggt cggggtttct tgatcgatca gcatcaaggc
     6121 tgtttcataa tcgtagttgg ccatcgcctc ttgaatggga tttgtggtct gtgccgccag
     6181 aagcgaacag catgcactga aacataagga gataaaaagc tttcgcatac agtatatcat
     6241 ttatatgagg ttaaactgac tgcaagttac taaaaagaat gtatttacga aataatcgta
     6301 atctgtttta gatagattaa cgaaaaagcc cctccaaaaa tgaaggggct ctaaaatagt
     6361 tcagaattca agccggataa cggaatgaat aaatgtatta cattaagaat cccagcagga
     6421 tacctgctgc tacagcggaa ccgattacac cggcaacgtt cgggcccatg gcatgcatca
     6481 gcagatagtt ggtaggatcg tattccagac ctactacttg ggagatacgt gcagagtcgg
     6541 gtacggcaga tacaccggca ttaccgatca acggattaat cttgttgccc ttcttcagga
     6601 agaggttgaa aatcttcacg aagatgacgc cggatgctgt ggcaatgaca aatgataagg
     6661 cgcccagacc gaatatcttg attgaatcaa gggttaagaa ctcggatgct tgcgtagaag
     6721 cacctactgt caaaccaagc agaatagtaa tggtatcaat cagtggacca ctggctgtgt
     6781 ttgccagacg acgtgtaact ccactttctt tcagtaaatt accgaagaac agcataccca
     6841 gcaaaggcag accggatggt acaaggaatg tggttagtaa caaaccgata atcgggaaca
     6901 ttactttttc cgtatgtgaa accacacggg gaggtttcat acggataaga cgttcatttt
     6961 tactggtcag ccaacgcata ataggcggct gtatcaccgg tactaatgcc atatatgaat
     7021 aggctgatac cgcaatggca cccattaagt taggagccag tttggaagag aggaagatgg
     7081 cagtcggacc atcggcacca ccaatgatac cgattgcacc agcctgcatc gggtcaaatc
     7141 ctatggcaag ggcaatcata taagcaccga atataccgaa ttgggctgct gcaccaacca
     7201 acattaattt ggggttcgat atcaaagcag agaaatccgt catggcaccg atacccagga
     7261 atatgagtgg cgggtaccaa ccggaggtta ctccctggta cagaatatta agtacggaac
     7321 cttcttcata gataccgact tttaatccgg cttccatatt gaaaggtata ttaccaatca
     7381 gcataccgaa accgatagga attaatagca tcggctcaaa ttccttggct acagccaagt
     7441 atatgaaaaa caaacctacc agaagcatta ccacatgtcc taccgttgca ttggcaaaac
     7501 ctgtataagt ccagaagtcg gcaaggttgt ttcctaaaaa tgtgataaat tctcccatat
     7561 tattcaataa ttacgaggtc agtaccttcg agaacagagt cccctttgtt tacattgatg
     7621 gctgtaatct taccgtcttt atcagcattg atattgtttt ccatcttcat ggcttccaaa
     7681 atgatgataa cttgtccctt ctttactgta tcgccgacat ttactttgat atcgaggatt
     7741 acaccgggaa gcggagattt tacacctgac ttgccggtag aagcagcggc cggttttact
     7801 accggagtag caggagcagc aggagcggat gtggctgccg gacgtgctac cggtttaacg
     7861 actaccttcg gtgctttttc catttcaact ttgtagggag taccgttcac ttctacgtga
     7921 gcgatgttgt cttcaatatc tccaatggca actttatata cgttaccgtt aattttatat
     7981 ttatattctt tcatcgtttt attttattat gggtgactta ctttttgtga ggagtctcac
     8041 gcaacgtata aatctttgaa ctccacggtg agtaactgcg ttttacacgg gtaatggtaa
     8101 gtatcgtgtc ttccacatcg tgtacatcgc tttggaattc gtgcatggcc attgaaatgg
     8161 cagcaaaaac ttctcccgga gcctgcccca gttgtttctc ttttgcttct tgtttatcag
     8221 taataccttt agctttcata gcattgcgtt tgctgaggtt aactgatatt ttacctataa
     8281 tcttgaagga gatgtagagt aatatcagcc cgcagaatac aacgctcatg gcagaaatag
     8341 ccataccgat acctacgctg tcatgctctt cgaatttttc catcttggca ttgctgtcga
     8401 tagtcttgtt gttggtactc ggagtgacat atttatcttc gcttccaccc tttacttccc
     8461 attggtcggc tgcatcactg acacgggcat aggattggtt ggcttttaaa gtaccggcag
     8521 gcactatgac ttgatcaagc aatttcttgc cggaatcata caacccaatc cagttggcat
     8581 ttgtggcatc cagtttgaag ttcgtatgaa atgtaccgcg tcttggttct ccatcagccc
     8641 agaaaagtgc atgctgacgt ggttttatga gtgtcagaac gtcacctttg ggaatgaaat
     8701 aactggcagt atcacccggc tggctgctga atttcagata gcaacctgca aggtcggcgc
     8761 tgccgtatga tctgttgaat atttcaatcc atgcgctgtg cacaccgtag tcatcctgat
     8821 agttgctttc gttgttgacc agcacttcat tcagcagcag tttgttgttc gatttctgtt
     8881 ctttgcaaga agagcaaaag cctaacacca gcatcaatga aaggaatatt ccgatttttg
     8941 ttttattcat aatcgttctt gttttagtgt gaaaagcttg attacaaggg aatattacca
     9001 tgcttcttag ccgggttagt caatttcttg gtttgcaact gttgcagggc acgaatgatg
     9061 cggaaacgtg tgttacgcgg ttcgataaca tcatcaatgt agccatattt agctgcatta
     9121 taaggattgg caaacaactt ggtgtattca gcctcttttt cagccaggaa ttgagccgga
     9181 ttttcctgct ctttggcttc gcgggcatat aatacttcta cagcacctgc accacccatt
     9241 acagcgattt cagcagtagg ccaagcataa ttcatgtcgc cacgcagctg cttacagctc
     9301 atcacgatgt gcgaaccacc gtaggattta cgcagtgtga tggtaacctt gggtacagta
     9361 gcttcaccgt atgcatacag cagtttggca ccgtgcagga tgacgccgtt gtactcctgg
     9421 ccggttcccg gaaggaatcc cggtacgtct accaatgata cgataggaat attgaaggcg
     9481 tcgcagaaac ggacgaagcg tgcgcccttg cgggatgcgt tgctgtcgag cacacctgcc
     9541 agatacttcg gctggttggc aacaatacct acggactgtc cgttgaaacg tgcgaaacca
     9601 ataatgatat tctttgaata atctttttgg atttcgagga actcaccatt atctatgata
     9661 gcgccaatta cctcgtacat atcgtacggt ttgttcgggt tatcaggaat gatatcgttc
     9721 agggaatctt ccagacggtc aatagggtct gtacagtcta catagggagc ttcttccaga
     9781 ttgttctggg gaatgtagct caacagtttg cggataaggg ccaaaccttc ttcttctgtc
     9841 tgtgcagtaa aatgagtaac accagatttg gtggagtgaa cgctcgcgcc acccaggttt
     9901 tcctggctta cgtcttctcc ggttacagtc tttactacct tcggaccggt aaggaacatg
     9961 taggatgtac cttccatcat caaagtaaag tctgtcaagg caggagagta aacggcgcca
    10021 ccagcacaag gaccgaaaat accggaaatc tgcggaatga cacccgaagc aagtatgtta
    10081 cgttggaaga tttcagcgta gccagccaag gcattaatac cttcctgaat acgtgcaccg
    10141 cccgagtcgt tgataccgat acacggagca cccattttca tggcttggtc cataatctta
    10201 cagattttca gagacatggt ttcggacagt gaaccggcag aaactgtgaa gtcctgtgcg
    10261 aagatataaa ccagacggcc ttcgattgta ccgcaaccgg ttactacacc gtcaccgggg
    10321 tagtgtttct tttccatgcc gaagttggtg catctatgtt ctacgaacat gtccatttct
    10381 tcgaaactgc cttcgtcgag aagcatggct atgcgctcgc gagctgtata tttacccttc
    10441 tcgtgttgct ttgcaatcgc tttttcacca ccaccgagac gtgctgcagc gcggcggtct
    10501 ataagctctt taatcttttc aagttgatta ctcatgaatt tatattcttt aagtgtttat
    10561 acaatttatg atttgatgat tttacagtct tgcttattcc ggtttctcgc aaagctcggt
    10621 caggacaccg agagttgact tcggatgcag gaatgcaatg ttcagacctt ctgcaccttt
    10681 gcggggagct ttgtctataa ggcggatacc tttttcttcg acttcggcaa gcgcaccggc
    10741 cactccgtct tcaacggcga atgcgagatg atgcatgcca ccgttaccgt tgttcttttc
    10801 gatgaacttg gcaattgtgc tttcgggaga agtaggttcc aacaattcga tctttacatc
    10861 gcccactttc aggaaagcgg ttctaacttt ctgatcttcc acggtttcga tgttgtagca
    10921 tttcaaacct aagacgtttt cgtagtacgg aagggcttct tcaatgctct taacggcaat
    10981 gcccagatgc tcaatgtgtg aaatcttcat aactatataa attaatgtta gtattgtatc
    11041 ctttttaata aaggtataaa gcagcacaaa gaaagagaat tcttccttaa taaagaaatt
    11101 tttcatcaat taattaatgg ttaattgaac tttagaagga ttttttcaga ctttagatag
    11161 agaccggttg ttttcttgat atcgttcgct aacggacatc cccactgtcc gaaaatgaac
    11221 acttacccct ctatgaaacc tttccggcca cttggcacac tctttgcttt tctgtttgcg
    11281 acaattttaa agattgaaca tgaaaaagaa tattttactt gcagtttgtt ttttgatgcc
    11341 gttggcaacc atggcgcaga atgatacttt gggacatgaa cgcaatatta cgctgtcgga
    11401 ggccattgta ctggcccgta cgcagtctgt ggatgctgct gtggcattga atgaattgaa
    11461 aaccgcgtat tgggaatacc gtacattccg tgcggacttg ttgccggaag tgaatttcac
    11521 cggtacacta cccaactata acaagtccta cagtacctac cagaattccg acggctccta
    11581 tagctttgtc cgcaacaata cactggggct gtccggacag ctttcggtag accagaacat
    11641 ttggtttacg gggggtaagc tgtcactgac ttcttcgctg gattatctca aacagctggg
    11701 ttccggggga gagaagcagt tcatgtcagt ccccgtgagc ctggagttga cgcagccggt
    11761 cttcggagtg aataccttga agtggaaccg ccgtatagag cccgtacgct atgccgaggc
    11821 aaaggccgag ttcatttcag ctacggaaga ggtgacgatg aaaaccatca cttatttctt
    11881 tgagttgctg ctggccaaag aatcgctcgc taccgccatg cagaacaaga cgaatgccga
    11941 ccgcctttat gaagtggcca tagccaaacg taaaatggga cagatatccg agaatgattt
    12001 gttgcagctt aaactgaatt cattgcaggg caaggccgac gtgactgagg cagagagcaa
    12061 cctgaatgca aaaatgttcc agctccgttc tttcctcggg gtgtccgagc aggaaagcct
    12121 gaatccggtg ttgcccgcca ctgttcccga tataaagatg gagtatgacc gtgtgctgaa
    12181 caaggcactg gaacgcaact cctttgcaca gaacattcgc cgccgccagc tcgaagctga
    12241 ttatgaagtg gcaacggcac gcggaaactt gcgcagcatc gacctctttg ccagtgtggg
    12301 ctatacgggg cagaaccatg aattctcttc agcctaccgg gacttgcttg ataatcagat
    12361 tgtgcaggta ggcgtcaaga ttcctatcct tgactggggc aagcgccgcg gcaaggtaag
    12421 agtggcaaag agcaaccgtg aagtggtctt gtccagaatc cgtcaggaac agatggactt
    12481 taatcaggac atctttttgc tggtggctaa c
//
