LOCUS       c00051_gnlPro..        14443 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CIDLEMKA_51.
ACCESSION   c00051_gnlPro..
VERSION     c00051_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 05:54:59
            Original ID  :: gnl|Prokka|CIDLEMKA_51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2008
            Orig. end    :: 16451
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14443
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[12008:16450]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14442
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14443
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14443
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             151..1206
                     /locus_tag="ctg51_4"
                     /transl_table=11
                     /translation="MSQIPSLISDLAVILISAGLVTLLFKKLKQPVVLGYIVAGILAGP
                     AIKEIPTVTDVESIRIWADIGVVFLLFALGLDFSFKKLMKVGGTAVIGAVTVVIGMMTF
                     GYITGLSLGWGHMNSLFLGGMLSMSSTTIIFKAFDDMGLRNQRFAGVVFGILVVEDLFA
                     VLLMVLLSTLAVSKHVEGMELLDSVIKLGVFLLFCFVVGIYLIPSFLKRARTFLNDETL
                     LIVSIGLCLGMVMIATKAGFSSALGAFVMGSILAETIDAEHIEHIVKPVKDLFGAIFFV
                     SVGMLIDPVLLWEYKIPILILTLVVMVGQILFXXXXSAYYYRDRLSKSPSSPVSRWHKS
                     VSSPLSSPLWD"
     CDS             1284..1904
                     /locus_tag="ctg51_5"
                     /transl_table=11
                     /translation="MIRMAEPAYKIAERVIPASWMSFLERYSSGSNTIRQKSAWDKLLK
                     ALVRIVGTYTAVTLVLIFIWLQFVAPFMINQLPGLQGQIISLVLILLLISPMLRAIMMK
                     KNHSVEYQQLWHDSKYNRGPLVSLIVLRIILCIGLVMLPIARLLNTAVGIGLAIAATVI
                     ALVIFSKRLKKQSILMERHFFTNLTARELENERNAPITWLILK"
     CDS             1922..2377
                     /locus_tag="ctg51_6"
                     /transl_table=11
                     /translation="MGKTLKELNFRQKCNVNIVTIIRGSKRINIPGGNERLYPFDKLVV
                     VGADDDLAHFRQYIEERYKESLNNLQETKEVNMEQFFISEGSGLIGRTILESGIRDNSG
                     CLVIGIERDARSIKNPPPTTVFEQGDIVWIVGEHEKVLRLSEGKTVK"
     CDS             2406..3164
                     /locus_tag="ctg51_7"
                     /transl_table=11
                     /translation="MKFIGIIPARYASTRFPGKPLADMAGRPMIQRVYEQVKDVLDTVC
                     VATDDSRIEAAVKAFGGNVVMTSDQHRSGTDRVYEAYTKVGQGYDVVVNIQGDEPFIHP
                     EQIETLKACFTDVGTQIATLVKPFRPDDDFETTLFNANSPKVVLNKNNEAMYFSRSIIP
                     YMRGKNYQEWLPNHTYYKHIGLYAYRADTLKEITHLPQSPLELAESLEQLRWLENGYKI
                     KVGITQQETIGIDTPEDMEKALAFLSQQHG"
     CDS             complement(3145..3831)
                     /locus_tag="ctg51_8"
                     /transl_table=11
                     /translation="MRXXXWLACSMAKVLTSLFVPVGGGAVLITAVLMLEWWASLFILR
                     KFNVGDMAPLYALFPVVMEWGTYCSPYYHLNSILSLVIVLYIFCGYIQIKVKWLSWVTG
                     FILLFAVYCMVGSRLFIFVILVLLYXXXXEIGEKHWVYWALLLITGTVLPEFLKELYSL
                     SEEQAYQYPQAWLPAFFPAIMLACVLVATQFKKVRYMQISVWSVSVTSGLLLVLLALTA
                     FSHAVG"
     CDS             complement(4169..6067)
                     /locus_tag="ctg51_9"
                     /transl_table=11
                     /translation="MDKNTLIGFLLIGIVLFAFSWFNKPTPEQLEAQRRYQDSIAQIEL
                     AKQAELQREDSKSTADNSFDSLPDSARDARLKSSFGVFAEAMTGTDDVTVLENDLIELH
                     ISNKGGRISYARLKDYTTYDDKPVILFEGKEASLDFTLVTATNRVLNTADLYFTPVKTQ
                     DPNRLVMRLNTGEGSSLDFIYTVKPDDYMVQFDIKGTGLNGVLAPSTTALDMVWRQKIR
                     QQEQGIKYENRYTALYYKFLSDDVEQLSESKSEDKKVSGRLKWIAYKDKFFSTVMIADE
                     GFESATFDSKMVEADGIVKEFKTTTAVPFDLRGNEATTFRYFFGPNSYPLLKSYDKGVA
                     SDQQLDLERLVPLGASVFRWVNQYFVIPMFDFLGKYIKSYGLIILLMTIIVKLILFPLT
                     YKSYMSSAKMRVLRPQVEELNAKYPGQDKAVERQRATMELYSRAGASPMAGCIPMLLQM
                     PILIALFMFFPSAIELRHQSFLWAHDLSTYDAIFSWNKYIPIITPYFGNHISLFCLLMT
                     ITNVIYTKYNMEMTNTGQQQMPGMKAMMYMMPLMFLVFFNQYASGLTYYYFISTLITIV
                     QTLVFRYTINEDKLLAKLEANKKKPQKKSGFMKRLEEAQRMQQEQLKKQQDQKKKR"
     CDS             complement(6079..7683)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg51_10"
                     /sec_met_domain="GATase (E-value: 2.5e-55, bitscore: 177.3,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VADTKYIFVTGGVVSSLGKGIIAASLGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVPTTRSNNITTGRIYQSVINKE
                     RKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQL
                     KWELGKNCMCVHLTYVPYIAAAKEFKTKPTQHSVKQLQELGIQPDVLVLRTEHLLSNDI
                     TRKVALFCNVDADAVVQSVDVPTIYEVPLVLQRQNMDVTILKKMGLEVGPTPEMKPWKE
                     FLKKKTDATETVKIGLVGKYVELQDAYKSIDESLLQAAIYNDRKLDLHLFHSEKLTEAN
                     AAEQLKDMDGILIAPGFGQRGIEGKFAALKYARENDVPCLGICLGMQCMVIEFARDVLG
                     MTDANSTEMEPNTPFKVIDLMEEQKNITNMGGSMRLGAYDCILKKGSKAYEAYGKEHIQ
                     ERHRHRFEFNSQYREQFEEAGMKCAGENPETGLVEVVEIPALKWFVGVQFHPEYNSTVV
                     NPNPLFVSFVKAAIDNK"
     CDS             7915..9444
                     /locus_tag="ctg51_11"
                     /transl_table=11
                     /translation="MVIKRYFILFSILSLLTNLANAQEVTTITGTNLKDTVQSNAADTI
                     PMIEIEDLDLDNIISLRAQFEKQNQSYSAPVTPNENLLRFLKKDEVELSDEAMYWARLV
                     RDASTIFDANMTFQDTVIADPLFLPLIFKGKLLPKDLSFYDEDAWKNKIDIPQPFLQDT
                     IFKEEVFRQQFREKAQRNIEANHPEYFRYSMRDLPQDKVVAKVIRKPTYQPDLIKVESE
                     ADFSDVDAPVKFIPERRYWTSHFESSLQFAQNYISPNWHKGGVSTLNLTNRELFTYNYN
                     KEKIKFDNSLEIKNNLYTAPKDTLRDYKVGDDVFRIYSNFGYKAFNKWYYTLDLDFKTQ
                     LFSSYAENQNVKLAGLLSPFSINFGLGMKYDLDKTFASSKHKKVTLSANLAPLSYTYVR
                     TLDKDIDLGRHFQKRDGEEEFPYKQSLFGSTVNATMTFQFSRNIIWYSRFYYMTDYKRI
                     QGEFENRLNMAISRFFSTIISLNLRYDDGISKXXXXPSMKTSTATYRLTSC"
     CDS             9572..9991
                     /locus_tag="ctg51_12"
                     /transl_table=11
                     /translation="MSESINHNGIIEKIDGNAVFVRIIQQSACSGCHAQSMCSASEKKE
                     KIIEVNDNNPGRFHVNEEVTLCGQSSLGLQAVFLAFVLPLIVVVAAIVAGSCLQWDETT
                     SGLTGLLLLVPYYSILYFLREKLKRKFIFTLKKLN"
     CDS             10001..10780
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_13"
                     /sec_met_domain="Fer4 (E-value: 8.6e-12, bitscore: 34.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.1e-09, bitscore: 28.3,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 8.7e-11, bitscore: 31.6,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1e-06, bitscore: 19.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAIGAVFLYAASKKFEVYEDPRIAEVQEALPGA
                     NCGGCGYPGCGGFAAACVKADSLEGLLCPVGGAETMGKVASILGMEAATAEPMVAVVRC
                     NGTCQARPRTNQYDGVKSCAIASSLYGGETNCTFGCLGYGDCESACTFDAIHVNLTTGL
                     PEVDEDKCTSCGACVKACPKNIIELRKKGPKSRRIFVSCVNKDKGAAARKACANACIGC
                     GKCVKECPFXXXXSKQSRSKTTWLISTTANAVCAVNA"
     CDS             10993..12324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_14"
                     /sec_met_domain="Fer4_10 (E-value: 2.8e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.3e-17, bitscore: 52.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7.7e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.7e-32, bitscore: 100.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDTSGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVTNPSNFLVRMGTPISALIEAAGGVPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             12337..13296
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_15"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 9.9e-120,
                     bitscore: 389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVIACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLLGKMGGSLGEVSALALLLGLVFILWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             13329..13934
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_16"
                     /sec_met_domain="FMN_bind (E-value: 4.1e-25, bitscore:
                     78.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FDNKPSEDAYMAVTGDGDSLKIYPATKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSAGPLKVTKDGGNVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             13927..14442
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg51_17"
                     /sec_met_domain="Rnf-Nqr (E-value: 4.8e-68, bitscore:
                     218.7, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGLGMGLGFTLALTLLGATRELLGTGKLFGLTLMP
                     EQYGSLIFV"
ORIGIN
        1 tcgctcactt cgaacttaaa atcgagttgt tgatgctcgc cctgttcaat caatgcttct
       61 atcggatgtt tcttcttcat tttggctcat tatttgacct gcaaaattaa aataaatgtc
      121 taactttgcc aaccgaaaaa gagtgaaagc atgtcacaga tcccttcatt aatttcagac
      181 ctggcagtaa tactgatttc tgcggggctt gttactttgc ttttcaagaa attaaagcaa
      241 ccggtcgtac ttggctatat tgttgccgga attctggcag gaccagccat taaagaaatc
      301 cctaccgtta cagacgtaga aagtatccgt atctgggccg acatcggtgt cgtattcctg
      361 ctttttgccc tgggactgga cttcagtttt aagaaactga tgaaagtcgg aggcaccgcc
      421 gttatcggag cagtcaccgt cgttatcggg atgatgacgt tcggctatat caccggattg
      481 tcgctcggct gggggcacat gaatagtctt ttcctgggcg gaatgctttc catgtcgtcc
      541 acgacaatca tattcaaggc tttcgacgat atggggctgc gcaaccaacg gtttgccgga
      601 gtggtgttcg ggatattagt ggtggaagac ttatttgctg tcctgctgat ggttttgctt
      661 tccacacttg ccgtcagtaa acatgtcgaa gggatggagt tgctcgacag cgtgatcaaa
      721 ctgggggtat tcctgctctt ctgttttgta gtaggtattt accttattcc ttctttcctg
      781 aaaagagcac ggactttcct caatgacgaa accctgctga tcgtcagtat cggcctatgc
      841 ctggggatgg tcatgatcgc gactaaagcc ggattttctt ctgcacttgg cgctttcgtg
      901 atggggtcta tccttgctga gacaatcgat gcggaacata tagaacatat cgtaaaaccg
      961 gtaaaagact tgttcggagc cattttcttc gtttctgtcg gcatgctgat cgacccggta
     1021 ttactttggg aatacaaaat accgatcctg atactgacac ttgtcgtcat ggtcggacag
     1081 atactttttn nnnnnnnnnc ttcggcgtac tattatcggg acagactgtc aaagtcgcca
     1141 tccagtccgg tttctcgctg gcacaaatcg gtgagttcgc ctttatcatc gcctctttgg
     1201 gactgacgct caaagtaacg gataatttcc tttacccgat cgttgtggcc gtatctgtca
     1261 taacaacctt ttttacgccc tatatgatac gtatggccga accggcttat aaaatagctg
     1321 aacgagtcat cccggcaagc tggatgagtt ttctggaacg ttattcttct ggctccaaca
     1381 cgatccggca gaaaagtgcc tgggacaaac tgctgaaagc attggtgcgt atcgtcggca
     1441 cctatacggc tgtcacgctg gtactgatct ttatctggtt gcaattcgtc gctccgttca
     1501 tgatcaatca gctaccggga ctgcaaggac aaatcatttc cctggttctg atccttctcc
     1561 taatctcacc gatgctgcgt gccatcatga tgaaaaagaa ccattccgta gaataccaac
     1621 aattgtggca cgacagcaaa tataaccgtg gtccgttggt ttccctgatt gtgctccgta
     1681 ttatattatg tatagggctc gtcatgctgc cgatcgcacg cctgctgaac actgctgtcg
     1741 gaatagggct cgccatcgca gccaccgtca tagccctggt tatcttctct aagcggttga
     1801 agaagcagtc gatcctgatg gaacgccatt tcttcacaaa cctgacggca cgtgaactgg
     1861 agaacgaacg aaacgctccc atcacctggc tgattttgaa gtgaagcaaa actcccccag
     1921 tatgggcaag acactcaaag aacttaattt caggcagaaa tgtaatgtga acatcgttac
     1981 tattatccgg ggaagcaagc gtatcaacat accgggagga aacgaacggc tttatccgtt
     2041 tgataagctg gtcgtagtcg gtgcggatga cgacctggcc catttccgtc aatacataga
     2101 ggagcgttat aaagaatcgc tgaataacct ccaggagact aaagaggtga atatggaaca
     2161 attctttatc agtgaaggct ccggacttat cggccggact atccttgaat ccggaatacg
     2221 cgataactcc ggctgcctgg tgatcggtat cgaacgagat gcccgttcaa tcaaaaaccc
     2281 gcctccaaca accgtattcg agcagggaga tattgtatgg atcgtcggcg aacatgagaa
     2341 agtgcttcgt ctcagtgagg gtaaaacagt aaaataatta actaacgaat aaaaacaacc
     2401 ggagtatgaa gtttatagga ataataccgg caagatatgc ctccacccgc ttcccgggga
     2461 aacctttggc cgacatggcc ggcaggccca tgatacagcg tgtgtatgaa caagtgaagg
     2521 atgtactgga taccgtttgt gtagccaccg acgatagccg tatcgaagct gccgtgaaag
     2581 cattcggcgg aaatgtcgtt atgacttccg accagcaccg gagtggcacc gaccgtgttt
     2641 acgaagccta cactaaagtt ggacaaggat acgatgtcgt tgtcaatatc cagggagacg
     2701 aacctttcat ccatccggaa cagatcgaga cgttaaaagc atgttttact gatgtcggca
     2761 cgcagattgc cacactggta aaaccattcc gtccggacga tgacttcgaa acgacattat
     2821 tcaatgcaaa ctcaccgaaa gtagttctca acaagaataa cgaagcaatg tatttcagcc
     2881 gttccatcat tccttatatg cgcggcaaaa attaccagga atggttaccc aaccatacgt
     2941 attacaaaca tatcggtttg tatgcttacc gggccgatac gctgaaagaa atcacccacc
     3001 tgccccaatc accactggag cttgccgaaa gcctggaaca actcagatgg ctcgaaaacg
     3061 gctacaagat aaaagtcggc atcacccagc aggagacaat cggtatcgac acgcctgaag
     3121 acatggagaa agcacttgct tttctcagcc aacagcatgg ctgaacgcag taagcgccag
     3181 caataccagt aaaagtccgg aagtgacaga tacagaccat acactgatct gcatataccg
     3241 gactttctta aactgcgtag ccaccaacac acaagccagc atgatagccg ggaaaaatgc
     3301 cggaagccat gcctgtggat attgatatgc ctgttcttct gaaagtgagt acagttcttt
     3361 caggaattca ggcagcacag tacccgttat caacagcaaa gcccaataca cccaatgctt
     3421 ctctcctatt tcnnnnnnnn nntcgtacaa cagcacaagg attacaaaaa taaacaaccg
     3481 gctccccacc atacaataaa ccgcaaacaa caaaataaac cccgtcaccc aagagagcca
     3541 ttttaccttt atctgtatat aaccacaaaa tatatacaaa acaataacca aagaaagaat
     3601 agaattcaaa tgataataag gactacaata ggttccccac tccataacaa ccggaaacag
     3661 agcatacaaa ggagccatat cccctacatt gaatttccgc agaataaata aagaagccca
     3721 ccattccagc atcaacacgg ccgtaatcaa aacagccccg ccaccgacag gaacaaacaa
     3781 agacgtaagt actttcgcca ttgaacaagc cagccannnn nnnnnncgca tagcaatgca
     3841 aagagtccag ctaccctctt ttgcaaaagc ttttctttct tatccatcag tgaactattt
     3901 ttatacctat taaactcaaa acgtaaagcc ggtacttgct attccgaccg gataagtcgt
     3961 caacgtaagc ataatcatca atagttgact tatatatcaa tagtgcaaat atataaatat
     4021 tttaatacaa cgcacaccac atttcttcaa attcaagcga ttgtacaaaa tatacaactt
     4081 attgcataat ccggacacaa aaaaaggcgt gcctgagtct tttccggacc ggcacgcctc
     4141 tcttttattt atcttgcaga aaaagctgtt atcttttctt tttctgatcc tgttgtttct
     4201 tcaactgctc ctgctgcata cgctgcgctt cttccagacg tttcatgaaa cctgatttct
     4261 tctgaggctt cttcttgttg gcttccagct tagccagcag cttatcttca ttaatcgtat
     4321 aacggaacac caatgtctga acaatcgtga tcagcgtaga aatgaagtaa tagtaagtca
     4381 gacccgatgc atactggttg aagaatacca ggaacatcag cggcatcata tacatcatcg
     4441 ccttcatacc cggcatctgt tgctgtccgg tattggtcat ttccatatta tacttggtat
     4501 agataacgtt ggtgattgtc atcagcagac agaacaaact gatgtggtta ccaaaatacg
     4561 gagtgataat aggaatgtat ttgttccaac tgaaaatagc atcgtatgtt gacaaatcgt
     4621 gcgcccaaag gaaactctgg tgacgcagtt cgattgccga cgggaagaac atgaacaagg
     4681 cgatcaaaat cggcatctgc aacagcatcg ggatacaacc tgccatcggg cttgccccgg
     4741 ctcggctata caattccata gttgcacgct ggcgttccac cgctttatcc tgtcccggat
     4801 atttggcatt aagctcttcc acctgcggac gaagcacacg catcttcgct gacgacatat
     4861 atgatttata tgtcaacggg aataaaatca gtttcacgat aatcgtcatc aacaggatga
     4921 tcagaccgta actcttgata tatttaccca ggaagtcaaa catcggaatg acgaaatact
     4981 ggttcaccca acggaagaca ctggcaccca gcggaaccaa acgttccaga tccaactgct
     5041 ggtccgaagc aacccctttg tcatacgatt tcagcaacgg atagctgttc ggtccgaaga
     5101 aataacggaa agtcgttgcc tcattgcctc tcaggtcgaa aggaacggct gttgtagtct
     5161 taaactcttt aacgataccg tctgcctcaa ccatctttga atcgaaagta gcgctttcaa
     5221 aaccttcatc ggcaatcatc accgtcgaga agaatttatc tttataagca atccatttca
     5281 gacggcccga caccttcttg tcttcgctct tgctttcgct cagctgctcc acatcatcgg
     5341 acaggaattt ataatacaag gcagtatatc tgttttcata tttgataccc tgttcctgct
     5401 ggcggatttt ctgacgccat accatatcca aagcagtcgt actcggagcc aggacaccgt
     5461 tcaggcccgt tcccttaata tcgaactgaa ccatataatc gtccggcttg actgtataga
     5521 taaagtccag tgaactgcct tcacctgtat tcagtcgcat caccaaccgg ttcgggtcct
     5581 gtgttttcac cggagtgaaa tacaggtcgg ctgtgttcaa tacgcggttg gttgctgtta
     5641 ccagggtaaa gtcaagcgaa gcctcttttc cttcaaacag gatgaccggc ttatcatcat
     5701 atgttgtata atccttcagg cgggcatatg aaatacgtcc tcccttatta ctgatatgca
     5761 gttcgatcag atcattttcc aaaacagtta catcatctgt acctgtcatt gcttcagcga
     5821 atacaccgaa actgctcttc agccgggcat ctctcgcaga atccggcaag ctatcaaaag
     5881 aattatcggc agtgcttttg ctgtcttcgc gttgcaactc cgcctgttta gccagttcga
     5941 tctgagcgat cgagtcctga taacggcgct gggcttccaa ctgctcaggc gtcggtttgt
     6001 taaaccagct gaatgcaaat aaaacaatac caataagcag aaaaccaatt aatgtgtttt
     6061 tatccatcta taacgttgtt atttattatc aatagcggct ttcacaaagc tcacgaaaag
     6121 tgggttcgga ttaactaccg tactgttgta ttccggatgg aactgaacac caacgaacca
     6181 tttcaacgca ggaatttcta ccacttccac cagaccggtt tccggattct cgcctgcaca
     6241 tttcatgccg gcttcttcaa actgttcgcg atactggctg ttgaattcga aacggtgacg
     6301 gtgacgttcc tggatatgtt cttttccata agcctcatag gctttggaac ctttcttcag
     6361 gatacagtcg taagctccca gacgcataga acctcccata ttggtaatgt tcttctgttc
     6421 ttccatcagg tcgatcacct taaacggcgt attcggctcc atctcggtcg aattggcatc
     6481 cgtcataccc aaaacgtcgc gggcaaattc aatcaccata cattgcatac ccaggcagat
     6541 acccaggcaa ggcacatcgt tttcgcgggc atatttcaag gcagcgaact ttccttcgat
     6601 accgcgctgt ccgaatcccg gagcaatcag gataccatcc atgtccttca actgttcagc
     6661 cgcattggct tcagtcagtt tttccgaatg gaacaaatga agatccagtt tgcggtcgtt
     6721 gtagatagca gcctgcaaca atgattcgtc gattgactta taagcatcct gtaattccac
     6781 atatttacca accagaccga tcttaactgt ttcggtagca tccgtctttt tcttcaggaa
     6841 ctctttccag ggtttcattt ccggagtcgg ccctacttcc aatcccatct ttttcaggat
     6901 agttacatcc atgttctgac gctgcaatac cagcggaact tcataaatag taggaacgtc
     6961 gaccgactgc actacagcgt cggcgtctac gttacagaac aaagcaacct tgcgggtaat
     7021 atcattactc agcaaatgtt cagttctcaa gaccagtaca tccggctgga tacccagttc
     7081 ctgcaactgt tttacagaat gctgtgtagg tttcgtttta aattctttcg cagctgcgat
     7141 ataaggtaca taagtaagat gtacgcacat acagttctta cccagttccc atttcagctg
     7201 gcgaacgctt tcgatgaaag gcagcgattc gatatcgcct actgttccac cgatttccgt
     7261 gatcacaaag tcaaacttgt acttcgatcc cagcagcttc acatttctct tgatctcgtc
     7321 ggtgatatga ggaacaacct gcacagtctt gcccagataa tcgcccttgc gttccttatt
     7381 tatcacactc tgataaatac gacctgtcgt aatattgttc gagcgtgtag tcggaacatt
     7441 caggaaacgt tcataatgtc ccaggtccag gtccgcttca tgtccgtcta cggttacata
     7501 acattcaccg tgctcataag ggttcaatgt acccggatcg atattaatgt aggggtcaaa
     7561 cttttggata gtaaccttgt aacctctcgc ctgaaggagt ttacccaatg atgcagcaat
     7621 aattccctta cctaaagaag agactacgcc gcccgtaacg aagatgtact ttgtatctgc
     7681 cacgatagta atattttaat tgtctttaat tgctcactcg catttcaaaa ctgcaaagtt
     7741 agtcattttc attcagacag caagtgtctc ggatattttt tcaaagcaca ttcatccgca
     7801 ttccggtttc cctattagtt cagattgtta tatgatgtga aagattagta gatttcatac
     7861 tttttatcta atttcgcacc gtagatactt atagattgta aataaaaagg aattatggtt
     7921 atcaagagat acttcattct attttctata ctttcattat tgacaaacct ggcaaatgca
     7981 caggaagtga caactattac cggaaccaat cttaaagata cagtacagag taatgcggct
     8041 gatactatcc caatgattga aatcgaagat ctggacctgg ataatatcat aagcctgcgg
     8101 gcacaattcg agaaacaaaa ccagtcatat tcagcaccgg tcacaccgaa tgaaaatctg
     8161 cttcgcttcc tgaaaaaaga cgaagtggaa ctgtcggacg aagccatgta ctgggcacgt
     8221 ctggtgcgcg atgcttccac tatcttcgac gcgaatatga catttcagga tacagtcata
     8281 gcagacccgc tgtttttacc gctcatattc aaagggaaac tccttccgaa agatctttcc
     8341 ttctacgatg aagatgcatg gaaaaataaa atcgatatcc cgcaaccttt tcttcaggac
     8401 accatattta aagaagaggt gttcagacag cagttccgcg agaaagcaca aagaaatata
     8461 gaagccaacc atcctgaata tttccgttat tcaatgaggg atctacctca ggacaaagta
     8521 gttgccaaag tgatcagaaa gccgacctac caaccggacc tgatcaaggt agaaagcgaa
     8581 gcagacttca gtgacgtgga tgcaccggta aaattcattc ccgaaagacg ttactggacg
     8641 tcacatttcg aaagttcttt acagtttgct cagaattaca tctctccgaa ctggcataaa
     8701 gggggtgtaa gtacgctgaa cctgaccaac cgcgaactgt ttacatataa ttataataag
     8761 gaaaagataa agttcgacaa ttcactggaa ataaagaaca acctgtatac cgctcccaaa
     8821 gatactttgc gcgattacaa agtcggagat gacgtgttcc gtatctacag taactttggt
     8881 tataaggcat tcaacaaatg gtactacaca ctggatcttg acttcaaaac ccagcttttc
     8941 agcagttatg ccgaaaacca gaacgttaaa ctggccggac tgctctcacc tttcagtatt
     9001 aatttcggtc ttggtatgaa atatgacctg gataaaacgt tcgcgtcgtc caaacacaaa
     9061 aaagtaacgt taagtgccaa ccttgcaccg ttatcttata cgtacgttcg tacattagat
     9121 aaagacatcg acctgggccg gcatttccag aagagagacg gagaagaaga gtttccttac
     9181 aaacaaagcc tgttcggttc taccgtcaac gcaactatga cattccagtt cagccggaat
     9241 atcatctggt attcgcgttt ctattacatg acagattata agcgtatcca aggtgagttc
     9301 gaaaaccgtc tgaatatggc aataagtcga ttcttctcga ctatcatctc gctgaactta
     9361 cgttatgatg atggtatctc caagnnnnnn nnnnctccaa gcatgaagac ttcgacagct
     9421 acttacagat taacgagttg ttgagctttg gctttaatta caaatggtaa gctgaacacg
     9481 attatttctg taataaactt tgttaatcgt gacataatat ccaaataatc cttacttttg
     9541 cccctgattt tgcaatgtcg agattacaaa catgagtgaa agtatcaatc acaacggaat
     9601 aatagagaag atcgatggca atgcggtctt tgtcagaatc attcaacaat cggcctgctc
     9661 cggttgccac gcacaaagca tgtgcagcgc atctgaaaag aaggaaaaga tcattgaagt
     9721 gaacgacaat aaccccggca gattccatgt gaacgaagaa gtaaccctat gtggccagag
     9781 ttcgctcggc ctgcaagcgg tttttctggc ctttgtgctt cctctgattg ttgtagttgc
     9841 ggcgattgta gcaggaagct gtttgcaatg ggacgaaaca accagcgggt taaccggtct
     9901 attactacta gttccctact acagtatatt atacttttta cgcgagaaac tgaaaagaaa
     9961 atttatattt accttgaaaa aacttaattg atcaaatatc atgattttaa ttgccgttat
    10021 ttcattagga gccattggag ccatcggcgc agtattcctc tacgccgcct ccaagaagtt
    10081 tgaagtatac gaagatcctc gtatcgcaga ggtccaggag gcattgcccg gagccaactg
    10141 cggaggttgc ggttaccccg gttgcggtgg ttttgcagca gcctgtgtaa aggccgattc
    10201 actggaagga ctgctttgtc cggtcggtgg cgccgaaaca atgggtaagg tcgcatccat
    10261 cctcggtatg gaagctgcta cagccgaacc aatggtagca gttgtccgtt gcaacggaac
    10321 ctgccaggcc cgtccgcgca ccaaccagta tgatggcgta aaaagctgtg ccatagcatc
    10381 ctctttgtac ggaggcgaaa cgaactgtac gttcggttgc ctgggttacg gcgactgcga
    10441 aagtgcctgt accttcgacg ccatccacgt caatctgaca accggactgc cggaagtgga
    10501 cgaggacaaa tgtacttcat gcggagcctg cgtcaaagct tgtccgaaaa acattatcga
    10561 actgcgcaaa aagggaccga aatcacgccg tatcttcgtc agctgcgtaa acaaagacaa
    10621 aggagctgct gcccgtaaag catgtgcgaa cgcttgtatc ggttgtggta aatgtgtgaa
    10681 agaatgtccg ttcgannnnn nnnnntcgaa gcaatcacgc tcgaaaacaa cgtggcttat
    10741 atcgactacc gcaaatgccg tctgtgccgt aaatgcgtag cagtatgtcc gaccggagca
    10801 attcacgaat tgaactttcc gccccgtaaa gaagcctccc ctgctgtgga cgccgacaaa
    10861 gtaaagccag taacgcctaa agctgcaccg gcccttaaag ccgaagcacc gacaaaagtc
    10921 gaagttacac cggcaacagc gcctgaaaca ataacaaaag aagaaacaac tcaaaaataa
    10981 aaatctaata gtatgctaag gacatttcga atcggaggta tacatccacc cgaaaataaa
    11041 ttgtctgccg ggaagaaaat aaccggactg gctataccca agcaggttat tataccgcta
    11101 agccagcata tcggggctcc tgcccaggct gtggtaaaga agggtgatac ggttaaagta
    11161 ggtacgcttc tcgccaaagc cggaggtttt gtatcggcga atatccactc gtcggtatcc
    11221 ggtaaagtaa acaagataga taacgctctc gacacaagcg gatacaaacg tcccgctatc
    11281 tatattgatg tggaaggtga cgaatgggaa gagtcgatcg accgcagcga aacgctcgtg
    11341 aaagagtgcc cgcttccttc caaagagatc gtagacaaga tcgccgcagc cggtatcgtg
    11401 ggtctgggtg gtgcgacatt ccccacacag gtcaaactga tgccgcctcc cggaagcaaa
    11461 gccgagatca tcattatcaa tgccgtagaa tgtgagccgt atctgacttc cgaccattca
    11521 ttgatgatgg agaaggcaga gcagattctg gtcggcgtta cgctgttgat gaaagctgta
    11581 aatgtaacaa aagcagtgat cggtatcgaa aacaacaagc ctgacgccat cgctcatctg
    11641 agtaaactgg ctacagccta taaaggtatc gagattatgc cgctgaaagt acagtatccg
    11701 caaggaggtg aaaagcaatt aatcgacgct gtgattcgcc gtcaggtgaa gagcggtgca
    11761 ctgcctattt ccgccggagc tgtagtacaa aatgtaggaa ctgcttttgc agtgtatgaa
    11821 gcggtaatga aaaacaaacc tttgtttgaa cgcgtcgtta ccgtgacagg taaagcagtt
    11881 accaatcctt ccaacttcct ggtccgtatg ggtacgccta tcagtgcact gattgaagct
    11941 gccggtggtg ttcctgaaaa tacaggaaag ataatcggtg gcggcccgat gatgggaaaa
    12001 gccctgattg ctccggaagt accggtaacg aaaggtagtt caggcgtatt gctcctgaca
    12061 aaagaagagt ctgtccgcaa accgatgcgc gactgtatcc gctgtgccaa atgtgtcagc
    12121 gtttgtccga tgggcctcaa ccctaccctg ctgatgaatg caacagaatt tgcagaatgg
    12181 gatttggccg agaagaatta tatcaccgac tgtatcgagt gcggttcttg tagttatacc
    12241 tgcccggcca accgtccgtt gctggattat atccgttcgg gtaaaggaaa ggtaatgggt
    12301 atcatacggg cacgaaagtc ataaaaacag agcaatatgg aaaataattt aatagtatct
    12361 ccttcgcccc atatccacgg cggcgatagc ataagcaaaa atatgtatgg tgtactgatt
    12421 gcccttgttc cggctttcct ggtatccctc tactacttcg ggctgggtgc gctgatcgtt
    12481 actgcaacat cggtcatagc ctgcgtcctc tttgaatatc tgatccagaa gttcctgatg
    12541 aaaaaggaac cgaccgtatg tgacggttcg gctatcctga ccggtgtact gctggcattc
    12601 aacctgccgt cgaacctgcc tgtatggatc atcctgatcg gtgcactggc agcaatcggt
    12661 atcggtaaga tgtcgttcgg cggactgggt aacaatattt ttaacccggc attagtcgga
    12721 cgtgtattcc tgctgatctc tttcccggca cagatgacga tgtggccgga agtcggacag
    12781 ctgacagcct acaccgacgc aaccaccggt gcaactgttt tatcactgat gaacgaaggg
    12841 gcactcgaca agttgcctac cctggtagat atgttgttag gtaaaatggg cggcagcctt
    12901 ggtgaagtaa gtgcactggc attgctgctg ggactcgtct ttatattatg gaaaaagatt
    12961 attacctggc agattccggt ttctatcctg ctgaccgtat ttgtattcac aggtattatg
    13021 cacctggtta atccggtaca atacgcaagt ccgttcgttc acctgctgtc gggaggtctg
    13081 atgctgggag ccatctttat ggcaaccgac tatgtgactt cgcccatgag taagaacggt
    13141 atgctggttt acggtgtcgg tatcggtatt ctgaccaccg ttatccgtct gtttggttct
    13201 tatccggaag gtatgtcgtt tgctattctt attatgaatg catttacccc gctgatcaac
    13261 agttatatca aacctaaaca ttttggaggg aaataagcat ggcaaaacta aaatcaacat
    13321 tacccaatat gctcttgtcg cttaccatca tctgtttggt tgcgggagcg atattagccg
    13381 gagtaaatat gtacactacc ggcccgattg cagcctccaa agctgctgcg ctggaagctg
    13441 ctatcaaagc tgttacacct gaattcgaca acaaaccgtc agaggacgct tatatggcag
    13501 ttacaggcga cggcgattcc ctgaaaatct atccggcaac caaaggcgga gagttcgtag
    13561 gtgcagctgt cgaaagtaat acaaaaaaag gattcagcgg agagatcaaa gtgatcgtcg
    13621 gattcgataa ggaaggcaag ttattgaact attccgtatt acagcatgcg gaaactcccg
    13681 gtctgggagc taaaatgcag gaatggttca gtacggacaa gaataaacaa agcgttttgg
    13741 gacgcagcct gtccgccgga ccattaaaag taactaaaga cggtggcaac gtggatgcta
    13801 tcacagcagc aaccatcacc agccgtgcat ttctggatgc ggtgaaccgt gcttacagcg
    13861 cattcgccgg aactgacgga gtaaccggtg caacaaccgc taacactaac gagggaggaa
    13921 acgacaatga gtaatatgaa agtattgatg aacggtatca tcaaagagaa cccgacattt
    13981 gtcttgttgc tgggtatgtg tccaactctg ggaacaactt cttcagcatt gaacggtatg
    14041 agtatgggac tggcaaccat gttcgttctg atctgttcca atatggttat ttcagccttg
    14101 aagaacctga tccccgacat ggtacgtatt ccggccttta ttgtcgtaat cgcaacattc
    14161 gtaaccgtcg tgcagatgtg catggaagca ttcgttccgg ctctttacgc cagcctggga
    14221 ttgttcatcc cgctgatcgt tgtaaactgt atcgtgttgg gacgtgcgga agcatttgcc
    14281 gctaaaaacg gagtgatccc ttccgcattc gacggattag gtatgggact cggctttacg
    14341 ttggcactta ccttgctcgg agctacccgc gaactgctgg gaacaggtaa actgttcggc
    14401 ctgaccctga tgcccgaaca atatggttcg ctgatctttg tat
//
