LOCUS       c00043_gnlPro..        17076 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NGAPLHMB_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 06:00:21
            Original ID  :: gnl|Prokka|NGAPLHMB_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17076
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17076
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3497:7076](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3498..7076
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..17076
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17076
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(2..616)
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLIVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTE"
     CDS             complement(869..1654)
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="MAPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALAAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADCLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGLIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             complement(1672..3153)
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEGSASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWKRADYQDLIRGVAGEDWFDIS
                     PEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             3498..7076
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_4"
                     /sec_met_domain="PFOR_II (E-value: 4.7e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.5e-79, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.3e-32, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-12, bitscore:
                     36.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 8.5e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 9e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2.4e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATTGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLTRQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             complement(7542..7979)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             8103..8423
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPVLASMAEWGSKYQRE
                     NR"
     CDS             complement(8507..10645)
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPALVSAGTPGDAG
                     NLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGKPRTLSSLHVW
                     PYWEGGRIYKYKIEGSEDGKNWKMLADQSSNSIAATPEGVPFKFNPQTVRYVKITFLGN
                     SAGNEKGGHLVEIKGYGPDAALSLQVAAVKDYDRIPYNGAPGQEMLQDAVRLFGWRGER
                     AGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLISDIIGSENSCD
                     LQAGGVRPVWVEVNIPPSAKPGVYKGKVVVSAESGFPVSVLVILEVAPESLPAPAHWQV
                     HLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLIDEAWNAQTYDW
                     FPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNMKIRYLDEATG
                     KYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSRGWLGKTCIGLDERPDAMVRAAKNVLDK
                     YAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKTTFYVCVHPKK
                     PNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWPAGDCYLVYPG
                     NLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFTVEKSRGNSHE
                     EDVRKAREIIRKTTEISR"
     CDS             complement(10693..11460)
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="VLAKRIIPCLDVTDGRVVKGTNFINLRDAGDPVECARAYDAQQAD
                     ELVFLDITASSDGRATMADVVRRTAACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNT
                     AAINRPELINEGAAAFGSQCIVVAIDAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAER
                     RGAGEILLTSMDADGAKTGYDIELTRAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADA
                     VLAASIFHFGEYTVPEAKAYFASRGIPVRPLAE"
     CDS             11520..11720
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MPFDKHVPFLTKALFGSASIPHIHGKRNLLKFINITIPLTFRPAL
                     PRHEETQCGICPFPARMHKTA"
     CDS             11774..13522
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLM
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEGNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLSGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             13533..14237
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MRYTVIGLGQFGQELCTELSARNIEVVAVASTDEELEQIKDLVTY
                     AVVTDYTNPAALRELELDDQSAVIVAIGDSFEENLLVVTHLQKMGVRYIYARVMSPVHE
                     HILSQMNVYALINLSRVASKQLASQLESPEFLRVSPMDENHSIVEIAVPRIWVGKRLRD
                     VGLRTEHHLNLLTIRRGEAQTPQGRREILSIPRIPVIGTPSPDLVFEDHDILVLFGKET
                     NLIEFAQLSKGL"
ORIGIN
        1 gctccgttcc gttgagaagc cttgcgatat tggaacggtg cttgagaatc accagcgcgc
       61 ctaccaccgt gaaaaaggcg acgtaaagta tctgggggga gacatccccg tcctggcaaa
      121 gcggataaat ccaccatcca gcggcgatca tcaccacagc ggccaccagg ctggccaggg
      181 acacgatgcc ggagattccc ataaccacca gccaagaagc cagagccacg caagctacca
      241 ccggattgag ggcaaataaa acccccgcgg ttgtcgctac gccttttcct cccctgaatc
      301 ccaggaaaca ggtgtaagta tgaccgagta taacagcgaa acaggagaga actatcaaga
      361 cattgaaatc ccagccgccc gcatcccccg tcaggaacgg cagccagttc aaggcgccga
      421 acacagggat gaaccccttt aagaagtcca gaatgaaaac ggaaaggccc cacttccagc
      481 ccagtacgcg ccacgcattg gtagcgccta tgttgcggga accctgctgc ctcaggtcaa
      541 tccctctgat tctgccggca aggtagccga acggaatcgc tccgatcagg taatagaaaa
      601 ctatccaggc aatcatgttg tgcggagtgc attttaatcc tccgccggtc aaatgacaat
      661 ggggaaatca cctctggccc ggttctttcc ggaggggttg ctctcgtaaa agaacaccat
      721 gcctgacggc ctcctccaga tcctcatttt caaggctctc cgtgccccgg cctgcgaaaa
      781 agccctgttt aaggtgcaat aagaacagcg caaacatttt cccgcccgcc cagaaccatg
      841 ctcctgcact tccttcgccg gaataagctt atttaccgcc ctcgcagggt ttccgcatga
      901 cggcagccca gacggaggca ttatcctgct ggggctccag catatccttc acctgttcca
      961 taatgagccc caccagctcc ctgctggaac aatccctggc cttttgaaga gccaggaaag
     1021 aaggttctct caacagctcg ctccaaacct gcaagccatc cgagcatgcc agcaccgcat
     1081 ctcccggatg caggagcagg ggcatggcgc tgatgtccac cagttccatg ggaccgccca
     1141 taacggcgga acggagaatg caacgctgcc gaagcgcacc ctgaagtgac attttcccct
     1201 tccggtaaag gcaatccgca atcggtctca tggaatggtc ttcattcaga cggtccatgc
     1261 gaaagctgtc cgctccgctc cataaataca ggggggagtc tcccacgctg atccaccaca
     1321 ggaaatggtc gcggatgaag acggccagca atgtggttcc ggattcctcc ggttccttct
     1381 gaatggcggc caacgccctg ttggcagcat gcaaagccgc cgttaaacgt tccgggatat
     1441 cctcgatgcc gctttccgca aataccgcag caaattcctg cgccaccaca caggaggcgc
     1501 aatctccgcg aagatgccct cccatgccgt cgcacacgat gcccagcatc ccgccggcgg
     1561 cgggaagact tttaaccacg tcttcctgct cgcggcgttt gccgatccat tgggcggaag
     1621 cgcagtccag aatatccggg gtgcggggag ccatgcggcc ggtggttcgg attaactgtc
     1681 cttacgtttc aactgcggga agagcagcac gtcacggatg gaagaggctc ccgtcagcat
     1741 catgacgacg cggtcgatgc cgatgccgat gccgcctgcg gagggcattc cgtattccag
     1801 cgtttcaatg aaatcatagt ccacgcgctg ggtctccccg gcagcctggt gttccaggcg
     1861 ttccttttgc acgtcaggat cgttcaattc cgaatagccg ggggaaattt cctgcccgtt
     1921 gatcaccagt tcatatacgt ccactacgtc cggattttcc cggttcagct tggccagggg
     1981 aaccaggtcc ttggccacgt gggtaacaaa gcagggattc atggtctttt cctccaccag
     2041 tttttcatac acctgctggg aaacatccac atctttcata tccgggctga tttccactcc
     2101 cagctcttca cagcgggcgc ggcgcgcttc gggggaaatg tcaaaccagt cttcccccgc
     2161 cacgccccgg atcaggtcct ggtagtcggc gcgtttccag ggacggctga ggtcgattgt
     2221 gtaaagaacg ttgccttccg catccttgtg gtcaatctga aggccgccgc agaatttttc
     2281 cgccagatgg cagatgagct cctccaccat attcgccatg gtttcaaaat caccgcaggc
     2341 gcaataggct tccagcatgg tgaattccgg gttgtggcgg cggtcaatgc cttcattgcg
     2401 gaagctgcgg ttgagttcga aaattttcgt gaagccgccc accatcaggc gcttgaggaa
     2461 aagctccggg gcaatgcgca gcgtcagcgg catatccagc gcgttatggt acgtttcaaa
     2521 cggcttggcg gcggccccac cggccacatc ctgaagcatg ggggtttcca cttccagata
     2581 accgcgttcc tggagaaagc ggcggatttc cgcaatcatg agggagcgcg tcacgaacag
     2641 ggaggcgctt ccctcattgg aaatgaggtc caggtggcgc ttgcggtagg tcacctcctt
     2701 gtccgccagc ccgtgccact tgtccggcag ggggcggagg cttttggaaa gaatggtcag
     2761 cccggatacc tttacggtag gttctccggt acgggtcagg aacgtggttc ccctgatgcc
     2821 gacccagtcc ccgcggtcca ggagcttcca gagcttccag gtggtttcgt ccacctcatt
     2881 tttatgcagg aacccctgga tttttccccg tacgtcccca atgacaaaaa actgggattt
     2941 gcccatgtcg cgaatagcca gaaggcggcc ggcgacggct acctgtttgt cttcctggaa
     3001 atcggctttc aatccggcgg gagtggtggt cacgtcaaat cttgcgccgt aggggtcaat
     3061 tcccagctca cggattttgg cgagcttgtc gcggcgcacg gcaataagtt cggattccgt
     3121 cgtggtcgga tgtgcctgct gttgttcgga catagtgcgg ggattctaaa ggctcgcttc
     3181 cgttttggct agcgcattgt caggcagagg ggacattttt ggcggccggt tttgacccga
     3241 aggttcctcc cccccttttt cggaagccgg atgccggaac atgccccagt atttcagccg
     3301 ttttgcaaaa agcctgaaca gaaccacata aagcacgata ttcaaaggaa ttgaaacaaa
     3361 actggtctta ttattaaaaa atggccggca aatccccaca tacgcataat tgcttttacc
     3421 tttggcacca gacatgttat aaatgtttcc gttaagacgc accttattta tcaattatat
     3481 actatccgtg cagacttatg agtgatcaga caaccgtaac ttacagcacg attgacgcta
     3541 acgaagccgt agcctccgta gcctatcgtt tttctgaagt cattgccatt taccccatta
     3601 caccatcttc tccgatgggt gaatcagctg aaagctgggc cgctgtcaac aggaagaatc
     3661 tatggggcac cgttccctcc gtggtggaaa tgcagagtga aggcggcgcg gcaggcaccg
     3721 ttcacggcgc cctccagacc ggagcgcttg caactacgtt caccgcatcc caagggctcc
     3781 tgctgatgat cccgaacatg ttcaaaatcg caggggaact gactcccgcc gtgttccacg
     3841 tagccgcccg gtccctggct taccaggccc tttccatttt tggcgaccac agcgacgtga
     3901 tgagcgcccg ctcctgcgga tgggccatgc tgtgcggctc ctccactcag gaagcggcgg
     3961 acttcgccgc tatttcccac gccgctacac tggaatcccg cattcctttc atcaatttct
     4021 ttgacgggtt ccgcacgtcc cacgaaatcg gcaagattgc agacatcacg gacgacaccc
     4081 tgaacggcat gattaaacag gaatggctgg attccttccg ggaacgagcc ctgacccctg
     4141 atgctcccgt tctgcgcggc actgcccaaa acccggacgt ttatttccag gggcgtgaaa
     4201 cggtcaaccg tttctatgaa gccactccgg ctattgtcca gaacgccatg gacaagttcg
     4261 cggaacttac cggccgttcc taccatctgg tggattacac cggcgctccg gacgccgaac
     4321 gcgtcattat cctgatggga tccggcgctg aagctgtgga agaaacggta gaagccatga
     4381 tgacccggga aaacgccaag gtaggcgtgc tgaaggtgcg cctgttccgc cccttccccg
     4441 ccgccgaact cgtcaaggcc ctccccgcta cggtcaggaa aatcgccgtg ctggaccgca
     4501 ccaaggaacc cggctcccag ggagaaccgc tccaccagga catcatccag gccctcttcg
     4561 acgcccaggc caacggcacg ctgcccttca ccaacggcat gcccaaggtg gtaggcggac
     4621 gctacggcct ctcctccaag gaattcaccc ccgccatggt caagggcgtc tatgacaacc
     4681 tggctctgga cactcccaag aatcatttca ccatcggcat taacgacgac gtactgggca
     4741 ccagcctccc gtatgatgaa gattattcca cggaagcgga cgacgtgacg cgggccatgt
     4801 tcttcggcct cggctccgac ggcaccgtgg gcgccaataa ggatgccatc aagatcatcg
     4861 gccagcatac gaacctgtat gtgcagggct atttcgtgta tgactccaag aaatcggggt
     4921 cctccaccat ttcccacctg cgcttcggtc cccgtccgat caaatccaca tacctgatca
     4981 ccaaggcaaa cttcctggcc ctgcaccagc cttccctgct ggatttgttc gacttcctga
     5041 agaatgccgc caacggcgcc actttcctga tgaacagccc gcacccggcg gacaagctct
     5101 gggacacgct gcccgcccgc atgcagcagc agattctgga caagaacatc aagctctaca
     5161 cgattgacgc ttttgccgtg gcccgcaaaa cgggcatggg cggccgcatc aatatgatta
     5221 tgcagacctg cttcttcaag ctggccagcg tgattcccgc ggatgaagcc atcggctaca
     5281 tcaagaaggc cattgccaaa acctacgcca agaagggcca ggaagtggtg gacaaaaaca
     5341 tcgccgccgt ggacgccacg ctggaaaacc tgcaccaggt ggacacaacc ggaaaaactg
     5401 taaacggaca cgccattccg cccgccatgt ccccggacgc tccggactac gtacaaaacg
     5461 tccttggcaa gatgatgtgc ggtgaaggcg acagcatccc ggtcagccaa atgcccgtgg
     5521 acggcacatt cccgaacgga acgtcccagt acgaaaaacg caatctggcc ctggatctgc
     5581 cggaatggga tccgaccctc tgcatccagt gcggcaagtg taccgccgtc tgcccgcacg
     5641 cggttatccg cagcaaattc ttctctcctg atgctcttgc aaacgctccg gaagggtttg
     5701 aatgcctgga tgccaagcat ccggactgga agggagagaa attcgtcatc cagatttccc
     5761 cgaacgactg tacgggctgt acgctctgcg cggacgtctg cccggccaag agcaagacgg
     5821 acccgacgca caaggccctg accatggtcc cggccgggaa gattcacgac aaggaagaag
     5881 ccaattggaa tttcttcctg agccttccgg acgtggaccg caccaaggta agaacggaca
     5941 acatccgctc catgcaggtg ctgcgcccgc tgttcgaatt ctccggcgcc tgtgccggct
     6001 gcggtgaaac cccgtatgta aaaatgctct cccagctctt cggcaaccgc ctggtggtcg
     6061 ccaatgctac gggctgctcc tccatttacg gcggcaacct gcccaccacc ccgtggtccc
     6121 atgactctga agggcgcggc cccgcctggg ccaactccct gtttgaagac aacgccgaat
     6181 tcggtcttgg cttccgcgtc tctctggaca agcagatgga acacgccatt gagcttcttc
     6241 atgaagctgc cggtgccgtg ggccaggaac tggtggatcg gatactggct aatccgcaga
     6301 aggatgaagc agacatcgcc cagcagcgtg aaaacattga agaactcaag aagaaaatcg
     6361 ccggcaagcc ggaatacgcg cgcctcctga cccttgcgga taaacttgtc cgcaagagcg
     6421 tgtggattct gggcggcgac ggctgggcct acgacatcgg ctacggcggc ctggaccaca
     6481 ttctggccag cggccggaac gtgaaggtgc tggtcatgga tacggaagta tactccaaca
     6541 ccggcggcca gtgctccaaa tccaccccgc gcgccgcagt agccaaattc gccacgaccg
     6601 gcaagcccgg agtgaaaaag gatctgggcc tcatggccat gacttacggc aacgtgtacg
     6661 tggcctccgt cgctctcggc gccaaggacg aacacacgct gaaagccttt gtggaagcgg
     6721 aagcctatga cggcccggct ctcatcatcg cctactccca ctgcatctcc cacggcatca
     6781 atatggccaa gggcctgcag cagcagaagg catgggtgga ttccggccga gtcctgcttt
     6841 accgctataa tccggatctg acccgccagg gcaagaatcc gctgattgtg gaaggcaaag
     6901 gcccgaaagg cgatctgcgc gatgtgctgc tcagcgaaaa ccgcttcaag cttctggcga
     6961 agaccaataa ggaaggattc gaaaaactcc ttgaagaagc ccagaaggat gtctggcacc
     7021 gctggaacct gtaccaaagc attgccggca tgggtgccga caaacctgcg gaataaggta
     7081 caggccgctt aatttcaacg cccctgtccg gcttatccgg caggggcgtt ttttactgcc
     7141 ggatttcatg aaaaacaaac catgaatatt tcggggaggg gactgccttt ccgccccgcc
     7201 atacagccac gcaagcaggc ttcctgcgcc agtactttcc cttcctgaaa accggagaat
     7261 tcatccttcc cccgcagcac aaaaaagggg cacaccttgc tgcaaggccg ggttttaata
     7321 tatctcacct tatacgggtt aatttccgca tggaggtttt gaaggccttc aaggaaccgc
     7381 agcctttgct gccagccatg tccaaggtaa agacgtgcat ctcatgcggc caagggaata
     7441 ctgttttctc acaccttcct ccccatagga gcgcggcccg ctttcctgcg gaccgcgccg
     7501 gtggaaaaac cggaaaaagg ctttaaaaca gggatgctgc ttcaagattc ccgaaaatgg
     7561 tgcacaccgg aggaggaata taccattccg gatgccgtat ccgggaagtg caccacatca
     7621 ggagtcaggc gagtgcccac atccagatag accagcttct ccgtagcgga tccgttgcgg
     7681 ataacatgcg ccccctccgg gctggcgggg aatgcaatcg catccccctc ttttaaattc
     7741 ttttcaccct caggcgtacg cacaacggca tggcccctga tgatgtaaaa tacctcttca
     7801 ttcacttcat gataatggta gccataggcg taccgccccg gctccacttc cacgaaactg
     7861 gccgcacatt ttccggcatc cgcttcccga atgacgggct ttaccgcaaa ggaattgccc
     7921 tcccggctga taacctgagg ttccgtctcc ctgtaattgg caatgatgat cttgttcatg
     7981 gcattatctg ttctgcttgc cgtaacggca agtacctatt aaaataggcg gcaacattct
     8041 ttctgtaaag taggcagaaa atagtaacct gaattcctga aagaaaccat tgcgtaaact
     8101 aaatgactta ctacaattca tcatgccctg ttgaaactac tctccaactg atttcctccc
     8161 gctggaaagt gctcatcctc cgcgatctgc tcgaaggcac ccggcggttt ggagaactcc
     8221 gcaaatccat tggacctgtg acgcagaaag ttctgaccgc gaacctgcgt tctatggaaa
     8281 aggacggcct gcttacgcga aaggtgtatg cggaagtacc tccgcgcgtg gaatatactc
     8341 ttacggaact ggggcgcagt ctgcgtcccg tcctggcctc catggcggaa tggggatcga
     8401 aataccaaag agaaaaccgc tgatcctccc ctccctttcc ggagcttaac cgaacctccg
     8461 gaaagacatg gaaatacagc ggttttcctt tttcccgcaa gaaaggtcag cgggaaattt
     8521 ccgtcgtttt acggataatt tcacgggctt tccgcacgtc ttcctcatgg gaattcccgc
     8581 ggcttttttc cacggtaaag agcttggaaa gctcttcatc catgcgggct acggcagctt
     8641 tcgccttagg attttttgcg gcacgagcgc gcaggatatt gaccttttca aattcctcca
     8701 gtccgtcccg gagtttttca aaccgcagag aactgagatt gccgggataa acaaggtagc
     8761 agtctcccgc gggccagttc ccgaaatccg tcttttcaaa cggattgcgg ttccaggaat
     8821 tataagccca tctcaaaaag ccgtccaaat gattggcggc ggcaaagagg ggaagccatt
     8881 ccgcctccgc cagcggggaa atagtgaagg tgttgggctt tttgggatgg acacagacgt
     8941 agaacgtcgt cttttttccc tcctttttgc gctgcgccag cagatcgccc gtaaccgtgc
     9001 ctgcatggtc aattacagga gagacgtcat aaacgtcccg ggtcatggcc gtaggccgat
     9061 tgacggcgga aacgattttg aattccgggg catacttgtc cagcacattc ttggccgccc
     9121 tgaccatagc gtccggccgt tcatccagcc cgatgcaggt tttgcccagc cagcccctgc
     9181 tcttgacgtg tttgcgaaaa tccgtcagga aaggccccca gatagcttca taggagggat
     9241 cgttcggctt aagatccaga aatttgtact ttccggtcgc ctcatccaga taacggattt
     9301 tcatgttcca gggaatcatg gtatagcagg atatctgtcc cttgacgccc acctcgttca
     9361 tcatgaagga aacccacttg tcaaaattgg cgtaattcca gcgcatggtt ccgtttttgc
     9421 ccttgaccca ttcaatcatg ggcgggaacc agtcataagt ctgggcattc caggcttcat
     9481 caatcaggga gcatgtaatg gccttttgcc cggcatccgc cagccttttc atcaccggct
     9541 tcatcagcgc gaaatgctcc ggagaccacg gttccacatc atgccagcgg gccacggcct
     9601 gcggatgctg ccacaagtcc agatgaactt gccaatgcgc gggagcaggg agggattccg
     9661 gcgccacctc cagaattacc agcacactga cgggaaaacc gctttctgcg gaaactacca
     9721 cttttccttt gtacacgccg ggtttggcag acgggggaat attgacctcc acccataccg
     9781 gacgcacgcc tccggcttgc aaatcgcagc tgttttcgct gccgatgata tctgaaatca
     9841 gcctgttgcc ccccctggtg tagcgtatca tggcagtccg gacaggaata atctgtccgg
     9901 cagcgttttt taccccggcg caggaggccg ataactgggg ctgcgcctgg gaagaccaga
     9961 cggcaatctg cccgccggcg cgttcgcctc tccagccgaa cagacgcacg gcatcctgaa
    10021 gcatttcctg cccgggagcg ccgttgtaag gaatacggtc ataatccttc accgctgcaa
    10081 cctgcaggct cagggcggca tcgggtccgt accctttgat ttccaccaga tgccccccct
    10141 tctcattgcc ggcgctattg cccaaaaaag tgattttaac gtaacggacc gtctgcggat
    10201 tgaatttgaa gggaacgcct tccggagtgg cggcaatgct gttggaagac tgatccgcca
    10261 acattttcca gttctttccg tcttcggaac cttctatttt atatttgtaa atgcgccctc
    10321 cctcccaata gggccataca tgcagggagg aaagcgtccg aggctttccc atatctatct
    10381 ggagccagac gggaatgccc tcgcaacccc agtatttgcc ggcgttattc gtctgcccgt
    10441 ccacggccag ttccggacgg tcactgccgt aatgaccgga agcggttact ttggctccgg
    10501 caaataaatt acctgcatca cccggagttc ctgcggaaac aagggcgggt tcatacaggg
    10561 gatgcctctc cagggactgg gcttggacaa aagacgttaa ggcaatagcg gaacacagag
    10621 gaaaaaaaag acagcgcata cgcatattac gcaccggaat ttcattttct ctcaaaagaa
    10681 aagctgtttc cgctattccg ccaaaggacg cacgggtatt cctctggaag caaagtaagc
    10741 cttggcttcc ggcaccgtgt attccccaaa atggaaaatg gaagccgcca gcacggcatc
    10801 cgccttccct tccaccagca cgtccaccat gtgatccaaa ttacccgcac ccccgctggc
    10861 gattaccgga atgcgcaccg cactgcttac ggcgcgggtc aattcaatat cataacccgt
    10921 tttggctccg tccgcatcca tgctggtcaa caagatttcc ccggctccgc ggcgttccgc
    10981 ctccacagcc cattccacgg catccagccc cacgaatttc cggcctccat gggtggaaac
    11041 gccccacttg ccggaagcct ggcgcttggc gtcaatagcg acgacgatgc actggctgcc
    11101 aaaagccgcc gcaccttcat taatcagctc cggcctattg atggccgccg tattcaggga
    11161 aaccttgtcc gcacccgcca gaagcatttc gcgcatgtcc tttacggaac ggatgccgcc
    11221 gcctaccgtc agcggcatga agcagcatgc cgccgtgcgg cgcaccacgt ccgccatggt
    11281 ggcacggcca tcggaagaag cggtaatatc cagaaaaaca agttcatccg cctgctgggc
    11341 atcatacgcc ctggcacatt ctacaggatc cccggcatct ctcagattaa tgaaattggt
    11401 ccccttgacg accctgccgt ccgttacgtc cagacacgga atgattcttt tagccagcac
    11461 ggccctatca agccatcacc gccgccaaag gaaaagccta aaatacggct tgccgcggga
    11521 tgccttttga taaacatgtt ccctttttga ccaaggccct cttcggcagc gcttccatcc
    11581 cgcatatcca cggtaagaga aatttactga aattcatcaa tatcactatt ccactcactt
    11641 tccggccggc cctgccccgc catgaagaaa cgcagtgcgg catctgcccc tttcccgccc
    11701 gcatgcataa aacggcctaa gagcttttct ttccatgtcc aggtggtaga gtccgcataa
    11761 ggtatttcca ttcatgacca ctacacgctc gggattcacc aaacttgcag ccgtctgcat
    11821 tgccattctt ctgggggcgg tggtctggga gctaggctgg cccttgacgc gggcggaaca
    11881 tgagtggtcg cggctgattg cagccgttgc cacgctgggc cacctgacgg gcattctggg
    11941 ttcctatttc cggaaggaaa tcaaccgccc ttccctgagg ctcctgattt tccaaatcat
    12001 cagctgcctc atgatttttc tcctgattgc cagggaacaa caggaagcgg gatacatgag
    12061 gttcacggag ctttcccgcc tgatgattac ggccgggctg attgccatcc ccacgctgat
    12121 gtccctgacc aggatttttg aatggctggt gggcaagcaa aaaaaaggcc ggcctcttat
    12181 ggcccccgcc atgcagtttg tagcttctct gggagtagtc atcctggcag gcaccggatt
    12241 gcttctgctg cctaattcca catatccggg tattacactc agttttacgg atgccctgtt
    12301 caccagcacc agcgcagtat gcgtcaccgg tctgaacgcc gtggattttg cccatacttt
    12361 caccccgctg ggagaaatgt tcacgcttgc ccttatccag attggcggat tcggcatcat
    12421 gacgttcgcc tacttcgtag ccatggtggc aggccagggt ttttccctga gggaccgcgt
    12481 gctgctgacg gatctgcttg atgaaggcaa cctgggggcc gtcgtctcct ttattaccac
    12541 tattgtggtc agtacgctgt tcatcgaact gtgcggcgcc gtccttcttt atttctcctg
    12601 ggaagggaag gacatcaacc tgatggggga gcctttgtgg tggcattccc tgtttcactc
    12661 cgtttccgcc ttttgtaatg ctggtttttc aactttcccg atgaatttga tggagccggg
    12721 catccgcctg tgctacagcg ggcaggcggt catcatggcg ctgatcgtat gcggcggcct
    12781 gggattcggc atttataagg aaatcaattc acgcctggca aaccgctttt tttccaaaca
    12841 ccgccgcctg cacatgcagt ggacccctta tttcaaactg gtgatgatct ccacggggat
    12901 tttgctggcg ggaggcgccc tggccatctt tgccgtttcc tctccccatg ccgcggaacc
    12961 gttgggggaa cacctctgga tttgcctttt cgacagcgtc acggcacgca cggcgggatt
    13021 caatatcagc gactacggcc gctatctgcc cgcagccagc ctcattatgt gcggtctgat
    13081 gatggtggga ggcagccccg gcggcacggc aggcggcatg agaaccacta cctgcgccat
    13141 tgcaggtgcg gaaatcctgc gcatcctacg cggcagggat catgtggaat tcttccgccg
    13201 ccgcatcgac cagcgcaccg tggcgcgctg cgtaattacc gtggtggtct cctgcgcctg
    13261 gatcggctgc tttaccgtcc tgatttgcgc cttggagccc tccatgagct ctctggatat
    13321 cttctttgaa aactgcagcg cttttgctac ggtaggcgtg tcgcggggca ttactccaga
    13381 tttaagcggt ccttccaaat accttcttat cgtcaacatg ctctccggcc gcgtggggct
    13441 cttcgctttt ctcattgcgc tggccggcac ccctactccg aggcattacc gctatccatc
    13501 cgtcaaaatc ccgttaacct gaatatacca ttatgagata caccgttatc ggcctgggcc
    13561 agtttgggca ggaactctgc acagaacttt ccgcccgtaa tattgaagta gtagccgttg
    13621 cctccacgga tgaagaattg gagcaaatca aggatctggt gacttatgcc gtggtgacgg
    13681 attacactaa tccggccgct ttgcgtgagt tggaactgga cgaccagtcc gccgtcattg
    13741 tcgccatcgg agacagtttt gaagaaaacc ttctcgtcgt cacgcacctt cagaaaatgg
    13801 gcgtccgcta catctacgcc cgcgtcatga gtccggtgca cgaacacatt ttaagccaga
    13861 tgaacgtgta tgcgctcatc aacttgtccc gcgtggcttc caagcaactc gctagccagt
    13921 tggaatcccc ggaattcctg cgcgtctccc ccatggacga aaaccacagc atcgtggaaa
    13981 tagccgtgcc gcgcatctgg gtgggcaagc gcctgcggga tgtaggcctg cgcacggaac
    14041 accaccttaa cctgctcacc atccgccgcg gggaggccca gactccgcag gggcgccggg
    14101 aaatcctgtc cataccgcgc attcccgtca ttggcacccc ttccccggat ctcgtttttg
    14161 aagaccacga cattctggtc ctgttcggca aagaaaccaa tttgattgaa ttcgcccaat
    14221 tatccaaagg attgtaaacc atcctccgcg agcaggctga gggtatccct ctccatttca
    14281 gaaaaaggcg ccggataagc cgcctgtgca aacagcctcc gtcctggttt tactggcttg
    14341 acaatgcctc aaaagaagcc accagacgtt tttcggagac gcggcccttg acggagatgg
    14401 cgggagcgaa aacggccagg cggtattctt ccagcaaata accgtattgc atccagcgca
    14461 ggtctccggc atgttccttc aaaacctgat gccagggaaa atacacgcgt tcaaagagat
    14521 ccaagcgttc caattccctg gcaaggggtt gctggccgat gcgtctgata cgctccgcaa
    14581 ttccctgcat gtaccgtttc aggtccggca agcgttccgc tccatgcgcc cacaggaaac
    14641 gggggcgtaa caaccagtca agctggcgct gaaggtcagc cgtaatgcgc tccgtatggc
    14701 gcacaccctt ttgcagcgcc gtaaagtccc tgacggcatg ttccgtaccc gccaccagtt
    14761 cccatatatc cgccacgtta tgcgccgcgt caaaaaggtt ttggcgcaga ttcatttccg
    14821 cagcagcgaa ttgctccgcc gtgcgcggca aaggacggcc catggctatc tccgcggcaa
    14881 cgtccaccag gtcttccgca ttggtagacg gctcccgtcc gagcatatga agagagagct
    14941 ttccttccag cttcaacgga aattttctgc ggagatggtt aagctgatcc gtctggcgca
    15001 ggcgcatgaa acgcaggcac ccctcccggt gggattccgc agcatccagt tcatcctcaa
    15061 agacacggac gcccacggat gctccttcat ccaccagagc cacataaccc ggccttcccg
    15121 ccacatccac cgtgtattcc aaatctccgc agctccattc cttcatgccg gttacggaca
    15181 cgatatcctc cgctgtttcc tggaaccgac gggaaagttt tttacccagg cggttattca
    15241 gttccgcaac atccgtgccc atggcaagct cttccccttc atcatcgcac acccatattt
    15301 tcgtaaccag ctccgcagga agacggttca tgtcaaaaaa ggagggcgcg caaaattttc
    15361 ccgtttccac ttccacaaat tccgccagtt tccccgccag cggcccgtcc ggttccaggc
    15421 catgcctcag ttccgcaaag taagcggcct tttggctgat aggctggaga aagacgcgca
    15481 aatccttggg aagggaacgc agcaggcatt ccgcccgctg ggccagatgg ccgggaaccc
    15541 cccactccgg caaccattcg ggaatatccg gcaactggtc gatgtggacg cccagggtca
    15601 cgccgtcatc ctccgcgccg ggatcattct ggtaatacac ggcatattcc gctcctttac
    15661 aggtgatttc atccggaaaa ccatccagca ggtctttccc ccagaattcg tacatagctt
    15721 cctgtggcgg aacatgcaga gcttccgggt ttttcttctc cataccggcg gcccaccgca
    15781 aaaaagccct ggccgtacag cagtccgggg gaacaagcct gttaaagaat tcaaaaactc
    15841 cttcctcaca ccagacctgg tccggacggc gcaacttcag ctctatctgc cgaacctctt
    15901 cccggagtgt ttccagatgc ctgatacagg cgggtttcgt gcggaaacca ccgcccaaca
    15961 ggccttcgcg tatcattatt tcccgcgcat gggcgggatt gatacggcca tagtgcacac
    16021 gcctgttatc aataatgcgc aagccgccgc acacgacgcg ttccactgcg taaacagccc
    16081 cctgctccct gtcccaccgc gctccggaat agtgtgattc gcacagatgg ggcgctacca
    16141 gctccaccca ttccggttcc aaaatggagg cgcggcgcat ccacaggcgc gtggtgtcca
    16201 ccaactccac gcccattacc cattcactcc tttttttacg gcggaacagg ccggaaccgg
    16261 gaaaaatgcc gaaggaacgt cctccggcgc cgcgatattc ccggttgtct gcatcccaga
    16321 ggccgaactg gcgcggaacg cccgccagga tgctccggtg aatcatggca aaggaagcct
    16381 gccgctccgt ttcttcttcc aaaggggaaa ttctgcattt cagtgtttcc ctgaccagcc
    16441 gggaaaggtc ctcccataaa ttgaaccatt ccatcatgcg gttgaaattg aggaaatttt
    16501 tcccgcacca tttccgaagc tggtttttac gccagcgcct tccctcccgg aattgccatg
    16561 cagccttcca taatttgagc agagacagga agtcactatc ttcttccttc cactgcgcgt
    16621 gggcctggtc cgctttctga gcggcatccg cagggcgttc acggggatcc atgatgccca
    16681 ggccggctac aatcaccagc atttccggca gggcctgttc atgttgtgcc tccagcagca
    16741 tgcgggccag ccgcgggtca atgggcaacc gcgccagctt tctgcctacg ggcgtgagct
    16801 gccgggcttt gtccagagcg ccgatctccc gtaaggtgcg gtaaccttcc gtcaccagtt
    16861 tggatgaagg aggatccgga agcgggaact ccggcatttc cggcaatccc aggtctttca
    16921 tccggagcag cgccccggcc agtgcgctgc gcctgatttc cgggtccgta aagtccggcc
    16981 tgtcctccca gtccttctca ctgtacaggc ggatgcacac accttcgcac acacggccgc
    17041 aacggccggc gcgctggcgg gcgctggcct tggaga
//
