LOCUS       c00159_gnlPro..         4591 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHOGKPEP_159.
ACCESSION   c00159_gnlPro..
VERSION     c00159_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:40:10
            Original ID  :: gnl|Prokka|OHOGKPEP_159
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4591
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4591
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4589]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4589
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4591
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4591
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..721)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_1"
                     /sec_met_domain="IlvN (E-value: 6.9e-48, bitscore: 150.8,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.3e-13, bitscore: 38.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEA"
     CDS             complement(772..1524)
                     /locus_tag="ctg159_2"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(1521..2081)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_3"
                     /sec_met_domain="ALS_ss_C (E-value: 3e-20, bitscore: 60.8,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(2114..3865)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.2e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(3957..4589)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_5"
                     /sec_met_domain="ILVD_EDD (E-value: 8.2e-85, bitscore:
                     273.6, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNASYKELDTDRATGCIRDFEHAYSKDGGLAVLKGNIAQDGCVVK
                     TAGVDESIWKFTGPAKVFDSQDAACDGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPT
                     SYIKSRHLGKECALITDGRFSGGTSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRS
                     INVKLTDEELAARPMTPVTRNREVSKALKAYASMVSSADKGAVRLID"
ORIGIN
        1 atgcttcaga aggagtatgg ccgttttcac gcaatacttc atactgagcc aacagcaatc
       61 cctggatagc acccatcaat gaaccgcgtt caccggtcaa gtcggaagtg gcttcgcgga
      121 tgaaagttgt ctcgaacaaa tatcccgaac cgatgccgat acccagtgca atcgtcttgt
      181 caaaagcctt acccgtagca tcctgataga cggcatatga tgagttcaag ccacgaccct
      241 cgaggaacat ggtacgaagt gaagtaccgg aacctttggg agcaaccata ataacatcaa
      301 tatctttagg aggaaccacg ccggtacggt cgttccaggt aatagcaaaa ccatgagaga
      361 agtaaagagc ctttccggga gtcaaataag gtttgatagt cggccataca gacattacag
      421 ctgcgtcaga caacagacac atgatgatag tacctttctg acaagcctct tcgatgccga
      481 acaaagtctc acccggtacc catccgtcag ccacagcctt ttcgtatgtc ttacccggac
      541 gttgtcctac aatcacattg aaaccgttat cacgcaagtt gcaagcctgg cccgggcctt
      601 gtacgccata accgattact gcaattgttt catctttcaa aatctcacgt gctttttcca
      661 aaggaaattc ttcgcgggtc attacattct caataacacc gccaaaattc aattgtgcca
      721 ttttttgttt taatttttat ttgtggctta cgccaacgtt gataaattta tttatttctc
      781 tgtaaatatc actttagagc gacagaccac ttcgctgcca ttctttttca cctccacatc
      841 gtaaacgccc tcaccggcat catccatgaa caaagtcaac tcatccccat aatagctttc
      901 ggctacatat gccatttcaa aacgacggat gcgcttctcc ttatacatct ctatcgggaa
      961 caaatcaagg atatgctcga tgtaacggat gctgttcaca tgcccgttaa tgtcaatatc
     1021 actgtatttg gctaccaaag cagcaaccgg ttcctttgag gccaccttta tccgcgaagg
     1081 tttttctatc gggcaaggct catcgcaaac ataatctaca atgctgccac tatgaagagc
     1141 cagcaaatct gccggcttac gggtattcat gctaatcatc gcccaaacgg aacgtgcata
     1201 cccaatcttc ttaccctcct tatcgatgat agcgaaatta cggtctgtaa aaaggcgata
     1261 gacattctcc acccaagtct gaatggagaa atcttcgtac tgataaggca tttcatccag
     1321 ttcgacagcc agacgggaca atacccaagt ataattgtcc tcgtttagag tcgcgatgcc
     1381 aaaaccgcgg tcgctggcat ggaaacccgc acaattcaac aaatggttgc ccaatactcc
     1441 cattgtcagc cgtccggtaa agtcgacatg aaacggttcg gcaacaaact tgtaggtacc
     1501 tattttattg ttctcgctca tcatgattcc tggtgtttac tttgacgata ttttgcttca
     1561 cggtccgcca gatattcatt gacacgctca aagcagctgg tcgtaatggc tacgcgaccc
     1621 gaacggacga actgaagtac gcaatccaac tggcgcaact cctcataaag attggttatt
     1681 tcctcactca tgccattctt ctcaacaatg gcaaatacag cattcacctc cacaatacgg
     1741 gcattgtact tacggattac tttggacacc tccggttttt cttccagcgt aggggtcgtt
     1801 attttataaa gggcaatctc gtgctgatag atttcatcat ccgtgaaata atgggcttgc
     1861 agcacatcta ttttcttggt aatctgcttg gtcacctttt caatggtatc cttatccgtc
     1921 caagcggtaa tggtatattt atgtaccccc ttgatggagg aggccgatac attcaaactc
     1981 tcgatgttta tctgccggcg ggtaaacaca gccgtcacct gattcagcaa accggcaaag
     2041 ttttccgaat gaacaatgat tgtatatagt tttttatcca tagatagagt aaattcttta
     2101 atttcgcatg acttcagcat tccaacaaca tctgattgac cgaaccgccc ggaggtgtca
     2161 tcggcattac atttccttct tcctccacac aagcttcgag caggaacggt ccgtcagtcg
     2221 ctatcatctc gtcaatcgct tttgccagct cctcgcgggt cattaccctg cgtgcaggaa
     2281 tatcatatgc cgaagcaatc ttcatataat ccggattcat catcggagta aacgaataac
     2341 gacgattgaa gaacatcgcc tgccattgac gaacattgcc caagaagtta ttgttcaaca
     2401 gaatcatctt caccggagcc ttttgttcca tgatggtacc cagttcctgc aggttcatct
     2461 gcaagccgcc gtctcccatg aatacgcata ccgtgcggtc cggacgtcca aaagtggcac
     2521 cgatagctgc cggaaggccg aagcccatag tacccaggcc accggaagta acaatgctac
     2581 gttccttgct gtatttgaaa taacgggcgg acatcatctg attctggccg acatcagtca
     2641 ccaatatcgc ctcgttatgg gtagcctcac tcacagcacg caccacctca cccatgctta
     2701 gcgcttttcc tgccggatgt aattccggac ggattacctt ttcctcttcc acttcctcgt
     2761 attgccggaa actgtcaatc cattcctgat ggttggcggg ttccagcaat tgggtaacgg
     2821 cagccagtgt ctctttgcaa tctcccagga cagcaacatc agtctttaca ttcttatcta
     2881 tttcggcagg gtcaatatca aagtggataa tcttcgcctg cttggcatat gtttccaatt
     2941 tacccgtcac acggtcatca aagcgcatgc ctacggcgat aaggacatca catttattgg
     3001 tattgatatt gggccccagg ttaccgtgca taccaagcat tcctttgttc aacggatggt
     3061 tcgtaggtaa tgcggaaagt cccaataaag tgcatccggc aggcattccg gctttctcaa
     3121 tgaaagcacg aagctcttgc tgggcttctc ccagctccac gccttgtcca accagcacca
     3181 aaggccgttt cgcaccattt attaattcag cagccttccg tatggcctcc ggctccattt
     3241 cgggaacggg aagatagcta cggacatagt ccaccttagt aggcgcatat tctgttttct
     3301 ccacttgggc gtttttagca aaatccagca cgaccggtcc cggacgtccg ctctttgcca
     3361 catagaaagc acgtgccact gcccaggcca catcttctgc acgacgaatc tggtaactcc
     3421 atttcgtgat aggctgagta atgcctacca agtccacttc ctgaaatgca tccgtaccca
     3481 agaagttcgt ccctacctgg ccggcaatga caacgatagg cgtactgtca atcatggcat
     3541 ctgcaatgcc cgtgatagta ttggtagcac ccggtccact ggtaaccaga caaacgccaa
     3601 cctcgcctga tacacgtgca aagccttgtg ccgcatgggt tgctccttgt tcatgacgaa
     3661 ccaagatgtg gttcaattcc ttccgatggt cgtataaggc atcgaatacc ggcatgatgc
     3721 tccctcccgg ataaccgaaa atagtcttta ctccctgatg ctccagagag cgcatcaatg
     3781 cttctgcgcc tgttattaga gcctcacccc gaccctctcc ttgggagagg gaggaaaagt
     3841 tactcttttt attattatca gccatacttt atctattcat tatatttaaa agctcaatag
     3901 tagcttgaaa aatttgtttc attctctcct cccctcgctt tcggaaaggg gggcttttaa
     3961 tcaatcagcc tcacagcccc tttgtcagcg gaactcacca tactggcata tgctttcaat
     4021 gctttggaga cttcacggtt gcgggttacc ggagtcatag ggcgtgctgc aagctcttca
     4081 tccgtcaact tcacattgat agaacggttc ggtatatcaa tttcgataat gtccccatcc
     4141 ttaatcttgc cgatattacc accggcagcc gcttcgggag aaacatgtcc gatacttagt
     4201 ccggaagtac cgccactaaa acgcccgtcg gtaatcaatg cacactcctt acccagatgg
     4261 cgggatttga tataagaagt aggataaagc atctcttgca tacccggtcc acctttcggc
     4321 ccttcgtgag tgatgacgac gacgtctcca ctgaccacct ttccacccag aataccgtca
     4381 caagccgcat cttgtgagtc gaagactttc gctggccccg taaatttcca gatactctcg
     4441 tctacaccgg cagtcttgac aacgcaaccg tcctgagcta tatttccctt caaaaccgcc
     4501 agaccgccat ccttgctgta tgcatgttca aaatcacgga tacaaccagt cgcacggtcc
     4561 gtatcgagtt ccttataaga cgcatttaga t
//
