LOCUS       gnlProkkaFFPGMBEF_29   10635 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FFPGMBEF_29.
ACCESSION   gnlProkkaFFPGMBEF_29
VERSION     gnlProkkaFFPGMBEF_29
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 20:29:03
            Original ID  :: gnl|Prokka|FFPGMBEF_29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10635
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10635
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1321:5635]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1322..5635
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10635
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10635
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..95
                     /locus_tag="ctg29_1"
                     /transl_table=11
                     /translation="MGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             110..1258
                     /locus_tag="ctg29_2"
                     /transl_table=11
                     /translation="MSEQRQDKNLLSEPHKTESDEIEIDLVDIFRKIIAIRKKLYKAVG
                     IGFIIGIIVAVSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             1322..2041
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 2e-16, bitscore:
                     52.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLIAPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             2062..3363
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_4"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-12,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-120, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.2e-62, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             3380..4504
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 5.9e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             4514..5635
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg29_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_6"
                     /sec_met_domain="Aminotran_5 (E-value: 8.3e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        4604..5611
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg29_6_Aminotran_5.1"
                     /locus_tag="ctg29_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             5632..5775
                     /locus_tag="ctg29_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             6014..7462
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_8"
                     /sec_met_domain="Polysacc_synt (E-value: 8.3e-31, bitscore:
                     99.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWSAIERFSLQGVQFIIQIILARLLLPSDYGMIGMLAIFLQVAQV
                     FIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIADFYNMPTLVLVI
                     RFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWMAYVGCGVWALVW
                     QTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLINTVYRNLYTIVIG
                     KKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCLTNAYRNYIRLSS
                     YIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQINLNLLWVKGRS
                     DLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYYTNSLIDLTLKLQ
                     VKDVFPSLILSFIMGGIVFICISFFETDIVKIVIGCITGMSFYILLSFLFKLDSFFCIL
                     TLIIKTKNIDENIKKDFSSNSKDN"
     CDS             7416..7598
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKR"
     CDS             7753..8676
                     /locus_tag="ctg29_10"
                     /transl_table=11
                     /translation="MLYAFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDY
                     HMGDHSYDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNN
                     CNVIKREISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFN
                     AALILKLHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLV
                     NKPVIFNFYDIEEYRRVRGFSFEPIEFFCAGDIVYNYNELIDAVMGLLAGKDIHAEHRR
                     HISLLMNQFQDDNSTKRICDIFLNEI"
     CDS             8685..9431
                     /locus_tag="ctg29_11"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKKF"
     CDS             9435..10475
                     /locus_tag="ctg29_12"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
ORIGIN
        1 agaaagggaa catagctaat attttaggtt atgctacttc cttcagttct ttgggaatga
       61 tgattgcttc tattgctaat cttataaaga aataatagaa tttactttta tgtcagaaca
      121 acgacaggat aaaaacttgc tctctgaacc acacaagaca gaaagtgatg agatagaaat
      181 tgatttggtc gatatctttc gcaagattat tgctattcgt aaaaaattat acaaagccgt
      241 tggaattggt tttattattg gaataattgt agcggtaagt atccctaaac agtatacagt
      301 aaaggttacc ctttctcctg aaatgggtaa tgcgaagggg agtaatggtt tagccggact
      361 tgctgcctcg tttttaggag atggggctct aataggggaa agcacagatg ccttgaacgc
      421 ttctctttca gcagatattg tttcttcaac tcctttttta ttggaacttt tagaaatgga
      481 agtctccgtt tctaaaaagg atgataaaat gactttgggg tcttatctcg atgaagagtc
      541 atctccttgg tgggattatc ttataggttt tccgggcata gtaataggag gagttaaatc
      601 attattcgga gaagatacgg ttcctgccag tggagggcgg caaggaacta tcgaattgac
      661 gaaagaagta aatgagaaga ttaattttct taaaaagaag attagtgcat ccattgataa
      721 gaaaaccgcc ataacgagca ttacggtcac cttacaaaat ccgcagatca ctgcggttat
      781 agcagattct gtcgttcata aattacagga atatattatt gggtatcgaa cttcaaaagt
      841 aaaagaagac tgtgcgtatt tggaacggtt gtttaaagaa cgtcagcagg aatattatgc
      901 tgctcaaaga aaatatgcgg attatgtaga cgcccatgat aatgtggttc ttcaaagtgt
      961 acgtgctgag caggagcgtt tacagaacga catgagtttg gcttatcaga tatatagtca
     1021 ggttgctaat cagttgcagg tatccagagc caaagtacag gaggaaaagc cagtctttgc
     1081 agtagttgag cctgccgttg tacctttgaa accttcaggt atgggactca aaatttatat
     1141 tttattattt gtgttcctgt ccgtatctgg tactctcgtg tgggtgtttt ttggcaaaag
     1201 tctgctggct agcttgagaa aagaactgaa aaataaggag atagaacagg ataaatgatg
     1261 ctaaaacgtc gtttacaaca ttcttacatc aattaaattc acttactata ttattaaacg
     1321 aatgatacgt acagctatga taatggctgc gggcatggga acccgttttg gccaatatac
     1381 agaattgata cctaaagggt tcgtcaaagt gggaggtatt ccaatgatag ttcgttctat
     1441 tgatactttg ttatcatgtg gcattgagcg aattgtaatc ggtacaggat ataaacaaga
     1501 agtttatgaa gaattgaaga cagactatcc tatgcttgaa acctgtttta gtcctcgtta
     1561 tgctgaaaca aatagtatgt atactttata taatacgcgg gagattctgg gcaatgatga
     1621 ttttttattg ttagagtcag atttgatttt tgagaaacaa gcaataatga gcttattgga
     1681 gtgtcctgcg gcagatgcaa tgctaatagc tccagtgaca aagtttcaag atcagtatta
     1741 tgtggaacat gatgataatt ttcgcctttc ttcatgttct gtcaataaga ataaactaaa
     1801 cgctaaaggc gaattggtcg gcatccataa actatccggt tccttttaca aaataatgtg
     1861 tgctgattat gcgagtattg ttgatgaaca acccaatttg ggatatgagt atgaattact
     1921 acgaatatct tgttctcaat ctcctgttta tgtgcataaa gtagaagggc tgaaatggta
     1981 tgaaatcgat gacatatcag atttggaata tgcagagaaa tatattgttc cgtattgtta
     2041 attaaaataa tatatcaaat tatgagtaag acagtttata ttgggatgac tgcggatatt
     2101 atgcatccag gacttatccg cattattaat gaggctacta aatacggtga tgttataatt
     2161 ggtcttctta cagataaagc tattgcggag cataaacgcc ttccttatct gacctatgaa
     2221 caacgaaaag aggtagttca gaatattaaa ggcgtatgta aagttgttcc tcaagaagaa
     2281 tggagctatg ttgagaatct caaacgcatt aaacctgact atataattca tggtgacgac
     2341 tggaaaaccg ggcctttacg tgaagaacgt gtgcgcgtat ttgaagtgat gaatgaacag
     2401 ggaggaaagg ttatcgaaat tccatatact ttgggaatta attcatcttc tttggataaa
     2461 gatattaagg ctataggtac aacccctgat gtacgtttaa aatcacttcg tcgtttgata
     2521 aatgccaaac ccgtagttcg tattttggaa gctcatgatg gactatgtgg cttgataatt
     2581 gaaaatcagg aaatattaaa aggggataag agggaagtat ttgacggaat gtggtctagt
     2641 agccttacgg attcaaccag taaaggtaaa cctgatattg aggcggttga tttaactacc
     2701 cgattgcaag atttgaataa tattctggag tgtactacta aacctattat ttttgatgga
     2761 gatacaggtg gtaaaattga acatttcgta tttacagtac gcactttaga acgtcatgga
     2821 atttcagcta taataattga agataaagtt ggattaaaaa agaattcatt gtttggtaca
     2881 gatgttattc aaactcaaga tacaatcgaa ggtttctgta ataagatcaa agcaggaaag
     2941 gcatctcaga ttactgatga ttttatgatt atcgctcgta ttgagagcct tatagcggga
     3001 aagccggtaa gtgatgcttt agagagagct tttgcatatg tccaagcggg agcggacggt
     3061 attatgatac atagcaaaaa taagtcgggt gaagatataa aagaattttg tttggcgttt
     3121 cgaaaacagt atgctcatgt acctatcgtg gttgtgccta ctacatatga tcatatttat
     3181 gagtctgaat tgtgtgattg gggtgtgaat ataattattt atgctaatca tatgcttcgt
     3241 gccgcttatc ctgctatgat gaatgtcgca aagataatat tagagaatga acgtgcttta
     3301 gaggtgcgcg aactgtgtat gcccataaaa gaaatattgg aactgattcc aggtactaaa
     3361 taaaaagagg aatatcatta tgttaagcgt agaaaaagtt tatgaaacgt ttctgagtca
     3421 tgacgttgat ttttttacag gagttccaga ctcattacta aaaaatattt gtgcctatat
     3481 cacagaccat acttcacgtg agaaacatat catagctgct aatgaaggtg cggctgtagg
     3541 aattgcttca ggttattata tggcatcagg taaggttcct gtggtttata tgcaaaattc
     3601 cggcttgggt aatactgtta atcctctgct gtctcttgca gatgaacaag tatacagttt
     3661 tccaatgctt ttgatgattg gctggcgtgg tgaaccggga acaaaagatg aacctcagca
     3721 taaaaaacag ggtgaggtaa ctttagattt gttgaaagca atgcggattc cttatataat
     3781 tcttgattca aatgagaatg atgcatttat tcagctccat gatatcatac aatcagcaaa
     3841 aactaagaat attcctcatg caataattat tcggaaagat gtttttggca aatataaact
     3901 tcaaaaagag ttcggatgta attatccttt atctcgtgag gatgctttgc aaatagttgt
     3961 ggattatctg cctgaaaatt cagtggtcgt ttctactact ggcaagcttt ctcgtgagtt
     4021 atttgaatat cgagaaatga aagagcaagg tcatgaacat gattttctca cggtaggctc
     4081 tatgggacat agttcatcaa tctctttggg tattgctata gcaaagcaag atagacctgt
     4141 ttattgcttg gatggtgatg gagcatttat tatgcattta ggggcaatta gtaacattgg
     4201 cgatttatct cctaaaaact attatcatat tttgtttaac aatggtgctc acgagtctgt
     4261 aggaggacag cctactttag gatttagttt agatattccg gctattgtcc gggggagcgg
     4321 atataagcat acttatactg tttgtacaaa agttgaaatt gaagaagcaa tgaagcagct
     4381 tccaaagtta tgtggtcctg ttttgttgga aataaaggtt aaaatagatt ctcgggagaa
     4441 tttgggacgt cccacgacta ctcctataga gaataaggag cattttatgg attttttaaa
     4501 ataaatatat tcgatgaaaa tagaaagaaa aatattatta aatcctgggc ctgccactac
     4561 tactgacagt gtaaaaatgg cacaagttgt tccggatatt tgtcctcgcg agaaagaatt
     4621 cgcaggtatg atgaaacaac ttcgggacga tttggtcaga gttgctcatg ggaatttgga
     4681 aaaacatacc gctgtattat tttgtggctc aggaaccatc aatattgata tatgtctaaa
     4741 ttctcttctt cctgaagaca aaagggtgct tatagtgaat aatggggcat atagtacccg
     4801 tgctgtagaa gtgtgtcaat attatggttt gcctcatatt aatttggaat tttccgttta
     4861 cgaacgtcct gatttatcgg tggtggaaaa tgtgttgcaa gaaaatcctg atatagctat
     4921 ggtttatact actcatcacg agacgggtac aggaattctg aaccctattc gcgagatggg
     4981 cgctatagct cataaatatc aggctaaatt tgtcgtcgat actacttctt ctttgggcat
     5041 gattcctttt gatatagaga aagataatgt ggatttttgt atggcatctg ctcaaaaagg
     5101 acttcaagcg atgacaggtc tttcttttat tataggcaat gaggaacaga ttaagttttc
     5161 aaaaaaatat cccaagcgtt cttactattg taatctttat ttgcagtatg agaattttga
     5221 gagaacaggt gaaatgcatt ttactccacc ggtacaaact atttacgcca ctcgtcaggc
     5281 attaaatgaa tattttgaag tgggtgaaga agctaagttt gcccgtcaca aaagagtttt
     5341 tgaggctatt cattcaggta taaatgaaat tggtcttaaa agtgtaataa agcgtgaatg
     5401 gcagtcagga ctggttgtct cagttcaata cccagaagat cccaactggg attttgagaa
     5461 aatacatgat tattgttatg agcgtggatt tacgatttat ccaggtaaga tatcaactga
     5521 ggatactttt agaatctgtg ctttaggaga gatagaagta gatgatattg agaacttctt
     5581 taaagtacta aaagctgcat taaatcatta taacgtcaca ttaccgatgt catgattgca
     5641 gaaatattat tgaagattcg tcatttttat ttttcccttc gtggtataca cttccatccg
     5701 gaaagtgtta tttctggagt gcctattcgt agctttcgct tagtaggcaa atatggcaat
     5761 attaatttga ggtgatgcat taggagttct ttattcttat aaaaaggcat cggtagttat
     5821 aggagataat gtttgtgtag ggtaatttgc ttttagtggg agagaccata ttagaattgc
     5881 ggtaaggggc gaagaagata ataaccaatt agtgagaata ttggaaaaat ataattgata
     5941 tcggtaaatg tagttgtttt tatactgtat ttaagtaatg gaaaatctaa agcagaaaac
     6001 tgtatcagga ataatgtgga gcgctataga acgtttctct ttacaaggag tacagtttat
     6061 aattcaaata atattagctc gtttgttact accatcggat tatggtatga tcgggatgtt
     6121 agctattttt cttcaagtcg ctcaagtatt tatagatagc ggttttacaa atgctttaat
     6181 ccagaaaaaa gatagaactg aagaggattt tgccactgtc ttttatttta atattcttgt
     6241 cgcagtatta ttctatggta tattgttttt ttcggcttct ttgattgcag acttttataa
     6301 tatgccgact ttagttcttg taattcgttt tatagcattg tcgttgataa taaatgcttt
     6361 atcggctatt cacagaacga aattaattat ttctgtaaac tttaaaactc aatctaaaat
     6421 ttcattaggt gcagctttta tatcaggcgt gattggaata tggatggctt atgtcggttg
     6481 cggggtttgg gctttagttt ggcaaactct cttaaatagt ataattttga caattttgtt
     6541 ttactgttta gttcattgga aacctttaca tactttctcc aaaagttctt ttgaaagatt
     6601 attcaatttc ggatctaaat tattgatctc aagtcttatc aatacagtat atcgtaatct
     6661 gtataccatt gtaataggaa aaaagttttc tgttgtagag cttggttact atacaagagc
     6721 agaacaattt gctatttttc cttccaataa tttaaatgct ttagtttcta gagtagcgta
     6781 tcctatttta agttccattc aagatgatga taaatgttta acaaacgcat atcgaaatta
     6841 tatcagatta tcctcatata taatttttcc tttaatggta ggtttacttg ttttggctaa
     6901 tcctattatt agtctattgt taacagataa atggtctggg gttgttattc ttttacagat
     6961 attatgtttg gattggatgt ttgatcattt gagccaaatt aatttgaatt tattatgggt
     7021 taaaggaaga tctgatctgt cgttacgtct tgaaataata aaaaagacga ttgctatatt
     7081 cattcttttt gtgtcaattc catttgggct tgaggtgatg tgttggggta gagttattta
     7141 ctctctgata gcgacatatt tgaatacata ttatactaat tctcttattg atttgacctt
     7201 aaagttgcaa gttaaagatg tatttccaag tttaatactc tctttcataa tgggggggat
     7261 cgtttttata tgtatttctt tctttgaaac tgatatagta aaaattgtga ttggatgtat
     7321 tactgggatg tccttctata ttttactttc ttttcttttt aagctagatt cttttttttg
     7381 tattttaaca ttgatcatta aaactaaaaa catagatgaa aatattaaaa aagatttttc
     7441 aagtaatagt aaagataatt aaccattgtg tgccagttga tagtagatca ttgtatttta
     7501 ttcctcatcc taattgtaga acagataaat atgatattat aaattattcg tcagataatg
     7561 ttctcgttct gttaaattat ttgctaaaaa aaagatagtg ctgaatatta taaaatatat
     7621 gttgaaattt atgattcttc tcgtatttca gaatatcaag aatatattta tggcataaat
     7681 cctaatatta ggtgtacttt tttatgtgca tgtgttggac gttttttctt taataaagta
     7741 tcttttaagg atatgttgta tgcctttttt tgtttttgta gagcaagtaa atgttttaca
     7801 gctacttttt attatgattt ttcatttaaa aaacgctctc aacagattat ttgtttgggg
     7861 tattatactc cattcaaaga tgattatcat atgggagatc attcttatga taaatttcgt
     7921 aatacaacat gtaactcatt tgattactct attgctactt cttgtttaag tgctagaata
     7981 atttcaatag attgtggaat ctcatatgat aaattcaaag tcttaggatt tcccagaaat
     8041 gatttgttga tatcgaaaaa taattgcaat gttattaaaa gagaaatttc gaaatttgcg
     8101 ggatatgatg taactaaata tatagtttat actccaactt ttcgtgatta tgagactgtt
     8161 actgaaggta atttgcgttc aatactcgga tatgttgatt gtgatttgtt gaagttatcg
     8221 aaaatactat tgaagtttaa tgcggcttta attcttaaat tacatccttt gcagaataaa
     8281 acagtcttaa aaaaagattt acccaaaggt atacttgttt ttgaacaaac atataaatat
     8341 ggattgtatg atcttttgtc attttcagat ggaatgatta ctgattatac ttctacctat
     8401 tttgattttt tattggtaaa taagccagtc atatttaatt tctacgatat tgaagaatat
     8461 cgtagagtaa gaggtttctc atttgagcca atagaatttt tttgtgcagg tgatattgtt
     8521 tacaattata atgaattgat agatgctgtg atgggacttc tggctgggaa agatattcat
     8581 gctgaacatc gacgtcatat ttctttattg atgaatcaat ttcaagatga taattcaaca
     8641 aagagaatat gtgacatatt tttaaatgaa atataataaa taaaatgaat tatgcatttg
     8701 tggtgcaggc acgtttaggt tctacacgtt tgcctggaaa aatattgaaa cctttctatg
     8761 gtaatcaatc gattcttgac ttaatggttc ataagctttc tgctatatcg aatattccag
     8821 taattattgc tacaacaaat tctgttatca atgaacctat tgaaaagaag gcacttgcat
     8881 taggggtaaa gtgcttcaga ggtgaggaga atgatgtttt aaaacgattc attgatgttg
     8941 ctgaatattt tgatatacag ggtatattcc gaatatgttc tgataatcca tttttagatg
     9001 tacatgcggc aaggcaattg gtcgaaatag caatgaaatc ttgtaacgat tatataagtt
     9061 ttgatattga tggtactcca tcaattaaaa ctcatttcgg tttttgggga gaatttgtaa
     9121 cgcttgatgc gctgaagcga gttataggat ttactgatga tttattgtat cgtgaacatg
     9181 ttactaatta tatatatagt catcctgaac tttttaatat tcaatggatt tcaggatctc
     9241 cagtcgtgtc aaaacatcat aatattcgac tcacgattga tacgttagaa gatttttctg
     9301 tagcacagag aatatatagg gatttacaag aaaaaagagt ggaaatatcg atagaagtga
     9361 ttgtagacta tgttcgaaga catgcagaat acattcaact gatgaaacaa caaataaaaa
     9421 aaaaattcta aataatgaag aatacttata ttattggtga aatagggcag aatcataatg
     9481 gttctgttga cttggctaag ttgattattg aattaatctc acgacctgta catgaggatg
     9541 tttttggtat ggatttcatg ccaatgaatg ctgttaaaat gactaaaaga gatttatcag
     9601 aagaattggc tgtttctcaa atgaatcaaa tatatgacaa tcctaattct tttgggcgta
     9661 cttatggtga acatcgtgct tttcttgagc ttgatgatca agcgcatttt gagatttata
     9721 aatatgctaa gtcattagga ttagatttta tcgagacgtt atgtgccaaa ggatgtctgt
     9781 ctttgcttaa actgttcaca ccggataggc taaaagttgc tagtcgtgat ttgactaact
     9841 taccattgct tgaagcatta gcagaaactc atattcctat tatattatcg acaggaatgg
     9901 ctggtcaaag agaacttgac aatgcattag atgtgataac gagatatcat agtaatatag
     9961 ctattctaca ttgtgtatct cagtatccaa ctcatccaaa taatttgaat ctacgtacaa
    10021 taacatattt gaagaagcat tacaataagt ttgagatagg tttttctgat catacaatag
    10081 gtatttctgc tgctacagct gctgtagcga tgggagcgga aattatagaa aagcatgtaa
    10141 caattgatcg gcatatgaaa ggaacagacc agcttggctc tttaggtcca gatggggtta
    10201 atcgtatgat tcgagatatt cgcatagcag agtgttggct tggtactgaa gatctttata
    10261 tagaaaaagg ggtggagaag tctaagataa aacttgaacg ttctattgcc actcgaaaat
    10321 atattccagc aggtagtatt attcaagagt cggacattca tttactgagt cctggtgatg
    10381 gttataaatg gatagataaa aaaaatgtaa ttggtcattt tgctaaacaa gatatatcag
    10441 cgaatgaaat aatatatcct gattttattg aatagatata ttcctactgc aacttgtatt
    10501 acggtataga gtactgcctg ctataagcta agtagtgatt aataaataag ggtaaaatac
    10561 taaaaaaatg aaagagataa agcttatact tacagatatt gatggcgttt ggactgatgg
    10621 cggaatgttt tatga
//
