LOCUS       c00046_gnlPro..        13669 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJBDLMPH_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:43:12
            Original ID  :: gnl|Prokka|AJBDLMPH_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13669
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13669
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[342:3669]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      343..3669
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13669
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13669
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             343..900
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_1"
                     /sec_met_domain="SucD_FumR (E-value: 4.2e-99, bitscore:
                     321.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MICEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRAARGSER
                     YAVNVKPKTVEWASQNMLVLGIIVIAGLALHFANFWYKMQFAEIIGVHDLGAFGPTDGA
                     AYIRETFGCPVFTVLYLIWLAALWFHLTHGFWSALQTLGWSNKIWFERWKTIGNIYSTL
                     VVLGFAAVVVIYFVKSLACGAC"
     CDS             929..2893
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 193.8; E-value:
                     1.8e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.2e-60, bitscore:
                     193.8, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.7e-38,
                     bitscore: 120.2, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMATIDSKIPEGALAEKWTNYKAHQKLVNPANKRRLDIIVVGTG
                     LAGASAAASLGALGFKVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTI
                     KGGDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARG
                     QTGQQLLLGAYSALSREVQRGNVKLYTRYEMLDVVLIKDNEGVERARGIIARNLVTGKI
                     ERFAAHAVVIGTGGYGNTYFLSTNAMASNGSAAMQVYRKGAYFANPCFAQIHPTCIPVH
                     GDKQSKLTLMSESLRNDGRIWVPKKLEDAKALQAGTKKPTDIPDADRDFYLERRYPAFG
                     NLVPRDVASRAAKERCDAGFGVNNTGLAVFLDFKYAIDRLGEDVVRARYGNLFDMYEEI
                     TDENPYKTPMMIFPAIHYTMGGIWVDYELMTSIKGLYAIGEANFSDHGANRLGASALMQ
                     GLADGYFVLPYTIQNYLSDQIQVPRFSTDLPEFVAAEKAVNDKIQRLMNIKGHRSVDSI
                     HKELGHIMWDFVGMGRTKESLTTALAKLKEVRKTFWSDLRIPGEANELNVELEKAIRLA
                     DFIEIGELMAYDALNREESCGGHFREEHQTPEGEALRHDDKFSYVACWKYTGEGKEPEL
                     IKEDLNYQFVKVQTRNYKS"
     CDS             2914..3669
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_3"
                     /sec_met_domain="Fer4_7 (E-value: 8.1e-12, bitscore: 36.7,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-26, bitscore: 83.7,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-06, bitscore: 19.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKDKGHFDTFQMKDIPGDTSFLEMMDILN
                     EQLINEGKEPIVFDHDCREGICGMCSMYINGHPHGPATGATTCQIYMRRFKDGDTITVE
                     PWRSAGFPVIRDLMVDRSAYDKIMQAGGYVSINTGGIPDANAIPIAKPIADEAMDAAAC
                     IGCGACVAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKLVSISNIARLNREFIAAKLKD"
     CDS             complement(3666..4580)
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MSGLPCNERMDCTQCPKAVENSIHYTHNKKGFHLPPHKCETNILF
                     FLLKGQILINSEEYAGTIINPGEFVLQAIASKVEILAMTDSEGILYTFDDPKAFCYDRY
                     TYILKNVPPPLISEPLKIKPEIKLFLEGVTSYLNIDKICKELLEFKRKELYYLLAHYYT
                     DYELSPIVHSLSKYTNSFEYFILKHHKQIKSVEDFAQLGGYSVTTFRRIFKAIFNEPAY
                     EWMMKQRKESILYQLRYTEASISEICFEHGFESLSHFSNFCKKFFGDSPRNIRKREKEE
                     APGKKNAPPKAGHSQISSKTNRD"
     CDS             complement(4891..5190)
                     /locus_tag="ctg46_5"
                     /transl_table=11
                     /translation="MQFANDTGEIEIQYQVAVPVTCKILPYVEVSKQGVEFILGSYIIV
                     MLQHIQRQTFAETTRTDKEKITVGAFYQRDIHGLVHIIITIKAYIREIHHAVGQ"
     CDS             5206..5577
                     /locus_tag="ctg46_6"
                     /transl_table=11
                     /translation="LDAHCQTCFDYFCDIYAEYLPQGIKEQLDAKNGAVEQLDYLYHEC
                     ERVGQDIYLFIDEYDHFTNAILSDAESLHRYTKETHKEGYLRAFFNKIKSGTYSSIKRC
                     FITGVSPVTMDVVVSRGIL"
     CDS             complement(5741..5986)
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="MLYPQSLTDAKITVKYKTEKDNATFFNGSKEVALTGEWTNGQSIR
                     YILTLPVGAEKMSVNTTYDEDWNATDNEQTPKTPVL"
     CDS             6561..6746
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="VKLLLLVTVALELFLTIVFTPISFLLLGVPLSIPSISFCEQLVIA
                     NAAKAANKIFFISYVF"
     CDS             complement(6779..7750)
                     /locus_tag="ctg46_9"
                     /transl_table=11
                     /translation="MKKTRYAILVLLSSLLTLVGCSRREILDDYPVTGINIRLNWEGVT
                     DRLPEGVRIIFYPKDGQGRKIDTYLPAKGGEIKVPPGHYSAVIYNYDTEVVQIKDEGSY
                     ETIMACTGNCTGLGAEETKDMVWGPDNFYVATLDDVEIGKEEELPTLEVKPKSVVTTYT
                     FSIKTEGLKNVASILGSVSGMAECYHLGKGASLCRFAPIYCETSKGNGAIKGSFTCFGH
                     PKLTQARADITQFLNLIIVKVDGSKQEAKVEITEAVKPPEDKDEPGEGDEKPQEPEIEI
                     ELPDDEKIVVDDVEIPPDESGGGFDGNVSDWDDETNVELPVG"
     CDS             complement(7747..9003)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MTLYFDLNARQIDKDYQGNGKTLTVLDSLLANPAHSIHLNSIILV
                     SPDLYNGKKEQGIPLGQKRSEEVKVFLCGKYPQVNTAQICIRKGEEYGDALRKLILDDR
                     LVPDREDVLALIDYHHDNPVKMQDFLQRLDAGIPYQYISDRVLPELRRTEIRVCLSYPE
                     ENGGKNSSAEQAARIEETEFIPIDRETTVTPMTMQVLPQKERTQVIIETEKTVIKAEKK
                     KETKEKRGEKPKEKAARRVQTVDNTVLALKNNLLYDLALAPNIEIEIPVGKRWSVNMEY
                     KSPWWSNSSKEICYQLISGGIESRYWLGNRELHNRLNGHFFGLYIEGGIYDFQFKGNGY
                     QGKYYGAAGFTYGYSTLLSRHLALEFSLGIGYLTTEYQKYTPYEGSLVWMSSGNYTFIG
                     PTKAKISLVWLITKKRGRK"
     CDS             9464..9802
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MNQIFGGIECKLYICHVIFFIVLDLRLTKVGARRCSFLFLVPSVS
                     FHSPNHQLLNAVDFLKYSVSCFHPMDFMLSLCQCKLTNNLHEKTHKPFMLGGCCRIAEC
                     LRPGGERS"
     CDS             9786..11603
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="VVNAPEPVLPVPEKKQVDWQKMETYAFVHFGLNTFNDREWGYGDS
                     DPATFNPVKLDCEQWVKTFVAAGMKGVILTAKHHDGFCLWPTGLTEYCIRNTPYKDGKG
                     DIVRDLSEACKKYGIKFAVYLSPWDRHQANYGTPEYVDYFYQQLHELLTHYGPVFEIWF
                     DGANGGDGWYGGAKDSRTIDRKNYYDYARAYEMIDKYQPQAVVFSDGGPGCRWVGNENG
                     FAGATNWSFLRAGEVYPGYPKYRELQYGHADGNQWTAAECDVSIRPGWFYHPEEDDRVK
                     TVEQLTDLYYRSVGHNATLLLNFPVNRDGLIHPVDSANAVDFYKNVQKQLANNLLKGVL
                     PIVSNERGGKYTAKAVTDGEYDTYWATEDSVTSAVIEFEWPAPQKVNRMLLQEYIPLGQ
                     RVQSFVVEYNKEGEWLPVKLNEETTTIGYKRLLRFETVTTDKLRINFMESRACLCINNI
                     EAYYAGETPDVFTAKAEELKTYPFTLPQVDEAEAGKCADKDAATTCFVDGNTLLIDLGT
                     EQTVSSFHYLPDQSEYNKGLIAAYEISVGMEANAVNQVVSSGEFSNIKNNPILQSVYFT
                     PVTARYVLLKAVRMVENESPMGFAELGVQ"
     CDS             complement(11684..12799)
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MTQDEQICSLALTRIPGLGLTGAFRLVSSLGSATRVFEHRKELSQ
                     LVPGVSEKIITALNNSEAFRRAEQELTFCQKNHIRCLTLNDEGYPSRLRECDDAPLALF
                     YRGNADLNTLHIINIVGTRHATPYGQDICTRFLADLSVLCPNTLIVSGLAYGIDIHAHR
                     AALQNHFKTIGVLAHGLDRIYPAEHRKTAVSMLEQGGLLTEFTSGTNPDRQNFVKRNRI
                     VAGMSDATVVIESAAKGGALITAELAESYHRDCFAFPGRCNDEYSIGCNNLIRKNQAVL
                     ITSAEDLVKGMGWESSPKTEKTVQRELFPDLSEEEERIVKRLGKIPEGLQINTLVIDTN
                     IPVNRMSALLFELEMKGVIRALAGGVYRLIM"
     CDS             complement(12796..13239)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_14"
                     /sec_met_domain="HBT (E-value: 3.6e-11, bitscore: 34.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 1.1e-09, bitscore: 30.0,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQSNTFFLYLCFMEKYIYELKMKVRDYECDLQGIVNNANYQHYLE
                     HTRHEFLTSVGISFARLHEEGVDPVVARLTMAFKTPLRSGDEFVSKLYLKKEGIKYVFY
                     QDIFRLPDMKVTVKATVESVCVVNGRLGDSALFDETFAPYLSE"
ORIGIN
        1 aatcgcaaaa aaactgtcgt gtcatgagag gataaaagag ttgcggaaat gagggaaaaa
       61 taatgtaatt cgcatttacc cttcccgaat taaagaataa tttccataat tccttgtatt
      121 atcgctagaa ttcctttact tttgcatcgt gaatacacag cttttaacag aatttttagt
      181 tctaacaatt aaataattta aattcaatca tttatgtggt taagtaattc atctattgga
      241 aggaaagtgg tgatgagtgt cacaggtatc gcccttgtcc tgtttctgac gtttcacatg
      301 gcgatgaacc ttgttgcgct cttctcggaa gatgcttaca acatgatttg tgaattcttg
      361 ggagctaact ggtacgcgtt ggttgcaact gccggactgg ctgctctgtt cgtaatccac
      421 atcatctacg ctttctggtt gaccatgcag aaccgtgcag ctcgtggtag cgaacgctat
      481 gcagtgaacg ttaaacctaa aactgtggaa tgggcatctc agaacatgct tgtcctgggt
      541 attatcgtca ttgccggatt ggctcttcac tttgccaatt tctggtacaa aatgcagttt
      601 gccgaaatca tcggtgttca tgatttaggt gcgttcggcc ctacagacgg tgccgcttac
      661 atccgtgaaa cattcggatg ccctgtattt acagtgcttt acctcatttg gttagcagct
      721 ttatggttcc acctgactca cggattctgg agtgctttgc agacattggg ctggagcaac
      781 aaaatctggt tcgagcgttg gaagactatt ggtaacatct actctacttt ggtagttctt
      841 ggttttgcag cagtagtcgt tatctacttc gtaaaatcac tcgcttgtgg tgcttgctaa
      901 tcgtaaattg taaatgataa aattgtaaat gaatatggct actatagatt ctaaaattcc
      961 tgaaggcgct ttagccgaga aatggaccaa ttataaagct catcaaaaat tggtaaaccc
     1021 tgccaacaaa cgtcgtcttg acattattgt ggtaggtacc ggtttggcag gtgcttcggc
     1081 tgctgcttca ctgggtgctc tgggtttcaa ggtattaaac ttctgtatcc aggactctcc
     1141 ccgtcgtgca cactccatcg ctgcacaggg aggtatcaat gctgctaaga attatcaaaa
     1201 tgatggtgac tccgtttacc gtcttttcta cgatacaatt aaaggtggtg actatcgtgc
     1261 acgcgaagct aacgtttacc gtctggccga agtgtcaaat gctattatcg accagtgcgt
     1321 agctcaaggt gttcctttcg ctcgcgaata cggtggtttg cttgacaacc gttcattcgg
     1381 tggtgctcag gtatcacgta cattctatgc ccgcggccaa accggacagc agttgttgct
     1441 gggtgcttat tctgcattga gccgtgaagt tcagcgtggt aacgtgaaat tgtacactcg
     1501 ttatgaaatg ttggacgttg tgctgattaa ggataacgaa ggtgtggaac gcgcccgtgg
     1561 tatcatcgct cgtaacttgg ttacaggtaa gatcgaacgt tttgctgctc atgcagtagt
     1621 aatcggtacc ggtggttatg gtaatactta tttcttgtct accaacgcta tggcgtcaaa
     1681 tggatcggct gctatgcagg tttaccgcaa aggtgcttat tttgctaatc cttgttttgc
     1741 acagattcac ccgacctgta ttcctgtaca cggtgacaag cagtctaaac tgactttgat
     1801 gtctgagtca ttgcgtaatg acggacgtat ctgggttccg aaaaagctgg aagatgccaa
     1861 ggcattgcaa gcaggaacta aaaaaccgac tgatatacct gatgcagacc gtgacttcta
     1921 tctggaacgt cgttatccgg cattcggtaa cttggttcct cgtgacgttg cttcacgtgc
     1981 tgcgaaagaa cgttgcgacg caggtttcgg tgtgaacaac acaggtttgg ctgtattcct
     2041 cgactttaag tacgctatcg atcgtctggg tgaagatgta gttcgtgccc gttacggtaa
     2101 cttgttcgat atgtacgaag aaatcactga cgagaaccca tacaagactc cgatgatgat
     2161 cttcccggct atccactata caatgggtgg tatctgggtt gactatgaac tgatgacttc
     2221 tatcaagggt ctgtatgcta tcggtgaagc taacttctct gaccacggtg caaaccgttt
     2281 gggtgcatct gcattgatgc agggattggc tgacggttac ttcgtattgc cttacactat
     2341 ccagaactat ttgtcagacc agattcaggt tccccgtttc tcaacagacc ttcccgaatt
     2401 cgtagctgcc gaaaaggctg taaacgataa gatccagaga ctgatgaata tcaagggtca
     2461 tcgttctgta gactctattc acaaggagct gggtcacatc atgtgggact ttgtaggtat
     2521 gggacgtacc aaggaatctt tgactactgc tctggctaaa ctgaaagaag taagaaagac
     2581 cttctggagc gaccttcgca ttccgggtga agctaatgaa ttgaatgtag aacttgaaaa
     2641 ggcaatccgc ctggctgatt tcatcgaaat cggtgagctg atggcttacg atgcattgaa
     2701 ccgtgaggaa tcttgtggtg gtcacttccg tgaagaacac cagactccgg aaggtgaagc
     2761 acttcgtcac gatgacaagt tctcgtatgt agcttgctgg aaatacaccg gtgaaggaaa
     2821 agaacccgaa ttgatcaagg aagatttgaa ctatcagttc gttaaggttc aaactcgtaa
     2881 ctataagtct taattattaa ttgtatagaa atcatggata aaaatataag tttcacactg
     2941 aaagtttggc gtcagaaagg tcctaaagac aaaggacatt ttgatacctt ccaaatgaaa
     3001 gatattccgg gtgatacctc attcctggaa atgatggaca tcttgaacga gcagcttatc
     3061 aatgaaggta aagaacctat cgtattcgac cacgactgtc gcgaaggtat ttgcggtatg
     3121 tgctctatgt atatcaacgg acatcctcac ggacctgcta caggtgctac tacctgccag
     3181 atttatatgc gtcgtttcaa agacggtgac accattactg ttgagccttg gcgttctgcc
     3241 ggtttcccgg taatccgcga cttgatggta gaccgtagcg catacgacaa aattatgcag
     3301 gccggtggtt acgtgtcaat caataccggt ggtattcctg acgctaacgc aattcctatt
     3361 gcaaaaccta ttgctgacga ggctatggat gctgctgcat gtatcggttg tggtgcttgt
     3421 gttgctgcat gtaagaatgg ttctgccatg ttgtttgttt ctgcaaaggt cagccagttg
     3481 gcactgttac ctcagggtaa agtggaagct gcacgccgtg cgaaagctat gttgagcaag
     3541 atggatgaac tgggctttgg taactgtaca aacactcgtg cttgtgaggc agaatgtccg
     3601 aagttggttt ctatcagcaa catcgctcgt ttgaaccgtg aatttattgc tgcgaagctg
     3661 aaagactaat cacggttagt tttacttgat atttgagaat gccctgcctt tggtggggca
     3721 ttttttttgc ctggggcttc ttctttttct ctcttacgta tgtttctggg agaatcgcca
     3781 aagaacttct tacagaagtt ggagaaatgt gagagagatt cgaatccatg ttcgaagcag
     3841 atttcggaga tggaagcctc tgtatagcgc aattggtaga ggatactttc tttgcgctgc
     3901 ttcatcatcc attcataggc cggttcgttg aagatagcct tgaaaatacg gcggaaggtg
     3961 gtgacgctat agccgcccag ttgtgcgaag tcttctacag actttatttg cttgtggtgt
     4021 tttaatataa aatattcaaa gctgttggta tacttggaca aactgtgtac aatgggggaa
     4081 agctcatagt ctgtatagta gtgcgccagt agataataca gttctttacg cttgaattca
     4141 agcagttctt tacagatttt gtctatattc agataggagg taactccttc aaggaaaagc
     4201 tttatttcgg gctttatttt aagtggctcg gagatgagtg gcgggggcac gtttttcaat
     4261 atataggtat agcggtcata acagaaagct ttggggtcat cgaatgtgta cagaatacct
     4321 tccgagtctg tcatggccag tatttccact tttgatgcga tagcttgcag tacaaattct
     4381 ccgggattga tgatagtacc ggcatattct tcactattga tgagtatttg gcctttgagt
     4441 aagaaaaata agatattagt ttcacactta tgtgggggta agtggaaacc ttttttgtta
     4501 tgtgtgtaat ggatgctatt ctccactgct ttagggcatt gggtacaatc catcctttca
     4561 ttacagggca gaccagacat atatagatgt tagagacgct tgtgttcttt tttttgattt
     4621 gacaaatgta ggtcaaatat ggataatttg caataagttt caagaaaaag accgaagaat
     4681 cctgtttcca cttgtttgtc ttctgccgtt acggaaaacg atagcctgtg ggcatgagca
     4741 tagagggcta aatttgtgtg gccaaacaaa aagaagttgc aattgttggg aaagtagcag
     4801 aaagaaagta tctttgtgtg taccccatgg ggaggtatac cggctaaaac agcatagatt
     4861 atggaatttg tagtatcatc agataagaaa ttattgccct acggcatgat gaatttcgcg
     4921 gatatacgcc ttgatggtta ttattatgtg gacaagacca tgtatatccc gttgatagaa
     4981 cgctccaacc gttatttttt ctttatccgt ccgcgtcgtt tcggcaaaag tctgacgctg
     5041 aatatgctgt aacattacta tgatgtacga accaaggata aattcgacgc cctgtttgga
     5101 gacctctaca tagggaagta tcttacacgt gaccggaaca gctacttggt attgtatctc
     5161 aatttctccg gtatcattgg cgaactgcat aactatcgtg ccggattgga cgcacattgc
     5221 caaacctgtt tcgactattt ctgtgatatt tatgcggaat acctgccgca gggtatcaaa
     5281 gaacagttgg acgcaaagaa tggggcggta gaacaattag actatcttta tcatgagtgt
     5341 gagcgtgtcg gtcaggatat ttatcttttt atcgatgagt atgaccattt taccaatgcc
     5401 atcctttcgg atgccgaaag cctgcaccga tatacgaagg aaacgcacaa ggaaggatat
     5461 ctgcgtgcat tcttcaacaa gataaaatcc ggtacctatt ccagcatcaa acgctgtttc
     5521 attaccggag tcagtcctgt gacgatggat gtggttgttt ctaggggtat tttatgattg
     5581 aggacggctg attgtcaaca ggtaaaaatg ctccgcaaat gaaatcgcaa atgatagagg
     5641 ggatgatgcg gtgtttcatt gcggagcggg gaattgttat gtttatctgt atgtttgtcg
     5701 ggggatttgt aaattcatta atttatagtt tgttggtttc ttataataca ggagttttag
     5761 gagtttgctc gttatcagtg gcattccaat cttcatcata tgttgtgttt acactcattt
     5821 tttctgcacc aaccggtaaa gttagtatat agcggatact ttgcccatta gtccattctc
     5881 ctgttaaagc tacttctttt gatccgttaa agaatgttgc attatctttc tctgttttat
     5941 acttgactgt aattttagca tcagtaagag attgtgggta cagcattaat gaattattat
     6001 tttgtgtata atcataaata tcatctttgg ctgttacggt gttatcaaat gtatagctat
     6061 aaccactagc aggtgcactt cctgtgatat tccaatttcc accttttcct tcagttcctc
     6121 cgaatgtgta cgttgcggca ccaccttttg caccggtgat agttatgctt tcaactgtgt
     6181 aagtatagtt gctgtcagct agttttgcag caaagtttat acgggttaag atgtgttgga
     6241 atgtaaggtt taatgtatta tcacttggct tagttatatc tttggaataa gctactataa
     6301 tatctttctg atcggccggg gtatcaggaa gggtatagct gatggtggga taagcgctgg
     6361 aactagcagg tgctgtatag gttacatcat tggtatatcc aaaaaattgc atttctgtta
     6421 taggccaata aaaagtacca cttgttgtag cccaattacc ttgacctcct ttatattcta
     6481 tgccatccat atacgcgtta ccccatcctg aagtggcgat atcgctgctt ttaattatat
     6541 aggcatgtaa tttaaaagac gtgaaactac tattacttgt aacagtggcc cttgaactct
     6601 ttttgacaat cgtgtttact cctatctcat ttttactttt gggagttcca ttgtcaatac
     6661 catcaatctc attctgtgag caacttgtga ttgccaatgc agctaaagct gcaaataaaa
     6721 tcttcttcat atcctatgtg ttttaagtta ataattctat gactctttat tctatatttt
     6781 aaccgaccgg taattctaca ttcgtttcat catcccagtc actgacgttc ccatcaaatc
     6841 caccgccact ttcatcagga ggaatctcta catcatccac cacaatcttc tcatcatccg
     6901 gaagttcgat ctctatctcc ggctcttgag gtttttcatc gccttctccc ggctcgtctt
     6961 tatcttcagg aggttttacc gcttccgtta tttctacttt cgcttcctgt ttggaaccat
     7021 ccacttttac tataatcaag ttcagaaact gagtgatatc ggctcttgct tgcgtcagtt
     7081 tgggatgccc aaagcaggta aaactccctt ttatagcccc attcccttta ctggtttcac
     7141 aataaatagg agcgaaccgg cataggctgg ctcctttgcc caggtggtaa cattcagcca
     7201 ttccggaaac actgcccagg atggatgcaa catttttcag cccttctgtc tttattgaaa
     7261 aagtgtaagt ggttaccaca gattttggtt ttacctctag tgtcggtaat tcttcctctt
     7321 ttcctatctc tacatcgtcc agggttgcta cataaaaatt atccggtccc cataccatgt
     7381 ctttcgtttc ctcggcaccc agtcccgtac agtttcctgt acatgccatt attgtttcgt
     7441 agctaccttc gtcttttatt tgcactactt cggtgtcata attgtaaatc actgccgaat
     7501 aatgtcccgg aggtactttt atttctccgc ctttcgccgg taagtaggta tcaatcttcc
     7561 ttccttggcc gtccttggga tagaagatga tccggactcc ttccggcaga cggtcggtta
     7621 ctccttccca atttagacgg atgtttattc ctgttacggg gtaatcgtcc agaatctcgc
     7681 ggcggctgca tcccactaaa gtcaatagtg aagataaaag tacaagaatt gcgtaccttg
     7741 tctttttcat tttcttcctc ttttcttggt tatcaaccat accaacgaaa tttttgcttt
     7801 cgtagggcct ataaaggtgt aatttccgct actcatccag actagtgatc cctcataggg
     7861 agtatatttt tgatattccg tggtcagata gcctatgcct aggctgaatt ccaatgccag
     7921 atgtcgtgac aacaaagtgg aatatccata agtgaatcct gccgcaccgt aatatttacc
     7981 ttggtagccg tttcctttaa actgaaagtc gtagatacct ccctcgatat acaatccaaa
     8041 gaaatgtccg ttcaatcggt tgtgtagttc acggttgccc agccagtaac ggctttctat
     8101 tcctcccgaa atcagttggt agcagatttc tttactgctg ttggaccacc aggggctttt
     8161 atattccata ttcactgacc atctctttcc tacaggaatt tctatttcta tattaggtgc
     8221 cagtgccaga tcgtacaata aattattttt cagcgcaagc actgtgttgt cgactgtctg
     8281 gactcttctt gctgcctttt ctttgggctt ttctccccgt ttctcttttg tctctttttt
     8341 cttttctgcc tttattactg ttttttctgt ttctattatt acttgtgttc tttccttctg
     8401 tggaagtact tgcatcgtca ttggcgtaac ggtcgtttcc ctgtcaatcg gtatgaattc
     8461 agtttcttct atccttgctg cctgttctgc ggaggagttt tttcctccgt tttcttccgg
     8521 ataagacagg cagactctta tctctgtccg tctgagttcc ggtagcactc ggtcagaaat
     8581 atactgataa ggtatgccgg cgtccaggcg ttgcaagaaa tcttgcattt ttacgggatt
     8641 gtcatggtga taatctatca atgccaatac atcttcccgg tcggggacca gtctgtcgtc
     8701 cagtatcagt ttccgtaagg catccccgta ctcttctcct ttgcggatac agatttgggc
     8761 ggtattgacc tgcggatatt tcccacataa gaacactttt acttcctcac ttcttttttg
     8821 tcccagcggt atgccctgtt cttttttacc attatataaa tccggtgaaa ccagaataat
     8881 ggaattaaga tggatgctgt gggcaggatt ggcaagtaga gaatccaata ccgtcagcgt
     8941 tttaccgttt ccttggtaat ccttgtctat ctgtcgggca ttcaggtcaa aatagagcgt
     9001 catgtccaac gtggtgtctt tggggttttc gtactctatt gtccgggcat aaatgctatt
     9061 tggcagtagg cacaaaagca caaatatgct gaatatagta gtgcgttttt ccatgaatta
     9121 ccattatgta tgaagcaaat ataggtgata aaatctgaaa aaagacttat taaatgttct
     9181 attttcggac ttgaaagggt ttgtgaagcg attggataga atttgcaagt tttggcggtt
     9241 ggataatgag aagggcaggg gacttacttt tattttggat gaataacatg agggaatact
     9301 ttctttttgt tttttacttt ccagcagaca ggaatgaatc attctatgat attgatagaa
     9361 taatgtttca tattcctttt ttaaccccgc ttttcttgtc ggattgtaat actgtgtgcg
     9421 aaaacgattg tatttgtgaa ataatactaa atgaaaagca aaaatgaacc aaatatttgg
     9481 aggtattgag tgtaagttgt acatttgtca tgtgattttt ttcatagtat tagatttaag
     9541 gttaacaaag gttggagcaa ggcgttgctc ctttcttttt ttagtacctt ctgtttcttt
     9601 ccattctcct aatcatcagc tccttaatgc cgttgatttt ttaaaatatt ctgtttcttg
     9661 ttttcatcca atggatttta tgttatcttt gtgtcaatgt aaactaacta acaatctaca
     9721 tgaaaagaca cacaaacctt ttatgcttgg gggctgctgt cgcattgctg aatgcttgcg
     9781 ccccggtggt gaacgctcct gagcctgttc ttcctgttcc cgagaaaaag caggtggact
     9841 ggcagaaaat ggaaacttat gctttcgtgc atttcggact gaatactttt aatgaccgcg
     9901 aatggggtta tggagattct gaccctgcca cgtttaatcc ggttaaactg gactgcgagc
     9961 aatgggtgaa aacttttgtg gcggcaggga tgaaaggagt tatccttacg gcaaaacacc
    10021 atgacggatt ttgtctgtgg cctacggggc tgaccgaata ttgtatccgt aacacacctt
    10081 ataaggatgg aaaaggagat atcgtacgtg acctttcgga ggcttgtaaa aagtatggta
    10141 taaaattcgc tgtctatctc tcaccgtggg acaggcatca ggccaattat ggaactccgg
    10201 aatatgtgga ttatttctat caacagttac acgaattgct gacccattac ggtccggtgt
    10261 tcgaaatttg gtttgatgga gctaatggag gggatggctg gtatggcgga gccaaagact
    10321 cccgtaccat agaccggaaa aattattatg attatgcgcg tgcatacgag atgatcgaca
    10381 aatatcagcc gcaggccgtt gtcttctcgg atggcggacc cggatgccgt tgggtaggta
    10441 acgagaatgg ctttgccgga gctacaaact ggtctttcct gcgtgccgga gaggtttatc
    10501 cgggatatcc taaatacagg gaactgcaat acggtcatgc agacggcaat cagtggacgg
    10561 ctgccgagtg tgatgtgtct atccgtccgg gctggtttta tcatccggag gaagatgaca
    10621 gggtgaagac ggtggagcaa ttgacagacc tttattaccg cagtgtgggg cacaatgcga
    10681 ctttgttgct caatttccct gtaaaccggg atgggctgat tcatccggta gattcggcga
    10741 atgcggttga cttttataag aatgttcaga aacagctggc aaacaatctg ttgaaaggtg
    10801 ttcttccgat agtttccaat gaacggggtg gaaagtacac tgcaaaggcg gtgacggatg
    10861 gagaatatga tacatattgg gctacggagg atagtgtcac atcggctgtc atcgagtttg
    10921 aatggccggc tccgcaaaag gtgaaccgta tgctgttgca ggaatatatt ccgttggggc
    10981 agcgtgtaca atcctttgtg gtggaatata ataaagaagg ggagtggctg cctgtgaagc
    11041 tgaatgaaga gacaaccaca atcggttata aacgtttgct tcgttttgaa acagtcacta
    11101 cggacaaact tcgtataaac tttatggaat cacgcgcttg cttgtgtatc aataatatag
    11161 aggcttatta tgcaggagaa accccggatg tgtttactgc gaaagcggaa gaactgaaaa
    11221 cgtatccgtt tacattgccg caggtagatg aggcggaagc cggaaaatgt gcggataaag
    11281 atgccgccac gacttgcttt gtggatggca atacgctttt gatagattta ggtacggaac
    11341 agactgtttc ttccttccat tatctacccg atcagagcga gtataacaaa ggactgatag
    11401 ctgcttatga gatttcagtg ggtatggagg ccaatgctgt gaatcaagtg gtgagcagcg
    11461 gggaattctc gaatatcaag aataatccga ttctccaatc ggtttatttc actccggtaa
    11521 cggctagata tgtattgctg aaagcagtga ggatggtgga aaacgagagt ccgatgggct
    11581 ttgccgaatt aggagtgcaa tgaccatgta tcaatatact catgtgtccg ttcacaatac
    11641 agctaccgta tgtcaatgag tacatgagta tattgataca tggttacatt attaatcggt
    11701 acactcctcc tgccagtgct cgtatcaccc ctttcatttc taattcaaac agtaatgcac
    11761 tcattcggtt tacaggtatg ttggtgtcta tcaccaatgt gttgatttgt aatccttccg
    11821 gtattttgcc gagtcgtttt actattcgtt cttcttcctc gcttaaatca gggaacaatt
    11881 cccgttgtac tgttttctca gttttggggc tgctttccca tcccataccc ttcactaaat
    11941 cctcggccga tgtgataagc actgcctggt ttttccttat cagattgttg cagcctatgg
    12001 aatattcatc attgcatcgt cccggaaagg caaaacagtc ccggtgataa ctttccgcca
    12061 gttcggcggt gatgagggct ccccctttgg cggcggactc gataacgacg gtggcgtcac
    12121 tcatacctgc tacaatgcgg tttcgtttca cgaaattttg cctgtcgggg ttggttccgc
    12181 ttgtaaattc ggtcagcaaa cctccctgtt ccaacatgct gacggctgtc ttccgatgtt
    12241 cggcaggata aatgcggtcc agtccgtgtg ccagcacgcc tatggtcttg aaatgattct
    12301 gcagggcggc gcgatgcgca tggatatcaa tgccataagc cagcccgctc actatcaagg
    12361 tgtttgggca caataccgac aagtcggcaa ggaaacgggt gcagatatcc tgcccataag
    12421 gggtggcatg acgggttcct actatattaa taatatgcag cgtgttcaga tcggcatttc
    12481 cccgataaaa taaagctagc ggagcatcat cacattcacg caaacggctg ggataacctt
    12541 catcatttaa ggtgaggcag cggatatgat ttttctgaca gaaagttaat tcctgctctg
    12601 cacgccggaa agcttcggag ttattcaacg cagtaatgat cttttcgctt actccgggga
    12661 ccaattgtga cagctctttg cggtgttcga aaacacgggt ggcgcttccc agactgctca
    12721 ccagtctgaa tgcgcctgtc agtcccaatc ccggtatccg ggttagggcc aggctgcaaa
    12781 tttgttcgtc ttgtgtcatt cgctcaggta gggtgcgaaa gtctcgtcaa atagagcgct
    12841 gtcccctaat ctgccgttta ccacgcatac tgattctaca gtggccttga cagtcacttt
    12901 catatcgggc agacggaaga tgtcctgata gaacacatat ttaatacctt cttttttcag
    12961 atagagttta gaaacgaatt cgtcaccgct gcgcagcgga gttttgaacg ccatggtgag
    13021 ccgtgccact accgggtcca ctccttcctc gtgcagacgg gcgaagctga tacctacgga
    13081 tgtgagaaac tcatggcgtg tatgttccag ataatgttga tagttggcat tgttcacaat
    13141 accctgcagg tcgcattcat aatcgcgtac cttcatcttc agttcataaa tatacttttc
    13201 cataaagcaa aggtataaga aaaatgtgtt actttgcatc taaactaaaa aaaagaagtg
    13261 aatgaaacta tatgctgcgc ctttgcaagg ttttacggaa gctccctgga gaaactttca
    13321 tgaggaagtt tttggtggaa tagatgcgta ttatactcct tttgtacgaa tagagagagg
    13381 aggattccgt aacagggatg tacgggacat tgctcccgaa aacaatacgg tttcccatgt
    13441 agtgcctcag ctcatcgcgt ccactcctgt cgagctggaa cggttggccg ctttgtttac
    13501 agagaaagga tataaggaag cggattttaa tatggggtgt ccttttccgc tggttgcaag
    13561 aaagcacaag ggctccggca tattgcctta tcctgccgag gtagaagctt tattgaaaga
    13621 gttgacacat tatcctgaac tgagtttttc ggttaagatg agattggga
//
