LOCUS       gnlProkkaOMMGNOIP_31   10525 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OMMGNOIP_31.
ACCESSION   gnlProkkaOMMGNOIP_31
VERSION     gnlProkkaOMMGNOIP_31
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:05:00
            Original ID  :: gnl|Prokka|OMMGNOIP_31
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10525
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10525
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1237:5525]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1238..5525
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10525
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10525
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(2..1177)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.2e-29, bitscore:
                     95.1, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKIIHNVLAKGGLTIFNLILPLAVMPYIYRVLDPHDLGMIEYA
                     TAIVTYFSIFGMLGIYNYGLREMSSIRNNLNSCAFLYRQLFTIGVLSNIFSATCLLLLS
                     FFMDKLVKDIVYIQLLLIVSQIFYVEWVNEAFERYSFITLKTILVRGLGYLSIFGLVTS
                     SNDYKTYVWILSITVFINYFISYLYVKKKLPIESVQVDWNFIKKIIFALFLILLLNNTN
                     LLYTLLDRFMLGLKSDIYVAYYGVGQKLSDMLKAFLTIVVVVTIPRMSLQLNQNKERYL
                     ENINHLISFLFLLTLPIASLFFCLSKEIVILFAGENYLEAIPSLKIFAIRIVVIVLEAV
                     LYNQIIFLYRREKDLLKLNALCGCLNLGLNGVLYSFLNPFLAILTTLVSELV"
     CDS             complement(1238..1948)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.1e-16, bitscore:
                     52.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAVIMAAGMGTRFGKYTEQIPKGFVEVCGKPMIERSIETLIS
                     CGIERIVIGTGYKHEVYDFLKKKYPMIETCFSPLYAETNSMYTLYNTQGLIGSDDFLLL
                     ESDLVFETKAITELMNCGKPDVMLATPITKFQDQYYVEFDTKHHLTACSTQKENLNVKG
                     ELVGIHKISSTFFKEMCKDYGRILSEQPKLGYEYELLRISMSTLPLFVLVVEGLKWYEI
                     DDLMDLAYAEIFFK"
     CDS             complement(1961..3079)
                     /NRPS_PKS="Domain: Aminotran_5 (31-334). E-value: 3.5e-31.
                     Score: 100.3. Matches aSDomain:
                     nrpspksdomains_ctg31_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.4; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.8e-07, bitscore:
                     20.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.7e-29, bitscore:
                     93.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIKRNILLNPGPATTTDTVKMAQVVPDICPREKEFVGMMKTLRT
                     NLLKVAHGIPGKHTAVLFCGSGTINIDVCLNSLLPKDKKVLIINNGAYSDRAVEVCRYY
                     GLSHINLRFSVYERPDLHEIESILKKDSDIFLVYTTHHETGTGLLNPIREIGALAHRYG
                     CVFITDTTSSLGMIPFDIEKDNVDFCMASAQKGLQSMTGLSFIVGNEEIICKSKEYPKR
                     SYYCNLYMQYEYFEKTGEMHFTPPVQTIYATCQALKEYFEEGEENKFARHRRVFDAIHS
                     GIEELGFKYVIDKQWQSGLVVSVLYPNHPNWNFDKVHNYCYERGFTIYPGKITTTNTFR
                     LCALGAIDESDIKSFFSVLKDALEHFNINVFY"
     aSDomain        complement(2078..2986)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg31_3_Aminotran_5.1"
                     /evalue="3.50E-31"
                     /label="ctg31_3_Aminotran_5.1"
                     /locus_tag="ctg31_3"
                     /protein_end="334"
                     /protein_start="31"
                     /score="100.3"
                     /tool="antismash"
                     /translation="REKEFVGMMKTLRTNLLKVAHGIPGKHTAVLFCGSGTINIDVCLN
                     SLLPKDKKVLIINNGAYSDRAVEVCRYYGLSHINLRFSVYERPDLHEIESILKKDSDIF
                     LVYTTHHETGTGLLNPIREIGALAHRYGCVFITDTTSSLGMIPFDIEKDNVDFCMASAQ
                     KGLQSMTGLSFIVGNEEIICKSKEYPKRSYYCNLYMQYEYFEKTGEMHFTPPVQTIYAT
                     CQALKEYFEEGEENKFARHRRVFDAIHSGIEELGFKYVIDKQWQSGLVVSVLYPNHPNW
                     NFDKVHNYCYERGFTIYPGKIT"
     CDS             complement(3084..3857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.8;
                     E-value: 4.3e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-21, bitscore:
                     68.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDLLNAMQIPFVILNAEEDKALRQIHDIIISAKDKSIPHAIII
                     RKNIFGKYKLLNEQKNDCPLSREEALKLVVDYLEATDLVVSTTGKLSRELFEYREAEGE
                     GHECDFLTVGSMGHSSSIALGIALANSERRVFCLDGDGAFIMHMGAIGNIGYLSPKNYF
                     HILFNNGSHESVGGQPTIGFQLDIPAIAKACGYRTVFSLTTKDEIKEILQQTKIMEGPV
                     LIELKVKVASRDDLGRPTTTPLENKFHFMEFLKNK"
     CDS             complement(4224..5525)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 220.3;
                     E-value: 5.2e-67)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg31_5"
                     /sec_met_domain="CTP_transf_like (E-value: 4.4e-12,
                     bitscore: 37.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-121, bitscore:
                     396.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.9e-65, bitscore:
                     209.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQIYIGMTADIMHPGLINIINEATKFGDVIVGLLTDKAIAEHK
                     RLPYLTYEQRKKIVENIKGVSKVVPQEEWSYINNLKRLKPDYIIHGDDWKTGVLCEIRE
                     QVYDVMNKQGGTVIEIPYTQGINSSSLNRDIKSIGTTPDVRMKTLRRLINAKSIVRILE
                     AHDGLCGLIIENLEIQKGDRLEVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKIGLKKNSLFGTDAIQTQDT
                     IEGFCNKIKAGKEAQVTNDFMIIARIESFIAGKSMCDALERAYAYVEAGADGIMIHSKN
                     KSGEDIKEFCITFRQKYAHVPIVVVPTTYDHIYESELHTWGVNVVIYANHMLRAAYPAM
                     LQVAKTILENERAKEVRPLCMPIKEILELIPGTK"
     CDS             complement(5605..6756)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_6"
                     /sec_met_domain="Epimerase_2 (E-value: 5.8e-124, bitscore:
                     404.9, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIMLVFGTRPEAIKMAPLVKEFQKYPEEFKTIVCVTGQHREML
                     DQVLHIFEIIPDYDLNIMKPGQDLYDVTARVLIGMRDVLKEVQPDVVLVHGDTTTSTAS
                     ALAAFYQQIPVGHVEAGLRTHNIYSPWPEEMNRVITGRIASYHFSPTPLSRQNLLDEGV
                     RESAITVTGNTVIDALYMVVDKIKSDKRLDEELKGILKTAGYDINRLLDGKKLVLITGH
                     RRENFGDGFVSMCRAIQTLTKKYPNVDFVYPMHLNPNVRKPIYEVFGEDLSNLGNMFFI
                     EPLEYLSFVYLMEKSTIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALEAGTVKLVGT
                     NYDKIVKEVSALLDNKAHYEEMSKAVNPYGDGTACVRIVNILE"
     CDS             complement(6772..7977)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 385.1;
                     E-value: 6.1e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg31_7"
                     /transl_table=11
                     /translation="MKACFMGLGYIGLPTAIIAAKHGIQIIGVDINPKVVEMTNQGKLH
                     IIEPGMQELLQEVVTTGQLKASTTPEVSDAYFMVVPTPFKGNHEPDISYVEAATRAVIP
                     LLKEGDLYVIESTSPVGTTDKMCDLIFGLRPELRDKIYIAYCPERVLPGNVIYELVHND
                     RVIGGLNEASTDRATEFYSKFVRGTLHRTNCKTAEMCKLTENSSRDVQIAFANELSLIC
                     DKAGINVWELINLANKHPRVNILQPGCGVGGHCIAVDPYFITAEFPMESKIISTAREIN
                     NYKAFWCAEKVQNAMLKFELEYHRKPTIAMMGLAFKPDIDDLREAPAKYITTKVMQSCN
                     NADILVVEPNVQEHNVFKLTDYKEAYEKADIVVFLVAHSVFKSLPYNDRKVILDFCGIY
                     KK"
     CDS             complement(8555..9088)
                     /locus_tag="ctg31_8"
                     /transl_table=11
                     /translation="MTEQQKYWFAARTRDKQEFTVRKSLDRLKSEEHLDLDYYLPTRFV
                     ISQLKYRRKRSEVPVIRNLVFVHSTKQTACDISNIYNVPLFYMKDLATHSMLVVPDKQM
                     EDFMFVMDLNPDGVSLDSEILTVGHKVKVIKGELSGIEGEVAIEANKTYVVIRIKDLLT
                     ASIKVPKSYLKIIG"
     CDS             9731..9964
                     /locus_tag="ctg31_9"
                     /transl_table=11
                     /translation="MKQSFNDHKQGCSWPLGVTNSKAFTDEVRSPRLLRTRCKRIVQQL
                     KRHQTPLFIVGQTRKCRKTTLTDLCNPRAVLY"
ORIGIN
        1 aaacaagttc acttaccaat gttgtcaata ttgccagaaa gggattcaag aatgaatata
       61 aaacaccatt taaccctaaa ttaagacatc cacataaagc atttaacttg agtaaatctt
      121 tctcacgacg atataaaaat attatttgat tatacaaaac agcttccaag acaataacca
      181 caattcgtat tgcaaatatc tttaaagatg gaatagcctc taaataattt tcaccagcaa
      241 ataatataac aatctctttt gataagcaaa aaaataaaga ggcaattggt aaagttaata
      301 aaaataaaaa acttatcaaa tgatttatat tctccaaata tctttcttta ttttgattta
      361 attgtagaga cattctaggt atagtaacaa ctactacaat tgttaaaaaa gcttttaaca
      421 tgtctgaaag cttctgcccg acaccataat atgccacata tatatcactt ttaagcccca
      481 acataaatcg gtctaataat gtataaagca aatttgtatt attcaataat aatatcaaga
      541 ataaagcaaa tattatcttt tttataaaat tccagtcaac ttgtacagat tctataggta
      601 atttcttttt tacatataaa tagctaataa aataattaat aaaaactgtg atagacaata
      661 tccaaacata tgtcttataa tcattcgatg atgttactaa tccaaatata gacaaatatc
      721 ctaggccacg taccagtatc gtcttcaatg ttatgaaaga atatctttca aacgcctcat
      781 taacccattc tacataaaaa atctgagaaa caattagcag taattgtata taaacaatat
      841 cttttactaa tttatccatg aaaaaagaca atagcaacag acatgttgcc gaaaatatat
      901 ttgacagaac tccaatcgta aataattgtc tatacaagaa agcgcatgag tttaaattgt
      961 tacgaatcga gctcatttca cgtaagccat aattatatat tcccaacatt ccaaatattg
     1021 aaaaataagt aacaatagct gtcgcatatt ctatcattcc caaatcatga ggatccaaca
     1081 ccctatatat gtaaggcata acagctaaag gaagtattaa attaaaaatt gtcaatcccc
     1141 cctttgccaa aacattatga ataattttca aacccatgtt aaatatgaac agttatctat
     1201 attcaacaaa gtaacatcta tggaccttct aaagattcta tttaaaaaat atttcagcat
     1261 aagctaaatc catcagatca tcaatttcat accatttcaa tccctctaca actaaaacaa
     1321 agagaggtaa tgtactcatt gaaatacgaa gtagttcata ttcatatcca agtttaggct
     1381 gttcagaaag aatccggcca taatctttac acatttcttt gaaaaaagtg ctagatattt
     1441 tatgaattcc taccaattca ccttttacat tcagattctc tttttgagta gaacaagctg
     1501 tcagatgatg ttttgtatca aattccacat aatattggtc ttgaaatttt gtaataggag
     1561 ttgctaacat gacatcaggt tttccacaat tcatcaattc agtaatagcc ttcgtttcaa
     1621 atactaaatc cgattctaat aataagaaat catcactacc tataagtcct tgagtattat
     1681 aaagtgtata catactatta gtttcagcat aaagaggact aaagcaagtt tcaatcatag
     1741 gatatttctt ttttagaaaa tcataaactt cgtgtttata tcctgtgcca attacaatac
     1801 gttctattcc acaagatatt aaagtttcaa tactacgttc tatcattggt ttaccacaca
     1861 cttcaacaaa tcctttagga atctgttctg tatatttccc aaaacgagtt cccatacctg
     1921 ctgccataat tactgctgtc tttatcattc caatatggtt ttaataaaat acattgatat
     1981 taaaatgttc taaagcatct ttcaaaacag aaaaaaaaga cttaatatcc gattcatcta
     2041 ttgctcctaa tgcacaaagt cgaaaagtat ttgttgtagt tatttttccc ggataaatgg
     2101 taaaaccacg ttcataacaa taattatgta ctttgtcaaa attccaattt ggatgattag
     2161 gataaagaac agacacaacc agccctgatt gccattgctt atcaataaca tatttaaaac
     2221 ctaattcttc tatgccagaa tgaatcgcat caaacaccct tcgatgtcgt gcaaatttat
     2281 tctcttcgcc ctcttcaaaa tactctttca aggcttggca agtagcatag attgtctgaa
     2341 caggaggagt aaaatgcatt tcacccgttt tctcaaaata ttcatattgc atataaagat
     2401 tacaataata agaacgttta ggatattctt ttgacttaca tataatctct tcattgccaa
     2461 ctataaaaga aagtcccgtc atcgattgta atcctttctg ggcagaagcc atacaaaaat
     2521 caacattatc tttctctata tcaaaaggaa tcatacctaa ggaagaagtc gtatctgtta
     2581 taaatacaca accataacgg tgagcaagtg caccaatctc acgaatagga ttcaacaaac
     2641 cagtgccagt ttcatggtga gttgtataaa ctaaaaagat atcagaatcc ttttttaata
     2701 tggattcaat ctcatgcaga tcaggacgtt catacaccga gaatctcaaa ttaatatgag
     2761 ataaaccata atatcgacaa acttccacag cacgatcact ataagcacca ttattgataa
     2821 tcagcacttt tttatcctta ggtaacaaag agttcaagca aacatcaata ttaatagtac
     2881 ctgagccaca aaacaaaaca gcagtatgtt taccaggtat accatgggca acttttaaca
     2941 aatttgttcg caatgttttc atcattccta caaactcctt ctcacgagga caaatatcag
     3001 gaacaacctg agccattttc acagtatcag tggtcgtagc aggccctgga ttcaacaaaa
     3061 tatttctttt aatctgcata tacttattta ttttttaaga actccataaa atgaaactta
     3121 ttttcaagag gcgtagtcgt aggccttcct aaatcatcac gagaagcaac ttttactttc
     3181 aattcgatca aaaccggtcc ttccattatc tttgtttgct gcaaaatctc ctttatctca
     3241 tcctttgtcg taagcgaaaa aacagttcga tatccacatg cctttgcaat agccggtata
     3301 tctaattgaa aacctattgt aggttgacca ccaacagatt catgcgaacc attgttgaac
     3361 agaatatgaa aatagttttt gggagacaaa tagccaatat tgccaatagc tcccatgtgc
     3421 ataataaaag cgccatcacc atctaaacag aaaactcttc tctctgaatt agcaagtgct
     3481 atacctaaag caatagaaga gctatgcccc attgaaccta cagtaagaaa atcgcattca
     3541 tgcccctctc cttctgcttc acgatattca aacaattcac gagacaactt acctgtagta
     3601 gatactacta aatctgtagc ttccaaataa tcaacaacta attttagggc ttcttcacgg
     3661 gataaaggac aatcattttt ttgttcattt agaagtttat attttccaaa tatatttttt
     3721 cgaattataa ttgcatgagg aatggattta tctttagcag aaataataat atcatgtatc
     3781 tgcctcaatg ctttatcctc ttctgcatta agaattacaa aaggaatttg cattgcattc
     3841 aacaagtcca aagtcacttc accttgtttt tcatgctgtg gttcatcttt tactccaggc
     3901 tctccacgcc aaccaatcat taaaattatc ggtaagctat aaaccttttt atctgcaagt
     3961 gaaagcaaag gatttaccgc attacctatt cccgaatttt gcatgtaaac caaagacaaa
     4021 tttcctgagg ctaaataatg tcctgctgca atactgacag ctgtaccttc attggcagcg
     4081 ataacatgtt gctccttaaa agtatgatcc gttatatacg cacaaatatc ttttaagagc
     4141 gaatctggaa ctcctgtaaa aaaatcaatt ccgtttgcta aaagagcatg atatactttc
     4201 tcaacgttta ccatataatc tatttattta gttcctggaa taagttccaa tatttcttta
     4261 ataggcatac acaaaggacg cacctctttc gcacgctcat tctctaaaat agtttttgcc
     4321 acctgcagca ttgcaggata tgcagcacga agcatatgat tagcatagat aaccacattt
     4381 accccccacg tatgcaattc actttcataa atatggtcgt aagtagtggg aacaacaaca
     4441 atagggacat gagcatattt ctgacggaaa gttatacaga attcttttat atcttcacct
     4501 gacttatttt tactatggat cattatgcca tcagcaccag cctctacata agcatacgcg
     4561 cgttcaagag catcacacat agatttaccg gctataaaac tctcaatacg agcaattatc
     4621 ataaaatcat tggtcacttg cgcttctttt cccgccttaa ttttgttaca aaaaccttca
     4681 attgtatctt gcgtttgaat tgcatcggtt ccaaaaagtg aatttttttt caagcctatt
     4741 ttatcttcta taattacagc agaaattcca tgacgttcta aagtacgaac cgtaaacaca
     4801 aaatgttcaa ttttgcctcc tgtatcgcca tcgaaaataa taggcttagt agtacattcc
     4861 aatatattat tcaaatcctg aagacgagta gttaaatcta cagcctcaat atcaggttta
     4921 cctttgctcg ttgagtctgt taagctactg gaccacatac catcaaaaac ctccaaacgg
     4981 tcaccttttt gaatttccag gttttcgata attaagccac ataagccatc atgagcttcc
     5041 aatatacgca ctatagactt ggcatttatc aaacgacgaa gagtcttcat tcgcacatca
     5101 ggagtagtac caatagactt aatatctcta tttaatgaag aagaatttat cccttgtgta
     5161 taaggtattt ctatcactgt cccaccttgt ttattcatca catcataaac ttgttctcgg
     5221 atttcacaca gaactcccgt cttccaatca tcgccatgaa ttatataatc tggtttcaaa
     5281 cgtttcaaat tattgatata gctccactct tcttgaggaa caactttaga aacccctttg
     5341 atattctcaa caattttttt acgctgttca taagtcaaat aaggtaaacg tttgtgttca
     5401 gcaatagctt tatctgttag aagccctact attacatcac caaattttgt agcctcatta
     5461 attatattaa tcaagccggg atgcatgata tcagcagtca tccctatgta aatttgttta
     5521 ttcattttta tctatttata caaataatac attatctctc agacgcaaaa attcaatttc
     5581 aataatattc taattagaat tatttcattc taaaatattt acaatacgaa cacatgccgt
     5641 cccgtctcca taaggattca ccgccttgct catctcctca taatgtgcct tattatccaa
     5701 tagagcagag acctccttta caattttatc ataatttgtt cccaccaatt tcaccgttcc
     5761 agcttccagc gcttccggac gttctgtcgt atcacgcatt acaagtaccg gcttcccaag
     5821 tccgggagct tcttcctgaa taccaccgct atctgtcaaa actatagtgg atttctccat
     5881 cagataaaca aaagaaagat actctaaagg ctctatgaag aacatattcc ctaaattgga
     5941 taaatcttcg ccaaatacct cataaattgg tttacgaaca ttgggattta aatgcatcgg
     6001 atagacaaaa tcaacatttg gatatttctt tgtaagagtc tgaatagccc ggcacataga
     6061 aacaaatccg tcaccgaaat tttcacgacg atgacctgtt atcaagacta atttttttcc
     6121 atctaacaag cggttgatgt cataaccggc agttttcaaa atgcctttca gctcttcatc
     6181 aagcctctta tcactcttta tcttatctac aaccatgtaa agtgcatcta ttactgtatt
     6241 accagtcact gttatagctg attcccttac accttcatcc aacagattct gacgactcaa
     6301 aggagttgga gagaaatgat aactggcaat acgccctgtt atcactcgat tcatctcctc
     6361 cggccaaggg ctatatatat tatgagttcg aagtcccgcc tctacatgtc ccactggaat
     6421 ctgctgataa aaagcagcca atgccgaagc cgtagaagtg gttgtatcac catgaaccaa
     6481 aacaacatct ggctgtacct ctttcaaaac atcacgcata cctatcaaaa cacgagctgt
     6541 cacatcatac aaatcctgtc ctggtttcat aatattcaaa tcataatcag gaatgatttc
     6601 aaatatatgc aatacctgat caagcatttc gcgatgctga ccggtaacac atacgattgt
     6661 cttgaactcc tccggatatt tctgaaattc tttcaccaga ggagccatct ttatggcttc
     6721 gggacgagtc ccgaaaacca acataatctt cttcatgcta taagctattt attatttctt
     6781 gtaaattccg caaaagtcaa gaattacttt ccgatcatta tatggcaggg atttaaatac
     6841 agaatgagca accagaaaaa cgacgatatc agccttctca taggcttctt tataatctgt
     6901 aagtttaaat acattgtgtt cctgcacatt aggttccact actaaaatat ctgcattatt
     6961 acagctttgc atcactttag tagtaatata cttggcagga gcttcacgca aatcatcaat
     7021 atcgggttta aaggccaatc ccatcatggc aatggtaggt ttacgatgat attccaattc
     7081 aaacttcaac atagcattct gcactttctc tgcacaccag aatgctttat agttattgat
     7141 ttcacgagcg gtagatatga ttttagattc cataggaaat tcagccgtaa taaaataagg
     7201 atcaaccgct atacagtgtc ctccaacacc acaaccaggt tgaaggatat tcacacgggg
     7261 atgcttgttc gccaagttaa tcaattccca gacattgatt cctgctttat cacaaatcag
     7321 agagagttca ttggcaaaag ctatctgtac atcacgggag gagttttctg tcagtttaca
     7381 catttctgcc gttttacaat tagtgcgatg gagcgttcct cgtacaaact tactataaaa
     7441 ctcagtagcc ctatctgtag aagcttcatt caaaccgcca atgacccggt cattatgaac
     7501 taactcataa atgacgttcc caggaagaac acgctccgga caataagcaa tataaatttt
     7561 atctctcaat tccggacgta atccaaatat caaatcacac attttatcag tagtacctac
     7621 cggtgatgta gattctatga catacaaatc tccctctttc aacaaaggaa ttacggcacg
     7681 ggtagcagct tccacgtaag aaatatcagg ctcatgattt cccttaaaag gagtaggtac
     7741 caccataaaa taggcatcac tcacttctgg agttgttgaa gccttcaact gaccggtagt
     7801 aacgacttct tgaagaagct cctgcatacc tggttcaatg atatgcaact taccctgatt
     7861 agtcatttct acaactttgg gattaatatc aaccccgata atctgaattc cgtgtttagc
     7921 agcaataatc gcagtaggca ggccaatata acccaacccc ataaaacatg ctttcatatc
     7981 aataaaagtt atctattttt tatgatttct ttatcacact caaatcctat tctacttcct
     8041 caaacgggta tggattctct tcgatatttt tcaattcttc aatgatttca gtttgttcca
     8101 aagtcaattc atctctattc caaccttcaa taatcgcatg agcttcctga agcaaaactt
     8161 cctcataaat ttccccataa caataagtta gtaaacggac tttaagcaaa gaagcaggca
     8221 actgctccaa aacaagacaa atccgattca ataccatttg tttcttttgc tccttatccc
     8281 catcatcata aatagtagca ttatatccca tcaaaagagc cagacacaaa ttcgcctctt
     8341 cctcaacatc ggaactttga gcagaaaaaa gagaatcgga cttaacaagc acttccttat
     8401 tcaaccggca aaaattgtcg gaatagaccg gctcaccgtc cataccaaga tacatcagct
     8461 catgagctgc atgctgaagc tcaagagcac gggaagttaa atcattcatt attatgatat
     8521 atgataaaaa tataagatta tacttattta gaagtcaccc gattattttc agataggatt
     8581 tggggacttt gatacttgcc gtcaaaaggt ctttaatacg gataacgacg tatgttttat
     8641 tggcttcgat ggcaacctca ccttcaatac cgctgagttc gcctttgata acttttactt
     8701 tatgcccaac agtaagaatt tcgctatcaa ggctgacacc gtcagggttc aaatccatta
     8761 cgaacataaa gtcctccatt tgcttatccg gtaccactag catggaatgc gtggcaagat
     8821 ccttcatata aaaaaggggg acattataaa tgttggaaat atcgcaggct gtctgcttgg
     8881 tggaatgaac aaacaccaaa ttacggatta ctggaacttc gctacgctta cggcgatact
     8941 tcaattgtga aatgacaaaa cgcgtgggaa gataatagtc aaggtccaaa tgttcttccg
     9001 atttaagtcg gtccagagat ttccggactg tgaattcctg cttgtcacgg gtgcgggctg
     9061 caaaccaata tttctgttgt tcagtcactt aggaattttc tttcgaatga atcagctcag
     9121 ttccgggtgc gcttcgcggt ttgaacgaga cattttccca cccaaaccgt attgtacact
     9181 tttgcaatga taataagcta ttaaagaaga tattagactc ataaaagtgt ccaataaacg
     9241 ttcgtttaat aaacgtctat ttttaagaaa ataagtagag gcataaaagt taaaaaggaa
     9301 cagaacttta atatgttaaa tattagacgt acaatgctgc aattcaacat attaatataa
     9361 aacagaaatc actttgggaa tatttttatt aaacattttg ttagttcaaa aaatacggct
     9421 tatctttgcg tccattaaac gaacgtttaa aaaacacctc atcatttcca atatatcatt
     9481 ctacattcca atatcttacc ctcataaatg tattattgaa gtttcgtaaa tatacctact
     9541 gataaatggg aatttatcgc acagaacgca agtgaaataa aagcccactt ccataaccta
     9601 tggagagagt gaaagcccat ggatttctat ctaaaacaca agcattcctt tgcttttcac
     9661 ccttgcttgg tctactgttg cataaggagt tagtgacgcc taacggccat gaacaaccct
     9721 gctaatggcc atgaagcaat cgtttaacga ccataagcag ggttgttcat ggccgttagg
     9781 cgtcactaac tccaaggctt ttacagatga agtacgtagc ccgcgcctat tgcgcacaag
     9841 gtgcaaacgt attgtacagc aacttaaaag acatcagact ccactattca tagtcgggca
     9901 aactcgaaaa tgcaggaaaa ctacactgac cgatttatgt aacccacgcg cggtattata
     9961 ttaaagaaca ataagttacg acaaaactca gacgttttcg gcaggtggaa gcaaattttg
    10021 cttccacctt ttcaggttgc ttccaccgca gggtaaatgc cgatggatag ggagatgcag
    10081 gaggcgggtg gaagtgtgga agcaaagcag atgcaaattt atgtttcagc accaccactc
    10141 aagttttaaa aaagatgtag tataaagaca taatatataa taagtgttat aaatacacac
    10201 tttatacccc gttactcttg caaatgtcga aaaagtccgt acctttgcaa tgtgtttttc
    10261 atagtattag atttaaggtt aacaaaggtt ggagtacagc ggtactcctt tttttatgcc
    10321 catacgtacc gtcccggttc tccaataaaa ttttcacata aaatgcaagg caacttttta
    10381 tatccattta gtttttggct atctttgcac tgcttttggc gggcataggc acgcataaag
    10441 cagcttaact aacaataaat caataattaa aaacagaaaa ttatggcaat gcatacatgg
    10501 tttgaatgta agatccgtta cgaga
//
