LOCUS       c00005_gnlPro..        14754 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LJKEAIOP_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 06:17:34
            Original ID  :: gnl|Prokka|LJKEAIOP_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14754
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14754
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[275:4754]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      276..4754
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14754
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14754
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(276..3122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 5.3e-10,
                     bitscore: 32.5, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.8e-177, bitscore: 583.9,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRI
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFARVHATGALCVVAADLMALTVIREPGAFGTDICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3218..3598)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="GCV_H (E-value: 3e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3669..4754)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="GCV_T (E-value: 4.5e-87, bitscore: 285.1,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 5.7e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4830..5951)
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKAHSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(6010..6933)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-55, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7493..8620)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGVQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWNGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLSPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTASEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPSGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKTAHTITPLLAKMQIAGQITPDAGGYFSINSREL"
     CDS             complement(8617..9729)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGTLRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNIAVGDTAAMADLLARWHAQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9726..10742)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVLVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10752..11813
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_9"
                     /sec_met_domain="Fer4_16 (E-value: 3e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11932..12309
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12343..12894
                     /locus_tag="ctg5_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12930..13541
                     /locus_tag="ctg5_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13672..14439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_13"
                     /sec_met_domain="HAD (E-value: 1.5e-35, bitscore: 116.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYVFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDVNNVKSMTC"
ORIGIN
        1 gggcagagaa aaagctcatc tgagacgtag ctcaacggat ttccaatccg aaagagcaaa
       61 catatccaga aaacaattaa gcccaaaagc aatatgggtt gaaaaagaaa aaaggaacat
      121 ttctcccacc ccgcttttcc tcccctttca ttttgatgac ccatttgtac tcaaaataga
      181 gtgttgactt cggattggaa atccgattct tgaacataag aaaaaggctg ctccaaatga
      241 atggaacagc ctttttgaaa ggaaggatga gatttttata actctacggc cttggagaat
      301 tcctccaccg tgtcgcaggt gcagaccaga ttgcggtctc cgtacacatt atccacccgg
      361 cctacatacg gccagaattt gtgaataagg agaccggaga ccggataagc cgcttcactg
      421 cgggagtagg gatgccgcca ttcgtcggca gagaccattt ctgcggtatg gggcgagttt
      481 ttcaggacgt tgtcttcctt gtctgccgta ccgttgataa tggccgtgat ttccgcatga
      541 atgcgttcca tggcttcaat gaagcggtcc agttcttttt tgggttccga ttccgtcggc
      601 tccaccatca gggtgcccgg aacggggaag gacatggtgg ggccgtggaa gccgtagtcc
      661 atgagccttt tggcaatgtc atccaccgtg aggccggcgt catgagtgag ctgacgcgga
      721 tccagaatgc attcatgcgc caccagcccc ttgttgccgg agtagagaac cgggaagaga
      781 tgtccgagtt tcttggcaat gtagttggcg ttaaggatgg ccatttccgt ggcttccctg
      841 aggccgtccg gccccatcat ggagaggtac atccagcaga tggcggcgat ggaggcgctt
      901 ccccacgccg cagacgctac ggccccttct tcatggccca gcgtgaggtg tccgggcagg
      961 aagggtacga ggtgttccgc tacgccgatg ggcccgatgc cgggaccgcc gccgccgtgc
     1021 ggcatggcaa aggttttatg caggttcagg tggcagacgt ccgcgccaat gcagccgggg
     1081 caagtcagac ctacctgggc attcatgttg gcgccgtcca tgtacacctg gccgccattg
     1141 gcatggacga tgtcgcagag ttccttgatt gtctgttcat ataccccgtg cgtggagggg
     1201 tacgtgacca tgatgcagga aagattgtcc ttatgggctt ccgcctggga tttcaggtct
     1261 gccatgtcga tgttgcctct ttcgtcgcat ttgacgggca ccaccttgag gccggccatg
     1321 gcggaggatg cgggatttgt tccgtgggcg gaggtgggaa tgaggcagac attgcggtgg
     1381 ccttctccgg cgtgcttctg gtagcggcgg atggccagta gcccggcata ttcccctgcg
     1441 gcgcccgcgt tgggctggag ggatacggcg gcaaagccgg tgattttcgc cagacggtcg
     1501 gacaggacgg agagcatttc ccggatgcct tccgactggt ccgccggaac aaagggatgc
     1561 agggagttgg cttccggcca cgtgatggga atcatttcag aggcggcgtt cagcttcatc
     1621 gtgcaggagc ccagagggat catggcttca tttagagcca ggtcccggga ttccaggcgg
     1681 cggatgtagc gcatcatttc cgtttcggaa tgataggagt tgaaagcctt ttccgtgcag
     1741 aaaggcgtct ggcgcgtgtg gacgggatcc caggcaggag cgtcgcaatc gcaggtggcg
     1801 gatgtttccg cacctgcaag ggcagaggcc agtgccgcta tatccgcaca ggttgcggtt
     1861 tcatccagag agatggctgc gtggtcggca tccaccctgc ggatgttata cccggcttcc
     1921 agggcttttt gcaccatggc gtccgcttgt ccgggaacgg acagcagcag ggtgtcaaag
     1981 aagtttttgt tttcaatggc gatgccggct tccgtgagcg ccttgtacag gcttttggtt
     2041 ttcaagtgga tttccgtgcc gatgcgtttg aggccttcct ggccgtggta tacggcgtaa
     2101 aaggcggcaa gcacggccag gagcacctgg gcggtgcaga tgttggaggt cgccttgtcg
     2161 cggcgaatat gctgttccct cgtttgcagg gccaggcggt aggccgggcg ccccagggta
     2221 tctatggaca tgccgataag gcggccgggc atgcggcgtt tgagagcgtc cgtgcaggac
     2281 atgtaggcgg catgggggcc gccgaagccc attgggatgc cgaagcgctg cgtgtttccg
     2341 atgcagatat cggttccgaa ggcgccgggt tcccggatga cggtaagggc catgagatcc
     2401 gccgctacga cgcagagcgc gcccgtggca tgcacgcggg caaagaagtc cgtgtagtcg
     2461 cagatgcggc cgagcgtgtc cggatattgg acaagcactc cggccagatc cgcaccgatg
     2521 gatgcggggt caaaggagga gcaatctccc acgatgatgt taacgccctg gaaggcggcg
     2581 cgggtacgga tgacgctgat ggtctggggg tggcaggtgt ccgccacaaa gaaggtgttt
     2641 gctttggggc gcgcgttccg gcacatggtg acggcttctg ctgctgcggt gccttcatcc
     2701 agcagggagg cgttcgctac cggcagccct gtcagggaag agaccatggt ctggaaattc
     2761 atgagcattt ccagccgtcc ctgggcgatt tccggttgat aaggggtgta ggccgtgtac
     2821 cagccggggt tctccagtac attgcggagg atgacggagg gagtgatggt gccgtaatag
     2881 ccctggccga tgaaggtttt caggagcttg tttttccgca ggatggaacg gagttcctcc
     2941 agggcttccg tttccgattt ggctgcgggc aggtccagcg gggcctttat gcggatatct
     3001 gcggggacga tgtccgcaat gagttcgtca agcgtccggt agccgaggct gtcaagcatt
     3061 tcccggcgtt cttccccctg ggggccgatg tgccggctgg caaaatctga gtgggtattc
     3121 atgtggtatc tctggctggt aatagcgtcc ggccgcggaa cgggccaaac aaaatgcccc
     3181 gggatggaat caccggggcg ggggagggaa gaatggttca ggagcagtat tcctcgtaat
     3241 ccgtggcgtt catcatatct tccgtttccg tgggaacgtc caggcggatt ttgtacagcc
     3301 agcctgcgcc gtaggggtcg gagttaatga gggacggatc attggaaagc tcttcgttca
     3361 cttccaggat ttctcctgaa acgggggtgt acacgtcgct ggcggctttg acagattcca
     3421 cgacagcgac agggtcgcca gctgcgacgg tggcgcctac ttcgggaagg tctacaaaga
     3481 cgacatcgga gagttcggcc tgggcatggt cggaaatgcc gatggtgccg atgtccccgt
     3541 caatttcaat ccattcgtga tctttggaat acagcagatt ttctggtacg tcgtgcataa
     3601 gatgtaattg tttgaagtga gagtgtagta aaataaggtg tttgtcagtt tatttttgcg
     3661 ccgtagtgtc agcctttttt ataaaagggt ttttttacga ccacggctgg gaatttcctt
     3721 ccccttacgt caatttccag ctccgtgccg accttggcat gggcggcagg caggtaggcc
     3781 agggcaatgc ccttcatcag cgaaggagag agcacgccgc tggtaagttc tccgatggct
     3841 tctccgccag ggacgtgcac ggcatagtgg gcgcggggag gagctccctt gccggtgtat
     3901 tcaatagcgg ccagccgacg gctgaggccg ttggcttttt gttcccggag aatatcggaa
     3961 ccgatgaagt ccgtatccag cgcgcagaag aatccgagcc ctgcttccag aggcgttttg
     4021 tccggagaga ggtcggagcc gttcagagga tagcacattt ccagacgcag gctgtcgcgg
     4081 gcgcccaggc cgcagggttt ggctcctgct ccaagaaagg cttcaaacca tttgacgcct
     4141 tccttagccg ggcagaagaa ttcaaaacca tcttccccgg tatagccggt gcggcagata
     4201 atgagatccg tcccttccgc cgtgatgcgg gagattccat tgcggggggg aagttccacg
     4261 ccggggatga cgcgggagaa tacttctccg cattcgggac cttgaacagc cagccccacg
     4321 tattcgtcgg agtggttttc cagggttacg cctgcaggtt gatgggcgga aagccatgcg
     4381 aagtcttcat caatcttgga ggcgttcacc actacgaaga aggtttccgg ttccatccgg
     4441 tacagaatga ggtcgtcaat gactccggcc ctgtcattga gcatgacgga gtattgcccc
     4501 tgccctacat tcagtttgtt aatgtcattg gtcagcatgg agttcagcca tgccgcagcg
     4561 gaaccgccgg ctaccgtgaa ctgccccatg tgggagatgt caaagatgcc gcaggtttcg
     4621 cgcactgctt tgtgttcgtc cagaatgccg gtgtactgca ccggcatatt ccagccggcg
     4681 aaaggaacca ttctggctcc cagttcaacg tgtttagctg ccaggggggt ggatttgacg
     4741 tctgtatcag tcatgaggcg atgtgaaggt tatgagcaat ctgcccctta tatcagtaaa
     4801 agtcaatgga attccggtaa cgcttccgtc tagacattga agcggaattc gatgacgtcc
     4861 ccgtctttga cgacatattc ttttccttcg atgcgcagct tgccgtgttc cctcgctccg
     4921 gccttgccgc cgcaggaaac caagtcgtcg tagtgcacta cctccgcggc gataaaaccg
     4981 cgttcaaagt ccgtgtggat gacgccggcc gcctggggtg cttttgcccc ggccggaatg
     5041 gtccaggccc gcgtttcctt gattcccgtg gtgaggtagg tgcgcaggcc cagaaggtgg
     5101 tacacggcgc ggataaggtc ggaaacgccg gagtccttca cacccaggga ttccaggaat
     5161 tcgcgggatt cttcctccga gacgtcgatg agttcctctt caatccgggc ggagatgaca
     5221 atggcttccg cgttatggtg ttccgctacg tattttttca cctgggagac gtagggatgg
     5281 gcgtccgggt tggagatggc gtccgccagt tcgtcttcat tgacattgca ggcgaaaatg
     5341 ctttttttat ccgaaagcag ctggaaggaa tggagcagct tgcgttcgtc gtcgtccagc
     5401 tgcggttcaa gggtgagggc gggattgcct tcgttcaggt ggggcaggag tttggtgatg
     5461 agggccactt cggccttggc ttccttgtcg ccgctgtgtg ccttgcgttc gcgggaagag
     5521 agtctctttt ccatggtggc gatatccgcc agaatgagtt ccgagttgat gatgtcaatg
     5581 tcgcgcagag gatccacgga accgagttca tggataatat catcattgtc aaagcagcgg
     5641 actacctgca cgatggcgtc cacttcacgg atgttcgcca gaaactggtt gcccaggccg
     5701 gctccttccg aggctccctt gaccagaccg gcaatatcca cgaattcaat aagcgtgggg
     5761 atgatttttt cagaaccgga catgtcggaa agaacctgca ggcggggatc cgggactgtt
     5821 accataccca cgttcgggtc aatggtgcag aagggatagt tggccgcctg ggccttgcgc
     5881 gtccgggtga ccgcattgaa tagagtggat ttgccgacgt tggggagacc tacaatacct
     5941 gcctgtaaca taggcaggac tgatagcggg tcacgccgtg aaagtcaaat accaattgcc
     6001 gacgggcatt tatgcggcgg atcccagagc ccatctgatc aggttttccg attccgtcca
     6061 gatacgggac ggatggcagc cgaggacgac gacgatgaca tggcgcccgt tgacgccggc
     6121 tgaggaaacc aggcagcgtc cggcggcgtt cgtgtatccg gttttcatcc cggtaaccca
     6181 ggggttctgg gtgagcagct tgttggtgtt tctcagcaga agcgttctgc cgttggcgcg
     6241 ggtaaaggca tattggcgtt tgcagataat attgcgcagt tccgggttgc ggtacacgta
     6301 ataggcgcag cgggccatgt caatggccgt ggaatattga tccgccggga ggccgttggg
     6361 attggcgaag cgtgagttgt acatgcccat ctgccgggct ttggcattca tcaactgggc
     6421 gaaacgggga acggaacccg ccgtatcgcg ggccagagcc agggctacgt cgttgaaact
     6481 gcggatcatc atggcattga gcagttcgcg gcgtgaatag acttcccccg cccggaatcc
     6541 cagtttggtg gggtccgcct tggtatcgga aggctggatg accacttttt tgtccaggct
     6601 gccgtgttcc atcacgacca tggccgtcac gagtttctgc gtgctggcta cctggcggtg
     6661 ctggaggccg ttgtgggaaa agagcacttt gccggtaagg gcgtccatga cgcaggcgct
     6721 ggcgcagcgg ggcgtgcgtg gggcgcttga ggggatggct acgggacgtg tggggaaatt
     6781 ggccggtcgg gggagggcat gggaaaccgg ctgggagagt tgtgggggaa cgggcgttgc
     6841 aagggggatg tagtcacttg aatccccgta cgattggcag cttgtggagc tcaggcaaag
     6901 ggagaatcct gcaagaaggg cgaataaacg catgtcttgt tgctacagta agaagtttcg
     6961 ttcatcaagc ccaaactccg catttgaaag agagccggac gaaaaaggcc gcggatcgga
     7021 caatccgcgg ccttttttct ctattaacta cctatggaac caaaaaccac cctaaacgga
     7081 ttttgaattg ctttttccat ccgtcggaca gatcttgtgg aggatgagac tactggaagg
     7141 agggatgcgt tcaaaatatg ttcgtcaaca gttcttttaa gagatgttgc cgtatgagcc
     7201 cgatcctgcg tccagtaaat attgcagaga ttttttccga acatattttg tttttcgcgg
     7261 gcatgtaaat cttgccgcag gcatttaaaa tgccggggat gtcctgccga tatatttaat
     7321 ttttggaata taattattga aggaaaggat ttggcgacta ttttgagacg tttttttgca
     7381 tccggatgga aaggttttta tacgggagat ggacggcgct cccttccggt tccatggtca
     7441 gggagaggag gcccggatct ggcgttttcc ccggcggcaa agcggaatct gcctaaagtt
     7501 ccctgctgtt aatggagaaa taccctccgg cgtccggagt aatttgccct gcaatttgca
     7561 ttttggccaa aagcggggtg atggtatgcg ccgtttttcc cagagaggtg cagagggtgt
     7621 caatagtatt gaaacccagt ctgatggcgt ggagaatctc cttttcttcc aaagtgggaa
     7681 gcggtggggt tgaggctccg gaagggggac atggcgagaa gagaggcagt ccctgttccg
     7741 gaacggccca gttcatgtcc tgcagaatat cggaggctcc ggtagccagg atggctccgt
     7801 cccggatgag ggcatggcat ccgtcggaag aatgccggtc aaccggtccg ggaatgcaga
     7861 aaacctctcg gccctgttcg gacgccgttc gggccgtgat cagggccccg ctgcgtccgg
     7921 acgcctccac caccagtgtg gcgcggctcc agccgctcac gatgcggttg cgcatgggaa
     7981 aagtggtgcg ggagggggac aggtccattg ggaactcgga gactaccgct ccatgcccgt
     8041 ccgcaatgcg ctgcgccaag tttctgtttt cccgaggata cagtttgttg agacctgccc
     8101 cgataacggc gatggtgcgc ccctccgcgt ccatggcccc ggtatgggct tccgtgtcca
     8161 cgccgcgcgc cagtccggaa atgacggtga ctccggcttc cgccaggtca tgggagatgt
     8221 ttctggcgca aagcctgccg taatgggtgg ccatccgtga gccgacgacg gcaatggagc
     8281 gttcggcatc cgttccgttc cagtttcccc aggagtagag gacaatgggc gggtctggga
     8341 gagcacgcag ggaggatggg taggagtcgt caaaaaccgt ggttactgcg gcccccgcgt
     8401 tatccgccag ttccagttcc ctgtacgggt tgacgatgct ccgccaagag gaaatgcggc
     8461 aagccagctg cacccccacg ccgggaattt ccatcaacag ggaggaaggg gattccagaa
     8521 tcagttccgg agaggcgaat acctgcagga gacgcatgat tctgacaggg cccaggcccg
     8581 gtatcaggtt cagggctatg gctgcttccc ggggtgtcat gaataagggg tcagttcctg
     8641 gtaaacgtcc agatgggctt gaatcatatc ctgcatattg taaggggaag gaatttgccg
     8701 gggcaggggg gggggctggg catgccagcg ggccagcagg tccgccatgg cggcggtatc
     8761 tcctacggcg atgttccctt caggaaggaa ggcgtccagc tgttccttga ctccgccgtg
     8821 ggcgtatccg gccacgggtt tgcccagggc gagcgcctcc agggttgatt tgccgaaagc
     8881 ttccgggctt ttggtcaggg agagggtgac ggaacatgtg gaaaggattt ccctcagatc
     8941 ctggcgatgt cctgtccagg tgaaggactg ggagacgccg gaacgttcta ttgcccgcag
     9001 gacctcgttt ttatattctt cttttccctt ctttgcttct cctacaatga cggcgtgggc
     9061 cgggatcccc tgttccagaa gctgcctgac gaccggaatc agatccagat gccctttcag
     9121 gcgcgtgatg cggcccggca ggcacagggt gaatttcccc ttcagttcag gataggacat
     9181 gaaccagccc gtgagccatt cccgggaggg ggagtaggcc ggatgatatt gatccgggga
     9241 aatagcattg ggtatgattc tgatatggtc cggaggggtg gacggataat ggtcaaggat
     9301 gtagtccctg atgcagttgg agacggcgat caccctctct ccccggctca tgatggcgga
     9361 gtaccggttg acggagtaga agccgtgaac gctggtgacg aggccgggac ggtcttcggg
     9421 cgggagcttt ttccatgcca ggtagcctgc ccacgcagga acgcgggaat ggagatgcag
     9481 gatatccggc ctgacggcct gaagcagggc gcggagggtc ccgatgcgga agagagtgga
     9541 gatgcttttt ttgcctatcg gcatcaggat gtggcgggag ccttcctttt ccagacgggg
     9601 caccaggcgt ccgcctccgg aaacgacgat attttccacg ccccgggaag aaaggccgct
     9661 gcccagttcc ataacgactt gttccacgcc tccggattcc atggagggga cgagatgtac
     9721 tattttcata aggcgcggag ctgagggaaa aatctggaga ggatgtagtc tgctgcacgg
     9781 tccgcttcca gaagcgggga accgggagcc gtcaggcgga agttctgttt tttccagtca
     9841 ctgtatccag taaccatgcc ttccttttcc agtgtctcca ggccggacag gatgcgggat
     9901 ttgcggctgc cgtgtcggcg cggtacggaa aggatgccta caggcgcgcc ggagccaaga
     9961 gcctcatata ccatggagac gctgtcctgg ctgacccagg cggcggaggc gtgcgccaga
    10021 tgccgggcta cccaccccgg ccgggtttcc tccacgagaa cgacggttag ttccggaacg
    10081 gccgtccgga ttttttccgc aaagccgtcc ggcgtccggc gcgaggtggt tagaacaagg
    10141 tgtccggggg tgtggatgct gatggacgcg agctggttga gcatgctttc gtcatcccag
    10201 tcaaaatctt tgctgggccc tcctatgaga atcagtgtgg tatcctttgg tacggaggga
    10261 tccggcctca tggggtggag agctccctgg gtggggaaga tatccgtatc cgtgtaatcg
    10321 cggccggaat ccaggtcatg gcggggaata aggcagaggt cgaaaaagga acagggaagc
    10381 gtaggcttca tgcagaggac ggcccgggtt ttgaaatggt gccgcgcgca gatgagcggg
    10441 atatgcgttg catgtccggc ggaaatgaac agatccggcc gtggaatgtc gctgcctgtg
    10501 acgaccttcc ggattttccc caaaagggaa agcccctgca ggtctaccgt ttccacggtt
    10561 ccccccgctt tggagatcag agcctgcgcc agccccaggg actggttgag gtggccctgt
    10621 ttcccatcgc tcagaatccg gatgttcata tatgcggcat tatgaagcgg cggcggggtg
    10681 caggcaatcc aatttccacc ggacagaaga aaattcttgg tgggaggcat gctcttgttc
    10741 atgattccgg cgtgctgact ccggattcct ctgttattaa agattccttg tgcgccgtgt
    10801 cccggcagct tggtttttcc ggctgccggg tggcccgtgc ggaaaaaagc ccgcatgcgg
    10861 aaaaattgtt tcaatggctg gagcgcggat ggcacgccgg gatggagtgg atggcgcgtt
    10921 ccccggagcg gcgcacggat cctgcggaag tgcttcccgg atgccgttcc gtcatttgcc
    10981 tgtcctatga ttatgacagc cccggtaggc gcccggaggg ggagggtagc atttgccttt
    11041 acgcccatgg aaaggattac cacggaattc tggaggaaaa actggcggat ttgcaggagc
    11101 tgctttccat ttacggcggg aagcagaggg ggtatgtgga ctccggccct gttatggaac
    11161 gagaccatgc ggaggcctgc ggcctgggct ggcgcgggaa aagcggtttg atcgtgcgca
    11221 ggaaaggggg ctcccgcttt tttatcgcta ccctgctgac tacgctggaa ctggaaccgg
    11281 acgctccggt ttcaaacgga tgcggcagtt gccgccgttg tgcggccctg tgtccgacgg
    11341 gcgcaattat ggaaaacggt caggttgatg ccggacgctg cctttcctac tggacgattg
    11401 aacaccgggg ggctattccg gaagaaatcc gtcccctgat aggcacgcgc ctgtacgggt
    11461 gcgatacctg cgtgacggtc tgtccctgga atggtaagcc tttgccggac gttgacgaac
    11521 ggttccgcat gtcccgtctg ctggcttcca ttcccctgcg tggtcttctt tccctggatg
    11581 ccggcggttt tgcggccctg ttccggaatt ccccgttgaa aaggctcaag agggaagggc
    11641 tgctgcgtaa cggctgcgtt gtgctgggga atgcggggac tccggatgac attgattttc
    11701 tgaaggcgct ttacggggag tctcctctgg tggaggaaca cgcttcctgg gctgtggagc
    11761 gcatcctccg ccgccacggg cggcatgcat cttcaagcgg tgcaagagat taaaaataga
    11821 aaaaatgatg ttttggtctt gtcaaaacct caatttatgg tatccatctt gccccaagca
    11881 atagctctgc gcgaggcaga gaaaaataac agctagcaaa tccaatccat tatggcacgc
    11941 cttttcggta cagaaatacc caacgagaag cgcatcgagg cttcccttcc gtatatttac
    12001 ggaattggtc gctcgacttc taagagaatc ctggaacaag caggcatcaa tcccgacatc
    12061 cgcacgggac agcttaccga cgaacagctc acgaagattg ttcaagtaat caccaccgac
    12121 ggcattttga ttgaaggtga ccttcgtcgt gaaaagcaat ccattctcaa gcgtctgacc
    12181 tccatcaact gctatcgtgg tcagcgccac cgccgcggcc ttccggtacg cggtcagcgt
    12241 acccgcacga atgcccgtac ccgtaaaggc aagaagaaga ccgttggcgc gcaggccaag
    12301 aagaagtaat ccgccaacct gaatttttaa tatagcttta ctatggctag cgaagaaatc
    12361 accaacgaaa ccgccgaaca gcctgtggaa gcggcagctt ccgctcccgt cgctgaaact
    12421 ccggccgccg ctgtttccgc tcctgaagaa atcaagaagc ccgaaccccg caaggatatc
    12481 tttgcggaac ttggtctggg cggcgatgat gacaagccca aaatcctgaa ggccaagggc
    12541 agcaaaaacg tttccacggg cgtggttcac gtttcctcca cgttcaataa caccgtcgta
    12601 actgtgactg accagcgcgg caatgtcatc ggctggtcct ccgccggcaa gatgggcttt
    12661 aagggttccc gcaagagcac ggcctatgcc gggcaggtgg tgtgccagga cgcctgccgc
    12721 caggccatgg gtcacggctt gcgtgaagtg gaagtgcgcg taaaggggcc cggttccggt
    12781 cgtgaatccg ccgtacgtgc cgtgcagacg atcggtattg aaatcacctc catcaaggac
    12841 gtgaccccca tcccccacaa cggctgccgt cctccgaagg cccgccgcgt ctaattgaga
    12901 atcttttacc tatatagatc taatatatca tggctcgtta taccggtccc cgcgataaag
    12961 tgtcccgccg ttttggcgtt gcccttttcg gttccaccaa ggctcttgaa aagcgcccct
    13021 tccctcccgg ccagcatggc atgcgcgccg gccgcaagaa gaaatccgac tatggcgtga
    13081 tgcttgctga aaaacaaaaa ctgcgtttcc agtacggtgt gcttgaaggc cagttccgca
    13141 agtattatgc agaagccgcc cgccgccgcg gcattaccgg cgatattctg cttcagctcc
    13201 ttgagcttcg tctggacaat gttgtgtacc gcctcggctt cagcaatacc cgtgccggcg
    13261 cccgtcagct tgtttcccac ggtcacatca ccgtgaacgg caagaagacg aatatcgcgt
    13321 cctactcctg ccgtccgggc gacgtcattg ccgtaggcgg caaggcttct tcccagcagc
    13381 tggttacccg tttccttgac ctgactcagg ctactgtggt tcctgactgg ctggaatgcg
    13441 accgtgacaa gctcacgggc aagattgccc gcgtgccttc caaggaagag attgctccca
    13501 tcgtcaacga gcagctcatc gtggaatttt actcccgtta atcttatttc cttctggatt
    13561 tgcttcaaaa ccccggttgc ctttcggcgg ccggggtttt gggcattcag gaggaggggc
    13621 atggaagagt tgggtgttga gagttaaggg aagcgggtat aggatgaaag catgacggac
    13681 gattggaaaa aaagaggcgc agcgctgttt gatatggacg gcacgctcct tccctgggat
    13741 acgcaatatg ttttttcctg ttttgtggtg aggcgccacc cttggaggcg cttgctgatt
    13801 tttcttttcc tggcctgtat tccgctctat attttgagaa tatgggatga gaaccggatg
    13861 aagagggctt atctcatgta tttgtggggg cttcccgctg aaacggtgcg ggaatatgga
    13921 cggaagtttg ccgagatggc gcaggaatgg atttatccgg agctgaagga gcggctggca
    13981 gggtatcgga agaagggtta tttgtgcctc atggtttccg cttctccatc attttacgtg
    14041 aagcctctgg gcgaactgct gggatttgac gaagttctgg ggacggatgt gcttctggag
    14101 gaacgcatgc cggcaatgcc ggaactgccg aacggtaata ataagggggc ggtgaaggtg
    14161 gagcgtctgc gggagcggaa tgtactgccg gaacatggtg ttctggaaaa cgccgttgcc
    14221 tacagcgaca gtgccgcgga tctgcccatg ctgctttcct gcaggcggag ggttctggtg
    14281 aatccttctc ctgccctgaa agaagacagg cttctggatg gtgcggagtg tctgtatccg
    14341 gccaggcctt ggaagggaag gtttggcaag atatggagaa ttggattttt tgtcatgggg
    14401 ctggtggatg taaataatgt gaaatcaatg acttgctgat ttatcaagag aaaattcttt
    14461 acttttgtga cgaaaatgtt tcacttttct taacaagggg ggaaaaagca tttttctttc
    14521 catgttagca aatcaacaat taatacccta accaagtaat agtcatgcaa accaagaaca
    14581 tcatcagtgt tgcggcagtt gtggcatcct ttgccggagc tgctcttgcg ggtactcccg
    14641 tcaagattgt tgctccgact ccggttcccg ctcctgtggc gacttccagc ccgctgtccg
    14701 gcgatattta cgccggctac gcttccaatt acacctgccg cggcattgtg gctt
//
