LOCUS       c00018_gnlPro..        24857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DDLGFDJN_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 11:08:13
            Original ID  :: gnl|Prokka|DDLGFDJN_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 95548
            Orig. end    :: 120405
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24857
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[105548:110405]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             781..1890
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_90"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 2.3e-08,
                     bitscore: 28.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMKRELHTFIIGSVLFFTACGDKQESEQKSGYRIQGDTVYIADP
                     LLLEKIKVSVSELKPYSKKVITSGVVRPIPPRYAYVAPPFAGRVTKSYVRIGQSVRQGT
                     PLFEISSPDFTSAQKEYFQALSSRELAKKDLKRKEDLIRNGVSSQRELEEAQNALLIAD
                     KEFENASAALRVYQVDNPAEMILGQPMIVRSPIPGEVIKDNIVTGQYLKDDTEPIAIVA
                     DLSKVWIAAQVKEKDIRFINEGSSLDIEISALPGTVIKGNVYHVEEEVDEETRSIQVLS
                     VCDNLNGHLKLGMYTTVHFLSVPVGQIQIPEKTLLQGEKDSYVFVQIAPLVFVRTSVTV
                     ETTENGIAVISEGLRPGDKIISEGGYYLK"
     CDS             1897..5004
                     /locus_tag="ctg18_91"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVFLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITRFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSITTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPAFYYLVENNVLNKKKNDEKEYTI"
     CDS             4982..6232
                     /locus_tag="ctg18_92"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFAQMPEIKLGQSISFEEYLNRV
                     AKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLEAVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALESACGIWDICF"
     CDS             6568..7335
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_93"
                     /sec_met_domain="Acetyltransf_1 (E-value: 1.3e-06,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVGVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             7714..9483
                     /locus_tag="ctg18_94"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMTMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKKTGM
                     TPYEFKKTQESLG"
     CDS             9554..9916
                     /locus_tag="ctg18_95"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             10001..11233
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_96"
                     /sec_met_domain="HBT (E-value: 7.9e-16, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             11230..12342
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_97"
                     /sec_met_domain="Chorismate_bind (E-value: 1.2e-56,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             12362..14029
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_98"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.2e-07, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             14033..14857
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_99"
                     /sec_met_domain="ECH_1 (E-value: 7.7e-81, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             14861..15886
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_100"
                     /sec_met_domain="MR_MLE_C (E-value: 1.6e-28, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             15886..16989
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.5e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_101"
                     /sec_met_domain="AMP-binding (E-value: 5.4e-16, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFLN
                     EWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYIG
                     AMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQTE
                     ILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVEL
                     FLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIERL
                     LQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNHI
                     PQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(16963..17532)
                     /locus_tag="ctg18_102"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             17757..18680
                     /locus_tag="ctg18_103"
                     /transl_table=11
                     /translation="MENMNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRR
                     SMYNQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVV
                     WLNSGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVN
                     AYEDDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWK
                     DGKLIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAA
                     LKWRTEEAVQQADDTFTKKKIIVDLY"
     CDS             18930..22229
                     /locus_tag="ctg18_104"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSGKILDILDDIFKGTDITYTVVDKQIILSTNKMQL
                     VQQEGQIQIKGVVKDAGGDPLIGVNVKVKDSTVGTITDINGNFTLQTRKGDILEISYVG
                     YATKTVKVQNAQVLNIVLTEDTEVLNEVVVTALGIKKEAKSLSYNVQQVSNAEITRIAD
                     ANFVNNLNGKVAGVTINSSSAGVGGSSRVVMRGTKSLNGNNNALYVVDGIPMSDMSAAS
                     TQPTDSYEGAGQSGDPISGLNPEDIESISVLSGPSAAALYGSAAANGVVMITTKKGREG
                     RTSVSISNNTTFSAPLVLPEFQNTYGQTEVGSYYSWGSKLNTPSSYDPKDFFQTGVNVT
                     NAASLSTGTDKNQTYLSLGTTNAKGIIHNNDYERYNVTVRNVAKMLKDKLTLDLSFMLS
                     SVKEQNMTSQGLYYNPLVPLYLFPAGDDFSKVQAYQRYDSERNLLTQYWPYSTSLALQN
                     PYWITEHIKIPNHKNRYMATASAKYEFADWINVTARAKMDRNNERRERMYDAGTNTLFA
                     SKYGYYSKSNIENQQIYGELLLNINKYFVDNTLNVTANVGGNFENNDYQSDYFGGKLKS
                     VANLFTFGNVDTSEKNLANQYGYHLKKRAIFGSAQIGYKSMAYLDVTARNDWSSTFKGT
                     NTGSFFYPSIGLSGIITDIFRCSTDIMPYMKVRISYSEVGNSPDVFLAIPTYALVDGVP
                     VTQSRRPNPNLKPERTKSWEAGFNFVFFKNRLRLDGSIYQSRTYNQFFERTLSSTTGYK
                     SEVVNGGRVDNKGIELSLRFEDKWGNFGWSSYLTYSLNRNKVVELLRNYEDPYTHELTS
                     LDRIDMGGTSMYKMILTEGGSIGDIYVNTLRTDEHGAIYVHPSDQVVVTQPDEFVKAGN
                     SAPKYNLGWGNTFSYKGLSLGFLFTARVGGVVVSQTQATMDAYGSSKATAIARDNGGAI
                     VNGRPIGAEDYYTKIGGAGAQGGIGSMYTYSATNVRLAELSLGYDIPINKYVDWIKGLN
                     VSFIGKNLFFLYRKAPFDPELTASTGTYFQGIDMFMSPSLRNLGFSVKVNF"
     CDS             22254..23849
                     /locus_tag="ctg18_105"
                     /transl_table=11
                     /translation="MILNKILSWNKLSILGISLMLLNNISCIDYEDNVNPNEVTEEMME
                     VDNLKTGAFFSQMLRRVVIINDGDKLDSDYQIAQNLSHDLYSGYIAATLGSTNHNGQYN
                     FQEQWVNATFDYAYTGIMAPWQSIHKIATEQELPEVDALATIVKVEGMHRIADTFGPIP
                     YVNYGSSSLYDALDLVYNKFFEELDNAIEVLSNYVNGNVDAKLMSDYDCVYGGDVEKWV
                     KFANTLRLRLAIRVSYANPTLAEAQAKKSMENMFGFIESKAERAELSHNSLEYHHPLHE
                     IAYNFNSGDCRPGATIVAYLNGLNDSRISSYFTAADDGEYHGVRIGITTSNMSNYQGNK
                     ISNLNINRASTPVVWMTAAESFFLRAEGALRGWDMGGTAKSFYEQGVRMSFEENNAAGV
                     DDYLADHTSTPGAFADNVGSDNYTFSSRVTPAWDDNAGFEAQLERIITQKWIANYPDGP
                     EGWSEYRRTGYPEVIPVVRNSSNGTIDTQLQVRRLPYTRDEKINNASGVASGISALGGK
                     DTGGAKLWWDKKSR"
     CDS             23892..24833
                     /locus_tag="ctg18_106"
                     /transl_table=11
                     /translation="MKTKITGLLTFLIGTFFFYSCDTDVEALEIQKLKTYDEQYFENLR
                     AFKKSDHEISYAYYEAWSPIEGVTGYKDPASWGERMVGLPDSIDIVNLWMGIPTAETHP
                     IAYADMQYCQRKLGTRFVMHADASHYRHQFTVDGVDYDLSQNKDDEAMAAYAKWIVNQV
                     LEPGLDGVDVDWEGWSGSDLVRLIKELGKYFGPEGEQPDKLLIVDYFSGTPPTDIIPYC
                     DYIVQQAYSDQVGFLTQPSNFPPEKMIYCESFGVFYADGGQLMNYARWEPSKGRKGGCG
                     VFYLGRNYYSSSGIPYNEFREAIQIMNPAVNE"
ORIGIN
        1 tttaatgtac cttttgcagg aaatgcggct tcaagtgcag actacgctac agcttttact
       61 actccttttg gtggaactgg taatacaggt cctgggacat atccttacgg agcaaacaaa
      121 gatatgcttg cccggaaaca actaaaagga acaacttata cattttattc ggacggattt
      181 ttcgacagac gtccgataaa agaggcttcg aatggaaact atggcgtatc attaggaaat
      241 agtaatgttg cttatcaggg agtattgtat tttaatcccg attccggaac gaatgcatct
      301 gtcttttttc cgtcagccgg tcgtctgaat aacacaagtg gtgctttgga aagtaggggt
      361 agtaccggat actattggtc ggcaagtgta ggtcctcctt atatgagatc ggaattgcag
      421 aatccacctt atgacaggag aatacgttat ggagcctggt cgcttgagtc tgcatataat
      481 tctcataatt tcagattgtc atatcaaggt tttgctcaaa gtatacgttg tgtgaaagaa
      541 taagaacttt tcggcttacg ataaaaatac cggaatatca tccgttgagg ggttggcttt
      601 ttagtcaacc ccttatttgt gcgtactctc taacaacaaa actgctgttt taagaagaaa
      661 tctttattta ctctaataag attctaatag gattctaact attctctaac aggctctccg
      721 aagggagccg tctatctttg tgcccggaaa tccggttact aacttaactt atgtttaatt
      781 atgatgatga agagagagtt acacacattt attattggca gtgtgttgtt ttttaccgca
      841 tgcggggata aacaggaatc agagcaaaaa agtggctatc gtatacaagg tgacacggtc
      901 tatattgcag atcctctttt acttgaaaag atcaaagtat cagtgtctga actgaaaccc
      961 tattccaaga aggtgataac gtccggtgtg gtgcgtccca ttcctccccg ttatgcttat
     1021 gttgctcctc catttgcagg gagagtcaca aaatcttatg tgcgtatcgg acagtcggta
     1081 cgtcagggaa cacctttatt tgaaatcagt tcccccgact ttacttctgc acaaaaggaa
     1141 tactttcagg cactttcgtc cagggaactt gctaaaaaag atttgaaacg caaagaagat
     1201 ctgataagga atggtgtcag ttcgcaaaga gaactggaag aagcccagaa tgctttattg
     1261 atagcagata aggagtttga aaacgcctct gccgcattgc gggtatatca ggtggacaat
     1321 ccggcggaaa tgatattggg gcaaccgatg attgttcgtt ctcctattcc cggggaagtg
     1381 ataaaggata acatcgtaac agggcaatat ctgaaagatg ataccgaacc gatagctatt
     1441 gttgccgacc tgtctaaggt atggattgcg gctcaggtaa aggagaaaga tatccggttt
     1501 ataaatgaag gcagtagtct ggatattgaa atttcggcat tgcccggtac ggttattaaa
     1561 ggcaatgtgt atcatgtaga ggaggaggta gacgaggaaa cccggtccat tcaggtactt
     1621 tcggtctgtg ataatttgaa cggacatctg aagctgggga tgtacactac tgtccacttt
     1681 ctgagtgttc cggtcggaca aattcaaatc ccggagaaaa cgttactaca gggcgaaaag
     1741 gatagctatg tatttgtgca gattgctccg ttggttttcg tacggacgtc ggtgacagtg
     1801 gagacaacag aaaacggaat agcggtgatc agcgaaggat tgcgtcccgg agataagata
     1861 atcagtgaag gaggatatta tttaaagtaa gaaattatga agaaggaatt aatgctttca
     1921 attatacaaa aaagatgggt aatgctttgc ctgtttgtga tgatgtgtat ctttggatat
     1981 tactcatgga aacagctttc gatagaagca tatccggata ttgcagatgt cacttcccag
     2041 gtggtcactc aagttcccgg actggctgcg gaggaagtgg aacagcagat aaccattcct
     2101 ttggaacgcg ctattaatgg gctgcccggt atgcacgtca tgcggagtaa gagtacattc
     2161 gggctgtcaa tgattaccat tgtctttaag gacgggacag aggactactg gagccgccag
     2221 cgcgtacagg aaagattgaa tgaagtagaa ctgccttatg gagctgttcc gggacttgat
     2281 ccgctgacat ctcccgtagg agaagtgtac cgttatatca tagaaagtga ccagcactca
     2341 ttacgcgaat taaccgacct tcagaactgg gtaattattc cccgtatcaa ggaagtgtcg
     2401 ggagtggctg atgtaaccaa tttcggtggg atcactactc agttccaggt tgaagtagat
     2461 ccgtccaaac tggaacaata taatttatct ctcagccagg ttgttgaagc cattgagaat
     2521 aacaatgcca atgtgggggg aagcgtgttg aatcgtggtg acttgggtta tgtggtacgg
     2581 ggaattggat taatcggaaa tttggacgat ttgggacata ttgtagtgag tactacttcc
     2641 ggagttcctg tctttctgaa tgatataggt tctttgaagt atggaaatct tgaaagaaag
     2701 ggagtgctgg gatatacgga ccgtacccgc aactactctg agagtctgga aggaatcgta
     2761 ctccttctga aacatgagaa tccgtctaaa gtactggaag atattcatgt ggcagttgat
     2821 gagttaaata atgagacatt gccggaagga gtgaggatac atacttttct ggatcgtacc
     2881 aacttggtgg atactacttt gagtaccgta tcccatacct tgctgatggg tatggctttg
     2941 gtgtttcttg tgcttattct gtttctaggc aactggcgtg gtgcattatt ggtatctata
     3001 acgattcctg tgtcattgct tatcgctttt attcttatgc atctgacgga tattccggct
     3061 aaccttctgt cgcttggtgc tattgatttc ggtattattg tggacggtgc tatcgttatg
     3121 ctggaaacga tccttaagaa acgtgaggat aatcccaaac aatatctcga agaaaaaagc
     3181 atggcgcaac gcgccaaaga agtgggtcgg cctattcttt tctcaaccat tgtcattatt
     3241 acggcatacc ttccgctgtt tgcctttgaa cgtgttgaac gcaaactttt tactccaatg
     3301 gcatttacga tgagctatgc aatgattgga gcactgttgg ttgcgctctt attgattccg
     3361 ggacttgcct atgcaatcta tcgtaaacca cataaaatat ataagaataa atggctggac
     3421 agactaaagg ataaatacat tcgtaccatt acaagatttc tggaagctcc cttaaaagcc
     3481 atcattccat caggactgat tctgacagcg gggatcgtgt tgagtgttgt cgtaggaaaa
     3541 gacttccttc cggagctaga tgaaggttcg atatggttac aggttaatct gccacccgga
     3601 atttccgtag aaaagtcacg ggagttatcc gatactttgc gtgcccgtac gatgaagtat
     3661 tccgaagtaa cttatattat ggtacaggcg ggaaggaatg acgacggaac tgatccgttc
     3721 accccttcac attttgaagt gtccatcggt attaagcctt atgatgaatg gccgaaagga
     3781 aaaactaaaa aggatttgat tcatgaactg gaagaagaat ataagttact tcccggtttt
     3841 aaagtaggat ttagccaacc tatgatagac ggggtgatgg ataagatagc cggggcccat
     3901 agtgaactgg tggtgaaagt atatggcgaa gattttcgtg aaacacgtcg tattgccgaa
     3961 gaaataacca gggcattagg aactgtgcga ggggctgttg atctggatat tgatcaggaa
     4021 ccacccttgc cacagttaca gatcagtatg aatcgtgatg ccatagcccg ttacggatta
     4081 aatgtatccg atgtagcgga tctgattgaa gtggctgtcg gaggtaaagc tatcgcacaa
     4141 ctttatcagg gtgaccgcca gtatggcatc acctgtaagt ataaagagga agcgcggaat
     4201 actccggaga aaatagccgg acttatgttg acttcttcca ccggtgcaaa gatacctctt
     4261 tctcaggttg ccgatgtcag attgagtgtc ggcgaaagta cgattaccag ggaaatgaac
     4321 agacgccatt tgacggtaaa gctgaatttg cgcggtcgtg acctgacatc ttttctgaat
     4381 gaagcccaga atacgatcaa tgagaaagta cattatgaca agaataaata taccatcaaa
     4441 tggggagggg ccttcgaaaa tcaaaaacgg gcttatacac gtcttgctgt cattataccg
     4501 ctgacactga cagggatgtt tatactgctt tatgtcacgt tcgggaagtt ccggcaggca
     4561 ggactggtat tggctattgt tcctctggca cttttcggag gtatgcttgc tcttaatgtg
     4621 cgtggtatga cgctgaatgt atcttctgcc gtaggattta tagcgatgtt cgggctttcc
     4681 atacaaaatg gaattatcat ggtatcgcag gtcaatgggc tgcgcagggg aggaatggaa
     4741 ctccggaaat cggtcataga aggggcacgc cagcgtttcc gacctattct gatgacttcg
     4801 atcactacga tactcggact tttcccggct tcgttggcaa ccggaatcgg tagtgacgta
     4861 cagcgtccgc tggcaacagt gattgtgtat ggattgatgt tttcaaccct tatctctatg
     4921 tttctgcttc cggctttcta ttatctggtt gagaacaatg ttttaaataa aaagaagaac
     4981 gatgaaaaag aatatacgat ataatatagt gctcttgctg ttaatggtgg aagccgtact
     5041 cattccggct tttgcgcaaa tgcctgaaat aaagctgggg cagtctattt ctttcgaaga
     5101 atatctgaat cgggtagcga aaaagaacct gagttattta gccgaaaaac tcaatgtgag
     5161 tattgctgat gcggaagtaa ttgcccggaa aatctttccg gatccggagt tggaatttga
     5221 agcaggtaat gagactttct cgttgggagt ttcctattca ttagaaatgg gaaataaaag
     5281 gggagcacgt attaagttgg cgcggactca ggcagaattg gagaaactgg tcctgcaaca
     5341 gggctttcag gatttgaggg cggaggctgc cgaccttttt ctagaagcaa ttcttcagcg
     5401 cgaattactt gaagtacaga aaagttctta tgagtatatg tatcagctga gtcagtcaga
     5461 tagtttacgt tatgtttcgg gagagattac ggagaatgat gtccggcagt caaaactgga
     5521 agctgtcacc ttgcttaata ctgtttacag tcaggaggcg gcttatcatt ccgctttggt
     5581 tttgttgaat aaacacatgg ggatgagtgc tgatacgctt catatccctt tgggaaattg
     5641 ggaagagcta agcagggact ttgctctgtc tgatttggtc aaagcgggac tggataatcg
     5701 catcgacctg cttgttgctc aaaaaagtac tgaagttact acccgggaat ataaactgac
     5761 gagagcggaa cgcagacccg atatcggagt atctgtttct tatgaaagaa actggaacgg
     5821 ctttcttcct ccgtcccgtt ctgctactgc cggtgtatct gttcctctga cattctcgaa
     5881 tataaataaa ggagctgtaa aagctgcaaa gtttcggatt gcccaatcgg agataatgga
     5941 aagagatatg gaattgcaga tacaggcaga gataacccag gcctggttca actatgaggc
     6001 tgaaaagaaa aagatagctc aatataaagc cggtgtactt gaagactcgc agaaggtgct
     6061 cgacggaatg gtatataaat acaaacgggg agaaacgagt attcttgatg tactggttgc
     6121 ccagcgtact tataatgaag tgcaacagga gtatctggaa acaatgaaag gatatgccgc
     6181 ttcactagta gcattggaaa gtgcttgtgg tatatgggat atatgctttt aacagttaaa
     6241 tatccggctt tactattgtg aattgcagca aagccggata tttgtatggt taccagtcag
     6301 cggtttcacg ctttatgtta aatcattgtg cgatattcct cctgtttttt cttagggagt
     6361 tttttgatca cttcttccac agagtggtca ataagttctt tgataagttt gtcactcagg
     6421 tttatttact tatctgtttt ccgaacttta atccgtacta ctgtgtcatt ttgacgagac
     6481 tggacaatgt tttattactt tcgattgtgt atctttgctg tagttaaaat ggacaaccgg
     6541 aatttatata ctaataaaca gaatattatg gaagcgaagt atatcactct gactaaagag
     6601 aatatcgaaa aagaacatat ttgctgtgct ttctccgata agaaatgcaa ggatagctat
     6661 gagttgaaaa agacatggct gaaaaatgag tttgagaatg gctatgtttt cagacggctt
     6721 gacgaacgtg caaaagtatt tatagaatat gggcctgccg aaaaagcttg ggttccggtt
     6781 aatgcaccta actatttaat gataaactgt ttttgggttt caggaaaata taaaggatgc
     6841 gggcatggca aagcactatt acagtctgct gtcgaggatg ccaaagcaca gggtagggat
     6901 ggcttggtga ctgtggtcgg tacctctaaa tttcatttta tgggtgatgc gaaatggtta
     6961 ttacgtcagg ggtttgagac gatagaaaaa ctaccctatg gtttcagtct tttggctttg
     7021 aagataaatc cggcagctcc tgatccgtca ttcaatggaa cagtatcaag tggagaatgt
     7081 gaggaaaaag aaggtgtagt cgtttattat acacatcgtt gtccgtttgc agagtttcat
     7141 gtccgtaatt ctttagtggg tgtgactgag aacaaaggta ttccattgaa gatagtcaga
     7201 ttggaaacga tggcacaagc acaaaatgca cctacacctg ctactatctt ttctcttttc
     7261 tataaaggaa agtttgtaac gacggatttg agtgcatgta tggagcaacg gtttgataaa
     7321 gcgttgggat tataatcttt cttattacag tatgtgtttc tcttttttga ttttctgttt
     7381 ttgtgctgtt ttgctctgat gagtgtggcg ggttaataat tgtctggtgt ttatttagac
     7441 tggtcggttc gatttttcat gtgctgctct gatcttatgc agattcctta atagaatcgg
     7501 cagtttattt gtatgttgag atgttttgtt ttatgtatgt gacatatgct tgatttttag
     7561 tattttattg tatgtggttg gtggggaaga cttgatggct cttgactttt ataatcacta
     7621 acttttctta ttttagttca tttaaatatg ttcaattctt gcattttatg aaactatgtt
     7681 ttacttttgg ggagtaaagt cattgggatt ataatgaaaa gtattcgctc ggttatttgt
     7741 ttttgtttgt ttttgtttgt gtttaaccag ctccttttcg ccgacaaaac tatagagaat
     7801 gattcgctat ataccagtga gtatataagt cgaatttata tggcagaacc tgaacgggct
     7861 ttaagtttgt tggatggagc tgaaagtaag aagactatcc ctctgcgtat tatacatgaa
     7921 ttacgcagca gggtttatcg taatatgtat atgactaaac tggctttttt gtatgccaaa
     7981 aagtcttatt tgctggattc cgtttctcag aaagatccta agcacttgtt gaccatgact
     8041 gtcgacctgg cagaattagc agtgcttatg agtgaccata aagagagtat gaggtatgct
     8101 cttgatggta tcaagctagc acaaaaagaa aaggataaag gggctgaaag taagctgttg
     8161 ttttgcattg gtgaaaataa atggcaattg tctttcaaag aggaggcata tgactatttt
     8221 gacaaagcta tcaaattgct tcaaggtaca agttccaaat tggaaatgac tatgctttca
     8281 tacttttatg ggatgaaaat ggattatctg ctcaatgatt cccgtagtaa agaagcattg
     8341 gaggttgggt tgaagcgcga aaagctactt aaagatatag ctaaattacc ggaaaaaaca
     8401 aaaggctttc ttgatctgca atatacttac ttgtatgcaa aaatgtcgta tatctgctat
     8461 ctggaaggaa agtatgatca ggcggaaaaa tattatcaac aatatttgtc aacagagaat
     8521 tcacagacac cggatggaaa aacctatgcg ataccttatc tgctagtgtc taaacaatat
     8581 cagaaagtcg ttgatcaatg tcaggatttt aagaaattga tgcaagagca ggatactgtc
     8641 aacttgcagt atattagtat ccttcagaaa gaggtgaaag cttataaagg cttgaaggat
     8701 tttgaaaaag tagcagcatt acgtgagtct attatttcta ttattgatgg tattaacagc
     8761 aaggataagc agaatgcggc tttggaatta aatgctattc ataaagctga cgagcaggaa
     8821 gaatatattg ccgaacagac tttacagtta agaatcagaa acatatcact tgcttttttg
     8881 ggatgtgtca cttgtctcat tttatttgtg ctatggcgga tttggcgtca tacgattatt
     8941 gttaaatata aaaacaaaat gctggcaaag tttatcaatg agaaactggc tggaaaagta
     9001 gagaacaaac aattattcat agatggagat gcggaagatc cgatagctgt tccattggac
     9061 ttggaaccgg aaactggctt ttccgaaaaa gacgatttat ctccggatga agtagtggag
     9121 agtagggagg aagaggatga gaataagaaa attttcaaag aactgaatcg tattgttgtt
     9181 caggatcagt tatatctgtc tccggaattg tcgagagagg atctggctca gattgtacat
     9241 ttgaataatg cgcgtttcgc ccggatgatc aaggaaaaca ccggaactaa tttcaacggg
     9301 tatattaatg aacttcgtat taactatgcg attcagttat tgaagcaaca tcccaattat
     9361 accattcgtg cgatagctga tgaagccgga tttaatagta cgcctattct gtacagtatg
     9421 ttcaagaaaa agactggtat gactccttac gaatttaaaa aaacgcagga atccttaggt
     9481 tgattttggc tttttcgata aacaattttc cgttttatcg gtttattctt atgataacta
     9541 aatataaacg gaaatggtgc aagttaggat aaagcgagtg tacgaagact tttcagagac
     9601 cgacggatat cgggtgctgg tagataaact ctggccacgt ggaatcaaaa aagaatggtt
     9661 gaaatatgat tactgggcaa aagatataac gccttccgca gcactgcgca gatggtttca
     9721 tgaagatatt ccgggtcact ggaatgattt tgtcgtaatg tatcagaagg aactggaagc
     9781 ttctcaagct gttgccgatt ttctgactct tatcaaacct catccggtga tcactttgct
     9841 ttatgcatcc aaagaaccgg tttataatca tgcccgaatc cttcgtgatt atttggaaat
     9901 gcatctgaaa gagtgaaatt aaagtaattt ttatctcttt ccgctttcag tcgttcactc
     9961 aatttcctac ctttgtaatc taaatcaaaa tcgtgtgtcc atgaagtata aattattagt
    10021 tcttgatgta gacggaacgc ttctcaatga tgcaaaagaa attagtaaac gtacattggc
    10081 tgctttgctg aaagttcagc agatgggagt acgtatcgtg ttggcatccg gccgaccgac
    10141 ttacggtctg atgcctttag ccaaatccct agaactcgga aattatggag gttatatcct
    10201 ttcttataat ggttgccaga taattaatgc tcaaaacgga gaaatactgt ttgagcggag
    10261 gattaatccg gaaatgttgc cttatctgga aaagaaggca agaaaaaata atttcgcact
    10321 gttcacttac catgatgata cgatcattac tgacactccg gagaatgaac atatccagaa
    10381 tgaagctcgc ttgaataatt tgaaagtgat caaggaagag gaattttctg tagcaattga
    10441 ctttgctccg tgtaagtgta tgcttgtcag cgatgacgag gaagcgttgg ttagtctgga
    10501 aggacactgg aagagacggt tgaacggagc tttggatgtt ttccgttccg aaccttattt
    10561 tctggaagta gtgccgtgtg cgattgataa agccaacaca ttgggagctt tattggaaga
    10621 actggatgtg aagcgtgaag aagtcatcgc tataggagac ggtgtgtgcg atgtaacgat
    10681 gattcagctg gcaggactgg gagtggcgat ggggcattcg caggattcgg taaaggtctg
    10741 tgcggattat gtgacagctt ccaatgagga agacggagtg gctctggctg tcgaaaaggc
    10801 gataatagcg gaagttcgcg ctgcagagat tcctttggac cagttgaatg cacaggcgcg
    10861 tcacgcattg atgggtaatc tgggtatcca atatacatat gccgacgaag accgtgtaga
    10921 ggcgacgatg ccggtagatc accgtacccg tcagccgttc ggtattttgc acggtggagc
    10981 tacgcttgca ttgggagaaa cagttgccgg actcggctcg atgattctct gtcagccgga
    11041 tgaaattgtg gtaggaatgc aggtcagcgg aaatcatata tcttctgcgc acgaaggtga
    11101 tacagtacgt gcagtagcga cgattgtaca caaaggacgt tcctcccatg tatggaatgt
    11161 ggacgttttt acttcaacca ataaactggt gtcctctata cgggtggtca acagtgtgat
    11221 gaaaaaaaga tgattgacga aaaaagtaac ttgacaacta ttgatgcact tattcagcgg
    11281 aaacagccct ttgctgttta tcgtgttccc ggggagaagt atcctcgtct gttgacagaa
    11341 gatgtcggag ctgtccgctt gattttcgat ttgaaagaac tgaatggaca aagaggattt
    11401 gtgattgctc cgttccgtat agataagtca tgtccgattg tgttgataca gtccgacagg
    11461 actggacaac cgttgcctat ggaaatcgtg gcagaggaag agcaggactt gcaaagttat
    11521 ccggaggaat cttttcatac cctttgtact gggaagtatg cgacctgttt tcatacattt
    11581 attgaagcct tgcgtgatgc tacctttgat aaactggtgc tttcccgtag tctcactatt
    11641 ggaaagaatc cggagttttc cccttcagct gtttttcgtg cagcttgtca acgttatatt
    11701 cattcctata tctatctgtg ttatactcct cagacgggcg tgtggctggg aagtaccccc
    11761 gaaattatat tgtcgggcga aaaaaatgaa tggaacacag ttgccctggc aggaactcaa
    11821 cctttgcaga atggtaaact tccgcaagta tgggatgaca aaaaccgtca ggagcaggat
    11881 tatgtggcgt cctatatccg tcggcagctt ctttcgctgg gcattcgctc cacagagagc
    11941 ggaccttatc cggcttatgc cggtgccttg tcacatctga aaactgattt ccatttctct
    12001 ttgaaagata ataaaaatct gggagacctt ctgaaagtcc tgcatccgac tcctgccgtg
    12061 tgcggactgc ctaaagaaga agcctaccgg ttcattttgg aaaatgaagg gtacgatcgt
    12121 aagtattatt ccggttttat cggttggctc gatccggagg gacgcacaga tttgtatgtg
    12181 aatctgcgtt gcatgcacat tgaagacgag caattgacac tgtatgccgg tggcggattg
    12241 ttagcctctt cagagttgaa tgatgaatgg caggaaacgg aaaagaaatt gcagaccatg
    12301 aggcgtattc ttgtgtctgc tccaataatg atgaatcact aacaagctaa tcactatcaa
    12361 tatgtattcg gacaagaaaa atatactcca gttggtcgcg ctgcttgagg cgcatggaat
    12421 tacgaaagta gtgttatgtc ccggtagccg taatgcacct attgtgcata cgctgtctac
    12481 tcatccgggt tttacttgtt atgctatgac ggatgaacgg agtgccggtt attttgcgat
    12541 tggtcttgcg ctgaatggcg ggcatcctgc tgccgtttgc tgtacttccg gtacagcgtt
    12601 gctcaatctt catcctgctg tggcagaagc gtattatcag aatatacctt tagttgttat
    12661 ctctgccgat cggcctgctg cctggattgg acagatggcg ggacagacat tgccgcagcc
    12721 cggtgttttt cagacattgg tgaagaagtc ggtaaacctt ccggagattc agacagaaga
    12781 ggatgaatgg tactgtaacc gcttggtgaa tgaagccttg ctggaaacca accatcatgg
    12841 aaaaggtccg gtacatatta atattcctat atccgaacct ttgttccagt ttacggtgga
    12901 gtcgcttccc gaagtacgtg tcattacgcg ctatcagggg ctgaatgtat acgaccggga
    12961 ttacaatgac ctgatcgaac gcttgaacag atatcagaag cggatgatta ttgtcggaca
    13021 gatgaacttg atttacttgt ttgagaaacg gcataccaaa ttgttatata aacatttcgt
    13081 gtggctgacc gagcatatcg gtaatcagac agtacccggt attccagtga agaattttga
    13141 tgcggcgctt tatgcgatgc ccgaagagaa aaccggccag atgactcccg agttattgat
    13201 tacttatggc ggacatgtgg tttccaagcg gttgaaaaaa tatcttcggc agcatccgcc
    13261 taaagaacat tggcatgtgt ctgctgatgg agaagtggtt gacctttacg gttctctgac
    13321 taccgtcatc gaaatggacc cgtttgagtt tctggagaaa atagctccat tgctggataa
    13381 ccgcgtgccg gagtatcccc gtgtatggga gaattattgc aagaccattc ccgaaccgga
    13441 gttcggatat tcggaaatgt cggctatcgg tgctttgata aaagcattgc cggaatcatg
    13501 tgcattgcat ctggcaaata gttctgttat ccgctatgct cagttatacc aggttccttc
    13561 tacgattgag gtatgctgta atcggggtac aagcggcatc gaaggctcgt tgtccacggc
    13621 agtgggatat gccgccggtt cggataaact aaattttata gttataggtg accttagttt
    13681 cttttatgat atgaatgctt tgtggaacat caatgtccgt cccaatctac gcattctttt
    13741 gctgaataac ggaggagggg agattttcca tacattaccc ggactggata tgtcgggtac
    13801 atcgcacaag tatattacag ccgttcacaa gacatctgcc aaaggatggg cggaagaacg
    13861 cggattcctt tatcaacggg tagagaatga agaacagctt gccgaagcga tgaaaacctt
    13921 cacacaaccg gaagccatgg aacaaccggt tctgatggaa gtattcagca ataaaaataa
    13981 agatgcacgt atactgaaag attattatca tcaactaaaa caaaaataga ttatgtcaac
    14041 acaaagagaa tggacaacca tcagagaata cgaagatatc ctctttgatt actataatgg
    14101 gattgcccgc atcaccatta accgtgaacg ctatcgaaat gcatttactc cgactacaac
    14161 ggctgaaatg agtgacgcat tgcgcatttg ccgggaagaa gcggatattg atgtgatcgt
    14221 gattacggga gctggtgaca aggctttctg ttcgggcggt gaccagaatg tgaaagggcg
    14281 tggcggctat atcggcaagg acggtgttcc ccgtctgagt gttctggatg tacagaaaca
    14341 aatccgcagc attccgaaac cggtaattgc tgccgtaaat ggatttgcca ttggtggcgg
    14401 acacgtgctt catgtagttt gcgatttatc gattgcttcg gagaatgcga tcttcggaca
    14461 gaccggtcct cgcgtaggta gctttgatgc aggtttcgga gcctcttatc tggctcgtgt
    14521 cgtcggtcag aagaaggcac gtgagatatg gttcctttgc cggaaataca atgcgcagga
    14581 agcgttggat atgggattgg tgaataaagt agttccattg gagcaactgg aggatgagta
    14641 tgtgcaatgg gcggaagaaa tgatgctgct cagtccgttg gccttgcgga tgattaaagc
    14701 cggattgaat gccgaactgg acggccaggc aggtattcag gagctggcag gggatgcgac
    14761 cttgctttac tatctgacgg atgaggctca ggaaggaaag aatgcatttc tggagaaacg
    14821 taaacctaac tttaagaaat atccgaagtt cccttaaaca atggattgca aaatagacat
    14881 tattccgcgg gtgcttcatt tcaagcagcc ggccggaact tcacgaggca catacacaac
    14941 gcgaaaagtc tggtatcttc attttactgc tcccgaattt cccaattggg tagggatcgg
    15001 ggagtgcgct cctctgccaa atcttagctg tgatgatctt cccgattacg aggaagtgct
    15061 ggctaaaatc tgccggcagg tagagaatca gggaggtaag ctggacatgg aagctctatg
    15121 caagtaccct tccatccttt ttggcttgga gacagccatt cgtcactttt ttgaaggaag
    15181 ctgggctttg tgggatacac ccttctcacg tggggaagca ggtattccga taaacgggct
    15241 tatctggatg ggtgacttca atagaatgct tgctcagata gagaagaaga tggaggcggg
    15301 attccgctgt ataaagttga agatcggtgc catcaacttt gaagaagaac tggctttact
    15361 ccaacatatc cgctctcact attcttctaa agaaatagaa ttgcgtgtag atgccaacgg
    15421 agcattctca ccaacagatg cgatggagaa attgaaacgc ttgtccgaac tggacttaca
    15481 ttcgatagaa cagcccattc gtgccggaca atgggaagaa atggcacgtc ttacttccga
    15541 atctcctttg ccgatagctt tggatgagga actgataggc tataatacct gggaagaaaa
    15601 gcaaagatta ctttcggcta tccgtccgca atatattatt atcaaacctt ctcttcatgg
    15661 cggattagcc ggtggcgagg agtggattgc agaagcggag aaactgaata tcggttggtg
    15721 gataacttct gctctggagt ctaatatcgg tctgaatgct atcgctcaat ggtgtgctac
    15781 ttttcagaat ccattgccgc aagggttagg caccgggtta ctctttacag ataatgtaga
    15841 gatgcctctt gaaatcagaa aagattgttt gtggttttgt aaatgatgat attcgaccga
    15901 caaaaacagc gtttgttgct ggagggaaag gaatatactc cgggcgatat acatagcctt
    15961 gtagcagaag gtgagggaaa ccacccttct gctatatggg acttgtatct ttttctaaac
    16021 gaatggttta atgatgatcc tgtgatcact gtacatactt ccggttctac gggggcacct
    16081 aaagaattgc ttgttcgcaa agatcagatg atacagagtg cacgcctgac ttgtgagttt
    16141 ctggatttaa agcagggtga aacggcatta ttgtgtatga accttcgcta tatcggggcg
    16201 atgatggtag tcgtccgttc tttgattgcc gggttgaatc ttatagtacg tcgggcttcc
    16261 ggtcatccat tggcagatgt ggacactcct ttaaggtttg cggctatggt gcctttgcag
    16321 gtgtataata catttcagat acccgaagag aaagagaaat taaagcaaac ggagatttta
    16381 attataggag gcggagcagt tgacaaggct ttagaggaaa aaatcagaaa tctgtccaat
    16441 gctgtttatt caacttacgg gatgacggaa accctttctc acatcgctct tcgccgtctg
    16501 aatggcgcag cagcatccga tcgttattat cctttttcat ccgtagagtt gtttttgtct
    16561 tcagaaaata ctttgatgat taatgctccg cttgtttgcg atgatactct gcagacaaat
    16621 gatattgccc gcatttatcc ggacggtagt tttacgattc tgggaagaaa ggataatgta
    16681 atcaatagcg gaggaattaa agtgcaggca gaagagatcg aaaggttact tcagtcgtct
    16741 atccctgtac cgtttgtgat cacttccgtt ccggatcggc gtttggggca ggctgttact
    16801 ttattgatag aagggcagat ggagataagt gcgctaggga ctaaattgga atcagtctta
    16861 gcatcttatt atcgtcctaa atatatttat acggtaaatc atattcctca aacgggaaat
    16921 gggaagatta atcgtaaaga gtgccgtgtt ttagcagaga gcttacagtt gctcgggaga
    16981 caggaataat aaaaacagcg ggaggtaatc tttcaactcg ttccgcagga gttccattgt
    17041 tttttgttta taccgattaa tggattttac gctgagattc atttcttcgg caatttccgc
    17101 atgtgttttg ccttcaaaga aacttttcat aaatacggtg cgatagtttt ccggaagctt
    17161 atttaatgtt tcgtatagca ttcggtataa ctcatcaagt gtatatacac tatctgtttc
    17221 tgtttcatat agaggagctt tcttttggat attttcggca taactccatt catactcctg
    17281 atgtttcaga aagttcaaac agctgttttt tacacacatt tttatatatc ccaatgctgt
    17341 ctctgattgc aaatcgaaag agtcggtatc caacttgtcc catagggagg tgaatacatc
    17401 cgaaacaatg tcctcgcgga cttctttatc atctacaaat ctttttgcat acaggcagaa
    17461 aggggcataa taatcctcgt aaagttgttt gaaagctctt tctttagtct gtctggaaaa
    17521 agatattttc attattttga gattctgtag tttttcattt tacttcaaat atataataag
    17581 aaaatcagca tttcctaaaa ttttctttct tttttcgttt ttggtatgaa gctgtggaaa
    17641 ataagatagc ttaaaaaata aaataaaaaa aagtatgtta tacctgtccc ttttcgatta
    17701 cctcagttgt actattagtg taattgcaat taaaagataa gattttgaaa gagaatatgg
    17761 aaaatatgaa tccggaatca ttgctccgaa aagcgcaggc attaggagag gatattaagg
    17821 aaatggagtc tattgatgta atgggtgcct atcaacaagc acagacccaa ataaagacaa
    17881 acagaagaag gagtatgtat aatcagttga tgcgttatgc tgcattcttg actatacctt
    17941 tattactttc ttctttgatt ttgggatatt tatattgggg agcaacggat actgaagaga
    18001 agtatgcaga agtcatggcg gctacaggtt cagtcattcg ttacgaactt cctgaccatt
    18061 cggttgtctg gttaaactcc ggtagtactt tacgttatcc taccgttttt aagaaagata
    18121 atcgtaatgt tgaattaaaa ggtgaagcct attttgaagt agaagcggac aggaaacggc
    18181 ctttttacgt caatactcct gccgggttaa gtgtctatgt gtacggaacc aaatttaatg
    18241 tgaatgctta cgaagatgat aatagtatag aaacggtatt agaaaagggt aaagtaaacg
    18301 ttatttcacc ggacggaaaa acaacagttc agttagctcc aggagaacga ttgctttata
    18361 ataaggtaga tcagaaattg ttgaagggaa aagtggatgt ttatgaaaag gtggcatgga
    18421 aagacggtaa gttgatattc cgcaatgccg agttgggtga aatattcaaa cggctggcac
    18481 ggcattttaa tgtagatatt cagtttaata atatatcggg aaaagaatat aaatatcgtg
    18541 cgaccttccg taatgaaaca ctgccacaga tattggatta tctggctaag tctgctgcct
    18601 tgaagtggag aactgaggag gcggtacaac aggcagatga tacattcaca aagaaaaaga
    18661 taatagtaga tttatattag taaccataaa aatgagaata gcctatgaga taacacaaag
    18721 atcgtaaaaa aaggaagaaa gctgctacca acagctgtct tcccccaatt tttcagattc
    18781 gcggtaagga gtcttgcaaa cgctaaccgg aatcaaacca cagttcatta tagtaataaa
    18841 ctttagttaa ccgcaaatgt atgaaaaaaa atcattcatt tattgcatta tatcctaaat
    18901 atgctttaaa tctaaaacta cctttagtta tgaggattag tctggcacta ctttttgcag
    18961 tcgttttaca actatctgca gagaatggct atgctcaacg gacgcatgtt gccatttcta
    19021 tgaacaatgt atctgtagaa caggtactga ataaaataga agaagcttcc gattatgttt
    19081 tcctttacaa tgacaaaacg attcagaaga atcgtattgt ttctgtgaga aataaatcag
    19141 gtaagattct ggatattcta gatgatattt ttaaggggac cgatattacg tataccgtag
    19201 ttgacaagca gattatttta tcgactaata aaatgcaact tgttcagcag gaaggacaaa
    19261 tccaaataaa aggagttgtg aaagatgctg gcggagatcc cttgatcggt gtgaatgtga
    19321 aagtgaaaga ttctacggtc ggtactatca ccgatataaa cggaaacttt acgctacaga
    19381 ccaggaaagg agatattctg gaaatttctt atgtgggata tgccacgaaa acagtaaagg
    19441 tacagaatgc ccaagttctg aatattgtgc tgacagaaga tacagaagta ctgaatgaag
    19501 tcgttgttac tgcattgggt atcaagaagg aagctaaatc tttgtcatac aatgtacagc
    19561 aagtaagcaa tgccgagatt acacgcattg cagatgccaa cttcgtcaat aatctgaacg
    19621 gtaaagttgc gggtgttaca attaactcat cttcagctgg tgtcggtggc tcttcacgtg
    19681 tagtgatgcg tggaaccaaa tcattgaatg gtaataacaa tgctctttat gtggttgatg
    19741 gtatcccgat gagtgatatg agtgccgctt ctacacagcc tacggactca tacgaaggtg
    19801 ccggtcagtc cggtgatcct atttccggtc tgaatcccga ggatatagag agtatctctg
    19861 ttttgagtgg accgtcagct gcagctcttt acggtagtgc cgctgccaat ggtgttgtga
    19921 tgattactac taaaaaaggt agggaaggac gtacttcagt cagcatatcc aataatacga
    19981 ctttctccgc tcctcttgtc ttgcccgaat ttcaaaatac ttatgggcag acagaagtgg
    20041 gtagttacta cagctggggc agtaaattga atacgccgag cagctatgat cctaaagact
    20101 tctttcagac aggtgtgaat gtaacaaatg ctgccagtct ttctacaggt actgacaaga
    20161 atcagactta cttatcttta ggtactacca atgccaaagg tattatccat aataatgact
    20221 acgaacgtta caatgtcact gtccgtaatg ttgccaagat gctgaaagat aagctgactc
    20281 ttgacctgag ttttatgctt agctctgtaa aagaacaaaa tatgacctct cagggacttt
    20341 attataaccc gttagtacct ctttatctat ttcctgcggg agatgatttc tccaaagtac
    20401 aggcatatca gcggtatgat tcggaacgaa atttactgac tcagtactgg ccttacagca
    20461 caagtctggc tttacagaat ccatactgga ttaccgagca tattaaaata cctaatcata
    20521 agaaccgtta tatggcaact gcatcggcaa aatatgaatt tgctgactgg attaatgtaa
    20581 cagcccgtgc caaaatggac cgcaacaacg aacgccgtga gcgcatgtat gatgccggaa
    20641 caaatacttt gtttgcttct aaatacggtt attactccaa gagtaatatc gagaatcaac
    20701 agatatacgg tgaattattg ctgaatatta ataagtactt tgtcgataat accctaaatg
    20761 taacagctaa tgtgggtggg aactttgaaa acaatgatta tcagtctgat tatttcggag
    20821 gcaaactgaa gtcggtagcc aacctcttta cttttggcaa cgtggatact tcagagaaga
    20881 atctggccaa ccaatatggc tatcatttga aaaaacgcgc catattcggt agtgctcaga
    20941 tcggttacaa gtctatggct tatctggatg tgacggctcg taacgactgg tcatctacct
    21001 tcaaagggac gaataccggt tctttcttct atccgtctat cggtctttcg gggattatca
    21061 cagatatatt ccgttgcagt acggatatta tgccatacat gaaagtacgt atttcttatt
    21121 cggaagtagg taattcaccg gatgtatttc tggctattcc gacttatgcg ttggttgatg
    21181 gcgttcctgt tactcagtcc cgacgtccta accccaatct gaagccggaa cgtaccaaat
    21241 catgggaagc cggatttaac tttgtcttct tcaagaaccg tttgagattg gatggatcta
    21301 tctatcagtc acgtacctac aatcagttct ttgaacgtac cctttcttct actaccggct
    21361 ataaatcgga agtagtcaat ggcggtcgtg tagataataa aggtatcgaa ttgtctttgc
    21421 gttttgagga caaatgggga aattttggct ggagttcgta tctgacctat tcattgaacc
    21481 gaaataaagt ggtggaattg ctgcgcaact atgaagatcc ttatacgcac gaacttactt
    21541 ctttggatag aattgatatg ggcgggacaa gtatgtataa aatgatactg acagaaggcg
    21601 gatctatcgg cgatatttat gtgaatacgc ttcgcacgga cgaacatgga gctatctatg
    21661 tccatccttc ggaccaggtt gtagttactc agcctgatga atttgtaaag gctggtaata
    21721 gtgctcctaa gtataacctc ggttggggaa acacattcag ttacaaaggg ctttcattgg
    21781 gattcctgtt cacggcacgt gtcggtggtg tagttgtatc acagacacag gcgacgatgg
    21841 acgcatacgg ctcttcaaag gctacagcta ttgcccgtga taatggcgga gccattgtta
    21901 acggtcgtcc aatcggtgcg gaagattact atacgaaaat tggaggtgca ggtgctcagg
    21961 gtggtattgg ttctatgtac acctacagtg cgactaatgt ccgtttggct gagttatcgt
    22021 taggctatga tattcctatc aacaagtatg tggactggat taaggggttg aacgtatctt
    22081 tcatcggtaa gaatctcttt ttcctttata gaaaagctcc gttcgatccg gaactgacag
    22141 caagtacagg cacttacttt caaggtatcg acatgtttat gtcgccaagt ctgcgtaatt
    22201 tgggattctc tgtgaaagtt aatttctaat caaacttata aattgtagaa gatatgatat
    22261 taaataaaat actatcatgg aacaaacttt ccattctcgg gatatctttg atgctattaa
    22321 ataacatttc gtgtatcgac tatgaggata acgtaaatcc gaatgaagtc accgaggaaa
    22381 tgatggaagt agacaacttg aagacgggtg ctttcttttc gcaaatgctg cgtcgggttg
    22441 taatcataaa tgatggcgac aagctcgact ctgactatca gattgctcag aacttatcgc
    22501 atgaccttta ttcgggctat attgccgcta ccttaggatc taccaatcat aacgggcagt
    22561 ataactttca ggaacaatgg gtgaatgcca cttttgatta tgcctatacc ggaattatgg
    22621 caccatggca aagtattcac aaaatagcca ctgaacagga actgccggaa gttgacgcat
    22681 tggctaccat cgtaaaggta gaaggcatgc accgtattgc tgatacattt ggtcctattc
    22741 catatgtaaa ctatggctct tccagcttat atgacgcatt ggatttggtt tataataagt
    22801 tttttgaaga actggataat gctatcgaag tattgagcaa ttatgtgaac ggaaatgtgg
    22861 atgctaagct gatgagtgac tatgactgtg tatatggggg ggacgtagag aagtgggtga
    22921 agttcgccaa cacactgcgt ttgcgtcttg ctatacgtgt ttcatatgcg aatcccacac
    22981 tggcagaagc acaggcaaag aagtcgatgg aaaacatgtt cggctttatc gaaagtaaag
    23041 cggaacgtgc cgaactttcg cataattcat tggaatatca tcatccgttg cacgagattg
    23101 cctataactt caattcgggt gactgtcgtc cgggtgctac catcgtagcc tatttgaacg
    23161 gactgaatga ttcgcgaatc agctcttatt ttacagcagc cgatgacggt gaatatcatg
    23221 gcgtacgtat tggtatcaca acaagcaata tgagcaatta tcaaggcaat aaaatctcta
    23281 atctgaatat taaccgtgct tctactccgg tagtatggat gacggctgcc gaatcgttct
    23341 tcctgcgtgc cgaaggtgca ttacgtggct gggatatggg tggaacggcc aaatcattct
    23401 atgagcaagg tgtacgcatg tcgtttgagg agaataatgc cgccggtgta gacgattatt
    23461 tggctgatca tacttcgact ccgggtgctt ttgcagacaa tgtgggtagt gataattata
    23521 ctttcagcag cagggttact cctgcatggg atgataatgc cggatttgaa gctcagttgg
    23581 aacgcatcat tacacagaag tggattgcca attatcccga cggtcccgaa ggctggagtg
    23641 aatatcgtcg tacaggctat ccggaagtta ttcctgtagt aagaaacagt agtaatggta
    23701 cgattgatac ccagttacaa gtccgccgtc tgccttatac acgcgacgag aagatcaaca
    23761 atgctagcgg cgttgccagt ggtatatcgg ctttgggtgg taaggatacg ggtggagcta
    23821 aactctggtg ggacaaaaaa tcccgataac aggagaatgg acattgttta attctaaaaa
    23881 cactaattac gatgaaaaca aaaataacag gtttactgac tttccttatc ggaacattct
    23941 ttttctatag ttgtgatacc gatgtggaag cgttagaaat tcagaagctg aaaacatatg
    24001 acgagcagta ttttgagaat ctgcgtgctt tcaagaaaag cgatcatgag ataagttatg
    24061 cttattacga agcgtggtca ccgattgaag gtgtgacagg ctataaagat cccgcgtcgt
    24121 ggggtgaacg tatggtagga ctacctgaca gtatagatat tgtaaatctt tggatgggaa
    24181 taccgacagc agagacacat ccgatagcat atgcggatat gcaatactgc cagcggaaat
    24241 tgggtacacg ttttgtcatg catgccgatg cttctcatta cagacaccag tttaccgttg
    24301 atggggttga ttatgatctt agccagaata aggacgatga agcgatggct gcatatgcaa
    24361 aatggattgt gaatcaagtg ttggaaccgg gacttgatgg agtagacgtt gactgggaag
    24421 gttggagtgg ttccgatttg gtcagattga taaaggaact tggcaagtat tttggtcctg
    24481 aaggcgaaca gccggataag ttgcttatcg ttgactactt tagtggaaca ccaccaacag
    24541 acatcatacc ttattgtgat tatatcgttc aacaggctta tagtgatcaa gtggggttct
    24601 tgactcaacc cagtaacttt ccacccgaga agatgattta ctgcgaatcg ttcggagtat
    24661 tctatgccga tgggggacaa cttatgaact atgcacgttg ggaaccgtcg aaaggccgta
    24721 aaggcggttg tggagtattc tacttaggaa gaaattatta ttcttcatcg ggtatacctt
    24781 ataatgaatt ccgggaggct attcagataa tgaatcctgc tgtaaatgag taaacaatga
    24841 ataaataaga atcatga
//
