LOCUS       c00058_gnlPro..        16056 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DBCIDAOH_58.
ACCESSION   c00058_gnlPro..
VERSION     c00058_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 11:37:41
            Original ID  :: gnl|Prokka|DBCIDAOH_58
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16056
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16056
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5998:12461]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5999..12461
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..16056
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16056
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             complement(185..1915)
                     /locus_tag="ctg58_1"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLVETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYIGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRETYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVMMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSEEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEESYAMWTNRMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPEGEKITILKMADNRPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(1934..4360)
                     /locus_tag="ctg58_2"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLRKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETTFS
                     APGHEELGRMLEIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NAIEQGRQSMVAEGITMSRYPSSVHQFISSYSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGSSALQDLMYIMTLEFA
                     VEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRGYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKVSGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLDERGEGTARLVLPEGTTGIFIWDGKEIPLKPGEQVISLSSRH"
     CDS             complement(4482..5270)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_3"
                     /sec_met_domain="Fer4_7 (E-value: 4.9e-11, bitscore: 32.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.1e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1e-05, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIVYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLNQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNL
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             complement(5276..5851)
                     /locus_tag="ctg58_4"
                     /transl_table=11
                     /translation="MRFDENFNVSLSLNPKREMIKVMKKYLLASLLALLAFVGKAQEDN
                     SDIVKVGDTMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             complement(5999..6580)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_5"
                     /sec_met_domain="POR (E-value: 2.1e-43, bitscore: 138.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDKLPHKVVLDVEEIAKEAGSVRAANIVMLGAATPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             complement(6577..8178)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_6"
                     /sec_met_domain="POR_N (E-value: 1.3e-14, bitscore: 44.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.8e-19, bitscore:
                     57.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRIYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNYEEMKAIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             complement(8283..9332)
                     /locus_tag="ctg58_7"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TIDALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKKAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLQRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             9698..10312
                     /locus_tag="ctg58_8"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKKK"
     CDS             complement(10401..12461)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg58_9"
                     /sec_met_domain="Succ_CoA_lig (E-value: 5.3e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 1.4e-21, bitscore:
                     66.9, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPGTELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(12541..13293)
                     /locus_tag="ctg58_10"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHAHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSND
                     ADRIAALEIPVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHL
                     QIFEVSATKGDGMDAWCDWLQTESAKCK"
     CDS             complement(13323..13670)
                     /locus_tag="ctg58_11"
                     /transl_table=11
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLA
                     FALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKE
                     LRVKSIVIKKE"
     CDS             complement(13683..16055)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg58_12"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.4e-09, bitscore:
                     27.7, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="IQHRIPLASNHLLYSTKICLNLTNSSYICAMAKNKVYALIIQGLV
                     QGVGFRPFIYRIAKDLGMKGCVENMNNGVRILVAATPDDRDLLISRIRTEHPRVAYIHR
                     ISYTSTEMDEDDFDDFTITPSHSESDEVTQVSPDIAVCADCMRDRTTQPHRIGYPFINC
                     THCGPRFSIIRDLPYDRSQTTMGGFLMCPDCEKEYTNVIDRRFHAQPVACNHCGPTYYA
                     TYNEETYIYYETLLKLTSRLLLGGEVIAAKGIGGYHLICDASNERAVARLREIKQRDTK
                     PFAVMFRDLEHLQVYTVTEPMEERCLVSWRRPIVLLRQRSRLASGINPGMHTLGCMLSY
                     MPIHYDWFARTGIPALVMTSGNLSDLPIAITPEDAEAQLAGKVAILLHHNRPIHNRVDD
                     SVLQVCGGQPCLIRRSRGYVPEPFFTDTNVEGIMAFGAEKVNTFALGKGETILQSQYIG
                     DLKNWETFRFYTESMEQFRHLFRFNPQRLVCDLHPDYLSSQEAERISKSLSLPLLKVQH
                     HHAHAAACMLEHGLNEPVLAIVMDGTGLGDDGKVWGGEFFFCDRAKYRRLSHFEYVPLP
                     GGDKAAEEPWRMVVAYLWHYFKDEPSGIPYPADFVERIGTERIAMLERMMEKGVNTPYT
                     SSAGRLFDAVASLLGICDVSSHQAEAPVLLEQAAMGERNAYAYPVSAEGEEISFYSLFE
                     ALLHDKTNEVPVSLISARFHTTLASLFVQKARLLIKRTKATQVVISGGCFQNKLLTESM
                     RRQFIMAGVPVYIPSRIPCNDGGIAVGQLTIASVTPF"
ORIGIN
        1 tagaaacata cgtaaagatg cgccctttgc gccctaacct atcagcaaca tccctaatac
       61 gggatacaaa aaagtcaatg ggacacggcc gtaaagtcat tgagaaacca tctctattcc
      121 attgacttta ccaccgtttc ccattgagat actatcgcaa accagacact tcaaggacgg
      181 aaactcattc cccgaaaaga aacttacaat cccgttcggc cgccggtctc gtccaatcct
      241 gcgggatcat ttgccattgg tttaaaggtt gtgggctaag tacgcccttt tcctttatat
      301 attgaatcat ataataacgg aggtctttat cggtcgaatg aatgatacga ctctttaact
      361 cgtcttgggg aataccggcc cctttcgtca ataactcacc tcctccatta cctcggtaag
      421 agttgagagc tactttatac gttttattct cgtcgaaagg cctgttatcc gccattttca
      481 agatcgtaat cttctcaccc tctggtttcg ttacgtccac ggtgtaaatg ataccagctg
      541 cggagtcaaa gttaaaactg aagttgacga atgagacata attctcctgt cctttctttc
      601 tctctttcaa taataagaca tgatcgtccg gagatttcat ccggttggtc cacatagcgt
      661 atgattcctc caagaaacct ttgatctcgg ctcccgtcaa attcatcgta taaagcatat
      721 tctcatattt gtaaagactg aacatatcgc tgatcgtgat atccccttta tctatttttg
      781 cgtcaaagga taacggggcg gcaaaagaga cgtccgcacc agtcaactcc aattgtaaag
      841 agtgaataaa atcaataaaa gcggatggcc caaagtaagc gggacgggtc gcgatactct
      901 ccgtaaaagt tcccaccttc tcggagacaa aatcattcac cgctttgtat tgcggagcga
      961 atttctccat aaactcctcg ctaggctcca acttatccac atccgtcaaa acacccgata
     1021 cttgtttatc caaaaccttt ccatgctcca tctttaacac gacatcaacg gaaccgacta
     1081 cacgcccatt acttgccgga tttatcagca acacggaatc tccctcgata ttcgccacct
     1141 taccacaata ccggcgatga tcatgcccca tcataaccac atcgaagccc ggaatgcgct
     1201 gggcaacctc catcgacgca tcctcacggt actggccgga catggtacga gcctcgtttc
     1261 ccgcatgaaa gatacctacc acaacatccg gcttctcctt ctcctgaatg atcttcatcc
     1321 atttacgggc cgtctcttcc atatcggcga aataaagacc ttgccacaga gtctccggca
     1381 accatacagg aatagccgga gtaatcatcc ccagtacaac gatcttcaca ccgtcacgct
     1441 caaatacctc atagggcttt aaataggtct cccggtcgga ggtacggata atattggcac
     1501 ccaagattgg gaaatcacat tgtttgatcc aacgatcgaa aacggcatgg ccagcctcta
     1561 catcatggtt acccatattt cccgcattgt acccgatata attcatcatg gcggaagcta
     1621 tatgcgtaga gaccgtatcc atgaaattat aataatacgc cgaaggttgt ccttgcaaga
     1681 tatcgccatt atccaatagc aaaaggttat cgccatacgc ccggcgttct tcttgcacga
     1741 acgaatatac ccgtgccaga cttcctcccc actcccgctg ctcgataaaa ttatacggga
     1801 agaagtttcc atggatatca ctggtttcca ctaatttcaa ctttacttcc ttcgttgtcg
     1861 ccgacagacc gagagcgacc agcagcaata aggcaattga ataaactcgt ctcatatcag
     1921 gattttagat agattaatga cgcgaagata acgaaataac ctgttcgccc ggtttcaacg
     1981 ggatttcttt tccatcccag ataaatatac ccgtagtacc ttccggcaag accagacggg
     2041 cggttccctc acctctctca tccaatttat aagcggcggt cacgcttcca agcggatgtg
     2101 ggatcgtacc ggaaacctcc ttcagttttc ccaaagacgg agcgatccgt atcttcctaa
     2161 atccgggagc atcgctatct atccccaaca agatccggta aaactcgata ttcggactgg
     2221 ctccccaagc atggcaatca gaacgggatg gctccggcat ctctgcccat gtggtcaatc
     2281 ccaacgccat ctgatcccgc catatttgta agttatccaa gaactgatcc cctaaaccgg
     2341 aaactttcaa cgcttgattc aagtaataac ggaaatagat cgtacactgg atcaagctcg
     2401 tatccgccaa ggtttggttc atcaccttta cggcctcctc ccctttcgta accccagtca
     2461 agatcgccaa ggcgttcaca tgctgggaat agccacgatg atcctgcgta tcggcgaata
     2521 gattacgggc agcgtcccaa tatttcgggc ggatcgtctt acgcatctcg gtagcgatct
     2581 tccggtaatg atccgccatg gcagggaggc cgatcgcttg ttccatctcc accgcaaact
     2641 ccaaggtcat tatatacatc aaatcttgga gcgccgagct tccctctttc tcccgtatcg
     2701 gctcgccata atcaaaaccg gccgcccaat ccacgaagaa ccaatgagga acgtacgaca
     2761 aactataatc cggcttcaac cattgctcgt accacgacaa aacctgacgg taagcgggaa
     2821 gcaaggtctt catgtatgcc tcatccccac ggtacatcca ataatcgtgc cccatacaaa
     2881 tccaccagag agagtacgag gatataaact gatgtacgct agacggatat cggctcatcg
     2941 taatcccttc cgccaccatg gactgccgtc cttgctctat ggcattcttc accatataag
     3001 ggtctgatgt attatacatg gaaatcattg cctgtatgcg tgtatccccg aaatattgca
     3061 gttgctcgta atacgggcag tccatatacg tctcattggc gcacagacgg gcggtacgcc
     3121 atcctatctc gagcatacgg cccagctcct catgtcccgg agcggagaaa gtggtctcgt
     3181 tacggaaagg ataggcagag aaagtcccat acatatcctc gatcaccaaa ggctcggaag
     3241 ccgtcttcac tttcaactcc acatatctcc atgtacgcca ccacagggag gtgaagagac
     3301 gattatctcc cccatcagcc agtatcttat ccccgtaccc gataaactgc ttatccgtca
     3361 actcgtcccg atgtcccttg ccattcaacg catacgattt agtggtcgat tcctcttctt
     3421 gcttatagag ggcttccgaa taaccgatat ggatctcggc ctcctttcct ttgctgaagg
     3481 ctaaggagaa ataacccgtc gtcaagtaat cattatccag aagcaagcgg acctctgtat
     3541 tcgccgggat cgtcaaagct tttggccagt aaggaaatcc ttgcgggcat tcgatccctt
     3601 ccgaccggcg gagcttggcc agacgctcga tccggctgtc catcggaggt atcgggctag
     3661 gaaccagcaa ccgtcccggg taatctctcg atcctttcgt ggcaccttcc atgccccgta
     3721 cggccttctc ccatttcctg tcgtcgtaat ccggttgttc ccagccccaa ggataagcgg
     3781 aggcttccag ttcctcaccc gggccagcca cgtaataccc caatacctgc cattcggtcc
     3841 aaggagcata cgccttatta cgcaggcaga cccaagtggt atccgtattt accaccgcct
     3901 catgccccgt attgccttgc aggataaaac ccgtctgatc gtaactgatc tgggcaacag
     3961 gtttccgctc ggcataattc cagacaacgg aggccagcgt attcttccct ttcctcagat
     4021 aaggagccag atccaccgtc tcgaaactcc agttatagat atccccacgg gccgggccca
     4081 aggataccaa tttcccgttt acatataatt tataacggtt atcggcggaa acatggacga
     4141 taaaccggga aggaaccacc tccagatcga acgatttacg aaaatgatag accccatata
     4201 cattcggggc ctcacccggg taggagatcc aacgggcttt ccatcgtccc tcgaaaagag
     4261 aaggatcgat cttctcctga ttataccctt tcaggctaat ctgggaggaa agggaaaagg
     4321 cttgaaacac aaaaagcaaa aggaataaat aggttttcat acaaacacgg tattatttga
     4381 gattaacgat ccgaacaaag gtacaaaaaa agagaaagcg ccaaaagaac ttttgccttt
     4441 tgacgctttc cctcacaata taccggatgc ccggtcctcc attagaagaa tatctccggc
     4501 tccctgcgtg cgctaaagtt cttatggagc atcgccgtgt aaggagtatc gaaagtacgt
     4561 gcgccctcgg gacactcttt cacgcaggcg caacatttga tacataggtt cgggtcgcta
     4621 tacataccct cgtctgccaa ggatatcgca tgtgtaggac acacatccac gcaatactca
     4681 cattgcgtac ataaatcgtt atccgtaaca ggagcttgag gagtggaagg gcctttcacc
     4741 cgatacggga aattaccttt cacctccaag gcggacaagc attccacgca ggaaaccttc
     4801 tccagctcct cgataatctt tttcccgaat tccgtagcct gattaagatc cgactcgtcc
     4861 ggacgcccct cggcaatggg catccccttg cggctgaaag aatgctcgcc gataaacgct
     4921 ccggcagcca caggtacgaa cccctgctcc gacactaaat cacagagctc tttcaaggca
     4981 tcctcataat cccggttccc atacagtacc acggggacta ccggcgcatg gtgggcagaa
     5041 cggaacatgc gaaaacgttc catggcagtc tccgccacac ggccaccgta tacaggagcg
     5101 gctataatcg tcagctcatc atcaatatac tcttccatat ccagactctc acaagtgaca
     5161 tcagactcgg acatcgaagt ggcacccatt ccttccgcta tcgcgtaaac gatcttggcg
     5221 gacgtgtgtg tcggagaaaa ataaattaaa tgtatgttac tatatttcat gattcttatt
     5281 ttaacgcacc ctctatttta gtcattaact cagcaaattc ctcatcggta tagcctttgc
     5341 tcgtataaat gatcttcccg tcttttccga ccaaatagcc acgagggatc aagttcttgg
     5401 cgaaagcgcc gaaaatagcc cggtccttat cgggatacaa aggaaaatcg aagccttttt
     5461 tctcgttata tttctgtaga tcggcatcgg aatgctcacg cccgatcacc aagagaacga
     5521 agtccttgtt gttcttgtat ttcggccaga gggtttgttg gacagcggcc aattcttttt
     5581 ggcagggagg acaccaagtg gcgaagaaat tcacgaggat cacttttccc tttaacgaag
     5641 cggactgcaa cttactcccg ttgtcggaaa caatcgtaaa tgacggcatg gtatcaccga
     5701 ccttcacgat atcggaatta tcctcctgag ctttgcctac gaaagccaat aacgctagta
     5761 aactagccaa taaatacttc ttcataacct taatcatttc tcgtttagga ttcagcgaca
     5821 aagatacatt aaaattctca tcaaaccgca taattctaag gcttacgaaa gttctacgat
     5881 gctgtaccta cccctcgaca gctcttctaa aagttctagg gggttagatg ttaaaaaaaa
     5941 cgtacgtgaa acccggagat gtcacgtacg ctgataccat gcaaacccgg agaaagattt
     6001 accgcagact ttgcgctaag tcataaccgg ctttcaacgc ctttaggttc atattaacta
     6061 tatcctcgcc cttacgaccg aatatctgac ggattcccgc ctcgatctta tcatactcga
     6121 tcccgataaa tggggtagct gcccccaaca tcacgatatt ggcggcacgg acagaacccg
     6181 cttccttggc gatctcctcc acgtccaata cgaccttgtg agggagcttg tccaactcgg
     6241 cgttcacttt ctcgatctcc ggatagttcg ggatgttcac gaacggacgg gagtttgtca
     6301 ccagccaacc ctctttcttc aggtaaggca gataacgcaa gctctccatc ggttccaagg
     6361 agatgatcaa atcggcgtgg cccttcggga tcaagtccga ggcgatcggc tcgtcggaaa
     6421 gacgcaggtt agactgcacg tctccccccc gttgactcat accgtgtact tccgcttgct
     6481 tcatatacag accttctttt aaggcggctt ctccaataac ggcggcgata gaaaggatac
     6541 cctgtcctcc tacacctgat agtataatat ctgttttcat ttcttgcttg cttttttctt
     6601 tctggttaat gtctggatac actcacggcg ggggatcaat acggatacgc ccttgtactc
     6661 gatctcctcg cggatgatag ctttcatctc ctcatagttc tttttcaaag gaaccatcac
     6721 acggatgtga gccgggtcca caccgatacc ggcgcagata gactccagac gtcctgttcc
     6781 ggcggaatcc tgccccccgg tcatggccgt tgtctcatta tcggagataa cgatggtgat
     6841 attcgtgttc tcgttcacgc aatccagcaa accagtcata ccggaatggg taaacgtaga
     6901 atcgccgatc acggagatag ccgggaatac acccgcgtcg gaagcgccct tcgccatcgt
     6961 gatggaggcg cccatatcga tacaagaatc gatcgcacgg aaaggaggca aagctcccaa
     7021 ggtataacag ccgatatcgc caaacacctt agccgtaccg ttatactcgg cgatcacctc
     7081 gttcaaggcc tcatacatat cccggtgtcc acaaccttgg cacaatgcgg gcggacgttg
     7141 ctcaaccacc tcggggatcg cataatagct ctggatctcc ttacccaagg ctttgcctac
     7201 cgcatctggc gtaagctcac cgtcacgctg aagcgtaccg tccagacggc catgaaccgt
     7261 cacgcctttc gccaagaagc cttttaattg ctcttcaacg accggatatc cctcttccaa
     7321 caccaagatc tccttacact cgccaacgat cttctccact tgctttctcg gaagcggata
     7381 ctgggagatc ttcaatacgg gatgctcgaa accgtccgga taattctcgg aaagataatt
     7441 gaaagcgata cccgtcgtga tgatacccaa gtctttattc ggggcatcga aatacttatt
     7501 atacgcggaa ttctcggaag cttccgtgaa agcctcttga gacgccagca aactcttgaa
     7561 acgtttacga gccaatgccg ggagtaagat aaaacgttga cgaccgtctt ccggacaatt
     7621 catccggttc tccggcttca acgggctggt tacgacaccg gcacgagaat gcgccatacg
     7681 ggtcgttaca cgcagcaaga taggataccc taatttctcg gataactcga atccatgata
     7741 taccatatca taagcctctt gctggctgga tggctcaaac atcgggatca tggcgaaatt
     7801 gccataaata cggttgtctt gctcattctg ggaagagtgc atggatgggt cgtcggccgt
     7861 aaggatgatc atacctccgt tgataccgct catagcggcg ttcataaagc aatcggcggc
     7921 tacattcaaa cccacgtgct tcatgcagca aagcgcacgt ttaccggcat agcacatacc
     7981 caaagcggct tccatggcgg ttttctcatt cgcgctccag cgacaatgga tacctctttc
     8041 cttcgttacc ggagaacctt ggatatattc tgtgatttca gtagaagggg ttcccgggta
     8101 tgcgtatacc ccggagattc cagcgtctat agcggcttgc gctatggcct cgtcccccaa
     8161 aaataaatgt ttttccatgt gtatctgttt tcttaatatt gactattcac actatttagc
     8221 cgccaaaggt aatgaaaaat gttcaattta gaatgagaga cttatgattt atactagatc
     8281 cattaccgta tccggcgcct attcaactcc gcccgatacc ggttggcatt gcggttatgc
     8341 tccgccaacg tcacggcgaa attatgccgt cccgagaaat cctccttagc gcacatgtat
     8401 aagtatttat gtttcgtatg attcaatacg ctattcaagc ccttgatagt aggaatccgt
     8461 agaggaccag gaggcaggcc cgcatattta taggtattat agggagaatc tatttccaaa
     8521 tgctcaaata agatacgttg caaagaaaaa tcccccaccg cgaactttac ggtagggtct
     8581 gcctgtaaag gaataccagc atgaaggcgg ttgatataaa ggcccgccac gattggatat
     8641 tcgtccgatg ccgccgtctc ctcttctacg atagaagcca agatagatac ctcgactgga
     8701 gtaagcccga tctcctctgc ctttttcaat cgttccggtg tccagaaagc gtcatattca
     8761 cgcttcatgc gacgtataaa tttatccgcg gatatattcc aataaatctc ataggtatta
     8821 ggaatgaaga gggcatcgat cgtttccggg gtaaaaccta aagagtcgca atacacagaa
     8881 tcattcaata gacgcaggag attttccttc ccgaacatca attgatcact tatacgttcc
     8941 gccaaatctt ccttgaaacg gatattatta aaagtaaccc gggccgctac ttgatgtcct
     9001 ctccgcaaat cattcaataa ggttaaatta ctcatgccgg gcttcacggc gtatcgaccg
     9061 gtacgcatgg acgcaggata cttcaacaat ccactcaatt gcttaaagct accgatacgg
     9121 agacagttcg ccgaatccct caactgccgg caaagatcat caaaatcctt tttatcatct
     9181 atatagacat agaccgtctt atccggctta aaattcggag cccaagccaa acggtacacc
     9241 caaaagcctc caccgcctat caaaacaacg agaatcgcta tcaaggcgat aattatcggg
     9301 cgcctcgata aaatttgttt gttcaaatcc atgaataatc tattgaatat cagaataagg
     9361 cacaaaagta gtatcttttt tcgaaaaaaa tgatgtgcaa agccttgttt atttaaaatt
     9421 atagttctac ctttgcatcg caattctaag gaagaagcac agaacacaca aggaagtgtg
     9481 ggtgagtggc tgaaaccacc agtttgctaa actgacgtac tcgtaagggt accgggggtt
     9541 cgaatccccc cgcttccgca aagagccaac taataaattt attagttggt ttttttgttt
     9601 ttaagccaac cgaattaaag tgtttcatat atttgtcata tttgaactta tcgtaagtcg
     9661 atctgttatt aaaaggagat aattaaatat atacattatg acaattgctt ttatccgaac
     9721 atataataat aagcaaaact ccgaggtcca agaagctgtg atccgggaat ttgccgaatc
     9781 tcagaagata gagatcggga agtgggctaa agaggtggga aatagtcctc gtgcgaaccg
     9841 cagactggaa agtattgtca aatctttaag tcccggggat gagatacttg tgtccgatat
     9901 atcccgtgtg agccgtaaga tgatcgagat catccatatc attttgcttt gtatagagcg
     9961 aaaggtaacg cttcgtagcg taagcgacgg atatgtgttc gaggataata tcgacagtaa
    10021 gactttggcc tttaccttcg gtctggtctc cgagatcgag cgaaagctgg tctctatccg
    10081 tacgaaggaa gcccttgcct tgatcagaag taaaggtgtg gtgctgggcc gtccgaaagg
    10141 tagtcaacaa atgggacgct tggagcctta taaggaacaa atcgagaaag acttgaaaga
    10201 tccgagcttg acttacgccc agatagcgga gaaatacaat gtatcgctaa gtagcttcaa
    10261 acgctttctg aaagagtatc ttcccgataa gaaaaagaag aagaagaaat aatgattcaa
    10321 tgtgccaata tgccaatgaa ataccagaag tggataattc agatattagc atattcgcat
    10381 attggcacat tgaatcatta ttatttctct atacggatac gggcgtctac agcgaacaag
    10441 cctctatccg tagccaccaa cggatttata tccatttcct ttatctcgct ggcaaaacgc
    10501 aataaggtag agaggcgaac gataatgtcc gcatattgtt gctcgtcgat gcccttttgc
    10561 ccacgcgtac ctttaatgat cggataccct ctcaaagaac gaatcattga ataagtctca
    10621 tcatatgata acggtgccaa accataagac acatccttca atacctccac gaagattcca
    10681 cccaacccgc aaagtaccac atggccgaaa cgatcctcat atttagctcc caagaataat
    10741 tcctgtcctt tcaacatcgg ttgtaccatg atgcccgtaa cacccggcag acgcatcata
    10801 cgttcatact cgaacaataa atgctcttct ccacggatat tcaaggccac accaccgata
    10861 tcgctcttat gcacaggccc cacaaccttg gctaccaccg gatatttcac cttcttggca
    10921 aaagccagca acgcatccct atcatccgaa gcatattcct ccactaacgg gatattagcg
    10981 gcacgcaaca atgtacgcac ttcctccgga tttaaataac cgctacccgg caaccggtct
    11041 atgatacgac gaacttccgg tacatccacg ccatatagct ggatatccgt gctcatcggt
    11101 ttcggcgtat tgatcacccg tgaaagggca gtacccaatg tcacctcgtc cgagaagttc
    11161 acatggcctt tcttgacaaa gctcttcacc tccggtccgg ccgttacgat agacggtaat
    11221 atcgggaaga tcggcttctt gcactcttcc atctttttat gaagtacctc gtaggtatca
    11281 taaagtttta ccaaaccggg actaccgaag atgaccatca tcaaatccac attatcgaaa
    11341 cgattctcac agaaatcgat ggctgtagcc agatgttccg gtgtccccgt accgataata
    11401 tcaatcggat taccgacagc ggcacccgga tacagtttgg atttcaactc atcagcgata
    11461 gggccttcca aactaggaac attcaaacgc cccttggata aagcgtccgc cagcattacc
    11521 gcaggccctc cggcatgtgt cacgatcgca caattcttcc ctttcacgtc tttcaaggta
    11581 aagatactcg ccacggtagt caattcctca cggctaaaac aacgcacgat acccgcctta
    11641 cggaacaaag cctccacggc agagtccgaa ctagcgatag cgcccgtatg cgaagaggca
    11701 gctcgctttc ccgactccgt acttcccgcc ttgatagcgg cgatcttgca tcccttacgt
    11761 atcaaggaag acgcatgata caacaattta tccggttgct tgatttgctc gatatacaac
    11821 atcttgatct tggaatccaa taccggatca aagttccgat ccatatattc aaggatatcc
    11881 tctactccat tctgcttgga gttcccaacc gaccaaacag aagagaaacg cagccctttt
    11941 gtcagcgccg actcgataat gaacaaggcc gtaccgccgg agctagagat gaaatccacg
    12001 ccatcgggat ggaattccgg tatcggttgc gtaaacacgc catgataatt catattcatc
    12061 aacccgatac agttcgggcc gatcaaggag gctcccgcct cattcacgac atccagcatc
    12121 tgttgttcca agataccgcc ctcgtgtgtc tcctcgccga agccggccga gatcacgata
    12181 aaagctttta cccccttttg ccgggccagc acttccatca cctcggggca cgatttactc
    12241 ggaatcgaga tgatcgccaa ctccgtcccc gggatatcat gtacagaagg ataagacttg
    12301 acgccttgca catctgtctc cttggcgttt accacacata attctccttt atattttcca
    12361 tccaacaggt ttcgcacgat acgaccgccc ggtttatgta cgttgttgga acctcccacc
    12421 actacgatgc tttgaggatt aatcaattct cggttaatca taacattttg attagttaga
    12481 ttcaatgaat gggagcaaat atagtttttt tctccattta ttcattaaaa cccggggtat
    12541 ttatttacac tttgcactct ctgtctgcaa ccagtcacac catgcatcca tcccgtctcc
    12601 tttcgtggcg gatacctcga atatctggag atggtgattt accttcaagg cgttttcccg
    12661 aagcacttcc acttttgtat tcagataagg agccagatca atcttgttga ttacgcagat
    12721 atctgcctcc tgaaagatat gtgggtattt caacggttta tcatccccct ccgtcgtact
    12781 cacgataacg actttcttgg actctccgag atcgaacatg gccggacaga ccagattgcc
    12841 gacattctct ataaaaagga tcgctccctc cttcggattc agatgcttaa cggcatgatt
    12901 gaccatgtcg gcttccaaat gacagccggt accggtattt acctgaaaca cgggaatctc
    12961 caacgccgct atacggtcgg catcgtttga ggtttgttga tcgccttcta tcacatagat
    13021 cggtcgcttc gctttcaaac ggcggatcgt ctcttccagc aaagttgtct taccggatcc
    13081 gggcgaactc atcaagttca ggcagaacag gttcttagcc tcgaaatatc cccggtttcg
    13141 ctccgccaat aagttgttac gttgaagtat atcttgttcc agattgatta cgatcccttc
    13201 atcaggatgg tgatgatgtt catggccatg agaatgctca tgcgcatgat cgtgatggtg
    13261 atgatgctct ccgcatccgc aagttccgca catagtattt aagtttttat ttcattaata
    13321 tatcattcct ttttaataac aatcgacttc acccgaagtt ccttcccttt aaggatttta
    13381 actaaatagg agccacaatg gggacaaggg gaaaacaagg cgttcattgg gaaaatggtc
    13441 tcacagtcgc tacactgtcc ttccccctca atataatgac ggataatccg ggccttttcc
    13501 agcttgctac cttttatggc gctatccaat gcgaacgcta aggtttggat ctctacgccg
    13561 gacaaatgtc ctatctctaa ctccaactct tcgaccaccg aggctccccg gttatccgct
    13621 tgttcctcga ccagctccac gatgctacgg gctatagaca actcatgcat atctgatctc
    13681 ttttaaaagg gagtcaccga ggcgatcgtt aattgcccca cggctatccc cccatcgtta
    13741 caaggtatac gagacggaat atagacgggg accccagcca tgatgaactg tctcctcatc
    13801 gactccgtca ataatttatt ctggaaacat cctcccgaga taaccacttg tgtcgctttc
    13861 gtccgtttaa tcaacaagcg ggctttctgc acaaacaagg aagccaatgt cgtatggaaa
    13921 cgggcggata tcaagctcac cgggacctcg ttcgtcttat catgcaataa tgcctcaaac
    13981 aaagaataaa aagagatttc ctctccctcc gccgagactg gatacgcata agcgttcctc
    14041 tctcccatcg ccgcctgctc caataagacc ggagcctccg cttggtggct ggagacatcg
    14101 caaattccca ataaagaagc taccgcatca aacagccggc cagcgctgga tgtatagggt
    14161 gtattcacac ctttctccat cattcgttca agcatagcga tcctttccgt gcctatgcgt
    14221 tccacgaaat cggccggata aggaataccc gacggttcgt ccttgaaata atgccacaaa
    14281 taggcgacaa ccattcgcca tggctcctca gccgccttgt cgcctcccgg taacgggaca
    14341 tactcaaaat gggaaaggcg acggtatttc gctcggtcac aaaagaagaa ctcgcctccc
    14401 caaaccttac catcatcacc cagacctgtc ccatccatca cgatagcgag aaccggctca
    14461 ttcaatccat gctccaacat acaagcagcg gcatgagcat gatgatgttg tacctttaat
    14521 aaaggtaagg aaagagattt cgagatacgt tccgcctctt ggctggaaag ataatccgga
    14581 tgcaggtcac aaaccaatcg ctggggattg aaacgaaaca aatgacgaaa ctgctccata
    14641 gattccgtat agaaccggaa agtctcccag ttctttaagt cgccaatata ttgactttgc
    14701 aggatcgtct ctcctttccc caaagcgaac gtgttcactt tctccgcacc gaaagccatg
    14761 atcccctcca catttgtatc cgtgaaaaag ggttccggca catagccccg ggaacgacgg
    14821 atcaagcaag gttgtcctcc gcagacctgc aatacagaat catctacccg gttatggatc
    14881 gggcgattat gatgcaagag gatcgctacc tttcccgcta attgcgcctc cgcatcctcc
    14941 ggggtgatcg ctatcggcaa atcgcttaga ttcccgctgg tcattaccaa cgcaggtatc
    15001 cctgtacgag caaaccaatc gtaatgaatc ggcatataag acaacataca tcctagcgta
    15061 tgcatgcccg gattgattcc ggaagctaac cggctccgtt gcctcagcag tacgatcgga
    15121 cggcgccaag aaactaagca tcgctcctcc atcggctccg ttactgtata gacttgcaga
    15181 tgttccagat cacggaacat aacagcgaat ggtttggtat cccgctgctt tatctctcgc
    15241 agacgggcaa ccgctctctc gttcgaggca tcacaaatca aatgatagcc tccgattcct
    15301 ttagccgcaa taacctctcc accaagcaat aagcgagagg taagtttcaa taaggtctca
    15361 taatagatat aagtctcctc gttataagtc gcgtaataag tcgggccaca atgattgcaa
    15421 gcgaccggtt gggcatggaa acggcgatcg ataacattcg tatattcttt ctcacaatcg
    15481 ggacacataa ggaaaccgcc catcgttgtc tgcgaacggt cgtaaggaag gtcccggata
    15541 atagagaagc gagggccaca atgcgtacaa ttaataaaag gatatccgat tcgatggggt
    15601 tgagtagtcc ggtctcgcat acaatccgca caaacagcga tatccgggga gacctgcgtg
    15661 acctcatccg attctgaatg gctaggcgta atcgtaaaat cgtcaaaatc atcttcatcc
    15721 atttccgtag atgtatagga gatccgatgg atataagcga cacgaggatg ctcggtccgt
    15781 atacgactta tcagcaaatc ccgatcatcc ggagtagcgg caaccaagat acgtactcca
    15841 ttattcatat tctccacaca acctttcatc cccagatctt tagcgatccg gtagataaaa
    15901 gggcgaaaac caaccccttg aaccaagcct tgaataatca acgcatatac tttattcttc
    15961 gccatagcac aaatatagga agaattcgtg agattcaggc agattttggt ggaataaagt
    16021 aagtgattgg aggctaaagg aattcggtgt tgaatg
//
