LOCUS       gnlProkkaJMJJBEBA_30   10785 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMJJBEBA_30.
ACCESSION   gnlProkkaJMJJBEBA_30
VERSION     gnlProkkaJMJJBEBA_30
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:09:40
            Original ID  :: gnl|Prokka|JMJJBEBA_30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10785
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1437)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_1"
                     /sec_met_domain="Polysacc_synt (E-value: 2e-29, bitscore:
                     94.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKIIHNVLAKGGLTIFNLILPLAVMPYIYRVLDPHDLGMIEYA
                     TAIVTYFSIFGMLGIYNYGLREMSSIRNNLNSCAFLYRQLFTIGVLSNIFSATCLLLLS
                     FFMDKLVKDIVYIQLLLIVSQIFYVEWVNEAFERYSFITLKTILVRGLGYLSIFGLVTS
                     SNDYKTYVWILSITVFINYFISYLYVKKKLPIESVQVDWNFIKKIIFALFLILLLNNTN
                     LLYTLLDRFMLGLKSDIYVAYYGVGQKLSDMLKAFLTIVVVVTIPRMSLQLNQNKERYL
                     ENINHLISFLFLLTLPIASLFFCLSKEIVILFAGENYLEAIPSLKIFAIRIVVIVLEAV
                     LYNQIIFLYRREKDLLKLNALCGCLNLGLNGVLYSFLNPFLAILTTLVSELVFQILCIY
                     YIRTKIGLYITYAKKSHLLYLLLSILFPLWIYVIHLFFTSAFVVIFFSCFLSLITYIIG
                     LYLFKDKMFLLACEKIKDSIC"
     protocluster    1..10785
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1497:5785]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1498..5785
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10785
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10785
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1498..2208)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.1e-16, bitscore:
                     52.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAVIMAAGMGTRFGKYTEQIPKGFVEVCGKPMIERSIETLIS
                     CGIERIVIGTGYKHEVYDFLKKKYPMIETCFSPLYAETNSMYTLYNTQGLIGSDDFLLL
                     ESDLVFETKAITELMNCGKPDVMLATPITKFQDQYYVEFDTKHHLTACSTQKENLNVKG
                     ELVGIHKISSTFFKEMCKDYGRILSEQPKLGYEYELLRISMSTLPLFVLVVEGLKWYEI
                     DDLMDLAYAEIFFK"
     CDS             complement(2221..3339)
                     /NRPS_PKS="Domain: Aminotran_5 (31-334). E-value: 3.5e-31.
                     Score: 100.3. Matches aSDomain:
                     nrpspksdomains_ctg30_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.4; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.6e-07, bitscore:
                     20.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.6e-29, bitscore:
                     93.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIKRNILLNPGPATTTDTVKMAQVVPDICPREKEFVGMMKTLRT
                     NLLKVAHGIPGKHTAVLFCGSGTINIDVCLNSLLPKDKKVLIINNGAYSDRAVEVCRYY
                     GLSHINLRFSVYERPDLHEIESILKKDSDIFLVYTTHHETGTGLLNPIREIGALAHRYG
                     CVFITDTTSSLGMIPFDIEKDNVDFCMASAQKGLQSMTGLSFIVGNEEIICKSKEYPKR
                     SYYCNLYMQYEYFEKTGEMHFTPPVQTIYATCQALKEYFEEGEENKFARHRRVFDAIHS
                     GIEELGFKYVIDKQWQSGLVVSVLYPNHPNWNFDKVHNYCYERGFTIYPGKITTTNTFR
                     LCALGAIDESDIKSFFSVLKDALEHFNINVFY"
     aSDomain        complement(2338..3246)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg30_3_Aminotran_5.1"
                     /evalue="3.50E-31"
                     /label="ctg30_3_Aminotran_5.1"
                     /locus_tag="ctg30_3"
                     /protein_end="334"
                     /protein_start="31"
                     /score="100.3"
                     /tool="antismash"
                     /translation="REKEFVGMMKTLRTNLLKVAHGIPGKHTAVLFCGSGTINIDVCLN
                     SLLPKDKKVLIINNGAYSDRAVEVCRYYGLSHINLRFSVYERPDLHEIESILKKDSDIF
                     LVYTTHHETGTGLLNPIREIGALAHRYGCVFITDTTSSLGMIPFDIEKDNVDFCMASAQ
                     KGLQSMTGLSFIVGNEEIICKSKEYPKRSYYCNLYMQYEYFEKTGEMHFTPPVQTIYAT
                     CQALKEYFEEGEENKFARHRRVFDAIHSGIEELGFKYVIDKQWQSGLVVSVLYPNHPNW
                     NFDKVHNYCYERGFTIYPGKIT"
     CDS             complement(3344..4117)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.8;
                     E-value: 4.3e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-21, bitscore:
                     68.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDLLNAMQIPFVILNAEEDKALRQIHDIIISAKDKSIPHAIII
                     RKNIFGKYKLLNEQKNDCPLSREEALKLVVDYLEATDLVVSTTGKLSRELFEYREAEGE
                     GHECDFLTVGSMGHSSSIALGIALANSERRVFCLDGDGAFIMHMGAIGNIGYLSPKNYF
                     HILFNNGSHESVGGQPTIGFQLDIPAIAKACGYRTVFSLTTKDEIKEILQQTKIMEGPV
                     LIELKVKVASRDDLGRPTTTPLENKFHFMEFLKNK"
     CDS             complement(4484..5785)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 220.3;
                     E-value: 5.2e-67)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg30_5"
                     /sec_met_domain="CTP_transf_like (E-value: 4.3e-12,
                     bitscore: 37.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-121, bitscore:
                     396.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.7e-65, bitscore:
                     209.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQIYIGMTADIMHPGLINIINEATKFGDVIVGLLTDKAIAEHK
                     RLPYLTYEQRKKIVENIKGVSKVVPQEEWSYINNLKRLKPDYIIHGDDWKTGVLCEIRE
                     QVYDVMNKQGGTVIEIPYTQGINSSSLNRDIKSIGTTPDVRMKTLRRLINAKSIVRILE
                     AHDGLCGLIIENLEIQKGDRLEVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKIGLKKNSLFGTDAIQTQDT
                     IEGFCNKIKAGKEAQVTNDFMIIARIESFIAGKSMCDALERAYAYVEAGADGIMIHSKN
                     KSGEDIKEFCITFRQKYAHVPIVVVPTTYDHIYESELHTWGVNVVIYANHMLRAAYPAM
                     LQVAKTILENERAKEVRPLCMPIKEILELIPGTK"
     CDS             complement(5865..7016)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_6"
                     /sec_met_domain="Epimerase_2 (E-value: 5.7e-124, bitscore:
                     404.9, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIMLVFGTRPEAIKMAPLVKEFQKYPEEFKTIVCVTGQHREML
                     DQVLHIFEIIPDYDLNIMKPGQDLYDVTARVLIGMRDVLKEVQPDVVLVHGDTTTSTAS
                     ALAAFYQQIPVGHVEAGLRTHNIYSPWPEEMNRVITGRIASYHFSPTPLSRQNLLDEGV
                     RESAITVTGNTVIDALYMVVDKIKSDKRLDEELKGILKTAGYDINRLLDGKKLVLITGH
                     RRENFGDGFVSMCRAIQTLTKKYPNVDFVYPMHLNPNVRKPIYEVFGEDLSNLGNMFFI
                     EPLEYLSFVYLMEKSTIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALEAGTVKLVGT
                     NYDKIVKEVSALLDNKAHYEEMSKAVNPYGDGTACVRIVNILE"
     CDS             complement(7032..8237)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 385.1;
                     E-value: 6.1e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg30_7"
                     /transl_table=11
                     /translation="MKACFMGLGYIGLPTAIIAAKHGIQIIGVDINPKVVEMTNQGKLH
                     IIEPGMQELLQEVVTTGQLKASTTPEVSDAYFMVVPTPFKGNHEPDISYVEAATRAVIP
                     LLKEGDLYVIESTSPVGTTDKMCDLIFGLRPELRDKIYIAYCPERVLPGNVIYELVHND
                     RVIGGLNEASTDRATEFYSKFVRGTLHRTNCKTAEMCKLTENSSRDVQIAFANELSLIC
                     DKAGINVWELINLANKHPRVNILQPGCGVGGHCIAVDPYFITAEFPMESKIISTAREIN
                     NYKAFWCAEKVQNAMLKFELEYHRKPTIAMMGLAFKPDIDDLREAPAKYITTKVMQSCN
                     NADILVVEPNVQEHNVFKLTDYKEAYEKADIVVFLVAHSVFKSLPYNDRKVILDFCGIY
                     KK"
     CDS             complement(8815..9348)
                     /locus_tag="ctg30_8"
                     /transl_table=11
                     /translation="MTEQQKYWFAARTRDKQEFTVRKSLDRLKSEEHLDLDYYLPTRFV
                     ISQLKYRRKRSEVPVIRNLVFVHSTKQTACDISNIYNVPLFYMKDLATHSMLVVPDKQM
                     EDFMFVMDLNPDGVSLDSEILTVGHKVKVIKGELSGIEGEVAIEANKTYVVIRIKDLLT
                     ASIKVPKSYLKIIG"
     CDS             9991..10224
                     /locus_tag="ctg30_9"
                     /transl_table=11
                     /translation="MKQSFNDHKQGCSWPLGVTNSKAFTDEVRSPRLLRTRCKRIVQQL
                     KRHQTPLFIVGQTRKCRKTTLTDLCNPRAVLY"
ORIGIN
        1 gcatatacta tctttaattt tttcacatgc taataaaaac attttatctt taaataaata
       61 cagtcctatt atatatgtaa taagagataa aaaacaagaa aaaaatatga ctacaaaagc
      121 cgatgtgaaa aacaaatgaa ttacataaat ccataaaggg aataatatag ataacaataa
      181 atataacaaa tgcgatttct ttgcataagt aatatacaat cctatttttg ttcttatata
      241 atatatacac aatatctgaa aaacaagttc acttaccaat gttgtcaata ttgccagaaa
      301 gggattcaag aatgaatata aaacaccatt taaccctaaa ttaagacatc cacataaagc
      361 atttaacttg agtaaatctt tctcacgacg atataaaaat attatttgat tatacaaaac
      421 agcttccaag acaataacca caattcgtat tgcaaatatc tttaaagatg gaatagcctc
      481 taaataattt tcaccagcaa ataatataac aatctctttt gataagcaaa aaaataaaga
      541 ggcaattggt aaagttaata aaaataaaaa acttatcaaa tgatttatat tctccaaata
      601 tctttcttta ttttgattta attgtagaga cattctaggt atagtaacaa ctactacaat
      661 tgttaaaaaa gcttttaaca tgtctgaaag cttctgcccg acaccataat atgccacata
      721 tatatcactt ttaagcccca acataaatcg gtctaataat gtataaagca aatttgtatt
      781 attcaataat aatatcaaga ataaagcaaa tattatcttt tttataaaat tccagtcaac
      841 ttgtacagat tctataggta atttcttttt tacatataaa tagctaataa aataattaat
      901 aaaaactgtg atagacaata tccaaacata tgtcttataa tcattcgatg atgttactaa
      961 tccaaatata gacaaatatc ctaggccacg taccagtatc gtcttcaatg ttatgaaaga
     1021 atatctttca aacgcctcat taacccattc tacataaaaa atctgagaaa caattagcag
     1081 taattgtata taaacaatat cttttactaa tttatccatg aaaaaagaca atagcaacag
     1141 acatgttgcc gaaaatatat ttgacagaac tccaatcgta aataattgtc tatacaagaa
     1201 agcgcatgag tttaaattgt tacgaatcga gctcatttca cgtaagccat aattatatat
     1261 tcccaacatt ccaaatattg aaaaataagt aacaatagct gtcgcatatt ctatcattcc
     1321 caaatcatga ggatccaaca ccctatatat gtaaggcata acagctaaag gaagtattaa
     1381 attaaaaatt gtcaatcccc cctttgccaa aacattatga ataattttca aacccatgtt
     1441 aaatatgaac agttatctat attcaacaaa gtaacatcta tggaccttct aaagattcta
     1501 tttaaaaaat atttcagcat aagctaaatc catcagatca tcaatttcat accatttcaa
     1561 tccctctaca actaaaacaa agagaggtaa tgtactcatt gaaatacgaa gtagttcata
     1621 ttcatatcca agtttaggct gttcagaaag aatccggcca taatctttac acatttcttt
     1681 gaaaaaagtg ctagatattt tatgaattcc taccaattca ccttttacat tcagattctc
     1741 tttttgagta gaacaagctg tcagatgatg ttttgtatca aattccacat aatattggtc
     1801 ttgaaatttt gtaataggag ttgctaacat gacatcaggt tttccacaat tcatcaattc
     1861 agtaatagcc ttcgtttcaa atactaaatc cgattctaat aataagaaat catcactacc
     1921 tataagtcct tgagtattat aaagtgtata catactatta gtttcagcat aaagaggact
     1981 aaagcaagtt tcaatcatag gatatttctt ttttagaaaa tcataaactt cgtgtttata
     2041 tcctgtgcca attacaatac gttctattcc acaagatatt aaagtttcaa tactacgttc
     2101 tatcattggt ttaccacaca cttcaacaaa tcctttagga atctgttctg tatatttccc
     2161 aaaacgagtt cccatacctg ctgccataat tactgctgtc tttatcattc caatatggtt
     2221 ttaataaaat acattgatat taaaatgttc taaagcatct ttcaaaacag aaaaaaaaga
     2281 cttaatatcc gattcatcta ttgctcctaa tgcacaaagt cgaaaagtat ttgttgtagt
     2341 tatttttccc ggataaatgg taaaaccacg ttcataacaa taattatgta ctttgtcaaa
     2401 attccaattt ggatgattag gataaagaac agacacaacc agccctgatt gccattgctt
     2461 atcaataaca tatttaaaac ctaattcttc tatgccagaa tgaatcgcat caaacaccct
     2521 tcgatgtcgt gcaaatttat tctcttcgcc ctcttcaaaa tactctttca aggcttggca
     2581 agtagcatag attgtctgaa caggaggagt aaaatgcatt tcacccgttt tctcaaaata
     2641 ttcatattgc atataaagat tacaataata agaacgttta ggatattctt ttgacttaca
     2701 tataatctct tcattgccaa ctataaaaga aagtcccgtc atcgattgta atcctttctg
     2761 ggcagaagcc atacaaaaat caacattatc tttctctata tcaaaaggaa tcatacctaa
     2821 ggaagaagtc gtatctgtta taaatacaca accataacgg tgagcaagtg caccaatctc
     2881 acgaatagga ttcaacaaac cagtgccagt ttcatggtga gttgtataaa ctaaaaagat
     2941 atcagaatcc ttttttaata tggattcaat ctcatgcaga tcaggacgtt catacaccga
     3001 gaatctcaaa ttaatatgag ataaaccata atatcgacaa acttccacag cacgatcact
     3061 ataagcacca ttattgataa tcagcacttt tttatcctta ggtaacaaag agttcaagca
     3121 aacatcaata ttaatagtac ctgagccaca aaacaaaaca gcagtatgtt taccaggtat
     3181 accatgggca acttttaaca aatttgttcg caatgttttc atcattccta caaactcctt
     3241 ctcacgagga caaatatcag gaacaacctg agccattttc acagtatcag tggtcgtagc
     3301 aggccctgga ttcaacaaaa tatttctttt aatctgcata tacttattta ttttttaaga
     3361 actccataaa atgaaactta ttttcaagag gcgtagtcgt aggccttcct aaatcatcac
     3421 gagaagcaac ttttactttc aattcgatca aaaccggtcc ttccattatc tttgtttgct
     3481 gcaaaatctc ctttatctca tcctttgtcg taagcgaaaa aacagttcga tatccacatg
     3541 cctttgcaat agccggtata tctaattgaa aacctattgt aggttgacca ccaacagatt
     3601 catgcgaacc attgttgaac agaatatgaa aatagttttt gggagacaaa tagccaatat
     3661 tgccaatagc tcccatgtgc ataataaaag cgccatcacc atctaaacag aaaactcttc
     3721 tctctgaatt agcaagtgct atacctaaag caatagaaga gctatgcccc attgaaccta
     3781 cagtaagaaa atcgcattca tgcccctctc cttctgcttc acgatattca aacaattcac
     3841 gagacaactt acctgtagta gatactacta aatctgtagc ttccaaataa tcaacaacta
     3901 attttagggc ttcttcacgg gataaaggac aatcattttt ttgttcattt agaagtttat
     3961 attttccaaa tatatttttt cgaattataa ttgcatgagg aatggattta tctttagcag
     4021 aaataataat atcatgtatc tgcctcaatg ctttatcctc ttctgcatta agaattacaa
     4081 aaggaatttg cattgcattc aacaagtcca aagtcacttc accttgtttt tcatgctgtg
     4141 gttcatcttt tactccaggc tctccacgcc aaccaatcat taaaattatc ggtaagctat
     4201 aaaccttttt atctgcaagt gaaagcaaag gatttaccgc attacctatt cccgaatttt
     4261 gcatgtaaac caaagacaaa tttcctgagg ctaaataatg tcctgctgca atactgacag
     4321 ctgtaccttc attggcagcg ataacatgtt gctccttaaa agtatgatcc gttatatacg
     4381 cacaaatatc ttttaagagc gaatctggaa ctcctgtaaa aaaatcaatt ccgtttgcta
     4441 aaagagcatg atatactttc tcaacgttta ccatataatc tatttattta gttcctggaa
     4501 taagttccaa tatttcttta ataggcatac acaaaggacg cacctctttc gcacgctcat
     4561 tctctaaaat agtttttgcc acctgcagca ttgcaggata tgcagcacga agcatatgat
     4621 tagcatagat aaccacattt accccccacg tatgcaattc actttcataa atatggtcgt
     4681 aagtagtggg aacaacaaca atagggacat gagcatattt ctgacggaaa gttatacaga
     4741 attcttttat atcttcacct gacttatttt tactatggat cattatgcca tcagcaccag
     4801 cctctacata agcatacgcg cgttcaagag catcacacat agatttaccg gctataaaac
     4861 tctcaatacg agcaattatc ataaaatcat tggtcacttg cgcttctttt cccgccttaa
     4921 ttttgttaca aaaaccttca attgtatctt gcgtttgaat tgcatcggtt ccaaaaagtg
     4981 aatttttttt caagcctatt ttatcttcta taattacagc agaaattcca tgacgttcta
     5041 aagtacgaac cgtaaacaca aaatgttcaa ttttgcctcc tgtatcgcca tcgaaaataa
     5101 taggcttagt agtacattcc aatatattat tcaaatcctg aagacgagta gttaaatcta
     5161 cagcctcaat atcaggttta cctttgctcg ttgagtctgt taagctactg gaccacatac
     5221 catcaaaaac ctccaaacgg tcaccttttt gaatttccag gttttcgata attaagccac
     5281 ataagccatc atgagcttcc aatatacgca ctatagactt ggcatttatc aaacgacgaa
     5341 gagtcttcat tcgcacatca ggagtagtac caatagactt aatatctcta tttaatgaag
     5401 aagaatttat cccttgtgta taaggtattt ctatcactgt cccaccttgt ttattcatca
     5461 catcataaac ttgttctcgg atttcacaca gaactcccgt cttccaatca tcgccatgaa
     5521 ttatataatc tggtttcaaa cgtttcaaat tattgatata gctccactct tcttgaggaa
     5581 caactttaga aacccctttg atattctcaa caattttttt acgctgttca taagtcaaat
     5641 aaggtaaacg tttgtgttca gcaatagctt tatctgttag aagccctact attacatcac
     5701 caaattttgt agcctcatta attatattaa tcaagccggg atgcatgata tcagcagtca
     5761 tccctatgta aatttgttta ttcattttta tctatttata caaataatac attatctctc
     5821 agacgcaaaa attcaatttc aataatattc taattagaat tatttcattc taaaatattt
     5881 acaatacgaa cacatgccgt cccgtctcca taaggattca ccgccttgct catctcctca
     5941 taatgtgcct tattatccaa tagagcagag acctccttta caattttatc ataatttgtt
     6001 cccaccaatt tcaccgttcc agcttccagc gcttccggac gttctgtcgt atcacgcatt
     6061 acaagtaccg gcttcccaag tccgggagct tcttcctgaa taccaccgct atctgtcaaa
     6121 actatagtgg atttctccat cagataaaca aaagaaagat actctaaagg ctctatgaag
     6181 aacatattcc ctaaattgga taaatcttcg ccaaatacct cataaattgg tttacgaaca
     6241 ttgggattta aatgcatcgg atagacaaaa tcaacatttg gatatttctt tgtaagagtc
     6301 tgaatagccc ggcacataga aacaaatccg tcaccgaaat tttcacgacg atgacctgtt
     6361 atcaagacta atttttttcc atctaacaag cggttgatgt cataaccggc agttttcaaa
     6421 atgcctttca gctcttcatc aagcctctta tcactcttta tcttatctac aaccatgtaa
     6481 agtgcatcta ttactgtatt accagtcact gttatagctg attcccttac accttcatcc
     6541 aacagattct gacgactcaa aggagttgga gagaaatgat aactggcaat acgccctgtt
     6601 atcactcgat tcatctcctc cggccaaggg ctatatatat tatgagttcg aagtcccgcc
     6661 tctacatgtc ccactggaat ctgctgataa aaagcagcca atgccgaagc cgtagaagtg
     6721 gttgtatcac catgaaccaa aacaacatct ggctgtacct ctttcaaaac atcacgcata
     6781 cctatcaaaa cacgagctgt cacatcatac aaatcctgtc ctggtttcat aatattcaaa
     6841 tcataatcag gaatgatttc aaatatatgc aatacctgat caagcatttc gcgatgctga
     6901 ccggtaacac atacgattgt cttgaactcc tccggatatt tctgaaattc tttcaccaga
     6961 ggagccatct ttatggcttc gggacgagtc ccgaaaacca acataatctt cttcatgcta
     7021 taagctattt attatttctt gtaaattccg caaaagtcaa gaattacttt ccgatcatta
     7081 tatggcaggg atttaaatac agaatgagca accagaaaaa cgacgatatc agccttctca
     7141 taggcttctt tataatctgt aagtttaaat acattgtgtt cctgcacatt aggttccact
     7201 actaaaatat ctgcattatt acagctttgc atcactttag tagtaatata cttggcagga
     7261 gcttcacgca aatcatcaat atcgggttta aaggccaatc ccatcatggc aatggtaggt
     7321 ttacgatgat attccaattc aaacttcaac atagcattct gcactttctc tgcacaccag
     7381 aatgctttat agttattgat ttcacgagcg gtagatatga ttttagattc cataggaaat
     7441 tcagccgtaa taaaataagg atcaaccgct atacagtgtc ctccaacacc acaaccaggt
     7501 tgaaggatat tcacacgggg atgcttgttc gccaagttaa tcaattccca gacattgatt
     7561 cctgctttat cacaaatcag agagagttca ttggcaaaag ctatctgtac atcacgggag
     7621 gagttttctg tcagtttaca catttctgcc gttttacaat tagtgcgatg gagcgttcct
     7681 cgtacaaact tactataaaa ctcagtagcc ctatctgtag aagcttcatt caaaccgcca
     7741 atgacccggt cattatgaac taactcataa atgacgttcc caggaagaac acgctccgga
     7801 caataagcaa tataaatttt atctctcaat tccggacgta atccaaatat caaatcacac
     7861 attttatcag tagtacctac cggtgatgta gattctatga catacaaatc tccctctttc
     7921 aacaaaggaa ttacggcacg ggtagcagct tccacgtaag aaatatcagg ctcatgattt
     7981 cccttaaaag gagtaggtac caccataaaa taggcatcac tcacttctgg agttgttgaa
     8041 gccttcaact gaccggtagt aacgacttct tgaagaagct cctgcatacc tggttcaatg
     8101 atatgcaact taccctgatt agtcatttct acaactttgg gattaatatc aaccccgata
     8161 atctgaattc cgtgtttagc agcaataatc gcagtaggca ggccaatata acccaacccc
     8221 ataaaacatg ctttcatatc aataaaagtt atctattttt tatgatttct ttatcacact
     8281 caaatcctat tctacttcct caaacgggta tggattctct tcgatatttt tcaattcttc
     8341 aatgatttca gtttgttcca aagtcaattc atctctattc caaccttcaa taatcgcatg
     8401 agcttcctga agcaaaactt cctcataaat ttccccataa caataagtta gtaaacggac
     8461 tttaagcaaa gaagcaggca actgctccaa aacaagacaa atccgattca ataccatttg
     8521 tttcttttgc tccttatccc catcatcata aatagtagca ttatatccca tcaaaagagc
     8581 cagacacaaa ttcgcctctt cctcaacatc ggaactttga gcagaaaaaa gagaatcgga
     8641 cttaacaagc acttccttat tcaaccggca aaaattgtcg gaatagaccg gctcaccgtc
     8701 cataccaaga tacatcagct catgagctgc atgctgaagc tcaagagcac gggaagttaa
     8761 atcattcatt attatgatat atgataaaaa tataagatta tacttattta gaagtcaccc
     8821 gattattttc agataggatt tggggacttt gatacttgcc gtcaaaaggt ctttaatacg
     8881 gataacgacg tatgttttat tggcttcgat ggcaacctca ccttcaatac cgctgagttc
     8941 gcctttgata acttttactt tatgcccaac agtaagaatt tcgctatcaa ggctgacacc
     9001 gtcagggttc aaatccatta cgaacataaa gtcctccatt tgcttatccg gtaccactag
     9061 catggaatgc gtggcaagat ccttcatata aaaaaggggg acattataaa tgttggaaat
     9121 atcgcaggct gtctgcttgg tggaatgaac aaacaccaaa ttacggatta ctggaacttc
     9181 gctacgctta cggcgatact tcaattgtga aatgacaaaa cgcgtgggaa gataatagtc
     9241 aaggtccaaa tgttcttccg atttaagtcg gtccagagat ttccggactg tgaattcctg
     9301 cttgtcacgg gtgcgggctg caaaccaata tttctgttgt tcagtcactt aggaattttc
     9361 tttcgaatga atcagctcag ttccgggtgc gcttcgcggt ttgaacgaga cattttccca
     9421 cccaaaccgt attgtacact tttgcaatga taataagcta ttaaagaaga tattagactc
     9481 ataaaagtgt ccaataaacg ttcgtttaat aaacgtctat ttttaagaaa ataagtagag
     9541 gcataaaagt taaaaaggaa cagaacttta atatgttaaa tattagacgt acaatgctgc
     9601 aattcaacat attaatataa aacagaaatc actttgggaa tatttttatt aaacattttg
     9661 ttagttcaaa aaatacggct tatctttgcg tccattaaac gaacgtttaa aaaacacctc
     9721 atcatttcca atatatcatt ctacattcca atatcttacc ctcataaatg tattattgaa
     9781 gtttcgtaaa tatacctact gataaatggg aatttatcgc acagaacgca agtgaaataa
     9841 aagcccactt ccataaccta tggagagagt gaaagcccat ggatttctat ctaaaacaca
     9901 agcattcctt tgcttttcac ccttgcttgg tctactgttg cataaggagt tagtgacgcc
     9961 taacggccat gaacaaccct gctaatggcc atgaagcaat cgtttaacga ccataagcag
    10021 ggttgttcat ggccgttagg cgtcactaac tccaaggctt ttacagatga agtacgtagc
    10081 ccgcgcctat tgcgcacaag gtgcaaacgt attgtacagc aacttaaaag acatcagact
    10141 ccactattca tagtcgggca aactcgaaaa tgcaggaaaa ctacactgac cgatttatgt
    10201 aacccacgcg cggtattata ttaaagaaca ataagttacg acaaaactca gacgttttcg
    10261 gcaggtggaa gcaaattttg cttccacctt ttcaggttgc ttccaccgca gggtaaatgc
    10321 cgatggatag ggagatgcag gaggcgggtg gaagtgtgga agcaaagcag atgcaaattt
    10381 atgtttcagc accaccactc aagttttaaa aaagatgtag tataaagaca taatatataa
    10441 taagtgttat aaatacacac tttatacccc gttactcttg caaatgtcga aaaagtccgt
    10501 acctttgcaa tgtgtttttc atagtattag atttaaggtt aacaaaggtt ggagtacagc
    10561 ggtactcctt tttttatgcc catacgtacc gtcccggttc tccaataaaa ttttcacata
    10621 aaatgcaagg caacttttta tatccattta gtttttggct atctttgcac tgcttttggc
    10681 gggcataggc acgcataaag cagcttaact aacaataaat caataattaa aaacagaaaa
    10741 ttatggcaat gcatacatgg tttgaatgta agatccgtta cgaga
//
