LOCUS       c00002_gnlPro..        13452 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JMJJBEBA_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 06:22:38
            Original ID  :: gnl|Prokka|JMJJBEBA_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13452
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13452
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3452]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3452
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13452
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13452
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..680
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_1"
                     /sec_met_domain="SucD_FumR (E-value: 1.2e-128, bitscore:
                     420.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMVCEFLGAN
                     WYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQNMLVLGII
                     VIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPVFVVLYLV
                     WLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVVFFAKSLC
                     GAC"
     CDS             717..2663
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 199.7; E-value:
                     2.8e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 8.9e-61, bitscore:
                     199.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.5e-36,
                     bitscore: 118.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNNIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMEDVVLIDGRARGIIAKNLVTGKLERFAAHA
                     VVIATGGYGNAYFLSTNAMACNCSAAMACYRKGAWFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKLEDAKKLQEGTLQGKDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDKGFGVNNTGLAVFLDFSEAINRLGKDVVAQRYGNLFDMYEEITDVSPYE
                     NPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIGECNFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLADQITVPRFSTDLPEFAAAEKAVQEKIDWMMNIKGKKSVDSIHKELGHI
                     MWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELFIPGDKEGMNVELDKAIRLYDFITMGE
                     LVAYDALNRNESCGGHFREEYQTEEGEAKRDDENYFYVACWEYQGSDEKEPVLLKEPLV
                     YEAIKVQTRNYKS"
     CDS             2697..3452
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.7e-11, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 5.4e-25, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(3591..4538)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MKVFGECFFYEYYLSIFVTATNKQIYLPMPNSSACRGKKQCAQCP
                     KAVDNAIIYASHLRGFHLPARKCEENIIIFLLKGEVLVNSKEYAGTVLHAGEFILQAIG
                     SKYEILAMTDVECVCYRFSKPEFFCEDRYNHIMKEVTPPLIFYPLTITPELQLFLESSK
                     AYLSEEKICREMLCFKRKELAFILGNYYSDYELSMLIHPLAQYTNSFHYFVLQNHAKVK
                     TVEELAQLGGYTVATFRRIFNSVFHQPVYEWMMERRKESVVYELRYTDASISEICYKYG
                     FESLPHFSNFCKKNFGASPRSLRAGNLSEVNGMS"
     CDS             complement(4603..5571)
                     /locus_tag="ctg2_5"
                     /transl_table=11
                     /translation="MKKVLFLALAAAAVMSCSESEEIENAGQKAEIKLGTVVGNTTRAT
                     VTDLPELQKVGFTVYAYNTGATTMASVATFDAMKEFMAAVKVTYSAPDWSLTGETYYWP
                     MTDNLQFFAYGNPGTGALTYNQPAASAIYPSITYTVADVAAQTDLVAAKATDATKASNA
                     SGVSLKFGHILTQINFTVKAADALTYKLKTLTISGVHNKGTYGFDDSIWKSQEGTATYA
                     HTIDDGALEVNTTGVEVNTAWMLMPQTLDTNAKINVVYDIYEKDVLLDTVTSAIDLNDT
                     QAWGEGKKIRYTLTLANKAAKVTFVPEVGPWSTADDTNVEK"
     CDS             complement(5617..6600)
                     /locus_tag="ctg2_6"
                     /transl_table=11
                     /translation="MSGMKDARHMILWLFFGLLPMLGSCDFRDMLDDYPVSGVQIKLDW
                     KGVTDKLPQTMRIIFYPKDTQGRKVESYLPAGGGEVKVPPGKYAVVAYNFNTESIQIRG
                     DESYETIEAFTGHCTGLDVHEDMVWSPDPLYVVALDEVEIRQSDVALPLDWKPEAVVDH
                     YSFDIKVEGWDRISSIICHVDGLNGSYFIGNRACHLSEVPICVDTKRENGLLWGYFSSF
                     VLLKDTKTRADSPMLLTLKIVKRDKTVQEVKVDITEVIETAPPSGGGEEEPDVGVPGSE
                     IHIEVPVPEDKVVVDDLEPGTDEGDGGIGGDVDDWDDETDVELPVN"
     CDS             complement(6597..7220)
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MGKRIFIYVFWLLLFCMMSGQVIGQNKSVESHSHTCKTVLALKNN
                     LLYDLALAPNIEVELPLGKRWSLNVEYKCPWWSDSGCNFCYQLLSGGTEARYWLGNRHT
                     RGRLSGHFLGAYAEGGTYDFQLKKEKGYRGKYYAAAGITYGYVRPLARHLAIEFSVGIG
                     YLDTEYRKYTSYGNDLVWVSSGKYHFIGPTKAKVSLVWLLTSGR"
     CDS             7670..8452
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="LLSIILLTAGCSQRPAATTKIPLTSAHRGAATIAPENTMASVDSC
                     IKYGVGNIECDVCISKDSVFYVLHDSTLDRTTNGTGAISQWLSTDIDTLDAGSWFAPRF
                     AGQRVLRLTDLLRKAKEHGLRITIDYRNGGLHQLLNLIKDEGMLENCNFTFSKEYHAKC
                     FRKMAPEVRTLQAYIKSEKDIEHVVKELHPDIAVVWIDSLTPQFVKKCREHNLQVLALV
                     LGLDDKTEENQKAVDLGVDIIATDHPEKFIMKYGQPSI"
     CDS             complement(8472..9590)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MNSDERICSIALTLCPGIGHIGAKRLIEGMGSAAEVFSRRKELPE
                     IMPGVNPGVVTALDCPAAFLRAEQEMEFVEKNRLSCLTLKDEAYPSRLRECEDAPIVLF
                     FKGNTDFNRLHVIDMVGTRRATDYGKQFCADFLRDLAVLCPDVLVVSGLAYGIDIHAHR
                     VALANHLPTIAVLAHGLDRIYPYVHRKTAIDMLAQGGLLTEFLTGTNPDKHNFVSRNRI
                     VAGMSDATIVVESAAKGGSLITAELAEGYHRDCFAVPGRVTDESSIGCNRLIRDNKAAL
                     IQSAEEFVQIMGWAVAEQPARTEGIQRNLFPELTEEEELVVRILMRQGDRHINAMVVEA
                     DIPVNRMSALLFELEMKGVVKAMVGGVYHLLT"
     CDS             complement(9602..10018)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_10"
                     /sec_met_domain="HBT (E-value: 3.1e-11, bitscore: 37.2,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 6.2e-10, bitscore: 33.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYIYELPMKVRDYECDLQGIVNNANYQHYLEHTRHEFLLSAGVS
                     FAGLHEQGVDPVVARINMAFKTPLRSGDEFVSKLYMKKEGIKYVFYQDIFRASDGKVCL
                     KGIVETVCVVNGRLSDSELFDRLFAPYLNPCESV"
     CDS             complement(10050..11342)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_11"
                     /sec_met_domain="Peptidase_U32 (E-value: 4.8e-71, bitscore:
                     232.2, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKHSISDFEIMAPVGSRESLAAAIQAGADSIYFGIENLNMRARS
                     ANTFTIDDLREIARTCDEHGMKSYLTVNTIIYDHDIPLMRTIVDAAKAAGISAVIAADV
                     AVMSYARQIGQEVHLSTQLNISNVEALRFYAQFADVVVLARELNLEQVAEIYRHIREEN
                     ICGPSGEQIRIEMFCHGALCMAVSGKCYLSLHEMNHSANRGACMQVCRRSYTVRDKETN
                     VELEVDNQYIMSPKDLKTIHFMNKMLDAGVRVFKIEGRARGPEYVRTVVECYKEAIRSY
                     LDDTFTDEKIARWDERLKTVFNRGFWDGYYLGQRLGEWTKNYGSAATERKIYVGKGIRY
                     FSNIGVAEFLVEAAEVSVGDKLLITGPTTGAEFVTLDEARVDLKPVQTVKKGQHFSMKS
                     VKIRPSDKLYKLVSVEELKKFKGLDVEKQRG"
     CDS             11412..12392
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MKIKDIDLGPRPVFLAPMEDVTDPAFRLMCKHFGADMVYTEFVSA
                     DALIRSVGKTQQKLNISDEERPVAIQIYGRDTATMVEAARIVEQAHPDTLDINFGCPVK
                     RVAGKGAGAGMLQNIPLMLEITRAVVDAVKIPVTVKTRLGWDANSKIIVDLAEQLQDCG
                     IAALTIHGRTRAQMYTGEADWTLIGEVKKNPRMHIPIIGNGDITTPQRAKECFDLYGVD
                     AIMIGRASFGRPWFFKEVKHYLETGEELPPLSSEWRLNVLRQEVEDSVNLLDERRGILH
                     VRRHLAASPLFKGIPNFRDTQIAMLRAETKEELYRIFEEIEPLLP"
     CDS             12750..12875
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="MKKKKLLKQLIVNFQHSLPAEVYPRTLVLPTDSGKIITVPD"
ORIGIN
        1 ctgtaggaag gaaagtggtg atgagcgtta ccggtatcgc ccttgtcctg tttctgacat
       61 ttcacatggc gatgaacctg gttgcattag tctcggctaa tggctacaac atggtttgtg
      121 agttcctggg agcaaactgg tacgcattgg tggctacggt aggtctggct gccttattca
      181 tcatccacat catctacgct ttctggctga ctatgcagaa ccgtaaggca cgtggtagcg
      241 aacgctatgc cgttacggaa aagcccaaga ctgtggaatg ggcttctcaa aacatgctcg
      301 tactgggtat catcgtaatc gtgggtttgg gcctgcacct ggtaaacttc tgggctaaaa
      361 tgcagcttcc cgagttgatg cacaacatgg gcatgcatgc tgacaccctc acgctggcat
      421 atgcagccaa cggtgtctat cacattcaga acaccttcag caatccggta ttcgtagtgc
      481 tttacctcgt ttggctgggc gcattgtggt tccacctcac tcacggtttc tggagctcca
      541 tgcagtcttt gggctggaac aacaaagtat ggattaaccg ttggaaatgt atctccaaca
      601 tctattctac tatcgttgtc ctctgcttcg ctctggtagt tgtcgtattc tttgcaaaat
      661 cattgtgcgg cgcttgctaa attcaaattg taaatgacta aattgtaaat tgcattatga
      721 ctaagataga ttctaaaata ccggaaggac cggtggctga gaaatggacc aattataagg
      781 ctcaccaaaa attagtaaac cctgccaaca aacgtcgtct ggacatcatc gtagtaggaa
      841 ccggacttgc cggtgccagt gctgccgcct ctctgggcga aatgggtttc agagtattca
      901 acttctgcat ccaggactct ccgcgccgtg cacactccat cgctgcacaa ggtggtatca
      961 atgctgctaa gaattaccaa aacgacggtg actctgtata ccgtctgttc tacgatacag
     1021 taaagggtgg cgactaccgt gcccgcgaag ccaacgttta ccgtctggct gaagtatcca
     1081 acaatattat cgaccaatgc gttgcacaag gtgttccttt cgcccgcgaa tacggcggta
     1141 cactggacaa ccgttctttc ggtggtgctc aggtatcccg tactttctat gccaagggtc
     1201 agaccggaca gcagctgttg ctgggtgcat actctgcatt gagccgccag gtgaacgtag
     1261 gcactgtgaa actgtatacc cgctacgaaa tggaagacgt tgtcctcatt gacggacgtg
     1321 cccgcggtat cattgcaaag aacctcgtta ccggtaaatt ggaacgtttt gccgcccacg
     1381 ctgtggtaat cgctaccggt ggttacggca atgcctactt cctttctacc aatgcaatgg
     1441 catgtaactg ctctgcagca atggcttgct accgtaaagg tgcctggttt gccaaccctg
     1501 cttacgtaca gattcacccc acttgtatcc cggttcacgg tgacaagcag tctaagctga
     1561 ctttgatgtc cgaatctctg cgtaacgatg gtcgtatctg ggttccgaag aagctggaag
     1621 atgccaagaa actgcaggaa ggtacactgc aaggaaaaga tattcccgag gaagaccgcg
     1681 actactacct ggaacgccgt tatccggcat tcggtaacct cgttccgcgt gacgttgcca
     1741 gccgcgctgc caaagaacgc tgcgacaagg gcttcggcgt gaacaacacc ggtcttgccg
     1801 tattccttga cttctccgaa gctatcaacc gtctgggtaa agatgtcgtt gcacaacgtt
     1861 acggcaacct cttcgatatg tatgaagaaa tcactgatgt cagcccatac gaaaacccga
     1921 tgatgattta tccggctatc cactatacca tgggtggtat ctgggttgac tacgaactga
     1981 tgacctccat caagggactg ttcgccatcg gtgaatgtaa cttctccgac cacggtgcaa
     2041 accgcctcgg tgcttccgcc ctgatgcaag gtctggccga tggttacttc gtattgcctt
     2101 acactatcca gaactatctg gccgaccaga ttacagttcc ccgtttctct accgacctgc
     2161 ccgaatttgc agctgcagaa aaggccgttc aggagaagat tgactggatg atgaacatca
     2221 agggtaagaa gtctgtagac tctatccaca aggaactggg ccacattatg tgggaatatg
     2281 taggtatggg acgtacggcc gaaggcttga aggaaggtct gaagaagctg aaagaagtcc
     2341 gcaaggagtt cgagaaagaa ctgttcatcc cgggcgacaa ggaaggtatg aatgtagaac
     2401 tcgacaaggc tatccgtctg tacgacttca tcactatggg cgagctggtt gcttacgatg
     2461 cactgaaccg taacgaaagc tgcggcggtc acttccgtga agaatatcag actgaagaag
     2521 gcgaagccaa gcgtgacgat gaaaactact tctacgtggc ttgctgggaa tatcagggtt
     2581 ctgacgaaaa ggaaccggta ttgctgaaag agccgctggt ttacgaagca atcaaggtac
     2641 agactcgtaa ctacaaaagc taatcgggaa gttgaacatt taaagaatta aagaaaatgg
     2701 ataaaaatat atcatttacg ctcaaggtat ggcgccagaa gggtccgaaa gcaaaaggcg
     2761 cttttgaaac ataccaaatg aaagatatcc cgggcgatac ttcattcctc gaaatgctgg
     2821 atatcttgaa cgaacagctg atttctgaag gtaaagaacc ggttgtattc gaccacgact
     2881 gccgcgaagg tatctgcggt atgtgttcgc tctacatcaa cggacacccc cacggtcctg
     2941 caaccggcgc tacgacttgc cagatttata tgcgtcgttt caacgacggc gataccatca
     3001 ctgttgaacc gtggcgctct gccggtttcc cggttatcaa ggacttgatg gtcgaccgta
     3061 cggcctacga caagattatg caggcaggcg gctacgtcag cgtacgtacc ggtgctcccc
     3121 aggatgccaa cgctatcctg attccgaagc ccatcgctga cgaggctatg gatgctgcca
     3181 gctgtatcgg ttgtggtgct tgtgtggctg cttgtaagaa cggttctgct atgctgttcg
     3241 tttctgccaa ggtgagccag ctgaacctgt tgccccaagg caaaccggaa gcattgcgcc
     3301 gtgccaaggc tatgttgagc aagatggacg aactcggttt cggtaactgt acaaacactc
     3361 gtgcgtgcga agctgaatgc ccgaagaatg tttccatcag caacattgct cgcctgaacc
     3421 gcgactttat cattgcgaaa ctgaaagact aatccggtct ttctgcaaat aatataggat
     3481 gcgcttcgga taaacctttt gagcaagctc agatttatca ctcagctttc actatatttg
     3541 attaatatca caagagactc ctctgccggg aaaccgccgg aggagttttt ttatgacatg
     3601 ccgtttactt cagataaatt gccggcacgc aagctacggg gagaagcccc gaaattcttt
     3661 ttgcagaaat tggaaaaatg aggcagcgat tcaaagccat atttatagca aatctctgat
     3721 atagaagcat ccgtataacg aagttcataa accacgcttt ccttcctccg ttccatcatc
     3781 cactcgtaca ccggttgatg aaaaacagaa ttgaatatac gccggaaagt agctactgta
     3841 tatcctccca actgggcaag ttcctctacc gtcttgactt tggcatgatt ctgcaagaca
     3901 aagtagtgga aggaattagt atactgggca agaggatgta tcagcatgga aagctcatag
     3961 tcggagtagt aatttccaag aatgaaagca agttctttcc gtttgaaaca aagcatttcc
     4021 cggcaaatct tctcctcgga caaataggcc ttggaacttt ccagaaagag ctgcaactcg
     4081 ggagtaatgg tcaaaggata gaatatcaat ggaggggtaa cctctttcat aatatggtta
     4141 taccggtcct cacagaagaa ttcaggctta ctgaaccggt aacaaacgca ttccacatcc
     4201 gtcatggcaa gtatttcgta cttggaacca atagcttgaa ggatgaactc acctgcatgc
     4261 aacacagttc ccgcatactc cttactgttg acaagcactt ctcctttcag caggaaaatt
     4321 ataatatttt cctcacactt tcgcgccggc agatggaatc ctctgaggtg ggaagcatat
     4381 attattgcat tgtccacagc cttgggacat tgagcgcatt gttttttacc tctgcaagca
     4441 gaagagttgg gcatcggcaa gtagatttgt ttgtttgttg cagtgacaaa aatagataaa
     4501 taatactcat aaaagaaaca ttccccgaaa actttcataa agaagtttcg gggaatgaat
     4561 aaaatagaag taattcagtt ttttattgcg gacagtgccg ttttattttt ccacgttcgt
     4621 atcatcagcc gtactccatg gaccaacttc aggtacaaag gttacttttg ccgccttatt
     4681 ggccagcgtc agcgtataac gtatcttttt gccttcaccc caggcttgtg tatcattcaa
     4741 gtcaatggcg gaagttacag tatcaagaag aacgtctttc tcatagatgt catagacaac
     4801 attgattttg gcattcgtat ccaacgtctg gggcatcaac atccaggctg tattcacttc
     4861 cacacccgtt gtattcactt ccaatgcacc atcgtcaatc gtatgtgcat aagtggctgt
     4921 tccttcctgt gacttccata ttgaatcatc aaaaccataa gttcctttat tgtgcacacc
     4981 ggatattgta agtgttttca gtttataagt caaagcgtcg gctgccttga cagtgaaatt
     5041 tatttgggtc agtatatggc cgaatttcaa agatacccca ctggcatttg atgccttggt
     5101 tgcatccgtc gctttcgcgg ctaccaagtc cgtttgggca gctacatccg ctaccgtata
     5161 agtaatggaa ggatatatag cactagcagc cggttgattg tacgtcaagg ccccggtacc
     5221 cggattcccg taagcaaaga actgcaagtt atccgtcatt ggccaataat atgtttcccc
     5281 agtcaaactc cagtcgggag cactataagt taccttaaca gctgccatga attccttcat
     5341 cgcatcaaaa gtcgcaacag aggccattgt tgttgctccc gtattataag catacacagt
     5401 gaaccctacc ttctgcaatt ccggcaaatc agtcactgtg gctctcgtag tgttacccac
     5461 tactgttccc aatttaatct ccgccttttg tccggcattc tctatctcct cactttccga
     5521 gcaactcatt actgctgctg cagccaaagc caaaaataaa accttcttca taattgtctg
     5581 ttattaaagt taatatattt atttgtctgt ttgctatcaa ttcaccggta gctccacatc
     5641 cgtctcatca tcccaatcgt ccacatcgcc accaatccct ccatctcctt catcggttcc
     5701 cggttccaaa tcatccacca caaccttgtc ctccggtacg ggaacctcga tatggatttc
     5761 cgacccagga acgcccacat caggttcttc ttcgcctcct cccgagggag gagctgtttc
     5821 aatcacttcc gtgatgtcta ccttcacctc ttgaaccgtt ttatctcgtt tcacaatctt
     5881 cagtgtcagc aacataggac tatccgcacg ggtcttggta tctttcagta atacaaaact
     5941 ggagaaatac ccccataaaa gcccgttttc acgctttgta tccacacata taggtacctc
     6001 gctcaaatgg caagcacggt tgcctataaa gtaacttccg ttcaagccgt ccacatggca
     6061 gatgatgctc gatattctat cccatccttc cacctttata tcaaaggaat aatggtccac
     6121 taccgcttcc ggcttccagt ccaacggaag cgccacatca ctctgcctta tttccacctc
     6181 gtccaaagcc accacataca aagggtcggg cgaccaaacc atatcttcgt gtacatccag
     6241 ccccgtacag tgtcccgtaa aagcctcaat cgtctcataa ctctcgtcgc cccgtatctg
     6301 tatactctcc gtattgaagt tataggccac caccgcatac ttccccggcg gtaccttcac
     6361 ctcaccccct ccggcaggca gataactttc aacctttctc ccctgagtat ctttcggata
     6421 gaagataatc cgcatggtct gcggcagctt atccgtcacc cctttccaat ccagtttaat
     6481 ctgtactccg ctaacgggat aatcatccag catatcgcgg aagtcacagc ttcccagcat
     6541 tggcaacagc ccgaagaaca gccagagaat catatgccgt gcatctttca taccactcat
     6601 ctccccgacg ttagaagcca caccaaagaa acttttgctt ttgtcggccc gataaagtga
     6661 tactttccac tgctgaccca aaccaagtca tttccataag aagtatattt cctgtactcc
     6721 gtatccaagt atccaatgcc cacactgaat tcaatcgcca gatgccgagc cagtggacgc
     6781 acgtatccat aagttattcc tgcagctgcg taatacttcc cccggtatcc cttctccttt
     6841 ttcaactgaa aatcataggt acctccttcg gcatatgctc ccaggaagtg tccggacaat
     6901 cttccgcgcg tatggcggtt tcccaaccag taacgcgcct ctgtccctcc cgaaaggagc
     6961 tgatagcaga aattacatcc gctgtcagac caccaagggc atttgtactc aacattcaaa
     7021 gaccacctct ttcccaatgg cagctccact tctatgttcg gagccaaggc caggtcgtaa
     7081 agcaaattat tttttaacgc cagcaccgtt ttacaagtat ggctatggga ttctaccgac
     7141 ttattctgcc ctattacctg ccccgacatc atgcaaaaaa ggagtagcca aaagacatat
     7201 ataaaaatgc gttttcccat aatttcgcgt tgtatacaaa caaaagtaga agataattac
     7261 cgaataaaaa tcactttcca tcactctttt caaaggctga aaggttctgt gaaacgattg
     7321 aaacagattt gcaacttctg ccttatccgg gacgctgtga atagattctt ctctctcaaa
     7381 aagtcaatcc gtgtgcgaaa acagtaaaat tcagtgaaag aaatacaaaa gaagtagcag
     7441 gaacattctg aaatttggaa gataacaacg ggaaccttac atttgtaatg tgattttttt
     7501 catagtatta gatttaaggt taacaaaggt tggagtacag cggtactcct ttttttatgc
     7561 ccatacgttt ctccgaatga caaaaaatag ctatcttcga tggcttttat aactgttaaa
     7621 gaagaaaaca tcaccacttg agcccattat gaaaaaaccg gtactcgcat tgctttccat
     7681 aatcctactt accgcaggat gttcccaacg gcctgctgcc accaccaaga tacccctaac
     7741 cagcgcacac cgtggtgccg ccaccatcgc tcccgaaaac acaatggcat ccgtagattc
     7801 gtgcatcaaa tacggtgtag gcaatataga atgcgatgtc tgcatcagta aggacagtgt
     7861 cttctacgta ctgcacgatt ccaccctcga ccgtaccacc aacggtaccg gtgccatctc
     7921 ccaatggctg tccaccgaca tcgacacact ggatgccggc tcttggtttg cgccccgatt
     7981 tgccggacag cgggtactac gccttaccga cctgctacgc aaggccaaag agcacggttt
     8041 aagaatcacc atcgactacc gcaacggcgg tctgcaccaa ttactgaact tgataaagga
     8101 cgaaggcatg ctggaaaact gcaacttcac cttcagcaag gagtatcatg ccaaatgctt
     8161 cagaaagatg gcacccgagg taagaaccct gcaagcctac atcaaaagtg aaaaagacat
     8221 agagcatgtc gtaaaggaac tgcatcccga catcgctgtc gtctggattg actcccttac
     8281 cccgcaattc gtaaagaaat gccgtgagca caacctgcag gtactggcac tcgtcctggg
     8341 gctggacgac aagacggaag agaaccagaa ggcggtcgac ctgggggtag acatcatagc
     8401 gacggaccat ccagaaaagt tcatcatgaa atacgggcaa ccgtccatat aaggcaagag
     8461 acctgccgcg ctcaggtcag caaatgatag acaccgccca ccattgcctt gaccactcct
     8521 ttcatctcca attcaaaaag caaggcactc atccggttga cgggtatatc cgcttccacc
     8581 accatcgcat tgatatggcg gtctccctgc cgcataagaa tacgcacaac gagctcctcc
     8641 tcttccgtca gttccggaaa gagattacgc tgaatacctt ctgtccgggc aggctgctcc
     8701 gctacggccc agcccataat ctgcacaaac tcttccgcac tctggataag ggcggccttg
     8761 ttgtcgcgta tcaaccggtt acaaccgatg gaagattcgt ccgtaacacg ccccggaacg
     8821 gcaaagcagt cacgatgata tccctctgcc aactctgcag tgataaggga acctcccttt
     8881 gcggcagact ccaccacaat ggtagcatca ctcatacccg ccacaatacg gttacggcta
     8941 acaaagttat gcttgtccgg attcgtcccg gtaaggaatt cggtcagcag tccaccttgt
     9001 gccagcatgt cgatggctgt tttccggtgg acatacggat aaatgcggtc cagtccgtga
     9061 gcaaggacag caatggtagg gagatgattt gccaaagcga cccgatgggc atggatatct
     9121 atcccgtagg ccagtccgct tactaccagc acatcgggac aaagaacggc caaatcgcgc
     9181 aggaagtcgg cacagaattg cttgccgtaa tcggtggcac gacgtgtacc taccatatcg
     9241 atgacatgca ggcggttgaa atcggtgttt cctttaaaga aaagtacaat cggcgcatct
     9301 tcacattcac gcaggcggga agggtaagcc tcatccttca acgtcaggca ggaaagacga
     9361 ttcttctcta caaactccat ctcctgctcg gcacgcagaa aggcagcggg acaatcaaga
     9421 gccgtcacta cccccggatt cacaccgggc atgatttcgg ggagctcctt ccgccgactg
     9481 aatacttcgg cagcactgcc cataccctct attaaacgct ttgccccgat atgtcctata
     9541 ccggggcaaa gtgtgagagc tatgctgcaa atccgttcgt cactgttcat tccaccacag
     9601 attacacaga ttcacacgga ttgagataag gggcaaagag acggtcgaac agttcgctat
     9661 cgcttaaccg cccgttcacc acacatacgg tttcaactat gcctttgaga cagactttgc
     9721 cgtcggaagc acggaagata tcttggtaaa agacgtactt gataccctcc ttcttcatgt
     9781 agagtttgga gacaaactcg tcaccactcc tcaggggagt cttgaaagcc atattgatac
     9841 gtgccactac cgggtctacc ccctgctcgt gcagtccggc aaagctgacg ccggcactca
     9901 acagaaactc atggcgcgta tgctccagat aatgctgata attggcatta ttgacgatgc
     9961 cttgcaggtc gcattcatag tcgcgcacct tcatgggaag ttcatagata taattcatat
    10021 ttactattgg actatttact atttgatact tagccacgtt gtttctccac atccaagcct
    10081 ttgaacttct tcagttcctc tacgctgacc agcttgtaga gtttgtcact gggacgtatt
    10141 ttcaccgatt tcatcgagaa atgctggcct ttctttacag tctgcacggg tttcaaatcg
    10201 acgcgtgcct cgtccaaagt gacgaattcg gcacccgttg tgggacccgt aatcagcaac
    10261 ttgtcgccta cgctcacttc ggctgcttct accaggaact ctgccacacc gatgtttgag
    10321 aagtagcgga tgcccttacc cacatagatt ttacgttccg tagcggcaga gccgtagttc
    10381 ttggtccatt cgcccaagcg ttgtcccaag tagtagccgt cccagaaacc acgattgaag
    10441 accgtcttca aacgttcgtc ccaccgggca atcttctcat cggtgaatgt atcgtccaga
    10501 taggaacgga tggcttcttt gtaacactcc actaccgtgc gcacgtactc gggtccgcgg
    10561 gcacgtcctt ctattttgaa aacacgaaca cctgcatcca gcatcttgtt catgaagtgg
    10621 atagttttta agtctttggg ggacatgatg tattggttgt ccacctccaa ttccacattc
    10681 gtctccttgt cgcgcaccgt ataactacgg cggcatacct gcatgcaggc accgcggttg
    10741 gcggagtggt tcatttcatg caatgagaga taacactttc cgctgactgc catgcaaagc
    10801 gcaccgtgac agaacatctc tatacgtatc tgctctccac tgggaccgca gatattctcc
    10861 tcacggatat gtcggtagat ttctgccacc tgctccaaat tcagctcacg cgccagcacc
    10921 accacatcgg caaactgtgc atagaagcgc agggcttcca cgttgctgat gttgagctgt
    10981 gtgctgaggt gtacctcctg ccctatctgc cgggcatagc tcatcactgc cacatcagcg
    11041 gcaatgactg ccgagatgcc tgccgccttt gccgcatcta caatggtacg catcagcgga
    11101 atgtcatggt cgtatataat ggtattgacg gtgaggtagc tcttcatgcc atgttcgtcg
    11161 cacgtccggg ctatttcccg caaatcgtcg atagtgaagg tatttgccga acgggcacgc
    11221 atgttcaggt tctcgatacc gaaatagatg gagtcggcac ctgcttgtat ggctgctgcg
    11281 agagattcgc gcgagcctac cggtgccatg atttcgaagt cactgattga gtgtttcatc
    11341 atttcttttt gaattagagt atgcaaaggt aggctttttt ctgtactttt gcggacaaat
    11401 ccgcttagat tatgaagatt aaagatatag acctgggccc acgccccgta ttcctcgccc
    11461 cgatggagga cgtcaccgac cctgctttcc gcctgatgtg caagcacttc ggagcagaca
    11521 tggtatatac cgagttcgtt tctgccgatg ccttgatacg ctccgtaggc aagacccagc
    11581 agaaactgaa catcagcgat gaagagcggc ccgtagccat acagatatac ggacgggaca
    11641 ccgccaccat ggtagaagcc gcccgcattg tggagcaggc acatccggac acgctggaca
    11701 tcaacttcgg ctgccccgtg aagcgcgttg ccggcaaggg tgccggtgcc ggtatgctac
    11761 agaacattcc gctgatgctg gaaatcactc gtgccgtggt agatgccgtg aagattcccg
    11821 tcaccgtgaa gacccgcctg ggctgggatg ccaacagtaa aatcatcgta gaccttgccg
    11881 agcagttgca ggactgcggc attgccgccc tcaccatcca cggccgtacc cgcgcccaga
    11941 tgtataccgg cgaggcggac tggacactta tcggcgaggt gaaaaagaac ccacgcatgc
    12001 acattcccat catcggcaac ggtgatatca ccactcccca acgggccaaa gaatgcttcg
    12061 acctctacgg tgtggacgcc atcatgatag gccgtgccag cttcggccgc ccgtggttct
    12121 ttaaggaagt gaagcattat ttggagacgg gcgaagaact ccctccgctg agttccgaat
    12181 ggcgactgaa cgtactccgc caggaagtgg aagacagcgt caacctgctg gatgaacgac
    12241 ggggcatact gcacgtgcgc cgccacctgg cagcaagccc gctcttcaaa gggattccca
    12301 atttccgcga cacccagata gccatgctgc gggcagagac gaaggaggaa ctgtaccgca
    12361 tcttcgaaga gatagaaccg ttgctgccat aggagaaaac cgcatacgat ttttaccatc
    12421 gagtccgaca tttgagcaat catcctcacg ccccttcttg aatagcttct gagagggggg
    12481 gatccagacg cagatgacac gctttgttgc catccgcata actcactgtc tgtcagcaag
    12541 aaattttgcc aaccacttgc cttgcccttg gcaaactttt gccatgccta tggcaaagtt
    12601 ttgccaacgc ggtggcaaag ccttgccaat gggaaggcaa aaccttacca acaaggaggc
    12661 aagaaaaaaa acattgtttc tttggcagaa agaaacaagt ccctatattc gtcttcccaa
    12721 gaaagaaaga atcccataaa tatgtcttta tgaaaaagaa aaaactgctc aaacagctca
    12781 tcgtaaactt ccagcattca cttccggcag aagtttatcc gcgtacattg gtattgccca
    12841 cagacagtgg aaagataatc accgtgcccg actagcggaa catcggctgc gcaaaccatc
    12901 gcttgaacat ccacgtggcc aggatataaa tgccgaaagc cgatacgaaa cccacgatag
    12961 agtctatcag gtaatgtgcc tggatataga ccgtagcccc gcacaacagc agatagaaag
    13021 gaaacaagca ggcaaacaga cgcttgctgc cacgccatgc cataatcatc agtaccgtag
    13081 acattccgac atgcgaactg ggaaaagcag ccgtggggcg ctcacccacc tgctgggaac
    13141 tctccaccag gttgtagaag aagccgtgct catagcccgg accgggaaga agttcctgat
    13201 ggtgatggaa atagtcaccg atggacggaa agataccttg cgccacatgg tcgcttccaa
    13261 tggcggggaa gtagaactgc ggcccggcaa cggggacgaa gatataaata aggtaataga
    13321 tgaagaaagc ggtgacgatg acgaacgaaa ccttctcgaa aaggtcgaaa cgataaagga
    13381 aataccacac caccaccagc agaatcatcg gataatagaa gaagtacccc atattaaacg
    13441 gctcgctcac cc
//
