LOCUS       gnlProkkaBFBBIEEH_32   10697 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BFBBIEEH_32.
ACCESSION   gnlProkkaBFBBIEEH_32
VERSION     gnlProkkaBFBBIEEH_32
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:03:57
            Original ID  :: gnl|Prokka|BFBBIEEH_32
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10697
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10697
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1409:5697]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1410..5697
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..10697
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10697
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(3..1349)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_1"
                     /sec_met_domain="Polysacc_synt (E-value: 1.7e-29, bitscore:
                     94.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKIIHNVLAKGGLTIFNLILPLAVMPYIYRVLDPHDLGMIEYA
                     TAIVTYFSIFGMLGIYNYGLREMSSIRNNLNSCAFLYRQLFTIGVLSNIFSATCLLLLS
                     FFMDKLVKDIVYIQLLLIVSQIFYVEWVNEAFERYSFITLKTILVRGLGYLSIFGLVTS
                     SNDYKTYVWILSITVFINYFISYLYVKKKLPIESVQVDWNFIKKIIFALFLILLLNNTN
                     LLYTLLDRFMLGLKSDIYVAYYGVGQKLSDMLKAFLTIVVVVTIPRMSLQLNQNKERYL
                     ENINHLISFLFLLTLPIASLFFCLSKEIVILFAGENYLEAIPSLKIFAIRIVVIVLEAV
                     LYNQIIFLYRREKDLLKLNALCGCLNLGLNGVLYSFLNPFLAILTTLVSELVFQILCIY
                     YIRTKIGLYITYAKKSHLLYLLLSILFPLWIYVIHLFFTSAFVVIFFSCF"
     CDS             complement(1410..2120)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_2"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.1e-16, bitscore:
                     52.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTAVIMAAGMGTRFGKYTEQIPKGFVEVCGKPMIERSIETLIS
                     CGIERIVIGTGYKHEVYDFLKKKYPMIETCFSPLYAETNSMYTLYNTQGLIGSDDFLLL
                     ESDLVFETKAITELMNCGKPDVMLATPITKFQDQYYVEFDTKHHLTACSTQKENLNVKG
                     ELVGIHKISSTFFKEMCKDYGRILSEQPKLGYEYELLRISMSTLPLFVLVVEGLKWYEI
                     DDLMDLAYAEIFFK"
     CDS             complement(2133..3251)
                     /NRPS_PKS="Domain: Aminotran_5 (31-334). E-value: 3.5e-31.
                     Score: 100.3. Matches aSDomain:
                     nrpspksdomains_ctg32_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 67.4; E-value:
                     1.8e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_3"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.6e-07, bitscore:
                     20.7, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 3.6e-29, bitscore:
                     93.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQIKRNILLNPGPATTTDTVKMAQVVPDICPREKEFVGMMKTLRT
                     NLLKVAHGIPGKHTAVLFCGSGTINIDVCLNSLLPKDKKVLIINNGAYSDRAVEVCRYY
                     GLSHINLRFSVYERPDLHEIESILKKDSDIFLVYTTHHETGTGLLNPIREIGALAHRYG
                     CVFITDTTSSLGMIPFDIEKDNVDFCMASAQKGLQSMTGLSFIVGNEEIICKSKEYPKR
                     SYYCNLYMQYEYFEKTGEMHFTPPVQTIYATCQALKEYFEEGEENKFARHRRVFDAIHS
                     GIEELGFKYVIDKQWQSGLVVSVLYPNHPNWNFDKVHNYCYERGFTIYPGKITTTNTFR
                     LCALGAIDESDIKSFFSVLKDALEHFNINVFY"
     aSDomain        complement(2250..3158)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg32_3_Aminotran_5.1"
                     /evalue="3.50E-31"
                     /label="ctg32_3_Aminotran_5.1"
                     /locus_tag="ctg32_3"
                     /protein_end="334"
                     /protein_start="31"
                     /score="100.3"
                     /tool="antismash"
                     /translation="REKEFVGMMKTLRTNLLKVAHGIPGKHTAVLFCGSGTINIDVCLN
                     SLLPKDKKVLIINNGAYSDRAVEVCRYYGLSHINLRFSVYERPDLHEIESILKKDSDIF
                     LVYTTHHETGTGLLNPIREIGALAHRYGCVFITDTTSSLGMIPFDIEKDNVDFCMASAQ
                     KGLQSMTGLSFIVGNEEIICKSKEYPKRSYYCNLYMQYEYFEKTGEMHFTPPVQTIYAT
                     CQALKEYFEEGEENKFARHRRVFDAIHSGIEELGFKYVIDKQWQSGLVVSVLYPNHPNW
                     NFDKVHNYCYERGFTIYPGKIT"
     CDS             complement(3256..4029)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 62.8;
                     E-value: 4.3e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-21, bitscore:
                     68.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLDLLNAMQIPFVILNAEEDKALRQIHDIIISAKDKSIPHAIII
                     RKNIFGKYKLLNEQKNDCPLSREEALKLVVDYLEATDLVVSTTGKLSRELFEYREAEGE
                     GHECDFLTVGSMGHSSSIALGIALANSERRVFCLDGDGAFIMHMGAIGNIGYLSPKNYF
                     HILFNNGSHESVGGQPTIGFQLDIPAIAKACGYRTVFSLTTKDEIKEILQQTKIMEGPV
                     LIELKVKVASRDDLGRPTTTPLENKFHFMEFLKNK"
     CDS             complement(4396..5697)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 220.3;
                     E-value: 5.2e-67)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg32_5"
                     /sec_met_domain="CTP_transf_like (E-value: 4.3e-12,
                     bitscore: 37.9, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.4e-121, bitscore:
                     396.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9.7e-65, bitscore:
                     209.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKQIYIGMTADIMHPGLINIINEATKFGDVIVGLLTDKAIAEHK
                     RLPYLTYEQRKKIVENIKGVSKVVPQEEWSYINNLKRLKPDYIIHGDDWKTGVLCEIRE
                     QVYDVMNKQGGTVIEIPYTQGINSSSLNRDIKSIGTTPDVRMKTLRRLINAKSIVRILE
                     AHDGLCGLIIENLEIQKGDRLEVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAVIIEDKIGLKKNSLFGTDAIQTQDT
                     IEGFCNKIKAGKEAQVTNDFMIIARIESFIAGKSMCDALERAYAYVEAGADGIMIHSKN
                     KSGEDIKEFCITFRQKYAHVPIVVVPTTYDHIYESELHTWGVNVVIYANHMLRAAYPAM
                     LQVAKTILENERAKEVRPLCMPIKEILELIPGTK"
     CDS             complement(5777..6928)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_6"
                     /sec_met_domain="Epimerase_2 (E-value: 5.7e-124, bitscore:
                     404.9, seeds: 187, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIMLVFGTRPEAIKMAPLVKEFQKYPEEFKTIVCVTGQHREML
                     DQVLHIFEIIPDYDLNIMKPGQDLYDVTARVLIGMRDVLKEVQPDVVLVHGDTTTSTAS
                     ALAAFYQQIPVGHVEAGLRTHNIYSPWPEEMNRVITGRIASYHFSPTPLSRQNLLDEGV
                     RESAITVTGNTVIDALYMVVDKIKSDKRLDEELKGILKTAGYDINRLLDGKKLVLITGH
                     RRENFGDGFVSMCRAIQTLTKKYPNVDFVYPMHLNPNVRKPIYEVFGEDLSNLGNMFFI
                     EPLEYLSFVYLMEKSTIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALEAGTVKLVGT
                     NYDKIVKEVSALLDNKAHYEEMSKAVNPYGDGTACVRIVNILE"
     CDS             complement(6944..8149)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 385.1;
                     E-value: 6.1e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg32_7"
                     /transl_table=11
                     /translation="MKACFMGLGYIGLPTAIIAAKHGIQIIGVDINPKVVEMTNQGKLH
                     IIEPGMQELLQEVVTTGQLKASTTPEVSDAYFMVVPTPFKGNHEPDISYVEAATRAVIP
                     LLKEGDLYVIESTSPVGTTDKMCDLIFGLRPELRDKIYIAYCPERVLPGNVIYELVHND
                     RVIGGLNEASTDRATEFYSKFVRGTLHRTNCKTAEMCKLTENSSRDVQIAFANELSLIC
                     DKAGINVWELINLANKHPRVNILQPGCGVGGHCIAVDPYFITAEFPMESKIISTAREIN
                     NYKAFWCAEKVQNAMLKFELEYHRKPTIAMMGLAFKPDIDDLREAPAKYITTKVMQSCN
                     NADILVVEPNVQEHNVFKLTDYKEAYEKADIVVFLVAHSVFKSLPYNDRKVILDFCGIY
                     KK"
     CDS             complement(8727..9068)
                     /locus_tag="ctg32_8"
                     /transl_table=11
                     /translation="MFVHSTKQTACDISNIYNVPLFYMKDLATHSMLVVPDKQMEDFMF
                     VMDLNPDGVSLDSEILTVGHKVKVIKGELSGIEGEVAIEANKTYVVIRIKDLLTASIKV
                     PKSYLKIIG"
     CDS             9897..10136
                     /locus_tag="ctg32_9"
                     /transl_table=11
                     /translation="MAMKQSFNDHKQGCSWPLGVTNSKAFTDEVRSPRLLRTRCKRIVQ
                     QLKRHQTPLFIVGQTRKCRKTTLTDLCNPRAVLY"
ORIGIN
        1 aaaaaacaag aaaaaaatat gactacaaaa gccgatgtga aaaacaaatg aattacataa
       61 atccataaag ggaataatat agataacaat aaatataaca aatgcgattt ctttgcataa
      121 gtaatataca atcctatttt tgttcttata taatatatac acaatatctg aaaaacaagt
      181 tcacttacca atgttgtcaa tattgccaga aagggattca agaatgaata taaaacacca
      241 tttaacccta aattaagaca tccacataaa gcatttaact tgagtaaatc tttctcacga
      301 cgatataaaa atattatttg attatacaaa acagcttcca agacaataac cacaattcgt
      361 attgcaaata tctttaaaga tggaatagcc tctaaataat tttcaccagc aaataatata
      421 acaatctctt ttgataagca aaaaaataaa gaggcaattg gtaaagttaa taaaaataaa
      481 aaacttatca aatgatttat attctccaaa tatctttctt tattttgatt taattgtaga
      541 gacattctag gtatagtaac aactactaca attgttaaaa aagcttttaa catgtctgaa
      601 agcttctgcc cgacaccata atatgccaca tatatatcac ttttaagccc caacataaat
      661 cggtctaata atgtataaag caaatttgta ttattcaata ataatatcaa gaataaagca
      721 aatattatct tttttataaa attccagtca acttgtacag attctatagg taatttcttt
      781 tttacatata aatagctaat aaaataatta ataaaaactg tgatagacaa tatccaaaca
      841 tatgtcttat aatcattcga tgatgttact aatccaaata tagacaaata tcctaggcca
      901 cgtaccagta tcgtcttcaa tgttatgaaa gaatatcttt caaacgcctc attaacccat
      961 tctacataaa aaatctgaga aacaattagc agtaattgta tataaacaat atcttttact
     1021 aatttatcca tgaaaaaaga caatagcaac agacatgttg ccgaaaatat atttgacaga
     1081 actccaatcg taaataattg tctatacaag aaagcgcatg agtttaaatt gttacgaatc
     1141 gagctcattt cacgtaagcc ataattatat attcccaaca ttccaaatat tgaaaaataa
     1201 gtaacaatag ctgtcgcata ttctatcatt cccaaatcat gaggatccaa caccctatat
     1261 atgtaaggca taacagctaa aggaagtatt aaattaaaaa ttgtcaatcc cccctttgcc
     1321 aaaacattat gaataatttt caaacccatg ttaaatatga acagttatct atattcaaca
     1381 aagtaacatc tatggacctt ctaaagattc tatttaaaaa atatttcagc ataagctaaa
     1441 tccatcagat catcaatttc ataccatttc aatccctcta caactaaaac aaagagaggt
     1501 aatgtactca ttgaaatacg aagtagttca tattcatatc caagtttagg ctgttcagaa
     1561 agaatccggc cataatcttt acacatttct ttgaaaaaag tgctagatat tttatgaatt
     1621 cctaccaatt caccttttac attcagattc tctttttgag tagaacaagc tgtcagatga
     1681 tgttttgtat caaattccac ataatattgg tcttgaaatt ttgtaatagg agttgctaac
     1741 atgacatcag gttttccaca attcatcaat tcagtaatag ccttcgtttc aaatactaaa
     1801 tccgattcta ataataagaa atcatcacta cctataagtc cttgagtatt ataaagtgta
     1861 tacatactat tagtttcagc ataaagagga ctaaagcaag tttcaatcat aggatatttc
     1921 ttttttagaa aatcataaac ttcgtgttta tatcctgtgc caattacaat acgttctatt
     1981 ccacaagata ttaaagtttc aatactacgt tctatcattg gtttaccaca cacttcaaca
     2041 aatcctttag gaatctgttc tgtatatttc ccaaaacgag ttcccatacc tgctgccata
     2101 attactgctg tctttatcat tccaatatgg ttttaataaa atacattgat attaaaatgt
     2161 tctaaagcat ctttcaaaac agaaaaaaaa gacttaatat ccgattcatc tattgctcct
     2221 aatgcacaaa gtcgaaaagt atttgttgta gttatttttc ccggataaat ggtaaaacca
     2281 cgttcataac aataattatg tactttgtca aaattccaat ttggatgatt aggataaaga
     2341 acagacacaa ccagccctga ttgccattgc ttatcaataa catatttaaa acctaattct
     2401 tctatgccag aatgaatcgc atcaaacacc cttcgatgtc gtgcaaattt attctcttcg
     2461 ccctcttcaa aatactcttt caaggcttgg caagtagcat agattgtctg aacaggagga
     2521 gtaaaatgca tttcacccgt tttctcaaaa tattcatatt gcatataaag attacaataa
     2581 taagaacgtt taggatattc ttttgactta catataatct cttcattgcc aactataaaa
     2641 gaaagtcccg tcatcgattg taatcctttc tgggcagaag ccatacaaaa atcaacatta
     2701 tctttctcta tatcaaaagg aatcatacct aaggaagaag tcgtatctgt tataaataca
     2761 caaccataac ggtgagcaag tgcaccaatc tcacgaatag gattcaacaa accagtgcca
     2821 gtttcatggt gagttgtata aactaaaaag atatcagaat ccttttttaa tatggattca
     2881 atctcatgca gatcaggacg ttcatacacc gagaatctca aattaatatg agataaacca
     2941 taatatcgac aaacttccac agcacgatca ctataagcac cattattgat aatcagcact
     3001 tttttatcct taggtaacaa agagttcaag caaacatcaa tattaatagt acctgagcca
     3061 caaaacaaaa cagcagtatg tttaccaggt ataccatggg caacttttaa caaatttgtt
     3121 cgcaatgttt tcatcattcc tacaaactcc ttctcacgag gacaaatatc aggaacaacc
     3181 tgagccattt tcacagtatc agtggtcgta gcaggccctg gattcaacaa aatatttctt
     3241 ttaatctgca tatacttatt tattttttaa gaactccata aaatgaaact tattttcaag
     3301 aggcgtagtc gtaggccttc ctaaatcatc acgagaagca acttttactt tcaattcgat
     3361 caaaaccggt ccttccatta tctttgtttg ctgcaaaatc tcctttatct catcctttgt
     3421 cgtaagcgaa aaaacagttc gatatccaca tgcctttgca atagccggta tatctaattg
     3481 aaaacctatt gtaggttgac caccaacaga ttcatgcgaa ccattgttga acagaatatg
     3541 aaaatagttt ttgggagaca aatagccaat attgccaata gctcccatgt gcataataaa
     3601 agcgccatca ccatctaaac agaaaactct tctctctgaa ttagcaagtg ctatacctaa
     3661 agcaatagaa gagctatgcc ccattgaacc tacagtaaga aaatcgcatt catgcccctc
     3721 tccttctgct tcacgatatt caaacaattc acgagacaac ttacctgtag tagatactac
     3781 taaatctgta gcttccaaat aatcaacaac taattttagg gcttcttcac gggataaagg
     3841 acaatcattt ttttgttcat ttagaagttt atattttcca aatatatttt ttcgaattat
     3901 aattgcatga ggaatggatt tatctttagc agaaataata atatcatgta tctgcctcaa
     3961 tgctttatcc tcttctgcat taagaattac aaaaggaatt tgcattgcat tcaacaagtc
     4021 caaagtcact tcaccttgtt tttcatgctg tggttcatct tttactccag gctctccacg
     4081 ccaaccaatc attaaaatta tcggtaagct ataaaccttt ttatctgcaa gtgaaagcaa
     4141 aggatttacc gcattaccta ttcccgaatt ttgcatgtaa accaaagaca aatttcctga
     4201 ggctaaataa tgtcctgctg caatactgac agctgtacct tcattggcag cgataacatg
     4261 ttgctcctta aaagtatgat ccgttatata cgcacaaata tcttttaaga gcgaatctgg
     4321 aactcctgta aaaaaatcaa ttccgtttgc taaaagagca tgatatactt tctcaacgtt
     4381 taccatataa tctatttatt tagttcctgg aataagttcc aatatttctt taataggcat
     4441 acacaaagga cgcacctctt tcgcacgctc attctctaaa atagtttttg ccacctgcag
     4501 cattgcagga tatgcagcac gaagcatatg attagcatag ataaccacat ttacccccca
     4561 cgtatgcaat tcactttcat aaatatggtc gtaagtagtg ggaacaacaa caatagggac
     4621 atgagcatat ttctgacgga aagttataca gaattctttt atatcttcac ctgacttatt
     4681 tttactatgg atcattatgc catcagcacc agcctctaca taagcatacg cgcgttcaag
     4741 agcatcacac atagatttac cggctataaa actctcaata cgagcaatta tcataaaatc
     4801 attggtcact tgcgcttctt ttcccgcctt aattttgtta caaaaacctt caattgtatc
     4861 ttgcgtttga attgcatcgg ttccaaaaag tgaatttttt ttcaagccta ttttatcttc
     4921 tataattaca gcagaaattc catgacgttc taaagtacga accgtaaaca caaaatgttc
     4981 aattttgcct cctgtatcgc catcgaaaat aataggctta gtagtacatt ccaatatatt
     5041 attcaaatcc tgaagacgag tagttaaatc tacagcctca atatcaggtt tacctttgct
     5101 cgttgagtct gttaagctac tggaccacat accatcaaaa acctccaaac ggtcaccttt
     5161 ttgaatttcc aggttttcga taattaagcc acataagcca tcatgagctt ccaatatacg
     5221 cactatagac ttggcattta tcaaacgacg aagagtcttc attcgcacat caggagtagt
     5281 accaatagac ttaatatctc tatttaatga agaagaattt atcccttgtg tataaggtat
     5341 ttctatcact gtcccacctt gtttattcat cacatcataa acttgttctc ggatttcaca
     5401 cagaactccc gtcttccaat catcgccatg aattatataa tctggtttca aacgtttcaa
     5461 attattgata tagctccact cttcttgagg aacaacttta gaaacccctt tgatattctc
     5521 aacaattttt ttacgctgtt cataagtcaa ataaggtaaa cgtttgtgtt cagcaatagc
     5581 tttatctgtt agaagcccta ctattacatc accaaatttt gtagcctcat taattatatt
     5641 aatcaagccg ggatgcatga tatcagcagt catccctatg taaatttgtt tattcatttt
     5701 tatctattta tacaaataat acattatctc tcagacgcaa aaattcaatt tcaataatat
     5761 tctaattaga attatttcat tctaaaatat ttacaatacg aacacatgcc gtcccgtctc
     5821 cataaggatt caccgccttg ctcatctcct cataatgtgc cttattatcc aatagagcag
     5881 agacctcctt tacaatttta tcataatttg ttcccaccaa tttcaccgtt ccagcttcca
     5941 gcgcttccgg acgttctgtc gtatcacgca ttacaagtac cggcttccca agtccgggag
     6001 cttcttcctg aataccaccg ctatctgtca aaactatagt ggatttctcc atcagataaa
     6061 caaaagaaag atactctaaa ggctctatga agaacatatt ccctaaattg gataaatctt
     6121 cgccaaatac ctcataaatt ggtttacgaa cattgggatt taaatgcatc ggatagacaa
     6181 aatcaacatt tggatatttc tttgtaagag tctgaatagc ccggcacata gaaacaaatc
     6241 cgtcaccgaa attttcacga cgatgacctg ttatcaagac taattttttt ccatctaaca
     6301 agcggttgat gtcataaccg gcagttttca aaatgccttt cagctcttca tcaagcctct
     6361 tatcactctt tatcttatct acaaccatgt aaagtgcatc tattactgta ttaccagtca
     6421 ctgttatagc tgattccctt acaccttcat ccaacagatt ctgacgactc aaaggagttg
     6481 gagagaaatg ataactggca atacgccctg ttatcactcg attcatctcc tccggccaag
     6541 ggctatatat attatgagtt cgaagtcccg cctctacatg tcccactgga atctgctgat
     6601 aaaaagcagc caatgccgaa gccgtagaag tggttgtatc accatgaacc aaaacaacat
     6661 ctggctgtac ctctttcaaa acatcacgca tacctatcaa aacacgagct gtcacatcat
     6721 acaaatcctg tcctggtttc ataatattca aatcataatc aggaatgatt tcaaatatat
     6781 gcaatacctg atcaagcatt tcgcgatgct gaccggtaac acatacgatt gtcttgaact
     6841 cctccggata tttctgaaat tctttcacca gaggagccat ctttatggct tcgggacgag
     6901 tcccgaaaac caacataatc ttcttcatgc tataagctat ttattatttc ttgtaaattc
     6961 cgcaaaagtc aagaattact ttccgatcat tatatggcag ggatttaaat acagaatgag
     7021 caaccagaaa aacgacgata tcagccttct cataggcttc tttataatct gtaagtttaa
     7081 atacattgtg ttcctgcaca ttaggttcca ctactaaaat atctgcatta ttacagcttt
     7141 gcatcacttt agtagtaata tacttggcag gagcttcacg caaatcatca atatcgggtt
     7201 taaaggccaa tcccatcatg gcaatggtag gtttacgatg atattccaat tcaaacttca
     7261 acatagcatt ctgcactttc tctgcacacc agaatgcttt atagttattg atttcacgag
     7321 cggtagatat gattttagat tccataggaa attcagccgt aataaaataa ggatcaaccg
     7381 ctatacagtg tcctccaaca ccacaaccag gttgaaggat attcacacgg ggatgcttgt
     7441 tcgccaagtt aatcaattcc cagacattga ttcctgcttt atcacaaatc agagagagtt
     7501 cattggcaaa agctatctgt acatcacggg aggagttttc tgtcagttta cacatttctg
     7561 ccgttttaca attagtgcga tggagcgttc ctcgtacaaa cttactataa aactcagtag
     7621 ccctatctgt agaagcttca ttcaaaccgc caatgacccg gtcattatga actaactcat
     7681 aaatgacgtt cccaggaaga acacgctccg gacaataagc aatataaatt ttatctctca
     7741 attccggacg taatccaaat atcaaatcac acattttatc agtagtacct accggtgatg
     7801 tagattctat gacatacaaa tctccctctt tcaacaaagg aattacggca cgggtagcag
     7861 cttccacgta agaaatatca ggctcatgat ttcccttaaa aggagtaggt accaccataa
     7921 aataggcatc actcacttct ggagttgttg aagccttcaa ctgaccggta gtaacgactt
     7981 cttgaagaag ctcctgcata cctggttcaa tgatatgcaa cttaccctga ttagtcattt
     8041 ctacaacttt gggattaata tcaaccccga taatctgaat tccgtgttta gcagcaataa
     8101 tcgcagtagg caggccaata taacccaacc ccataaaaca tgctttcata tcaataaaag
     8161 ttatctattt tttatgattt ctttatcaca ctcaaatcct attctacttc ctcaaacggg
     8221 tatggattct cttcgatatt tttcaattct tcaatgattt cagtttgttc caaagtcaat
     8281 tcatctctat tccaaccttc aataatcgca tgagcttcct gaagcaaaac ttcctcataa
     8341 atttccccat aacaataagt tagtaaacgg actttaagca aagaagcagg caactgctcc
     8401 aaaacaagac aaatccgatt caataccatt tgtttctttt gctccttatc cccatcatca
     8461 taaatagtag cattatatcc catcaaaaga gccagacaca aattcgcctc ttcctcaaca
     8521 tcggaacttt gagcagaaaa aagagaatcg gacttaacaa gcacttcctt attcaaccgg
     8581 caaaaattgt cggaatagac cggctcaccg tccataccaa gatacatcag ctcatgagct
     8641 gcatgctgaa gctcaagagc acgggaagtt aaatcattca ttattatgat atatgataaa
     8701 aatataagat tatacttatt tagaagtcac ccgattattt tcagatagga tttggggact
     8761 ttgatacttg ccgtcaaaag gtctttaata cggataacga cgtatgtttt attggcttcg
     8821 atggcaacct caccttcaat accgctgagt tcgcctttga taacttttac tttatgccca
     8881 acagtaagaa tttcgctatc aaggctgaca ccgtcagggt tcaaatccat tacgaacata
     8941 aagtcctcca tttgcttatc cggtaccact agcatggaat gcgtggcaag atccttcata
     9001 taaaaaaggg ggacattata aatgttggaa atatcgcagg ctgtctgctt ggtggaatga
     9061 acaaacacca aattacggat tactggaact tcgctacgct tacggcgata cttcaattgt
     9121 gaaatgacaa aacgcgtggg aagataatag tcaaggtcca aatgttcttc cgatttaagt
     9181 cggtccagag atttccggac tgtgaattcc tgcttgtcac gggtgcgggc tgcaaaccaa
     9241 tatttctgtt gttcagtcac ttaggaattt tctttcgaat gaatcagctc agttccgggt
     9301 gcgcttcgcg gtttgaacga gacattttcc cacccaaacc gtattgtaca cttttgcaat
     9361 gataataagc tattaaagaa gatattagac tcataaaagt gtccaataaa cgttcgttta
     9421 ataaacgtct atttttaaga aaataagtag aggcataaaa gttaaaaagg aacagaactt
     9481 taatatgtta aatattagac gtacaatgct gcaattcaac atattaatat aaaacagaaa
     9541 tcactttggg aatattttta ttaaacattt tgttagttca aaaaatacgg cttatctttg
     9601 cgtccattaa acgaacgttt aaaaaacacc tcatcatttc caatatatca ttctacattc
     9661 caatatctta ccctcataaa tgtattattg aagtttcgta aatataccta ctgataaatg
     9721 ggaatttatc gcacagaacg caagtgaaat aaaagcccac ttccataacc tatggagaga
     9781 gtgaaagccc atggatttct atctaaaaca caagcattcc tttgcttttc acccttgctt
     9841 ggtctactgt tgcataagga gttagtgacg cctaacggcc atgaacaacc ctgctaatgg
     9901 ccatgaagca atcgtttaac gaccataagc agggttgttc atggccgtta ggcgtcacta
     9961 actccaaggc ttttacagat gaagtacgta gcccgcgcct attgcgcaca aggtgcaaac
    10021 gtattgtaca gcaacttaaa agacatcaga ctccactatt catagtcggg caaactcgaa
    10081 aatgcaggaa aactacactg accgatttat gtaacccacg cgcggtatta tattaaagaa
    10141 caataagtta cgacaaaact cagacgtttt cggcaggtgg aagcaaattt tgcttccacc
    10201 ttttcaggtt gcttccaccg cagggtaaat gccgatggat agggagatgc aggaggcggg
    10261 tggaagtgtg gaagcaaagc agatgcaaat ttatgtttca gcaccaccac tcaagtttta
    10321 aaaaagatgt agtataaaga cataatatat aataagtgtt ataaatacac actttatacc
    10381 ccgttactct tgcaaatgtc gaaaaagtcc gtacctttgc aatgtgtttt tcatagtatt
    10441 agatttaagg ttaacaaagg ttggagtaca gcggtactcc tttttttatg cccatacgta
    10501 ccgtcccggt tctccaataa aattttcaca taaaatgcaa ggcaactttt tatatccatt
    10561 tagtttttgg ctatctttgc actgcttttg gcgggcatag gcacgcataa agcagcttaa
    10621 ctaacaataa atcaataatt aaaaacagaa aattatggca atgcatacat ggtttgaatg
    10681 taagatccgt tacgaga
//
