LOCUS       c00015_gnlPro..        16445 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGJGMBEN_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:13:14
            Original ID  :: gnl|Prokka|KGJGMBEN_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16445
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..120)
                     /locus_tag="ctg15_1"
                     /transl_table=11
                     /translation="LKMRIWRRLSGMVFFYGSNPSGKNRARSEERRVGKECLRL"
     protocluster    1..16445
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3052:6445](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3053..6445
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16445
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16445
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(236..625)
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MDRLNEDHSMRPIADSLYRKGKMSLQGALRQRCILRSAVMGGPME
                     LVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDCSSRELVGIIMEQVK
                     DMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             complement(1039..2400)
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="VTTTPAGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKI
                     QGFLHKNEVDETTWKLWKLLDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPD
                     KWHGLADKEVTYRKRHLDLISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDV
                     AGGAAAKPFETYHNALDMPLTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNP
                     EFTMLEAYCACGDFETMANMVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWRR
                     ADYQDLIRGVAGEDWFDISPEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNP
                     CFVTHVAKDLVPLAKLNRENPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAG
                     ETQRVDYDFIETLEYGMPSAGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             complement(2397..2843)
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="LINKVRLNGNIYNMSGAKGKSNYAYVGICRPFFNNKTSFVSIPLN
                     IVLYVVLSRLFAKRPEYWGMFRHPASEKGGGRNLRVKTGCQKCPLCLTMRSPKRKQAFR
                     IPALCPNNSRHIRLRRNPNLLPCAATSSPKSVSWELTPTAQDLT"
     CDS             3053..6445
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="PFOR_II (E-value: 9.3e-18, bitscore: 55.5,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 4.5e-65, bitscore: 210.5,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 2.6e-32, bitscore: 103.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 7.8e-12, bitscore:
                     36.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 1.7e-13, bitscore: 42.4,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.8e-10, bitscore: 31.6,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6e-06, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.8e-26, bitscore: 81.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKIAGE
                     LTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAATLE
                     SRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGTAQN
                     PDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMGSGA
                     EAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGSQGE
                     PLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDTPKN
                     HFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHTNLY
                     VQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNAANG
                     ATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQTCF
                     FKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTVNGH
                     AIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDLPEW
                     DPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQISPN
                     DCTGCTLCADVCPAKSKTDPTYKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVRTDN
                     IRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTTPWS
                     HDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRILANP
                     QKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGYGGL
                     DHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATNGKPGVKKDLGLMAMTYG
                     NVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWVDSG
                     RVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLEEAQ
                     KDVWHRWNLYQSIAGMGADKPAE"
     CDS             complement(6738..6914)
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="LKQHPCFKAFFRFFHRRGPQESGPRSSGEEGVRKQYSPGRMKCPS
                     LPWTWLAAKAAVH"
     CDS             complement(6911..7348)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             complement(7345..7494)
                     /locus_tag="ctg15_8"
                     /transl_table=11
                     /translation="MMNYSKSFILSNSFFQESRVLFSAYFTKRMLPPILISACRYGKHE
                     QIMP"
     CDS             complement(7491..7778)
                     /locus_tag="ctg15_9"
                     /transl_table=11
                     /translation="LVFRSPFRHGGQDGAQTAPQFRKSIFHARRYFRIHLSRKQAVLFH
                     RTQVRSQNFLRHRPNGFAEFSKPPGAFEQIAEDEHFPAGGNQLESSFNRA"
     CDS             complement(7875..10043)
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="LRENEIPARNMRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPAL
                     VSAGTPGDAGNLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGK
                     PRTLSSLHVWPYWEGGRIYKYKIEGSEDGKNWKMLADQSSNSIAATPEGVPFKFNPQTV
                     RYVKITFLGNSAGNEKGGHLVEIKGYGPDAALSLQAAAVKDYDRIPYNGAPGQEMLQDA
                     VRLSGWRGERAGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLIS
                     DIIGSENSCDLQAGGVRPVWVEVNIPPSAKPGVYKGKVVISAESGSPVSVPVILEVAPE
                     SLPAPAHWQVHLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLID
                     EAWNAQTYDWFPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNM
                     KIRYLDEATGKYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSKGWLGKTCIGLDERPDAM
                     VRAAKNVLDKYAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKT
                     TFYVCVHPKKPNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWP
                     AGDCYLVYPGNLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFT
                     VEKSRGDSHEEDVRKAREIIRKTTEISR"
     CDS             complement(10061..10753)
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="LRDAGDPVECARAYDAQQADELVFLDITASSDGRATMADVVRRTA
                     ACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNTAAINRPELINEGAAAFGSQCIVVAI
                     DAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAERRGAGEILLTSMDADGAKTGYDIELT
                     RAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADAVLAASIFHFGEYTVPEAKAYFASRG
                     IPVRPLAE"
     CDS             11141..12889
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLV
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEDNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLAGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             complement(12870..13154)
                     /locus_tag="ctg15_13"
                     /transl_table=11
                     /translation="VRDDEKVFFKTVSDGDNDGGLVVQFQLTQSGRISVIRHHGISHQI
                     LDLLQFFIRGGNGYYFNITGGKFCAEFLPKLAQADNGVSHNGIFRLTGF"
     CDS             complement(13181..13678)
                     /locus_tag="ctg15_14"
                     /transl_table=11
                     /translation="LHRRLIRRLFLKWRGIPSACSRRMVYNPLDNWANSIKLVSLPNRT
                     RMSWSSKTRSGEGVPMTGMRGMDRISRRPCGVWASPRRMVSRLRWCSVRKPTSRRRLPT
                     QMRGTAISTMLWFSSMGETRRNSGDSNWLASCLEATRDKLMSAYTFIWLKMCSCTGLMT
                     RA"
     CDS             complement(13697..14071)
                     /locus_tag="ctg15_15"
                     /transl_table=11
                     /translation="VRHTERITADLQRQLDWLLRPRFLWAHGAERLPDLKRYMQGIAER
                     IRRIGQQPLARELERLDLFERVYFPWHQVLKEHAGDLRWMQYGYLLEEYRLAVFAPAIS
                     VKGRVSEKRLVASFEALSSQ"
     CDS             14078..15484
                     /locus_tag="ctg15_16"
                     /transl_table=11
                     /translation="LQRRKVPDGMFRTRHQFPYIRHVMRCVKKVLAQIHFRSSELLRRA
                     RQRTAHGYLCGNVHQVFRIGRRLPSEHMKRELSFQLQRKFSAEMVKLVRLAQAHETQAP
                     FPVGFRSIQFILKDTDAHGCSFIHQSHITRPSRHIHRVFQISAAPFLHAGYGHDILRCF
                     LEPAGKFFTQAVIQFRNIRAHGKLFPFIIAHPYFRNQLRRKTVHVKKGGRAKFSRFHFH
                     KFRQFPRQRPVRFQVMPQFRKISGLLADRLEKDAQILGKGTQQAFRPLGQMTGNPPLRQ
                     PFGNIRQLVDVDAQGHAVIFRAGIILVIHGIFRSFTGDFIRKTIQQVFPPEFVHGFLWR
                     NMQSFRVFLLHTGGPPQKSPGRTAVRGNKPVKEFKNSFLTPDLVRTAQLQLYLPNLFPE
                     RFQMPDTGGFRAETTAQQAFTYHYFPRMGGIDTAIVHTPVINNAQAAAHDAFHCVNSPL
                     LPVPPRSGIV"
     CDS             15732..15989
                     /locus_tag="ctg15_17"
                     /transl_table=11
                     /translation="MAKEACRSVSSSKGEILHFSVSLTSRERSSHKLNHSIMRLKLRKF
                     FPHHFRSWFLRQRLPSRNCHAAFHNLSRDRKSLSSSFHCA"
     CDS             15986..16201
                     /locus_tag="ctg15_18"
                     /transl_table=11
                     /translation="VSLVRFLSGIRRAFTGIHDAQAGYNHQHFRQGLFMLCLQQHAGQP
                     WVNGQPRQLFAYGRELPGFVQSADLP"
ORIGIN
        1 caggcgaaga cactctttcc ctacacgacg ctcttccgat ctggcccggt tctttccgga
       61 ggggttgctc ccgtaaaaga acaccatacc tgacagcctc ctccagatcc tcattttcaa
      121 gactctccgt gccccggtct gcggaaaagc cctgtttaag gcgcaataag aacagcgcga
      181 acatcttccc gcccgcccag aaccatgctc ccgcacttcc ttcgccggaa taagcttatt
      241 taccgccctc gcagggtttc cgcatgacgg cagcccagac ggaggcatta tcctgctggg
      301 gctccagcat atccttcacc tgttccatga tgattcccac cagctccctg ctggaacaat
      361 ccctggcctt ttgaagagcc aggaaagaag gttctctcaa cagctcgctc caaacctgca
      421 agccatccga gcaggccagc accgcatctc ccggatgcaa gagcaggggc atggcgctga
      481 tgtccaccag ttccatggga ccgcccataa cggcggaacg gagaatgcaa cgctgccgga
      541 gcgcaccctg aagtgacatt ttccccttcc ggtaaaggct atccgcaatc ggcctcatgg
      601 aatggtcttc attcagccgg tccatgcgaa agctgtccgc cccgctccat aaatacaggg
      661 gggagtctcc cacgctgatc caccacagga aatggtcgcg gatgaagacg gccagcaatg
      721 tggttccgga ttcctccggt tccttctgaa tggcggacaa tgccctgttg gcagcatgca
      781 aagccgccgt taaacgttcc gggatatcct cgatgccgct ttccgcaaat accgcggcaa
      841 attcctgcgc caccacacag gaggcacaat ctccgcgaag atgccctccc atgccgtcgc
      901 acacgatgcc cagcatcccg ccggcggcgg gaagactttt aaccacgtct tcctgctcgc
      961 ggcgtttgcc aatccattgg gcggaagcgc agtccagaat atccggggtg cggggaacca
     1021 tgcggccggt ggttcggatt aactgtcctt acgtttcaac tgcgggaaga gcagcacgtc
     1081 acggatggaa gaggcccccg tcagcatcat gacgacgcgg tcgatgccga taccgatgcc
     1141 gcctgcggag ggcattccgt attccagcgt ttcaatgaaa tcatagtcca cgcgctgggt
     1201 ctccccggca gcctggtgct ccaggcgttc cttttgcacg tcgggatcgt tcaattccga
     1261 atagccgggg gaaatttcct gcccgttgat caccagttca tatacgtcca ctacgtccgg
     1321 attttcccgg ttcagcttgg ccaggggaac caggtccttg gccacgtggg taacaaagca
     1381 ggggttcatg gtcttttcct ccaccagttt ttcatacacc tgctgggaaa catccacatc
     1441 tttcatatcc gggctgattt ccactcccag ctcttcacag cgggcgcggc gcgcttcggg
     1501 ggagatgtca aaccagtctt cccccgccac gccccggatc aggtcctggt agtcggcgcg
     1561 tctccagggc cggctgaggt cgattgtgta aagaacgttg ccttccgcgt ccttgtggtc
     1621 aatctgaagg ccaccgcaga atttttccgc cagatggcag atgagctcct ccaccatatt
     1681 cgccatggtc tcaaaatcac cgcaggcgca ataggcttcc agcatggtga attccgggtt
     1741 gtggcggcgg tcaattcctt cattgcggaa gctgcggttg agttcgaaaa ttttcgtgaa
     1801 gccgcccacc atcaggcgtt tgaggaaaag ctccggggca atgcgcagcg tcaacggcat
     1861 atccagcgcg ttatggtacg tttcaaacgg cttggcggcg gccccaccgg ccacatcctg
     1921 aagcatgggg gtttccactt ccagataacc gcgttcctgg agaaagcggc ggatttccgc
     1981 aatcatgagg gagcgcgtaa cgaacaggga ggcgctttcc tcattggaaa tgaggtccag
     2041 gtggcgcttg cggtaggtca cctccttgtc cgccagcccg tgccacttgt ccggcagggg
     2101 gcggaggctt ttggaaagaa tggtcagtcc ggataccttt acggtaggtt ctccggtacg
     2161 ggtcaggaac gtggttcccc tgatgccgac ccagtccccg cggtccagga gcttccaaag
     2221 cttccaggtg gtttcatcca cctcattttt atgcaggaac ccctggattt ttccccgtac
     2281 gtccccaatg acgaaaaact gggatttgcc catgtcgcga atagccagaa ggcggccggc
     2341 gacggctacc tgtttgtctt cctggaaatc ggctttcaat ccggcgggag tggtggtcac
     2401 gtcaaatctt gcgccgtagg ggtcaattcc cagctcacgg attttggcga gcttgtcgcg
     2461 gcgcacggca ataagttcgg attccgtcgt agtcggatgt gcctgctgtt gttcggacat
     2521 agtgcgggga ttctaaaggc ttgcttccgt tttggcgagc gcattgtcag gcagagggga
     2581 catttttggc agccggtttt gacccgaagg ttcctccccc cccctttttc ggaagccgga
     2641 tgccggaaca tgccccagta ctccggccgt tttgcaaaaa gcctggacag aaccacataa
     2701 agcacgatat tcaaaggaat tgaaacaaaa ctggtcttat tattaaaaaa tggccggcaa
     2761 atccccacat acgcataatt gcttttacct ttggcaccag acatgttata aatgtttccg
     2821 ttaagacgca ccttatttat caattatata ctatccgtgc agacttatga gtgatcagac
     2881 aaccgtaact tacagcacga ttgacgctaa cgaagccgta gcttctgtag cctatcgttt
     2941 ttctgaagtc attgccattt accccattac accatcttct ccgatgggtg aatcagctga
     3001 aagctgggcc gctgtcaaca ggaagaacct gtggggcacc gttccctccg tagtggaaat
     3061 gcagagtgaa ggcggcgcgg caggcaccgt tcacggcgcc ctccagaccg gagcgcttgc
     3121 aactacgttc accgcatccc aggggctcct gctgatgatc ccgaacatgt tcaaaatcgc
     3181 aggggaactg actcccgccg tgttccacgt agccgcccgg tccctggctt accaggccct
     3241 ttccattttt ggcgaccaca gcgacgtgat gagcgcccgc tcctgcggat gggccatgct
     3301 gtgcggctcc tccactcagg aagctgcgga cttcgccgct atttcccacg ccgctacact
     3361 ggaatcccgc attcctttca tcaatttctt tgacgggttc cgcacgtccc acgaaatcgg
     3421 caagattgca gacatcacgg acgataccct gaacggcatg attaagcagg aatggctgga
     3481 ttccttccgg gaacgagccc tgacccctga tgctcccgtt ctgcgcggca ctgcccagaa
     3541 cccggacgtt tacttccagg gacgtgaaac ggtcaaccgt ttctatgaag ccactccggc
     3601 tattgtccag aacgccatgg acaaatttgc ggaacttacc ggccgttcct accatctggt
     3661 ggattacacc ggcgctccgg acgccgaacg cgtcattatc ctgatgggat ccggcgctga
     3721 agctgtggaa gaaacggtag aagccatgat gacccgggaa aacgccaagg taggcgtgct
     3781 gaaggtgcgc ctgttccgcc ccttccccgc cgccgaactc gtcaaggccc tccccgctac
     3841 ggtcaggaaa atcgccgtgc tggaccgcac caaggaaccc ggctcccagg gagaaccgct
     3901 ccaccaggac atcatccagg ccctcttcga cgcccaggcc aacggcacgc tgcccttcac
     3961 caacggcatg cccaaggtgg taggcggacg ctacggcctc tcctccaagg aattcacccc
     4021 cgccatggtc aagggcgtct atgacaacct ggctctggac actcccaaga atcatttcac
     4081 catcggcatc aacgacgacg tactgggcac cagcctcccg tatgatgaag attattccac
     4141 ggaagcggac gacgtgacgc gggccatgtt cttcggcctc ggttccgacg gcaccgtagg
     4201 cgccaataag gacgccatca agatcatcgg ccagcatacg aacctgtatg tgcagggcta
     4261 cttcgtgtat gactccaaga aatcgggttc ctccaccatt tcccacctgc gcttcggtcc
     4321 ccgtccgatc aaatccacat acctgatcac caaggcaaac ttcctggccc tgcaccagcc
     4381 ttccctgctg gatctgttcg acttcctgaa gaatgccgcc aacggcgcca ctttcctgat
     4441 gaacagcccg cacccggcgg acaaactctg ggacacgctg cccgcccgca tgcagcagca
     4501 gattctggac aagaacatca agctctacac gattgacgct tttgccgtgg cccgcaaaac
     4561 gggcatgggc ggccgcatca atatgattat gcagacctgc ttcttcaagc tggccagcgt
     4621 gattcccgcg gatgaagcca tcggctacat caagaaggcc attgccaaaa cctacgccaa
     4681 gaagggccag gaagtggtgg acaaaaacat cgccgccgtg gacgccacgc tggaaaacct
     4741 gcatcaggtg gacacaaccg gaaaaactgt aaacggacac gccattccgc ccgccatgtc
     4801 cccggacgct ccggactacg tacaaaacgt ccttggcaag atgatgtgcg gtgaaggcga
     4861 cagcatcccg gtcagccaaa tgcccgtgga cggcacattc ccgaacggaa cgtcccagta
     4921 cgaaaagcgc aatctggccc tggatctgcc ggaatgggat ccgaccctct gcatccagtg
     4981 cggcaagtgt accgccgtct gcccgcacgc ggttatccgc agtaaattct tctctcctga
     5041 tgctcttgca aacgctccgg aagggtttga atgcctggat gccaagcatc cggactggaa
     5101 gggagagaaa ttcgtcatcc agatttcccc gaacgactgt acgggctgta cgctctgcgc
     5161 ggatgtctgc ccggccaaga gcaagacgga cccgacgtac aaggccctga ccatggtccc
     5221 ggccgggaag attcacgaca aggaagaagc caattggaat ttcttcctga gccttccgga
     5281 cgtggaccgc accaaggtaa gaacggacaa catccgctct atgcaggtgc tgcgcccgct
     5341 gttcgaattc tccggcgcct gtgccggttg cggtgaaact ccgtatgtaa aaatgctctc
     5401 ccagctcttc ggcaaccgcc tggtggtcgc caatgctacg ggctgctcct ccatttacgg
     5461 cggcaacctg cccaccaccc cgtggtccca tgactctgaa gggcgcggcc ccgcctgggc
     5521 caactccctg tttgaagaca acgccgaatt cggccttggc ttccgcgtct ccctggacaa
     5581 gcagatggaa cacgccattg agcttcttca tgaagctgcc ggcgccgtgg gccaggaact
     5641 ggtggaccgg atactggcta atccgcagaa ggatgaagca gacatcgccc agcagcgtga
     5701 aaacattgaa gaactcaaga agaaaattgc cggcaagccg gaatacgcgc gcctcctgac
     5761 ccttgcggat aaacttgtcc gcaagagcgt gtggattctg ggcggcgacg gctgggccta
     5821 cgacatcggc tacggcggcc tggatcacat tctggccagc ggccggaacg tgaaggtgct
     5881 ggtcatggat acggaagtat actccaacac cggcggccag tgctccaaat ccaccccgcg
     5941 cgccgcagta gccaaattcg ccacgaacgg caaacccggc gtgaaaaagg atctgggcct
     6001 catggccatg acttacggca acgtgtacgt ggcctccgtc gctctcggcg ccaaggacga
     6061 acacacgctg aaagcctttg tggaagcgga agcctatgac ggcccggctc tcatcatcgc
     6121 ctactcccac tgcatctccc acggcatcaa tatggccaag ggcctgcagc agcagaaggc
     6181 atgggtggat tccggccgag tcctgcttta ccgctataat ccggacctgg ctcgccaggg
     6241 caagaatccg ctgattgtgg aaggcaaggg cccgaagggc gatctgcgcg atgtgctgct
     6301 cagcgaaaac cgcttcaaac ttctggcgaa gaccaataag gaaggattcg aaaaactcct
     6361 tgaagaagcc cagaaggatg tctggcaccg ctggaacctg taccaaagca ttgccggcat
     6421 gggtgccgac aaacctgcgg aataaggtat aggccgctta atttcaacgc ccctgtccgg
     6481 cttatccggc aggggcgttt tttactgccg gatattcatg aaaaacaaac catgaatatt
     6541 tcggggaggg gactgctttt ccgccccgcc atacagccac gcaagcaggc ttcccgcgcc
     6601 agtactttcc cttcctgaaa gccggagaat tcatccttcc cccgcagcac aaaaaagggc
     6661 gcacaccttg ctgcaaggcc gggttttaat agatcacctt atacgggtta atttccgcat
     6721 ggaggttttg aaggccttca atgaaccgca gcctttgcgg ccagccatgt ccaaggcaaa
     6781 gaggggcatt tcatgcggcc aggggaatac tgtttcctca caccttcctc cccagaggag
     6841 cgcggcccgc tttcctgcgg accgcgccgg tggaaaaacc ggaaaaaggc tttaaaacag
     6901 ggatgctgct tcaagattcc cgaaaatggt gcacaccgga ggaggaatat accattccgg
     6961 atgccgtatc cgggaagtgc accacatcag gcgtcaggcg agtgcccaca tccagataga
     7021 ccagcttctc cgtagcggat ccgttgcgga taacatgcgc tccctccggg ctggcaggga
     7081 atgcaatcgc atccccctct tttaaattct tttcaccctc aggcgtacgc acaacggcat
     7141 ggcccctgat gatgtaaaat acctcttcat tcacttcatg ataatggtag ccataggcgt
     7201 accgccccgg ctccacttcc acgaaactgg ccgcacattt tccggcatcc gcttcccgga
     7261 tgacgggctt taccgcaaag gaattaccct cccggctgat aacctgaggc tccgtctccc
     7321 tgtaattggc aatgatgatc ttgttcatgg cattatctgt tcatgcttgc cgtaacggca
     7381 ggcacttatt aaaataggcg gtaacattct ttttgtaaag taggcagaaa atagtaccct
     7441 ggattcctga aagaaactat tgcttaaaat aaatgactta ctataattca tcatgccctg
     7501 ttgaaactac tctccaactg atttcctccc gctggaaagt gctcatcctc cgcgatctgc
     7561 tcgaaggcac ccggcggttt ggagaactcc gcaaatccat tgggcctgtg acgcagaaag
     7621 ttctgactgc gaacctgcgt tctatggaaa aggacggcct gcttacgcga aaggtgtatg
     7681 cggaagtacc tccgcgcgtg gaatatactc ttacggaact ggggcgcagt ctgcgccccg
     7741 tcctggcctc catggcggaa tggggatcga aataccaaag agaaaaccgc tgatcctccc
     7801 ccctttccgg agcttaaccg aacctccgga aagacatgga aatacagcag tttccctttt
     7861 tcccgcaaga aaggtcagcg ggaaatttcc gtcgttttac ggataatttc gcgggctttc
     7921 cgcacgtctt cctcatggga atccccgcgg cttttttcca cggtaaagag cttggaaagc
     7981 tcttcatcca tgcgggctac ggcagctttc gccttaggat tttttgcggc gcgggcgcgc
     8041 aggatattga ccttttcaaa ttcctccagt ccgtcccgga gtttttcaaa ccgcagggaa
     8101 ctgagattgc cgggataaac aaggtagcag tctcccgcgg gccagttccc gaaatcggtc
     8161 ttttcaaacg gattacggtt ccaggaatta taagcccatc tcaaaaagcc gtccaaatga
     8221 ttggcggcgg caaagagggg aagccattcc gcctccgcca gcggggaaat agtgaaggtg
     8281 ttgggctttt tgggatggac acagacatag aacgtcgtct tttttccctc ctttttacgc
     8341 tgcgccagca gatcgcccgt gaccgtgcct gcatggtcaa ttacaggaga gacgtcataa
     8401 acgtcccggg tcatggccgt aggccgattg acggcggaaa cgattttgaa ttccggggca
     8461 tacttgtcca gcacattctt ggccgccctg accatagcgt ccggccgttc atccagcccg
     8521 atgcaggttt tgcccagcca gcccttgctc ttgacgtgct tgcgaaaatc cgtcaggaaa
     8581 ggcccccaga tagcttcata ggagggatcg ttcggcttaa gatccagaaa tttgtacttt
     8641 ccggtcgcct catccagata acggattttc atgttccagg gaatcatggt atagcaggat
     8701 atctgcccct tgacgcccac ctcgttcatc atgaaggaaa cccacttgtc aaaattggcg
     8761 taattccagc gcatggttcc gtttttgccc ttgacccatt caatcatggg cgggaaccag
     8821 tcataagtct gggcattcca ggcttcatca atcagggagc atgtaatggc cttttgcccg
     8881 gcatccgcca gccttttcat caccggcttc atcagtgcga aatgctccgg agaccacggt
     8941 tccacatcat gccagcgggc cacggcctgc ggatgctgcc acaagtccag atgaacttgc
     9001 caatgcgcgg gagcagggag ggattccggc gccacctcca gaattaccgg cacactgacg
     9061 ggagagccgc tttctgcgga aattaccact tttcctttgt acacgccggg tttggcagac
     9121 ggggggatat tgacctccac ccataccgga cgcacgcctc cggcttgcaa atcgcagctg
     9181 ttttcgctgc cgatgatatc tgaaatcagc ctgttgcccc ccctggtgta gcgtatcatg
     9241 gcagtccgga cagggataat ctgtccggca gcgtttttta ccccggcgca ggaggccgat
     9301 aactggggct gcgcctggga agaccagacg gcaatctgcc cgccggcgcg ttcgcctctc
     9361 cagccggaca gacgcacggc atcctgaagc atttcctgcc cgggagcgcc attgtaagga
     9421 atacggtcat aatccttcac cgctgcagcc tgcaggctca gggcggcatc gggtccgtac
     9481 cctttgattt ccaccagatg cccccccttc tcattgccgg cgctattgcc caaaaaagtg
     9541 attttaacgt aacggaccgt ctgcggattg aatttgaagg gaacgccttc cggagtggcg
     9601 gcaatgctgt tggaagactg atccgccaac attttccagt tctttccgtc ttcggaacct
     9661 tctattttat atttgtaaat gcgccctccc tcccaatagg gccatacatg cagagaggaa
     9721 agcgtccggg gctttcccat atctatctgg agccagacgg gaatgccctc gcaaccccag
     9781 tatttgccgg cgttattcgt ctgcccgtcc acggccagtt ccggacggtc actgccgtaa
     9841 tgaccggaag cagttacttt ggctccggca aataaattac ctgcatcacc cggagttcct
     9901 gcggaaacaa gggcgggttc atacagggga tgcctctcca gggactgggc ctggacaaaa
     9961 gacgttaagg caatagcgga acacagagga aaaaaaagac agcgcatacg catattacgc
    10021 gccggaattt cattttctct caaaagaaaa gctgtttccg ctattccgcc aaaggacgca
    10081 cgggtattcc tctggaagca aagtaagcct tggcttccgg caccgtgtat tccccaaaat
    10141 ggaaaatgga agccgccagc acggcatccg ccttcccttc caccagcacg tccaccatgt
    10201 gatccaaatt acccgcaccc ccgctggcga ttaccggaat gcgcaccgca ctgcttacgg
    10261 cgcgggtcaa ttcaatatca taacccgttt tggctccgtc cgcatccatg ctggtcaaca
    10321 agatttcccc ggctccgcgg cgttccgcct ccacagccca ttccacggca tccagcccca
    10381 cgaatttccg gcctccatgg gtggaaacgc cccacttgcc ggaagcctgg cgcttggcgt
    10441 caatagcgac gacgatgcac tggctgccaa aagccgccgc accttcatta atcagctccg
    10501 gcctattgat ggccgccgta ttcagggaaa ccttgtccgc acccgccaga agcatttcgc
    10561 gcatgtcctt tacggaacgg atgccgccgc ctaccgtcag cggcatgaag cagcatgccg
    10621 ccgtgcggcg caccacgtcc gccatggtgg cacggccatc ggaagaagcg gtaatatcca
    10681 gaaaaacaag ttcatccgcc tgctgggcat catacgccct ggcacattct acaggatccc
    10741 cggcatctct caaattaatg aaattggtcc ccttgacgac cctgccgtcc gttacgtcca
    10801 gacacggaat gattctttta gccagcacgg ccctatcaag ccatcaccgc cgccaaagga
    10861 aaagcctaaa atacggcttg ccgcgggatg ccttttgata aacatgttcc ctttttgacc
    10921 aaggccctct tcggcagcgt ttccatcccg catatcccgg taagagaaat ttactgaaat
    10981 tcatcaatat cactattcca ctcactttcc ggccggccct gccccgccat gaagaaacgc
    11041 agtgcggcat ctgccccttt cccgcccgca tgcataaaac ggcctaagag cttttctttc
    11101 catgtccagg tggtagagtc cgcataaggc atttccattc atgaccacta cacgctcggg
    11161 attcaccaaa cttgcagccg tctgcattgc cattcttctg ggggcggtgg tctgggagct
    11221 gggctggccc ctgacgcggg cggaacatga gtggtcgcgg ctgattgcag ccgttgccac
    11281 gctgggccac ctgacgggta ttctgggttc ctatttccgg aaggaaatca accgcccttc
    11341 cctgaggctc ctgattttcc aaatcatcag ctgcctcatg atttttctcc tgattgccag
    11401 ggaacaacag gaagcgggat acatgaggtt cacggagctt tcccgcctgg tgattacggc
    11461 cgggctgatt gccatcccca cgctgatgtc cctgaccagg atttttgaat ggctggtggg
    11521 caagcaaaaa aaaggccggc ctcttatggc ccccgccatg cagtttgtag cttctctggg
    11581 agtagtcatc ctggcaggca ccggattgct tctgctgcct aattccacat atccgggtat
    11641 tacactcagt tttacggatg ccctgttcac cagcaccagc gcagtatgcg tcaccggtct
    11701 gaacgccgtg gattttgccc atacttttac cccgctggga gaaatgttca cgcttgccct
    11761 tatccagatt ggcggattcg gcatcatgac gttcgcctac ttcgtagcca tggtggcagg
    11821 ccagggtttt tccctgaggg accgcgtgct gctgacggat ctgcttgatg aagacaatct
    11881 gggagccgtc gtctccttta tcaccactat tgtggtcagt acgctgttca tcgaactgtg
    11941 cggcgccgtc cttctttatt tctcctggga agggaaggac atcaacctga tgggggagcc
    12001 tttgtggtgg cattccctgt tccactccgt ttccgccttc tgcaatgctg gtttttcaac
    12061 tttcccgatg aatttgatgg agccgggcat ccgcctgtgc tacagcgggc aggcggtcat
    12121 catggcgctg atcgtatgcg gcggcctggg attcggcatt tacaaggaaa ttaattcacg
    12181 cctggcaaac cgcttttttt ccaaacaccg ccgcctgcac atgcagtgga ccccttactt
    12241 caaactggtg atgatctcca cggggatttt gctggcggga ggcgccctgg ccatctttgc
    12301 cgtttcctct ccccatgccg cggaaccgtt gggggaacac ctctggattt gccttttcga
    12361 cagcgtcacg gcacgcacgg cgggattcaa tatcagcgac tacggccgct atctgcccgc
    12421 agccagcctc attatgtgcg gtctgatgat ggtgggaggc agccccggcg gcacggcagg
    12481 cggcatgaga accactacct gcgccattgc aggcgcggaa atcctgcgca tcctccgcgg
    12541 cagggatcat gtggaattct tccgccgccg catcgaccag cgcaccgtgg cgcgctgcgt
    12601 gattaccgtg gtggtctcct gcgcctggat cggctgcttt accgtcctga tttgcgccct
    12661 ggagccctcc atgagctctc tggatatctt ctttgaaaac tgcagcgctt ttgctacggt
    12721 aggcgtgtcg cggggcatta ctccagattt aagcggccct tccaaatacc ttcttatcgt
    12781 caacatgctc gccggccgcg tggggctctt cgcttttctc attgcgctgg ccggcacccc
    12841 tactccgagg cattaccgct atccatccgt caaaatcccg ttaacctgaa tataccatta
    12901 tgagatacac cgttatcggc ctgggccagt ttgggcagga actctgcaca gaactttccg
    12961 cccgtaatat tgaagtagta gccgttgcct ccacggatga agaattggag caaatcaagg
    13021 atctggtgac ttatgccgtg gtgacggatt acactaatcc ggccgctttg cgtgagttgg
    13081 aactggacga ccagtccgcc gtcattgtcg ccatcggaga cagttttgaa gaaaaccttc
    13141 tcgtcgtcac gcaccttcag aaaatgggcg tccgctacat ctacgcccgc gtcatgagtc
    13201 cggtgcacga acacatttta agccagatga acgtgtatgc gctcatcaac ttgtcccgcg
    13261 tggcttccaa gcaactcgcc agccagttgg aatccccgga attcctgcgc gtctccccca
    13321 tggacgaaaa ccacagcatc gtggaaatag ccgtgccgcg catctgggtg ggcaagcgcc
    13381 tgcgggatgt aggcttgcgc acggaacacc acctcaacct gctcaccatc cgccgtgggg
    13441 aggcccagac tccgcagggg cgccgggaaa tcctgtccat accgcgcatt cccgtcattg
    13501 gcaccccttc cccggatctc gtttttgaag accacgacat tctggtcctg ttcggcaaag
    13561 aaaccaattt gattgaattc gcccaattat ccaaaggatt gtaaaccatc ctccgcgagc
    13621 aggctgaggg tatccctctc catttcagaa aaaggcgccg gataagccgc ctgtgcaaac
    13681 agcctccgtc ctggttttac tggcttgaca atgcctcaaa agaagccacc agacgttttt
    13741 cggagacgcg gcccttgacg gagatggcgg gagcgaaaac ggccaggcgg tattcttcca
    13801 gcaaataacc gtattgcatc cagcgcaggt ctccggcatg ttccttcaaa acctgatgcc
    13861 agggaaaata cacgcgttca aagaggtcca ggcgttccaa ttccctggca aggggttgct
    13921 ggccgatgcg tctgatacgc tccgcaattc cctgcatgta ccgtttcagg tccggcaagc
    13981 gttccgctcc atgcgcccac aggaaacggg ggcgtaacaa ccagtcaagc tggcgctgaa
    14041 ggtcagccgt gatgcgctcc gtatggcgca cacccttttg cagcgccgta aagtccctga
    14101 cggcatgttc cgtacccgcc accagttccc atatatccgc cacgttatgc gctgcgtcaa
    14161 aaaggttttg gcgcagattc atttccgcag cagcgaattg ctccgccgtg cgcggcaaag
    14221 gacggcccat ggctatctct gcggcaacgt ccaccaggtc ttccgcattg gtagacggct
    14281 cccgtccgag catatgaaga gagagctttc cttccagctt caacggaaat tttctgcgga
    14341 gatggttaag ctggtccgtc tggcgcaggc gcatgaaacg caggcaccct tcccggtggg
    14401 attccgcagc atccagttca tcctcaaaga cacggacgcc cacggatgct ccttcatcca
    14461 ccagagccac ataacccggc cttcccgcca catccaccgt gtattccaaa tctccgcagc
    14521 tccattcctt catgccggtt acggacacga tatcctccgc tgtttcctgg aaccggcggg
    14581 aaagtttttt acccaggcgg ttattcagtt ccgcaacatc cgtgcccatg gcaagctctt
    14641 ccccttcatc atcgcacacc catattttcg taaccagctc cgcaggaaga cggttcatgt
    14701 caaaaaagga gggcgcgcaa aattttcccg tttccacttc cacaaattcc gccagtttcc
    14761 ccgccagcgg cccgtccggt tccaggtcat gcctcagttc cgcaaaataa gcggcctttt
    14821 ggctgatagg ctggagaaag acgcgcaaat ccttgggaag ggaacgcagc aggcattccg
    14881 cccgctgggc caaatgaccg ggaacccccc actccggcaa ccattcggga atatccggca
    14941 actggtcgat gtggacgccc agggtcacgc cgtcatcttc cgcgccggga tcattctggt
    15001 aatacacggc atattccgct cctttacagg tgatttcatc cggaaaacca tccagcaggt
    15061 ctttccccca gaattcgtac atggcttcct gtggcggaac atgcagagct tccgggtttt
    15121 tcttctccat accggcggcc caccgcaaaa aagccctggc cgtacagcag tccgggggaa
    15181 caagcctgtt aaagaattca aaaactcctt cctcacacca gacctggtcc ggacggcgca
    15241 acttcagctc tatctgccga acctcttccc ggagcgtttc cagatgcctg atacaggcgg
    15301 gtttcgtgcg gaaaccaccg cccaacaggc cttcacgtat cattatttcc cgcgcatggg
    15361 cgggattgat acggccatag tgcacacgcc tgttatcaat aatgcgcaag ccgccgcaca
    15421 cgacgcgttc cactgcgtaa acagccccct gctccctgtc ccaccgcgct ccggaatagt
    15481 gtgattcgca cagatggggc gctacccgct ccacccatcc cggttccaaa atggaggcgc
    15541 ggcgcatcca caggcgcgtg gtgtccacca actccacgcc cattacccat tcactccttt
    15601 ttttacggcg gaacaggccg gaaccgggaa aaatgccgaa ggaacgtcct ccggcgccgc
    15661 gatattcccg gttgtctgca tcccagaggc cgaactggcg cggaacgccc gccaggatgc
    15721 tccggtgaat catggcaaag gaagcctgcc gctccgtttc ttcttccaaa ggggaaattc
    15781 tgcatttcag tgtttccctg accagccggg aaaggtcctc ccataaattg aaccattcca
    15841 tcatgcggtt gaaattgagg aaatttttcc cgcaccattt ccgaagctgg tttttacgcc
    15901 agcgccttcc ctcccggaat tgccatgcag ccttccataa tttgagcaga gacaggaagt
    15961 cactgtcttc ttccttccac tgcgcgtgag cctggtccgc tttctgagcg gcatccgcag
    16021 ggcgttcacg gggatccatg atgcccaggc cggctacaat caccagcatt tccggcaggg
    16081 cctgttcatg ttgtgcctcc agcagcatgc gggccagccg tgggtcaatg ggcaaccgcg
    16141 ccagcttttt gcctacgggc gtgagctgcc gggctttgtc cagagcgccg atctcccgta
    16201 aggtgcggta accttccgtc accagtttgg atgaaggagg atccggaagt gggaactccg
    16261 gcatttccgg caatcccagg tctttcatcc ggagcagcgc cccggccagt gcgctgcgcc
    16321 tgatttccgg gtccgtaaaa tccggcctgt cctcccagtc cttctcactg tacaggcgga
    16381 tgcacacacc ttcgcacaca cggccgcaac ggccggcgcg ctggcgggcg ctggccttgg
    16441 agacg
//
